PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SIRT7	1	APP	1	pull down	Olah J (2011)	1
TUBA1A	13	TUBB	3	biochemical, biochemical, pull down	Havugimana PC (2012), Kristensen AR (2012), Wang W (2014)	3
ESR1	0	TUBA1A	13	affinity chromatography technology	Azuma K (2004)	1
SMTNL2	3	CDK2	0	affinity chromatography technology	Huttlin EL (2017)	1
MCM2	3	TUBA1A	13	affinity chromatography technology	Drissi R (2015)	1
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
S100A8	0	ERG28	0	two hybrid	Stelzl U (2005)	1
TRAF3IP1	3	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
COPS5	0	ESR1	0	affinity chromatography technology	Callige M (2005)	1
CYLD	2	TUBA1A	13	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Gao J (2008), Gao J (2008), Gao J (2008), Gao J (2008)	4
ZNF598	6	PPM1B	2	affinity chromatography technology	Garzia A (2017)	1
S100A9	0	NCF2	0	pull down	Kerkhoff C (2005)	1
TRIM25	5	PPIA	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
NUAK1	2	S100A8	0	affinity chromatography technology	Ewing RM (2007)	1
TERF1	1	MCM2	3	two hybrid	Lee OH (2011)	1
TUBA1A	13	S100A8	0	pull down	Vogl T (2004)	1
S100A8	0	PPIA	0	two hybrid	Stelzl U (2005)	1
TP53	0	PRMT1	3	pull down	An W (2004)	1
COPS5	0	S100A8	0	affinity chromatography technology	Bennett EJ (2010)	1
PPM1B	2	LRRK1	12	biochemical	Wan C (2015)	1
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
USF2	3	S100A8	0	affinity chromatography technology	Ewing RM (2007)	1
SIRT7	1	MCM5	1	affinity chromatography technology	Tsai YC (2012)	1
CFTR	5	PPP2R2A	0	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Pankow S (2015)	2
PTEN	24	S100A9	0	pull down	Verrastro I (2015)	1
CFTR	5	BAG3	4	affinity chromatography technology	Pankow S (2015)	1
TRIM25	5	PRMT1	3	affinity chromatography technology	Choudhury NR (2017)	1
NF2	1	S100A9	0	affinity chromatography technology	Zhou L (2015)	1
APP	1	PAXIP1	1	two hybrid	Soler-Lopez M (2011)	1
CDKN1A	1	GDF9	2	two hybrid	Vinayagam A (2011)	1
TP53	0	CYLD	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016)	4
COPS5	0	S100A9	0	affinity chromatography technology	Bennett EJ (2010)	1
SIRT6	2	TRIM25	5	affinity chromatography technology	Simeoni F (2013)	1
TBC1D22B	2	S100A9	0	affinity chromatography technology	Huttlin EL (2017)	1
ZNF598	6	TUBB	3	affinity chromatography technology	Garzia A (2017)	1
CDKN1A	1	TUBB	3	affinity chromatography technology	Fogeron ML (2013)	1
S100A8	0	CHGB	3	two hybrid	Stelzl U (2005)	1
SLX1B	0	S100A8	0	affinity chromatography technology	Svendsen JM (2009)	1
CHGB	3	APP	1	pull down	Olah J (2011)	1
BAG3	4	MCM5	1	affinity chromatography technology	Chen Y (2013)	1
BAG3	4	S100A8	0	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
SIRT7	1	DLD	1	affinity chromatography technology	Tsai YC (2012)	1
SHC1	0	APP	1	pull down, affinity chromatography technology	Tarr PE (2002), Tarr PE (2002)	2
MCM2	3	TRIM25	5	affinity chromatography technology	Drissi R (2015)	1
SHC1	0	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
COPS5	0	TUBB	3	affinity chromatography technology	Bennett EJ (2010)	1
PRMT1	3	LRIF1	3	two hybrid	Stelzl U (2005)	1
TRIM25	5	DMWD	3	affinity chromatography technology	Choudhury NR (2017)	1
CYLD	2	PPM1B	2	affinity chromatography technology	Elliott PR (2016)	1
TERF2	2	S100A8	0	affinity chromatography technology	Giannone RJ (2010)	1
GRB2	2	PPP2R2A	0	affinity chromatography technology	Bisson N (2011)	1
LRRK1	12	SHC1	0	affinity chromatography technology	Titz B (2010)	1
PTEN	24	S100A8	0	pull down	Verrastro I (2015)	1
