PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
FN1	17	UBE2M	0	affinity chromatography technology	Humphries JD (2009)	1
DUSP23	1	UBE2M	0	affinity chromatography technology	Li X (2016)	1
CUL3	17	CUL1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Bennett EJ (2010), Bennett EJ (2010), Wan C (2015)	3
PRKN	1	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imai Y (2003), Sarraf SA (2013), Huttlin EL (2017)	3
NAE1	0	UBA3	0	two hybrid, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, biochemical, pull down, biochemical, biochemical, pull down, pull down, biochemical	Chen Y (2000), Chen Y (2000), Huang DT (2008), Huang DT (2007), Walden H (2003), Bohnsack RN (2003), Osaka F (1998), Havugimana PC (2012), Kristensen AR (2012), Huang DT (2004), Gong L (1999), Wan C (2015)	12
SMURF1	4	UBE2D2	0	pull down, pull down	Kristariyanto YA (2015), Andrews PS (2010)	2
DCUN1D1	0	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	SMURF1	4	pull down, affinity chromatography technology, pull down	Xie P (2014), Xie P (2014), He S (2017)	3
TP53	0	COPS4	0	affinity chromatography technology	Bhansali M (2014)	1
VCP	6	UBE2M	0	affinity chromatography technology	Yu CC (2013)	1
CUL5	1	PCBP1	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXO7	1	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL2	3	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015)	3
NEDD4	2	RBX1	2	affinity chromatography technology	Liu J (2014)	1
CUL3	17	CDC5L	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	KLHL42	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cummings CM (2009), Cummings CM (2009), Bennett EJ (2010), Plafker KS (2009), Olma MH (2009), Wimuttisuk W (2014), Huttlin EL (2017)	7
ITGA4	4	VCP	6	affinity chromatography technology	Byron A (2012)	1
GPS1	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Stotland A (2012), Huang X (2005), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
CCDC22	1	CUL3	17	affinity chromatography technology	Starokadomskyy P (2013)	1
CAND1	2	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	MEPCE	1	affinity chromatography technology	Bennett EJ (2010)	1
VCP	6	SEC22B	0	affinity chromatography technology	Yu CC (2013)	1
COPS6	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
CAND1	2	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	RHOBTB1	0	affinity chromatography technology	Huttlin EL (2017)	1
UBE2M	0	KLHL20	2	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
COPS5	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	11
RBX1	2	CUL2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Dias DC (2002), Ohta T (1999), Ohta T (1999), Maine GN (2007), Hu J (2004), Furukawa M (2002), Mao X (2011), Sufan RI (2006), Sufan RI (2006), Sufan RI (2006), Brower CS (2002), Tron AE (2012), Kamura T (2004), Kristensen AR (2012), Costessi A (2011), Huang DT (2009), Kamura T (1999), Kamura T (1999), Xu J (2015), Cardote TAF (2017)	20
UBE2M	0	PCBP1	2	biochemical	Wan C (2015)	1
COPS4	0	COPS7B	0	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
SNW1	0	COPS6	0	affinity chromatography technology	Lleres D (2010)	1
UBE2M	0	KLHL42	1	affinity chromatography technology	Huttlin EL (2017)	1
PCBP1	2	LMNA	2	two hybrid, affinity chromatography technology, affinity chromatography technology, bioid, biochemical	Zhong N (2005), Zhong N (2005), Ju WN (2009), Roux KJ (2012), Wan C (2015)	5
CDC5L	2	UBE2M	0	affinity chromatography technology	Lleres D (2010)	1
VCP	6	CUL7	4	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Hanson D (2014)	2
CUL5	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Zhu Z (2017)	3
PRKAR1A	4	UBE2M	0	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ewing RM (2007)	2
COPS5	0	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	KCTD3	2	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	KBTBD6	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	COPS5	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
COPS7A	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	4
RBX1	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Pick E (2007), Lan L (2012), Tsai WB (2010), Hrecka K (2007), Okuda H (2001), Tai T (2006), Ahn J (2011), Gong B (2010), Lu Y (2012), Ohta A (2013), da Silva Almeida AC (2013), Delucia M (2013), Scott DC (2014), Camp ND (2012), Kim S (2014), Theurillat JP (2014), Kigoshi Y (2011), Pashkova N (2010), Beck J (2013), Pierce WK (2015), Wu K (2016), Parameswaran B (2015), Simo S (2013), Groisman R (2006), Marzahn MR (2016), Courtheoux T (2016), Hasanov E (2017), Ferretti LP (2016), Zhou X (2017), Kroenke J (2014), Mulvaney KM (2016)	31
CCDC22	1	UBE2M	0	affinity chromatography technology	Hein MY (2015)	1
UBE2M	0	KHDC4	0	biochemical	Wan C (2015)	1
DCUN1D1	0	CAND1	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Bommelje CC (2013), Kim AY (2008), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	11
CUL5	1	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D2	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
KLHL18	2	RBX1	2	affinity chromatography technology	Moghe S (2012)	1
EWSR1	2	UBE2T	0	bioid	Elzi DJ (2014)	1
PRKN	1	FBXO7	1	affinity chromatography technology, pull down, pull down	Burchell VS (2013), Burchell VS (2013), Burchell VS (2013)	3
KBTBD6	0	RBX1	2	affinity chromatography technology	Genau HM (2015)	1
UBE2M	0	KBTBD6	0	affinity chromatography technology	Huttlin EL (2017)	1
FBXO7	1	PINK1	2	affinity chromatography technology, pull down	Burchell VS (2013), Burchell VS (2013)	2
KRAS	1	NAE1	0	genetic interference	Luo J (2009)	1
KRAS	1	COPS5	0	genetic interference	Luo J (2009)	1
MARCH7	0	UBE2D2	0	pull down	Flach K (2014)	1
UBE2M	0	KLHL18	2	affinity chromatography technology	Huttlin EL (2017)	1
DCUN1D3	1	CUL3	17	pull down, affinity chromatography technology, pull down, imaging technique, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	11
DCUN1D2	0	CUL5	1	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
GPS1	1	TP53	0	biochemical	Bech-Otschir D (2001)	1
SMURF1	4	PRKAR1A	4	affinity chromatography technology	Xie Y (2013)	1
CUL5	1	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
FN1	17	LMNA	2	affinity chromatography technology	Humphries JD (2009)	1
PRKN	1	UBE2T	0	pull down	Kazlauskaite A (2014)	1
NEDD8	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
SOD1	0	UBE2M	0	affinity chromatography technology	Malty RH (2017)	1
DCUN1D1	0	COPS6	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	KLHL18	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	CDK2	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	KLHL42	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	RHOBTB1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Berthold J (2008), Berthold J (2008), Berthold J (2008), Pelham CJ (2012), Pelham CJ (2012), Ibeawuchi SR (2015)	7
PRKN	1	CUL1	7	affinity chromatography technology, pull down, affinity chromatography technology	Staropoli JF (2003), Staropoli JF (2003), Gong Y (2014)	3
DCUN1D5	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
UBE2M	0	RANBP2	9	affinity chromatography technology, affinity chromatography technology	Zhu T (2016), Zhu T (2016)	2
SMURF1	4	LMNA	2	enzymatic study	Andrews PS (2010)	1
DCUN1D1	0	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
RANBP2	9	MDM2	2	enzymatic study	Miyauchi Y (2002)	1
COPS2	5	COPS4	0	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huang X (2005), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	8
UBE2M	0	UBE2M	0	pull down, biochemical	David Y (2010), Ohki Y (2009)	2
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
CDK2	0	PRKAR1A	4	affinity chromatography technology, enzymatic study, affinity chromatography technology	Gupte RS (2006), Gupte RS (2006), Gupte RS (2006)	3
COPS5	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Bennett EJ (2010), Oh W (2006), Chun Y (2013), Chun Y (2013), Chun Y (2013), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
DCUN1D5	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
CUL1	7	RANBP2	9	two hybrid	Wang J (2011)	1
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
KHDC4	0	CDC5L	2	affinity chromatography technology	Grillari J (2009)	1
VCAM1	2	LMNA	2	affinity chromatography technology	Humphries JD (2009)	1
COPS5	0	CAND1	2	biochemical, affinity chromatography technology	Bornstein G (2006), Bennett EJ (2010)	2
SNW1	0	PCBP1	2	affinity chromatography technology	Lleres D (2010)	1
COPS5	0	KCTD6	2	affinity chromatography technology	Bennett EJ (2010)	1
VCAM1	2	EWSR1	2	affinity chromatography technology	Humphries JD (2009)	1
CUL2	3	PCBP1	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	RNF111	2	two hybrid, two hybrid, pull down, pull down, pull down, pull down	van Wijk SJ (2009), Markson G (2009), Erker Y (2013), Wright JD (2016), Birkou M (2017), Birkou M (2017)	6
FBXO7	1	PCBP2	3	affinity chromatography technology	Teixeira FR (2016)	1
DCUN1D1	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Wu K (2011), Bennett EJ (2010), Huang G (2011), Monda JK (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Huang G (2014), Huang G (2014), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	16
CUL3	17	SHKBP1	4	affinity chromatography technology, two hybrid, pull down	Bennett EJ (2010), Wang J (2011), Pinkas DM (2017)	3
RNF111	2	DCUN1D5	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL3	17	KBTBD6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Genau HM (2015), Genau HM (2015), Huttlin EL (2017)	5
SMURF1	4	NEDD8	0	affinity chromatography technology, pull down	He S (2017), He S (2017)	2
COPS2	5	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Huang X (2005), Bennett EJ (2010), Olma MH (2009), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	6
KRAS	1	COPS7B	0	affinity chromatography technology	Hein MY (2015)	1
DCUN1D3	1	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
SOD1	0	VCP	6	affinity chromatography technology	Malty RH (2017)	1
FBXO7	1	LMNA	2	enzymatic study	Teixeira FR (2016)	1
CUL5	1	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	RNF7	0	two hybrid, pull down	Markson G (2009), Kershaw NJ (2014)	2
NEDD8	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
SAE1	0	APP	1	pull down	Olah J (2011)	1
CUL3	17	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Schenkova K (2012)	3
CUL1	7	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	UBE2D2	0	x-ray crystallography	Sakata E (2007)	1
COPS6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Reitsma JM (2017)	7
UBE2M	0	CUL7	4	enzymatic study	Ponyeam W (2012)	1
VCAM1	2	PCBP1	2	affinity chromatography technology	Humphries JD (2009)	1
CDK2	0	LMNA	2	affinity chromatography technology	Neganova I (2011)	1
DCUN1D5	0	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bommelje CC (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	4
UBE2M	0	CUL3	17	enzymatic study, pull down	Huang G (2011), Schumacher FR (2015)	2
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
UBE2M	0	APP	1	enzymatic study, pull down	Lee MR (2008), Olah J (2011)	2
PINK1	2	UBE2M	0	affinity chromatography technology, enzymatic study	Choo YS (2012), Choo YS (2012)	2
NEDD8	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
EWSR1	2	SAE1	0	bioid	Elzi DJ (2014)	1
CUL3	17	VCP	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Besten Wd (2012)	2
CUL7	4	PRDX1	1	affinity chromatography technology	Hanson D (2014)	1
DCUN1D4	0	CUL1	7	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
CUL2	3	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL7	4	PCBP1	2	affinity chromatography technology	Hanson D (2014)	1
