PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
FYN	1	SYK	3	affinity chromatography technology, pull down	Deckert M (1998), Deckert M (1998)	2
ERBB2	6	JAK2	1	affinity chromatography technology	Ren Z (2002)	1
KIT	4	PIK3R1	6	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	De Sepulveda P (1999), van Dijk TB (2000), Serve H (1994), Zhu MJ (2007), Zhu MJ (2007), Yokouchi M (1997), Chen TC (2014)	7
PIK3CA	8	ARAF	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TNIP1	1	PIK3CD	4	affinity chromatography technology	Wang HB (2007)	1
SRC	2	GAB2	3	affinity chromatography technology	Zhao C (1999)	1
JAK2	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Olayioye MA (1999), Olayioye MA (1999), Jones RB (2006), He K (2013)	4
PTK2	2	JAK2	1	affinity chromatography technology, affinity chromatography technology	Zhu T (1998), Ryu H (2000)	2
CRK	0	FGFR1	2	imaging technique, affinity chromatography technology, pull down	Chen TC (2014), Larsson H (1999), Larsson H (1999)	3
NTRK1	1	EZR	8	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	APPL1	1	unspecified method	Jones RB (2006)	1
PLCG2	11	GAB2	3	affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002)	2
PIK3R1	6	KBTBD2	1	affinity chromatography technology, affinity chromatography technology, pull down	Zhang Z (2016), Zhang Z (2016), Zhang Z (2016)	3
DOK1	2	SRC	2	pull down, unspecified method	van Dijk TB (2000), Liu BA (2012)	2
CBL	7	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka Y (2008), Tanaka Y (2008), Hoff H (2007), Chernock RD (2001), Chernock RD (2001)	5
NTRK1	1	EPN1	4	affinity chromatography technology	Emdal KB (2015)	1
KIT	4	PIK3R2	3	two hybrid	De Sepulveda P (1999)	1
SH3KBP1	1	INPPL1	6	affinity chromatography technology	Havrylov S (2009)	1
PIK3CD	4	PIK3R1	6	pull down, affinity chromatography technology, affinity chromatography technology	Vanhaesebroeck B (1997), Vanhaesebroeck B (1997), Hein MY (2015)	3
PIK3R2	3	PIK3CA	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Kuchay S (2013), Hein MY (2015)	3
NCK1	0	GAB2	3	pull down	Zhao C (1999)	1
FER	1	DNM2	2	biochemical	Kim L (1998)	1
RNF19B	0	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
FASLG	0	PIK3R1	6	imaging technique	Chen TC (2014)	1
CTNNB1	30	EZR	8	affinity chromatography technology	Hiscox S (1999)	1
PIK3R1	6	IRS1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology	Hadari YR (1992), Morrison KB (2002), Gual P (2003), Hamer I (2002), Bazuine M (2003), Tzatsos A (2006), Calegari VC (2005), Tzatsos A (2009), Liu BA (2012), Sung CK (1994), Ren W (2013), Sung CK (1998), Grossmann A (2015), Grossmann A (2015), Antonetti DA (1996), Luo M (2007), Luo M (2007)	17
AKT1	1	ERBB3	3	affinity chromatography technology	Kim CK (2011)	1
IL6ST	0	PTPN6	0	affinity chromatography technology	Bartoe JL (2000)	1
EZR	8	TNFRSF1A	3	biochemical	Gajate C (2005)	1
IRS4	2	PIK3CA	8	affinity chromatography technology	Sano H (2002)	1
SH3KBP1	1	PDGFRB	8	affinity chromatography technology	Szymkiewicz I (2002)	1
CBLB	3	VAV1	2	affinity chromatography technology, two hybrid, pull down, far western blotting, affinity chromatography technology	Sattler M (2002), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997), Bustelo XR (1997)	5
FGFR1	2	SHC1	0	pull down, affinity chromatography technology	Klint P (1995), Vecchione A (2007)	2
BCR	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Million RP (2000), Million RP (2004), Million RP (2004), Puil L (1994), Puil L (1994), Ma G (1997), Maru Y (1995), Maru Y (1995), Gaston I (2004), Gaston I (2004), Brehme M (2009), Bisson N (2011), Huttlin EL (2017)	13
IFNAR1	4	STAT3	0	affinity chromatography technology	Yang CH (1996)	1
LCK	0	SYK	3	affinity chromatography technology, pull down, two hybrid	Thome M (1995), Thome M (1995), Moon KD (2005)	3
PIK3R1	6	PIK3CA	8	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Woscholski R (1994), Chamberlain MD (2004), Ren SY (2005), Kamal M (2010), Sun M (2010), Hein MY (2015), Fang D (2001), Xiong Y (2009), Ivanov AA (2017)	9
SRC	2	EPOR	3	affinity chromatography technology	Liang K (2010)	1
PDGFRA	3	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
ERBB2	6	CRK	0	unspecified method	Jones RB (2006)	1
NTRK1	1	EPHA2	3	affinity chromatography technology	Emdal KB (2015)	1
GAB2	3	AKT1	1	affinity chromatography technology, enzymatic study	Lynch DK (2002), Lynch DK (2002)	2
SYK	3	INPP5D	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012), de Castro RO (2012)	3
IRS1	7	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Zhang J (2007), Froejdoe S (2011)	2
ERBB2	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Vogel W (1996)	5
SHC1	0	EPOR	3	affinity chromatography technology	Damen JE (1993)	1
PIK3R2	3	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Martelli MP (2001)	3
NTRK1	1	PDGFRB	8	affinity chromatography technology	Emdal KB (2015)	1
TGFBR2	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Krymskaya VP (1997), Huttlin EL (2015), Huttlin EL (2017)	3
AGAP2	14	PIK3R1	6	pull down, affinity chromatography technology	Ye K (2000), Ye K (2000)	2
CBL	7	NCK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Erdreich-Epstein A (1999), Miyoshi-Akiyama T (2001), Izadi KD (1998), Izadi KD (1998), Wunderlich L (1999), Shishido T (2000), Okabe S (2006), Adler CE (2000), Adler CE (2000), Buvall L (2013), Buvall L (2013), Buvall L (2013), Buvall L (2013)	13
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
PTTG1	0	PIK3CA	8	affinity chromatography technology	Chamaon K (2005)	1
PIK3R2	3	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
MAPT	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Souter S (2009), Souter S (2009), Souter S (2009)	3
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
SOS1	5	ABL1	9	affinity chromatography technology	Puil L (1994)	1
NLGN3	3	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
SHB	4	ABL1	9	affinity chromatography technology, affinity chromatography technology, pull down	Haegerkvist R (2007), Haegerkvist R (2007), Haegerkvist R (2007)	3
PIK3CB	2	GAB2	3	affinity chromatography technology	Momose H (2003)	1
CD3E	0	LCK	0	affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003)	2
PIK3R1	6	ARHGAP1	0	pull down	Barfod ET (1993)	1
SRC	2	WAS	0	affinity chromatography technology, pull down, pull down	Banin S (1996), Banin S (1996), Finan PM (1996)	3
SYN1	1	SRC	2	affinity chromatography technology	Onofri F (2000)	1
GRB2	2	KHDRBS1	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, two hybrid	Liu SK (1998), Oneyama C (2002), Shen Z (1999), Shen Z (1999), Bandyopadhyay S (2010), Asbach B (2012), Bisson N (2011), Wang J (2011)	8
TNFRSF1A	3	SYK	3	affinity chromatography technology	Lee CK (2015)	1
EGFR	5	AKT1	1	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
CTNNB1	30	SRC	2	affinity chromatography technology	Xi Y (2013)	1
NTRK1	1	IRS2	6	affinity chromatography technology	Emdal KB (2015)	1
ERBB3	3	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology	Schulze WX (2006), Jones RB (2006), Li J (2013)	3
TGFBR1	2	PIK3R1	6	affinity chromatography technology	Krymskaya VP (1997)	1
EPN1	4	ERBB3	3	affinity chromatography technology	Szymanska M (2016)	1
IL6ST	0	STAT3	0	affinity chromatography technology	Novotny-Diermayr V (2002)	1
CSF1R	0	KIT	4	affinity chromatography technology, enzymatic study	Tsujimura T (1999), Tsujimura T (1999)	2
ERBB2	6	DOK1	2	unspecified method	Jones RB (2006)	1
PIK3R1	6	FGFR2	6	affinity chromatography technology	Dufour C (2008)	1
STAT3	0	LCK	0	two hybrid	Grossmann A (2015)	1
VHL	0	NCL	1	pull down	Lai Y (2012)	1
SHB	4	LAT	0	affinity chromatography technology, affinity chromatography technology	Lindholm CK (1999), Lindholm CK (2002)	2
MAP3K5	1	EP300	36	two hybrid	Bandyopadhyay S (2010)	1
PCBP1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SRC	2	BCAR1	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Burnham MR (1999), Burnham MR (1999), Wei L (2002), Hsia DA (2003), Kovacic-Milivojevic B (2001), Donaldson JC (2000), Angers-Loustau A (1999), Cabodi S (2004), Modzelewska K (2006), Sawada Y (2006), Riggins RB (2006), Riggins RB (2006)	12
FGFR2	6	FGFR1	2	affinity chromatography technology	Huttlin EL (2017)	1
PIK3R1	6	DAB2IP	3	pull down, affinity chromatography technology, affinity chromatography technology	Xie D (2009), Xie D (2009), Xie D (2009)	3
SHC1	0	DNM2	2	affinity chromatography technology	Brehme M (2009)	1
PLCG2	11	SYK	3	affinity chromatography technology	Guo B (2000)	1
GRB10	4	JAK2	1	affinity chromatography technology	Moutoussamy S (1998)	1
BCR	3	WEE1	2	affinity chromatography technology	Boldt K (2016)	1
CRK	0	GAB1	3	affinity chromatography technology	Brehme M (2009)	1
EP300	36	ACTA1	1	affinity chromatography technology	Jung SY (2005)	1
VSIG4	1	PIK3R3	0	affinity chromatography technology	Huttlin EL (2015)	1
NLGN3	3	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
CBL	7	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Lin H (2001), Hartley D (1995), Feshchenko EA (2004), Alcazar I (2009), Brehme M (2009), Brehme M (2009), Grossmann A (2015)	7
SRC	2	PDGFRB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee CW (2007), Collin G (2007), Wu CY (2008)	3
ERBB3	3	PIK3CB	2	affinity chromatography technology	Li J (2013)	1
PTGER3	2	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NPM1	0	SQSTM1	0	affinity chromatography technology	Chen R (2013)	1
CRKL	1	PXN	1	affinity chromatography technology, pull down, affinity chromatography technology	Salgia R (1995), Salgia R (1995), Nishiya N (2001)	3
ACTA1	1	SRC	2	affinity chromatography technology	Kim JH (2013)	1
RIPK4	0	IRS4	2	affinity chromatography technology	Rodriguez J (2016)	1
ERBB2	6	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Scaltriti M (2009), Graus-Porta D (1997), Le XF (2005), Chen TC (2014), Ritch PS (2005)	5
LCK	0	FAS	2	pull down	Schlottmann KE (1996)	1
SH3KBP1	1	ABL1	9	affinity chromatography technology	Havrylov S (2009)	1
TMEM17	0	IRS4	2	bioid	Gupta GD (2015)	1
ESR1	0	PIK3R2	3	affinity chromatography technology	Cabodi S (2004)	1
ARHGAP17	1	LCK	0	pull down	Richnau N (2001)	1
EPN1	4	BCAR1	6	biochemical	Kristensen AR (2012)	1
PIK3R2	3	SQSTM1	0	affinity chromatography technology	Sung CK (1998)	1
VAV1	2	LCP2	0	affinity chromatography technology, pull down, affinity chromatography technology	Raab M (1997), Onodera H (1996), Shen M (2009)	3
HAVCR2	0	PIK3R3	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL3	17	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Zhang Z (2016)	2
ESR1	0	KHDRBS1	1	affinity chromatography technology	Tarallo R (2011)	1
YWHAG	5	PIK3R1	6	affinity chromatography technology	Jin J (2004)	1
ERBB2	6	STAT3	0	affinity chromatography technology, unspecified method	Ren Z (2002), Jones RB (2006)	2
IRS4	2	PIK3R3	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
FLT3	5	VHL	0	genetic interference	Shen JP (2017)	1
EGFR	5	NPM1	0	affinity chromatography technology	Liccardi G (2014)	1
PDGFRA	3	VHL	0	genetic interference	Shen JP (2017)	1
PXN	1	PIK3R1	6	imaging technique	Chen TC (2014)	1
PTPN6	0	PLCG2	11	affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016)	2
CBL	7	ABL1	9	affinity chromatography technology, enzymatic study, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, far western blotting, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Soubeyran P (2003), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Miyoshi-Akiyama T (2001), Patel H (2006), Johnson KJ (2009), Shishido T (2000), Shishido T (2000), Shishido T (2000), Gaston I (2004), Jain SK (1997), Reedquist KA (1996), Bhat A (1997), Bhat A (1997), Bhat A (1997), Grossmann AH (2004), Brehme M (2009), Brehme M (2009), Brehme M (2009), Nishihara T (2003), Tsukahara F (2010)	21
BCR	3	ABL1	9	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Ling X (2003), Pendergast AM (1991), Puil L (1994), Puil L (1994), Slupianek A (2011)	5
CTNNB1	30	SIRT1	3	affinity chromatography technology	Holloway KR (2010)	1
PIK3R2	3	SHC1	0	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009)	2
VAV1	2	ABL1	9	pull down, two hybrid, affinity chromatography technology, enzymatic study	Bassermann F (2002), Bassermann F (2002), Bassermann F (2002), Bassermann F (2002)	4
CSF1R	0	GRB2	2	two hybrid, pull down, affinity chromatography technology	Mancini A (1997), Mancini A (1997), Wang Y (1999)	3
JAK2	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Yu L (2009), Yu L (2009)	2
CRK	0	SOCS1	1	pull down, two hybrid	De Sepulveda P (1999), Grossmann A (2015)	2
ERBB2	6	CLNK	2	unspecified method	Jones RB (2006)	1
PTPN6	0	LAT	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Matalon O (2016), Matalon O (2016), Matalon O (2016)	3
CUL3	17	PIK3R2	3	affinity chromatography technology	Bennett EJ (2010)	1
CRKL	1	KHDRBS1	1	two hybrid	Wang J (2011)	1
FGFR2	6	PTPN11	20	two hybrid	Yao Z (2017)	1
LCK	0	PIK3R1	6	pull down	Kapeller R (1994)	1
SHC1	0	IL6ST	0	affinity chromatography technology, pull down	Giordano V (1997), Giordano V (1997)	2
GRB2	2	FLT3	5	affinity chromatography technology	Zhang S (1999)	1
RNF19B	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
MED28	2	PIK3R2	3	affinity chromatography technology	Lu M (2006)	1
SQSTM1	0	FAS	2	affinity chromatography technology, affinity chromatography technology	Liang X (2013), Liang X (2013)	2
SH3KBP1	1	CRK	0	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
SH3KBP1	1	ARHGAP17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havrylov S (2009), Wells CD (2006), Huttlin EL (2017)	3
FYN	1	GRB10	4	enzymatic study	Langlais P (2000)	1
FYN	1	KHDRBS1	1	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study	Oneyama C (2002), Fusaki N (1997), Loewenberg M (2006), Asbach B (2012), Asbach B (2012), Kaabeche K (2004)	6
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
PCBP1	2	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LTK	2	SHC1	0	affinity chromatography technology, affinity chromatography technology	Ueno H (1995), Ueno H (1995)	2
NTRK1	1	PCBP1	2	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	GAB2	3	affinity chromatography technology	Emdal KB (2015)	1
CBL	7	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Momose H (2003)	2
SH3KBP1	1	INPP5D	2	affinity chromatography technology, two hybrid	Kowanetz K (2004), Conde C (2012)	2
PIK3R1	6	BRCA1	7	pull down	Ren SY (2005)	1
SOS1	5	LAT	0	imaging technique	Houtman JC (2006)	1
CD244	1	PIK3R1	6	affinity chromatography technology	Huttlin EL (2015)	1
EP300	36	ESR1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Fajas L (2002), Fan S (2002), Fan S (2002), Fan S (2002), Kang YK (2002), Kang YK (2002), Hao L (2010), Jin W (2008), Cui Y (2006), Dutertre M (2003), Dutertre M (2003), Shiozawa T (2003), Kim SH (2010), Ma Y (2010), Ma Y (2010), Fujita T (2003), Likhite VS (2004), Band AM (2011), Loven MA (2004), Nalvarte I (2010), Yi P (2015)	21
ARHGAP32	11	EGFR	5	affinity chromatography technology	Nakamura T (2002)	1
