Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
DPP4 1803 VILDAGLIPTIN CHEMBL142703 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, DrugBank, TTD 8100523, 15562200, 19149538
DPP4 1803 OMARIGLIPTIN CHEMBL2105762 inhibitor GuideToPharmacologyInteractions, ChemblInteractions
DPP4 1803 SITAGLIPTIN CHEMBL1422 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, TEND
DPP4 1803 CHEMBL383705 CHEMBL383705 DrugBank 17139284, 17016423, 10592235
DPP4 1803 CHEMBL381806 CHEMBL381806 DrugBank 10592235
DPP4 1803 CHEMBL1197118 CHEMBL1197118 DrugBank 10592235
DPP4 1803 ALOGLIPTIN BENZOATE CHEMBL227529 inhibitor ChemblInteractions
DPP4 1803 BEGELOMAB CHEMBL3833357 inhibitor, antibody GuideToPharmacologyInteractions, ChemblInteractions
DPP4 1803 CHEMBL1230015 CHEMBL1230015 DrugBank 10592235
DPP4 1803 CHEMBL1230044 CHEMBL1230044 DrugBank 10592235
DPP4 1803 CHEMBL374936 CHEMBL374936 DrugBank 10592235
DPP4 1803 CHEMBL452289 CHEMBL452289 DrugBank 10592235
DPP4 1803 CHEMBL63895 CHEMBL63895 DrugBank 10592235
DPP4 1803 CHEMBL225210 CHEMBL225210 DrugBank 10592235
DPP4 1803 CHEMBL1234200 CHEMBL1234200 DrugBank 10592235
DPP4 1803 CHEMBL564249 CHEMBL564249 DrugBank 10592235
DPP4 1803 CHEMBL237337 CHEMBL237337 DrugBank 10592235
DPP4 1803 ENALAPRIL CHEMBL578 NCI 16678199
DPP4 1803 CHEMBL1672127 CHEMBL1672127 inhibitor TTD
DPP4 1803 TRELAGLIPTIN SUCCINATE CHEMBL2105754 inhibitor ChemblInteractions
DPP4 1803 SITAGLIPTIN PHOSPHATE CHEMBL1201174 inhibitor ChemblInteractions
DPP4 1803 CARMEGLIPTIN CHEMBL591118 inhibitor ChemblInteractions
DPP4 1803 ALOGLIPTIN CHEMBL376359 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, DrugBank, TTD
DPP4 1803 CHEMBL34062 CHEMBL34062 DrugBank 17139284, 17016423, 10592235
DPP4 1803 CHEMBL233360 CHEMBL233360 DrugBank 10592235
DPP4 1803 CHEMBL250787 CHEMBL250787 DrugBank 10592235
DPP4 1803 CHEMBL385711 CHEMBL385711 DrugBank 10592235
DPP4 1803 CHEMBL272114 CHEMBL272114 DrugBank 10592235
DPP4 1803 CHEMBL217271 CHEMBL217271 DrugBank 10592235
DPP4 1803 CHEMBL257036 CHEMBL257036 DrugBank 10592235
DPP4 1803 CHEMBL1232261 CHEMBL1232261 DrugBank 10592235
DPP4 1803 CHEMBL425584 CHEMBL425584 DrugBank 10592235
DPP4 1803 GOSOGLIPTIN CHEMBL515387 inhibitor ChemblInteractions, DrugBank 10592235
DPP4 1803 CHEMBL227954 CHEMBL227954 DrugBank 10592235
DPP4 1803 CHEMBL77538 CHEMBL77538 inhibitor TTD
DPP4 1803 SAXAGLIPTIN HYDROCHLORIDE CHEMBL1201743 inhibitor ChemblInteractions
DPP4 1803 DESERPIDINE CHEMBL1200515 inhibitor GuideToPharmacologyInteractions
DPP4 1803 LINAGLIPTIN CHEMBL237500 inhibitor GuideToPharmacologyInteractions, ChemblInteractions, DrugBank, TTD 22149370
DPP4 1803 SAXAGLIPTIN CHEMBL385517 inhibitor TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, DrugBank, TTD 10592235, 16033281
DPP4 1803 CHEMBL525028 CHEMBL525028 DrugBank 10592235
DPP4 1803 CHEMBL382127 CHEMBL382127 DrugBank 10592235
DPP4 1803 CHEMBL1230763 CHEMBL1230763 DrugBank 10592235
DPP4 1803 CHEMBL237786 CHEMBL237786 DrugBank 10592235
DPP4 1803 CHEMBL235134 CHEMBL235134 DrugBank 10592235
DPP4 1803 CHEMBL218289 CHEMBL218289 DrugBank 10592235
DPP4 1803 CHEMBL386369 CHEMBL386369 inhibitor TTD
DPP4 1803 DENAGLIPTIN CHEMBL2110666 inhibitor TTD
DPP4 1803 CAPTOPRIL CHEMBL1560 NCI 17531305

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
DPP4 rs17848916 AC peginterferon alfa-2a efficacy no PEG-interferon alfa (2a and b) was co-adminstered with ribavirin. Response was assessed by sustained virological response (SVR) percent by genotype. Please note, alleles have been complemented to the + chromosomal strand. Genotype AC is not associated with response to peginterferon alfa-2a or peginterferon alfa-2b in people with Hepatitis C, Chronic as compared to genotype AA. 26339796 1446904218
DPP4 rs17574 AA peginterferon alfa-2a efficacy no PEG-interferon alfa (2a and b) was co-adminstered with ribavirin. Response was assessed by sustained virological response (SVR) percent by genotype. Please note, alleles have been complemented to the + chromosomal strand. Genotype AA is not associated with response to peginterferon alfa-2a or peginterferon alfa-2b in people with Hepatitis C, Chronic as compared to genotype AG. 26339796 1446904224
DPP4 rs13015258 GG peginterferon alfa-2a efficacy no PEG-interferon alfa (2a and b) was co-adminstered with ribavirin. Response was assessed by sustained virological response (SVR) percent by genotype. Please note, alleles have been complemented to the + chromosomal strand. Genotype GG is not associated with response to peginterferon alfa-2a or peginterferon alfa-2b in people with Hepatitis C, Chronic as compared to genotypes GT + TT. 26339796 1446904209