PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SHC1	0	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
ALK	8	MEP1B	2	affinity chromatography technology	Crockett DK (2004)	1
PXN	1	MAPK1	1	imaging technique	Chen TC (2014)	1
GRB2	2	HSPD1	0	affinity chromatography technology	Brehme M (2009)	1
ALK	8	CDK9	3	genetic interference	Shen JP (2017)	1
PIK3R1	6	IRS1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology	Hadari YR (1992), Morrison KB (2002), Gual P (2003), Hamer I (2002), Bazuine M (2003), Tzatsos A (2006), Calegari VC (2005), Tzatsos A (2009), Liu BA (2012), Sung CK (1994), Ren W (2013), Sung CK (1998), Grossmann A (2015), Grossmann A (2015), Antonetti DA (1996), Luo M (2007), Luo M (2007)	17
GRB2	2	HSP90AA1	7	affinity chromatography technology	Brehme M (2009)	1
HSP90AA1	7	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Hein MY (2015)	2
STAT3	0	CDK9	3	affinity chromatography technology, affinity chromatography technology, pull down	Giraud S (2004), Giraud S (2004), Giraud S (2004)	3
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
ALK	8	MAP3K1	4	affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004)	2
SRC	2	BCAR1	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Burnham MR (1999), Burnham MR (1999), Wei L (2002), Hsia DA (2003), Kovacic-Milivojevic B (2001), Donaldson JC (2000), Angers-Loustau A (1999), Cabodi S (2004), Modzelewska K (2006), Sawada Y (2006), Riggins RB (2006), Riggins RB (2006)	12
ALK	8	RAD17	2	affinity chromatography technology	Crockett DK (2004)	1
MAPK8IP3	9	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Matsuura H (2002), Matsuura H (2002), Matsuura H (2002), Matsuura H (2002), Song JJ (2004)	5
ALK	8	TUBB4B	6	affinity chromatography technology	Ambrogio C (2005)	1
SRC	2	RACK1	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chang BY (1998), Chang BY (1998), Chang BY (1998), Chang BY (1998), Chen S (2008)	5
SHC1	0	MYH9	19	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
GRB2	2	TUBB4B	6	affinity chromatography technology	Brehme M (2009)	1
CDK9	3	TUBB4B	6	affinity chromatography technology	Jeronimo C (2007)	1
DUSP19	0	MAPK1	1	affinity chromatography technology	Li X (2016)	1
ALK	8	MYO6	3	affinity chromatography technology	Ambrogio C (2005)	1
MYLK	3	SRC	2	affinity chromatography technology	Garcia JG (1999)	1
HSP90AA1	7	EPHA1	5	affinity chromatography technology	Taipale M (2012)	1
ALK	8	FLII	11	affinity chromatography technology	Ambrogio C (2005)	1
PXN	1	PIK3R1	6	imaging technique	Chen TC (2014)	1
JAK2	1	MAP3K5	1	affinity chromatography technology, enzymatic study	Yu L (2009), Yu L (2009)	2
ALK	8	MYH10	9	affinity chromatography technology	Ambrogio C (2005)	1
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
ALK	8	JAK3	3	affinity chromatography technology, affinity chromatography technology	Zamo A (2002), Crockett DK (2004)	2
ALK	8	MAP3K5	1	affinity chromatography technology	Crockett DK (2004)	1
ERRFI1	1	ACTB	8	affinity chromatography technology	Li J (2013)	1
HSP90AA1	7	STAT3	0	affinity chromatography technology	Sato N (2003)	1
GRB2	2	PIK3CB	2	affinity chromatography technology, affinity chromatography technology	Bisson N (2011), Huttlin EL (2017)	2
MAP2K7	5	MAP3K5	1	affinity chromatography technology	Zama T (2002)	1
ALK	8	MAP2K7	5	affinity chromatography technology	Crockett DK (2004)	1
SRC	2	MAPK8IP3	9	enzymatic study	Takino T (2002)	1
HSP90AA1	7	TUBB4B	6	affinity chromatography technology	Skarra DV (2011)	1
ALK	8	SMC6	3	affinity chromatography technology	Crockett DK (2004)	1
JAK3	3	STAT3	0	affinity chromatography technology	Doucet C (2002)	1
CDK9	3	HSPD1	0	affinity chromatography technology	Jeronimo C (2007)	1
GRB2	2	BCAR1	6	affinity chromatography technology, pull down, affinity chromatography technology	Wang X (2000), Angers-Loustau A (1999), Ambrogio C (2005)	3
PIK3R1	6	JAK2	1	pull down, genetic interference	Ren SY (2005), Shen JP (2017)	2
ALK	8	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004), Bai RY (1998), Ambrogio C (2005), Ambrogio C (2005)	5
RACK1	2	PLCG1	6	far western blotting	Disatnik MH (1994)	1