FGFR1	2	PTPN11	20	affinity chromatography technology	Vecchione A (2007)	1
EGFR	5	EZR	8	protein complementation assay	Petschnigg J (2014)	1
GRB2	2	EP300	36	two hybrid	Bandyopadhyay S (2010)	1
CBLB	3	PLCG2	11	affinity chromatography technology	Yasuda T (2002)	1
CTNNB1	30	TGFBR2	0	affinity chromatography technology	Tian YC (2002)	1
VSIG4	1	ERBB2	6	affinity chromatography technology	Huttlin EL (2015)	1
PIK3R1	6	WAS	0	affinity chromatography technology, pull down	Banin S (1996), Banin S (1996)	2
FLT1	4	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Zhao WD (2010), Zhao WD (2010)	2
PIK3R3	0	FYN	1	two hybrid	Grossmann A (2015)	1
PTPN6	0	BCR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liedtke M (1998), Liedtke M (1998), Li X (2016)	3
TGFBR2	0	PIK3R3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VAV1	2	PDGFRB	8	affinity chromatography technology, unspecified method	Moores SL (2000), Liu BA (2012)	2
INPPL1	6	PIK3R1	6	affinity chromatography technology	Brehme M (2009)	1
HAVCR2	0	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
FGFR2	6	CBL	7	affinity chromatography technology	Kaabeche K (2004)	1
FASLG	0	FYN	1	pull down, pull down, pull down, unspecified method, imaging technique	Wenzel J (2001), Hane M (1995), Zuccato E (2007), Voss M (2009), Chen TC (2014)	5
PTK2	2	SYK	3	affinity chromatography technology, affinity chromatography technology	Chung J (1997), Sada K (1997)	2
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
PDGFRA	3	PIK3CA	8	affinity chromatography technology, enzymatic study	Valius M (1993), Valius M (1993)	2
ARHGAP32	11	PIK3R1	6	affinity chromatography technology	Moon SY (2003)	1
PIK3R3	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
NTRK1	1	PIK3R2	3	affinity chromatography technology	Emdal KB (2015)	1
PIK3R1	6	CYP4A11	0	two hybrid	Wang J (2008)	1
IRS1	7	PLCG2	11	unspecified method	Liu BA (2012)	1
AXL	4	TYRO3	4	two hybrid	Hafizi S (2005)	1
JAK2	1	EPOR	3	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Huang LJ (2001), Huang LJ (2001), Witthuhn BA (1993), van den Akker E (2004)	4
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
HAVCR2	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
ALK	8	MAP3K5	1	affinity chromatography technology	Crockett DK (2004)	1
GAB1	3	PTPN11	20	affinity chromatography technology, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Saito Y (2002), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004), Kapoor GS (2004), Kapoor GS (2004), Kapoor GS (2010), Fan YX (2013)	9
SHC1	0	BCR	3	affinity chromatography technology	Brehme M (2009)	1
AKT1	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Xiong Y (2009), Xiong Y (2009), Ivanov AA (2017)	3
CRK	0	RET	3	pull down, imaging technique	Bocciardi R (1997), Chen TC (2014)	2
STAT3	0	SH2D2A	2	two hybrid	Grossmann A (2015)	1
AKT1	1	PTK2	2	imaging technique	Moon HE (2015)	1
PIK3R1	6	RRAS2	0	affinity chromatography technology	Rong R (2002)	1
NLGN3	3	PIK3CB	2	affinity chromatography technology	Huttlin EL (2017)	1
PXN	1	FYN	1	affinity chromatography technology	Chen LM (2000)	1
SH3KBP1	1	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Tibaldi EV (2003)	3
NTRK1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Takahashi Y (2011), Emdal KB (2015), Emdal KB (2015)	3
SELPLG	0	PIK3R1	6	affinity chromatography technology	Wang HB (2007)	1
CRK	0	SOS1	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Okada S (1996), Okada S (1996), Okada S (1996), Ingham RJ (1996), Brehme M (2009), Chen TC (2014)	6
SRC	2	RET	3	affinity chromatography technology	Melillo RM (1999)	1
FCGR2A	0	LAT	0	affinity chromatography technology	Tridandapani S (2000)	1
ERBB2	6	SYK	3	unspecified method	Jones RB (2006)	1
LCK	0	BRCA1	7	two hybrid	Hill SJ (2014)	1
EP300	36	RXRA	1	affinity chromatography technology, affinity chromatography technology	Zhao WX (2007), Zhao WX (2007)	2
TNS4	5	PIK3R1	6	two hybrid	Grossmann A (2015)	1
PIK3R1	6	FES	2	affinity chromatography technology	Izuhara K (1996)	1
GRB2	2	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Bisson N (2011), Huttlin EL (2017)	2
ERBB3	3	SHC1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Li J (2013), Hellyer NJ (2001)	5
STAT3	0	PIK3R3	0	two hybrid	Grossmann A (2015)	1
NTRK1	1	ACTA1	1	affinity chromatography technology	Emdal KB (2015)	1
IRS4	2	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
WDR26	6	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Ye Y (2016), Ye Y (2016)	2
VHL	0	SIRT1	3	affinity chromatography technology	Ji W (2014)	1
HAVCR2	0	ERBB2	6	affinity chromatography technology	Huttlin EL (2017)	1
IRS1	7	CBLB	3	affinity chromatography technology	Suzue N (2006)	1
NFKBIA	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IRS2	6	GRB2	2	unspecified method, affinity chromatography technology	Liu BA (2012), Bisson N (2011)	2
NTRK1	1	NPM1	0	affinity chromatography technology	Emdal KB (2015)	1
EFNB2	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2015)	1
CLNK	2	PIK3R1	6	two hybrid	Grossmann A (2015)	1
CLNK	2	CRK	0	two hybrid	Grossmann A (2015)	1
PXK	1	PIK3R1	6	affinity chromatography technology	Takeuchi H (2010)	1
TGFBR2	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NPM1	0	WDR26	6	affinity chromatography technology	Chen R (2013)	1
KHDRBS1	1	CRK	0	pull down	Koch CA (1992)	1
LCK	0	SOS1	5	unspecified method	Tran T (2005)	1
LTK	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Kozutsumi H (1994), Ueno H (1997)	2
KHDRBS1	1	ITSN1	5	unspecified method	Asbach B (2012)	1
PIK3R1	6	INPP5D	2	affinity chromatography technology	Zhang S (1999)	1
TNFRSF1A	3	JAK2	1	pull down, affinity chromatography technology, affinity chromatography technology	Guo D (1998), Guo D (1998), Pincheira R (2008)	3
EGFR	5	PIK3R2	3	affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid, pull down, protein complementation assay	Tong J (2009), Jones RB (2006), Foerster S (2013), Kotlyar M (2015), Gout I (1992), Petschnigg J (2014)	6
EPOR	3	GRB2	2	pull down, pull down, affinity chromatography technology	Tauchi T (1995), Feng GS (1996), Barber DL (1997)	3
ITSN1	5	RAB5A	0	protein complementation assay	Wong KA (2012)	1
FBXL2	2	PIK3R2	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Kuchay S (2013), Kuchay S (2013), Kuchay S (2013)	3
NCK1	0	INPP5D	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
PTPRK	1	ARHGAP32	11	bioid	St-Denis N (2016)	1
PDGFRB	8	STAT3	0	imaging technique	Chen TC (2014)	1
ABI1	1	CBL	7	affinity chromatography technology	Tanos BE (2007)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
HDAC3	5	AKT1	1	affinity chromatography technology	Zampetaki A (2010)	1
SHB	4	ZAP70	5	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
LCK	0	WAS	0	affinity chromatography technology, enzymatic study	Nervi S (2005), Torres E (2006)	2
SH2D2A	2	SRC	2	unspecified method, affinity chromatography technology	Sun Z (2012), Sun Z (2012)	2
EGFR	5	EPN1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sigismund S (2005), Bertelsen V (2011), Kazazic M (2009)	3
RXRA	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Zhou H (2010), Zhou H (2010)	2
EGFR	5	DOK1	2	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
VSIG4	1	PIK3R2	3	affinity chromatography technology	Huttlin EL (2015)	1
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
EPOR	3	SYK	3	affinity chromatography technology	Duprez V (1998)	1
FYN	1	MAPT	1	affinity chromatography technology, pull down, pull down, enzymatic study	Klein C (2002), Klein C (2002), Bhaskar K (2005), Bhaskar K (2005)	4
INPPL1	6	BCAR1	6	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, far western blotting, pull down	Prasad N (2001), Prasad N (2001), Prasad N (2001), Prasad N (2001), Prasad N (2001), Prasad N (2001)	6
CBL	7	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jain SK (1997), Liu SK (1998), Ettenberg SA (1999), Wong A (2002), Wong A (2002), Robertson H (1997), Donovan JA (1994), Park RK (1999), Erdreich-Epstein A (1999), Gesbert F (1998), Gesbert F (1998), Gesbert F (1998), Husson H (1997), Saci A (2002), Odai H (1997), Ng C (2008), Khan EM (2008), Bandyopadhyay S (2010), Jiang X (2003), Waterman H (2002), Miraoui H (2010), Ravid T (2004), Ingham RJ (1996), Erdreich-Epstein A (1997), Rellahan BL (2003), Izadi KD (1998), Wang Y (1999), Chu J (1998), Bonita DP (1997), Boussiotis VA (1997), Meisner H (1995), Meisner H (1995), Barber DL (1997), Shishido T (2000), Bartkiewicz M (1999), Buday L (1996), Tarcic G (2009), Belleudi F (2007), Brizzi MF (1996), Brenner B (2001), Donovan JA (1996), Donovan JA (1996), Donovan JA (1996), Gaston I (2004), Gaston I (2004), Tsygankov AY (1996), Tsygankov AY (1996), Hunter S (1997), Jain SK (1997), Levkowitz G (1996), Liu YC (1997), Odai H (1995), Odai H (1995), Meisner H (1995), Huang JY (2000), Panchamoorthy G (1996), Panchamoorthy G (1996), Yokouchi M (1997), Oda A (1996), Fukazawa T (1995), Fukazawa T (1995), Selbach M (2006), Brehme M (2009), Brehme M (2009), Fukazawa T (1995), Cerboni C (1998), Cerboni C (1998), Fixman ED (1997), Anderson SM (1997), Houtman JC (2006), Brizzi MF (1996), Scott RP (2005), Scott RP (2005), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Umehara H (2002), Taipale M (2014), Taipale M (2014), Grossmann A (2015), Grossmann A (2015), Igloi Z (2015), Huttlin EL (2017)	83
APPL1	1	PIK3R2	3	two hybrid	Grossmann A (2015)	1
PROM1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Wei Y (2013), Wei Y (2013), Wei Y (2013)	3
FER	1	PIK3R3	0	two hybrid	Grossmann A (2015)	1
CD3E	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	de Aos I (1997), Alcazar I (2009)	2
SRC	2	PIK3R3	0	two hybrid	Grossmann A (2015)	1
EGFR	5	IRS1	7	unspecified method	Jones RB (2006)	1
SHC1	0	DOK1	2	affinity chromatography technology, affinity chromatography technology, unspecified method	Dunant NM (2000), Dunant NM (2000), Liu BA (2012)	3
PLCG2	11	VAV1	2	affinity chromatography technology	Guo B (2000)	1
TNFRSF1A	3	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
IRS2	6	EPOR	3	affinity chromatography technology	Verdier F (1997)	1
MAP3K5	1	PTPN11	20	affinity chromatography technology, enzymatic study	Yu L (2009), Yu L (2009)	2
SHC1	0	ACTA1	1	affinity chromatography technology	Brehme M (2009)	1
YWHAG	5	ARAF	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Jin J (2004), So J (2015), Ivanov AA (2017)	4
SRC	2	SYK	3	enzymatic study, affinity chromatography technology, enzymatic study	Kurosaki T (1994), Asazuma N (1997), Hirose M (2004)	3
HRAS	2	CBL	7	affinity chromatography technology	Lito P (2008)	1
CBLB	3	LCK	0	affinity chromatography technology	Kumar S (2011)	1
VHL	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Chen K (2016), Chen K (2016)	2
RIPK4	0	SQSTM1	0	affinity chromatography technology	Rodriguez J (2016)	1
FLT1	4	PTPN11	20	imaging technique	Chen TC (2014)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
CRK	0	BCR	3	pull down, affinity chromatography technology	Ingham RJ (1996), Brehme M (2009)	2
IFNAR1	4	PIK3R1	6	affinity chromatography technology	Rani MR (1999)	1
TGFBR2	0	CBL	7	pull down, affinity chromatography technology, enzymatic study	Zuo W (2013), Zuo W (2013), Zuo W (2013)	3
VHL	0	EPOR	3	affinity chromatography technology, affinity chromatography technology, pull down	Heir P (2016), Heir P (2016), Heir P (2016)	3
KHDRBS1	1	SH3KBP1	1	unspecified method, affinity chromatography technology	Asbach B (2012), Havrylov S (2009)	2
CUL3	17	YWHAG	5	affinity chromatography technology	Bennett EJ (2010)	1
GRB2	2	BCAR1	6	affinity chromatography technology, pull down, affinity chromatography technology	Wang X (2000), Angers-Loustau A (1999), Ambrogio C (2005)	3
5175	0	INPP5D	2	pull down, far western blotting	Pumphrey NJ (1999), Pumphrey NJ (1999)	2
CBL	7	RET	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Carniti C (2003), Carniti C (2003), Scott RP (2005)	3
NTRK1	1	CRKL	1	affinity chromatography technology	Emdal KB (2015)	1
FAS	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Kleber S (2008), Kleber S (2008)	2
SRC	2	GRB10	4	enzymatic study	Langlais P (2000)	1
PTTG1	0	PIK3R1	6	affinity chromatography technology	Chamaon K (2005)	1
SRC	2	KHDRBS1	1	two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Stelzl U (2005), Oneyama C (2002), Koch CA (1992), Shen Z (1999), Shen Z (1999), Finan PM (1996), Asbach B (2012), Asbach B (2012), Asbach B (2012), Kaabeche K (2004), Pincheira R (2008), Wong G (1992), Williger BT (1997), Wong BR (1999)	14
DOK1	2	CRKL	1	pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, two hybrid	van Dijk TB (2000), Bhat A (1998), Bhat A (1998), Bhat A (1998), Bhat A (1998), Martelli MP (2001), Grossmann A (2015)	7
PIK3R2	3	PTPN11	20	affinity chromatography technology	Brehme M (2009)	1
PTK2	2	SH3KBP1	1	affinity chromatography technology	Schmidt MH (2003)	1
TUBA1B	0	CD247	1	affinity chromatography technology	Serrador JM (2004)	1
SYK	3	MAPT	1	enzymatic study, affinity chromatography technology	Lebouvier T (2008), Lebouvier T (2008)	2
PTK2	2	RET	3	imaging technique	Chen TC (2014)	1
CBLB	3	PTPN11	20	affinity chromatography technology	Hoff H (2007)	1
SOS1	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hadari YR (1998), Chin H (1997), Kapoor GS (2010), Yu WM (2006)	4
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
GRB10	4	EGFR	5	pull down, two hybrid, protein complementation assay	He W (1998), Kotlyar M (2015), Petschnigg J (2014)	3
AKT1	1	SRC	2	imaging technique, affinity chromatography technology	Chen TC (2014), Lee J (2013)	2
FAS	2	CTNNB1	30	imaging technique	Chen TC (2014)	1
CRKL	1	SOS1	5	affinity chromatography technology	Hein MY (2015)	1
PIK3R1	6	JAK2	1	pull down, genetic interference	Ren SY (2005), Shen JP (2017)	2
FASLG	0	GRB2	2	affinity chromatography technology, pull down, pull down	Ghadimi MP (2002), Ghadimi MP (2002), Wenzel J (2001)	3
LAT	0	PIK3R1	6	affinity chromatography technology, pull down	Paz PE (2001), Paz PE (2001)	2
CD244	1	FYN	1	affinity chromatography technology	Chen R (2004)	1
ALK	8	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004), Bai RY (1998), Ambrogio C (2005), Ambrogio C (2005)	5
CUL3	17	IRS4	2	affinity chromatography technology	Bennett EJ (2010)	1
PTK2	2	IRS1	7	two hybrid, affinity chromatography technology	Lebrun P (1998), Lebrun P (1998)	2
IRS1	7	PIK3R3	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Xia X (1999), Mothe I (1997), Grossmann A (2015), Grossmann A (2015)	4
IGF1R	5	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
PIK3R1	6	ADAMTS2	6	two hybrid	Wang J (2008)	1
VAV1	2	PTPN6	0	pull down	Kon-Kozlowski M (1996)	1
TLR3	2	SYK	3	affinity chromatography technology	Lin YC (2013)	1
ARHGAP32	11	GAB1	3	affinity chromatography technology	Zhao C (2003)	1
AGAP2	14	AKT1	1	pull down, fluorescent resonance energy transfe, affinity chromatography technology	Qi Q (2013), Qi Q (2013), Qi Q (2013)	3
SOS1	5	BCR	3	affinity chromatography technology, affinity chromatography technology	Puil L (1994), Maru Y (1995)	2
