Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
JAK3 3718 CHEMBL21156 CHEMBL21156 inhibitor GuideToPharmacologyInteractions, DrugBank 10592235
JAK3 3718 ACALABRUTINIB CHEMBL3707348 inhibitor GuideToPharmacologyInteractions
JAK3 3718 CHEMBL2062804 CHEMBL2062804 inhibitor GuideToPharmacologyInteractions
JAK3 3718 DECERNOTINIB CHEMBL3039513 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
JAK3 3718 NS-018 CHEMBL3545217 inhibitor GuideToPharmacologyInteractions
JAK3 3718 PACRITINIB CHEMBL2035187 inhibitor GuideToPharmacologyInteractions
JAK3 3718 TOFACITINIB CITRATE CHEMBL2103743 inhibitor MyCancerGenome, ChemblInteractions
JAK3 3718 ATEZOLIZUMAB CHEMBL3707227 CIViC 26014096
JAK3 3718 AT-9283 CHEMBL495727 inhibitor TALC, GuideToPharmacologyInteractions, ChemblInteractions
JAK3 3718 Cerdulatinib CHEMBL3545284 inhibitor GuideToPharmacologyInteractions, ChemblInteractions
JAK3 3718 TOFACITINIB CHEMBL221959 inhibitor CKB, GuideToPharmacologyInteractions, CIViC, DrugBank, TTD 10592235, 25193870, 26446793, 25146434, 21821710, 22705984
JAK3 3718 FEDRATINIB CHEMBL1287853 inhibitor GuideToPharmacologyInteractions
JAK3 3718 IBRUTINIB CHEMBL1873475 inhibitor GuideToPharmacologyInteractions
JAK3 3718 TASOCITINIB CHEMBL459769 TdgClinicalTrial
JAK3 3718 R-333 CHEMBL3545159 inhibitor ChemblInteractions
JAK3 3718 AZD-1480 CHEMBL1231124 inhibitor GuideToPharmacologyInteractions
JAK3 3718 BMS-911543 CHEMBL3545215 inhibitor GuideToPharmacologyInteractions
JAK3 3718 FILGOTINIB CHEMBL3301607 inhibitor GuideToPharmacologyInteractions
JAK3 3718 PAROXETINE CHEMBL490 inhibitor GuideToPharmacologyInteractions
JAK3 3718 MOMELOTINIB CHEMBL1078178 inhibitor GuideToPharmacologyInteractions
JAK3 3718 XL-019 CHEMBL3545328 inhibitor GuideToPharmacologyInteractions
JAK3 3718 TRICETAMIDE CHEMBL2106468 inhibitor ChemblInteractions
JAK3 3718 WHI-P131 CHEMBL405130 inhibitor ChemblInteractions
JAK3 3718 CHEMBL3116050 CHEMBL3116050 inhibitor GuideToPharmacologyInteractions
JAK3 3718 GANDOTINIB CHEMBL2107823 inhibitor GuideToPharmacologyInteractions
JAK3 3718 PEFICITINIB CHEMBL3137308 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
JAK3 3718 TAK-659 CHEMBL3544931 inhibitor GuideToPharmacologyInteractions
JAK3 3718 R-348 CHEMBL3545382 inhibitor TdgClinicalTrial, ChemblInteractions
JAK3 3718 RUXOLITINIB CHEMBL1789941 inhibitor CKB, GuideToPharmacologyInteractions 26446793

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID