PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
MYC 2 MSH6 2 affinity chromatography technology, affinity chromatography technology Ewing RM (2007), Koch HB (2007) 2
BARD1 4 MSH2 4 pull down Wang Q (2001) 1
SLX4 6 PCNA 0 affinity chromatography technology Ghosal G (2012) 1
MSH3 4 OTUD7B 3 biochemical Havugimana PC (2012) 1
APLF 3 MSH3 4 affinity chromatography technology Huttlin EL (2017) 1
PMS2 4 MSH6 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Cannavo E (2007), Matton N (2000), Matton N (2000), Plotz G (2003) 4
RPA3 2 RPA2 0 biochemical, x-ray crystallography, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology Bochkareva E (1998), Bochkareva E (2002), Havugimana PC (2012), Du Y (2009), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017) 7
HUS1 1 MSH3 4 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
PCNA 0 RAD9A 1 affinity chromatography technology Dahm K (2002) 1
XPA 1 RPA1 0 two hybrid, pull down, affinity chromatography technology Li L (1995), Li L (1995), Lange SS (2009) 3
FOXA1 2 MSH3 4 affinity chromatography technology Li X (2015) 1
BRCA1 7 MYC 2 affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003) 11
HDAC6 0 MSH2 4 affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study New M (2013), Zhang M (2014), Zhang M (2014), Zhang M (2014), Zhang M (2014), Zhang M (2014), Zhang M (2014) 7
HDAC6 0 MSH3 4 affinity chromatography technology Zhang M (2014) 1
SLX4 6 MSH3 4 affinity chromatography technology Svendsen JM (2009) 1
RPA1 0 RPA2 0 affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017) 13
EXO1 3 MLH1 6 pull down, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, pull down Schmutte C (2001), Schmutte C (2001), Dherin C (2009), Dherin C (2009), Cannavo E (2007), Engels K (2011), Engels K (2011), Nielsen FC (2004), Andersen SD (2012), Jaeger AC (2001) 10
RPA4 0 RPA1 0 two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology Keshav KF (1995), Keshav KF (1995), Ghospurkar PL (2014), Huttlin EL (2015), Huttlin EL (2017) 5
MSH2 4 MLH1 6 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique Wang Y (2000), Matton N (2000), Plotz G (2003), Plotz G (2003), Chen TC (2014) 5
RAD9A 1 MSH3 4 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
PMS2 4 PCNA 0 affinity chromatography technology, far western blotting, pull down Cannavo E (2007), Dzantiev L (2004), Genschel J (2017) 3
MCM9 1 MSH2 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique Hutchins JR (2016), Traver S (2015), Traver S (2015), Traver S (2015), Traver S (2015) 5
HDAC6 0 MSH6 2 affinity chromatography technology, affinity chromatography technology Zhang M (2014), Zhang M (2014) 2
XPA 1 RPA4 0 two hybrid, pull down Li L (1995), Li L (1995) 2
MSH2 4 RPA4 0 pull down Zhao J (2009) 1
BARD1 4 MLH1 6 biochemical Greenberg RA (2006) 1
BARD1 4 MSH3 4 pull down Wang Q (2001) 1
NTRK1 1 MSH3 4 affinity chromatography technology Emdal KB (2015) 1
KATNB1 0 MSH3 4 biochemical Havugimana PC (2012) 1
NTRK1 1 MLH1 6 affinity chromatography technology Emdal KB (2015) 1
PCNA 0 EXO1 3 imaging technique, far western blotting Nielsen FC (2004), Dzantiev L (2004) 2
RAD9A 1 MSH6 2 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
RAD1 0 RPA1 0 affinity chromatography technology, affinity chromatography technology Wu X (2005), Wu X (2005) 2
RPA1 0 MSH2 4 affinity chromatography technology, biochemical Marechal A (2014), Wan C (2015) 2
SLC39A9 1 MSH3 4 affinity chromatography technology Huttlin EL (2017) 1
MCM9 1 MSH6 2 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hutchins JR (2016), Traver S (2015), Traver S (2015) 3
MCM9 1 MSH3 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Hutchins JR (2016), Traver S (2015), Traver S (2015) 3
CDC42 3 MSH3 4 affinity chromatography technology Hein MY (2015) 1
MSH2 4 MSH3 4 affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, biochemical, pull down Wang Y (2003), Guerrette S (1998), Bocker T (1999), Bocker T (1999), Acharya S (1996), Palombo F (1996), Havugimana PC (2012), Owen BA (2009) 8
RAD9A 1 RAD1 0 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Dufault VM (2003), Dufault VM (2003), Volkmer E (1999), Volkmer E (1999), Griffith JD (2002), Hirai I (2002), Hirai I (2002), Lindsey-Boltz LA (2001), Huttlin EL (2015), Huttlin EL (2017) 10
RPA4 0 RPA2 0 two hybrid, affinity chromatography technology Keshav KF (1995), Keshav KF (1995) 2
RPA3 2 MSH3 4 affinity chromatography technology Marechal A (2014) 1
MSH2 4 MSH6 2 biochemical, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, biochemical, affinity chromatography technology, imaging technique Wang Y (2000), Wang Y (2003), Guerrette S (1998), Bocker T (1999), Bocker T (1999), Acharya S (1996), Matton N (2000), Matton N (2000), Yang Q (2004), Havugimana PC (2012), Gradia S (1997), Owen BA (2009), Wan C (2015), Hein MY (2015), Chen TC (2014) 15
BRCA1 7 PCNA 0 affinity chromatography technology, affinity chromatography technology Hill SJ (2014), Ertych N (2016) 2
NTRK1 1 SMARCAD1 1 affinity chromatography technology Emdal KB (2015) 1
HDAC6 0 PCNA 0 affinity chromatography technology New M (2013) 1
RPA4 0 RPA3 2 two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Keshav KF (1995), Keshav KF (1995), Huttlin EL (2015), Huttlin EL (2017) 4
MLH1 6 PCNA 0 far western blotting, pull down Dzantiev L (2004), Genschel J (2017) 2
HUS1 1 RPA3 2 genetic interference Horlbeck MA (2018) 1
HUS1 1 RPA1 0 affinity chromatography technology, affinity chromatography technology Wu X (2005), Wu X (2005) 2
TSC22D2 2 MSH3 4 two hybrid Li Q (2016) 1
MLH1 6 MSH3 4 affinity chromatography technology, two hybrid Cannavo E (2007), Rolland T (2014) 2
EXO1 3 MSH3 4 pull down Schmutte C (2001) 1
MSH3 4 XPA 1 pull down Zhao J (2009) 1
NTRK1 1 RPA1 0 affinity chromatography technology Emdal KB (2015) 1
KARS 1 MSH3 4 biochemical Wan C (2015) 1
EXO1 3 PMS2 4 affinity chromatography technology, affinity chromatography technology Schmutte C (2001), Cannavo E (2007) 2
SMARCAD1 1 MSH2 4 affinity chromatography technology Rowbotham SP (2011) 1
SLX4 6 MSH2 4 affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology Svendsen JM (2009), Svendsen JM (2009), Svendsen JM (2009), Ghosal G (2012) 4
BRCA1 7 RPA1 0 affinity chromatography technology, imaging technique, affinity chromatography technology Suhasini AN (2011), Mok MT (2010), Tian F (2013) 3
MLH1 6 PMS2 4 two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, pull down, pull down, pull down, affinity chromatography technology Mac Partlin M (2003), Mac Partlin M (2003), Kondo E (2001), Kondo E (2001), Kondo E (2001), Kondo E (2001), Guerrette S (1999), Dherin C (2009), Cannavo E (2007), Cannavo E (2007), Cannavo E (2007), Cannavo E (2007), Xie J (2010), Peng M (2007), Nielsen FC (2004), Matton N (2000), Plotz G (2003), Havugimana PC (2012), Brieger A (2010), Dzantiev L (2004), Jaeger AC (2001), Sacho EJ (2008), Hein MY (2015) 23
BRCA1 7 MSH2 4 two hybrid, pull down, biochemical, affinity chromatography technology, genetic interference Wang Q (2001), Wang Q (2001), Wang Y (2000), Wada-Hiraike O (2005), Peng M (2014) 5
KARS 1 SNX8 1 biochemical Wan C (2015) 1
BRCA1 7 PMS2 4 affinity chromatography technology Hill SJ (2014) 1
MCM9 1 MLH1 6 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique Hutchins JR (2016), Traver S (2015), Traver S (2015), Traver S (2015), Traver S (2015) 5
MSH3 4 RPA1 0 biochemical, affinity chromatography technology Havugimana PC (2012), Marechal A (2014) 2
UHRF2 1 PCNA 0 far western blotting, x-ray crystallography, unspecified method, affinity chromatography technology Mori T (2011), Chen W (2017), Chen W (2017), Lai M (2016) 4
RPA2 0 MSH3 4 affinity chromatography technology Marechal A (2014) 1
MYC 2 NTRK1 1 genetic interference Toyoshima M (2012) 1
PMS2 4 MSH2 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Cannavo E (2007), Matton N (2000), Plotz G (2003) 3
RAD9A 1 MSH2 4 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
PCNA 0 RPA1 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Ohta S (2002), Ogi T (2010), Takasaki Y (2001), Gong Z (2011), Miccoli L (2005), Han J (2014) 6
NTRK1 1 KARS 1 affinity chromatography technology Emdal KB (2015) 1
RPA2 0 MSH2 4 affinity chromatography technology Marechal A (2014) 1
MSH3 4 MSH6 2 biochemical Havugimana PC (2012) 1
PCNA 0 RPA3 2 affinity chromatography technology Takasaki Y (2001) 1
PMS2 4 MSH3 4 affinity chromatography technology Cannavo E (2007) 1
BRCA1 7 MLH1 6 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wang Y (2000), Cannavo E (2007), Suhasini AN (2011), Hill SJ (2014) 4
MYC 2 MLH1 6 two hybrid, two hybrid, pull down, affinity chromatography technology Mac Partlin M (2003), Mac Partlin M (2003), Mac Partlin M (2003), Mac Partlin M (2003) 4
BRCA1 7 RCHY1 0 affinity chromatography technology Ertych N (2016) 1
BRCA1 7 MSH3 4 unspecified method, pull down Rodriguez M (2003), Wang Q (2001) 2
RAD1 0 RPA2 0 affinity chromatography technology Wu X (2005) 1
HUS1 1 PCNA 0 two hybrid, two hybrid, affinity chromatography technology Komatsu K (2000), Komatsu K (2000), Komatsu K (2000) 3
NTRK1 1 MSH6 2 affinity chromatography technology Emdal KB (2015) 1
MSH3 4 ORAOV1 0 biochemical Havugimana PC (2012) 1
XPA 1 RPA2 0 pull down, affinity chromatography technology Mer G (2000), Fan W (2010) 2
RAD1 0 MSH6 2 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
MSH6 2 MLH1 6 biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Wang Y (2000), Matton N (2000), Matton N (2000), Plotz G (2003), Plotz G (2003) 5
SMARCAD1 1 MSH3 4 affinity chromatography technology Rowbotham SP (2011) 1
MSH6 2 PCNA 0 far western blotting, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, far western blotting, affinity chromatography technology, biochemical, affinity chromatography technology Kleczkowska HE (2001), Kleczkowska HE (2001), Clark AB (2000), Ohta S (2002), Jascur T (2011), Schoepf B (2012), Havugimana PC (2012), Dzantiev L (2004), Han J (2014), Wan C (2015), Hein MY (2015) 11
MSH3 4 RCHY1 0 two hybrid Wang J (2011) 1
IKBKG 0 MSH3 4 affinity chromatography technology Hein MY (2015) 1
RAD9A 1 RPA1 0 affinity chromatography technology Wu X (2005) 1
