Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
KIT 3815 SU-14813 CHEMBL3545160 inhibitor GuideToPharmacologyInteractions, ChemblInteractions
KIT 3815 SU-014813 CHEMBL1721885 inhibitor ChemblInteractions
KIT 3815 AST-487 CHEMBL574738 inhibitor GuideToPharmacologyInteractions
KIT 3815 DIPHENIDOL CHEMBL936 inhibitor CKB, GuideToPharmacologyInteractions
KIT 3815 JNJ-40346527 CHEMBL3545319 inhibitor GuideToPharmacologyInteractions
KIT 3815 SU-11652 CHEMBL13485 inhibitor GuideToPharmacologyInteractions
KIT 3815 PAZOPANIB HYDROCHLORIDE CHEMBL1201733 inhibitor ChemblInteractions, TTD
KIT 3815 CM-082 CHEMBL3545427 inhibitor ChemblInteractions
KIT 3815 Anlotinib CHEMBL3545021 inhibitor ChemblInteractions
KIT 3815 CHEMBL2325503 CHEMBL2325503 CKB 28611108
KIT 3815 FORETINIB CHEMBL1230609 inhibitor ChemblInteractions
KIT 3815 XL-999 CHEMBL3545285 inhibitor TdgClinicalTrial, ChemblInteractions
KIT 3815 DASATINIB CHEMBL1421 antagonist, inhibitor ChemblInteractions, CKB, DrugBank, OncoKB, CancerCommons, TEND, TALC, MyCancerGenomeClinicalTrial, TdgClinicalTrial, CGI, CIViC, DoCM 23582185, 25594040, 17699867, 21689725, 18024392, 18986703, 19671763, 16397263, 16434489, 17351742, 17419150, 22357255, 19467857, 23140824, 22270258, 21456006, 17372901, 21953054, 24045550, 25157968, 22504184, 19164557, 23714533, 15972446, 16912224, 17259998, 16384925, 16731599, 18559612, 21642685, 22932406, 23149070, 15685537
KIT 3815 SUNITINIB CHEMBL535 inhibitor GuideToPharmacologyInteractions, TALC, MyCancerGenomeClinicalTrial, DrugBank, OncoKB, TEND, TdgClinicalTrial, TTD, MyCancerGenome, CGI, CIViC, CKB, DoCM 12748309, 11752352, 14753710, 12873999, 17367763, 17545799, 17046465, 19282169, 25641662, 25592632, 20571495, 18235121, 12181401, 16098458, 15451219, 23177515, 19461405, 18421059, 21642685, 21690468, 22261812, 16638875, 22439647, 18955458, 19861435, 25239608, 23582185, 25594040, 26772734, 19164557, 22357254, 23375402, 21969494
KIT 3815 CHEMBL286939 CHEMBL286939 DrugBank 17139284, 17016423
KIT 3815 AMUVATINIB CHEMBL2103851 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, DrugBank, TTD 17325667
KIT 3815 AKN-028 CHEMBL3545281 inhibitor GuideToPharmacologyInteractions
KIT 3815 CRENOLANIB CHEMBL2105728 inhibitor GuideToPharmacologyInteractions
KIT 3815 LUCITANIB CHEMBL2220486 inhibitor GuideToPharmacologyInteractions
KIT 3815 MIDOSTAURIN CHEMBL608533 inhibitor MyCancerGenome, CKB, ChemblInteractions, CIViC, MyCancerGenomeClinicalTrial, FDA 27355533, 25209843
KIT 3815 ENMD-2076 CHEMBL482968 inhibitor TdgClinicalTrial, ChemblInteractions
KIT 3815 SORAFENIB TOSYLATE CHEMBL1200485 inhibitor ChemblInteractions
KIT 3815 SUNITINIB MALATE CHEMBL1567 inhibitor ChemblInteractions, TTD
KIT 3815 CABOZANTINIB CHEMBL2105717 inhibitor MyCancerGenome, CKB 25836719, 27777285, 24205792
KIT 3815 MOTESANIB DIPHOSPHATE CHEMBL2107357 inhibitor TTD
KIT 3815 INFIGRATINIB CHEMBL1852688 CKB 25673643
KIT 3815 TANDUTINIB CHEMBL124660 inhibitor MyCancerGenome, GuideToPharmacologyInteractions, ChemblInteractions
KIT 3815 MASITINIB CHEMBL1908391 inhibitor MyCancerGenome, TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, CancerCommons, MyCancerGenomeClinicalTrial
KIT 3815 DOVITINIB CHEMBL522892 inhibitor ClearityFoundationClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
KIT 3815 XL-820 CHEMBL3545402 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, DrugBank
KIT 3815 SORAFENIB CHEMBL1336 antagonist, inhibitor TdgClinicalTrial, DrugBank, GuideToPharmacologyInteractions, OncoKB, TALC, MyCancerGenome, TEND, CGI, CIViC, CKB, DoCM 17229632, 17545544, 17178882, 17102120, 17272980, 23140824, 22270258, 22357255, 19467857, 21456006, 19461405, 25592632, 20571495, 17419150, 18936790, 20372153, 19671763, 17699867, 24317392, 25363205, 19139124, 20970876, 22665524, 22357254