PRMT1	3	TERF1	1	affinity chromatography technology	Mitchell TR (2009)	1
CDKN1A	1	LRIF1	3	two hybrid	Vinayagam A (2011)	1
S100A8	0	PRMT1	3	two hybrid	Stelzl U (2005)	1
CYLD	2	NF2	1	affinity chromatography technology	Elliott PR (2016)	1
BECN1	2	TP53	0	affinity chromatography technology	Verma N (2017)	1
S100A8	0	APP	1	pull down	Olah J (2011)	1
CCNYL1	0	S100A8	0	affinity chromatography technology	Huttlin EL (2017)	1
SHC1	0	TUBA1A	13	affinity chromatography technology	Brehme M (2009)	1
PRMT1	3	TERF2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Mitchell TR (2009), Mitchell TR (2009), Mitchell TR (2009)	3
PPIA	0	APP	1	pull down	Olah J (2011)	1
TP53	0	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
TRIM25	5	S100A8	0	affinity chromatography technology	Choudhury NR (2017)	1
CDK2	0	PRMT1	3	affinity chromatography technology	Neganova I (2011)	1
USF2	3	S100A9	0	affinity chromatography technology	Ewing RM (2007)	1
CDK2	0	S100A8	0	affinity chromatography technology	Neganova I (2011)	1
ESR1	0	TUBB	3	pull down	Nalvarte I (2010)	1
PTEN	24	CHGB	3	two hybrid	Stelzl U (2005)	1
S100A8	0	GDF9	2	two hybrid	Stelzl U (2005)	1
SIRT7	1	COPS5	0	affinity chromatography technology	Mo Y (2017)	1
COPS5	0	CDK2	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Chun Y (2013)	2
CDKN1A	1	S100A8	0	two hybrid	Vinayagam A (2011)	1
MOB1A	2	S100A8	0	affinity chromatography technology	Ewing RM (2007)	1
S100A8	0	PDCD11	5	two hybrid	Stelzl U (2005)	1
ASB3	0	S100A8	0	affinity chromatography technology	Ewing RM (2007)	1
PPP2R2A	0	S100A8	0	affinity chromatography technology	Yadav L (2017)	1
MCM2	3	S100A8	0	affinity chromatography technology	Drissi R (2015)	1
S100A8	0	EFHD1	1	affinity chromatography technology	Huttlin EL (2017)	1
S100A8	0	NCF2	0	pull down	Kerkhoff C (2005)	1
TUBB	3	S100A8	0	pull down	Vogl T (2004)	1
PAXIP1	1	PPIA	0	two hybrid	Woods NT (2012)	1
TFAP4	3	TERF2	2	affinity chromatography technology	Ku WC (2009)	1
SIRT7	1	TP53	0	affinity chromatography technology	Tsai YC (2012)	1
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
NF2	1	S100A8	0	affinity chromatography technology	Zhou L (2015)	1
SIRT6	2	TUBA1A	13	affinity chromatography technology	Simeoni F (2013)	1
TUBGCP3	1	TUBB	3	affinity chromatography technology	Fogeron ML (2013)	1
S100A8	0	S100A8	0	x-ray crystallography, affinity chromatography technology	Ishikawa K (2000), Eremenko E (2013)	2
ESR1	0	PPIA	0	affinity chromatography technology	Kanaujiya JK (2013)	1
CFTR	5	TP53	0	affinity chromatography technology	Pankow S (2015)	1
MCM2	3	S100A9	0	affinity chromatography technology	Drissi R (2015)	1
NUAK1	2	S100A9	0	affinity chromatography technology	Ewing RM (2007)	1
CDK2	0	ESR1	0	enzymatic study, affinity chromatography technology	Zhou W (2014), Zhou W (2014)	2
CDK2	0	MCM2	3	enzymatic study, affinity chromatography technology	Montagnoli A (2006), Neganova I (2011)	2
SIRT6	2	S100A9	0	affinity chromatography technology	Simeoni F (2013)	1
TUBGCP3	1	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
SHC1	0	S100A8	0	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
TFAP4	3	USF2	3	affinity chromatography technology, affinity chromatography technology	Ku WC (2009), Ku WC (2009)	2
MCM5	1	APP	1	pull down	Olah J (2011)	1
TFAP4	3	S100A8	0	affinity chromatography technology	Ku WC (2009)	1
TFAP4	3	TP53	0	affinity chromatography technology	Ku WC (2009)	1
ZNF598	6	PPIA	0	affinity chromatography technology	Garzia A (2017)	1
SMTNL2	3	APP	1	pull down	Olah J (2011)	1
