PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
HNF4A	2	MED7	1	pull down	Malik S (2002)	1
TRRAP	31	MED26	2	biochemical	Meyer KD (2008)	1
MED26	2	MED23	3	affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011)	2
UBE2I	0	EP300	36	enzymatic study, affinity chromatography technology	Girdwood D (2003), Bian XL (2017)	2
SREBF1	5	MED12	11	biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	3
MED14	0	MED17	0	affinity chromatography technology, biochemical, biochemical	Ryu S (1999), Havugimana PC (2012), Wan C (2015)	3
CDK8	1	MED1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito M (1999), Kang YK (2002), Zhang X (2005), Donner AJ (2010), Donner AJ (2010), Gu W (1999), Gu W (1999), Malik S (2000), Davis MA (2013), Davis MA (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	14
SREBF1	5	TWIST2	0	two hybrid, pull down	Lee YS (2003), Lee YS (2003)	2
KLF13	3	SREBF2	5	pull down	Natesampillai S (2006)	1
SREBF1	5	RUVBL2	4	affinity chromatography technology	Ebmeier CC (2010)	1
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
UBE2I	0	MED7	1	enzymatic study	Jakobs A (2007)	1
MED21	1	MED24	4	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
TRRAP	31	MED23	3	biochemical	Meyer KD (2008)	1
MED12	11	MED24	4	affinity chromatography technology, biochemical, affinity chromatography technology	Malovannaya A (2010), Havugimana PC (2012), Hein MY (2015)	3
SREBF1	5	KAT2A	1	affinity chromatography technology	Ebmeier CC (2010)	1
MED26	2	MED25	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Mittler G (2003), Takahashi H (2011)	3
MED25	1	MED14	0	affinity chromatography technology	Mittler G (2003)	1
MED1	4	MED24	4	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, genetic interference	Yuan CX (1998), Zhang X (2005), Zhang X (2005), Malovannaya A (2010), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Horlbeck MA (2018)	8
SREBF1	5	MED25	1	affinity chromatography technology, pull down	Taatjes DJ (2002), Yang F (2006)	2
MED25	1	MED17	0	affinity chromatography technology, affinity chromatography technology	Mittler G (2003), Mittler G (2003)	2
MED1	4	MED23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, genetic interference	Zhang X (2005), Malovannaya A (2010), Donner AJ (2010), Lambert JP (2015), Huttlin EL (2017), Horlbeck MA (2018)	6
MED15	6	MED24	4	biochemical	Wan C (2015)	1
SP1	0	HNF4A	2	affinity chromatography technology, affinity chromatography technology, pull down	Wang HY (2009), Wang HY (2009), Magenheim J (2005)	3
TRRAP	31	MED1	4	biochemical	Meyer KD (2008)	1
MED13	11	MED7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai KL (2013), Huttlin EL (2015), Huttlin EL (2017)	3
MED26	2	MED1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Donner AJ (2010), Takahashi H (2011), Takahashi H (2011), Huttlin EL (2017)	5
SREBF1	5	SREBF2	5	fluorescent resonance energy transfe	Zoumi A (2005)	1
TADA2B	3	TRRAP	31	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
KLF5	4	GSK3B	1	affinity chromatography technology, enzymatic study, enzymatic study	Liu N (2010), Zhao D (2010), Liu N (2010)	3
TRIM25	5	MED12	11	affinity chromatography technology	Choudhury NR (2017)	1
KLF5	4	SREBF1	5	affinity chromatography technology	Lee MY (2009)	1
TRIM25	5	HSP90AA1	7	affinity chromatography technology	Choudhury NR (2017)	1
CDK8	1	MED13	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito M (1999), Kang YK (2002), Donner AJ (2010), Malik S (2000), Davis MA (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
PRMT5	3	SREBF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Liu L (2016), Liu L (2016), Liu L (2016), Liu L (2016)	4
MED1	4	AR	3	affinity chromatography technology, pull down	Wang Q (2002), Wang Q (2002)	2
MED7	1	MED21	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAPK1	1	AR	3	pull down	Yeh S (1999)	1
SREBF1	5	PVALB	0	affinity chromatography technology	Huttlin EL (2017)	1
MED6	0	MED23	3	biochemical, bioid	Akoulitchev S (2000), Lambert JP (2015)	2
SREBF1	5	PLK1	0	affinity chromatography technology, pull down	Bengoechea-Alonso MT (2016), Bengoechea-Alonso MT (2016)	2
TRIM25	5	MAPK1	1	affinity chromatography technology	Choudhury NR (2017)	1
MED1	4	5430	0	affinity chromatography technology, affinity chromatography technology	Zhang X (2005), Huttlin EL (2017)	2
MED14	0	MED7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ryu S (1999), Huttlin EL (2015), Huttlin EL (2017)	3
MED12	11	MED6	0	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Malovannaya A (2010), Havugimana PC (2012), Wan C (2015), Hein MY (2015)	4
EP300	36	KLF13	3	enzymatic study	Song CZ (2003)	1
MED6	0	MED14	0	biochemical, biochemical	Sun X (1998), Wan C (2015)	2
CDK8	1	MED17	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito M (1999), Kang YK (2002), Donner AJ (2010), Malik S (2000), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Tsutsui T (2013), Huttlin EL (2017)	9
HNF4A	2	MED21	1	pull down	Malik S (2002)	1
CREBBP	29	SREBF2	5	far western blotting, affinity chromatography technology, affinity chromatography technology	Oliner JD (1996), Oliner JD (1996), Nath S (2014)	3
KAT2A	1	MED17	0	affinity chromatography technology	Liu X (2008)	1
FBXW7	2	MED24	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Davis MA (2013), Kourtis N (2015)	3
MED15	6	MED13	11	affinity chromatography technology	Mittler G (2003)	1
EGF	2	LMNA	2	two hybrid, affinity chromatography technology	Zhong N (2005), Zhong N (2005)	2
MED14	0	MED24	4	affinity chromatography technology, biochemical, biochemical, genetic interference	Ryu S (1999), Havugimana PC (2012), Wan C (2015), Horlbeck MA (2018)	4
SP1	0	AR	3	affinity chromatography technology, affinity chromatography technology	Yuan H (2005), Chen PH (2008)	2
MAPK1	1	CREBBP	29	enzymatic study	Janknecht R (1996)	1
TRRAP	31	MED14	0	biochemical	Meyer KD (2008)	1
SREBF1	5	GCN1	6	affinity chromatography technology	Ebmeier CC (2010)	1
UBE2I	0	ZBTB7A	3	enzymatic study	Roh HE (2007)	1
MED12	11	TADA3	0	affinity chromatography technology	Hein MY (2015)	1
TRIM25	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
TRIM25	5	ZBTB7A	3	affinity chromatography technology	Choudhury NR (2017)	1
5430	0	PRMT5	3	affinity chromatography technology, enzymatic study	Zhao DY (2016), Zhao DY (2016)	2
MED17	0	MED24	4	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
SCAP	2	SREBF1	5	affinity chromatography technology	Sakai J (1997)	1
MED7	1	MED12	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
MED12	11	KAT2A	1	affinity chromatography technology	Hein MY (2015)	1
AR	3	UBE2I	0	two hybrid, affinity chromatography technology, genetic interference, enzymatic study	Poukka H (1999), Poukka H (1999), Poukka H (1999), Ogawa H (2009)	4
ID2	0	PRMT5	3	affinity chromatography technology	Lee SB (2016)	1
CDK8	1	MED14	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang G (2001), Ito M (1999), Donner AJ (2010), Gu W (1999), Gu W (1999), Malik S (2000), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	10
EP300	36	5430	0	affinity chromatography technology, affinity chromatography technology	Cho H (1998), Fousteri M (2006)	2
FBXW7	2	GSK3B	1	affinity chromatography technology	Kwon YW (2012)	1
MAPK1	1	ID2	0	two hybrid	Wang J (2008)	1
MED25	1	MED6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang F (2004), Mittler G (2003), Mittler G (2003), Lee HK (2007)	4
MED15	6	MED14	0	affinity chromatography technology, biochemical	Mittler G (2003), Wan C (2015)	2
PRMT5	3	EP300	36	genetic interference	Wong AS (2016)	1
SREBF1	5	CDK8	1	affinity chromatography technology, pull down	Taatjes DJ (2002), Yang F (2006)	2
SREBF1	5	TRRAP	31	affinity chromatography technology	Ebmeier CC (2010)	1
KLF13	3	CREBBP	29	genetic interference, affinity chromatography technology, affinity chromatography technology, enzymatic study	Song CZ (2002), Song CZ (2002), Song CZ (2002), Song CZ (2002)	4
SREBF1	5	AR	3	affinity chromatography technology, pull down	Suh JH (2008), Suh JH (2008)	2
ATXN1L	0	SREBF1	5	two hybrid	Lim J (2006)	1
ZBTB7A	3	SP1	0	affinity chromatography technology	Laudes M (2008)	1
TRIM25	5	SREBF1	5	affinity chromatography technology	Choudhury NR (2017)	1