KIT 3815 TELATINIB CHEMBL2079588 inhibitor TALC, MyCancerGenome, ChemblInteractions
KIT 3815 OSI-930 CHEMBL1614710 inhibitor GuideToPharmacologyInteractions, ChemblInteractions, DrugBank, TTD
KIT 3815 LINIFANIB CHEMBL223360 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, DrugBank
KIT 3815 CEDIRANIB CHEMBL491473 inhibitor TALC, GuideToPharmacologyInteractions, ChemblInteractions
KIT 3815 CHEMBL406375 CHEMBL406375 inhibitor GuideToPharmacologyInteractions
KIT 3815 CHEMBL1908396 CHEMBL1908396 inhibitor GuideToPharmacologyInteractions
KIT 3815 QUIZARTINIB CHEMBL576982 inhibitor CKB, GuideToPharmacologyInteractions, ChemblInteractions, DoCM 24045550, 25157968, 22504184, 19164557, 21689725, 18986703, 23714533, 15972446, 23582185, 16912224, 18024392, 17259998, 16384925, 16731599, 23497317
KIT 3815 VATALANIB CHEMBL101253 inhibitor TALC, TdgClinicalTrial, ChemblInteractions
KIT 3815 PEMBROLIZUMAB CHEMBL3137343 CKB 28514312
KIT 3815 CYTARABINE CHEMBL803 CKB 18986703
KIT 3815 SEMAXANIB CHEMBL276711 inhibitor GuideToPharmacologyInteractions, ChemblInteractions
KIT 3815 NILOTINIB CHEMBL255863 antagonist, inhibitor TTD, DrugBank, OncoKB, MyCancerGenomeClinicalTrial, CancerCommons, CGI, CIViC, CKB 17699867, 22357255, 19467857, 23140824, 22270258, 21456006, 17419150, 22068222, 25695690, 22119758, 19671763, 17372901, 28720666, 28843487, 28327988, 23582185, 25594040, 25209843, 20442311
KIT 3815 PAZOPANIB CHEMBL477772 inhibitor TALC, MyCancerGenome, GuideToPharmacologyInteractions, DrugBank, MyCancerGenomeClinicalTrial, TTD 17288876
KIT 3815 REGORAFENIB CHEMBL1946170 inhibitor DrugBank, CGI, OncoKB, ChemblInteractions, TALC, MyCancerGenomeClinicalTrial, MyCancerGenome, CKB 18235121, 12181401, 17046465, 19282169, 25641662, 16098458, 15451219, 23177515, 25239608, 27371698, 21170960
KIT 3815 PONATINIB CHEMBL1171837 inhibitor CKB, CGI, DrugBank 23539538, 2015, 10517, 25239608, 10535, 21482694, 24552773, 22301675
KIT 3815 PHENOBARBITAL CHEMBL40 inhibitor GuideToPharmacologyInteractions
KIT 3815 Famitinib CHEMBL3545026 inhibitor GuideToPharmacologyInteractions, ChemblInteractions
KIT 3815 IMATINIB CHEMBL941 inhibitor OncoKB, TALC, TTD, CIViC, FDA, MyCancerGenome, TdgClinicalTrial, TEND, CGI, CKB, DoCM 18235121, 12181401, 17046465, 19282169, 25641662, 16098458, 15451219, 23177515, 23775962, 21642685, 14645423, 18421059, 19671763, 17372901, 16954519, 15201427, 21690468, 16624552, 16143141, 22114577, 17699867, 21953054, 22261812, 18955458, 18955451, 23582185, 21689725, 17259998, 25673643, 19861435, 25003536, 25239608, 27777285, 27370604, 25594040, 24317392, 16015387, 20372153, 28611108, 26687836, 28196207, 24419427, 15236194, 23567324, 26316776, 21969494, 19812602, 12481435, 15790786, 18751412, 16751810, 25015329, 18795925, 16462496, 12374669, 27980106, 28334365, 22357254, 23375402, 25157968, 19175693, 7530509, 18980976, 16046538, 18936790, 11276010, 16731599, 16908931, 9438854, 15930355, 15685537, 16638875, 22355224, 17363509, 22932406, 24687822, 24045550, 22504184, 19164557, 18986703, 23714533, 15972446, 16912224, 18024392, 16384925, 20088873, 21159146
KIT 3815 MOTESANIB CHEMBL572881 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, CKB, ChemblInteractions, TTD 20633291
KIT 3815 IMATINIB MESYLATE CHEMBL1642 inhibitor ChemblInteractions, MyCancerGenomeClinicalTrial
KIT 3815 AXITINIB CHEMBL1289926 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, CancerCommons
KIT 3815 LENVATINIB CHEMBL1289601 TdgClinicalTrial
KIT 3815 MK-2206 CHEMBL1079175 CKB 27370604
KIT 3815 BEVACIZUMAB CHEMBL1201583 CKB 25363205
KIT 3815 TRAMETINIB CHEMBL2103875 CKB 28514312
KIT 3815 PLX-3397 CHEMBL3545158 inhibitor MyCancerGenome, CKB, GuideToPharmacologyInteractions, ChemblInteractions, CancerCommons 24583793
KIT 3815 PD-0325901 CHEMBL507361 CKB 26936919

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID