PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ORC5	0	CDC6	0	pull down	Ramachandran N (2004)	1
XRCC6	3	ORC2	0	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
MCM7	5	ORC6	0	pull down	Ramachandran N (2004)	1
DBF4	2	MCM2	3	two hybrid, enzymatic study	Kneissl M (2003), Masai H (2000)	2
SNW1	0	ORC6	0	affinity chromatography technology	Lleres D (2010)	1
RPA1	0	XRCC5	5	affinity chromatography technology	Marechal A (2014)	1
MCM4	3	ORC5	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
CDC45	1	ORC2	0	two hybrid	Kneissl M (2003)	1
CDC7	2	MCM2	3	two hybrid, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study	Kneissl M (2003), Kneissl M (2003), Gerard A (2006), Martin L (2007), Martin L (2007), Montagnoli A (2006), Suzuki T (2012), Masai H (2000)	8
CDC7	2	MCM6	5	enzymatic study	Masai H (2000)	1
ORC3	3	ORC6	0	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Kneissl M (2003), Kneissl M (2003), Vashee S (2001), Sibani S (2005), Sibani S (2005), Ramachandran N (2004)	6
ORC6	0	LRWD1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DBF4	2	ORC4	1	affinity chromatography technology	Kneissl M (2003)	1
SFPQ	2	PSPC1	2	affinity chromatography technology	Huttlin EL (2017)	1
MCM2	3	MCM7	5	pull down, pull down, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), You Z (1999), Fujita M (1997), You Z (2002), Havugimana PC (2012), Ramachandran N (2004), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Drissi R (2015), Boldt K (2016)	14
ORC6	0	SFPQ	2	affinity chromatography technology	Huttlin EL (2015)	1
MCM5	1	ORC5	0	pull down	Ramachandran N (2004)	1
TERF2	2	MCM7	5	affinity chromatography technology	Giannone RJ (2010)	1
SNW1	0	XRCC6	3	affinity chromatography technology	Lleres D (2010)	1
DCTN6	0	APP	1	pull down	Olah J (2011)	1
MCM2	3	XRCC5	5	affinity chromatography technology	Drissi R (2015)	1
ORC4	1	APP	1	pull down	Olah J (2011)	1
MCM4	3	MCM7	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology	Yabuta N (2003), Fujita M (1997), Ishimi Y (1996), You Z (2002), Havugimana PC (2012), Ramachandran N (2004), Kristensen AR (2012), Wan C (2015), Boldt K (2016)	9
ORC6	0	ORC2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Vashee S (2001), Vashee S (2001), Sibani S (2005), Sibani S (2005), Keller C (2002), Huttlin EL (2015), Huttlin EL (2017)	8
MCM5	1	CDC7	2	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
CDC5L	2	ORC3	3	affinity chromatography technology	Lleres D (2010)	1
DBF4	2	ORC6	0	two hybrid, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003)	2
MCM4	3	CDC7	2	two hybrid, two hybrid, enzymatic study	Kneissl M (2003), Kneissl M (2003), Masai H (2000)	3
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
MCM5	1	CDC5L	2	pull down, affinity chromatography technology	Ramachandran N (2004), Lleres D (2010)	2
TERF2	2	ORC3	3	pull down	Tatsumi Y (2008)	1
SNW1	0	LRWD1	1	affinity chromatography technology	Lleres D (2010)	1
CDC45	1	ORC6	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
MCM6	5	ORC6	0	pull down	Ramachandran N (2004)	1
ORC4	1	ORC5	0	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down	Kneissl M (2003), Kneissl M (2003), Quintana DG (1998), Dhar SK (2001), Ramachandran N (2004)	5
MCM4	3	ORC2	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
CDC45	1	ORC5	0	pull down	Ramachandran N (2004)	1
ORC6	0	PSPC1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDC5L	2	ORC4	1	affinity chromatography technology	Lleres D (2010)	1
SNW1	0	ORC5	0	affinity chromatography technology	Lleres D (2010)	1