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
GRB2	2	S100A8	0	affinity chromatography technology	Li J (2013)	1
TERF1	1	S100A8	0	affinity chromatography technology	Giannone RJ (2010)	1
PAXIP1	1	PDCD11	5	affinity chromatography technology	Woods NT (2012)	1
S100A8	0	DPH6	2	affinity chromatography technology	Huttlin EL (2017)	1
BECN1	2	S100A8	0	affinity chromatography technology, affinity chromatography technology	Yang L (2012), Yang L (2012)	2
PPP2R2A	0	S100A9	0	affinity chromatography technology	Yadav L (2017)	1
PPM1B	2	S100A8	0	affinity chromatography technology	Ewing RM (2007)	1
TP53	0	TUBB	3	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Horikawa I (2014)	2
BAG3	4	GRB2	2	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
CFTR	5	MCM2	3	affinity chromatography technology	Pankow S (2015)	1
LRRK1	12	GRB2	2	affinity chromatography technology, affinity chromatography technology	Titz B (2010), Brehme M (2009)	2
TRIM25	5	ESR1	0	affinity chromatography technology, pull down, enzymatic study	Nakajima A (2007), Nakajima A (2007), Nakajima A (2007)	3
CYLD	2	S100A9	0	affinity chromatography technology	Elliott PR (2016)	1
SIRT7	1	PDCD11	5	affinity chromatography technology	Tsai YC (2012)	1
ZNF598	6	S100A9	0	affinity chromatography technology	Garzia A (2017)	1
DLD	1	S100A8	0	affinity chromatography technology	Malty RH (2017)	1
PTEN	24	TUBB	3	pull down	Verrastro I (2015)	1
S100A8	0	LRIF1	3	two hybrid	Stelzl U (2005)	1
UBASH3B	4	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
SIRT7	1	S100A8	0	affinity chromatography technology	Tsai YC (2012)	1
CFTR	5	S100A8	0	affinity chromatography technology	Pankow S (2015)	1
CYLD	2	MCM5	1	affinity chromatography technology	Elliott PR (2016)	1
LRRK1	12	S100A8	0	affinity chromatography technology	Ewing RM (2007)	1
S100A8	0	UNC119	4	two hybrid	Stelzl U (2005)	1
S100A9	0	S100A8	0	two hybrid, pull down	Bandyopadhyay S (2010), Vogl T (2004)	2
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
DMWD	3	S100A8	0	affinity chromatography technology	Sowa ME (2009)	1
S100A8	0	SMTNL2	3	affinity chromatography technology	Huttlin EL (2017)	1
ZNF598	6	S100A8	0	affinity chromatography technology	Garzia A (2017)	1
GRB2	2	S100A9	0	affinity chromatography technology	Li J (2013)	1
TRIM25	5	GRB2	2	affinity chromatography technology	Choudhury NR (2017)	1
MCM2	3	APP	1	pull down	Olah J (2011)	1
TRIM25	5	S100A9	0	affinity chromatography technology	Choudhury NR (2017)	1
CDKN1A	1	UNC119	4	two hybrid	Vinayagam A (2011)	1
PTEN	24	ESR1	0	pull down	Lin HK (2004)	1
CYLD	2	S100A8	0	affinity chromatography technology	Elliott PR (2016)	1
MCM2	3	PRMT1	3	affinity chromatography technology	Drissi R (2015)	1
CDKN1A	1	APP	1	pull down	Olah J (2011)	1
ESR1	0	S100A8	0	affinity chromatography technology	Tarallo R (2011)	1
POT1	2	S100A8	0	affinity chromatography technology	Giannone RJ (2010)	1
TERF2	2	POT1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Giannone RJ (2010), Giannone RJ (2010), Liu D (2004), Liu D (2004), Liu D (2004), Hein MY (2015), Huttlin EL (2017)	7
SHC1	0	S100A9	0	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
CDKN1A	1	CHGB	3	two hybrid	Vinayagam A (2011)	1
MCM2	3	SMTNL2	3	affinity chromatography technology	Drissi R (2015)	1
TERF2	2	BAG3	4	affinity chromatography technology	Giannone RJ (2010)	1
PRMT1	3	ESR1	0	pull down	Koh SS (2001)	1
TRAF3IP1	3	TUBB	3	affinity chromatography technology	Guo CW (2010)	1
UBASH3B	4	S100A8	0	affinity chromatography technology	Li J (2013)	1