FGFR1	2	SRC	2	affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Vecchione A (2007)	2
ALK	8	PXN	1	affinity chromatography technology	Ambrogio C (2005)	1
GNB1	4	WDR26	6	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun Z (2011), Sun Z (2011), Sun Z (2011), Sun Z (2011), Sun Z (2013), Ye Y (2016)	6
RIPK4	0	ARAF	0	affinity chromatography technology	Rodriguez J (2016)	1
ARHGAP17	1	CRK	0	pull down	Richnau N (2001)	1
FLRT1	4	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
INPPL1	6	INPP5D	2	affinity chromatography technology	Brehme M (2009)	1
STAT3	0	FYN	1	pull down	Schreiner SJ (2002)	1
SOS1	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000)	2
MAPT	1	TUBA1B	0	pull down	Flach K (2014)	1
NCK1	0	FASLG	0	pull down, unspecified method	Wenzel J (2001), Voss M (2009)	2
ERBB2	6	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, far western blotting	Schroeder JA (2002), Bonvini P (2001), Schroeder JA (2002), Schroeder JA (2002), Kanai Y (1995), Kanai Y (1995)	6
RIPK4	0	TUBA1B	0	affinity chromatography technology	Rodriguez J (2016)	1
GRB2	2	SH3KBP1	1	pull down, pull down	Gout I (2000), Borinstein SC (2000)	2
CRK	0	PIK3CB	2	affinity chromatography technology	Brehme M (2009)	1
LAT	0	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Paz PE (2001), Zhang W (1998), Perez-Villar JJ (2002), Motto DG (1994), Houtman JC (2006)	5
CRKL	1	GAB1	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Sakkab D (2000), Sakkab D (2000), Chen TC (2014)	3
NTRK1	1	GSPT1	3	affinity chromatography technology	Emdal KB (2015)	1
IGF1R	5	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Dey BR (1996), Santen RJ (2005), Tartare-Deckert S (1995), Song RX (2004), Yoshimaru T (2013)	5
RASD2	1	GNB1	4	two hybrid	Hill C (2009)	1
ABL1	9	PTPN6	0	affinity chromatography technology	Kharbanda S (1996)	1
PTTG1	0	EZR	8	genetic interference	Vizeacoumar FJ (2013)	1
ABL1	9	PDE4D	4	far western blotting	Beard MB (1999)	1
FCGR2A	0	CBL	7	biochemical	Marois L (2009)	1
AKT1	1	ACTA1	1	affinity chromatography technology, affinity chromatography technology	Foster KS (2006), Kim JH (2013)	2
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
CTNNB1	30	ABL1	9	affinity chromatography technology, affinity chromatography technology	Chen R (2013), Chen R (2013)	2
PDGFRA	3	CRK	0	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yokote K (1998), Matsumoto T (2000), Matsumoto T (2000), Chen TC (2014)	4
NTRK1	1	KHDRBS1	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Qian X (1998), Borrello MG (1994), Nakamura T (2002), Meakin SO (1999), Koch A (2000), Emdal KB (2015), Emdal KB (2015)	7
ABL1	9	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009)	2
GRB2	2	SOCS1	1	pull down	De Sepulveda P (1999)	1
EGFR	5	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soubeyran P (2002), Szymkiewicz I (2002), Schmidt MH (2004), Schmidt MH (2003), Ronning SB (2011), Ronning SB (2011), Yang S (2006), Schmidt MH (2003)	8
EGFR	5	SOCS6	0	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
PTPRK	1	EGFR	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WDR26	6	PIK3R1	6	affinity chromatography technology	Ye Y (2016)	1
CRK	0	SOCS6	0	two hybrid	Grossmann A (2015)	1
ERBB3	3	CRK	0	unspecified method	Jones RB (2006)	1
CLNK	2	SOCS6	0	two hybrid	Grossmann A (2015)	1
LCK	0	PIK3CA	8	affinity chromatography technology, pull down	Sade H (2004), Prasad KV (1993)	2
NPM1	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Sato K (2004), Ertych N (2016)	2
LCK	0	LAT	0	biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Jiang Y (2007), Jiang Y (2007)	4
NISCH	11	IRS2	6	affinity chromatography technology	Sano H (2002)	1
BCAR1	6	PTPN11	20	affinity chromatography technology	Manie SN (1997)	1
MED28	2	SRC	2	affinity chromatography technology	Lu M (2006)	1
JAK2	1	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chauhan D (1995), Chauhan D (1995), Giorgetti-Peraldi S (1995), Brizzi MF (1996)	4
CRK	0	SH2D2A	2	two hybrid	Grossmann A (2015)	1
PIK3R1	6	GRB10	4	affinity chromatography technology	Deng Y (2003)	1
SYK	3	PIK3R1	6	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Moon KD (2005), Moon KD (2005), Moon KD (2005), Moon KD (2005), Huang ZY (2006)	5
ALK	8	STAT3	0	affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004)	2
LCK	0	SQSTM1	0	pull down	Joung I (1996)	1
AXL	4	PIK3R2	3	enzymatic study	Braunger J (1997)	1
PTK2	2	STAT3	0	affinity chromatography technology, imaging technique	Ryu H (2000), Chen TC (2014)	2
FYN	1	ARHGAP32	11	two hybrid, pull down, affinity chromatography technology	Taniguchi S (2003), Taniguchi S (2003), Taniguchi S (2003)	3
FER	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
EGFR	5	TNFRSF1A	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
HDAC3	5	NFKBIA	0	affinity chromatography technology	Gao Z (2006)	1
PDGFRB	8	SHC1	0	affinity chromatography technology, affinity chromatography technology	Yokote K (1994), Yokote K (1994)	2
IL6ST	0	JAK2	1	affinity chromatography technology	Kim H (1997)	1
FGFR1	2	GAB1	3	affinity chromatography technology	Vecchione A (2007)	1
PIK3R1	6	MAP3K5	1	affinity chromatography technology, affinity chromatography technology	Xie D (2009), Xie D (2009)	2
FASLG	0	SRC	2	unspecified method	Voss M (2009)	1
SYNM	3	GRB2	2	affinity chromatography technology, affinity chromatography technology	Anggono V (2007), David C (1996)	2
PTPN11	20	CTNNB1	30	affinity chromatography technology	Ukropec JA (2000)	1
NCK1	0	PTK2	2	pull down, affinity chromatography technology, pull down	Minegishi M (1996), Goicoechea SM (2002), Goicoechea SM (2002)	3
IL6ST	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lehmann U (2003), Anhuf D (2000), Kim H (1997), Schmitz J (2000)	4
NLGN3	3	PIK3R3	0	affinity chromatography technology	Huttlin EL (2017)	1
SH3KBP1	1	CBLB	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down	Szymkiewicz I (2002), Szymkiewicz I (2002), Szymkiewicz I (2002), Havrylov S (2009), Moncalian G (2006), Jozic D (2005), Jozic D (2005), Kowanetz K (2003), Ceregido MA (2013), Ceregido MA (2013), Ceregido MA (2013)	11
RASD2	1	PIK3R1	6	affinity chromatography technology, pull down	Bang S (2012), Bang S (2012)	2
SHC1	0	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wisniewski D (1999), Puil L (1994), Brehme M (2009), Brehme M (2009), Brehme M (2009)	5
CRK	0	ARHGAP32	11	pull down, affinity chromatography technology, affinity chromatography technology	Zhao C (2003), Zhao C (2003), Moon SY (2003)	3
SQSTM1	0	PIK3R1	6	far western blotting, affinity chromatography technology	Sung CK (1998), Sung CK (1998)	2
DNM2	2	PDGFRA	3	affinity chromatography technology	Feng H (2012)	1
EP300	36	SRC	2	affinity chromatography technology, affinity chromatography technology	Paladino D (2016), Paladino D (2016)	2
5175	0	PTPN11	20	affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Ilan N (2000), Pumphrey NJ (1999), Pumphrey NJ (1999), Hua CT (1998), Hua CT (1998), Jackson DE (1997), Jackson DE (1997)	7
CLNK	2	PIK3R3	0	two hybrid	Grossmann A (2015)	1
CRK	0	PIK3R3	0	affinity chromatography technology, two hybrid	Brehme M (2009), Grossmann A (2015)	2
PTPN11	20	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002), Lynch DK (2002), Zhao C (1999), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Cholay M (2010), van den Akker E (2004), Arnaud M (2004), Arnaud M (2004), Yu WM (2006), Yu WM (2006)	13
CBLB	3	ZAP70	5	affinity chromatography technology, affinity chromatography technology	Zhang Z (1999), Kumar S (2011)	2
SHC1	0	NTRK2	10	pull down	Meakin SO (1999)	1
PIK3R1	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang S (1999), Takahashi Y (1999), Craddock BL (1997), Wu CJ (2000), Wu CJ (2001), Yu WM (2006)	6
NYAP1	4	PIK3R1	6	pull down	Yokoyama K (2011)	1
PTPN11	20	IRS1	7	pull down, affinity chromatography technology, unspecified method, pull down, enzymatic study	Kuhne MR (1993), Myers MG (1998), Liu BA (2012), Strack V (2002), Strack V (2002)	5
CBL	7	EPHA2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2002), Chakraborty S (2012), Walker-Daniels J (2002), Walker-Daniels J (2002), Dutta D (2013)	5
YWHAG	5	IGF1R	5	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
CBL	7	ZAP70	5	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, x-ray crystallography	Lupher ML (1996), Meng W (1999), Wang HY (2001), Rao N (2000), Lupher ML (1997), Okabe S (2006), Zhang Z (1999), Lupher ML (1996), Dou H (2012), Dou H (2012), Gabrielsen M (2017)	11
CRKL	1	PTPN11	20	affinity chromatography technology	Chin H (1997)	1
HTT	14	EGFR	5	affinity chromatography technology	Liu YF (1997)	1
CRK	0	INPPL1	6	affinity chromatography technology	Brehme M (2009)	1
VAV1	2	EGFR	5	affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Moores SL (2000), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	4
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
EGFR	5	DNM2	2	affinity chromatography technology	Tong J (2014)	1
CUL3	17	NCL	1	affinity chromatography technology	Bennett EJ (2010)	1
NISCH	11	PIK3R1	6	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	PTK2	2	affinity chromatography technology	Emdal KB (2015)	1
CBL	7	PXN	1	affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Salgia R (1996)	2
FYN	1	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Tang H (1999), Chernock RD (2001)	2
GRB2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Bennett AM (1994), Ward AC (1998), Yin T (1997), Tang J (1997), Tang H (1999), Hadari YR (1998), Zhang S (1999), Wong L (1996), Brehme M (2009), Craddock BL (1997), Bisson N (2011), Blagoev B (2003), Bisson N (2011), Tauchi T (1995), Huttlin EL (2017), Kapoor GS (2010), Kapoor GS (2010), Vogel W (1996), Vogel W (1996), Yu WM (2006)	21
VAV1	2	ZAP70	5	pull down, affinity chromatography technology	Katzav S (1994), Huby RD (1995)	2
CD28	0	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
IRS4	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
GRB2	2	WAS	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Banin S (1996), She HY (1997), She HY (1997), She HY (1997)	4
FLRT1	4	PIK3CB	2	affinity chromatography technology	Huttlin EL (2017)	1
ABI1	1	ABL1	9	pull down, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology	Tani K (2003), Biesova Z (1997), Yamamoto A (2001), Xiong X (2008), Xiong X (2008), Xiong X (2008)	6
SHB	4	PIK3R1	6	pull down, affinity chromatography technology	Karlsson T (1995), Karlsson T (1995)	2
IRS1	7	PIK3CB	2	affinity chromatography technology	Kuchay S (2013)	1
BRCA1	7	NCL	1	affinity chromatography technology	Ertych N (2016)	1
AKT1	1	CTNNB1	30	enzymatic study, enzymatic study	Tian Q (2004), Fang D (2007)	2
FGFR1	2	ERBB3	3	unspecified method	Jones RB (2006)	1
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
HTT	14	CTNNB1	30	affinity chromatography technology	Godin JD (2010)	1
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
SRC	2	JAK2	1	affinity chromatography technology	Liang K (2010)	1
IRS2	6	SIRT1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology	Zhang J (2007), Zhang J (2007), Froejdoe S (2011)	3
EGFR	5	IGF1R	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Morgillo F (2006), Riedemann J (2007), Riedemann J (2007)	3
FCGR2A	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
LCP2	0	NCK1	0	affinity chromatography technology, pull down, affinity chromatography technology	Shim EK (2004), Wunderlich L (1999), de Castro RO (2012)	3
ARHGAP32	11	SHC1	0	affinity chromatography technology	Nakamura T (2002)	1
ARAF	0	RRAS2	0	two hybrid	Yuryev A (2003)	1
NCK1	0	PIK3R1	6	affinity chromatography technology	Gelkop S (2001)	1
PTK2	2	FYN	1	affinity chromatography technology, x-ray crystallography	Messina S (2003), Arold ST (2001)	2
TGFBR2	0	SH3KBP1	1	affinity chromatography technology	Yakymovych I (2015)	1
GAB2	3	CD247	1	affinity chromatography technology	Yamasaki S (2001)	1
NISCH	11	IRS1	7	affinity chromatography technology	Sano H (2002)	1
TYRO3	4	SRC	2	affinity chromatography technology	Toshima J (1995)	1
FER	1	CRK	0	two hybrid	Grossmann A (2015)	1
NTRK1	1	CTNNB1	30	affinity chromatography technology	Emdal KB (2015)	1
CSF1R	0	SOS1	5	affinity chromatography technology, affinity chromatography technology	Wang Y (1999), Wang Y (1999)	2
LCK	0	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Venkitachalam S (2011), Venkitachalam S (2011)	2
SOS1	5	ITSN1	5	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Tong XK (2000), Tong XK (2000), Bandyopadhyay S (2010), Tsyba L (2008), Wang JB (2005)	5
AKT1	1	PIK3CB	2	biochemical	Wan C (2015)	1
SOCS1	1	ERBB2	6	unspecified method	Jones RB (2006)	1
ESR1	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Castoria G (2001), Simoncini T (2000), Simoncini T (2000)	3
FGFR1	2	SOS1	5	imaging technique	Chen TC (2014)	1
PIK3R1	6	NYAP2	2	affinity chromatography technology, pull down	Hein MY (2015), Yokoyama K (2011)	2
TUBA1B	0	ZAP70	5	affinity chromatography technology	Serrador JM (2004)	1
CUL3	17	NISCH	11	affinity chromatography technology	Bennett EJ (2010)	1
GRB2	2	PTPN6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Kon-Kozlowski M (1996), Saci A (2002)	3
PTGER3	2	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IL1R1	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Reddy SA (1997), Reddy SA (1997)	2
FAS	2	SRC	2	affinity chromatography technology	Kleber S (2008)	1
GNB1	4	GNAQ	1	biochemical	Wan C (2015)	1
SOCS6	0	IRS4	2	affinity chromatography technology	Krebs DL (2002)	1
ZAP70	5	ABL1	9	affinity chromatography technology	Neumeister EN (1995)	1
GRB2	2	SYN1	1	pull down, affinity chromatography technology	McPherson PS (1994), David C (1996)	2
NTRK1	1	GNB1	4	affinity chromatography technology	Emdal KB (2015)	1
PIK3R3	0	NISCH	11	affinity chromatography technology	Huttlin EL (2017)	1
ERBB2	6	GAB1	3	enzymatic study	Fan YX (2013)	1
ERBB3	3	SYK	3	unspecified method	Jones RB (2006)	1
CD40	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Ha YJ (2011), Ha YJ (2011)	2
PIK3CA	8	SQSTM1	0	two hybrid	Wang J (2008)	1
DNM2	2	ITSN1	5	two hybrid, pull down, pull down	Vinayagam A (2011), Solomaha E (2005), Elhamdani A (2006)	3
PLCG2	11	SHC1	0	affinity chromatography technology, affinity chromatography technology	Perskvist N (2000), Boudot C (2002)	2
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
PIK3R3	0	PIK3CD	4	affinity chromatography technology	Huttlin EL (2017)	1
SOCS6	0	PIK3R1	6	affinity chromatography technology	Krebs DL (2002)	1
KIT	4	GRB2	2	two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down	De Sepulveda P (1999), Thoemmes K (1999), Feng GS (1996), Sun J (2007), Zhu MJ (2007), Wollberg P (2003), Brizzi MF (1996)	7
GRB2	2	PDE4D	4	far western blotting	Beard MB (1999)	1
DEFA5	1	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
CBL	7	AXL	4	affinity chromatography technology	Valverde P (2005)	1
NTRK1	1	DNM2	2	affinity chromatography technology	Emdal KB (2015)	1
GRB2	2	NISCH	11	affinity chromatography technology	Bisson N (2011)	1
ARAF	0	PIK3R1	6	pull down	Fang Y (2002)	1
FLT1	4	SHC1	0	two hybrid	Warner AJ (2000)	1
TNIP1	1	SELPLG	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Wang HB (2007), Wang HB (2007), Wang HB (2007)	3
APPL1	1	HDAC3	5	affinity chromatography technology	Joshi P (2013)	1
GNB1	4	PIK3CA	8	affinity chromatography technology	Xiong Y (2009)	1
IL6ST	0	ERBB2	6	affinity chromatography technology, affinity chromatography technology	Grant SL (2002), Grant SL (2002)	2
LAT	0	CBL	7	affinity chromatography technology	Jiang Y (2007)	1
ITSN1	5	PIK3R1	6	two hybrid	Wong KA (2012)	1
GAB2	3	ARHGAP32	11	two hybrid, affinity chromatography technology	Zhao C (2003), Zhao C (2003)	2
SOCS1	1	IRS2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rui L (2002), Rui L (2002), McCormick SM (2016), McCormick SM (2016)	4
NTRK1	1	IGF1R	5	affinity chromatography technology	Emdal KB (2015)	1
PIK3R1	6	CD7	0	pull down, affinity chromatography technology	Lee DM (1996), Subrahmanyam G (2003)	2
PDGFRA	3	CRKL	1	affinity chromatography technology, imaging technique	Yokote K (1998), Chen TC (2014)	2
PRMT2	3	HTT	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IRS2	6	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Argetsinger LS (1996), Verdier F (1997), Kim B (1998), Hamer I (2002), Calegari VC (2005), Tzatsos A (2009), Ren W (2013), Hein MY (2015)	8
NTRK1	1	CUL3	17	affinity chromatography technology	Emdal KB (2015)	1
PXN	1	NCK1	0	pull down	Turner CE (1999)	1
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
HDAC3	5	PIK3R1	6	affinity chromatography technology	Alam S (2011)	1
GRB2	2	YWHAG	5	affinity chromatography technology	Bisson N (2011)	1
RNF19B	0	PIK3R2	3	affinity chromatography technology	Huttlin EL (2017)	1
CSF1R	0	SHC1	0	affinity chromatography technology	Wang Y (1999)	1
ERBB3	3	PTPN11	20	affinity chromatography technology, two hybrid	Crovello CS (1998), Yao Z (2017)	2
GRB2	2	ALOX5	1	pull down, pull down	VanderNoot VA (1995), Lepley RA (1994)	2
PIK3R1	6	HRAS	2	affinity chromatography technology, pull down, imaging technique	Hanna AN (1999), Rodriguez-Viciana P (1997), Chen TC (2014)	3
NTRK1	1	GAB1	3	affinity chromatography technology	Emdal KB (2015)	1
ESR1	0	IRS1	7	affinity chromatography technology, affinity chromatography technology	Morelli C (2003), Morelli C (2003)	2
PIK3R1	6	GAB1	3	pull down, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology	Bertagnolo V (1998), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), Fan YX (2013)	7
KHDRBS1	1	VAV1	2	unspecified method	Asbach B (2012)	1
EPHA2	3	TGFBR1	2	affinity chromatography technology	Hein MY (2015)	1
IRS2	6	PTPN11	20	affinity chromatography technology	Argetsinger LS (1996)	1
WAS	0	CBLB	3	affinity chromatography technology	Watanabe Y (2013)	1
CBL	7	CSF1R	0	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mancini A (2002), Mancini A (2002), Mancini A (2002), Wilhelmsen K (2002), Wilhelmsen K (2002), Wang Y (1999), Wang Y (1999), Tanaka S (1995), Ota J (2000), Ota J (2000)	10
FLT3	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Hartman AD (2006), Hartman AD (2006)	2
SOS1	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Foehr ED (2000), Park RK (1999), Chin H (1997), Wang Y (1999), Brehme M (2009), Brizzi MF (1996), Yu WM (2006), Klint P (1995)	9
GNB1	4	PTK2	2	affinity chromatography technology	Knezevic N (2009)	1
ZAP70	5	LCP2	0	enzymatic study, enzymatic study	Raab M (1997), Kim KS (2002)	2
APPL1	1	PIK3R1	6	affinity chromatography technology, two hybrid	Yang L (2003), Grossmann A (2015)	2
KIT	4	CRK	0	two hybrid	Yokouchi M (1997)	1
KIT	4	INPP5D	2	pull down	van Dijk TB (2000)	1
BRCA1	7	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Li H (2010), Li H (2010), Li H (2010), Ertych N (2016)	4
IL20RA	2	STAT3	0	affinity chromatography technology	Huttlin EL (2017)	1
VHL	0	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Russell RC (2011), Russell RC (2011)	2
PTPN11	20	JAK2	1	pull down, enzymatic study, enzymatic study, affinity chromatography technology	Yin T (1997), Yin T (1997), Tauchi T (1996), Maegawa H (1996)	4
JAK2	1	VAV1	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Matsuguchi T (1995)	3
SOCS1	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
FLRT1	4	PIK3R2	3	affinity chromatography technology	Huttlin EL (2017)	1
TMEM17	0	EPN1	4	bioid	Gupta GD (2015)	1
APPL1	1	SOCS6	0	two hybrid	Grossmann A (2015)	1
NTRK1	1	STAT3	0	affinity chromatography technology	Emdal KB (2015)	1
AXL	4	LCK	0	far western blotting	Braunger J (1997)	1
FAS	2	EZR	8	biochemical	Gajate C (2005)	1
EGFR	5	PIK3R3	0	unspecified method, two hybrid, imaging technique, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014)	4
IRS2	6	EPN1	4	affinity chromatography technology, affinity chromatography technology	Fukushima T (2015), Fukushima T (2015)	2
FAS	2	MAP3K5	1	affinity chromatography technology, imaging technique	Ko YG (2001), Chen TC (2014)	2
IGF1R	5	PIK3R1	6	imaging technique	Chen TC (2014)	1
FLRT1	4	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
STAT3	0	KHDRBS1	1	affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Sanchez-Margalet V (2001)	2
TGFBR1	2	PIK3R2	3	affinity chromatography technology	Krymskaya VP (1997)	1
YWHAG	5	MAP3K5	1	affinity chromatography technology	Wang H (2015)	1
HRAS	2	DAB2IP	3	affinity chromatography technology	Dai X (2014)	1
FYN	1	PLCG2	11	pull down	Pleiman CM (1993)	1
CSF1R	0	SOCS1	1	two hybrid, affinity chromatography technology, pull down	Bourette RP (2001), Bourette RP (2001), Bourette RP (2001)	3
PTK2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Manes S (1999), Takahashi A (2011)	2
CRKL	1	WAS	0	affinity chromatography technology, pull down	Oda A (2001), Oda A (2001)	2
RET	3	GRB10	4	two hybrid, pull down, affinity chromatography technology	Pandey A (1995), Pandey A (1995), Pandey A (1995)	3
FLRT1	4	PIK3R3	0	affinity chromatography technology	Huttlin EL (2017)	1
CD28	0	PIK3CA	8	affinity chromatography technology	Slavik JM (1999)	1
WAS	0	NCK1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Krause M (2000), Okabe S (2002), Rivero-Lezcano OM (1995), Rivero-Lezcano OM (1995), Buvall L (2013)	5
EGFR	5	INPPL1	6	affinity chromatography technology, affinity chromatography technology	Pesesse X (2001), Sanada F (2009)	2
NPM1	0	GRB2	2	affinity chromatography technology, pull down	Crockett DK (2004), Bai RY (1998)	2
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
NTRK1	1	INPPL1	6	affinity chromatography technology	Emdal KB (2015)	1
CBL	7	IRS1	7	affinity chromatography technology	Ahmed Z (2000)	1
KHDRBS1	1	LCK	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Fusaki N (1997), Loewenberg M (2006), Tran T (2005), Nervi S (2005)	4
FGFR2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Seo DW (2003)	2
ABI1	1	NCK1	0	pull down, affinity chromatography technology	Yamamoto A (2001), Cowan CA (2001)	2
PIK3R1	6	SH3KBP1	1	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid	Gout I (2000), Tossidou I (2010), Borthwick EB (2004), Borthwick EB (2004)	4
TMEM17	0	EPHA2	3	bioid	Gupta GD (2015)	1
IRS1	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Skolnik EY (1993), Skolnik EY (1993), Skolnik EY (1993), Morrison KB (2002), Giorgetti-Peraldi S (1995), Liu BA (2012), Bisson N (2011)	7
KIT	4	CSF2RA	1	imaging technique	Chen TC (2014)	1
PIK3R1	6	EPHA2	3	pull down, affinity chromatography technology, two hybrid	Pandey A (1994), Pandey A (1994), Pandey A (1994)	3
ERBB2	6	VAV1	2	unspecified method	Jones RB (2006)	1
PIK3R1	6	RET	3	pull down	Besset V (2000)	1
PTPN11	20	PDGFRA	3	affinity chromatography technology, enzymatic study	Feng H (2012), Vogel W (1996)	2
GNAQ	1	PIK3R1	6	affinity chromatography technology	Ballou LM (2003)	1
NTRK1	1	PIK3CB	2	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	TNS4	5	unspecified method	Jones RB (2006)	1
PIK3R1	6	PIK3R1	6	pull down	Kapeller R (1994)	1
NTRK1	1	APPL1	1	affinity chromatography technology	Emdal KB (2015)	1
PIK3R1	6	CHAF1A	1	affinity chromatography technology	Hein MY (2015)	1
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
ZDHHC17	1	GRB10	4	two hybrid	Butland SL (2014)	1
SRC	2	ERBB2	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Ren Z (2002), Li X (2007), Liang K (2010), Liang K (2010), Shen JP (2017)	5
PDGFRB	8	PIK3R3	0	imaging technique	Chen TC (2014)	1
EGFR	5	NCL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liccardi G (2014), Yao Z (2017), Goldshmit Y (2014)	3
CTNNB1	30	ESR1	0	affinity chromatography technology	Kouzmenko AP (2004)	1
EGFR	5	PDGFRB	8	affinity chromatography technology	Habib AA (1998)	1
PIK3R2	3	PIK3CB	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
JAK2	1	ERBB3	3	unspecified method	Jones RB (2006)	1
IRS1	7	KHDRBS1	1	affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Sung CK (1994)	2
PTK2	2	SRC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Hecker TP (2002), Angers-Loustau A (1999), Relou IA (2003), Messina S (2003), Lebrun P (1998), Ponnala S (2011), Grossmann A (2015), Chen TC (2014), Lee J (2013), Reiske HR (2000)	11
LAT	0	VAV1	2	pull down, pull down, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Perez-Villar JJ (2002)	3
CBL	7	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kassenbrock CK (2002), Rafiq K (2011), Rellahan BL (2003), Vantler M (2006), Shishido T (2000), Shishido T (2000), Song JJ (2010), Sanjay A (2006), Sanjay A (2006), Tanaka S (1995), Tanaka S (1995), Tanaka S (1995), Szymkiewicz I (2004), Hashimoto S (2006)	14
IGF1R	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Manes S (1999), Seely BL (1995), Seely BL (1995), Yao Z (2017)	4
ABL1	9	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, enzymatic study, two hybrid, enzymatic study	Brehme M (2009), Brehme M (2009), Brehme M (2009), Peterson ME (2008), Yoshida K (2005), Chen C (2008), Feller SM (1994), Feller SM (1994), Bai RY (1998), Ren J (2002)	10
SRC	2	RXRA	1	pull down	Sun Y (2004)	1
IL6ST	0	GRB2	2	pull down, affinity chromatography technology	Lee IS (1997), Lee IS (1997)	2
FLT3	5	CBL	7	affinity chromatography technology, affinity chromatography technology, pull down	Sargin B (2007), Sargin B (2007), Sargin B (2007)	3
SHC1	0	JAK2	1	pull down, pull down	VanderKuur J (1995), Giordano V (1997)	2
TMEM17	0	ARHGAP1	0	bioid	Gupta GD (2015)	1
SOS1	5	EGFR	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Qian X (2000), Qian X (1998), Buday L (1994), Tong J (2009), Kurada BR (2009), Tong J (2008), Foerster S (2013), Tong J (2014), Kapoor GS (2010)	9
FES	2	STAT3	0	affinity chromatography technology	Park WY (1998)	1
TGFBR1	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Yakymovych I (2015), Yakymovych I (2015)	2
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
PTGER3	2	PIK3R1	6	affinity chromatography technology	Huttlin EL (2015)	1
PDGFRA	3	KIT	4	affinity chromatography technology	Zhu MJ (2007)	1
CBLB	3	SHC1	0	affinity chromatography technology	Lavagna-Sevenier C (1998)	1
RIPK4	0	PIK3R3	0	affinity chromatography technology	Rodriguez J (2016)	1
ABL1	9	EGFR	5	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
RAB5A	0	PIK3CB	2	affinity chromatography technology	Schnatwinkel C (2004)	1
GRB2	2	LTK	2	affinity chromatography technology	Ueno H (1995)	1
IFNAR1	4	SOCS1	1	affinity chromatography technology	Piganis RA (2011)	1
STAT3	0	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Tsuruma R (2008), Kato M (2015)	5
DOK1	2	BCR	3	affinity chromatography technology, affinity chromatography technology, pull down	Bhat A (1998), Bhat A (1998), Bhat A (1998)	3
BCAR1	6	LCK	0	pull down	Manie SN (1997)	1
CBL	7	CBLB	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Rorsman C (2016)	2
IRS1	7	ALK	8	affinity chromatography technology	Crockett DK (2004)	1
FYN	1	CBLB	3	two hybrid	Grossmann A (2015)	1
GRB2	2	CD28	0	pull down, pull down	Okkenhaug K (1998), Nunes JA (1996)	2
RXRA	1	CTNNB1	30	affinity chromatography technology, imaging technique	Xiao JH (2003), Chen TC (2014)	2
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
ERBB3	3	TNS4	5	unspecified method	Jones RB (2006)	1
CD40	3	CBL	7	affinity chromatography technology	Deregibus MC (2003)	1
CMIP	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Kamal M (2010), Kamal M (2010)	2
AKT1	1	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Lin WN (2008), Lee IT (2010), Sundaresan NR (2011), Howie HL (2011), Chen J (2004), Chen J (2004)	6
CRK	0	PIK3CD	4	affinity chromatography technology	Brehme M (2009)	1
FER	1	ERBB3	3	unspecified method	Jones RB (2006)	1
APPL1	1	SH2D2A	2	two hybrid	Grossmann A (2015)	1
ESR1	0	CUL3	17	affinity chromatography technology	Byun B (2008)	1
PTK2	2	ERBB2	6	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Ritch PA (2003), Ritch PA (2003)	3
ABL1	9	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wisniewski D (1999), Brehme M (2009), Brehme M (2009)	3
GNB1	4	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Xiong Y (2009), Xiong Y (2009)	2
NTRK1	1	SRC	2	affinity chromatography technology	Emdal KB (2015)	1
ERBB2	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method	Schulze WX (2006), Bourguignon LY (2001), Olayioye MA (1998), Li X (2007), Li X (2007), Crovello CS (1998), Jones RB (2006)	7
CRKL	1	SYK	3	affinity chromatography technology, pull down	Oda A (2001), Oda A (2001)	2
SRC	2	5175	0	affinity chromatography technology, affinity chromatography technology	Cicmil M (2000), Relou IA (2003)	2
EGFR	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology, enzymatic study	Schulze WX (2006), Tomic S (1995), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Kapoor GS (2010), Vogel W (1996)	7
YWHAG	5	CHAF1A	1	two hybrid	Bandyopadhyay S (2010)	1
NCK1	0	SOCS1	1	pull down	De Sepulveda P (1999)	1
FYN	1	CBL	7	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Taher TE (2002), Deckert M (1998), Deckert M (1998), Deckert M (1998), Ghosh AK (2004), Rellahan BL (2003), Boussiotis VA (1997), Andoniou CE (2000), Shishido T (2000), Okabe S (2006), Kaabeche K (2004), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tsygankov AY (1996), Tanaka S (1995), Reedquist KA (1996), Grossmann AH (2004), Panchamoorthy G (1996), Fukazawa T (1995), Fukazawa T (1995), Fukazawa T (1995), Nishio H (2002), Anderson SM (1997), Fukazawa T (1996), Grossmann A (2015)	27
PXN	1	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kovacic-Milivojevic B (2001), Matsuya M (1998), Turner CE (1999), Liu S (2002), Liu S (2002), Mazaki Y (1997), Zheng C (1998), Brown MC (1996), Fujita H (1998), Zhang Z (1999), Wang JF (2000), Ivankovic-Dikic I (2000)	12
NCK1	0	PDGFRB	8	affinity chromatography technology, affinity chromatography technology	Li W (1992), Braverman LE (1999)	2
PIK3R3	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
ZAP70	5	PTPN6	0	pull down	Plas DR (1996)	1
NTRK1	1	PIK3R1	6	affinity chromatography technology	Emdal KB (2015)	1