CUL7	4	SNW1	0	affinity chromatography technology	Hanson D (2014)	1
RNF111	2	MARCH7	0	two hybrid	Woodsmith J (2012)	1
DCUN1D2	0	CAND1	2	affinity chromatography technology, affinity chromatography technology, pull down	Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	3
COPS7B	0	APP	1	pull down	Olah J (2011)	1
UBE2M	0	SHKBP1	4	affinity chromatography technology	Huttlin EL (2017)	1
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
COPS7A	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
COPS6	0	UBE2M	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
NEDD8	0	KBTBD6	0	affinity chromatography technology	Bennett EJ (2010)	1
RBX1	2	APP	1	pull down	Olah J (2011)	1
UBE2D2	0	UBE2M	0	biochemical	Havugimana PC (2012)	1
FBXO7	1	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
KBTBD7	3	KBTBD6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Genau HM (2015), Genau HM (2015), Hein MY (2015), Huttlin EL (2017)	5
CUL2	3	GPS1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001)	2
CUL1	7	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Lee JE (2011), Bennett EJ (2010), Lyapina S (2001), Reitsma JM (2017)	6
UBE2M	0	UBA3	0	affinity chromatography technology, enzymatic study, pull down, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Ewing RM (2007), Huang DT (2004), Souphron J (2008), Huang DT (2005), Huang DT (2009), Gong L (1999), Souphron J (2008), Huttlin EL (2017), Mo Z (2016)	9
CUL3	17	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huang X (2016), Huttlin EL (2017)	3
UBE2M	0	PCED1A	0	affinity chromatography technology	Ewing RM (2007)	1
UBE2M	0	RNF111	2	two hybrid	Markson G (2009)	1
CUL7	4	APP	1	affinity chromatography technology	Hanson D (2014)	1
COPS6	0	SHKBP1	4	affinity chromatography technology	Sowa ME (2009)	1
DCUN1D1	0	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
COPS2	5	FBXO7	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL3	17	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001), Huttlin EL (2017)	3
KRAS	1	COPS4	0	genetic interference	Luo J (2009)	1
VCAM1	2	UBE2M	0	affinity chromatography technology	Humphries JD (2009)	1
CDK2	0	GARS	1	affinity chromatography technology	Neganova I (2011)	1
NEDD8	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
LMNA	2	VAMP2	3	two hybrid	Dittmer TA (2014)	1
COPS6	0	KLHL18	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
UBE2M	0	PRKN	1	enzymatic study	Choo YS (2012)	1
COTL1	0	PCBP1	2	biochemical	Wan C (2015)	1
COPS6	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
COPS5	0	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Bhansali M (2014), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	13
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
UBE2M	0	PCBP2	3	biochemical	Wan C (2015)	1
CUL1	7	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina SA (1998), Huttlin EL (2015), Huttlin EL (2017)	4
SOD1	0	PCBP1	2	biochemical	Wan C (2015)	1
COPS7B	0	BTBD1	2	affinity chromatography technology	Huttlin EL (2017)	1
DCUN1D3	1	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
DLD	1	AP1S2	1	affinity chromatography technology	Malty RH (2017)	1
CUL5	1	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
COPS2	5	UBA3	0	genetic interference	Horlbeck MA (2018)	1
MDM2	2	NEDD4	2	unspecified method, enzymatic study, affinity chromatography technology	Burch LR (2004), Xu C (2014), Xu C (2014)	3
COPS6	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
COPS2	5	COPS7B	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
COPS6	0	KLHL24	1	affinity chromatography technology	Sowa ME (2009)	1
CUL3	17	KCTD3	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CUL3	17	KCTD6	2	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lange S (2012), Rolland T (2014), Smaldone G (2015), Ji AX (2016), Heride C (2016), Huttlin EL (2017)	7
CUL7	4	SEC22B	0	affinity chromatography technology	Hanson D (2014)	1
UBE2M	0	TERF1	1	enzymatic study	Jeong YY (2016)	1
RNF7	0	CUL3	17	enzymatic study	Huang DT (2009)	1
COPS6	0	KLHL20	2	affinity chromatography technology	Sowa ME (2009)	1
DCUN1D4	0	CUL2	3	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
SEC22B	0	UBE2M	0	biochemical	Havugimana PC (2012)	1
CUL3	17	NISCH	11	affinity chromatography technology	Bennett EJ (2010)	1
NPRL2	2	PRKAR1A	4	affinity chromatography technology	Ewing RM (2007)	1
FN1	17	SEC22B	0	affinity chromatography technology	Humphries JD (2009)	1
CDC5L	2	RANBP2	9	affinity chromatography technology	Lleres D (2010)	1
VCAM1	2	VCP	6	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Braunstein I (2015)	2
DLD	1	UBE2M	0	affinity chromatography technology	Malty RH (2017)	1
VCP	6	APP	1	affinity chromatography technology	Jang JK (2017)	1
COPS5	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
CDK2	0	VCP	6	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Fogeron ML (2013)	2
NEDD8	0	UBA3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li T (2006), Norman JA (2006), Bennett EJ (2010)	3
NPRL2	2	UBE2M	0	affinity chromatography technology	Ewing RM (2007)	1
CDC5L	2	PCBP2	3	affinity chromatography technology	Lleres D (2010)	1
CUL2	3	UBE2M	0	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	RBX1	2	affinity chromatography technology	Lyapina S (2001)	1
UBE2M	0	COPS5	0	affinity chromatography technology	Huttlin EL (2017)	1
RBX1	2	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Furukawa M (2005), Hu J (2004), Furukawa M (2002), Ichikawa T (2009), Ichikawa T (2009), Lee DF (2009), Tron AE (2012), Oshikawa K (2003), Plafker KS (2009), Lu A (2013), Meyer-Schaller N (2009), Theurillat JP (2014), Huang DT (2009), Ibeawuchi SR (2015), Schumacher FR (2015), Kasahara K (2014), Kasahara K (2014)	18
COPS5	0	CDK2	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Chun Y (2013)	2