KLF13	3	SREBF1	5	pull down	Natesampillai S (2006)	1
SIRT1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Lin Z (2012), Hein MY (2015)	2
UBE2I	0	CREBBP	29	affinity chromatography technology, pull down, enzymatic study, two hybrid	Hsieh YL (2013), Hsieh YL (2013), Hsieh YL (2013), Liu ST (2012)	4
HNF4A	2	SIRT1	3	affinity chromatography technology	Chanda D (2010)	1
HSP90AA1	7	SREBF1	5	affinity chromatography technology	Taipale M (2012)	1
TADA3	0	EP300	36	affinity chromatography technology, affinity chromatography technology	Wang T (2001), Germaniuk-Kurowska A (2007)	2
CDK8	1	MED23	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Wang G (2001), Kang YK (2002), Donner AJ (2010), Boyer TG (1999), Davis MA (2013), Varjosalo M (2013), Huttlin EL (2015), Lambert JP (2015), Hein MY (2015), Huttlin EL (2017)	10
INSIG1	0	SREBF1	5	affinity chromatography technology	Yabe D (2002)	1
MED1	4	MED7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang X (2005), Huttlin EL (2015), Huttlin EL (2017)	3
MTNR1B	1	SREBF1	5	two hybrid	Benleulmi-Chaachoua A (2016)	1
GSK3B	1	SREBF1	5	enzymatic study	Bengoechea-Alonso MT (2009)	1
MED23	3	MED17	0	bioid, affinity chromatography technology	Lambert JP (2015), Lambert JP (2015)	2
MED1	4	MED15	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang X (2005), Malovannaya A (2010), Donner AJ (2010), Mittler G (2003), Wan C (2015), Huttlin EL (2017)	6
ID2	0	YY1	7	affinity chromatography technology	Huttlin EL (2017)	1
MAPK3	4	CREBBP	29	enzymatic study	Tsai LN (2008)	1
SREBF1	5	MED26	2	biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	3
MED7	1	MED24	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ATXN1	2	UBE2I	0	two hybrid	Lim J (2006)	1
MED26	2	MED13	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Tsai KL (2013)	3
5430	0	RUVBL2	4	biochemical, affinity chromatography technology	Havugimana PC (2012), Cloutier P (2017)	2
MED1	4	MED14	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, genetic interference	Zhang X (2005), Malovannaya A (2010), Donner AJ (2010), Ryu S (1999), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017), Horlbeck MA (2018)	8
SREBF2	5	TRRAP	31	affinity chromatography technology, affinity chromatography technology	Li H (2012), Li H (2012)	2
MED23	3	5430	0	bioid	Lambert JP (2015)	1
SREBF1	5	SREBF1	5	fluorescent resonance energy transfe	Zoumi A (2005)	1
MED7	1	MED17	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED7	1	MED23	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GSK3B	1	MED24	4	two hybrid	Vinayagam A (2011)	1
MED1	4	MED6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Zhang X (2005), Zhang X (2005), Malovannaya A (2010), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	6
KLF5	4	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miyamoto S (2003), Matsumura T (2005), Guo P (2009), Guo P (2009), Nagai R (2005)	5
CREBBP	29	CDK8	1	biochemical, affinity chromatography technology	Cho H (1998), Cho H (1998)	2
MED23	3	MED21	1	bioid, affinity chromatography technology	Lambert JP (2015), Huttlin EL (2017)	2
SREBF1	5	MED17	0	affinity chromatography technology, pull down	Taatjes DJ (2002), Yang F (2006)	2
MED12	11	MED15	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Malovannaya A (2010), Mittler G (2003), Hein MY (2015)	3
MED21	1	MED6	0	biochemical, biochemical, biochemical, affinity chromatography technology	Sun X (1998), Sun X (1998), Havugimana PC (2012), Huttlin EL (2017)	4
UBE2I	0	EGF	2	affinity chromatography technology	Ju WN (2009)	1
ATXN1	2	SREBF1	5	two hybrid	Lim J (2006)	1
GSK3B	1	AR	3	pull down, affinity chromatography technology	Wang L (2004), Wang L (2004)	2
MED26	2	MED17	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Takahashi H (2011)	3
MED21	1	MED15	6	affinity chromatography technology	Huttlin EL (2017)	1
MED13	11	MED6	0	biochemical	Wan C (2015)	1
TRIM25	5	YY1	7	affinity chromatography technology	Choudhury NR (2017)	1
TADA2B	3	TADA3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MED1	4	MED25	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Zhang X (2005), Malovannaya A (2010), Mittler G (2003), Lee HK (2007), Lee HK (2007), Huttlin EL (2017)	6
TRRAP	31	MED13	11	biochemical	Meyer KD (2008)	1
MED24	4	MED25	1	biochemical	Wan C (2015)	1
SREBF1	5	TADA3	0	affinity chromatography technology	Ebmeier CC (2010)	1
HNF4A	2	MED14	0	affinity chromatography technology, pull down	Maeda Y (2002), Malik S (2002)	2
MED25	1	CREBBP	29	two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Lee HK (2007), Lee HK (2007), Lee HK (2007), Lee HK (2007)	4
AR	3	NR0B1	2	affinity chromatography technology, affinity chromatography technology	Holter E (2002), Agoulnik IU (2003)	2
SREBF2	5	UBE2I	0	affinity chromatography technology, two hybrid	Hirano Y (2003), Bandyopadhyay S (2010)	2
FBXW7	2	TRIM25	5	two hybrid	Arroyo R (2015)	1
CDK8	1	MED7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kang YK (2002), Malik S (2000), Boyer TG (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	6
CDK8	1	MED24	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Ito M (1999), Kang YK (2002), Gu W (1999), Gu W (1999), Malik S (2000), Davis MA (2013), Varjosalo M (2013), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
MAPK3	4	ID2	0	two hybrid	Wang J (2008)	1
MAPK1	1	HNF4A	2	enzymatic study	Han S (2010)	1
ERLIN2	2	SCAP	2	affinity chromatography technology, affinity chromatography technology	Wang G (2012), Huber MD (2013)	2
TRIM25	5	PLK1	0	affinity chromatography technology	Choudhury NR (2017)	1
ATXN1	2	MED15	6	two hybrid	Lim J (2006)	1
MED26	2	MED7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Huttlin EL (2015), Huttlin EL (2017)	4
FBXW7	2	CDK8	1	affinity chromatography technology	Kourtis N (2015)	1
TADA3	0	TRRAP	31	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
GSK3B	1	HSP90AA1	7	enzymatic study	Muller P (2012)	1
FBXW7	2	MED14	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Davis MA (2013), Kourtis N (2015)	3
MAPK1	1	SP1	0	enzymatic study, enzymatic study	Milanini-Mongiat J (2002), Cramer T (2008)	2
CDK8	1	PRMT5	3	affinity chromatography technology, affinity chromatography technology, pull down	Tsutsui T (2013), Tsutsui T (2013), Tsutsui T (2013)	3
MAPK3	4	SREBF1	5	enzymatic study	Kotzka J (2000)	1
SREBF1	5	ATM	9	affinity chromatography technology	Ebmeier CC (2010)	1
MED1	4	MED21	1	affinity chromatography technology, biochemical, affinity chromatography technology	Zhang X (2005), Havugimana PC (2012), Huttlin EL (2017)	3
MED26	2	5430	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Takahashi H (2011), Takahashi H (2011)	4
TRRAP	31	MED17	0	biochemical	Meyer KD (2008)	1
FBXW7	2	MED15	6	affinity chromatography technology	Davis MA (2013)	1
FBXW7	2	MED17	0	affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Kourtis N (2015)	2
MED25	1	MED7	1	affinity chromatography technology, affinity chromatography technology	Mittler G (2003), Mittler G (2003)	2
FBXW7	2	MED12	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Davis MA (2013), Kourtis N (2015)	3
LMNA	2	INSIG2	0	two hybrid	Dittmer TA (2014)	1
MED12	11	MED25	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Malovannaya A (2010), Mittler G (2003), Hein MY (2015)	3
FBXW7	2	SREBF1	5	affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Sundqvist A (2005), Sundqvist A (2005), Bengoechea-Alonso MT (2009), Welcker M (2013), Liu L (2016), Bengoechea-Alonso MT (2016), Bengoechea-Alonso MT (2016)	7
MED25	1	MED13	11	affinity chromatography technology	Mittler G (2003)	1
MED25	1	CDK8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang F (2004), Mittler G (2003), Mittler G (2003), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
INSIG1	0	ERLIN2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jo Y (2011), Wang G (2012), Huber MD (2013)	3
TRIM25	5	MED26	2	affinity chromatography technology	Choudhury NR (2017)	1
MED12	11	MED13	11	affinity chromatography technology, biochemical, affinity chromatography technology	Malovannaya A (2010), Wan C (2015), Hein MY (2015)	3
SMARCD3	0	SREBF1	5	pull down	Debril MB (2004)	1
TRRAP	31	MED12	11	biochemical	Meyer KD (2008)	1
MED12	11	MED17	0	affinity chromatography technology, biochemical, affinity chromatography technology	Malovannaya A (2010), Wan C (2015), Hein MY (2015)	3
INSIG2	0	SCAP	2	affinity chromatography technology, affinity chromatography technology	Lee JN (2006), Yabe D (2002)	2
MED26	2	MED12	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Takahashi H (2011), Tsai KL (2013)	4
AR	3	ZBTB7A	3	affinity chromatography technology, pull down	Cui J (2011), Cui J (2011)	2
MAPK3	4	MAPK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Wang J (2009), Wang J (2009), Wan C (2015), Hu B (2006)	6
MED15	6	MED7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mittler G (2003), Huttlin EL (2015), Huttlin EL (2017)	3
ZBTB7C	0	SREBF1	5	affinity chromatography technology, imaging technique, two hybrid	Jeon BN (2012), Jeon BN (2012), Jeon BN (2012)	3
MED26	2	MED15	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Mittler G (2003), Takahashi H (2011)	3
HSP90AA1	7	PRMT5	3	affinity chromatography technology	Maloney A (2007)	1
CREBBP	29	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goto T (2006), Leclerc GJ (2010), Chuang JY (2012), Guo W (2014)	4
AR	3	MED24	4	two hybrid	van de Wijngaart DJ (2009)	1
FBXW7	2	MED21	1	affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Kourtis N (2015)	2
MAPK3	4	FBXW7	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ji S (2015), Ji S (2015), Ji S (2015)	3
HNF4A	2	SREBF2	5	pull down	Inoue S (2011)	1
HSP90AA1	7	FBXW7	2	affinity chromatography technology	Taipale M (2012)	1
MED6	0	MED17	0	biochemical	Wan C (2015)	1
SREBF1	5	ID3	0	pull down	Moldes M (1999)	1
MED26	2	MED24	4	affinity chromatography technology	Sato S (2004)	1
CDK8	1	MED15	6	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Donner AJ (2010), Mittler G (2003), Kagey MH (2010), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Tsutsui T (2013), Huttlin EL (2017)	8
MED21	1	CREBBP	29	affinity chromatography technology	Cho H (1998)	1
SREBF1	5	NR0B1	2	pull down, two hybrid	Lopez D (2001), Lopez D (2001)	2
MED23	3	EP300	36	bioid, affinity chromatography technology	Lambert JP (2015), Lambert JP (2015)	2
TADA3	0	AR	3	pull down	Li CW (2010)	1
MED13	11	MED14	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
MED1	4	MED17	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang X (2005), Zhang X (2005), Liu X (2008), Malovannaya A (2010), Donner AJ (2010), Wan C (2015), Huttlin EL (2017)	7
TADA3	0	KAT2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Germaniuk-Kurowska A (2007), Huttlin EL (2015), Wang YL (2008), Huttlin EL (2017)	4
AR	3	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017)	6
ZBTB7A	3	SREBF1	5	affinity chromatography technology, affinity chromatography technology	Choi WI (2008), Choi WI (2008)	2
ATM	9	5430	0	imaging technique, enzymatic study	Fang L (2014), Baskaran R (1997)	2
TRIM25	5	MED13	11	affinity chromatography technology	Choudhury NR (2017)	1
FBXW7	2	MED1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Davis MA (2013), Kourtis N (2015)	3
USF1	0	SREBF1	5	affinity chromatography technology	Wong RH (2009)	1
MED6	0	CDK8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Yang F (2004), Wang G (2001), Ito M (1999), Kang YK (2002), Pavri R (2005), Gu W (1999), Gu W (1999), Malik S (2000), Varjosalo M (2013), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	13
MED26	2	MED21	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Huttlin EL (2017)	3
MED14	0	MED23	3	affinity chromatography technology, biochemical, bioid, affinity chromatography technology	Ryu S (1999), Wan C (2015), Lambert JP (2015), Lambert JP (2015)	4
ERLIN2	2	SREBF1	5	affinity chromatography technology	Huber MD (2013)	1
YY1	7	SREBF1	5	pull down	Bennett MK (1999)	1
PLK1	0	FBXW7	2	affinity chromatography technology, enzymatic study	Xiao D (2016), Xiao D (2016)	2
5430	0	CDK8	1	biochemical, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Cho H (1998), Cho H (1998), Cho H (1998), Pinhero R (2004), Ramanathan Y (2001), Pinhero R (2004), Rovnak J (2012)	7
