Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
IL2RB 3560 DENILEUKIN DIFTITOX CHEMBL1201550 agonist, binder ChemblInteractions, TEND, DrugBank, TTD 17187516, 11752352, 16516670, 15811959, 18684057
IL2RB 3560 DACLIZUMAB CHEMBL1201605 inhibitor, antibody ChemblInteractions, DrugBank, TTD 2647626, 11752352, 2571203, 12372041, 15022409, 15814281
IL2RB 3560 INOLIMOMAB CHEMBL2108370 antagonist TTD
IL2RB 3560 HUMAN INTERLEUKIN-2 CHEMBL1201438 agonist, modulator TdgClinicalTrial, ChemblInteractions, TEND, DrugBank, TTD 16569767, 11752352, 16617454, 16477002, 16542139, 16596189
IL2RB 3560 BASILIXIMAB CHEMBL1201439 inhibitor, antibody ChemblInteractions, DrugBank, TTD 12667677, 11840795, 11752352, 10188761, 12826150, 10708100

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
IL2RB rs3218253 A adalimumab efficacy no Allele A is not associated with response to adalimumab, etanercept, infliximab or Tumor necrosis factor alpha (TNF-alpha) inhibitors in people with Arthritis, Rheumatoid as compared to allele G. 23007924 981417573