SNW1	0	RANBP2	9	affinity chromatography technology	Lleres D (2010)	1
EWSR1	2	UBE2M	0	bioid	Elzi DJ (2014)	1
RBX1	2	DCUN1D3	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meyer-Schaller N (2009), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	4
DCUN1D1	0	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
FN1	17	PRDX1	1	affinity chromatography technology	Humphries JD (2009)	1
UBE2M	0	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
UBE2M	0	NAE1	0	affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology	Ewing RM (2007), Huang DT (2007), Souphron J (2008), Huang DT (2009), Huttlin EL (2017)	5
NEDD4	2	DCUN1D1	0	enzymatic study	Wu K (2011)	1
CUL5	1	GARS	1	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D4	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
DCUN1D5	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
CUL7	4	PRKAR1A	4	affinity chromatography technology	Hanson D (2014)	1
SLC9A3R2	8	TST	0	biochemical	Havugimana PC (2012)	1
DCUN1D5	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bommelje CC (2013), Keuss MJ (2016), Keuss MJ (2016)	3
MEPCE	1	UBE2M	0	affinity chromatography technology	Jeronimo C (2007)	1
COTL1	0	UBE2M	0	biochemical	Wan C (2015)	1
DCUN1D3	1	CUL1	7	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	8
UBE2M	0	DCUN1D3	1	pull down, pull down, pull down	Monda JK (2013), Meyer-Schaller N (2009), Keuss MJ (2016)	3
APP	1	NAE1	0	pull down, affinity chromatography technology	Chow N (1996), Chow N (1996)	2
COPS5	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Christmann M (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Scherer PC (2016), Huttlin EL (2017), Boldt K (2016)	15
CDC5L	2	COPS5	0	affinity chromatography technology	Lleres D (2010)	1
COPS2	5	TP53	0	affinity chromatography technology	Huang X (2005)	1
CUL1	7	PCBP2	3	affinity chromatography technology	Bennett EJ (2010)	1
ITGA4	4	CBL	7	affinity chromatography technology	Byron A (2012)	1
TP53	0	LMNA	2	affinity chromatography technology	Horikawa I (2014)	1
VCAM1	2	TYMS	0	affinity chromatography technology	Humphries JD (2009)	1
COPS5	0	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Cayli S (2009), Cayli S (2009), Cayli S (2009), Cayli S (2009), Bennett EJ (2010)	5
CUL1	7	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Inuzuka H (2010), Inuzuka H (2010), He Y (2014)	3
DLD	1	VCP	6	affinity chromatography technology	Malty RH (2017)	1
ITGA4	4	PRDX1	1	affinity chromatography technology	Byron A (2012)	1
COPS5	0	PCBP2	3	affinity chromatography technology	Bennett EJ (2010)	1
FBXO7	1	NEDD8	0	affinity chromatography technology	Teixeira FR (2016)	1
NEDD8	0	NAE1	0	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology	Li T (2006), Norman JA (2006), Huang DT (2008), Huang DT (2007), Bennett EJ (2010)	5
CUL5	1	CUL1	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
RBX1	2	UBE2M	0	pull down, pull down, pull down, pull down, x-ray crystallography, pull down, pull down, two hybrid, pull down, pull down, pull down, pull down, enzymatic study, pull down	Okuda H (2001), Yoshida Y (2005), Choi YS (2010), Calabrese MF (2011), Calabrese MF (2011), Kim AY (2008), Scott DC (2014), Markson G (2009), Sufan RI (2006), Huang DT (2009), Morimoto M (2003), Ohki Y (2009), Ohki Y (2009), Wang X (2015)	14
DUSP23	1	KBTBD7	3	two hybrid	Vinayagam A (2011)	1
UBE2M	0	COPS2	5	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
CUL1	7	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Dias DC (2002), Kim J (2002), Zheng N (2002), Kim AY (2008), Ohta T (1999), Ohta T (1999), Ohta T (1999), Bloom J (2006), Block K (2005), Hu J (2004), Hwang JW (2003), Furukawa M (2002), Kawakami T (2001), Ohta T (2001), Chen A (2000), Read MA (2000), Wu K (2000), Tan P (1999), Banerjee S (2010), Gao D (2010), Tron AE (2012), Tron AE (2012), Shteingart S (2012), Tan M (2010), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Huang DT (2004), Emberley ED (2012), Gastaldello S (2012), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Li X (2003), Calabrese MF (2011), Scott DC (2014), Scott DC (2014), Siergiejuk E (2009), Zhou W (2014), Zhou W (2014), Huang DT (2009), Pick E (2007), Morimoto M (2003), Morimoto M (2003), Ohki Y (2009), Duda DM (2008), Duda DM (2008), Wan C (2015), Hao J (2015), Hao J (2015), Han XR (2016), Kuang P (2016), Zhou W (2017), Hu Y (2017), Reitsma JM (2017)	59
UBE2M	0	GARS	1	pull down, affinity chromatography technology, pull down	Mo Z (2016), Mo Z (2016), Mo Z (2016)	3
KRAS	1	SAE1	0	genetic interference	Luo J (2009)	1
DCUN1D4	0	CUL3	17	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	5
CBL	7	UBE2M	0	affinity chromatography technology, pull down	Oved S (2006), Zuo W (2013)	2
DCUN1D1	0	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	CUL1	7	enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Huang G (2011), Huang G (2011), Kim AY (2008), Ponyeam W (2012), Ohki Y (2009), Zhou W (2017), Mo Z (2016)	7
TP53	0	RBX1	2	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huang X (2016), Huttlin EL (2017)	5
COPS2	5	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS7A	0	COPS2	5	affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
COPS6	0	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
EWSR1	2	KHDC4	0	bioid	Elzi DJ (2014)	1
CDK2	0	PCED1A	0	affinity chromatography technology	Ewing RM (2007)	1
PRKN	1	APP	1	affinity chromatography technology, imaging technique	Rosen KM (2010), Lonskaya I (2012)	2
CUL1	7	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Reitsma JM (2017)	6
COPS5	0	KLHL18	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
ITCH	1	UBE2D2	0	pull down, pull down, pull down, pull down	Sheng Y (2012), Fang S (2001), Kristariyanto YA (2015), Riling C (2015)	4
