PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
EGFR	5	RASA1	3	pull down, unspecified method, pull down	Daly RJ (1996), Jones RB (2006), Marengere LE (1992)	3
TTYH2	2	GRM1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTPN11	20	JAK1	6	pull down, enzymatic study, affinity chromatography technology	Yin T (1997), Yin T (1997), Lehmann U (2003)	3
IGF1R	5	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SHC1	0	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
DUSP18	0	PTPN6	0	affinity chromatography technology	St-Denis N (2016)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
ARRB1	2	CSK	3	affinity chromatography technology, affinity chromatography technology	Miller WE (2000), Lodeiro M (2009)	2
CBL	7	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanaka Y (2008), Tanaka Y (2008), Hoff H (2007), Chernock RD (2001), Chernock RD (2001)	5
FGFR4	6	PTPN11	20	two hybrid	Yao Z (2017)	1
ARRB1	2	JAK1	6	affinity chromatography technology	Ewing RM (2007)	1
UBQLN1	1	APP	1	two hybrid, affinity chromatography technology, fluorescent resonance energy transfe	Stieren ES (2011), Stieren ES (2011), Hiltunen M (2006)	3
ERBB2	6	STYX	1	two hybrid	Yao Z (2017)	1
PIK3R1	6	IRS1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology	Hadari YR (1992), Morrison KB (2002), Gual P (2003), Hamer I (2002), Bazuine M (2003), Tzatsos A (2006), Calegari VC (2005), Tzatsos A (2009), Liu BA (2012), Sung CK (1994), Ren W (2013), Sung CK (1998), Grossmann A (2015), Grossmann A (2015), Antonetti DA (1996), Luo M (2007), Luo M (2007)	17
ERBB2	6	THRSP	0	two hybrid	Arroyo R (2015)	1
IRS1	7	APP	1	pull down	Olah J (2011)	1
HNRNPL	3	APP	1	affinity chromatography technology	Fei T (2017)	1
IGF1R	5	PPM1F	1	affinity chromatography technology	Yao Z (2017)	1
CSK	3	RASA1	3	pull down	Neet K (1995)	1
CDKN2A	1	HSP90AA1	7	pull down	Souza-Rodrigues E (2007)	1
PTK2	2	TP53	0	affinity chromatography technology, pull down, imaging technique	Lim ST (2008), Lim ST (2008), Chen TC (2014)	3
HNRNPL	3	IGF1R	5	affinity chromatography technology	Fei T (2017)	1
ERBB2	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology	Schulze WX (2006), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Vogel W (1996)	5
CSK	3	IGF1R	5	two hybrid, affinity chromatography technology	Arbet-Engels C (1999), Arbet-Engels C (1999)	2
GRM1	4	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RELA	1	TP53	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Huang WC (2007), Huang WC (2007), Ivanov AA (2017)	3
ARRB1	2	YWHAG	5	affinity chromatography technology	Xiao K (2007)	1
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
IGF1R	5	MPZL2	0	affinity chromatography technology	Yao Z (2017)	1
SLAMF1	2	IGF1R	5	affinity chromatography technology	Huttlin EL (2017)	1
PTPN12	2	SHC1	0	two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Habib T (1994), Charest A (1996), Charest A (1996), Habib T (1994), Habib T (1994), Brehme M (2009), Li J (2013), St-Denis N (2016), St-Denis N (2016), Huttlin EL (2017)	10
NTRK1	1	PTPRR	3	affinity chromatography technology, two hybrid	Emdal KB (2015), Yao Z (2017)	2
CDKN1B	1	YWHAE	0	affinity chromatography technology, pull down	Sekimoto T (2004), Sekimoto T (2004)	2
ARRB2	5	YWHAG	5	affinity chromatography technology	Xiao K (2007)	1
GRM1	4	IGF1R	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HNRNPL	3	ARRB1	2	affinity chromatography technology	Fei T (2017)	1
UNC5CL	5	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
HNRNPL	3	SH2B1	7	affinity chromatography technology	Fei T (2017)	1
NAT2	0	KLK5	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTOR	14	PRKDC	12	genetic interference	Shen JP (2017)	1
NTRK1	1	RELA	1	affinity chromatography technology	Emdal KB (2015)	1
KDELR2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IRS1	7	SOCS3	0	affinity chromatography technology, affinity chromatography technology	Calegari VC (2005), Calegari VC (2005)	2
CRKL	1	PXN	1	affinity chromatography technology, pull down, affinity chromatography technology	Salgia R (1995), Salgia R (1995), Nishiya N (2001)	3
GRM1	4	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NTRK1	1	PTPN12	2	affinity chromatography technology	Emdal KB (2015)	1
NEDD4	2	RUVBL1	2	pull down	Ingham RJ (2005)	1
IGF1R	5	ILKAP	2	two hybrid	Yao Z (2017)	1
ESR1	0	RPL11	3	affinity chromatography technology	Tarallo R (2011)	1
HSP90AA1	7	PRKDC	12	affinity chromatography technology	Falsone SF (2005)	1
HSP90AA1	7	ERBB2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu W (2001), Jeong JH (2008), Mollapour M (2010), Citri A (2002), Jung Y (2007), Suzuki T (2011), Tsutsumi S (2012), Taipale M (2012), Bali P (2005), Woodford MR (2016), Yan YY (2011), Yan YY (2011)	12
TRIM25	5	HSP90AA1	7	affinity chromatography technology	Choudhury NR (2017)	1
APP	1	RPL11	3	pull down	Virok DP (2011)	1
PTPN11	20	SOCS3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lehmann U (2003), Lehmann U (2003), Schmitz J (2000), Orr SJ (2007)	4
CHEK1	2	RELA	1	enzymatic study	Rocha S (2005)	1
IGF1R	5	SYVN1	2	affinity chromatography technology, affinity chromatography technology	Xu YM (2015), Xu YM (2015)	2
YWHAG	5	PIK3R1	6	affinity chromatography technology	Jin J (2004)	1
ERBB2	6	STAT3	0	affinity chromatography technology, unspecified method	Ren Z (2002), Jones RB (2006)	2
DUSP21	0	APP	1	pull down	Olah J (2011)	1
MDM2	2	ARRB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Wang P (2003), Shenoy SK (2008), Girnita L (2005), Girnita L (2005), Nogues L (2011), Shenoy SK (2001), Ahmed MR (2011)	7
PXN	1	PIK3R1	6	imaging technique	Chen TC (2014)	1
HSP90AA1	7	CDK4	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsutsumi S (2012), Wang H (2002), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Woodford MR (2016), Huttlin EL (2017)	7
TTYH2	2	KDELR2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	THRSP	0	two hybrid	Arroyo R (2015)	1
ILKAP	2	CHEK1	2	enzymatic study	Zhang X (2017)	1
EGFR	5	EHD1	5	affinity chromatography technology	Tong J (2014)	1
CSK	3	SHC1	0	pull down, affinity chromatography technology	Sato K (2002), Brehme M (2009)	2
EGFR	5	YWHAB	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
EGFR	5	PTPN6	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Tomic S (1995), Keilhack H (1998), Keilhack H (1998), Yao Z (2017)	4
