Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
EDNRA 1909 ENDOTHELIN CHEMBL437472 agonist GuideToPharmacologyInteractions
EDNRA 1909 SPARSENTAN CHEMBL539423 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, DrugBank
EDNRA 1909 PHENETHYLAMINE CHEMBL610 antagonist GuideToPharmacologyInteractions
EDNRA 1909 SITAXENTAN CHEMBL282724 antagonist TdgClinicalTrial, DrugBank, TTD 11704565, 11728166, 10961375, 11447307, 11752352, 11849873, 17472992
EDNRA 1909 NEBENTAN CHEMBL2107760 antagonist TdgClinicalTrial, ChemblInteractions
EDNRA 1909 SITAXENTAN SODIUM CHEMBL2105740 antagonist TTD
EDNRA 1909 ATRASENTAN HYDROCHLORIDE CHEMBL2106068 antagonist ChemblInteractions
EDNRA 1909 TEZOSENTAN CHEMBL61780 antagonist ChemblInteractions
EDNRA 1909 DL-PHENYLALANINE CHEMBL25080 agonist GuideToPharmacologyInteractions
EDNRA 1909 MACITENTAN CHEMBL2103873 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, DrugBank 24261583, 22862294, 22458347
EDNRA 1909 CEFADROXIL CHEMBL1644 antagonist GuideToPharmacologyInteractions
EDNRA 1909 ZIBOTENTAN CHEMBL1628688 antagonist, inhibitor TALC, TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, MyCancerGenomeClinicalTrial, TTD
EDNRA 1909 CHEMBL37860 CHEMBL37860 antagonist GuideToPharmacologyInteractions
EDNRA 1909 CHEMBL1232243 CHEMBL1232243 DrugBank 11093786
EDNRA 1909 PARATHION CHEMBL261919 agonist GuideToPharmacologyInteractions
EDNRA 1909 AMBRISENTAN CHEMBL1111 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND, DrugBank 19601701, 20811346, 19920913, 19389876
EDNRA 1909 ATRASENTAN CHEMBL9194 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TTD
EDNRA 1909 DARUSENTAN CHEMBL23261 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, DrugBank 17890870, 17049116
EDNRA 1909 PD-156707 CHEMBL8981 antagonist GuideToPharmacologyInteractions
EDNRA 1909 GUANFACINE CHEMBL862 antagonist GuideToPharmacologyInteractions
EDNRA 1909 BOSENTAN CHEMBL957 antagonist TdgClinicalTrial, ChemblInteractions, TEND, DrugBank, TTD 11704565, 11728166, 10961375, 11447307, 11752352, 11849873
EDNRA 1909 ENDOTHELIN 2 CHEMBL2304284 agonist GuideToPharmacologyInteractions
EDNRA 1909 SARAFOTOXIN S6B CHEMBL1222310 agonist GuideToPharmacologyInteractions
EDNRA 1909 AVOSENTAN CHEMBL2107803 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, DrugBank, TTD
EDNRA 1909 CHEMBL3188091 CHEMBL3188091 TdgClinicalTrial
EDNRA 1909 CLAZOSENTAN CHEMBL109648 antagonist TdgClinicalTrial, ChemblInteractions
EDNRA 1909 ENRASENTAN CHEMBL431651 antagonist ChemblInteractions
EDNRA 1909 ASPIRIN CHEMBL25 DrugBank 10727528

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
EDNRA rs5333 CC + CT prednisone efficacy yes Genotypes CC + CT is associated with increased resistance to prednisone in children with Nephrotic Syndrome as compared to genotype TT. 30672385 1450367980