ACTA1	1	PIK3R1	6	affinity chromatography technology	Kim JH (2013)	1
ESR1	0	GNB1	4	affinity chromatography technology, affinity chromatography technology	Tarallo R (2011), Han SJ (2016)	2
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
FGFR1	2	GNB1	4	affinity chromatography technology	Vecchione A (2007)	1
NTRK1	1	NCL	1	affinity chromatography technology	Emdal KB (2015)	1
CBL	7	VAV1	2	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Marengere LE (1997), Bertagnolo V (2001), Miura-Shimura Y (2003), Simmons A (2005), Shen M (2009), Shen M (2009), Lottin-Divoux S (2006), Lottin-Divoux S (2006), Peterson ME (2008)	12
CUL3	17	CTNNB1	30	affinity chromatography technology	Bennett EJ (2010)	1
PDGFRA	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIK3CD	4	PIK3R2	3	pull down, affinity chromatography technology, affinity chromatography technology	Vanhaesebroeck B (1997), Vanhaesebroeck B (1997), Brehme M (2009)	3
GAB2	3	GAB1	3	two hybrid	van den Akker E (2004)	1
FBXL2	2	PIK3R1	6	affinity chromatography technology	Kuchay S (2013)	1
RIPK4	0	PIK3R1	6	affinity chromatography technology	Rodriguez J (2016)	1
CBLB	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Ettenberg SA (1999), Lavagna-Sevenier C (1998), Lavagna-Sevenier C (1998), Elly C (1999), Bandyopadhyay S (2010), Vinayagam A (2011), Bisson N (2011), Blagoev B (2003), Rolland T (2014), Huttlin EL (2017)	10
EP300	36	HDAC3	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Kadeppagari RK (2009), Gregoire S (2007), Gregoire S (2007), Sankar N (2008), Sankar N (2008)	5
BCAR1	6	FYN	1	two hybrid, affinity chromatography technology, pull down	Donaldson JC (2000), Manie SN (1997), Manie SN (1997)	3
IL20RA	2	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
PIK3R1	6	ALK	8	pull down	Ren SY (2005)	1
PTPN6	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
SRC	2	KIT	4	unspecified method	Wollberg P (2003)	1
GRB10	4	IGF1R	5	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Vecchione A (2003), Vecchione A (2003), Dey BR (1996), He W (1998), Morrione A (1996), Morrione A (1996), Broussas M (2009)	7
CBLB	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lavagna-Sevenier C (1998), Elly C (1999), Elly C (1999), Alcazar I (2009), Fang D (2001)	5
CRKL	1	SHC1	0	affinity chromatography technology	Chin H (1997)	1
AKT1	1	YWHAG	5	affinity chromatography technology	Klein JB (2005)	1
SOCS1	1	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	He Y (2006), He Y (2006), He Y (2006), Kolliputi N (2009), Kolliputi N (2009)	5
PTGER3	2	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAP3K5	1	DAB2IP	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang H (2007), Xie D (2009), Xie D (2009), Zhang H (2004), Zhang H (2004), Wang H (2015)	6
5175	0	PTPN6	0	pull down, far western blotting, affinity chromatography technology, pull down	Pumphrey NJ (1999), Pumphrey NJ (1999), Hua CT (1998), Hua CT (1998)	4
IGF1R	5	PXN	1	affinity chromatography technology	Manes S (1999)	1
DOK1	2	NCK1	0	unspecified method, affinity chromatography technology	Liu BA (2012), Wick MJ (2001)	2
SYK	3	PXN	1	affinity chromatography technology	Fernandez R (1998)	1
EFNB2	0	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TNFRSF1A	3	SOS1	5	affinity chromatography technology	Kurada BR (2009)	1
ARHGAP17	1	GRB2	2	pull down	Richnau N (2001)	1
SOCS1	1	ABL1	9	affinity chromatography technology	Qiu X (2012)	1
IRS4	2	EGFR	5	unspecified method, affinity chromatography technology	Jones RB (2006), Tong J (2014)	2
WAS	0	LCP2	0	affinity chromatography technology	Krause M (2000)	1
LCK	0	ZAP70	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pelosi M (1999), Thome M (1995), Lupher ML (1996)	3
GAB2	3	CRKL	1	affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology	Crouin C (2001), Crouin C (2001), Crouin C (2001), Schaeper U (2000)	4
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
VAV1	2	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song JS (1996), Ye ZS (1994), Ye ZS (1994), Germani A (1999), Lee IS (1997)	5
HAVCR2	0	PIK3R2	3	affinity chromatography technology	Huttlin EL (2017)	1
NCL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Huddleson JP (2006), Huddleson JP (2006)	2
NCL	1	NPM1	0	affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Li YP (1996), Li YP (1996), Park G (2010), Okuwaki M (2012), Havugimana PC (2012), Yu Y (2006), Huttlin EL (2017)	7
ERBB3	3	ACTA1	1	affinity chromatography technology	Li J (2013)	1
ACTA1	1	ABL1	9	pull down	Hantschel O (2005)	1
ALK	8	PIK3CB	2	affinity chromatography technology	Crockett DK (2004)	1
EZR	8	PTK2	2	pull down	Poullet P (2001)	1
SRC	2	PTPN11	20	enzymatic study	Vogel W (1996)	1
CBL	7	SYK	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Lupher ML (1998), Lupher ML (1998), Bertagnolo V (2001), Melander F (2003), Macglashan D (2004), Rao N (2001), Rao N (2001), Yankee TM (1999), Saci A (2000), Moon KD (2005), Lottin-Divoux S (2006), Grossmann AH (2004), Ota S (2000), Ota S (2000), Panchamoorthy G (1996), Marcilla A (1995), Justa-Schuch D (2016)	17
CHAF1A	1	SQSTM1	0	affinity chromatography technology	Takami Y (2007)	1
APPL1	1	CBL	7	two hybrid	Grossmann A (2015)	1
SHC1	0	FGFR2	6	affinity chromatography technology, pull down, affinity chromatography technology	Schueller AC (2008), Schueller AC (2008), Schueller AC (2008)	3
AXL	4	SRC	2	far western blotting	Braunger J (1997)	1
SOCS1	1	VAV1	2	affinity chromatography technology, affinity chromatography technology	De Sepulveda P (1999), De Sepulveda P (2000)	2
PCBP1	2	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SYNM	3	CBL	7	affinity chromatography technology	Bruzzaniti A (2005)	1
TYRO3	4	PIK3R1	6	two hybrid, affinity chromatography technology	Lan Z (2000), Lan Z (2000)	2
EGFR	5	ZAP70	5	unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
TNFRSF1A	3	KHDRBS1	1	affinity chromatography technology	Pincheira R (2008)	1
SHB	4	VAV1	2	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
NTRK1	1	ARHGAP17	1	affinity chromatography technology	Emdal KB (2015)	1
SHB	4	SRC	2	pull down, affinity chromatography technology	Karlsson T (1995), Karlsson T (1995)	2
ITSN1	5	PDE4D	4	protein complementation assay, affinity chromatography technology	Wong KA (2012), Wong KA (2012)	2
TNIP1	1	TYRO3	4	two hybrid	Yu H (2011)	1
PDGFRA	3	STAT3	0	imaging technique	Chen TC (2014)	1
FGFR1	2	JAK2	1	affinity chromatography technology	Dudka AA (2010)	1
CD247	1	LCK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Munoz P (2003), Munoz P (2003), Yang M (2015)	3
FASLG	0	CRK	0	unspecified method	Voss M (2009)	1
CBLB	3	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
EPHA2	3	GRB2	2	affinity chromatography technology, pull down	Pratt RL (2002), Pratt RL (2002)	2
IL6ST	0	VAV1	2	pull down	Lee IS (1997)	1
EZR	8	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Coene ED (2011), Coene ED (2011), Ertych N (2016)	3
PIK3R1	6	EPOR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology	Shigematsu H (1997), Shigematsu H (1997), Damen JE (1995), Damen JE (1995), Montoye T (2005), Bulut GB (2013)	6
EGFR	5	SH2D2A	2	unspecified method	Jones RB (2006)	1
GNAQ	1	PIK3CA	8	affinity chromatography technology	Ballou LM (2003)	1
IGF1R	5	PTK2	2	affinity chromatography technology	Manes S (1999)	1
GRB10	4	AKT1	1	pull down, enzymatic study	Urschel S (2005), Urschel S (2005)	2
GRB2	2	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, two hybrid	Sieg DJ (2000), Angers-Loustau A (1999), Hildebrand JD (1996), Messina S (2003), Arold ST (2002), Vinayagam A (2011)	6
ESR1	0	NCL	1	affinity chromatography technology, pull down	Tarallo R (2011), Nalvarte I (2010)	2
ITSN1	5	WAS	0	affinity chromatography technology, affinity chromatography technology	Tsyba L (2008), Wang JB (2005)	2
IRS4	2	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fantin VR (1998), Bisson N (2011), Bisson N (2011)	3
CSF2RA	1	PIK3R1	6	affinity chromatography technology	Dhar-Mascareno M (2003)	1
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
ESR1	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Ambrosino C (2010), Ambrosino C (2010), Tarallo R (2011), Nalvarte I (2010)	4
ERBB2	6	PIK3R3	0	unspecified method	Jones RB (2006)	1
EZR	8	FASLG	0	biochemical, affinity chromatography technology	Gajate C (2005), Parlato S (2000)	2
ERBB2	6	SH2D2A	2	unspecified method	Jones RB (2006)	1
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
PTK2	2	EGFR	5	affinity chromatography technology, two hybrid, protein complementation assay	Sieg DJ (2000), Kotlyar M (2015), Petschnigg J (2014)	3
TGFBR1	2	TGFBR2	0	two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, two hybrid, affinity chromatography technology	Kawabata M (1995), Razani B (2001), Yan X (2011), Yan X (2009), Kim SI (2009), Kim SI (2009), Datta PK (2000), Perlman R (2001), Cho W (2015)	9
JAK2	1	STAT3	0	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Ram PA (1997), Manea A (2010), Andl CD (2004), Kamakura S (2004), He K (2013), Kucia-Tran JA (2016), M L (2016)	7
LCK	0	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
RAB5A	0	APPL1	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Miaczynska M (2004), Miaczynska M (2004), Mao X (2006), Zhu G (2007)	4
LCK	0	CBL	7	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Rao N (2002), Tsygankov AY (1996), Reedquist KA (1996), Nervi S (2005)	4
EGFR	5	PLCG2	11	unspecified method, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014)	5
FASLG	0	LCK	0	pull down	Wenzel J (2001)	1
CRK	0	PTTG1	0	two hybrid	Grossmann A (2015)	1
SQSTM1	0	CUL3	17	imaging technique, affinity chromatography technology	Lau A (2010), Mori Y (2015)	2
PIK3R2	3	PIK3R3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
GAB2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down	Lynch DK (2002), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Ren SY (2005), Momose H (2003)	6
IRS1	7	IRS2	6	biochemical	Sun H (2003)	1
HRAS	2	PIK3CD	4	two hybrid	Boettner B (2000)	1
PTPN6	0	SYK	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ganju RK (2000), Dustin LB (1999), Dustin LB (1999)	3
BCAR1	6	NCK1	0	affinity chromatography technology, unspecified method	Okabe S (2002), Liu BA (2012)	2
NCK1	0	CD3E	0	pull down	Gil D (2002)	1
MED28	2	FYN	1	affinity chromatography technology	Lu M (2006)	1
AXL	4	PIK3R1	6	enzymatic study, affinity chromatography technology	Braunger J (1997), Weinger JG (2008)	2
SYK	3	PIK3R2	3	two hybrid	Moon KD (2005)	1
GRB2	2	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, unspecified method, affinity chromatography technology, two hybrid	Lewitzky M (2001), Robinson A (1996), Erdreich-Epstein A (1999), Hendricks-Taylor LR (1997), Asada H (1999), Bandyopadhyay S (2010), Chu J (1998), Berry DM (2002), Brehme M (2009), Rolland T (2014)	10
SH3KBP1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Watanabe S (2000), Watanabe S (2000), Petrelli A (2002), Soubeyran P (2002), Soubeyran P (2002), Szymkiewicz I (2002), Borinstein SC (2000), Schmidt MH (2006), Schmidt MH (2004), Schmidt MH (2004), Verdier F (2002), Verdier F (2002), Feshchenko EA (2004), Chandra V (2010), Niiro H (2012), Feng L (2011), Havrylov S (2009), Zhang J (2009), Zhang J (2009), Ababou A (2009), Le Bras S (2007), Jozic D (2005), Kowanetz K (2004), Kowanetz K (2003), Kowanetz K (2003), Tibaldi EV (2003), Tibaldi EV (2003), Take H (2000), Take H (2000), Schroeder B (2012), Schroeder B (2012), Peruzzi G (2007), Selbach M (2006), Sato S (2013), Taipale M (2014), Taipale M (2014), Diesenberg K (2015), Petrelli A (2002), Huttlin EL (2017)	39
PIK3R1	6	HCST	0	unspecified method	Wu J (1999)	1
CRK	0	PIK3CA	8	affinity chromatography technology	Brehme M (2009)	1
EFNB2	0	PIK3R3	0	affinity chromatography technology	Huttlin EL (2015)	1
SHC1	0	PTK2	2	affinity chromatography technology	Hecker TP (2002)	1
TNFRSF1A	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SRC	2	PXN	1	pull down	Angers-Loustau A (1999)	1
ALK	8	SOCS1	1	affinity chromatography technology	Crockett DK (2004)	1
NCK1	0	ERBB3	3	unspecified method	Jones RB (2006)	1
SOS1	5	ABI1	1	pull down, affinity chromatography technology	Scita G (1999), Scita G (1999)	2
GRB2	2	PXN	1	pull down	Angers-Loustau A (1999)	1
CRK	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Larsson H (1999)	2
ALK	8	JAK2	1	affinity chromatography technology	Crockett DK (2004)	1
NTRK1	1	PTPN11	20	affinity chromatography technology	Emdal KB (2015)	1
BRCA1	7	PDGFRA	3	genetic interference	Shen JP (2017)	1
FAS	2	TNFRSF1A	3	biochemical	Gajate C (2005)	1
ABL1	9	SRC	2	pull down	Yu HH (2001)	1
SOCS6	0	PIK3R2	3	affinity chromatography technology	Krebs DL (2002)	1
SYK	3	NCK1	0	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
CLNK	2	GRB2	2	two hybrid	Grossmann A (2015)	1
EGFR	5	CLNK	2	unspecified method	Jones RB (2006)	1
IRS4	2	NISCH	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sano H (2002), Sano H (2002), Taipale M (2014), Taipale M (2014)	4
FES	2	BCR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lionberger JM (2000), Lionberger JM (2000), Maru Y (1995), Maru Y (1995)	4
STAT3	0	FGFR2	6	affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Dudka AA (2010)	2
JAK2	1	PTPN6	0	affinity chromatography technology, affinity chromatography technology	Jiao H (1996), Wu DW (2000)	2
EP300	36	NFKBIA	0	affinity chromatography technology	Shin DH (2009)	1
PIK3R3	0	PIK3CA	8	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Mothe I (1997), Grossmann A (2015), Hein MY (2015), Huttlin EL (2017)	4
ZAP70	5	LAT	0	enzymatic study, enzymatic study, imaging technique, affinity chromatography technology	Paz PE (2001), Perez-Villar JJ (2002), Houtman JC (2006), Xie JJ (2013)	4
KIT	4	SOCS1	1	two hybrid, affinity chromatography technology	De Sepulveda P (1999), De Sepulveda P (1999)	2
SRC	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, fluorescent resonance energy transfe, imaging technique, imaging technique, imaging technique, pull down, imaging technique, imaging technique, affinity chromatography technology, two hybrid	Migliaccio A (2000), Teo AK (2001), Slentz-Kesler K (2000), Bourdoncle A (2005), Jaber BM (2004), Jaber BM (2004), Ku TK (2007), Cabodi S (2004), Monroe DG (2003), Hitosugi T (2007), Zwart W (2007), Zwart W (2007), Zwart W (2007), Yoshimaru T (2013), Yoshimaru T (2013), Zhang H (2006), Zhang H (2006), Zhang H (2006), Endler A (2012), Endler A (2012)	20
ERBB3	3	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Li J (2013)	3
EGFR	5	RET	3	two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Bhinge K (2017), Bhinge K (2017)	4
IL20RA	2	PIK3CB	2	affinity chromatography technology	Huttlin EL (2017)	1
BCAR1	6	PTK2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Hsia DA (2003), Hildebrand JD (1996), Chellaiah MA (2001), Okabe S (2002), Wang JF (2000), Wu Y (2005), Ponnala S (2011), Cho SY (2002)	9
SHC1	0	TUBA1B	0	affinity chromatography technology	Brehme M (2009)	1
