Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ITGB3 3690 TIROFIBAN HYDROCHLORIDE CHEMBL1704 inhibitor ChemblInteractions
ITGB3 3690 EPTIFIBATIDE CHEMBL1174 inhibitor PharmGKB, TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 14617694, 11588534, 12360110, 12928738, 14618072, 10592235, 15860200
ITGB3 3690 DI17E6 CHEMBL2109621 inhibitor ChemblInteractions
ITGB3 3690 TADOCIZUMAB CHEMBL1743076 antagonist ChemblInteractions
ITGB3 3690 GANTOFIBAN CHEMBL78871 TdgClinicalTrial
ITGB3 3690 BELAPERIDONE CHEMBL2105926 TdgClinicalTrial
ITGB3 3690 TIROFIBAN CHEMBL916 antagonist PharmGKB, TdgClinicalTrial, TEND, DrugBank 11752352, 20210689, 10592235
ITGB3 3690 INTETUMUMAB CHEMBL1743032 antagonist TdgClinicalTrial, ChemblInteractions
ITGB3 3690 CILENGITIDE CHEMBL429876 antagonist, inhibitor TALC, TdgClinicalTrial, ChemblInteractions
ITGB3 3690 ETARACIZUMAB CHEMBL1743014 antagonist ChemblInteractions, DrugBank
ITGB3 3690 ABCIXIMAB CHEMBL1201584 antagonist, inhibitor PharmGKB, TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 11588534, 12165285, 18510478, 11752352, 12749745, 17441904
ITGB3 3690 LEFRADAFIBAN CHEMBL2105032 DrugBank 11250974

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ITGB3 rs5918 C aspirin efficacy no Allele C = PIA2, allele T = PIA1. Allele C is not associated with resistance to aspirin or clopidogrel as compared to allele T. 23834376 1184989701
ITGB3 rs5918 C aspirin efficacy no Patients were undergoing elective PCI and were treated with aspirin and clopidogrel. Allele C is not associated with response to aspirin as compared to allele T. 16581111 981848070
ITGB3 rs5918 C clopidogrel efficacy no in Turkish patients who underwent percutaneous coronary interventions with stent implantation. Patients with PRU values >208 were classified as non-responsiveness to clopidogrel therapy. Allele C is not associated with response to clopidogrel as compared to allele T. 28135763 1448633787