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
IRS1	7	SH2B1	7	unspecified method	Liu BA (2012)	1
ERBB2	6	ILKAP	2	two hybrid	Yao Z (2017)	1
HDAC6	0	PTPN11	20	affinity chromatography technology	M L (2016)	1
NTRK1	1	YWHAE	0	affinity chromatography technology	Emdal KB (2015)	1
FBXO6	0	HNRNPL	3	affinity chromatography technology	Liu B (2012)	1
PTPN7	3	APP	1	pull down	Olah J (2011)	1
ARRB1	2	YWHAB	1	affinity chromatography technology	Xiao K (2007)	1
IGF1R	5	RPL11	3	two hybrid	Wang J (2011)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
ARRB1	2	HSP90AA1	7	affinity chromatography technology	Xiao K (2007)	1
JAK1	6	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Ueda T (2002), Spiekermann K (2001), Andl CD (2004)	3
PIK3R3	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
TTYH2	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTK2	2	MDM2	2	pull down	Lim ST (2008)	1
IGF1R	5	CAMP	0	pull down, affinity chromatography technology	Girnita A (2011), Girnita A (2011)	2
GRB10	4	YWHAE	0	pull down, affinity chromatography technology, affinity chromatography technology	Urschel S (2005), Urschel S (2005), Urschel S (2005)	3
NTRK1	1	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Takahashi Y (2011), Emdal KB (2015), Emdal KB (2015)	3
NTRK1	1	PHB2	1	affinity chromatography technology	Emdal KB (2015)	1
HNRNPL	3	PTK2	2	affinity chromatography technology	Fei T (2017)	1
PXN	1	HDAC6	0	imaging technique, fluorescent resonance energy transfe, affinity chromatography technology	Deakin NO (2014), Deakin NO (2014), Deakin NO (2014)	3
ARRB2	5	RPL11	3	affinity chromatography technology	Xiao K (2007)	1
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
SOCS3	0	RELA	1	affinity chromatography technology, affinity chromatography technology	Nair S (2011), Nair S (2011)	2
STAT3	0	PIK3R3	0	two hybrid	Grossmann A (2015)	1
RACK1	2	JAK1	6	affinity chromatography technology, pull down, affinity chromatography technology	Usacheva A (2003), Usacheva A (2003), Renga B (2012)	3
ESR1	0	PRKDC	12	affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Tarallo R (2011)	2
IGF1R	5	IGF1	0	pull down	Kjeldsen T (1991)	1
MTOR	14	RUVBL1	2	affinity chromatography technology	Agrawal P (2012)	1
CDK4	2	CDKN2A	1	affinity chromatography technology, unspecified method, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Fahraeus R (1996), Li J (2004), Sugimoto M (1999), Serrano M (1993), Serrano M (1993), Serrano M (1993), Coleman KG (1997), Zhang Y (1998), Haddad MM (1999), Li J (2002), Li J (2002), Lal G (2000), Yarbrough WG (1999), Della Torre G (2001), Jones R (2007), Jones R (2007), Ramachandran N (2004), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Fei HJ (2017), Huttlin EL (2017), Ivanov AA (2017)	25
HSP90AA1	7	PTK2	2	affinity chromatography technology	Taipale M (2012)	1
IGF1R	5	DUSP26	0	two hybrid	Yao Z (2017)	1
TP53	0	HNRNPL	3	affinity chromatography technology	Horikawa I (2014)	1
STAT3	0	CBL	7	two hybrid	Grossmann A (2015)	1
GRB10	4	APP	1	pull down	Olah J (2011)	1
NTRK1	1	HNRNPL	3	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	PRKDC	12	affinity chromatography technology	Choudhury NR (2017)	1
EGFR	5	SH2B1	7	unspecified method, two hybrid, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	3
EGFR	5	PTPN7	3	two hybrid	Yao Z (2017)	1
PTPN6	0	PIK3R1	6	two hybrid	Sathish JG (2001)	1
SSH1	1	YWHAG	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Li X (2016)	2
EGFR	5	ILKAP	2	two hybrid	Yao Z (2017)	1
IGF1R	5	PTPN7	3	two hybrid	Yao Z (2017)	1
PTPN12	2	PXN	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, bioid, affinity chromatography technology	Shen Y (2000), Shen Y (2000), Shen Y (2000), Cote JF (1999), Cote JF (1999), Shen Y (1998), Shen Y (1998), St-Denis N (2016), Huttlin EL (2017)	9
JAK1	6	SOCS3	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down	Park ES (2000), Cohney SJ (1999), Cohney SJ (1999), Cohney SJ (1999)	4
EGFR	5	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ettenberg SA (1999), Tvorogov D (2002), Pennock S (2008), Umebayashi K (2008), Ng C (2008), Ng C (2008), Povlsen GK (2008), Khan EM (2008), Su X (2007), Shtiegman K (2007), Han W (2006), Visser GD (2005), Tsacoumangos A (2005), Prasad NK (2005), Gur G (2004), Kowanetz K (2004), Feshchenko EA (2004), Wu WJ (2003), Schmidt MH (2003), Bao J (2003), Rubin C (2003), Waterman H (1999), Bonaccorsi L (2007), Dey N (2011), Miraoui H (2010), Guo HB (2009), Tong J (2009), Tong J (2009), Sun Q (2010), Sanada F (2009), Rafiq K (2011), Ravid T (2004), Ravid T (2004), Duan L (2011), Duan L (2011), Haglund K (2005), Oksvold MP (2003), Oksvold MP (2003), Gui A (2012), Yang S (2006), de Melker AA (2004), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Raguz J (2007), de Melker AA (2004), Thien CB (2001), Kassenbrock CK (2004), Tarcic G (2009), Schroeder B (2012), Adachi S (2009), Shen F (2007), Mitsushima M (2006), Choi JH (2003), Burke P (2001), Tanaka S (1995), Meisner H (1995), Meisner H (1995), Kumar EA (2012), Tong J (2008), Dou H (2012), Levkowitz G (1999), Levkowitz G (1999), Bode AM (2009), Thomas C (2012), Meijer IM (2013), Chang CC (2012), Chang CC (2012), Smith CJ (2013), Gan Y (2010), Scott RP (2005), Fukazawa T (1996), Fukazawa T (1996), Fukazawa T (1996), Wang L (2013), Hong SY (2013), Sigismund S (2013), Sigismund S (2013), Sigismund S (2013), Meisner H (1997), Odintsova E (2013), Kondratov KA (2010), He Z (2014), Tong J (2014), Balaji K (2012), Kiuchi T (2014), Zhang B (2005), Waterman H (1999), Ha Thi HT (2015), Yao S (2015), Kortuem F (2015), Igloi Z (2015), Song F (2016), Song F (2016), Lin TY (2017), Conte A (2017)	96
EGFR	5	IRS1	7	unspecified method	Jones RB (2006)	1
NTRK1	1	RASA1	3	affinity chromatography technology	Emdal KB (2015)	1
CDKN2A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Zhang Y (2003), Zhang Y (2003), Rizos H (2003), Zhang Y (1998), Zhang Y (1998), Li L (2010), Li L (2010), Kamijo T (1998), Stott FJ (1998), Ivanov AA (2017)	10
TRIM25	5	FDPS	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
IGF1R	5	VPS45	0	two hybrid	Arroyo R (2015)	1
TRIM25	5	ILKAP	2	affinity chromatography technology	Choudhury NR (2017)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