STAT3	0	PIK3R2	3	two hybrid	Grossmann A (2015)	1
SHC1	0	EPHA2	3	affinity chromatography technology, pull down	Pratt RL (2002), Pratt RL (2002)	2
SH2D2A	2	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
SHC1	0	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Lynch DK (2002), van den Akker E (2004)	3
IL6ST	0	PIK3R1	6	affinity chromatography technology	Chung TD (2000)	1
HRAS	2	SH3KBP1	1	affinity chromatography technology	Lito P (2008)	1
ARAF	0	HRAS	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BCAR1	6	ABL1	9	affinity chromatography technology, enzymatic study	Salgia R (1996), Mayer BJ (1995)	2
BCAR1	6	ERBB2	6	affinity chromatography technology	Bisaro B (2016)	1
CBL	7	IGF1R	5	enzymatic study, affinity chromatography technology	Sehat B (2008), Sehat B (2008)	2
TGFBR1	2	EP300	36	affinity chromatography technology, affinity chromatography technology	Mu Y (2011), Mu Y (2011)	2
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
PIK3CA	8	HRAS	2	pull down, two hybrid, pull down	Vargiu P (2004), Li W (2000), Rodriguez-Viciana P (1996)	3
TNFRSF1A	3	FYN	1	biochemical	Legler DF (2003)	1
APPL1	1	CBLB	3	two hybrid	Grossmann A (2015)	1
FGFR1	2	TUBA1B	0	affinity chromatography technology	Vecchione A (2007)	1
ERBB2	6	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
INPP5D	2	BCR	3	affinity chromatography technology	Ruschmann J (2010)	1
EGFR	5	EPHA2	3	affinity chromatography technology	Tong J (2014)	1
DAB2IP	3	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Xie D (2009), Xie D (2009), Dai X (2014)	3
CBL	7	PDGFRA	3	affinity chromatography technology, pull down	Bonita DP (1997), Bonita DP (1997)	2
JAK2	1	SOCS1	1	two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yasukawa H (1999), Dif F (2001), Endo TA (1997), Endo TA (1997), Endo TA (1997), Yasukawa H (1999), Yasukawa H (1999), Pezet A (1999), Ungureanu D (2002), Masuhara M (1997), Ali S (2003), Monni R (2001), Monni R (2001), Piessevaux J (2008), Yu L (2009), Maruoka M (2017)	16
ALK	8	SHC1	0	affinity chromatography technology	Bonvini P (2002)	1
SQSTM1	0	NTRK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wooten MW (2001), Geetha T (2003), Jadhav T (2008), Wooten MW (2008), Wooten MW (2008), Zheng C (2015)	6
HDAC3	5	VHL	0	pull down	Mahon PC (2001)	1
SH2D2A	2	PIK3R1	6	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
TMEM17	0	APPL1	1	bioid	Gupta GD (2015)	1
HTT	14	ZDHHC17	1	two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid, two hybrid	Faber PW (1998), Singaraja RR (2002), Singaraja RR (2002), Singaraja RR (2002), Suter B (2013), Butland SL (2014)	6
FGFR1	2	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Dudka AA (2010), Dudka AA (2010)	3
TGFBR2	0	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ARHGAP32	11	CRKL	1	pull down, affinity chromatography technology	Nakamura T (2002), Nakamura T (2002)	2
PIK3R1	6	ADAM12	1	pull down, affinity chromatography technology, affinity chromatography technology	Kang Q (2001), Kang Q (2001), Kang Q (2001)	3
IGF1R	5	CRKL	1	imaging technique	Chen TC (2014)	1
AKT1	1	NFKBIA	0	affinity chromatography technology	Koul D (2001)	1
NTRK1	1	YWHAG	5	affinity chromatography technology	Emdal KB (2015)	1
CSF1R	0	PIK3R1	6	affinity chromatography technology, imaging technique	Wang Y (1999), Chen TC (2014)	2
FGFR1	2	CRKL	1	affinity chromatography technology	Seo JH (2009)	1
DNM2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Feng H (2012), Feng H (2012)	2
FYN	1	5175	0	affinity chromatography technology	Cicmil M (2000)	1
PIK3CA	8	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sattler M (1997), Sattler M (1997), Chernock RD (2001), Chernock RD (2001), Brehme M (2009)	5
NTRK1	1	ABL1	9	two hybrid, affinity chromatography technology, pull down	Koch A (2000), Yano H (2000), Koch A (2000)	3
SRC	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology	Narita T (2005), Schroeder B (2012)	2
ALK	8	SRC	2	affinity chromatography technology	Ambrogio C (2005)	1
GRB2	2	INPP5D	2	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kavanaugh WM (1996), Kavanaugh WM (1996), de Castro RO (2012), Ho JM (2002)	4
SOS1	5	PTPN6	0	affinity chromatography technology	Kon-Kozlowski M (1996)	1
CBL	7	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vandenbroere I (2003), Prasad NK (2005), De Schutter J (2009), De Schutter J (2009), Brehme M (2009)	5
NTRK1	1	ARHGAP32	11	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Nakamura T (2002), Nakamura T (2002), Nakamura T (2002), Emdal KB (2015)	4
ZDHHC17	1	INPP5D	2	two hybrid	Butland SL (2014)	1
PTPN6	0	LCK	0	enzymatic study, enzymatic study, pull down	Yu CL (2000), Chiang GG (2001), Lorenz U (1994)	3
EPOR	3	CBL	7	affinity chromatography technology	Wakioka T (1999)	1
IRS4	2	ERBB2	6	unspecified method	Jones RB (2006)	1
DOK1	2	VAV1	2	unspecified method	Liu BA (2012)	1
APPL1	1	AKT1	1	affinity chromatography technology, two hybrid, imaging technique	Yang L (2003), Grossmann A (2015), Chen TC (2014)	3
GRB2	2	RET	3	pull down, pull down, affinity chromatography technology, pull down	Borrello MG (1994), Pandey A (1995), Scott RP (2005), Besset V (2000)	4
EP300	36	SIRT1	3	affinity chromatography technology, affinity chromatography technology	Bouras T (2005), Bourguignon LY (2009)	2
SRC	2	PDE4D	4	far western blotting	Beard MB (1999)	1
KIT	4	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zeng S (2005), Brizzi MF (1996), Dong Y (2015)	3
CRKL	1	SOCS1	1	two hybrid	Grossmann A (2015)	1
AKT1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method	Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016)	5
NCK1	0	SOS1	5	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Wunderlich L (1999), Hu Q (1995), Hu Q (1995), Okada S (1996), Okada S (1996), Braverman LE (1999)	6
ABL1	9	ERBB2	6	unspecified method	Jones RB (2006)	1
BCR	3	KIT	4	affinity chromatography technology, affinity chromatography technology, imaging technique	Hallek M (1996), Hallek M (1996), Chen TC (2014)	3
SRC	2	ERBB3	3	unspecified method	Jones RB (2006)	1
CD247	1	ZAP70	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mustelin T (1995), Wang HY (2001), La Face DM (1997), Huang H (2010), Huang H (2010), Hubert P (1996), Yang M (2015)	7
CBL	7	SOS1	5	affinity chromatography technology	Wang Y (1999)	1
ERBB3	3	PTPN6	0	two hybrid	Yao Z (2017)	1
INPP5D	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dunant NM (2000), Dunant NM (2000), Wisniewski D (1999), Leitges M (2002), Damen JE (1996), Damen JE (1996), March ME (2000), Hunter MG (2004), Ho JM (2002)	9
EGFR	5	ARHGAP1	0	affinity chromatography technology	Tong J (2014)	1
SOCS6	0	PIK3R3	0	affinity chromatography technology, two hybrid	Huttlin EL (2015), Grossmann A (2015)	2
ZAP70	5	SHC1	0	affinity chromatography technology, enzymatic study, affinity chromatography technology	Pacini S (1998), Pacini S (1998), Jin HS (2013)	3
CRK	0	WEE1	2	affinity chromatography technology	Smith JJ (2002)	1
PLCG2	11	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Boudot C (2002)	2
TNFRSF1A	3	DAB2IP	3	affinity chromatography technology	Zhang H (2004)	1
CBL	7	PTK2	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Schmidt MH (2003), Sekine Y (2007)	3
IGF1R	5	ESR1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Santen RJ (2005), Song RX (2004), Yoshimaru T (2013)	3
AXL	4	GRB2	2	far western blotting, affinity chromatography technology, pull down	Braunger J (1997), Weinger JG (2008), Weinger JG (2008)	3
IRS1	7	PIK3CA	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tzatsos A (2006), Bazuine M (2003), Whiteman EL (2003), Kuchay S (2013)	4
NTRK1	1	RET	3	affinity chromatography technology	Emdal KB (2015)	1
PIK3R1	6	VHL	0	genetic interference	Shen JP (2017)	1
ITSN1	5	SH3KBP1	1	affinity chromatography technology	Nikolaienko O (2009)	1
FYN	1	FGFR2	6	affinity chromatography technology	Kaabeche K (2004)	1
ERBB3	3	ZAP70	5	unspecified method	Jones RB (2006)	1
PIK3R1	6	TUBA1B	0	affinity chromatography technology, pull down	Kapeller R (1995), Kapeller R (1995)	2
PDGFRA	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, imaging technique	Zhu MJ (2007), Zhu MJ (2007), Chen TC (2014)	3
ABL1	9	GRB2	2	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Warmuth M (1997), Ren R (1994), Ren R (1994), Patel H (2006), Johnson KJ (2009), Gaston I (2004), Gaston I (2004), Brehme M (2009), Brehme M (2009), Chen R (2013), Feller SM (1994)	11
GAB1	3	SHC1	0	affinity chromatography technology, far western blotting, affinity chromatography technology	Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004)	3
CUL3	17	GRB2	2	affinity chromatography technology	Bennett EJ (2010)	1
RET	3	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Yuan ZL (2004), Hwang JH (2003), Schuringa JJ (2001), Chen TC (2014)	4
ABL1	9	GRB10	4	pull down	Frantz JD (1997)	1
PTK2	2	PIK3R1	6	affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guinebault C (1995), Guinebault C (1995), Lee DY (2010), Reddy MA (2000), Reiske HR (2000)	5
TNFRSF1A	3	PIK3R1	6	affinity chromatography technology	Pincheira R (2008)	1
ABL1	9	NFKBIA	0	affinity chromatography technology, pull down	Kawai H (2002), Kawai H (2002)	2
LTK	2	CBL	7	enzymatic study	Ueno H (1997)	1
FGFR1	2	VAV1	2	unspecified method	Liu BA (2012)	1
WAS	0	EGFR	5	affinity chromatography technology, affinity chromatography technology	She HY (1997), She HY (1997)	2
FGFR1	2	CTNNB1	30	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Boscher C (2008), Boscher C (2008)	3
VAV1	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Bertagnolo V (1998), Bertagnolo V (1998), Bertagnolo V (1998), Shigematsu H (1997), Shigematsu H (1997), Shigematsu H (1997)	6
FGFR1	2	PIK3R2	3	two hybrid	Hu Y (2004)	1
TNIP1	1	PIK3R1	6	affinity chromatography technology	Wang HB (2007)	1
SHC1	0	INPPL1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wisniewski D (1999), Wisniewski D (1999), Pesesse X (2001), Habib T (1998), Brehme M (2009), Brehme M (2009)	6
EGFR	5	PIK3CB	2	affinity chromatography technology	Foerster S (2013)	1
PIK3R1	6	SOS1	5	imaging technique	Chen TC (2014)	1
TNFRSF1A	3	CBL	7	affinity chromatography technology	Narita T (2005)	1
FGFR1	2	NCK1	0	unspecified method	Liu BA (2012)	1
DOK1	2	PIK3R1	6	pull down, unspecified method	van Dijk TB (2000), Liu BA (2012)	2
RET	3	DOK1	2	two hybrid, pull down, affinity chromatography technology	Murakami H (2002), Murakami H (2002), Murakami H (2002)	3
SOS1	5	HRAS	2	x-ray crystallography, x-ray crystallography, affinity chromatography technology	Margarit SM (2003), Boriack-Sjodin PA (1998), Ji H (2016)	3
SYK	3	CD3E	0	pull down	Bu JY (1995)	1
ALK	8	IRS4	2	affinity chromatography technology	Crockett DK (2004)	1
PTPRK	1	PIK3R1	6	bioid	St-Denis N (2016)	1
EGFR	5	PDGFRA	3	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
ZAP70	5	CD3E	0	pull down, affinity chromatography technology	Bu JY (1995), Hubert P (1996)	2
SHC1	0	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Ota S (1998), Larsson H (1999)	4
EPHA2	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIK3R1	6	CD247	1	affinity chromatography technology	Fang D (2001)	1
VAV1	2	EPOR	3	affinity chromatography technology	Shigematsu H (1997)	1
PTPN11	20	PTPN6	0	affinity chromatography technology	Li X (2016)	1
PIK3CB	2	PIK3R1	6	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique	Hu P (1994), Havugimana PC (2012), Sun M (2010), Wan C (2015), Hein MY (2015), Chen TC (2014)	6
FGFR1	2	RAB5A	0	affinity chromatography technology	Vecchione A (2007)	1
PIK3R1	6	NFKBIA	0	pull down	Beraud C (1999)	1
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
CBL	7	ITSN1	5	far western blotting, two hybrid, affinity chromatography technology, affinity chromatography technology	Martin NP (2006), Thalappilly S (2008), Dergai M (2011), Tsyba L (2008)	4
BCR	3	CRKL	1	affinity chromatography technology, two hybrid, two hybrid, far western blotting, affinity chromatography technology	Heaney C (1997), Heaney C (1997), Kolibaba KS (1999), Kolibaba KS (1999), Million RP (2004)	5
GRB2	2	TNFRSF1A	3	affinity chromatography technology, affinity chromatography technology	Hildt E (1999), Kurada BR (2009)	2
SRC	2	PTPN6	0	enzymatic study	Frank C (2004)	1
5175	0	CTNNB1	30	affinity chromatography technology, imaging technique	Ilan N (2000), Chen TC (2014)	2
NLGN3	3	TGFBR1	2	affinity chromatography technology	Hein MY (2015)	1
EFNB2	0	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FYN	1	VAV1	2	affinity chromatography technology, two hybrid	Michel F (1998), Tartare-Deckert S (2001)	2
NCK1	0	ABL1	9	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Miyoshi-Akiyama T (2001), Ren R (1994), Ren R (1994), Wunderlich L (1999), Adler CE (2000)	5
CRK	0	PDGFRB	8	affinity chromatography technology, pull down	Matsumoto T (2000), Matsumoto T (2000)	2
CTNNB1	30	EP300	36	genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, genetic interference, affinity chromatography technology	Kennell JA (2003), Sun Y (2000), Sun Y (2000), Sun Y (2000), Saegusa M (2005), Daniels DL (2002), Levy L (2004), Labalette C (2004), Lee YH (2006), Zhao Y (2016)	10
BCAR1	6	PXN	1	affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Chellaiah MA (2001)	2
EGFR	5	LAT	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
PIK3R2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Huttlin EL (2015), Huttlin EL (2017)	3
GRB2	2	ARHGAP32	11	two hybrid	Bandyopadhyay S (2010)	1
SOCS6	0	KIT	4	affinity chromatography technology, enzymatic study, x-ray crystallography	Zadjali F (2011), Zadjali F (2011), Zadjali F (2011)	3
BCAR1	6	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Zhou B (2004), Di Stefano P (2004), Hsia DA (2003), Hsia DA (2003), Gu J (2001), Garton AJ (1999), Angers-Loustau A (1999), Qiu W (1998), Blaukat A (1999), Wang JF (2000), Holcomb M (2006), Wu Y (2005), Cho SY (2000), Modzelewska K (2006), Modzelewska K (2006), Brehme M (2009), Cho SY (2002), Cho SY (2002), Mielenz D (2001), Peterson ME (2008), Liu BA (2012), Larsson H (1999)	22
MAPT	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Babu JR (2005), Babu JR (2005), Rui YN (2015)	3
NTRK2	10	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Geetha T (2003), Jadhav T (2008)	2
PDGFRB	8	CBLB	3	affinity chromatography technology	Rorsman C (2016)	1
DOK1	2	ABL1	9	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	van Dijk TB (2000), Yamanashi Y (1997), Yamanashi Y (1997), Johnson KJ (2009), Liu BA (2012), Bhat A (1998), Bhat A (1998), Bhat A (1998), Kashige N (2000)	9
SRC	2	PROM1	2	enzymatic study	Wei Y (2013)	1
CRK	0	SHB	4	affinity chromatography technology	Lu L (2000)	1
CBL	7	BCR	3	pull down, pull down, affinity chromatography technology, enzymatic study	Gaston I (2004), Panchamoorthy G (1996), Brehme M (2009), Tsukahara F (2010)	4
FYN	1	LAT	0	enzymatic study	Jiang Y (2007)	1
CSF1R	0	SRC	2	affinity chromatography technology	Courtneidge SA (1993)	1
