PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
AURKA	1	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
CDK2	0	HSPA8	4	affinity chromatography technology	Neganova I (2011)	1
CDC20	1	TFDP1	3	affinity chromatography technology	Nath S (2014)	1
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
CDT1	2	HDAC11	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Glozak MA (2009), Glozak MA (2009), Wong PG (2010), Wong PG (2010)	4
CDT1	2	GMNN	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2008), Ballabeni A (2004), Nishitani H (2004), Nishitani H (2004), Teer JK (2008), Roukos V (2007), Wong PG (2010), Sugimoto N (2004), Takeda DY (2005), Ramachandran N (2004), Higa LA (2003), Higa LA (2003), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	15
POTEB3	0	FAM83D	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK1	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDKN2A	1	HSPA8	4	pull down	Souza-Rodrigues E (2007)	1
GMNN	0	MID1	1	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	MSL1	0	affinity chromatography technology	Huttlin EL (2017)	1
CCNA2	1	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
GMNN	0	CDH1	4	affinity chromatography technology	Tsunematsu T (2013)	1
GMNN	0	HERC4	0	affinity chromatography technology	Hein MY (2015)	1
GMNN	0	MCIDAS	2	affinity chromatography technology	Huttlin EL (2017)	1
ARNT	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1A	1	CKS2	0	affinity chromatography technology	Fogeron ML (2013)	1
BAG4	2	HSPA8	4	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Miki K (2002), Miki K (2002), Taipale M (2014), Taipale M (2014)	4
GMNN	0	CDKN1A	1	pull down	Ramachandran N (2004)	1
HDAC3	5	GMNN	0	affinity chromatography technology	Kim MY (2006)	1
FZR1	1	GMNN	0	affinity chromatography technology, enzymatic study, pull down	Pfleger CM (2001), Williamson A (2011), Williamson A (2011)	3
GMNN	0	HECTD1	16	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
CSNK2A1	15	GMNN	0	enzymatic study	Roukos V (2007)	1
GMNN	0	IMPDH1	2	two hybrid	Wang J (2011)	1
CDK3	0	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
CDT1	2	CDK1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Huttlin EL (2017)	4
CDT1	2	CCNA2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teer JK (2008), Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
CDK3	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
GMNN	0	BAG4	2	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	NPHP3	2	affinity chromatography technology	Huttlin EL (2017)	1
AURKA	1	GMNN	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Tsunematsu T (2013), Tsunematsu T (2013), Tsunematsu T (2013)	3
FZR1	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	TFDP1	3	affinity chromatography technology	Hein MY (2015)	1
CDK1	0	CDK3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK2	0	CASP3	0	affinity chromatography technology	Neganova I (2011)	1
FZR1	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	SMARCA4	19	two hybrid, affinity chromatography technology	Becker TM (2009), Becker TM (2009)	2
CKS1B	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	MCM6	5	affinity chromatography technology	Neganova I (2011)	1
CDK3	0	CKS2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GMNN	0	ATM	9	affinity chromatography technology	Hein MY (2015)	1
CDK3	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TGIF2LY	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
CDT1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Li X (2003), Li X (2003), Sugimoto N (2008), Liu E (2004), Liu E (2004), Sugimoto N (2004), Takeda DY (2005), Hein MY (2015)	9
CDK1	0	CDC20	1	enzymatic study, affinity chromatography technology, enzymatic study	Yudkovsky Y (2000), Huttlin EL (2017), Jia L (2016)	3
HMMR	1	FAM83D	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK1	0	TFDP1	3	enzymatic study	Dynlacht BD (1997)	1
SKP2	2	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Bashir T (2010), Rosner M (2009), Rosner M (2004), Zhang H (1995), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
CCNA2	1	CDC20	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Di Fiore B (2010), Di Fiore B (2010), Di Fiore B (2010), Wolthuis R (2008), Wolthuis R (2008), Ge S (2009), Townsend K (2009), Di Fiore B (2010), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Huttlin EL (2017), Izawa D (2012), Hein JB (2016)	25
CASP3	0	GMNN	0	enzymatic study	Roukos V (2007)	1
CSNK2A1	15	SUPT6H	7	enzymatic study	Zhang M (2011)	1
GMNN	0	E2F5	0	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
CDC20	1	GMNN	0	affinity chromatography technology, affinity chromatography technology	Pfleger CM (2001), Tsunematsu T (2013)	2
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CDH1	4	HSPA8	4	affinity chromatography technology, bioid	Catimel B (2005), Guo Z (2014)	2
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
FZR1	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2017)	2
HSPA8	4	HSPBP1	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Stelzl U (2005), Alberti S (2004), Taipale M (2014), Taipale M (2014), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	8