RELA	1	SOCS1	1	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maine GN (2007), Maine GN (2007), Strebovsky J (2011), Strebovsky J (2011), Ryo A (2003), Ryo A (2003), Ryo A (2003)	7
SHC1	0	APP	1	pull down, affinity chromatography technology	Tarr PE (2002), Tarr PE (2002)	2
YWHAE	0	IGF1R	5	two hybrid, pull down	Craparo A (1997), Craparo A (1997)	2
NTRK1	1	CRKL	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	RUVBL1	2	affinity chromatography technology	Emdal KB (2015)	1
SLAMF1	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Howie D (2002), Morra M (2001)	2
HNRNPL	3	SNAP29	1	affinity chromatography technology	Fei T (2017)	1
ESR1	0	GNAI1	10	imaging technique	Watson CS (2012)	1
GRB10	4	EGFR	5	pull down, two hybrid, protein complementation assay	He W (1998), Kotlyar M (2015), Petschnigg J (2014)	3
ESR1	0	HSP90AA1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nair SC (1996), Lee MO (2002), Fan M (2005), Tateishi Y (2004), Fiskus W (2007), Powell E (2010), Suzuki T (2011), Berry NB (2008), Sumanasekera WK (2003), Taipale M (2012), Donley C (2013), Donley C (2013), Dhamad AE (2016)	13
TRIM25	5	UBQLN1	1	affinity chromatography technology	Choudhury NR (2017)	1
PTK2	2	IRS1	7	two hybrid, affinity chromatography technology	Lebrun P (1998), Lebrun P (1998)	2
IRS1	7	PIK3R3	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Xia X (1999), Mothe I (1997), Grossmann A (2015), Grossmann A (2015)	4
IGF1R	5	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
IGF1R	5	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
YWHAE	0	CBL	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Subramanian RR (2001), Taipale M (2014), Taipale M (2014)	3
CHEK1	2	TP53	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study	Tian H (2002), Sengupta S (2004), Tian H (2002), Goudelock DM (2003), Shieh SY (2000)	5
TTYH2	2	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RPL11	3	CDKN2A	1	affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Zhang Y (2003)	2
SYVN1	2	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, enzymatic study, affinity chromatography technology	Wu ZZ (2011), Wu ZZ (2011), Yamasaki S (2007), Yamasaki S (2007), Yamasaki S (2007), Yamasaki S (2007), Yamasaki S (2007), Namba T (2015)	8
EGFR	5	FBXO6	0	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Liu B (2012)	2
TRIM25	5	CBL	7	affinity chromatography technology	Choudhury NR (2017)	1
IGF1R	5	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Dey BR (1996), Santen RJ (2005), Tartare-Deckert S (1995), Song RX (2004), Yoshimaru T (2013)	5
ARRB2	5	CDK4	2	affinity chromatography technology	Xiao K (2007)	1
NTRK1	1	PRKDC	12	affinity chromatography technology	Emdal KB (2015)	1
IGF1R	5	LYPD3	0	two hybrid	Arroyo R (2015)	1
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
NTRK1	1	JAK1	6	affinity chromatography technology	Emdal KB (2015)	1
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
CDKN1B	1	IGF1R	5	genetic interference	Shen JP (2017)	1
NTRK1	1	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Qian X (1998), Borrello MG (1994), Nakamura T (2002), Meakin SO (1999), Koch A (2000), Emdal KB (2015), Emdal KB (2015)	7
FFAR2	2	IGF1R	5	two hybrid	Wang J (2011)	1
RASA1	3	PXN	1	affinity chromatography technology	Shikata Y (1999)	1
PTPN6	0	PTPN12	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Li X (2016)	2
YWHAB	1	YWHAG	5	affinity chromatography technology, biochemical	Couzens AL (2013), Wan C (2015)	2
HSP90AA1	7	CHEK1	2	affinity chromatography technology, pull down, affinity chromatography technology	Ha K (2011), Arlander SJ (2006), Taipale M (2012)	3
PIK3R1	6	GRB10	4	affinity chromatography technology	Deng Y (2003)	1
HDAC6	0	IGF1R	5	genetic interference	Shen JP (2017)	1
HNRNPL	3	YWHAE	0	biochemical, affinity chromatography technology	Wan C (2015), Fei T (2017)	2
PTK2	2	STAT3	0	affinity chromatography technology, imaging technique	Ryu H (2000), Chen TC (2014)	2
ERBB2	6	DUSP19	0	two hybrid	Yao Z (2017)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
NF2	1	PXN	1	pull down	Fernandez-Valle C (2002)	1
VAV3	4	ESR1	0	pull down	Lee K (2008)	1
TP53	0	SLAMF1	2	genetic interference	Xie L (2013)	1
NTRK1	1	SH2B1	7	two hybrid, affinity chromatography technology, two hybrid	Qian X (1998), Qian X (1998), Koch A (2000)	3
HSP90AA1	7	IGF1R	5	affinity chromatography technology	Taipale M (2012)	1
IGF1R	5	MTA3	3	two hybrid	Arroyo R (2015)	1
ERBB2	6	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	CYP17A1	5	two hybrid	Arroyo R (2015)	1
ERBB2	6	DUSP18	0	two hybrid	Yao Z (2017)	1
HNRNPL	3	EGFR	5	affinity chromatography technology	Fei T (2017)	1
PIK3R1	6	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang S (1999), Takahashi Y (1999), Craddock BL (1997), Wu CJ (2000), Wu CJ (2001), Yu WM (2006)	6
PTPN11	20	IRS1	7	pull down, affinity chromatography technology, unspecified method, pull down, enzymatic study	Kuhne MR (1993), Myers MG (1998), Liu BA (2012), Strack V (2002), Strack V (2002)	5
UBQLN1	1	RELA	1	affinity chromatography technology	Hochrainer K (2015)	1
YWHAG	5	IGF1R	5	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Jin J (2004)	2
CRKL	1	PTPN11	20	affinity chromatography technology	Chin H (1997)	1
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
NTRK1	1	YWHAB	1	affinity chromatography technology	Emdal KB (2015)	1
IGF1R	5	PTPN1	2	affinity chromatography technology	Bandyopadhyay D (1997)	1
NTRK1	1	PTK2	2	affinity chromatography technology	Emdal KB (2015)	1
CBL	7	PXN	1	affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Salgia R (1996)	2
TP53	0	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	VAV3	4	unspecified method	Jones RB (2006)	1
SOCS2	1	SOCS1	1	affinity chromatography technology	Wu KL (2007)	1
NTRK1	1	UBQLN1	1	affinity chromatography technology	Emdal KB (2015)	1
IGF1R	5	TP53	0	affinity chromatography technology	Broussas M (2009)	1
MDM2	2	NEDD4	2	unspecified method, enzymatic study, affinity chromatography technology	Burch LR (2004), Xu C (2014), Xu C (2014)	3
MDM2	2	RELA	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Wang J (2011), Heyne K (2013), Heyne K (2013), Heyne K (2013)	4
ERBB2	6	PTPN6	0	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
HDAC6	0	ERBB2	6	protein complementation assay	Deribe YL (2009)	1