EZR	8	ERBB2	6	fluorescent resonance energy transfe, imaging technique	Asp N (2016), Asp N (2016)	2
ITSN1	5	CBLB	3	affinity chromatography technology	Tsyba L (2008)	1
IGF1R	5	PIK3R3	0	pull down, affinity chromatography technology, imaging technique	Mothe I (1997), Mothe I (1997), Chen TC (2014)	3
DNM2	2	SH3KBP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Schroeder B (2010), Schroeder B (2010), Havrylov S (2009), Wan C (2015)	4
ESR1	0	ERBB2	6	affinity chromatography technology	Yang Z (2004)	1
CRKL	1	IRS4	2	pull down	Koval AP (1998)	1
SHB	4	GRB2	2	affinity chromatography technology	Welsh M (1998)	1
ABL1	9	PIK3R1	6	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Kapeller R (1994), Ren SY (2005), Ren SY (2005), Ren SY (2005), Brehme M (2009)	5
EPHA2	3	PTPN11	20	affinity chromatography technology, two hybrid	Miao H (2000), Yao Z (2017)	2
ERBB3	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hellyer NJ (2001), Lin J (1999), Crovello CS (1998), Graus-Porta D (1997), Jones RB (2006), Li J (2013), Servidei T (2008), Servidei T (2008), Ritch PS (2005), Tang X (2002)	10
CRKL	1	INPP5D	2	pull down, affinity chromatography technology	Arai A (2001), Arai A (2001)	2
PIK3R1	6	KHDRBS1	1	affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Sanchez-Margalet V (2001), Shen Z (1999), Shen Z (1999), Asbach B (2012), Asbach B (2012), Asbach B (2012), Sung CK (1994), Sung CK (1994)	8
CUL3	17	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
CRK	0	YWHAG	5	affinity chromatography technology	Brehme M (2009)	1
ERBB2	6	PLCG2	11	unspecified method, imaging technique	Jones RB (2006), Chen TC (2014)	2
IRS1	7	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Rui L (2002), Li JY (2007)	2
TGFBR1	2	APPL1	1	affinity chromatography technology, pull down, imaging technique	Song J (2016), Song J (2016), Song J (2016)	3
BRCA1	7	PCBP1	2	affinity chromatography technology	Ertych N (2016)	1
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
ARHGAP17	1	ABL1	9	pull down	Richnau N (2001)	1
SYK	3	VAV1	2	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Deckert M (1996), Deckert M (1996), Deckert M (1996), Song JS (1996), Bertagnolo V (2001), Bertagnolo V (2001), Tartare-Deckert S (2001)	7
AKT1	1	GNB1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Klein JB (2005), Xiong Y (2009), Xiong Y (2009)	3
IRS2	6	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Whiteman EL (2003), Fukushima T (2015)	2
SHB	4	LCP2	0	affinity chromatography technology, pull down	Lindholm CK (2002), Lindholm CK (2002)	2
IGF1R	5	ERBB2	6	affinity chromatography technology	Riedemann J (2007)	1
NPM1	0	PCBP1	2	affinity chromatography technology	Chen R (2013)	1
RNF19B	0	PIK3CB	2	affinity chromatography technology	Huttlin EL (2017)	1
ABL1	9	CBLB	3	affinity chromatography technology	Brehme M (2009)	1
TNFRSF1A	3	SRC	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Narita T (2005), Pincheira R (2008), Darnay BG (1997)	3
NTRK1	1	PDGFRA	3	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	CBLB	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Schulze WX (2006), Ettenberg SA (1999), Davies GC (2006), Davies GC (2006), Tong J (2009), Ettenberg SA (2001), Tong J (2008), Levkowitz G (1999), Tong J (2014)	9
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
FYN	1	SH3KBP1	1	affinity chromatography technology	Narita T (2005)	1
CRK	0	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
ERBB2	6	IRS1	7	unspecified method	Jones RB (2006)	1
ABL1	9	BRCA1	7	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, fluorescent resonance energy transfe	Foray N (2002), Foray N (2002), Foray N (2002), Foray N (2002), Foray N (2002), Morell M (2007)	6
EGFR	5	ESR1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hitosugi T (2007), Hitosugi T (2007), Yao Z (2017)	3
EP300	36	MAPT	1	enzymatic study	Min SW (2010)	1
SHC1	0	RET	3	affinity chromatography technology, pull down, affinity chromatography technology	Arighi E (1997), Arighi E (1997), Borrello MG (1994)	3
PIK3R1	6	TTR	0	two hybrid	Wang J (2008)	1
PIK3R1	6	PLCG2	11	imaging technique	Chen TC (2014)	1
PIK3R1	6	EZR	8	affinity chromatography technology, pull down	Gautreau A (1999), Gautreau A (1999)	2
TGFBR2	0	PIK3R2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Krymskaya VP (1997), Huttlin EL (2015), Huttlin EL (2017)	3
SIRT1	3	ESR1	0	affinity chromatography technology	Elangovan S (2011)	1
HTT	14	PIK3R1	6	two hybrid	Suter B (2013)	1
ERBB3	3	TUBA1B	0	affinity chromatography technology	Li J (2013)	1
CTNNB1	30	CBL	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Chitalia V (2013), Chitalia V (2013), Chitalia V (2013), Shivanna S (2015)	4
NTRK1	1	PIK3CA	8	affinity chromatography technology	Emdal KB (2015)	1
KIT	4	PTPN6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Kozlowski M (1998), Kozlowski M (1998), Kozlowski M (1998), Yi T (1993), Yi T (1993)	5
GRB2	2	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Million RP (2004), Lynch DK (2002), Zhao C (1999), Zhao C (1999), Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Rolland T (2014), Huttlin EL (2017), Yu WM (2006), Yu WM (2006)	11
GRB2	2	SYK	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ganju RK (2000), Saci A (2002), de Castro RO (2012), de Castro RO (2012)	4
DOK1	2	CRK	0	unspecified method	Liu BA (2012)	1
ESR1	0	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Cabodi S (2004), Robinson LJ (2009)	2
YWHAG	5	IRS2	6	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
WEE1	2	PCBP1	2	affinity chromatography technology	So J (2015)	1
PIK3R1	6	PDE4D	4	far western blotting	Beard MB (1999)	1
SOS1	5	FYN	1	pull down	Park C (1998)	1
ERBB2	6	FER	1	unspecified method	Jones RB (2006)	1
SYK	3	LCP2	0	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
PIK3R1	6	WEE1	2	genetic interference	Shen JP (2017)	1
CD3E	0	CD247	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Munoz P (2003), Munoz P (2003), Chen TC (2014)	3
SRC	2	ARHGAP1	0	pull down	Barfod ET (1993)	1
PIK3R1	6	CD28	0	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pages F (1996), Pages F (1996), Alcazar I (2009), Fang D (2001)	4
ARAF	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ABI1	1	PIK3R1	6	unspecified method, affinity chromatography technology	Dubielecka PM (2010), Dubielecka PM (2010)	2
DNM2	2	PIK3R1	6	affinity chromatography technology	Feng H (2012)	1
STAT3	0	SYK	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
YWHAG	5	ABL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Raina D (2006), Yoshida K (2005), Yoshida K (2005), So J (2015)	4
PIK3CB	2	GNB1	4	affinity chromatography technology	Ye Y (2016)	1
FYN	1	FAS	2	affinity chromatography technology	Atkinson EA (1996)	1
EGFR	5	LCP2	0	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
TNFRSF1A	3	PIK3CA	8	affinity chromatography technology	Narita T (2005)	1
CD28	0	VAV1	2	affinity chromatography technology	Klasen S (1998)	1
CUL3	17	KHDRBS1	1	affinity chromatography technology	Bennett EJ (2010)	1
SYN1	1	CRK	0	affinity chromatography technology	Onofri F (2000)	1
FGFR1	2	PLCG2	11	affinity chromatography technology	Vecchione A (2007)	1
SOCS1	1	FLT3	5	affinity chromatography technology	De Sepulveda P (1999)	1
PIK3R2	3	BCR	3	affinity chromatography technology	Brehme M (2009)	1
ESR1	0	IRS2	6	affinity chromatography technology, affinity chromatography technology	Morelli C (2003), Morelli C (2003)	2
ESR1	0	PRMT2	3	pull down, affinity chromatography technology	Qi C (2002), Qi C (2002)	2
TGFBR2	0	FGFR1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AKT1	1	MAPT	1	enzymatic study	Sadik G (2009)	1
SH3KBP1	1	KIT	4	affinity chromatography technology	Szymkiewicz I (2002)	1
PIK3R1	6	CXCL2	0	two hybrid	Wang J (2008)	1
IRS4	2	YWHAG	5	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
IRS1	7	PIK3R2	3	affinity chromatography technology	Kuchay S (2013)	1
EGFR	5	MAPT	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
CD40	3	PIK3CA	8	affinity chromatography technology	Deregibus MC (2003)	1
NCK1	0	ARHGAP32	11	pull down, affinity chromatography technology	Zhao C (2003), Zhao C (2003)	2
PTPN6	0	EPOR	3	affinity chromatography technology, pull down	Klingmueller U (1995), Klingmueller U (1995)	2
PTPN6	0	LCP2	0	pull down, pull down, affinity chromatography technology	Binstadt BA (1998), Mizuno K (1996), Mizuno K (1996)	3
DLX2	0	PIK3R1	6	two hybrid	Wang J (2011)	1
SH2D2A	2	PIK3R3	0	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
LCP2	0	SHC1	0	affinity chromatography technology	Chu J (1998)	1
IRS2	6	PIK3R3	0	affinity chromatography technology, affinity chromatography technology	Xia X (1999), Huttlin EL (2017)	2
FCGR2A	0	PIK3R1	6	affinity chromatography technology, pull down	Chacko GW (1996), Ibarrola I (1997)	2
EPOR	3	INPP5D	2	protein complementation assay	Montoye T (2005)	1
EGFR	5	FES	2	unspecified method	Jones RB (2006)	1
RAB5A	0	SH3KBP1	1	affinity chromatography technology	Schroeder B (2012)	1
FYN	1	SOCS1	1	pull down	De Sepulveda P (1999)	1
MYO16	4	PIK3R1	6	pull down	Yokoyama K (2011)	1
CRKL	1	ABL1	9	affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heaney C (1997), Heaney C (1997), Heaney C (1997), Ren R (1994), Ren R (1994), Kyono WT (1998), Ren R (1994), Patel H (2006), Johnson KJ (2009), Ribon V (1996), Senechal K (1998), Nishihara T (2003), Peterson ME (2008)	13
GAB2	3	PTPN6	0	affinity chromatography technology	Yu WM (2002)	1
ERBB3	3	CRKL	1	unspecified method	Jones RB (2006)	1
DEFA5	1	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
TMEM17	0	EFNB2	0	bioid	Gupta GD (2015)	1
ERBB2	6	PIK3R2	3	pull down, unspecified method	Gout I (1992), Jones RB (2006)	2
RAB5A	0	PIK3R1	6	affinity chromatography technology	Chamberlain MD (2004)	1
PXN	1	LCK	0	affinity chromatography technology	Ostergaard HL (1998)	1
FGFR1	2	ACTA1	1	affinity chromatography technology	Vecchione A (2007)	1
ERBB3	3	PIK3R3	0	unspecified method, affinity chromatography technology	Jones RB (2006), Li J (2013)	2
GRB2	2	DOK1	2	affinity chromatography technology	Kepley CL (2004)	1
FYN	1	CSF1R	0	pull down, pull down, affinity chromatography technology	Courtneidge SA (1993), Courtneidge SA (1993), Courtneidge SA (1993)	3
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
CBL	7	CD247	1	affinity chromatography technology, affinity chromatography technology	Wang HY (2001), Wang HY (2001)	2
PDGFRA	3	TGFBR2	0	two hybrid	Wang J (2011)	1
EPOR	3	PTPN11	20	affinity chromatography technology, pull down	Tauchi T (1996), Tauchi T (1995)	2
NTRK1	1	DAB2IP	3	affinity chromatography technology	Emdal KB (2015)	1
ERBB2	6	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTPRK	1	CTNNB1	30	pull down, affinity chromatography technology	Fuchs M (1996), Fuchs M (1996)	2
AKT1	1	NPM1	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Lee SB (2008), Lee SB (2008), Lee SB (2008), Lee SB (2008)	4
DEFA5	1	PTPRK	1	affinity chromatography technology	Huttlin EL (2017)	1
GRB10	4	IRS1	7	pull down, affinity chromatography technology	Hansen H (1996), Deng Y (2003)	2
CSF1R	0	PIK3R2	3	pull down	Gout I (1992)	1
SIRT1	3	PIK3R1	6	affinity chromatography technology	Froejdoe S (2011)	1
KIT	4	JAK2	1	affinity chromatography technology	Brizzi MF (1994)	1
HDAC3	5	ESR1	0	imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Liu XF (2004), Zhu P (2006), Nalvarte I (2010), Han SJ (2016)	4
PIK3CA	8	RASD2	1	pull down	Vargiu P (2004)	1
IRS1	7	AKT1	1	affinity chromatography technology, enzymatic study	Paz K (1999), Luo M (2007)	2
LAT	0	PLCG2	11	fluorescent resonance energy transfe, affinity chromatography technology	Matalon O (2016), Matalon O (2016)	2
TLR3	2	PIK3R1	6	affinity chromatography technology	Sarkar SN (2004)	1
SYK	3	SH2D2A	2	two hybrid	Rolland T (2014)	1
LCP2	0	PIK3R1	6	two hybrid, affinity chromatography technology	Shim EK (2004), Shim EK (2004)	2
ARAF	0	EPHA2	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MED28	2	GRB2	2	affinity chromatography technology, pull down	Wiederhold T (2004), Wiederhold T (2004)	2
EGFR	5	LTK	2	pull down, affinity chromatography technology	Ueno H (1995), Ueno H (1995)	2
GRB2	2	PIK3R2	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
JAK2	1	IRS1	7	enzymatic study, affinity chromatography technology	Gual P (1998), Kawazoe Y (2001)	2
FGFR1	2	PIK3R1	6	imaging technique, two hybrid, pull down	Chen TC (2014), Hu Y (2004), Shi E (1993)	3
BRCA1	7	ESR1	0	imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Zheng L (2001), Fan S (2001), Fan S (2001), Kawai H (2002), Fan S (2002), Fan S (2002), Nakuci E (2006), Wang C (2005), Wang C (2005), Dizin E (2010), Dizin E (2010), Ma Y (2010), Ma Y (2010), Fan S (2001), Ma YX (2005), Ma YX (2005), Ma YX (2005), Ma Y (2007), Ma Y (2007), Kawai H (2002), Jung YS (2014), Kawai H (2002), Kawai H (2002)	23
ALK	8	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ambrogio C (2005), Ambrogio C (2005), Ambrogio C (2005)	3
SHB	4	FGFR1	2	pull down, affinity chromatography technology	Karlsson T (1995), Karlsson T (1995)	2
PTK2	2	CRK	0	affinity chromatography technology, pull down, two hybrid	Hsia DA (2003), Angers-Loustau A (1999), Grossmann A (2015)	3
TMEM17	0	SQSTM1	0	bioid	Gupta GD (2015)	1
INPP5D	2	CBL	7	affinity chromatography technology	Bao M (2012)	1
DNM2	2	SRC	2	pull down	Solomaha E (2005)	1
EGFR	5	WDR26	6	affinity chromatography technology	Foerster S (2013)	1
NTRK1	1	SOS1	5	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	CTNNB1	30	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Schroeder JA (2002), Takahashi K (1997), Li J (2013)	4
CRK	0	PXN	1	pull down, affinity chromatography technology	Angers-Loustau A (1999), Abassi YA (2002)	2
FLT1	4	CBL	7	affinity chromatography technology	Raikwar NS (2014)	1
ESR1	0	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Simoncini T (2000), Yoshimaru T (2013)	2
SIRT1	3	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sundaresan NR (2011), Sundaresan NR (2011), Sundaresan NR (2011)	3
FYN	1	JAK2	1	affinity chromatography technology, pull down	Sayeski PP (1999), Sayeski PP (1999)	2
FYN	1	PDE4D	4	far western blotting	Beard MB (1999)	1
VSIG4	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FER	1	EGFR	5	affinity chromatography technology, affinity chromatography technology	Kim L (1995), Tong J (2008)	2
EP300	36	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2011), Roe JS (2011), Ji W (2014), Chen K (2015)	5
NTRK1	1	BCR	3	affinity chromatography technology	Emdal KB (2015)	1
HOXA1	4	PIK3R1	6	two hybrid	Wang J (2011)	1
DNM2	2	GRB2	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Solomaha E (2005), Brehme M (2009), Bisson N (2011), Elhamdani A (2006), Wang J (2011), Huttlin EL (2017)	6
ESR1	0	STAT3	0	affinity chromatography technology	Wang LH (2001)	1
NTRK1	1	WDR26	6	affinity chromatography technology	Emdal KB (2015)	1
EP300	36	NPM1	0	enzymatic study	Swaminathan V (2005)	1