ALK	8	PXN	1	affinity chromatography technology	Ambrogio C (2005)	1
STAT3	0	PIK3R1	6	two hybrid	Grossmann A (2015)	1
SHC1	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
GRB2	2	SOCS1	1	pull down	De Sepulveda P (1999)	1
STAT3	0	MAPK1	1	affinity chromatography technology	Lo RK (2006)	1
JAK2	1	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Chauhan D (1995), Chauhan D (1995), Giorgetti-Peraldi S (1995), Brizzi MF (1996)	4
MAPK1	1	SHC1	0	affinity chromatography technology	Dinerstein-Cali H (2000)	1
ALK	8	STAT3	0	affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004)	2
SHC1	0	MYH10	9	affinity chromatography technology	Brehme M (2009)	1
ALK	8	VIM	0	affinity chromatography technology	Ambrogio C (2005)	1
PIK3R1	6	MAP3K5	1	affinity chromatography technology, affinity chromatography technology	Xie D (2009), Xie D (2009)	2
ALK	8	CDK13	18	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	PLCB2	0	affinity chromatography technology	Crockett DK (2004)	1
ERRFI1	1	ALK	8	affinity chromatography technology	Pao-Chun L (2009)	1
GRB2	2	ACTB	8	affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Li J (2013)	2
ALK	8	ACTN4	4	affinity chromatography technology	Ambrogio C (2005)	1
IRS4	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
IRS1	7	PIK3CB	2	affinity chromatography technology	Kuchay S (2013)	1
MAPK1	1	MAP3K1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study	Karandikar M (2000), Karandikar M (2000), Gallagher ED (2004), Tu Z (2003), Loke J (2014)	5
SRC	2	JAK2	1	affinity chromatography technology	Liang K (2010)	1
IKBKG	0	JAK3	3	pull down	Fenner BJ (2010)	1
ALK	8	CORO1C	2	affinity chromatography technology	Ambrogio C (2005)	1
IKBKG	0	ALK	8	pull down	Fenner BJ (2010)	1
GRB2	2	MAP3K1	4	pull down, affinity chromatography technology, affinity chromatography technology	Pomerance M (1998), Pomerance M (1998), Saito T (2004)	3
ALK	8	GAK	5	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	DUSP19	0	two hybrid	Yao Z (2017)	1
SHC1	0	TUBB4B	6	affinity chromatography technology	Brehme M (2009)	1
TUBGCP2	5	TUBB4B	6	affinity chromatography technology	Fogeron ML (2013)	1
ALK	8	EPHB2	10	affinity chromatography technology	Crockett DK (2004)	1
HSP90AA1	7	PRKCQ	3	affinity chromatography technology	Taipale M (2012)	1
MYH9	19	FLII	11	affinity chromatography technology	Hein MY (2015)	1
MYH9	19	ACTN4	4	affinity chromatography technology	Hein MY (2015)	1
SOCS1	1	PIK3R1	6	two hybrid	Grossmann A (2015)	1
IRS4	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Sano H (2002), Skarra DV (2011)	2
DUSP19	0	CORO1C	2	affinity chromatography technology	Yadav L (2017)	1
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
CDK13	18	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IRS1	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Skolnik EY (1993), Skolnik EY (1993), Skolnik EY (1993), Morrison KB (2002), Giorgetti-Peraldi S (1995), Liu BA (2012), Bisson N (2011)	7
SRC	2	ERRFI1	1	enzymatic study	Park E (2015)	1
ALK	8	PRKCQ	3	affinity chromatography technology	Crockett DK (2004)	1
MAP3K1	4	MAP2K7	5	affinity chromatography technology, pull down	Tu Z (2003), Takekawa M (2005)	2
ALK	8	BICD2	0	affinity chromatography technology	Ambrogio C (2005)	1
SHC1	0	JAK2	1	pull down, pull down	VanderKuur J (1995), Giordano V (1997)	2
MYH10	9	MYH9	19	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
EIF4B	3	MYH9	19	biochemical	Havugimana PC (2012)	1
MAP2K7	5	MAP3K4	1	pull down	Takekawa M (2005)	1
MAPK8IP3	9	MAP3K1	4	affinity chromatography technology	Ito M (1999)	1
IRS1	7	ALK	8	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	HSPD1	0	affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004)	2
ALK	8	MTIF2	4	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	KRT18	2	affinity chromatography technology	Crockett DK (2004)	1
HSP90AA1	7	MYH9	19	affinity chromatography technology	Falsone SF (2005)	1
PIK3R1	6	ALK	8	pull down	Ren SY (2005)	1
MAPK1	1	MAP2K7	5	unspecified method, enzymatic study, enzymatic study	Ho DT (2006), Mori S (1995), Saito T (2004)	3
TNK2	7	ALK	8	affinity chromatography technology	Pao-Chun L (2009)	1