MSH3 4 PCNA 0 far western blotting, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, two hybrid Kleczkowska HE (2001), Kleczkowska HE (2001), Clark AB (2000), Ohta S (2002), Ohta S (2002), Rolland T (2014) 6
IKBKG 0 MYC 2 affinity chromatography technology Kim BY (2010) 1
HUS1 1 MSH2 4 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
RAD9A 1 RPA2 0 affinity chromatography technology Wu X (2005) 1
BRCA1 7 MSH6 2 two hybrid, pull down, biochemical, affinity chromatography technology Wang Q (2001), Wang Q (2001), Wang Y (2000), Hill SJ (2014) 4
NTRK1 1 HDAC6 0 affinity chromatography technology Emdal KB (2015) 1
PCNA 0 RPA2 0 affinity chromatography technology Takasaki Y (2001) 1
MYC 2 MSH2 4 affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe Mac Partlin M (2003), Koch HB (2007), Ivanov AA (2017) 3
RPA3 2 RPA1 0 biochemical, x-ray crystallography, affinity chromatography technology, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology Bochkareva E (1998), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Du Y (2009), Wan C (2015), Hein MY (2015), Elia AE (2015) 8
HDAC6 0 MLH1 6 affinity chromatography technology, affinity chromatography technology Zhang M (2014), Zhang M (2014) 2
NTRK1 1 MSH2 4 affinity chromatography technology Emdal KB (2015) 1
HUS1 1 MSH6 2 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
RAD1 0 MSH3 4 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
PCNA 0 MSH2 4 affinity chromatography technology, far western blotting Ohta S (2002), Dzantiev L (2004) 2
HUS1 1 RAD1 0 affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Volkmer E (1999), Volkmer E (1999), Hang H (2002), Hirai I (2004), Warmerdam DO (2010), Huttlin EL (2015), Huttlin EL (2017) 7
SLX4 6 MSH6 2 affinity chromatography technology Ghosal G (2012) 1
RPA3 2 MSH2 4 affinity chromatography technology Marechal A (2014) 1
SMARCAD1 1 MSH6 2 affinity chromatography technology Rowbotham SP (2011) 1
RAD1 0 MSH2 4 affinity chromatography technology, far western blotting Bai H (2010), Bai H (2010) 2
HUS1 1 RPA2 0 affinity chromatography technology Wu X (2005) 1
MSH3 4 RPA4 0 pull down Zhao J (2009) 1
FOXA1 2 RPA2 0 affinity chromatography technology Li X (2015) 1
SMARCAD1 1 PCNA 0 pull down, fluorescent resonance energy transfe Rowbotham SP (2011), Rowbotham SP (2011) 2
BRCA1 7 KARS 1 affinity chromatography technology Ertych N (2016) 1
SNX8 1 MSH3 4 biochemical Wan C (2015) 1
RAD9A 1 HUS1 1 pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Dufault VM (2003), Dufault VM (2003), Volkmer E (1999), Volkmer E (1999), Griffith JD (2002), Hirai I (2002), Huttlin EL (2015), Huttlin EL (2017) 8
MYC 2 MSH3 4 affinity chromatography technology Koch HB (2007) 1
NTRK1 1 PCNA 0 affinity chromatography technology Emdal KB (2015) 1
BARD1 4 MSH6 2 pull down, biochemical Wang Q (2001), Greenberg RA (2006) 2
MSH2 4 XPA 1 pull down Zhao J (2009) 1
BRCA1 7 BARD1 4 two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016) 91
UHRF2 1 MSH3 4 affinity chromatography technology Lai M (2016) 1
ZSCAN26 1 MSH3 4 affinity chromatography technology Hein MY (2015) 1
MSH2 4 EXO1 3 two hybrid, pull down, pull down, pull down, pull down Rasmussen LJ (2000), Schmutte C (1998), Schmutte C (2001), Dherin C (2009), Andersen SD (2012) 5
SLX4 6 RPA1 0 affinity chromatography technology Ouyang J (2015) 1
LMO2 2 MSH3 4 affinity chromatography technology Huttlin EL (2017) 1
UHRF2 1 RPA1 0 affinity chromatography technology Lai M (2016) 1