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
EGFR	5	IGF1R	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Morgillo F (2006), Riedemann J (2007), Riedemann J (2007)	3
TTYH2	2	IGF1R	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARRB2	5	ARRB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Xiao K (2007), Xiao K (2007), Huttlin EL (2017)	4
EGFR	5	ARRB2	5	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
RPL11	3	STAT3	0	two hybrid	Wang J (2011)	1
RELA	1	CDK4	2	affinity chromatography technology	Veena MS (2014)	1
SOCS1	1	ERBB2	6	unspecified method	Jones RB (2006)	1
ESR1	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Castoria G (2001), Simoncini T (2000), Simoncini T (2000)	3
SH2B1	7	IGF1R	5	two hybrid	Nishi M (2005)	1
PTPN1	2	THRSP	0	two hybrid	Arroyo R (2015)	1
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
EGFR	5	DUSP18	0	affinity chromatography technology	Yao Z (2017)	1
EHD1	5	PRKDC	12	biochemical	Kristensen AR (2012)	1
EGFR	5	STYX	1	two hybrid	Yao Z (2017)	1
IGF1R	5	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	IGF1R	5	genetic interference	Shen JP (2017)	1
EGFR	5	PPM1A	1	affinity chromatography technology, two hybrid	Yao Z (2017), Yao Z (2017)	2
TRIM25	5	PTK2	2	affinity chromatography technology	Choudhury NR (2017)	1
CBL	7	PTPN6	0	affinity chromatography technology	Kant AM (2002)	1
FBXO6	0	PRKDC	12	affinity chromatography technology	Liu B (2012)	1
HNRNPL	3	RASA1	3	affinity chromatography technology	Fei T (2017)	1
TTYH2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CSK	3	PTK2	2	affinity chromatography technology	Bergman M (1995)	1
IGF1R	5	DUSP19	0	two hybrid	Yao Z (2017)	1
TRIM25	5	STAT3	0	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	IGF1R	5	affinity chromatography technology	Emdal KB (2015)	1
IGF1R	5	ARRB2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Broussas M (2009), Girnita L (2005), Girnita L (2005), Zheng H (2012)	4
IGF1R	5	PRKDC	12	genetic interference	Shen JP (2017)	1
TRIM25	5	PTPN11	20	affinity chromatography technology	Choudhury NR (2017)	1
EGFR	5	FDPS	0	affinity chromatography technology	Foerster S (2013)	1
NF2	1	EGFR	5	affinity chromatography technology, fluorescent resonance energy transfe	Guerrero PA (2015), Ivanov AA (2017)	2
CSK	3	ILKAP	2	biochemical	Wan C (2015)	1
TP53	0	EEA1	3	affinity chromatography technology	Kikuchi J (2003)	1
ESR1	0	IRS1	7	affinity chromatography technology, affinity chromatography technology	Morelli C (2003), Morelli C (2003)	2
GRB10	4	NEDD4	2	affinity chromatography technology	Murdaca J (2004)	1
TP53	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	PPM1F	1	two hybrid	Yao Z (2017)	1
SOCS1	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
IGF1R	5	APP	1	pull down	Olah J (2011)	1
EGFR	5	CSK	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
NTRK1	1	STAT3	0	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	PIK3R3	0	unspecified method, two hybrid, imaging technique, protein complementation assay	Jones RB (2006), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014)	4
PTPN1	2	IRS1	7	pull down, affinity chromatography technology	Goldstein BJ (2000), Ravichandran LV (2001)	2
IGF1R	5	PIK3R1	6	imaging technique	Chen TC (2014)	1
RACK1	2	RASA1	3	affinity chromatography technology, pull down	Koehler JA (2001), Koehler JA (2001)	2
ARRB2	5	YWHAE	0	affinity chromatography technology	Xiao K (2007)	1
PRKDC	12	TP53	0	unspecified method, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Kim ST (1999), Goudelock DM (2003), Yavuzer U (1998), Maiti AK (2010), Shieh SY (1997), Chan DW (2000), Kim ST (1999), Sakaguchi K (1998), Borcherds W (2014)	9
IGF1R	5	BAP1	4	two hybrid	Arroyo R (2015)	1
TRIM25	5	MTOR	14	affinity chromatography technology	Choudhury NR (2017)	1
FGFR4	6	PTPN12	2	two hybrid	Yao Z (2017)	1
IGF1R	5	EEA1	3	affinity chromatography technology	Sehat B (2008)	1
PTK2	2	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Manes S (1999), Takahashi A (2011)	2
ESR1	0	RUVBL1	2	affinity chromatography technology	Tarallo R (2011)	1
ARRB2	5	NEDD4	2	affinity chromatography technology, affinity chromatography technology	Shenoy SK (2008), Han SO (2012)	2
CBL	7	IRS1	7	affinity chromatography technology	Ahmed Z (2000)	1
ERBB2	6	KLK5	1	two hybrid	Arroyo R (2015)	1
TRIM25	5	KDELR2	1	affinity chromatography technology	Choudhury NR (2017)	1
ERBB2	6	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scaltriti M (2009), Shtiegman K (2007), Haslekas C (2005), Riedemann J (2007), Burke P (2001), Meijer IM (2011), Chen TC (2014), Li J (2013), Li J (2013), Caiazza F (2010), Caiazza F (2010), Sharif A (2009)	12
TRIM25	5	MDM2	2	affinity chromatography technology	Choudhury NR (2017)	1
FBXO6	0	YWHAG	5	affinity chromatography technology	Liu B (2012)	1
IGF1R	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Manes S (1999), Seely BL (1995), Seely BL (1995), Yao Z (2017)	4
EGFR	5	ARRB1	2	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
FGFR4	6	PTPRR	3	two hybrid	Yao Z (2017)	1
YWHAB	1	IGF1R	5	pull down	Furlanetto RW (1997)	1
HNRNPL	3	PIK3R3	0	affinity chromatography technology	Fei T (2017)	1
HNRNPL	3	KCNIP3	1	affinity chromatography technology	Fei T (2017)	1
SOCS3	0	SOCS2	1	affinity chromatography technology	Tannahill GM (2005)	1
RPL11	3	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Zhang Y (2003), Dai MS (2004), Dai MS (2004), Bursac S (2012), Fogeron ML (2013)	6
MDM2	2	RPL11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Zhang Y (2003), Zhang Y (2003), Dai MS (2008), Dai MS (2006), Dai MS (2004), Dai MS (2004), Dai MS (2004), Dai MS (2004), Yu W (2011), Sasaki M (2011), Sun XX (2010), Sun XX (2010), Jin A (2004), Lindstroem MS (2007), Lindstroem MS (2007), Horn HF (2008), Horn HF (2008), Zhang Q (2011), Zhang Q (2011), Zhang Q (2011), Lohrum MA (2003), Lohrum MA (2003), Deisenroth C (2010), Deisenroth C (2010), Frum R (2007), Sun XX (2007), Sun XX (2007), Bursac S (2012), Bursac S (2012), Donati G (2011), Gilkes DM (2006), Gilkes DM (2006), Cui D (2013), Ebina M (2013), Wang J (2011), Sundqvist A (2009), Kapoor NR (2013), He X (2016), Kayama K (2017)	40
ARRB1	2	NEDD4	2	affinity chromatography technology	Shenoy SK (2008)	1
NAT2	0	APP	1	pull down	Olah J (2011)	1