CUL1	7	CCDC22	1	affinity chromatography technology, affinity chromatography technology	Starokadomskyy P (2013), Starokadomskyy P (2013)	2
CUL3	17	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
CUL3	17	KLHL18	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Moghe S (2012), Moghe S (2012), Huttlin EL (2017)	5
FBXO7	1	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
FN1	17	ITGA4	4	affinity chromatography technology	Humphries JD (2009)	1
FN1	17	PCBP1	2	affinity chromatography technology	Humphries JD (2009)	1
CUL3	17	PRKAR1A	4	affinity chromatography technology	Bennett EJ (2010)	1
VCAM1	2	PCBP2	3	affinity chromatography technology	Humphries JD (2009)	1
NEDD8	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012)	4
TP53	0	EWSR1	2	affinity chromatography technology	Li Y (2012)	1
PRDX1	1	UBE2M	0	biochemical	Wan C (2015)	1
KRAS	1	APP	1	pull down	Olah J (2011)	1
VCP	6	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bennett EJ (2010), Besten Wd (2012)	3
CAND1	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chua YS (2011), Chua YS (2011), Tron AE (2012), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Liu J (2002), Huttlin EL (2017)	8
DCUN1D1	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	CUL5	1	enzymatic study	Duda DM (2008)	1
CDK2	0	NEDD8	0	affinity chromatography technology	Ewing RM (2007)	1
CDC5L	2	PCBP1	2	affinity chromatography technology	Lleres D (2010)	1
UBE2D2	0	FBXO7	1	enzymatic study, pull down	Cenciarelli C (1999), Teixeira FR (2016)	2
CUL2	3	SNW1	0	affinity chromatography technology	Bennett EJ (2010)	1
SAE1	0	TYMS	0	biochemical	Wan C (2015)	1
SNW1	0	RAD18	3	affinity chromatography technology	Lleres D (2010)	1
NEDD8	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
COPS6	0	KCTD3	2	affinity chromatography technology	Sowa ME (2009)	1
DCUN1D4	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
RANBP2	9	PRKN	1	affinity chromatography technology, pull down, enzymatic study	Um JW (2006), Um JW (2006), Um JW (2006)	3
UBE2D2	0	CBL	7	pull down, x-ray crystallography, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Joazeiro CA (1999), Dou H (2012), Dou H (2012), Sehat B (2008), Kassenbrock CK (2004), Roxburgh P (2012), Tsukahara F (2010), Bulut GB (2013), Buetow L (2016), Conte A (2017)	10
CUL3	17	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
CUL2	3	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	KLHL24	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
SMURF1	4	TP53	0	affinity chromatography technology	Nie J (2010)	1
NEDD8	0	TST	0	biochemical	Havugimana PC (2012)	1
SNW1	0	UBE2M	0	affinity chromatography technology	Lleres D (2010)	1
SNW1	0	LMNA	2	affinity chromatography technology	Lleres D (2010)	1
MYH13	9	UBE2M	0	affinity chromatography technology	Hein MY (2015)	1
AP1S2	1	UBE2M	0	affinity chromatography technology	Hein MY (2015)	1
ITCH	1	CBL	7	affinity chromatography technology	Azakir BA (2009)	1
FN1	17	VCP	6	affinity chromatography technology	Humphries JD (2009)	1
LMNA	2	RANBP2	9	bioid	Roux KJ (2012)	1
TST	0	UBE2M	0	biochemical	Havugimana PC (2012)	1
DCUN1D1	0	CUL5	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
DCUN1D1	0	COPS5	0	affinity chromatography technology	Bennett EJ (2010)	1
SMURF1	4	VCP	6	affinity chromatography technology	Xie Y (2013)	1
GARS	1	NEDD8	0	pull down, affinity chromatography technology, pull down	Mo Z (2016), Mo Z (2016), Mo Z (2016)	3
SNW1	0	CAND1	2	affinity chromatography technology	Lleres D (2010)	1
DCUN1D3	1	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
COPS5	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CUL5	1	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
VCP	6	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Zhang Z (2015)	3
CUL3	17	PCBP2	3	affinity chromatography technology	Bennett EJ (2010)	1
ITCH	1	PCBP2	3	affinity chromatography technology, affinity chromatography technology	You F (2009), You F (2009)	2
DCUN1D5	0	CUL3	17	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	7
PRDX1	1	SOD1	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
COPS6	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	6
MDM2	2	UBE2M	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Xirodimas DP (2004), Batuello CN (2015), Batuello CN (2015), Batuello CN (2015)	4
DCUN1D1	0	CUL2	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Monda JK (2013), Heir P (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Chen K (2016)	13
SEC22B	0	TST	0	biochemical	Havugimana PC (2012)	1
CUL3	17	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sumara I (2007), Bennett EJ (2010), Olma MH (2009), Wimuttisuk W (2014), Maerki S (2009), Huttlin EL (2017)	6
UBE2M	0	TP53	0	enzymatic study	Xirodimas DP (2004)	1
SLC9A3R2	8	UBE2M	0	biochemical	Havugimana PC (2012)	1
CUL2	3	RANBP2	9	affinity chromatography technology	Bennett EJ (2010)	1
CDC5L	2	LMNA	2	affinity chromatography technology, affinity chromatography technology	Lleres D (2010), Depreux FF (2015)	2
DLD	1	COPS4	0	affinity chromatography technology	Malty RH (2017)	1
CUL3	17	ITCH	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL7	4	CDC5L	2	affinity chromatography technology	Hanson D (2014)	1
RANBP2	9	VCP	6	biochemical	Wan C (2015)	1
GPS1	1	COPS7A	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015), Hein MY (2015), Huang X (2016)	6
CDK2	0	CAND1	2	affinity chromatography technology	Neganova I (2011)	1
CAND1	2	UBE2M	0	pull down	Kim AY (2008)	1
DCUN1D1	0	KCTD3	2	affinity chromatography technology	Bennett EJ (2010)	1
ITGA4	4	TYMS	0	affinity chromatography technology	Byron A (2012)	1
NEDD4	2	UBE2D2	0	two hybrid, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Hatakeyama S (1997), Anan T (1998), Sehat B (2008), Arevalo JC (2006), Woelk T (2006), Persaud A (2009), Zeng F (2009), Sarkari F (2013), Liu PY (2012), Sugeno N (2014), Bustos F (2015), Chesarino NM (2015), Sun M (2016)	13
TP53	0	CUL7	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Andrews P (2006), Andrews P (2006), Andrews P (2006), Dowell JD (2007), Dowell JD (2007), Dowell JD (2007), Skaar JR (2007), Skaar JR (2007), Kim SS (2007), Kim SS (2007), Kim SS (2007), Kaustov L (2007), Kasper JS (2006), Kasper JS (2006), Kasper JS (2006), Fogeron ML (2013), Hanson D (2014), Hanson D (2014), Huttlin EL (2015), Li X (2015), Huttlin EL (2017), Guo H (2014)	22
DCUN1D1	0	CUL3	17	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Huang G (2014), Huang G (2014), Monda JK (2013), Wan C (2015), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Huttlin EL (2017)	19
FBXO7	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Kirk R (2008), Hsu JM (2004), Hagens O (2006), Bennett EJ (2010), Hein MY (2015), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Reitsma JM (2017), Reitsma JM (2017)	11
PRKN	1	TP53	0	pull down, enzymatic study	Jung YY (2017), Jung YY (2017)	2
COPS5	0	SHKBP1	4	affinity chromatography technology	Bennett EJ (2010)	1
VCP	6	CUL5	1	affinity chromatography technology	Yu CC (2013)	1
COPS5	0	RHOBTB1	0	affinity chromatography technology	Bennett EJ (2010)	1
LMNA	2	SEC22B	0	two hybrid	Dittmer TA (2014)	1
UBE2M	0	UBE2V2	0	biochemical	Wan C (2015)	1
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
CUL3	17	KLHL24	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
SEC22B	0	VAMP2	3	biochemical	Havugimana PC (2012)	1
COPS4	0	UBA3	0	genetic interference	Horlbeck MA (2018)	1
SNW1	0	CUL1	7	affinity chromatography technology	Lleres D (2010)	1
CDK2	0	PCBP2	3	affinity chromatography technology	Neganova I (2011)	1
DCUN1D4	0	RBX1	2	affinity chromatography technology	Keuss MJ (2016)	1
SMURF1	4	APP	1	pull down	Olah J (2011)	1
MDM2	2	SMURF1	4	pull down, affinity chromatography technology, affinity chromatography technology	Nie J (2010), Nie J (2010), Nie J (2010)	3
VCP	6	COPS7A	0	affinity chromatography technology	Yu CC (2013)	1
CUL7	4	PCBP2	3	affinity chromatography technology	Hanson D (2014)	1
NEDD4	2	UBE2M	0	pull down	Persaud A (2009)	1
RNF7	0	UBE2M	0	pull down	Huang DT (2009)	1
CUL1	7	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Min KW (2005), Min KW (2005), Yang X (2002), Yang X (2002), Huang X (2005), Bennett EJ (2010), Scherer PC (2016), Scherer PC (2016), Reitsma JM (2017)	9
KRAS	1	COPS2	5	genetic interference	Luo J (2009)	1
RAD18	3	UBE2M	0	affinity chromatography technology	Guan J (2017)	1
DCUN1D2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Keuss MJ (2016), Keuss MJ (2016)	2
RANBP2	9	TP53	0	enzymatic study	Gareau JR (2012)	1
GPS1	1	COPS7B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Stotland A (2012), Havugimana PC (2012), Huang X (2016), Huttlin EL (2017)	4
CDC5L	2	RAD18	3	affinity chromatography technology	Lleres D (2010)	1
DCUN1D1	0	NEDD8	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	KBTBD6	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
COPS4	0	KLHL18	2	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	UBE2M	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li T (2006), Norman JA (2006), Huttlin EL (2017)	3
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
NEDD4	2	RNF7	0	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Persaud A (2009), Zhou W (2014), Zhou W (2014), Zhou W (2014)	4
DCUN1D3	1	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Huang G (2014), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	6
RBX1	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Norman JA (2006)	2
COPS6	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009)	5
COPS6	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Sharon M (2009), Bennett EJ (2010), Lingaraju GM (2014), Huttlin EL (2015), Huttlin EL (2017)	7
EWSR1	2	COPS7B	0	bioid	Elzi DJ (2014)	1
DCUN1D5	0	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
CUL2	3	PCBP2	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	3
CUL2	3	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Menon S (2008), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012)	7
CDK2	0	PCBP1	2	affinity chromatography technology	Neganova I (2011)	1
TP53	0	UBE2V2	0	two hybrid	Daakour S (2016)	1
UBE2M	0	UBE2T	0	biochemical	Havugimana PC (2012)	1
DCUN1D2	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
VCAM1	2	ITGA4	4	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Byron A (2012)	2
CUL7	4	RANBP2	9	affinity chromatography technology	Hanson D (2014)	1
CDK2	0	CDC5L	2	enzymatic study	Boudrez A (2000)	1
CDK2	0	PRDX1	1	affinity chromatography technology	Neganova I (2011)	1
CCDC22	1	CUL2	3	affinity chromatography technology	Starokadomskyy P (2013)	1
COPS7B	0	COPS7A	0	biochemical, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2017)	2
PRKN	1	LMNA	2	affinity chromatography technology	Zanon A (2013)	1
KCTD3	2	SHKBP1	4	affinity chromatography technology	Huttlin EL (2017)	1
CUL1	7	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	KLHL42	1	affinity chromatography technology	Olma MH (2009)	1
UBE2M	0	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
DCUN1D1	0	UBE2M	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, unspecified method, affinity chromatography technology	Kim AY (2008), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Scott DC (2011), Huang G (2014), Huang G (2014), Keuss MJ (2016), Huttlin EL (2017), Zhou H (2017), Zhou H (2017), Zhou H (2017)	13
UBE2M	0	KBTBD7	3	affinity chromatography technology	Huttlin EL (2017)	1
CUL5	1	BTBD1	2	affinity chromatography technology	Bennett EJ (2010)	1
BTBD1	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	UBE2M	0	affinity chromatography technology	Ewing RM (2007)	1