GMNN	0	SUPT6H	7	affinity chromatography technology	Hein MY (2015)	1
KAT7	3	CDT1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Miotto B (2008), Miotto B (2008), Miotto B (2008), Wong PG (2010), Wong PG (2010)	5
KAT7	3	GMNN	0	enzymatic study	Iizuka M (2006)	1
GMNN	0	FAM83D	1	affinity chromatography technology	Huttlin EL (2017)	1
CCNA2	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Amador V (2007), Horton LE (1997), Lin ML (2011), Lin ML (2011), OConnor PM (1993), Varjosalo M (2013), Kikuchi R (2014), Mateo F (2009), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	13
HDAC11	0	GMNN	0	affinity chromatography technology	Wong PG (2010)	1
GMNN	0	CASP8	1	affinity chromatography technology	Hein MY (2015)	1
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
FZR1	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS2	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK3	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
GMNN	0	E2F4	0	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	CEP192	5	affinity chromatography technology	Huttlin EL (2017)	1
HDAC3	5	HSPA8	4	pull down	Guenther MG (2002)	1
RUNDC3A	2	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
AURKA	1	CSNK2A1	15	affinity chromatography technology	Fogeron ML (2013)	1
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
CASP3	0	CDH1	4	imaging technique	Chen TC (2014)	1
GMNN	0	CTC1	5	affinity chromatography technology	Huttlin EL (2017)	1
CDK1	0	CKS2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Varjosalo M (2013), Radulovic M (2010), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
CDK2	0	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDK3	0	CDT1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GMNN	0	KLHL22	3	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	HSPBP1	0	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	ZMYM4	4	biochemical	Wan C (2015)	1
CKS1B	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CSNK2A1	15	HDAC3	5	enzymatic study, affinity chromatography technology	Zhang X (2005), Rajendran P (2011)	2
HDAC3	5	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Qiu Z (2008), Zhu P (2006)	2
CCNA2	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Amador V (2007), Wu G (1997), Lin ML (2011), Chen J (1996), Levkau B (1998), Poon RY (1996), Fogeron ML (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
GMNN	0	ZNF439	1	two hybrid	Rolland T (2014)	1
GMNN	0	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
CDK2	0	TFDP1	3	enzymatic study, affinity chromatography technology, affinity chromatography technology	Dynlacht BD (1997), Dynlacht BD (1997), So J (2015)	3
CDC20	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
IMPDH1	2	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	CDH1	4	affinity chromatography technology, enzymatic study	Chen JY (2011), Liu YQ (2015)	2
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
CDT1	2	CDC20	1	pull down	Sugimoto N (2008)	1
EWSR1	2	GMNN	0	bioid	Elzi DJ (2014)	1
ARNT	1	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
E2F5	0	TFDP1	3	biochemical, two hybrid, affinity chromatography technology	Hijmans EM (1995), Sardet C (1995), Hauri S (2016)	3
GMNN	0	TFDP1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Hauri S (2016)	2
CSNK2A1	15	CDK1	0	enzymatic study	Russo GL (1992)	1
CKS2	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
CDT1	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu E (2004), Sugimoto N (2004), Sugimoto N (2004), Takeda DY (2005), Varjosalo M (2013), Hein MY (2015)	6
NCF1	2	GMNN	0	two hybrid	Takeshita F (2005)	1
GMNN	0	ZZEF1	5	affinity chromatography technology	Huttlin EL (2017)	1
HDAC3	5	E2F4	0	affinity chromatography technology, affinity chromatography technology	Li Y (2012), Li Y (2012)	2
STN1	0	CTC1	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GMNN	0	STN1	0	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	CERK	4	affinity chromatography technology	Huttlin EL (2017)	1
MID1	1	MID2	1	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reymond A (2001), Reymond A (2001), Short KM (2002), Short KM (2002), Short KM (2002), Short KM (2002), Short KM (2006), Short KM (2006), Rolland T (2014), Gholkar AA (2016), Gholkar AA (2016), Gholkar AA (2016), Gholkar AA (2016)	13
GMNN	0	EHMT1	18	affinity chromatography technology	Hein MY (2015)	1
REPIN1	3	GMNN	0	affinity chromatography technology, affinity chromatography technology, pull down	Kim MY (2006), Kim MY (2006), Kim MY (2006)	3
GMNN	0	MTMR1	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
CCNA2	1	CKS2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Huttlin EL (2017)	4
GMNN	0	HMMR	1	affinity chromatography technology	Huttlin EL (2017)	1
CDC20	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Amador V (2007), Fogeron ML (2013)	2
CDKN1A	1	SUPT6H	7	affinity chromatography technology	Fogeron ML (2013)	1
CASP8	1	CASP3	0	enzymatic study, enzymatic study, enzymatic study	Guo Y (2002), Srinivasula SM (1996), Chandra D (2004)	3
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
CDKN1A	1	HDAC11	0	two hybrid	Stelzl U (2005)	1
ZNF785	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
