Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
SREBF1	rs60282872	CC	atorvastatin	efficacy	no	No association was seen with % change in total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol, ApoAI or ApoB after 4 weeks treatment. Variant described as SREBF1 -36delG, and was genotyped using the ApaI restriction enzyme - this rsID maps to a position where the deletion abolishes the restriction site.	Genotype CC is not associated with response to atorvastatin in people with Hypercholesterolemia as compared to genotypes C/del + del/del.	18435918	982046197
SREBF1	rs60282872	del/del	simvastatin	efficacy	no	No association was found between all three genotypes and response (change in total cholesterol, LDL-cholesterol, trigylcerides). Please note; variant was described as SREBF-1a -36del>G, no rsID provided, and was genotyped using ApaI restriction enzyme digest - the deletion abolishes enzyme site. This rsID maps to NM_004176.4:c.-34delG, which maps to an ApaI site which is abolished by the deletion. Allele G is complemented here to allele C for the plus chromosomal strand.	Genotype del/del is not associated with response to simvastatin in people with Hypercholesterolemia as compared to genotype CC.	16158080	982046189