PAX6	3	UBE2M	0	affinity chromatography technology	Hein MY (2015)	1
KBTBD7	3	RBX1	2	affinity chromatography technology	Genau HM (2015)	1
UBE2M	0	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D2	0	CUL3	17	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	7
ITGA4	4	PCBP1	2	affinity chromatography technology	Byron A (2012)	1
COPS5	0	UBA3	0	genetic interference	Horlbeck MA (2018)	1
ITGA4	4	UBE2M	0	affinity chromatography technology	Byron A (2012)	1
CAND1	2	PCBP1	2	affinity chromatography technology	Bennett EJ (2010)	1
PCBP1	2	PCBP2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical	Lim J (2006), Lim J (2006), Leidgens S (2013), Wan C (2015)	4
UBE2M	0	SAE1	0	biochemical	Wan C (2015)	1
CUL2	3	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	COPS7A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sharon M (2009), Luke-Glaser S (2007), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016)	13
KRAS	1	PINK1	2	genetic interference	Luo J (2009)	1
TP53	0	PCBP1	2	affinity chromatography technology	Fogeron ML (2013)	1
COPS6	0	KLHL42	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
GPS1	1	COPS4	0	affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical	Stotland A (2012), Tsuge T (2001), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015)	7
COPS2	5	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Yang X (2002), Choo YY (2011), Bennett EJ (2010), Huttlin EL (2015), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	7
COPS6	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	9
ITGA4	4	LMNA	2	affinity chromatography technology	Byron A (2012)	1
PCBP1	2	EWSR1	2	two hybrid	Lim J (2006)	1
UBE2M	0	ITCH	1	pull down, pull down	Li H (2016), Li H (2016)	2
ITCH	1	EWSR1	2	pull down	Ingham RJ (2005)	1
UBE2M	0	DCUN1D2	0	pull down, x-ray crystallography, affinity chromatography technology, pull down	Monda JK (2013), Monda JK (2013), Meyer-Schaller N (2009), Keuss MJ (2016)	4
LMNA	2	UBE2M	0	bioid	Roux KJ (2012)	1
DCUN1D1	0	DCUN1D2	0	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	CDC5L	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	KLHL24	1	affinity chromatography technology	Huttlin EL (2017)	1
DLD	1	COPS7B	0	affinity chromatography technology	Malty RH (2017)	1
PCBP1	2	APP	1	pull down	Olah J (2011)	1
UBE2M	0	KCTD6	2	affinity chromatography technology	Huttlin EL (2017)	1
PRKN	1	PRDX1	1	affinity chromatography technology	Zanon A (2013)	1
UBE2M	0	DCUN1D4	0	pull down, pull down	Monda JK (2013), Keuss MJ (2016)	2
CAND1	2	GARS	1	biochemical	Kristensen AR (2012)	1
CUL5	1	KLHL42	1	affinity chromatography technology	Bennett EJ (2010)	1
EWSR1	2	SOD1	0	bioid	Elzi DJ (2014)	1
RNF7	0	CUL1	7	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ohta T (1999), Kawakami T (2001), Tan M (2010), Swaroop M (2001), Huang DT (2009), Kuang P (2016), Zhou W (2017)	7
TP53	0	ITCH	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abedini MR (2008), Saha A (2011), Saha A (2011)	3
SOD1	0	LMNA	2	affinity chromatography technology	Malty RH (2017)	1
ITGA4	4	PCBP2	3	affinity chromatography technology	Byron A (2012)	1
RHOBTB1	0	CUL5	1	two hybrid	Berthold J (2008)	1
NEDD8	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
RHOBTB1	0	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
UBE2M	0	DCUN1D5	0	pull down, affinity chromatography technology, pull down, pull down	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016)	4
UBE2M	0	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	KCTD3	2	affinity chromatography technology	Bennett EJ (2010)	1
FN1	17	EWSR1	2	affinity chromatography technology	Humphries JD (2009)	1
ITGA4	4	EWSR1	2	affinity chromatography technology	Byron A (2012)	1
NAE1	0	GARS	1	pull down, affinity chromatography technology	Mo Z (2016), Mo Z (2016)	2
CAND1	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Kim AY (2008), Zheng J (2002), Zheng J (2002), Liu J (2002), Liu J (2002)	7
CUL5	1	RBX1	2	x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Duda DM (2008), Ohta T (1999), Furukawa M (2002), Tron AE (2012), Tron AE (2012), Yu Y (2004), Huang DT (2009), Wang X (2015), Wang X (2015), Wang X (2015)	10
VCP	6	RNF7	0	affinity chromatography technology	Yu CC (2013)	1
CDK2	0	UBE2T	0	enzymatic study	Lv Z (2017)	1
UBE2M	0	VAMP2	3	biochemical	Havugimana PC (2012)	1
UBE2M	0	NISCH	11	affinity chromatography technology	Huttlin EL (2017)	1
NEDD8	0	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	3
COPS5	0	PCBP1	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	CUL3	17	pull down	Plafker KS (2009)	1
MDM2	2	ITCH	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kubo N (2010), Kubo N (2010), Wu H (2015), Wu H (2015)	4
VCP	6	LMNA	2	affinity chromatography technology	Yu CC (2013)	1
CUL3	17	SNW1	0	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	SAE1	0	biochemical	Kristensen AR (2012)	1
DCUN1D1	0	KLHL42	1	affinity chromatography technology	Bennett EJ (2010)	1
FBXO7	1	UBE2M	0	enzymatic study	Teixeira FR (2016)	1
PINK1	2	PRKN	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Shiba K (2009), Shiba K (2009), Geisler S (2010), Um JW (2009), Um JW (2009), Xiong H (2009), Xiong H (2009), Xiong H (2009), Kondapalli C (2012), Kondapalli C (2012), Sha D (2010), Sha D (2010), Sha D (2010), Sha D (2010), Lazarou M (2013), Zheng X (2013), Fedorowicz MA (2014), Vives-Bauza C (2010), Shiba-Fukushima K (2014), Bertolin G (2015), Fiesel FC (2015), Kazlauskaite A (2015), Moore DJ (2006), Moore DJ (2006), Zhang T (2016), Klosowiak JL (2016), Gersch M (2017)	27
FN1	17	PCBP2	3	affinity chromatography technology	Humphries JD (2009)	1
RBX1	2	CUL7	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Dias DC (2002), Dias DC (2002), Andrews P (2006), Andrews P (2006), Huber C (2005), Huber C (2005), Xu X (2012), Nie J (2015)	9
CUL3	17	PRDX1	1	affinity chromatography technology	Bennett EJ (2010)	1
MEPCE	1	PCBP2	3	affinity chromatography technology	Jeronimo C (2007)	1
COPS7A	0	BTBD1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
COPS6	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
KLHL20	2	CUL3	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Lee YR (2010), Bennett EJ (2010), Yuan WC (2014), Chen HY (2015), Chen HY (2015), Huttlin EL (2017)	6
RNF7	0	CUL2	3	two hybrid, enzymatic study	Ohta T (1999), Huang DT (2009)	2
SOD1	0	SAE1	0	affinity chromatography technology	Malty RH (2017)	1
DCUN1D4	0	CAND1	2	affinity chromatography technology, pull down	Keuss MJ (2016), Keuss MJ (2016)	2
NEDD8	0	SHKBP1	4	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D2	0	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
CUL7	4	EWSR1	2	affinity chromatography technology	Hanson D (2014)	1
TP53	0	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
CUL3	17	EWSR1	2	affinity chromatography technology	Bennett EJ (2010)	1
KBTBD7	3	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Bennett EJ (2010), Genau HM (2015), Genau HM (2015), Huttlin EL (2017)	5
FBXO7	1	PCBP1	2	affinity chromatography technology	Teixeira FR (2016)	1
VCP	6	MDM2	2	affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Okoro DR (2013)	2
TYMS	0	UBE2M	0	biochemical	Havugimana PC (2012)	1
MEPCE	1	CAND1	2	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Bennett EJ (2010)	2
UBE2M	0	BTBD1	2	affinity chromatography technology	Huttlin EL (2017)	1
TERF1	1	PRDX1	1	two hybrid	Lee OH (2011)	1
CUL5	1	CUL2	3	affinity chromatography technology	Bennett EJ (2010)	1
FN1	17	CAND1	2	affinity chromatography technology	Humphries JD (2009)	1
PCBP1	2	SMURF1	4	affinity chromatography technology	Zhang MP (2017)	1
NEDD4	2	CUL1	7	affinity chromatography technology	Liu J (2014)	1
CUL1	7	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Menon S (2008), Chew EH (2007), Min KW (2005), Min KW (2005), Min KW (2005), Hwang JW (2003), Hwang JW (2003), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012), Zheng J (2002), Zheng J (2002), Bornstein G (2006), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), He YJ (2006), Emberley ED (2012), Choo YY (2011), Jonason JH (2007), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Liu J (2002), Liu J (2002), Korzeniewski N (2012), Pierce NW (2013), Kim AY (2008), Zhang S (2016), Tikhmyanova N (2017), Tikhmyanova N (2017), Reitsma JM (2017), Reitsma JM (2017)	41
KRAS	1	SNW1	0	genetic interference	Luo J (2009)	1
FN1	17	DLD	1	affinity chromatography technology	Humphries JD (2009)	1
DCUN1D2	0	APP	1	pull down	Olah J (2011)	1
FBXO7	1	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
DCUN1D1	0	RBX1	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bommelje CC (2013), Meyer-Schaller N (2009), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	9
MDM2	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Iyappan S (2010), Dou H (2012), Brenkman AB (2008), Fang S (2000), Szypowska AA (2011), Okamoto K (2009), Busso CS (2009), Maguire M (2008), Sehat B (2008), Uldrijan S (2007), Yang Y (2005), Jin Y (2004), Roxburgh P (2012), Shloush J (2011), Rinaldo C (2007), Cheng Q (2009), Amson R (2011), Li X (2009), David Y (2011), Sosin AM (2012), Schumacher FR (2013), Bista M (2013), Mikawa T (2014), Lohrum MA (2001), Fang S (2001), Saville MK (2004), Rodriguez MS (1999), Auger KR (2005), Wu PY (2003), Wu H (2015), Yamauchi T (2014), Nomura K (2017), Kurokawa M (2013)	33
CUL7	4	LMNA	2	affinity chromatography technology	Hanson D (2014)	1
PINK1	2	NAE1	0	affinity chromatography technology	Choo YS (2012)	1
DCUN1D1	0	KLHL18	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	RHOBTB1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	3
RNF7	0	CUL5	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, enzymatic study, pull down, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ohta T (1999), Bennett EJ (2010), Tan M (2008), Kelsall IR (2013), Kelsall IR (2013), Zhou W (2014), Rolland T (2014), Huang DT (2009), Kim DY (2013), Kim DY (2013), Yu H (2011), Bulatov E (2015), Wang X (2015), Wang X (2015), Wang X (2015), Kershaw NJ (2014), Huttlin EL (2017), Kuang P (2016), Kuang P (2016), Zhou W (2017), Zhou W (2017)	21
CUL3	17	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Chua YS (2011), Chua YS (2011), Tron AE (2012), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Schumacher FR (2015), Schumacher FR (2015), Lo SC (2006), Lo SC (2006)	12
COPS5	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
FBXO7	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vingill S (2016), Teixeira FR (2016), Teixeira FR (2016)	3
CUL1	7	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	3
COPS5	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
VCAM1	2	PRDX1	1	affinity chromatography technology	Humphries JD (2009)	1
MARCH7	0	UBE2M	0	two hybrid	Flach K (2014)	1
NEDD8	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Wimuttisuk W (2007)	4
COPS5	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Pick E (2012)	7
NEDD8	0	KBTBD7	3	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	KCTD3	2	affinity chromatography technology	Huttlin EL (2017)	1
CUL1	7	CDC5L	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lleres D (2010)	2
COPS5	0	APP	1	pull down, affinity chromatography technology	Olah J (2011), Wang H (2013)	2
NEDD4	2	CUL5	1	affinity chromatography technology	Zhou W (2014)	1
PRKN	1	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down	Joch M (2007), Imai Y (2002), Chaugule VK (2011), Durcan TM (2011), Caulfield TR (2014), Kazlauskaite A (2014)	6
KRAS	1	UBE2M	0	genetic interference	Luo J (2009)	1
DCUN1D1	0	SHKBP1	4	affinity chromatography technology	Bennett EJ (2010)	1