Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
ATG16L1	rs10210302	CT + TT	adalimumab	efficacy	yes	After 4 and 12 weeks of treatment, a greater percentage of those with the CT or TT genotype had biological response to treatment as compared to those with the CC genotype. Biological response assessed using change in C-reactive protein (CRP). This association remained significant after correction for multiple testing (p=0.027). Significant results were also seen after 20 and 30 weeks of treatment (p=0.00405), but this was not significant after correction for multiple testing (p=0.134).	Genotypes CT + TT is associated with increased response to adalimumab in people with Crohn Disease as compared to genotype CC.	25712183	1444936434