IGF1R	5	DUSP14	2	two hybrid	Yao Z (2017)	1
TRIM25	5	HNRNPL	3	affinity chromatography technology	Choudhury NR (2017)	1
ARRB2	5	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, two hybrid, affinity chromatography technology	Wang P (2003), Wang P (2003), Wang P (2003), Shenoy SK (2008), Shenoy SK (2001), Ahmed MR (2011), Yin C (2011), Yin C (2011), Yin C (2011), Girnita L (2005), Girnita L (2005), Nogues L (2011), Boularan C (2007), Boularan C (2007), Wang J (2011), Shenoy SK (2001), Zheng M (2015)	17
CDK4	2	PRKDC	12	genetic interference	Shen JP (2017)	1
ARRB1	2	PPM1A	1	affinity chromatography technology, affinity chromatography technology	Xiao K (2007), Xiao K (2007)	2
IGF1R	5	MTOR	14	genetic interference	Shen JP (2017)	1
EGFR	5	PPM1F	1	affinity chromatography technology	Yao Z (2017)	1
CBL	7	ERBB2	6	pull down, affinity chromatography technology	Zhou P (2003), Bisaro B (2016)	2
CDK4	2	CDKN2B	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Rual JF (2005), Stelzl U (2005), Vinayagam A (2011), Xin X (2009), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Ivanov AA (2017)	12
PRKDC	12	CHEK1	2	unspecified method, pull down, genetic interference	Kim ST (1999), Goudelock DM (2003), Shen JP (2017)	3
KDELR2	1	IGF1R	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IGF1	0	IGFBP3	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Liu B (2003), Ueki I (2000), Buckway CK (2001), Buckway CK (2001), Cohen P (1992), Twigg SM (1998), Firth SM (1998)	7
PTPN1	2	STAT3	0	enzymatic study	Lund IK (2005)	1
HSP90AA1	7	CDKN1B	1	genetic interference	Srivas R (2016)	1
EGFR	5	SOCS3	0	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Xia L (2002), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
PTK2	2	ERBB2	6	imaging technique, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Ritch PA (2003), Ritch PA (2003)	3
IGF1R	5	DUSP18	0	two hybrid	Yao Z (2017)	1
PTPN1	2	PHB2	1	affinity chromatography technology	Hein MY (2015)	1
IGF1R	5	RUVBL1	2	biochemical	Havugimana PC (2012)	1
EGFR	5	PTPN11	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, affinity chromatography technology, enzymatic study	Schulze WX (2006), Tomic S (1995), Crovello CS (1998), Jones RB (2006), Yao Z (2017), Kapoor GS (2010), Vogel W (1996)	7
EHD1	5	SNAP29	1	two hybrid, pull down	Rotem-Yehudar R (2001), Rotem-Yehudar R (2001)	2
PXN	1	PTK2	2	affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kovacic-Milivojevic B (2001), Matsuya M (1998), Turner CE (1999), Liu S (2002), Liu S (2002), Mazaki Y (1997), Zheng C (1998), Brown MC (1996), Fujita H (1998), Zhang Z (1999), Wang JF (2000), Ivankovic-Dikic I (2000)	12
TP53	0	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NTRK1	1	RACK1	2	affinity chromatography technology	Emdal KB (2015)	1
SHC1	0	RUVBL1	2	affinity chromatography technology	Brehme M (2009)	1
PIK3R3	0	PIK3R1	6	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	PIK3R1	6	affinity chromatography technology	Emdal KB (2015)	1
CBL	7	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park RK (1999), Gesbert F (1998), Erdreich-Epstein A (1997), Wang Y (1999), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Brizzi MF (1996), Fukazawa T (1996)	9
IGF1R	5	NEDD4	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Vecchione A (2003), Sehat B (2008), Broussas M (2009)	3
YWHAB	1	CDKN1B	1	pull down	Sekimoto T (2004)	1
IGF1R	5	TRIM25	5	two hybrid, affinity chromatography technology	Arroyo R (2015), Choudhury NR (2017)	2
JAK1	6	SOCS1	1	affinity chromatography technology	Park ES (2000)	1
PTK2	2	SOCS3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Le Y (2007), Le Y (2007), Niwa Y (2005), Rolland T (2014)	4
RUVBL1	2	PRKDC	12	affinity chromatography technology	Izumi N (2010)	1
PTPN6	0	PTK2	2	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
ERBB2	6	NAT2	0	two hybrid	Arroyo R (2015)	1
GRB10	4	IGF1R	5	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Vecchione A (2003), Vecchione A (2003), Dey BR (1996), He W (1998), Morrione A (1996), Morrione A (1996), Broussas M (2009)	7
HNRNPL	3	VPS45	0	affinity chromatography technology	Fei T (2017)	1
CRKL	1	SHC1	0	affinity chromatography technology	Chin H (1997)	1
ARRB2	5	YWHAB	1	affinity chromatography technology	Xiao K (2007)	1
YWHAE	0	IRS1	7	pull down, two hybrid	Craparo A (1997), Craparo A (1997)	2
ERBB2	6	SSH1	1	affinity chromatography technology	Yao Z (2017)	1
CDKN2B	0	APP	1	pull down	Olah J (2011)	1
CDKN2B	0	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EGFR	5	MPZL2	0	affinity chromatography technology	Yao Z (2017)	1
ARRB1	2	IGF1R	5	affinity chromatography technology, affinity chromatography technology	Girnita L (2005), Girnita L (2005)	2
IGF1R	5	PXN	1	affinity chromatography technology	Manes S (1999)	1
EGFR	5	DUSP14	2	affinity chromatography technology	Yao Z (2017)	1
ERBB2	6	EEA1	3	affinity chromatography technology	Giri DK (2005)	1
CHEK1	2	FBXO6	0	affinity chromatography technology	Tu Y (2017)	1
IGF1R	5	RACK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hermanto U (2002), He X (2011), He X (2011)	3
ESR1	0	BAP1	4	two hybrid	Arroyo R (2015)	1
SHC1	0	VAV3	4	affinity chromatography technology	Zeng L (2000)	1
NF2	1	IGF1R	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	ESR1	0	affinity chromatography technology, pull down, enzymatic study	Nakajima A (2007), Nakajima A (2007), Nakajima A (2007)	3
JAK1	6	IRS1	7	enzymatic study, affinity chromatography technology	Gual P (1998), Johnston JA (1995)	2
PTPN1	2	VPS45	0	two hybrid	Arroyo R (2015)	1
EGFR	5	DUSP19	0	two hybrid	Yao Z (2017)	1
NF2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXO6	0	PPM1F	1	affinity chromatography technology	Liu B (2012)	1
TRIM25	5	YWHAB	1	affinity chromatography technology	Choudhury NR (2017)	1
IGF1R	5	PTK2	2	affinity chromatography technology	Manes S (1999)	1
ERBB2	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IGF1R	5	FDPS	0	biochemical	Wan C (2015)	1
RELA	1	CDKN2A	1	affinity chromatography technology	Veena MS (2014)	1
CDKN2A	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NTRK1	1	CDK4	2	affinity chromatography technology	Emdal KB (2015)	1
SHC1	0	PRKDC	12	affinity chromatography technology	Brehme M (2009)	1
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