FBXW7	2	MED23	3	affinity chromatography technology	Davis MA (2013)	1
MED1	4	MED12	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang X (2005), Zhang X (2005), Malovannaya A (2010), Malovannaya A (2010), Donner AJ (2010), Davis MA (2013), Tsai KL (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	10
MED21	1	MED25	1	affinity chromatography technology	Huttlin EL (2017)	1
SREBF1	5	MED24	4	biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	3
SREBF1	5	MED21	1	affinity chromatography technology	Taatjes DJ (2002)	1
MED1	4	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
TRRAP	31	RUVBL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017), Cloutier P (2017)	3
MAPK3	4	HNF4A	2	enzymatic study	Han S (2010)	1
MAPK3	4	SREBF2	5	enzymatic study, enzymatic study	Kotzka J (2000), Kotzka J (2004)	2
MED17	0	MED13	11	biochemical	Wan C (2015)	1
SCAP	2	SREBF2	5	affinity chromatography technology	Sakai J (1997)	1
CREBBP	29	5430	0	biochemical, affinity chromatography technology	Cho H (1998), Cho H (1998)	2
TRRAP	31	MED15	6	biochemical	Meyer KD (2008)	1
MED25	1	MED15	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang F (2004), Mittler G (2003), Mittler G (2003), Mittler G (2003)	4
SREBF2	5	ATXN1	2	two hybrid	Bandyopadhyay S (2010)	1
SREBF1	5	MED15	6	pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down, imaging technique	Naeaer AM (1999), Ebmeier CC (2010), Taatjes DJ (2002), Yang F (2006), Yang F (2006), Yang F (2006), Yang F (2006)	7
SREBF1	5	TADA2B	3	affinity chromatography technology	Ebmeier CC (2010)	1
MED23	3	CREBBP	29	bioid, affinity chromatography technology	Lambert JP (2015), Lambert JP (2015)	2
UBE2I	0	KLF5	4	enzymatic study	Oishi Y (2008)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
MED6	0	MED15	6	affinity chromatography technology, affinity chromatography technology, biochemical	Yang F (2004), Mittler G (2003), Wan C (2015)	3
SREBF1	5	HNF4A	2	pull down, affinity chromatography technology	Ponugoti B (2007), Ponugoti B (2010)	2
EP300	36	SREBF2	5	far western blotting	Oliner JD (1996)	1
EP300	36	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Bouras T (2005), Bourguignon LY (2009)	2
YY1	7	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bennett MK (1999), Li H (2008), Li H (2008), Santiago FS (2007), Qiao H (2011), Lee JS (1993), Lee JS (1993)	7
MAPK1	1	SREBF2	5	enzymatic study, enzymatic study	Kotzka J (2000), Kotzka J (2004)	2
CDK8	1	MED21	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cho H (1998), Sune C (1997), Ito M (1999), Kang YK (2002), Gu W (1999), Malik S (2000), Varjosalo M (2013), Hein MY (2015), Huttlin EL (2017)	9
FBXW7	2	MED13	11	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Davis MA (2013), Davis MA (2013), Loveless TB (2015), Loveless TB (2015), Kourtis N (2015)	6
CREBBP	29	HNF4A	2	two hybrid, affinity chromatography technology, pull down, genetic interference, pull down, pull down, enzymatic study, pull down, affinity chromatography technology	Yoshida E (1997), Yoshida E (1997), Yoshida E (1997), Yoshida E (1997), Dell H (1999), Surapureddi S (2008), Soutoglou E (2000), Soutoglou E (2000), Green VJ (1998)	9
MED6	0	MED7	1	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017)	3
ERLIN2	2	SREBF2	5	affinity chromatography technology	Huber MD (2013)	1
SIRT1	3	SREBF1	5	enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Walker AK (2010), Ponugoti B (2010), Ponugoti B (2010), Ponugoti B (2010), Ponugoti B (2010)	5
KAT2A	1	TRRAP	31	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McMahon SB (2000), Helmlinger D (2006), Meyer KD (2008), Krebs AR (2010), Kim J (2010), Kim J (2010), Liu X (2003)	7
MED21	1	MED14	0	biochemical, biochemical, affinity chromatography technology	Sun X (1998), Havugimana PC (2012), Huttlin EL (2017)	3
MED26	2	MED6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Takahashi H (2011), Takahashi H (2011)	3
TRIM25	5	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
MED15	6	MED17	0	affinity chromatography technology, biochemical	Mittler G (2003), Wan C (2015)	2
HNF4A	2	MED23	3	affinity chromatography technology	Maeda Y (2002)	1
SREBF1	5	EGF	2	affinity chromatography technology	Ju WN (2009)	1
HSP90AA1	7	AR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Veldscholte J (1992), Nemoto T (1992), Zoubeidi A (2007), DaSilva J (2009), Chymkowitch P (2011), Gibbs A (2009), Wolf SS (2007), Luo J (2015), Kwegyir-Afful AK (2015), Ni L (2010), McClurg UL (2016)	11
MED23	3	MED13	11	bioid	Lambert JP (2015)	1
EP300	36	SREBF1	5	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, enzymatic study	Sundqvist A (2003), Giandomenico V (2003), Giandomenico V (2003), Naeaer AM (1999), Naeaer AM (1999), Ebmeier CC (2010), Ponugoti B (2010)	7
MED1	4	KAT2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu X (2008), Liu X (2008), Krebs AR (2010)	3
MED23	3	MED24	4	biochemical, bioid, affinity chromatography technology	Wan C (2015), Lambert JP (2015), Lambert JP (2015)	3
CREBBP	29	AR	3	two hybrid, pull down, pull down, genetic interference, affinity chromatography technology, pull down	Kim J (2005), Fronsdal K (1998), Ishitani K (2003), Aarnisalo P (1998), Andersen RJ (2010), Fronsdal K (1998)	6
YY1	7	CREBBP	29	affinity chromatography technology, affinity chromatography technology	de Nigris F (2007), de Nigris F (2007)	2
LMNA	2	SREBF1	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Lloyd DJ (2002), Lloyd DJ (2002), Lloyd DJ (2002), Ju WN (2009)	4
SREBF1	5	MED14	0	biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	3
ATXN1L	0	ATXN1	2	two hybrid, affinity chromatography technology, two hybrid	Mizutani A (2005), Mizutani A (2005), Lim J (2006)	3
HNF4A	2	MED24	4	pull down	Malik S (2002)	1
INSIG2	0	SREBF1	5	affinity chromatography technology	Yabe D (2002)	1
TRRAP	31	CDK8	1	biochemical	Meyer KD (2008)	1
SREBF1	5	5430	0	affinity chromatography technology	Wan W (2017)	1
SIRT1	3	KAT2A	1	affinity chromatography technology, affinity chromatography technology	Lin Z (2012), Armour SM (2013)	2
MED15	6	MED23	3	affinity chromatography technology, bioid	Mittler G (2003), Lambert JP (2015)	2
INSIG1	0	INSIG2	0	affinity chromatography technology	Lee PC (2010)	1
SREBF1	5	ID2	0	pull down	Moldes M (1999)	1
FBXW7	2	MED6	0	affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Kourtis N (2015)	2
SREBF1	5	MED6	0	biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	3
CREBBP	29	SREBF1	5	far western blotting, affinity chromatography technology, biochemical, pull down, pull down, imaging technique, pull down, pull down, pull down	Oliner JD (1996), Oliner JD (1996), Naeaer AM (1999), Naeaer AM (1999), Naeaer AM (1998), Yang F (2006), Yang F (2006), Yang F (2006), Ericsson J (1998)	9
SREBF1	5	MED1	4	biochemical, imaging technique, pull down	Naeaer AM (1999), Yang F (2006), Yang F (2006)	3
MED12	11	MED23	3	affinity chromatography technology, bioid, affinity chromatography technology	Malovannaya A (2010), Lambert JP (2015), Hein MY (2015)	3
SP1	0	HSP90AA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Hung JJ (2005), Hung JJ (2005), Wang SA (2009), Wang SA (2009)	4
TADA2B	3	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SREBF1	5	UBE2I	0	affinity chromatography technology	Hirano Y (2003)	1
MED1	4	MED13	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang X (2005), Zhang X (2005), Malovannaya A (2010), Donner AJ (2010), Davis MA (2013), Tsai KL (2013), Wan C (2015), Huttlin EL (2017)	8
CDK8	1	MED12	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito M (1999), Kang YK (2002), Donner AJ (2010), Malik S (2000), Kagey MH (2010), Davis MA (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Tsutsui T (2013), Huttlin EL (2017)	12
HNF4A	2	MED17	0	pull down	Malik S (2002)	1
MED26	2	MED14	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Ryu S (1999), Takahashi H (2011)	3
EP300	36	YY1	7	enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yao YL (2001), Lee JS (1995), Lee JS (1995), Lee JS (1995), Lee JS (1995), Kadeppagari RK (2009), Kadeppagari RK (2009), Kadeppagari RK (2009), Sankar N (2008), Sankar N (2008), Sankar N (2008), Wang CC (2007), Wang CC (2007), Galvin KM (1997)	14
USF1	0	TRRAP	31	affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011)	2
EP300	36	MAPK1	1	affinity chromatography technology, enzymatic study, enzymatic study	Chen YJ (2007), Chen YJ (2007), Sang N (2003)	3
ZBTB7A	3	SIRT1	3	affinity chromatography technology	Choi WI (2009)	1
MAPK3	4	SP1	0	enzymatic study, enzymatic study	Milanini-Mongiat J (2002), Cramer T (2008)	2
MAPK1	1	GSK3B	1	affinity chromatography technology, pull down, enzymatic study	Ding Q (2005), Ding Q (2005), Ding Q (2005)	3
5430	0	MED21	1	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Scully R (1997), Cho H (1998), Cho H (1998), Sune C (1997), Huttlin EL (2017)	6
SIRT1	3	AR	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fu M (2006), Fu M (2006), Fu M (2006), Fu M (2006)	4
YY1	7	RUVBL2	4	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu S (2007), Wu S (2007), Wu S (2007), Cai Y (2007), Cai Y (2007), Vella P (2011), Huttlin EL (2017), Hauri S (2016)	8
TRIM25	5	LMNA	2	affinity chromatography technology	Choudhury NR (2017)	1
KLF5	4	CREBBP	29	pull down, two hybrid	Zhang Z (2003), Oishi Y (2008)	2
SREBF1	5	MED7	1	pull down, biochemical, affinity chromatography technology	Naeaer AM (1999), Naeaer AM (1999), Taatjes DJ (2002)	3
MAPK1	1	SREBF1	5	enzymatic study	Kotzka J (2000)	1
TRRAP	31	MED25	1	biochemical	Meyer KD (2008)	1
MTNR1B	1	SREBF2	5	two hybrid	Benleulmi-Chaachoua A (2016)	1
MED12	11	MED14	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Malovannaya A (2010), Tsai KL (2013), Wan C (2015), Hein MY (2015)	4
ATM	9	MED1	4	affinity chromatography technology	Mu JJ (2007)	1
UBE2I	0	KAT2A	1	enzymatic study	Gocke CB (2005)	1
INSIG1	0	SCAP	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dobrosotskaya IY (2003), Lee JN (2008), Lee JN (2006), Yabe D (2002), Zhang Y (2013), Cheng C (2015)	6
MED13	11	MED24	4	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
SREBF1	5	SP1	0	pull down, biochemical	Bennett MK (1999), Naeaer AM (1999)	2
EP300	36	RUVBL2	4	pull down	Karmakar S (2010)	1
SREBF1	5	MED23	3	pull down, biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	4
SREBF1	5	MED13	11	biochemical, affinity chromatography technology, pull down	Naeaer AM (1999), Taatjes DJ (2002), Yang F (2006)	3
UBE2I	0	LMNA	2	two hybrid, affinity chromatography technology, enzymatic study	Zhong N (2005), Zhong N (2005), Matafora V (2009)	3
SP1	0	SREBF2	5	pull down, two hybrid	Gunther M (2000), Bandyopadhyay S (2010)	2
TRIM25	5	KLF5	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao KW (2011), Zhao KW (2011), Dong XY (2012), Choudhury NR (2017)	4
MED26	2	CDK8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sato S (2004), Sato S (2004), Donner AJ (2010), Takahashi H (2011)	4
MED25	1	MED23	3	affinity chromatography technology, biochemical, bioid, affinity chromatography technology	Mittler G (2003), Wan C (2015), Lambert JP (2015), Lambert JP (2015)	4
AR	3	HNF4A	2	imaging technique	Mulholland DJ (2003)	1
SREBF1	5	SORL1	9	affinity chromatography technology	Huttlin EL (2017)	1
MED6	0	MED24	4	biochemical	Wan C (2015)	1
TRRAP	31	MED24	4	biochemical	Meyer KD (2008)	1
FBXW7	2	KLF5	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu N (2010), Liu N (2010), Liu N (2010), Zhao D (2010), Zhao D (2010), Zhao D (2010), Bialkowska AB (2014), Zheng B (2018)	8
HNF4A	2	MED1	4	affinity chromatography technology, pull down, pull down	Maeda Y (2002), Maeda Y (2002), Malik S (2002)	3
MED12	11	MED21	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Malovannaya A (2010), Havugimana PC (2012), Hein MY (2015), Huttlin EL (2017)	4
HNF4A	2	UBE2I	0	two hybrid, enzymatic study	Albers M (2005), Zhou W (2012)	2
SIRT1	3	UBE2I	0	enzymatic study	Hsieh YL (2013)	1
MED17	0	MED21	1	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
USF1	0	EP300	36	affinity chromatography technology	Crusselle-Davis VJ (2007)	1
MED13	11	MED21	1	biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2017)	2
INSIG1	0	SREBF2	5	affinity chromatography technology, affinity chromatography technology	Dobrosotskaya IY (2003), Yang T (2002)	2