CASP3	0	ARNT	1	enzymatic study, pull down	Suzuki H (2001), Suzuki H (2001)	2
CDK3	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
POTEB3	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	MID2	1	affinity chromatography technology	Huttlin EL (2017)	1
CKS1B	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jackman M (2002), Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
SMARCA4	19	SMARCA2	17	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Reyes JC (1997), Pal S (2003), Ito T (2008), Ito T (2008), Havugimana PC (2012)	5
AURKA	1	HMMR	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Maxwell CA (2011), Maxwell CA (2011), Maxwell CA (2011)	3
PNKD	2	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GMNN	0	CDKN2A	1	pull down, two hybrid	Ramachandran N (2004), Daakour S (2016)	2
TFDP1	3	CDK3	0	affinity chromatography technology	Hofmann F (1996)	1
CDC20	1	AURKA	1	affinity chromatography technology, affinity chromatography technology	Farruggio DC (1999), Katayama H (2012)	2
SKP2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Calvisi DF (2009), Cen B (2010), Bashir T (2004), Bashir T (2004), Hu D (2011), Fukushima H (2013), Gao D (2009), Gao D (2009), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012), Huttlin EL (2017)	12
GMNN	0	MYO5C	8	affinity chromatography technology	Huttlin EL (2017)	1
CCNA2	1	FZR1	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Jin L (2008), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Williamson A (2011), Huttlin EL (2017), Choudhury R (2016)	8
C2orf68	1	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TFDP1	3	MCIDAS	2	affinity chromatography technology	Hauri S (2016)	1
CDC20	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Bashir T (2004), Huttlin EL (2017)	2
SKP2	2	ATM	9	affinity chromatography technology	Wu J (2012)	1
GMNN	0	TYK2	1	affinity chromatography technology	Huttlin EL (2017)	1
TFDP1	3	E2F4	0	two hybrid, pull down, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Sardet C (1995), Dynlacht BD (1997), Beijersbergen RL (1994), Ginsberg D (1994), Trimarchi JM (1998), Hauri S (2016)	6
MID2	1	ZNF785	0	two hybrid	Rolland T (2014)	1
SMARCA2	17	GMNN	0	affinity chromatography technology	Roukos V (2007)	1
CDC20	1	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
POTEB3	0	HMMR	1	affinity chromatography technology	Huttlin EL (2017)	1
GMNN	0	CCDC146	3	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
GMNN	0	TARBP1	3	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	CEP192	5	affinity chromatography technology	Moser SC (2013)	1
CCNA2	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Naderi S (2005), Varshochi R (2005), Di Fiore B (2010), Mateo F (2009), Abbas T (2007), Schulman BA (1998), Datta NS (1998), Wu G (1997), Sebastian B (1993), Liu S (2009), Ciarallo S (2002), Wolthuis R (2008), Vicent GP (2011), Zhang H (1995), Sayle KL (2003), Jeffrey PD (1995), Davies TG (2001), Cook A (2002), Pevarello P (2006), Levkau B (1998), Poon RY (1996), OConnor PM (1993), Davies TG (2002), Kontopidis G (2003), Andrews MJ (2004), Pevarello P (2004), Pevarello P (2005), Varjosalo M (2013), Varjosalo M (2013), Kikuchi R (2014), Kikuchi R (2014), Mateo F (2009), So J (2015), Okamoto K (2002), Song MS (2011), Huttlin EL (2015), Di Fiore B (2015), Pan ZQ (1993), Pan ZQ (1993), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	43
CDT1	2	MCM6	5	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology	Sugimoto N (2008), Teer JK (2008), Liu C (2011), Hein MY (2015)	4
AURKA	1	CDKN2A	1	affinity chromatography technology	Ewing RM (2007)	1
MYO5C	8	CLTB	0	affinity chromatography technology	Hein MY (2015)	1
ATM	9	HSPA8	4	two hybrid	Arroyo R (2015)	1
AURKA	1	CEP192	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Hutchins JR (2010), Fogeron ML (2013), Huttlin EL (2015), Firat-Karalar EN (2014), Huttlin EL (2017)	5
CKS2	0	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
SKP2	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Bashir T (2004), Kelly A (2014), Craney A (2016), Huttlin EL (2017)	5
GMNN	0	CLTB	0	affinity chromatography technology	Hein MY (2015)	1
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
CASP3	0	CDKN1A	1	enzymatic study, enzymatic study, enzymatic study, imaging technique	Levkau B (1998), Park JA (1998), Zhang Y (1999), Chen TC (2014)	4
FZR1	1	CKS1B	0	affinity chromatography technology	Bashir T (2004)	1
HDAC3	5	REPIN1	3	affinity chromatography technology	Kim MY (2006)	1
EWSR1	2	HDAC3	5	two hybrid	Ravasi T (2010)	1
CKS1B	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	E2F4	0	affinity chromatography technology	So J (2015)	1
ARNT	1	GMNN	0	two hybrid	Wang J (2011)	1
CDK2	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
GMNN	0	MCM6	5	pull down	Ramachandran N (2004)	1
SMARCA4	19	GMNN	0	affinity chromatography technology, affinity chromatography technology, pull down	Seo S (2005), Seo S (2005), Seo S (2005)	3
CDKN1A	1	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
CDKN2A	1	MCM6	5	affinity chromatography technology, affinity chromatography technology, pull down	Souza-Rodrigues E (2007), Souza-Rodrigues E (2007), Souza-Rodrigues E (2007)	3