SOCS1	1	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	He Y (2006), He Y (2006), He Y (2006), Kolliputi N (2009), Kolliputi N (2009)	5
ALK	8	IRF7	2	affinity chromatography technology	Crockett DK (2004)	1
GAK	5	TNK2	7	affinity chromatography technology	Hein MY (2015)	1
GRB2	2	VIM	0	two hybrid	Wang J (2011)	1
ALK	8	PIK3CB	2	affinity chromatography technology	Crockett DK (2004)	1
JAK2	1	PLCG1	6	affinity chromatography technology	Chang YJ (2004)	1
MYH9	19	MYLK	3	affinity chromatography technology	Hein MY (2015)	1
DUSP19	0	ACTB	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IRS4	2	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fantin VR (1998), Bisson N (2011), Bisson N (2011)	3
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
JAK2	1	HSP90AA1	7	affinity chromatography technology	Cheng MB (2010)	1
SHC1	0	PLCG1	6	affinity chromatography technology	Fixman ED (1996)	1
JAK2	1	STAT3	0	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Ram PA (1997), Manea A (2010), Andl CD (2004), Kamakura S (2004), He K (2013), Kucia-Tran JA (2016), M L (2016)	7
ALK	8	EPHA1	5	affinity chromatography technology, affinity chromatography technology	Crockett DK (2004), Crockett DK (2004)	2
SHC1	0	CORO1C	2	affinity chromatography technology	Brehme M (2009)	1
MYH9	19	CORO1C	2	affinity chromatography technology	Hein MY (2015)	1
PLCG1	6	ALK	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bonvini P (2002), Crockett DK (2004), Crockett DK (2004), Bai RY (1998), Bai RY (1998)	5
ALK	8	EIF4B	3	affinity chromatography technology	Crockett DK (2004)	1
SRC	2	PXN	1	pull down	Angers-Loustau A (1999)	1
ALK	8	SOCS1	1	affinity chromatography technology	Crockett DK (2004)	1
DUSP19	0	MAP3K5	1	affinity chromatography technology, genetic interference	Zama T (2002), Zama T (2002)	2
GRB2	2	PXN	1	pull down	Angers-Loustau A (1999)	1
ALK	8	JAK2	1	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	MAP3K4	1	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	RACK1	2	affinity chromatography technology	Ambrogio C (2005)	1
ALK	8	PDX1	2	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	CENPF	5	affinity chromatography technology	Crockett DK (2004)	1
PLCG1	6	SRC	2	affinity chromatography technology	Dhar A (1994)	1
JAK2	1	SOCS1	1	two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yasukawa H (1999), Dif F (2001), Endo TA (1997), Endo TA (1997), Endo TA (1997), Yasukawa H (1999), Yasukawa H (1999), Pezet A (1999), Ungureanu D (2002), Masuhara M (1997), Ali S (2003), Monni R (2001), Monni R (2001), Piessevaux J (2008), Yu L (2009), Maruoka M (2017)	16
ALK	8	SHC1	0	affinity chromatography technology	Bonvini P (2002)	1
ALK	8	TUBGCP2	5	affinity chromatography technology	Ambrogio C (2005)	1
GRB2	2	ERRFI1	1	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bisson N (2011), Wang J (2011), Wang J (2011), Li J (2013), Li J (2013), Ying H (2010), Huttlin EL (2017)	8
TNK2	7	GRB2	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Satoh T (1996), Kato-Stankiewicz J (2001), Bandyopadhyay S (2010), Lin Q (2010), Lin Q (2012), Yeow-Fong L (2005), Chan W (2011), Yokoyama N (2003), Huttlin EL (2017), Mahendrarajah N (2017)	10
ALK	8	MYLK	3	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	SRC	2	affinity chromatography technology	Ambrogio C (2005)	1
TNK2	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mahajan NP (2005), Mahajan NP (2005), Taipale M (2012), Gao B (2013), Mahendrarajah N (2017), Mahendrarajah N (2017), Mahendrarajah N (2017)	7
ALK	8	PPM1A	1	two hybrid	Yao Z (2017)	1
JAK3	3	JAK2	1	affinity chromatography technology	Doucet C (2002)	1
ALK	8	UBASH3A	3	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	MAPK1	1	affinity chromatography technology	Crockett DK (2004)	1
SRC	2	IKBKG	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Funakoshi-Tago M (2005), Funakoshi-Tago M (2005), Lee SH (2012)	3
SRC	2	TNK2	7	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Chan W (2009), Modzelewska K (2006), Chan W (2011), Chan W (2011), Chan W (2011), Yokoyama N (2003)	6
ALK	8	MAPK8IP3	9	affinity chromatography technology	Crockett DK (2004)	1
