PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ARFGAP3	1	CD14	3	two hybrid	Wang J (2011)	1
TAF9	2	TAF1	9	affinity chromatography technology, affinity chromatography technology	Martinez E (2001), Gupta K (2017)	2
CD14	3	LBP	2	pull down, biochemical	Thomas CJ (2002), Yu B (1995)	2
CD14	3	ARID2	5	affinity chromatography technology	Hein MY (2015)	1
CD14	3	PPP3R2	0	two hybrid	Wang J (2011)	1
CD14	3	WDCP	2	affinity chromatography technology	Hein MY (2015)	1
CD14	3	BUB1B	0	affinity chromatography technology	Hein MY (2015)	1
CD14	3	TAF1	9	affinity chromatography technology	Hein MY (2015)	1
CD14	3	SVIL	9	affinity chromatography technology	Hein MY (2015)	1
CD14	3	TAF9	2	affinity chromatography technology	Hein MY (2015)	1
LTF	2	CD14	3	pull down	Baveye S (2000)	1
CD14	3	PPP1R12B	2	affinity chromatography technology	Hein MY (2015)	1
CD14	3	ANXA7	0	affinity chromatography technology	Hein MY (2015)	1
CD14	3	OASL	1	affinity chromatography technology	Hein MY (2015)	1
CD14	3	PHF20L1	4	affinity chromatography technology	Hein MY (2015)	1
CD14	3	ICAM5	0	affinity chromatography technology	Hein MY (2015)	1
CD14	3	IRAK3	0	two hybrid	Wang J (2011)	1
CD14	3	PHF21A	4	affinity chromatography technology	Hein MY (2015)	1
CD14	3	POLR2J	0	two hybrid	Wang J (2011)	1
CD14	3	HPS5	4	affinity chromatography technology	Hein MY (2015)	1
CD14	3	BCAS3	4	affinity chromatography technology	Hein MY (2015)	1
CD14	3	TLR2	0	affinity chromatography technology	Yang RB (1999)	1
CD14	3	AP3S1	0	affinity chromatography technology	Hein MY (2015)	1
CD14	3	TNFRSF1B	4	two hybrid	Wang J (2011)	1
CD14	3	EXO1	3	affinity chromatography technology	Hein MY (2015)	1
CD14	3	GJB2	1	two hybrid	Wang J (2011)	1