MCM5	1	SFPQ	2	affinity chromatography technology	Drissi R (2015)	1
MCM5	1	MCM6	5	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	DaFonseca CJ (2001), Havugimana PC (2012), Wan C (2015), Drissi R (2015)	4
XRCC6	3	TERF2	2	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song K (2000), Song K (2000), Song K (2000), Lee OH (2011), Hein MY (2015)	5
ORC6	0	BICD2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SNW1	0	ORC4	1	affinity chromatography technology	Lleres D (2010)	1
ORC6	0	LHX4	1	two hybrid	Rolland T (2014)	1
LRWD1	1	ORC5	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
RPA1	0	XRCC6	3	affinity chromatography technology	Marechal A (2014)	1
MCM7	5	ORC4	1	pull down	Ramachandran N (2004)	1
ORC4	1	XRCC6	3	affinity chromatography technology	Sibani S (2005)	1
MCM2	3	XRCC6	3	affinity chromatography technology	Drissi R (2015)	1
APP	1	HMGA1	0	pull down	Virok DP (2011)	1
XRCC6	3	HMGA1	0	far western blotting, pull down, affinity chromatography technology	Sgarra R (2008), Sgarra R (2008), Sgarra R (2008)	3
SNW1	0	ORC3	3	affinity chromatography technology	Lleres D (2010)	1
XRCC5	5	ORC3	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Sibani S (2005), Sibani S (2005), Sibani S (2005)	3
MCM4	3	CDC45	1	affinity chromatography technology	Tan BC (2006)	1
ORC2	0	ORC4	1	two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Dhar SK (2001), Quintana DG (1997), Vashee S (2001), Vashee S (2001), Sibani S (2005), Keller C (2002), Ramachandran N (2004), Vermeulen M (2010)	11
ORC5	0	MCM2	3	two hybrid, two hybrid, pull down	Kneissl M (2003), Kneissl M (2003), Ramachandran N (2004)	3
MCM4	3	ORC6	0	two hybrid, two hybrid, pull down	Kneissl M (2003), Kneissl M (2003), Ramachandran N (2004)	3
CREB1	1	HMGA1	0	affinity chromatography technology	Li X (2015)	1
ORC5	0	ORC6	0	two hybrid	Kneissl M (2003)	1
XRCC6	3	ORC6	0	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
CDC6	0	ORC3	3	pull down	Ramachandran N (2004)	1
DBF4	2	ORC5	0	two hybrid	Kneissl M (2003)	1
RPA1	0	MCM6	5	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
CDC6	0	MCM5	1	affinity chromatography technology	Hubbi ME (2013)	1
RPA1	0	SFPQ	2	affinity chromatography technology	Marechal A (2014)	1
TERF2	2	ORC6	0	pull down	Tatsumi Y (2008)	1
MCM5	1	MCM4	3	affinity chromatography technology, biochemical, biochemical	DaFonseca CJ (2001), Havugimana PC (2012), Wan C (2015)	3
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
CDC5L	2	ORC2	0	pull down, affinity chromatography technology	Ramachandran N (2004), Lleres D (2010)	2
MCM5	1	ORC6	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
ORC6	0	APP	1	pull down	Olah J (2011)	1
ORC5	0	CDC5L	2	pull down, affinity chromatography technology	Ramachandran N (2004), Lleres D (2010)	2
MCM7	5	ORC2	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
MCM4	3	MCM2	3	pull down, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), You Z (1999), Ishimi Y (1996), Tan BC (2006), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Drissi R (2015), Boldt K (2016)	11
MCM2	3	MCM6	5	two hybrid, pull down, pull down, two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Yabuta N (2003), Yabuta N (2003), Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), You Z (1999), You Z (2002), Havugimana PC (2012), Kristensen AR (2012), Rolland T (2014), Wan C (2015), Hein MY (2015), Drissi R (2015), Boldt K (2016)	15
ORC4	1	MCM2	3	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
RPA1	0	TERF2	2	affinity chromatography technology	Marechal A (2014)	1
DCTN6	0	ACTR10	0	affinity chromatography technology	Huttlin EL (2017)	1
RPA1	0	CDC5L	2	affinity chromatography technology, pull down, affinity chromatography technology	Marechal A (2014), Marechal A (2014), Lleres D (2010)	3
CDC5L	2	ORC6	0	affinity chromatography technology	Lleres D (2010)	1
MCM5	1	APP	1	pull down	Olah J (2011)	1
ORC2	0	MCM2	3	two hybrid, two hybrid, affinity chromatography technology, pull down	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Ramachandran N (2004)	4
ORC6	0	DCTN6	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MCM4	3	ORC4	1	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
DBF4	2	MCM6	5	enzymatic study	Masai H (2000)	1
CDC7	2	DBF4	2	two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Kneissl M (2003), Kumagai H (1999), Jiang W (1999), Jiang W (1999), Jiang W (1999), Kumagai H (1999), Kumagai H (1999), Liu P (2006), Masai H (2000), Masai H (2000), Huttlin EL (2017)	11
CDC5L	2	LRWD1	1	affinity chromatography technology	Lleres D (2010)	1
ORC2	0	DBF4	2	two hybrid, two hybrid, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003)	3
MCM4	3	ORC3	3	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
HMGA1	0	ORC6	0	pull down	Thomae AW (2008)	1
RPA1	0	MCM2	3	two hybrid, two hybrid, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Drissi R (2015)	3
HMGA1	0	ORC2	0	affinity chromatography technology	Thomae AW (2008)	1
MCM7	5	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
CDC45	1	MCM6	5	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
MCM6	5	MCM7	5	pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), Fujita M (1997), You Z (2002), Havugimana PC (2012), Ryu MJ (2006), Wan C (2015), Hein MY (2015), Boldt K (2016)	10
CDC5L	2	SFPQ	2	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Havugimana PC (2012), Wan C (2015), Lleres D (2010)	5
MCM2	3	APP	1	pull down	Olah J (2011)	1
CDC5L	2	MCM4	3	pull down	Ramachandran N (2004)	1
MCM2	3	SFPQ	2	affinity chromatography technology	Drissi R (2015)	1
ORC4	1	ORC6	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Sibani S (2005), Ramachandran N (2004)	5
MCM5	1	MCM7	5	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology	Kneissl M (2003), Fujita M (1997), DaFonseca CJ (2001), Havugimana PC (2012), Ramachandran N (2004), Wan C (2015), Lossaint G (2013)	7
HMGA1	0	TERF2	2	biochemical	Havugimana PC (2012)	1
XRCC6	3	ORC3	3	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
RPA1	0	ORC6	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
LRWD1	1	ORC2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Shen Z (2012), Shen Z (2012), Havugimana PC (2012), Vermeulen M (2010), Wan C (2015), Hein MY (2015), Hein MY (2015)	7
MCM6	5	ORC2	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
MCM7	5	DBF4	2	two hybrid, two hybrid, enzymatic study	Kneissl M (2003), Kneissl M (2003), Masai H (2000)	3
MCM6	5	ORC4	1	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
SNW1	0	SFPQ	2	affinity chromatography technology	Zhang C (2003)	1
CDC7	2	APP	1	pull down	Olah J (2011)	1
XRCC5	5	ORC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matheos D (2002), Sibani S (2005), Sibani S (2005)	3
ORC6	0	CDC6	0	pull down	Ramachandran N (2004)	1
RPA1	0	MCM4	3	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
SNW1	0	RPA1	0	affinity chromatography technology	Lleres D (2010)	1
ORC3	3	ORC5	0	two hybrid, two hybrid, biochemical, pull down, affinity chromatography technology, pull down, biochemical, pull down	Kneissl M (2003), Kneissl M (2003), Dhar SK (2001), Dhar SK (2001), Pinto S (1999), Vashee S (2001), Havugimana PC (2012), Ramachandran N (2004)	8