HSPD1	0	TUBB4B	6	biochemical	Wan C (2015)	1
ALK	8	IRS4	2	affinity chromatography technology	Crockett DK (2004)	1
IRS1	7	JAK3	3	affinity chromatography technology	Johnston JA (1995)	1
PIK3CB	2	PIK3R1	6	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique	Hu P (1994), Havugimana PC (2012), Sun M (2010), Wan C (2015), Hein MY (2015), Chen TC (2014)	6
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
BCAR1	6	PXN	1	affinity chromatography technology, affinity chromatography technology	Salgia R (1996), Chellaiah MA (2001)	2
HSP90AA1	7	MAP2K7	5	affinity chromatography technology	Taipale M (2012)	1
ALK	8	MYBPC2	5	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	SOCS5	0	affinity chromatography technology	Crockett DK (2004)	1
ALK	8	MYH9	19	affinity chromatography technology	Ambrogio C (2005)	1
IRS1	7	SOCS1	1	affinity chromatography technology, affinity chromatography technology	Rui L (2002), Li JY (2007)	2
MYH9	19	MYO6	3	affinity chromatography technology	Hein MY (2015)	1
DUSP19	0	MAP2K7	5	affinity chromatography technology, pull down	Zama T (2002), Zama T (2002)	2
CDK9	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	5
RACK1	2	PTN	0	two hybrid	Stelzl U (2005)	1
SRC	2	EPHB2	10	two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, pull down	Zisch AH (1998), Zisch AH (2000), Zisch AH (2000), Zisch AH (1998), Zisch AH (1998), Zisch AH (1998)	6
HSP90AA1	7	ALK	8	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
FLII	11	KRT18	2	biochemical	Kristensen AR (2012)	1
MYH9	19	ACTB	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohlstedt K (2006), Hein MY (2015), Chiu HC (2012)	3
SRC	2	MAPK1	1	affinity chromatography technology	Lee J (2013)	1
HSP90AA1	7	FLII	11	affinity chromatography technology	Gano JJ (2010)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
ACTB	8	CORO1C	2	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
ALK	8	PDLIM3	2	affinity chromatography technology	Ambrogio C (2005)	1
TNK2	7	BCAR1	6	affinity chromatography technology, affinity chromatography technology	Modzelewska K (2006), Modzelewska K (2006)	2
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
MAPK1	1	ZC3HC1	1	enzymatic study	Illert AL (2012)	1
IKBKG	0	JAK2	1	pull down	Fenner BJ (2010)	1
JAK2	1	IRS1	7	enzymatic study, affinity chromatography technology	Gual P (1998), Kawazoe Y (2001)	2
ALK	8	BCAR1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ambrogio C (2005), Ambrogio C (2005), Ambrogio C (2005)	3
ALK	8	ZC3HC1	1	pull down, affinity chromatography technology, enzymatic study	Ouyang T (2003), Ouyang T (2003), Ouyang T (2003)	3
GRB2	2	KRT18	2	affinity chromatography technology	Blagoev B (2003)	1
SHC1	0	SRC	2	pull down	Schueller AC (2008)	1
IKBKG	0	KRT18	2	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
ALK	8	KRT74	7	affinity chromatography technology	Crockett DK (2004)	1
PRKCQ	3	IKBKG	0	affinity chromatography technology	Lee KY (2005)	1
ALK	8	SHC3	1	affinity chromatography technology	Miyake I (2002)	1
HSP90AA1	7	MAP3K5	1	affinity chromatography technology	Taipale M (2012)	1
GRB2	2	MYH9	19	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Li J (2013)	2
GAK	5	MYO6	3	affinity chromatography technology	Hein MY (2015)	1
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
IKBKG	0	CDK13	18	affinity chromatography technology	Hein MY (2015)	1
SHC1	0	ACTN4	4	affinity chromatography technology	Brehme M (2009)	1
EPHB2	10	PLCG1	6	two hybrid	Zisch AH (1998)	1
MAP3K1	4	EPHA1	5	enzymatic study	Charlaftis N (2014)	1
ERRFI1	1	SHC1	0	affinity chromatography technology, affinity chromatography technology	Li J (2013), Li J (2013)	2
MAPK8IP3	9	MAP2K7	5	pull down, affinity chromatography technology	Kelkar N (2000), Matsuura H (2002)	2
ALK	8	PTN	0	pull down	Stoica GE (2001)	1
ALK	8	RAB35	0	affinity chromatography technology	Crockett DK (2004)	1
IKBKG	0	CENPF	5	affinity chromatography technology	Huttlin EL (2017)	1
TUBGCP2	5	ACTB	8	affinity chromatography technology	Fogeron ML (2013)	1
CDK13	18	TUBB4B	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ALK	8	ACTB	8	affinity chromatography technology	Ambrogio C (2005)	1