YWHAE	0	YWHAB	1	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical	Bandyopadhyay S (2010), Gloeckner CJ (2007), Couzens AL (2013), Wan C (2015)	4
ERBB2	6	PIK3R3	0	unspecified method	Jones RB (2006)	1
UBQLN1	1	MTOR	14	two hybrid, affinity chromatography technology, two hybrid	Wu S (2002), Wu S (2002), Wu S (2002)	3
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
PTK2	2	EGFR	5	affinity chromatography technology, two hybrid, protein complementation assay	Sieg DJ (2000), Kotlyar M (2015), Petschnigg J (2014)	3
TRIM25	5	YWHAE	0	affinity chromatography technology	Choudhury NR (2017)	1
MDM2	2	IGF1R	5	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Sehat B (2008), Sehat B (2008), Girnita L (2003), Girnita L (2003), Broussas M (2009), Chen TC (2014), Worrall C (2017)	7
KDELR2	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AMY2A	0	IGF1R	5	two hybrid	Wang J (2011)	1
IGF1R	5	NAT2	0	two hybrid	Arroyo R (2015)	1
SHC1	0	PTK2	2	affinity chromatography technology	Hecker TP (2002)	1
NTRK1	1	PTPN11	20	affinity chromatography technology	Emdal KB (2015)	1
UNC5CL	5	RELA	1	affinity chromatography technology	Zhang J (2004)	1
IGF1R	5	THRSP	0	two hybrid	Arroyo R (2015)	1
EGFR	5	PTPRR	3	two hybrid	Yao Z (2017)	1
GRM1	4	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PTK2	2	APP	1	pull down	Olah J (2011)	1
KDELR2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CBL	7	IGF1R	5	enzymatic study, affinity chromatography technology	Sehat B (2008), Sehat B (2008)	2
NTRK1	1	ARHGEF12	2	affinity chromatography technology	Emdal KB (2015)	1
FBXO6	0	IGF1R	5	affinity chromatography technology	Liu B (2012)	1
CBL	7	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid	Gesbert F (1998), Gesbert F (1998), Zhang S (1999), Dufour C (2008), Feshchenko EA (2004), Kassenbrock CK (2002), Fang D (2001), Valiya Veettil M (2011), Miao H (2002), Miao H (2002), Ueno H (1998), Gelkop S (2001), Wang Y (1999), Saci A (2000), Matsuo T (1996), Matsuo T (1996), Jackson JG (2000), Meisner H (1995), Saci A (1999), Saci A (1999), Beckwith M (1996), Beckwith M (1996), Song JJ (2010), Hartley D (1996), Finkelstein LD (2000), Ren SY (2005), Hunter S (1997), Hunter S (1997), Jain SK (1997), Jain SK (1997), Swaminathan G (2007), van Leeuwen JE (1999), Ren SY (2005), Ren SY (2005), Alcazar I (2009), Liu YC (1997), Matsuo T (1996), Matsuo T (1996), Lottin-Divoux S (2006), Kitanaka A (1996), Liu YC (1997), Grossmann AH (2004), Panchamoorthy G (1996), Panchamoorthy G (1996), Chernock RD (2001), Chernock RD (2001), Fukazawa T (1995), Fukazawa T (1995), Brehme M (2009), Hakak Y (2000), Hakak Y (2000), Fukazawa T (1995), Liu Y (1999), Cerboni C (1998), Cerboni C (1998), Momose H (2003), Fukazawa T (1996), Fukazawa T (1996), Bulut GB (2013), Bulut GB (2013), Grossmann A (2015)	61
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
EHD1	5	IGF1R	5	pull down, pull down	Rotem-Yehudar R (2001), Rotem-Yehudar R (2001)	2
IGF1R	5	PTPN12	2	two hybrid	Yao Z (2017)	1
PPM1A	1	CHEK1	2	biochemical	Wan C (2015)	1
ARRB2	5	CSK	3	affinity chromatography technology	Lodeiro M (2009)	1
CDKN2A	1	NAT2	0	two hybrid	Arroyo R (2015)	1
IGF1R	5	KCNIP3	1	two hybrid	Rolland T (2014)	1
TP53	0	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
YWHAB	1	APP	1	pull down	Olah J (2011)	1
IGF1R	5	CRKL	1	imaging technique	Chen TC (2014)	1
ARRB2	5	PPM1A	1	affinity chromatography technology, affinity chromatography technology	Xiao K (2007), Xiao K (2007)	2
NTRK1	1	YWHAG	5	affinity chromatography technology	Emdal KB (2015)	1
RASA1	3	APP	1	pull down	Olah J (2011)	1
FBXO6	0	RACK1	2	affinity chromatography technology	Liu B (2012)	1
ARRB1	2	YWHAE	0	affinity chromatography technology	Xiao K (2007)	1
IGF1R	5	HOXC6	0	two hybrid	Arroyo R (2015)	1
TP53	0	SOCS1	1	affinity chromatography technology, pull down, affinity chromatography technology	Calabrese V (2009), Calabrese V (2009), Calabrese V (2009)	3
MTOR	14	ESR1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Alayev A (2016), Alayev A (2016), Alayev A (2016)	3
HNRNPL	3	NF2	1	affinity chromatography technology	Fei T (2017)	1
CRKL	1	SOCS1	1	two hybrid	Grossmann A (2015)	1
SOCS3	0	RASA1	3	pull down, affinity chromatography technology	Cacalano NA (2001), Cacalano NA (2001)	2
IRS1	7	MTOR	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Ozes ON (2001), Tzatsos A (2006), Tzatsos A (2006)	3
NTRK1	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rao R (2010), Taipale M (2012), Emdal KB (2015)	3
LYPD3	0	PTPN1	2	affinity chromatography technology	Huttlin EL (2015)	1
PTPN12	2	CSK	3	bioid	St-Denis N (2016)	1
LYPD3	0	MTOR	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IGF1R	5	DUSP21	0	two hybrid	Yao Z (2017)	1
HOXC6	0	APP	1	pull down	Olah J (2011)	1
APP	1	YWHAG	5	two hybrid, affinity chromatography technology, unspecified method	Sumioka A (2005), Sumioka A (2005), Sumioka A (2005)	3
CBL	7	PTK2	2	imaging technique, affinity chromatography technology, affinity chromatography technology	Rafiq K (2011), Schmidt MH (2003), Sekine Y (2007)	3
CDK4	2	APP	1	pull down	Olah J (2011)	1
NF2	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IGF1R	5	ESR1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Santen RJ (2005), Song RX (2004), Yoshimaru T (2013)	3
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
HSP90AA1	7	JAK1	6	affinity chromatography technology	Taipale M (2012)	1
NTRK1	1	HDAC6	0	affinity chromatography technology	Emdal KB (2015)	1
PTK2	2	PIK3R1	6	affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guinebault C (1995), Guinebault C (1995), Lee DY (2010), Reddy MA (2000), Reiske HR (2000)	5
IL13RA2	0	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
NF2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBQLN1	1	IGF1R	5	affinity chromatography technology, affinity chromatography technology	Kurlawala Z (2017), Kurlawala Z (2017)	2
NEDD4	2	NTRK1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, affinity chromatography technology	Arevalo JC (2006), Arevalo JC (2006), Arevalo JC (2006), Georgieva MV (2011), Georgieva MV (2011), Persaud A (2009), Persaud A (2009), Emdal KB (2015)	8
IGF1R	5	DUPD1	0	two hybrid	Yao Z (2017)	1
CDK4	2	ERBB2	6	genetic interference, fluorescent resonance energy transfe	Shen JP (2017), Ivanov AA (2017)	2