SNW1	0	ORC2	0	affinity chromatography technology	Lleres D (2010)	1
MCM4	3	MCM6	5	pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), Ishimi Y (1996), You Z (2002), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Boldt K (2016)	10
MCM5	1	ORC2	0	two hybrid, two hybrid, biochemical	Kneissl M (2003), Kneissl M (2003), Wan C (2015)	3
ORC3	3	APP	1	pull down	Olah J (2011)	1
ORC6	0	MCM2	3	pull down	Ramachandran N (2004)	1
MCM7	5	CDC7	2	two hybrid, two hybrid, enzymatic study	Kneissl M (2003), Kneissl M (2003), Masai H (2000)	3
CDC6	0	MCM7	5	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Fujita M (1999), Fujita M (1999), Sugimoto N (2015), Hubbi ME (2013)	7
ORC2	0	ORC5	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Quintana DG (1998), Dhar SK (2001), Dhar SK (2001), Vashee S (2001), Vashee S (2001), Keller C (2002), Havugimana PC (2012), Ramachandran N (2004), Vermeulen M (2010), Hein MY (2015)	13
ORC6	0	ACTR10	0	affinity chromatography technology	Huttlin EL (2015)	1
ORC6	0	CDC7	2	two hybrid, two hybrid, pull down	Kneissl M (2003), Kneissl M (2003), Ramachandran N (2004)	3
CDC45	1	ORC3	3	pull down	Ramachandran N (2004)	1
SPAG5	1	ORC6	0	two hybrid	Rolland T (2014)	1
ORC3	3	ORC4	1	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Dhar SK (2001), Pinto S (1999), Vashee S (2001), Sibani S (2005), Ramachandran N (2004)	5
ORC5	0	CDC7	2	pull down	Ramachandran N (2004)	1
RPA1	0	ORC2	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
MCM7	5	ORC5	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
CDC45	1	MCM7	5	two hybrid, two hybrid, pull down, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kukimoto I (1999), Liu P (2006)	4
ORC4	1	XRCC5	5	affinity chromatography technology, imaging technique	Sibani S (2005), Sibani S (2005)	2
DBF4	2	MCM4	3	two hybrid, enzymatic study	Kneissl M (2003), Masai H (2000)	2
TERF2	2	ORC2	0	pull down, affinity chromatography technology	Tatsumi Y (2008), Tatsumi Y (2008)	2
MCM7	5	ORC3	3	two hybrid, two hybrid, pull down	Kneissl M (2003), Kneissl M (2003), Ramachandran N (2004)	3
CDC6	0	MCM2	3	pull down, affinity chromatography technology	Ramachandran N (2004), Hubbi ME (2013)	2
MCM5	1	MCM2	3	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), DaFonseca CJ (2001), Havugimana PC (2012), Ramachandran N (2004), Wan C (2015), Drissi R (2015), Drissi R (2015), Huang J (2013), Lossaint G (2013)	10
LRWD1	1	ORC3	3	biochemical, affinity chromatography technology	Havugimana PC (2012), Hein MY (2015)	2
ORC2	0	ORC3	3	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Dhar SK (2001), Dhar SK (2001), Matsuoka S (2007), Pinto S (1999), Pinto S (1999), Vashee S (2001), Vashee S (2001), Sibani S (2005), Sibani S (2005), Keller C (2002), Havugimana PC (2012), Vermeulen M (2010), Wan C (2015), Hein MY (2015)	17
LRWD1	1	ORC4	1	affinity chromatography technology	Hein MY (2015)	1
MCM7	5	RPA1	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
TERF2	2	XRCC5	5	affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), Giannone RJ (2010)	2
CDC6	0	ORC2	0	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Mendez J (2000), Ramachandran N (2004)	5
XRCC5	5	ORC6	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Sibani S (2005), Sibani S (2005), Sibani S (2005)	3
ORC6	0	PPIL4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ORC6	0	CREB1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2