Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
RNF8 rs2284922 A carboplatin efficacy yes When compared to women who received different treatment regimens. Response was defined as likelihood of achieving relapse-free survival. Please note that alleles have been complemented to the positive strand. Allele A is associated with increased response to carboplatin, docetaxel and trastuzumab in women with Breast Neoplasms. 30071039 1449713624