IGFBP3	1	IGF1R	5	biochemical	Mohseni-Zadeh S (1997)	1
PTPN11	20	PTPN6	0	affinity chromatography technology	Li X (2016)	1
IGF1R	5	PPM1A	1	affinity chromatography technology, two hybrid	Yao Z (2017), Yao Z (2017)	2
SOCS3	0	IGF1R	5	pull down, two hybrid, affinity chromatography technology	Dey BR (2000), Dey BR (2000), Dey BR (2000)	3
IL13RA2	0	JAK1	6	affinity chromatography technology	Huttlin EL (2017)	1
ERBB2	6	PTPRR	3	two hybrid, affinity chromatography technology	Yao Z (2017), Yao Z (2017)	2
FBXO6	0	YWHAE	0	affinity chromatography technology	Liu B (2012)	1
CHEK1	2	MTOR	14	genetic interference, genetic interference, genetic interference	Shen JP (2017), Srivas R (2016), Srivas R (2016)	3
KDELR2	1	GRM1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASA1	3	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Madonna S (2008), Madonna S (2008)	2
IGF1R	5	PIK3R3	0	pull down, affinity chromatography technology, imaging technique	Mothe I (1997), Mothe I (1997), Chen TC (2014)	3
CBL	7	YWHAB	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Robertson H (1997), Robertson H (1997), Robertson H (1997), Subramanian RR (2001), Chernock RD (2001), Brehme M (2009), Couzens AL (2013)	7
HDAC6	0	RELA	1	affinity chromatography technology	Yang CJ (2015)	1
ESR1	0	ERBB2	6	affinity chromatography technology	Yang Z (2004)	1
TTYH2	2	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CSK	3	PXN	1	affinity chromatography technology	Bergman M (1995)	1
UNC5CL	5	IGF1R	5	affinity chromatography technology	Huttlin EL (2017)	1
IRS1	7	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Rui L (2002), Li JY (2007)	2
TTYH2	2	NEDD4	2	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	He Y (2008), He Y (2008), He Y (2008), He Y (2008)	4
ESR1	0	RELA	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Olivier S (2006), Nettles KW (2008), Nettles KW (2008), Rubio MF (2006), Rubio MF (2006)	5
IGF1R	5	ERBB2	6	affinity chromatography technology	Riedemann J (2007)	1
ESR1	0	KLK5	1	two hybrid	Arroyo R (2015)	1
MDM2	2	JAK1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heyne K (2014), Heyne K (2014), Hallenborg P (2016)	3
PTPN1	2	EGFR	5	x-ray crystallography, enzymatic study, two hybrid, protein complementation assay, affinity chromatography technology, pull down, pull down	Sarmiento M (2000), Zhang ZY (1996), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Milarski KL (1993), Milarski KL (1993)	7
ERBB2	6	IRS1	7	unspecified method	Jones RB (2006)	1
ERBB2	6	MPZL2	0	affinity chromatography technology	Yao Z (2017)	1
EGFR	5	ESR1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hitosugi T (2007), Hitosugi T (2007), Yao Z (2017)	3
ESR1	0	PHB2	1	two hybrid, pull down, affinity chromatography technology, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology	Martini PG (2003), Kurtev V (2004), Kurtev V (2004), He B (2008), Martini PG (2000), Yoshimaru T (2013), Yoshimaru T (2013), Kim NH (2015)	8
IGF1R	5	PTPRR	3	two hybrid	Yao Z (2017)	1
CDK4	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HNRNPL	3	PTPRR	3	affinity chromatography technology	Fei T (2017)	1
CHEK1	2	IGF1R	5	genetic interference	Shen JP (2017)	1
HNRNPL	3	KDELR2	1	affinity chromatography technology	Fei T (2017)	1
IGF1R	5	DUSP10	3	two hybrid	Yao Z (2017)	1
IGF1R	5	IL13RA2	0	two hybrid	Arroyo R (2015)	1
ERBB2	6	RASA1	3	unspecified method	Jones RB (2006)	1
NF2	1	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HNRNPL	3	GRB10	4	affinity chromatography technology	Fei T (2017)	1
ERBB2	6	DUSP14	2	two hybrid	Yao Z (2017)	1
IGF1R	5	SNAP29	1	affinity chromatography technology	Rotem-Yehudar R (2001)	1
TRIM25	5	PTPN12	2	affinity chromatography technology	Choudhury NR (2017)	1
KDELR2	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HNRNPL	3	ERBB2	6	affinity chromatography technology	Fei T (2017)	1
IGF1R	5	RASA1	3	affinity chromatography technology, pull down	Seely BL (1995), Seely BL (1995)	2
TRIM25	5	ARHGEF12	2	affinity chromatography technology	Choudhury NR (2017)	1
CDKN1B	1	CDK4	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Cariou S (2000), Guidoboni M (2005), Bustany S (2011), Hsu SP (2008), Radu M (2008), Mori S (1999), Kokontis JM (1998), Orend G (1998), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Mandal M (1998), Larrea MD (2009), Seo DW (2006), Kossatz U (2006), Kossatz U (2006), Mallampalli RK (2013), Varjosalo M (2013), Huttlin EL (2015), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	25
IGF1R	5	SSH1	1	affinity chromatography technology	Yao Z (2017)	1
ESR1	0	MDM2	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down	Liu G (2000), Kinyamu HK (2003), Duong V (2007), Duong V (2007), Duong V (2007), Duong V (2007), Saji S (2001), Saji S (2001)	8
TP53	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SOCS3	0	APP	1	pull down	Olah J (2011)	1
GRB14	1	IGF1R	5	two hybrid	Wang J (2011)	1
TRIM25	5	SSH1	1	affinity chromatography technology	Choudhury NR (2017)	1
VAV3	4	IGF1R	5	affinity chromatography technology	Zeng L (2000)	1
NTRK1	1	PPM1F	1	affinity chromatography technology	Emdal KB (2015)	1
SSH1	1	YWHAB	1	affinity chromatography technology	Li X (2016)	1
GRB10	4	IRS1	7	pull down, affinity chromatography technology	Hansen H (1996), Deng Y (2003)	2
MTOR	14	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Yokogami K (2000), Kusaba H (2005), Yang F (2013)	3
FBXO6	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Liu B (2012), Taipale M (2012)	2
IGF1R	5	SLC23A3	3	affinity chromatography technology	Pilot-Storck F (2010)	1
YWHAB	1	TP53	0	affinity chromatography technology	Lee MK (2007)	1
PTPN1	2	CDK4	2	affinity chromatography technology	Li X (2016)	1
PTPN6	0	JAK1	6	enzymatic study	Yetter A (1995)	1
PTPN1	2	NTRK1	1	unspecified method	Espanel X (2002)	1
IGF1R	5	PHB2	1	affinity chromatography technology	Yoshimaru T (2013)	1
STAT3	0	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu Z (2002), Yu Z (2002), Yoshida Y (2004), Yoshida Y (2004), Dhar K (2013)	5
ESR1	0	STAT3	0	affinity chromatography technology	Wang LH (2001)	1
ERBB2	6	JAK1	6	unspecified method	Jones RB (2006)	1
JAK1	6	IGF1R	5	pull down	Gual P (1998)	1
HNRNPL	3	IGF1	0	affinity chromatography technology	Fei T (2017)	1
FBXO6	0	RUVBL1	2	affinity chromatography technology	Liu B (2012)	1
ERBB2	6	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid	Schulze WX (2006), Wong L (1999), Olayioye MA (1998), Crovello CS (1998), Jones RB (2006), Yao Z (2017)	6
YWHAB	1	IRS1	7	pull down	Kosaki A (1998)	1
FGFR4	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IGF1R	5	STAT3	0	imaging technique	Chen TC (2014)	1
MDM2	2	CDKN2A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Zhang Y (2003), Zhang Y (2003), Zhang Y (2003), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Clark PA (2002), Clark PA (2002), Clark PA (2002), Pomerantz J (1998), Ivanchuk SM (2008), Wang C (2005), Wang X (2001), Midgley CA (2000), Shen J (2011), Li L (2010), Li L (2010), Li X (2011), Woods YL (2004), Bouska A (2008), Lindstroem MS (2007), Lohrum MA (2000), Wang J (2006), Wang J (2006), Wang J (2006), Drago-Ferrante R (2008), Schuster K (2007), Hogan C (2008), Rizos H (2000), Gargano B (2008), Kamijo T (1998), Wang S (2010), Jones R (2007), Stott FJ (1998), Lo D (2014), Pimkina J (2009), Blattner C (2002), Leslie PL (2015), Bothner B (2003), Ivanov AA (2017)	42
GNAI1	10	IGF1R	5	affinity chromatography technology	Hallak H (2000)	1
SSH1	1	YWHAE	0	affinity chromatography technology	St-Denis N (2016)	1
PTK2	2	SOCS2	1	two hybrid	Rual JF (2005)	1
IGF1R	5	DUSP15	5	two hybrid	Yao Z (2017)	1
ESR1	0	RACK1	2	pull down	Nalvarte I (2010)	1
CBL	7	CRKL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid	Alsayed Y (2000), Alsayed Y (2000), Kyono WT (1998), Lin H (2001), Park RK (1998), Taher TE (2002), Sattler M (1997), Erdreich-Epstein A (1999), Erdreich-Epstein A (1999), Sattler M (1997), Sattler M (1997), Gesbert F (1998), Chin H (1997), Feshchenko EA (2004), Izadi KD (1998), de Jong R (1995), de Jong R (1995), Boussiotis VA (1997), Boussiotis VA (1997), Barber DL (1997), Uemura N (1999), Okabe S (2006), Alsayed Y (2000), Alsayed Y (2000), Brenner B (2001), van Leeuwen JE (1999), Ribon V (1996), Bhat A (1997), Bhat A (1997), Huang JY (2000), Chernock RD (2001), Chernock RD (2001), Grossmann AH (2004), Sakamoto H (2004), Nishihara T (2003), Peterson ME (2008), Fukazawa T (1996), Martelli MP (2001), Joshi S (2014), Grossmann A (2015)	40
HNRNPL	3	MTA3	3	affinity chromatography technology	Fei T (2017)	1
TP53	0	YWHAE	0	affinity chromatography technology	Fogeron ML (2013)	1
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
FGFR4	6	PTPN6	0	two hybrid	Yao Z (2017)	1
ERBB2	6	LYPD3	0	two hybrid	Arroyo R (2015)	1
IGF1R	5	CYP17A1	5	two hybrid	Arroyo R (2015)	1
GRM1	4	ERBB2	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KDELR2	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERBB2	6	CRKL	1	unspecified method	Jones RB (2006)	1
EGFR	5	SSH1	1	affinity chromatography technology	Yao Z (2017)	1
NEDD4	2	IRS1	7	pull down	Persaud A (2009)	1
ERBB2	6	PPM1A	1	two hybrid	Yao Z (2017)	1
NTRK1	1	FDPS	0	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	EHD1	5	affinity chromatography technology	Emdal KB (2015)	1
FGFR4	6	MTA3	3	two hybrid	Arroyo R (2015)	1
TP53	0	EGFR	5	genetic interference, genetic interference	Xie L (2013), Ye H (2016)	2
TRIM25	5	RPL11	3	affinity chromatography technology	Choudhury NR (2017)	1
YWHAG	5	YWHAE	0	two hybrid, affinity chromatography technology, two hybrid, biochemical	Bandyopadhyay S (2010), Gloeckner CJ (2007), Wang J (2011), Wan C (2015)	4
GRM1	4	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NEDD4	2	EGFR	5	enzymatic study, pull down	Persaud A (2009), Persaud A (2009)	2
EGFR	5	SOCS1	1	affinity chromatography technology	Xia L (2002)	1
ERBB2	6	PIK3R1	6	affinity chromatography technology, unspecified method	Crovello CS (1998), Jones RB (2006)	2
EGFR	5	PRKDC	12	affinity chromatography technology	Foerster S (2013)	1
STAT3	0	PTPN11	20	affinity chromatography technology, affinity chromatography technology	Gunaje JJ (2001), M L (2016)	2
EGFR	5	PTPN12	2	protein complementation assay, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Yao Z (2017)	5
CBL	7	CSK	3	affinity chromatography technology, affinity chromatography technology	Sanjay A (2001), Brehme M (2009)	2
EGFR	5	MTOR	14	affinity chromatography technology	Foerster S (2013)	1
IGF1R	5	ARHGEF12	2	two hybrid, pull down, affinity chromatography technology	Taya S (2001), Taya S (2001), Taya S (2001)	3
CHEK1	2	APP	1	pull down	Olah J (2011)	1
RELA	1	IGF1R	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HDAC6	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, imaging technique	M L (2016), M L (2016), M L (2016)	3
HDAC6	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Kekatpure VD (2009), Rao R (2008), Bali P (2005), Kovacs JJ (2005), New M (2013), Rao R (2012), Kovacs JJ (2005)	7
LYZL2	0	IGF1R	5	affinity chromatography technology	Huttlin EL (2017)	1
IGF1R	5	KLK5	1	two hybrid	Arroyo R (2015)	1
SOCS1	1	PTPN11	20	affinity chromatography technology	Ali S (2003)	1
ARRB2	5	ARHGEF12	2	affinity chromatography technology	Xiao K (2007)	1
RELA	1	PRKDC	12	affinity chromatography technology	Veena MS (2014)	1
EGFR	5	JAK1	6	affinity chromatography technology	Tong J (2008)	1
PTPN12	2	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
IGF1R	5	IRS1	7	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Tartare-Deckert S (1995), Dey BR (1996), Dey BR (1996), Manes S (1999)	4
ERBB2	6	IL13RA2	0	two hybrid	Arroyo R (2015)	1
CBL	7	PIK3R3	0	two hybrid, two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015), Grossmann A (2015)	3
SHC1	0	ESR1	0	affinity chromatography technology, pull down	Song RX (2002), Song RX (2002)	2
SOCS1	1	IGF1R	5	two hybrid	Dey BR (1998)	1
HNRNPL	3	ARRB2	5	affinity chromatography technology	Fei T (2017)	1
IGF1R	5	STYX	1	two hybrid	Yao Z (2017)	1
NTRK1	1	VPS45	0	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	GRB14	1	pull down, pull down	Daly RJ (1996), Daly RJ (1996)	2
VAV3	4	EGFR	5	affinity chromatography technology, affinity chromatography technology	Moores SL (2000), Tong J (2014)	2
SOCS2	1	IGF1R	5	two hybrid, pull down, affinity chromatography technology	Dey BR (1998), Dey BR (1998), Dey BR (1998)	3
NEDD4	2	HNRNPL	3	pull down	Ingham RJ (2005)	1
APP	1	SYVN1	2	affinity chromatography technology, enzymatic study	Kaneko M (2010), Kaneko M (2010)	2
MTOR	14	TP53	0	affinity chromatography technology, genetic interference	Su WC (2009), Ye H (2016)	2