CYLD	2	TUBB	3	affinity chromatography technology	Elliott PR (2016)	1
TERF1	1	BAG3	4	affinity chromatography technology	Giannone RJ (2010)	1
POT1	2	TERF1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loayza D (2003), Giannone RJ (2010), Giannone RJ (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
CDK2	0	PPIA	0	affinity chromatography technology	Neganova I (2011)	1
S100A8	0	TP53	0	two hybrid	Stelzl U (2005)	1
MCM5	1	TUBB	3	affinity chromatography technology	Drissi R (2015)	1
CYLD	2	PRMT1	3	affinity chromatography technology	Elliott PR (2016)	1
TBC1D22B	2	S100A8	0	affinity chromatography technology	Huttlin EL (2017)	1
GRB2	2	CYLD	2	affinity chromatography technology	Huttlin EL (2017)	1
ASB3	0	S100A9	0	affinity chromatography technology	Ewing RM (2007)	1
CDKN1A	1	TUBA1A	13	two hybrid, affinity chromatography technology	Vinayagam A (2011), Fogeron ML (2013)	2
TP53	0	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
TRAF3IP1	3	S100A8	0	affinity chromatography technology	Guo CW (2010)	1
COPS5	0	PPIA	0	affinity chromatography technology	Bennett EJ (2010)	1
TUBA1A	13	S100A9	0	pull down	Vogl T (2004)	1
TERF2	2	TERF1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Giannone RJ (2010), Ye JZ (2004), Ye JZ (2004)	3
MOB1A	2	APP	1	pull down	Olah J (2011)	1
MCM2	3	TUBB	3	affinity chromatography technology	Drissi R (2015)	1
MCM2	3	GRB2	2	affinity chromatography technology	Drissi R (2015)	1
MCM5	1	S100A9	0	affinity chromatography technology	Drissi R (2015)	1
TUBB	3	S100A9	0	pull down	Vogl T (2004)	1
MCM2	3	PPP2R2A	0	affinity chromatography technology	Drissi R (2015)	1
SHC1	0	UBASH3B	4	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
NUAK1	2	APP	1	pull down	Olah J (2011)	1
BECN1	2	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TUBB	3	APP	1	pull down	Olah J (2011)	1
S100A8	0	IGSF21	1	two hybrid	Stelzl U (2005)	1
MCM5	1	MCM2	3	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), DaFonseca CJ (2001), Havugimana PC (2012), Ramachandran N (2004), Wan C (2015), Drissi R (2015), Drissi R (2015), Huang J (2013), Lossaint G (2013)	10
LRIF1	3	ESR1	0	pull down	Li HJ (2007)	1
GRB2	2	TUBB	3	affinity chromatography technology	Brehme M (2009)	1
PPM1B	2	CDK2	0	enzymatic study, biochemical	Cheng A (2000), Cheng A (2000)	2
TUBGCP3	1	S100A8	0	affinity chromatography technology	Fogeron ML (2013)	1
MCM2	3	PPIA	0	affinity chromatography technology	Drissi R (2015)	1
TRIM25	5	ZNF598	6	affinity chromatography technology	Choudhury NR (2017)	1
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
SIRT6	2	S100A8	0	affinity chromatography technology	Simeoni F (2013)	1
MCM5	1	S100A8	0	affinity chromatography technology	Drissi R (2015)	1
TRIM25	5	UBASH3B	4	affinity chromatography technology	Choudhury NR (2017)	1
POT1	2	BAG3	4	two hybrid	Lee OH (2011)	1
ESR1	0	CDKN1A	1	pull down, pull down, pull down, affinity chromatography technology	Fritah A (2005), Maynadier M (2008), Maynadier M (2008), Kinyamu HK (2003)	4
CFTR	5	S100A9	0	affinity chromatography technology	Wang X (2006)	1
PTEN	24	TUBA1A	13	genetic interference	Vizeacoumar FJ (2013)	1
UBASH3B	4	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), Li J (2013), Li J (2013)	3
PAXIP1	1	S100A8	0	affinity chromatography technology	Woods NT (2012)	1
SHC1	0	ESR1	0	affinity chromatography technology, pull down	Song RX (2002), Song RX (2002)	2
COPS5	0	APP	1	pull down, affinity chromatography technology	Olah J (2011), Wang H (2013)	2
PRMT1	3	IGSF21	1	two hybrid	Stelzl U (2005)	1