EGFR	5	GAB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, enzymatic study, affinity chromatography technology	Kameda H (2001), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Lehr S (1999), Mueller KL (2012)	6
PDGFRA	3	GRB2	2	affinity chromatography technology, affinity chromatography technology	Bazenet CE (1996), Severe N (2011)	2
ZDHHC17	1	PDE4D	4	two hybrid, affinity chromatography technology	Butland SL (2014), Butland SL (2014)	2
ARHGAP32	11	SRC	2	pull down, affinity chromatography technology	Moon SY (2003), Moon SY (2003)	2
SHC1	0	SRC	2	pull down	Schueller AC (2008)	1
INPP5D	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu L (1997), Chernock RD (2001), Chernock RD (2001)	3
SIRT1	3	STAT3	0	affinity chromatography technology	Lin Z (2012)	1
ERBB2	6	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid	Schulze WX (2006), Wong L (1999), Olayioye MA (1998), Crovello CS (1998), Jones RB (2006), Yao Z (2017)	6
FCGR2A	0	SYK	3	pull down, affinity chromatography technology	Ibarrola I (1997), Kim MK (2001)	2
PIK3CA	8	EGFR	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CD7	0	NFKBIA	0	two hybrid	Wang J (2011)	1
CTNNB1	30	PIK3R1	6	pull down, imaging technique	Espada J (1999), Chen TC (2014)	2
LCK	0	KIT	4	affinity chromatography technology	Krystal GW (1998)	1
ZDHHC17	1	PIK3R1	6	two hybrid, affinity chromatography technology	Butland SL (2014), Butland SL (2014)	2
ZAP70	5	GRB2	2	affinity chromatography technology, affinity chromatography technology	Nel AE (1995), Jin HS (2013)	2
GNB1	4	FYN	1	affinity chromatography technology	Knezevic N (2009)	1
BCAR1	6	CBL	7	affinity chromatography technology	Sawasdikosol S (1996)	1
ARHGAP17	1	SRC	2	pull down	Richnau N (2001)	1
SNX32	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
GRB2	2	NTRK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Song C (2002), MacDonald JI (2000), Emdal KB (2015), Emdal KB (2015)	4
GAB2	3	LAT	0	affinity chromatography technology	Yamasaki S (2001)	1
EGFR	5	IRS2	6	affinity chromatography technology	Tong J (2008)	1
IGF1R	5	STAT3	0	imaging technique	Chen TC (2014)	1
VHL	0	JAK2	1	affinity chromatography technology, affinity chromatography technology	Russell RC (2011), Russell RC (2011)	2
HTT	14	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Filimonenko M (2010), Zhou L (2014), Rui YN (2015), Rui YN (2015)	4
TMEM17	0	PIK3R1	6	bioid	Gupta GD (2015)	1
GRB10	4	IRS2	6	affinity chromatography technology, affinity chromatography technology	Deng Y (2003), Warren KJ (2016)	2
PIK3CA	8	AKT1	1	affinity chromatography technology, protein complementation assay, affinity chromatography technology, enzymatic study	Mitra S (2011), Miao B (2010), Xiong Y (2009), Akil H (2015)	4
EGFR	5	SYK	3	unspecified method	Jones RB (2006)	1
BCAR1	6	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Salgia R (1996), Salgia R (1996), Astier A (1997), Peterson ME (2008), Liu BA (2012)	5
CSF1R	0	PIK3CA	8	pull down, two hybrid	Mancini A (1997), Mancini A (1997)	2
ABL1	9	MAPT	1	enzymatic study, enzymatic study, affinity chromatography technology	Lebouvier T (2008), Derkinderen P (2005), Derkinderen P (2005)	3
FER	1	CTNNB1	30	enzymatic study	Piedra J (2003)	1
LAT	0	CD247	1	affinity chromatography technology	Munoz P (2003)	1
PDGFRB	8	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Farooqui T (2000), Chamberlain MD (2004), Ren SY (2005), Huttlin EL (2017)	4
CBL	7	LCP2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Erdreich-Epstein A (1999), Chu J (1998), Shen M (2009)	4
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
CRK	0	CBLB	3	affinity chromatography technology, two hybrid, two hybrid	Brehme M (2009), Grossmann A (2015), Grossmann A (2015)	3
FGFR1	2	AKT1	1	affinity chromatography technology, affinity chromatography technology	Hu F (2016), Hu F (2016)	2
FASLG	0	TNFRSF1A	3	biochemical, affinity chromatography technology	Gajate C (2005), Legler DF (2003)	2
CRKL	1	EPOR	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Chin H (1997), Arai A (2001), Arai A (2001), Barber DL (1997)	4
FAS	2	FASLG	0	biochemical, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Gajate C (2005), Micheau O (2003), Starling GC (1997), Schneider P (1997), Legler DF (2003), Tao RH (2011), Chen TC (2014)	7
PIK3R1	6	EP300	36	affinity chromatography technology	Song L (2011)	1
STAT3	0	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakashima K (1999), Nakashima K (1999), Ray S (2002), Ray S (2002), Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Wang R (2005), Gray MJ (2005), Hou T (2008), Kotla S (2015)	11
IL6ST	0	ERBB3	3	affinity chromatography technology	Grant SL (2002)	1
CBLB	3	KIT	4	affinity chromatography technology	Szymkiewicz I (2002)	1
GRB2	2	PDGFRB	8	pull down, pull down, affinity chromatography technology	Arvidsson AK (1994), Tang J (1997), Braverman LE (1999)	3
EFNB2	0	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
5175	0	PIK3R1	6	affinity chromatography technology	Pellegatta F (1998)	1
PTK2	2	EPHA2	3	affinity chromatography technology	Miao H (2000)	1
BRCA1	7	WEE1	2	genetic interference	Shen JP (2017)	1
CRK	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, two hybrid	Gesbert F (1998), Husson H (1997), Ingham RJ (1996), Ingham RJ (1996), Delehanty LL (2003), Garcia-Guzman M (2000), Garcia-Guzman M (2000), Barber DL (1997), Buday L (1996), Sawasdikosol S (1996), Sawasdikosol S (1996), Thien CB (1997), van Leeuwen JE (1999), Ribon V (1996), Lottin-Divoux S (2006), Reedquist KA (1996), Brehme M (2009), Brehme M (2009), Ota S (1998), Peterson ME (2008), Liu BA (2012), Fukazawa T (1996), Umehara H (2002), Grossmann A (2015)	24
IL20RA	2	PIK3CA	8	affinity chromatography technology	Huttlin EL (2017)	1
INPPL1	6	TUBA1B	0	affinity chromatography technology	Brehme M (2009)	1
PLCG2	11	PTTG1	0	two hybrid	Grossmann A (2015)	1
CRK	0	IRS4	2	affinity chromatography technology, pull down	Karas M (2001), Koval AP (1998)	2
PRMT2	3	PIK3R1	6	affinity chromatography technology	Huttlin EL (2015)	1
RXRA	1	HDAC3	5	pull down	Franco PJ (2003)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
PIK3R1	6	EPN1	4	affinity chromatography technology	Bulut GB (2013)	1
INPPL1	6	PIK3R2	3	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009)	2
INPP5D	2	DOK1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dunant NM (2000), Dunant NM (2000), van Dijk TB (2000), Kepley CL (2004)	4
ERBB3	3	VAV1	2	unspecified method	Jones RB (2006)	1
NPM1	0	PIK3R1	6	affinity chromatography technology	Crockett DK (2004)	1
SRC	2	MAPT	1	enzymatic study	Bhaskar K (2005)	1
SYK	3	LAT	0	enzymatic study	Paz PE (2001)	1
PDGFRB	8	PTPN11	20	two hybrid, pull down	Keilhack H (2001), Lechleider RJ (1993)	2
APPL1	1	PIK3CA	8	imaging technique	Chen TC (2014)	1
PIK3R1	6	ALOX5	1	affinity chromatography technology, affinity chromatography technology	Ha YJ (2011), Ha YJ (2011)	2
CUL3	17	KBTBD2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Zhang Z (2016), Huttlin EL (2017)	3
INPPL1	6	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Brehme M (2009), Bisson N (2011)	4
CCL14	1	PIK3R1	6	two hybrid	Wang J (2011)	1
PIK3R3	0	PIK3CB	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Huttlin EL (2017)	2
WAS	0	CBL	7	affinity chromatography technology	Watanabe Y (2013)	1
MED28	2	PIK3R1	6	affinity chromatography technology	Lu M (2006)	1
BCR	3	PIK3R1	6	far western blotting	Weinger JG (2008)	1
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
SRC	2	HDAC3	5	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Longworth MS (2006), Longworth MS (2006), Longworth MS (2006), Matteucci E (2007)	4
GSPT1	3	PIK3R1	6	two hybrid	Wang J (2011)	1
PDGFRA	3	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FYN	1	PIK3R2	3	pull down	Gout I (1992)	1
KHDRBS1	1	PIK3R3	0	two hybrid	Wang J (2011)	1
GRB2	2	PIK3R3	0	affinity chromatography technology	Bisson N (2011)	1
LAT	0	LCP2	0	affinity chromatography technology	Xie JJ (2013)	1
GAB2	3	ZAP70	5	affinity chromatography technology	Yamasaki S (2001)	1
CUL3	17	NYAP1	4	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	KHDRBS1	1	affinity chromatography technology	Ertych N (2016)	1
FASLG	0	PRMT2	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGFR	5	SOCS1	1	affinity chromatography technology	Xia L (2002)	1
PXN	1	BCR	3	affinity chromatography technology	Salgia R (1995)	1
GRB2	2	GAB1	3	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, far western blotting, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Oneyama C (2002), Lewitzky M (2001), Lewitzky M (2001), Lewitzky M (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Bandyopadhyay S (2010), Ingham RJ (1998), Brehme M (2009), Fixman ED (1997), Bisson N (2011), Huttlin EL (2017), Kapoor GS (2010), Lehr S (1999)	15
CBLB	3	CRKL	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Elly C (1999), Elly C (1999), Grossmann A (2015)	3
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
STAT3	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Gunaje JJ (2001), M L (2016)	2
CBL	7	ACTA1	1	affinity chromatography technology	Valiya Veettil M (2011)	1
BRCA1	7	AKT1	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down	Altiok S (1999), Xiang T (2008), Xiang T (2008), Xiang T (2008), Xiang T (2011)	5
GRB2	2	PIK3CA	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Bisson N (2011), Huttlin EL (2017)	3
BCR	3	GAB2	3	affinity chromatography technology	Million RP (2004)	1
GRB2	2	SOS1	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Liu SK (1998), Oneyama C (2002), Puil L (1994), Robinson A (1996), Li N (1993), Wong A (2002), Wong A (2002), Reif K (1994), DAngelo G (1999), Nel AE (1995), Pandey P (1995), Buday L (1994), Tong XK (2000), Park RK (1999), Okada S (1996), Okada S (1996), Okada S (1996), Germani A (1999), Park RK (1999), Chin H (1997), Saci A (2002), Sastry L (1997), Spivak-Kroizman T (1994), Ingham RJ (1996), Wang Y (1999), Chu J (1998), Brehme M (2009), Houtman JC (2006), Lao DH (2006), Bisson N (2011), Wang J (2011), Ng MY (2017), Huttlin EL (2017), Kapoor GS (2010), Saito T (2004), Klint P (1995)	37
EGFR	5	NTRK2	10	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SYK	3	HDAC3	5	affinity chromatography technology, pull down	Wang L (2005), Wang L (2005)	2
AKT1	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Kim AH (2001), Kim AH (2001)	2
HAVCR2	0	PIK3CB	2	affinity chromatography technology	Huttlin EL (2017)	1
CD3E	0	PIK3R2	3	affinity chromatography technology	Alcazar I (2009)	1
KIT	4	GRB10	4	two hybrid, pull down, affinity chromatography technology	Jahn T (2002), Jahn T (2002), Jahn T (2002)	3
RASD2	1	AKT1	1	affinity chromatography technology	Bang S (2012)	1
HTT	14	GRB2	2	affinity chromatography technology, pull down	Liu YF (1997), Liu YF (1997)	2
ZAP70	5	FYN	1	genetic interference, affinity chromatography technology	Neumeister EN (1995), Neumeister EN (1995)	2
EGFR	5	ERBB3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marques MM (1999), Li J (2013), Li J (2013), Sharif A (2009)	4
GRB2	2	NCL	1	two hybrid	Bandyopadhyay S (2010)	1
HAVCR2	0	LCK	0	affinity chromatography technology	Rangachari M (2012)	1
MAPT	1	SIRT1	3	pull down, affinity chromatography technology	Min SW (2010), Min SW (2010)	2
NTRK2	10	PIK3R1	6	two hybrid	Suzuki S (2002)	1
CD28	0	DOK1	2	affinity chromatography technology	Klasen S (1998)	1
SYNM	3	PIK3R1	6	affinity chromatography technology	Anggono V (2007)	1
SOCS1	1	PTPN11	20	affinity chromatography technology	Ali S (2003)	1
FGFR2	6	SRC	2	affinity chromatography technology	Schueller AC (2008)	1
SYN1	1	PIK3R1	6	affinity chromatography technology	Onofri F (2000)	1
ARHGAP17	1	PIK3R1	6	pull down	Richnau N (2001)	1
NCK1	0	PIK3R3	0	two hybrid	Grossmann A (2015)	1
DOK1	2	KIT	4	affinity chromatography technology, pull down	Liang X (2002), Liang X (2002)	2
FYN	1	CTNNB1	30	enzymatic study, imaging technique	Piedra J (2003), Chen TC (2014)	2
CD3E	0	NCL	1	pull down	Gil D (2001)	1
TNS4	5	CBL	7	affinity chromatography technology, pull down	Hong SY (2013), Hong SY (2013)	2
LAT	0	CD3E	0	affinity chromatography technology	Munoz P (2003)	1
FASLG	0	PIK3CA	8	unspecified method	Voss M (2009)	1
HAVCR2	0	NISCH	11	affinity chromatography technology	Huttlin EL (2017)	1
LCK	0	5175	0	enzymatic study	Cao MY (1998)	1
IGF1R	5	IRS1	7	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Tartare-Deckert S (1995), Dey BR (1996), Dey BR (1996), Manes S (1999)	4
CBL	7	PIK3R3	0	two hybrid, two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015), Grossmann A (2015)	3
PDGFRA	3	PDGFRB	8	affinity chromatography technology, pull down, affinity chromatography technology	Rupp E (1994), Seifert RA (1989), Huttlin EL (2017)	3
SHC1	0	ESR1	0	affinity chromatography technology, pull down	Song RX (2002), Song RX (2002)	2
PIK3R2	3	CRK	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Brehme M (2009), Brehme M (2009), Grossmann A (2015)	3
SOCS1	1	IGF1R	5	two hybrid	Dey BR (1998)	1
ABL1	9	ERBB3	3	unspecified method	Jones RB (2006)	1
BRCA1	7	FLT3	5	genetic interference	Shen JP (2017)	1
FYN	1	NTRK2	10	pull down, affinity chromatography technology	Iwasaki Y (1998), Iwasaki Y (1998)	2
KIT	4	PIK3CA	8	affinity chromatography technology	Furitsu T (1993)	1
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
FLRT1	4	FGFR1	2	affinity chromatography technology, imaging technique	Wheldon LM (2010), Wheldon LM (2010)	2
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
PRMT2	3	PIK3R2	3	affinity chromatography technology	Huttlin EL (2017)	1
FYN	1	WAS	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, enzymatic study	Banin S (1996), Banin S (1996), Banin S (1996), Banin S (1999), Rivero-Lezcano OM (1995), Suetsugu S (2002)	6
CRK	0	ZAP70	5	pull down	Gelkop S (1999)	1
NTRK1	1	CBLB	3	affinity chromatography technology, affinity chromatography technology	Emdal KB (2015), Emdal KB (2015)	2
CBLB	3	SYK	3	affinity chromatography technology, enzymatic study	Elly C (1999), Wirnsberger G (2016)	2
KIT	4	CRKL	1	pull down, affinity chromatography technology	van Dijk TB (2000), Sattler M (1997)	2
PIK3R1	6	ZAP70	5	affinity chromatography technology	Moon KD (2005)	1
ALOX5	1	ITSN1	5	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	JAK2	1	affinity chromatography technology	Gao B (2001)	1
BCAR1	6	ARHGAP32	11	pull down, affinity chromatography technology, affinity chromatography technology	Zhao C (2003), Zhao C (2003), Nakamura T (2002)	3
NCK1	0	KHDRBS1	1	pull down, far western blotting, affinity chromatography technology, unspecified method, affinity chromatography technology	Tang J (1997), Lawe DC (1997), Lawe DC (1997), Asbach B (2012), Asbach B (2012)	5
PTPN11	20	KIT	4	pull down, affinity chromatography technology, unspecified method	Tauchi T (1994), Kozlowski M (1998), Wollberg P (2003)	3
HAVCR2	0	RIPK4	0	affinity chromatography technology	Huttlin EL (2017)	1
ERBB3	3	PIK3CA	8	affinity chromatography technology, affinity chromatography technology	Li J (2013), Hellyer NJ (2001)	2
NPM1	0	SIRT1	3	affinity chromatography technology	Park G (2010)	1