Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
IGF1R 3480 XL-228 CHEMBL3545085 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, DrugBank
IGF1R 3480 CHEMBL464552 CHEMBL464552 inhibitor GuideToPharmacologyInteractions
IGF1R 3480 CHEMBL458997 CHEMBL458997 inhibitor GuideToPharmacologyInteractions
IGF1R 3480 KW-2450 CHEMBL3545156 inhibitor ChemblInteractions
IGF1R 3480 MECASERMIN CHEMBL1201716 agonist, inhibitor TdgClinicalTrial, ChemblInteractions, TEND, TTD
IGF1R 3480 MECASERMIN RINFABATE CHEMBL1201717 agonist ChemblInteractions
IGF1R 3480 GANITUMAB CHEMBL1743024 antagonist, inhibitor, antibody TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, CancerCommons, TTD
IGF1R 3480 BMS-754807 CHEMBL575448 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
IGF1R 3480 LINSITINIB CHEMBL1091644 inhibitor TALC, MyCancerGenome, TdgClinicalTrial, ClearityFoundationClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, CancerCommons
IGF1R 3480 DALOTUZUMAB CHEMBL1743006 antagonist, inhibitor, antibody TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, TTD
IGF1R 3480 CIXUTUMUMAB CHEMBL1743001 antagonist, antibody TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, DrugBank, CancerCommons
IGF1R 3480 RINFABATE CHEMBL2108047 DrugBank
IGF1R 3480 CHEMBL401930 CHEMBL401930 inhibitor MyCancerGenome, GuideToPharmacologyInteractions
IGF1R 3480 BRIGATINIB CHEMBL3545311 inhibitor GuideToPharmacologyInteractions
IGF1R 3480 AVE-1642 CHEMBL2109357 antagonist, antibody TALC, ChemblInteractions
IGF1R 3480 ROBATUMUMAB CHEMBL1743064 antagonist, antibody TALC, ChemblInteractions
IGF1R 3480 ERLOTINIB CHEMBL553 CGI
IGF1R 3480 PICROPODOPHYLLOTOXIN CHEMBL283120 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions
IGF1R 3480 CHEMBL1230989 CHEMBL1230989 DrugBank 17139284, 17016423
IGF1R 3480 INSM-18 CHEMBL3545025 inhibitor TdgClinicalTrial, ChemblInteractions, DrugBank
IGF1R 3480 CHEMBL263143 CHEMBL263143 DrugBank 10592235
IGF1R 3480 EMACTUZUMAB CHEMBL3545370 antibody GuideToPharmacologyInteractions
IGF1R 3480 PL-225B CHEMBL3545004 inhibitor ChemblInteractions
IGF1R 3480 TEPROTUMUMAB CHEMBL1743079 antagonist, inhibitor ChemblInteractions, TTD
IGF1R 3480 RALOXIFENE CHEMBL81 NCI 14533013
IGF1R 3480 AEW-541 CHEMBL551064 inhibitor GuideToPharmacologyInteractions, ChemblInteractions, TTD
IGF1R 3480 INSULIN HUMAN CHEMBL1201631 DrugBank 17139284, 17016423
IGF1R 3480 CHEMBL397666 CHEMBL397666 DrugBank 10592235
IGF1R 3480 AZD-4547 CHEMBL3184679 inhibitor GuideToPharmacologyInteractions
IGF1R 3480 CERITINIB CHEMBL2403108 inhibitor GuideToPharmacologyInteractions
IGF1R 3480 DIMETHISTERONE CHEMBL2106347 inhibitor GuideToPharmacologyInteractions
IGF1R 3480 BIIB-022 CHEMBL2109356 antibody TALC, MyCancerGenome
IGF1R 3480 FIGITUMUMAB CHEMBL1743019 antagonist, inhibitor, antibody TALC, MyCancerGenome, TdgClinicalTrial, ChemblInteractions, TTD
IGF1R 3480 STAUROSPORINE CHEMBL388978 NCI 8895768
IGF1R 3480 INSULIN GLARGINE CHEMBL1201497 agonist DrugBank 20392809
IGF1R 3480 ACETYLCYSTEINE CHEMBL600 NCI 12485928
IGF1R 3480 THROMBIN CHEMBL2108110 NCI 11375274, 7499260

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID