Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ALK 238 CEP-37440 CHEMBL3545051 inhibitor ChemblInteractions
ALK 238 LORLATINIB CHEMBL3286830 CKB, CIViC 27432227, 26144315, 25749034, 26554404, 26698910, 28285684
ALK 238 Delantercept CHEMBL2109662 CKB 26373572, 25888978
ALK 238 ATEZOLIZUMAB CHEMBL3707227 CKB 27225694
ALK 238 CHEMBL464552 CHEMBL464552 inhibitor GuideToPharmacologyInteractions
ALK 238 NAPROXEN CHEMBL154 inhibitor GuideToPharmacologyInteractions
ALK 238 CERITINIB CHEMBL2403108 antagonist, inhibitor CGI, FDA, DrugBank, OncoKB, TALC, CancerCommons, ChemblInteractions, MyCancerGenome, MyCancerGenomeClinicalTrial, CIViC, CKB, DoCM, GuideToPharmacologyInteractions 24670165, 24327273, 26633560, 26933125, 27742657, 17185414, 23742252, 20979472, 23598171, 25322323, 26708155, 26598747, 21502504, 26973324, 27836716, 23724913, 26698910, 24675041, 25228534, 25736571, 26775591, 25749034, 27780853, 25421750, 27432227, 25724526, 27432917, 28126333, 26438117, 25394791, 27009859, 25806224, 22277784, 22235099, 23344087, 20979473, 21575866
ALK 238 ALECTINIB CHEMBL1738797 inhibitor MyCancerGenome, CGI, GuideToPharmacologyInteractions, OncoKB, DrugBank, FDA, TALC, CIViC, CKB 25322323, 24670165, 26708155, 26598747, 21502504, 26973324, 27836716, 23724913, 21575866, 25727400, 22277784, 23639470, 25153538, 25228534, 26938871, 28586279, 27432227, 27565911, 25749034, 25421750, 26698910, 26438117, 28285684, 27009859, 26849637, 23344087, 28455243, 25806224, 25393796
ALK 238 CRIZOTINIB CHEMBL601719 inhibitor MyCancerGenome, TALC, MyCancerGenomeClinicalTrial, CGI, DoCM, GuideToPharmacologyInteractions, CancerCommons, DrugBank, OncoKB, PharmGKB, TdgClinicalTrial, ChemblInteractions, CIViC, CKB 24491302, 2270034, 20979472, 24687827, 22277784, 25228534, 26554404, 22072639, 18923525, 26619011, 21838707, 23598171, 21242967, 18923523, 22235099, 23344087, 24670165, 24327273, 20979473, 21575866, 18724359, 21030459, 21948233, 21791641, 22594847, 25322323, 26708155, 26598747, 21502504, 26973324, 27836716, 23724913, 21258415, 20979469, 26698910, 24675041, 25470694, 24478318, 27022118, 21345110, 23006951, 21933749, 26466010, 25922291, 28586279, 25408655, 18089725, 26221234, 26444240, 27432227, 25749034, 24509625, 27780853, 26438783, 25806224, 25421750, 25724526, 26775591, 27009859, 21613408, 24573551, 28787259
ALK 238 IMATINIB CHEMBL941 NCI 16970400
ALK 238 ENTRECTINIB CHEMBL1983268 OncoKB, CKB, CIViC 28183697, 26939704, 26633560
ALK 238 ALECTINIB HYDROCHLORIDE CHEMBL3707320 inhibitor ChemblInteractions
ALK 238 GANETESPIB CHEMBL2103879 inhibitor MyCancerGenomeClinicalTrial
ALK 238 TAE-684 CHEMBL509032 inhibitor CKB, GuideToPharmacologyInteractions, CIViC 18923525, 22277784, 21494621, 25228534
ALK 238 TOPOTECAN CHEMBL84 CKB 26438783
ALK 238 NIVOLUMAB CHEMBL2108738 CKB 27225694
ALK 238 ADENOSINE TRIPHOSPHATE CHEMBL14249 DrugBank 17139284, 17016423
ALK 238 ASP-3026 CHEMBL3545360 inhibitor MyCancerGenome, CKB, ChemblInteractions, CancerCommons 25228534, 25749034, 25421750, 27009859
ALK 238 CYCLOPHOSPHAMIDE CHEMBL88 CKB 26438783
ALK 238 BRIGATINIB CHEMBL3545311 inhibitor TALC, MyCancerGenome, OncoKB, CKB, GuideToPharmacologyInteractions, ChemblInteractions, CIViC, MyCancerGenomeClinicalTrial, FDA 25727400, 26951079, 28475456, 27049722, 25322323, 24670165, 26708155, 26598747, 21502504, 26973324, 27836716, 23724913, 25228534, 25749034, 27780853, 25421750, 26698910, 27432227, 26438117, 27009859, 24091716
ALK 238 CRENOLANIB CHEMBL2105728 inhibitor MyCancerGenomeClinicalTrial
ALK 238 PEMBROLIZUMAB CHEMBL3137343 CKB 27225694
ALK 238 DURVALUMAB CHEMBL3301587 CKB 27225694
ALK 238 ONALESPIB CHEMBL1214827 CKB
ALK 238 BRENTUXIMAB VEDOTIN CHEMBL1742994 FDA
ALK 238 NVP-AUY922 CHEMBL252164 CKB, CIViC 26698910
ALK 238 X-396 CHEMBL3544934 inhibitor TALC, MyCancerGenome, CKB, ChemblInteractions, CancerCommons 26438117, 21613408
ALK 238 SELUMETINIB CHEMBL1614701 CKB 25394791
ALK 238 SARACATINIB CHEMBL217092 CKB 25394791
ALK 238 DOXORUBICIN CHEMBL53463 CKB, NCI 16880530, 26373572, 28455243
ALK 238 CHEMBL473773 CHEMBL473773 CIViC 17625570
ALK 238 PEMETREXED (CHEMBL1201258) CHEMBL1201258 CIViC 21642865

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID