Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
HMGB2	rs6832850	A	Platinum compounds	efficacy	no	No significant association was found between this SNP and response to platinum-based chemotherapy, in any genetic model (i.e. additive (p=0.86), genotypic (p=0.85), dominant (p=0.62) or recessive (p=0.66)). Responders defined as complete or partial remission, non-responders defined as progressive or stable disease. 236 patients had non-small cell lung cancer and 102 had small cell lung cancer.	Allele A is not associated with response to Platinum compounds in people with Lung Neoplasms as compared to allele T.	24684392	1444698898
HMGB2	rs7686909	C	Platinum compounds	efficacy	no	No significant association was found between this SNP and response to platinum-based chemotherapy, in any genetic model (i.e. additive (p=0.87) or dominant (p=0.67)). Responders defined as complete or partial remission, non-responders defined as progressive or stable disease. 236 patients had non-small cell lung cancer and 102 had small cell lung cancer.	Allele C is not associated with response to Platinum compounds in people with Lung Neoplasms as compared to allele T.	24684392	1444698904