PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
KDM6A	8	KMT2C	28	affinity chromatography technology	Lee MG (2007)	1
BRD4	8	HIST2H3C	0	pull down	Liu Y (2008)	1
RBBP5	3	KMT2C	28	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Goo YH (2003), Goo YH (2003), Cho YW (2007), Shinsky SA (2015), Alicea-Velazquez NL (2016)	5
HIST2H3C	0	CDCA8	0	pull down	Yamagishi Y (2010)	1
PKN1	4	HIST2H3C	0	enzymatic study	Metzger E (2008)	1
YWHAQ	0	CHAF1A	1	pull down	Hoek M (2011)	1
KDM6A	8	KMT2D	30	affinity chromatography technology, affinity chromatography technology	Lee MG (2007), Kim JH (2014)	2
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
MECP2	36	TAF1B	0	affinity chromatography technology	Huttlin EL (2017)	1
SMC2	3	HIST2H3C	0	affinity chromatography technology	Tada K (2011)	1
PRMT6	2	HIST2H3C	0	enzymatic study, enzymatic study	Hyllus D (2007), Cloutier P (2013)	2
KDM1A	2	HIST2H3C	0	x-ray crystallography, enzymatic study	Lan F (2007), Shi Y (2004)	2
HDGFL2	3	HIST2H3C	0	unspecified method, x-ray crystallography	Wu H (2011), Wu H (2011)	2
ING1	2	HIST2H3C	0	unspecified method, x-ray crystallography	Pena PV (2008), Pena PV (2008)	2
PCNA	0	UHRF1	3	affinity chromatography technology	Hein MY (2015)	1
KDM1A	2	MTA1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Wang Y (2009), Wang Y (2009), Cui S (2011), Cui S (2011)	4
BAG6	2	HIST2H3C	0	affinity chromatography technology, affinity chromatography technology	Wakeman TP (2012), Wakeman TP (2012)	2
OBSL1	9	YWHAQ	0	affinity chromatography technology	Hanson D (2014)	1
MCM2	3	YWHAQ	0	affinity chromatography technology	Drissi R (2015)	1
ING1	2	PCNA	0	biochemical, affinity chromatography technology, affinity chromatography technology	Scott M (2001), Scott M (2001), Simpson F (2006)	3
PHF21A	4	HIST2H3C	0	pull down, x-ray crystallography	Lan F (2007), Lan F (2007)	2
NRDC	3	TBL1X	1	affinity chromatography technology	Li J (2012)	1
DDB2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
IFNGR1	0	STAT1	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Pang Q (2000), Pang Q (2000), Noon-Song EN (2011)	3
RERE	9	KAT6A	19	two hybrid	Lim J (2006)	1
AURKB	2	INCENP	4	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Gassmann R (2004), Xu Z (2009), Xu Z (2009), Katayama H (2008), Kaitna S (2000), Maerki S (2009), Vader G (2006), Honda R (2003), Ban R (2011), Sun L (2008), Nozawa RS (2010), Jeyaprakash AA (2007), Klein UR (2006), Klein UR (2006), Fu J (2009), Fu J (2009), Li X (2004), Gomez V (2010)	18
BRD4	8	EP300	36	affinity chromatography technology, affinity chromatography technology, genetic interference	Reynoird N (2010), Wong MM (2014), Wong AS (2016)	3
H2AFX	1	HIST2H3C	0	affinity chromatography technology	Dittmann K (2011)	1
OBSL1	9	MCM2	3	affinity chromatography technology	Hanson D (2014)	1
H2AFX	1	BRD1	5	pull down	Lee HS (2010)	1
FN1	17	RPS6KA5	2	two hybrid	Wang J (2011)	1
EHMT2	4	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Oh ST (2014), Oh ST (2014)	2
HIST2H3C	0	XIST	0	imaging technique	Ganesan S (2002)	1
BAG6	2	DOT1L	7	affinity chromatography technology, affinity chromatography technology	Wakeman TP (2012), Wakeman TP (2012)	2
EHMT2	4	CDK8	1	affinity chromatography technology	Ding N (2008)	1
HIST2H3C	0	PHF2	6	affinity chromatography technology	Li J (2012)	1
IGSF8	1	HIST2H3C	0	affinity chromatography technology	Perez-Hernandez D (2013)	1
ELP3	5	PCNA	0	affinity chromatography technology	Li Q (2009)	1
KDM1A	2	NSD2	9	affinity chromatography technology	Marango J (2008)	1
MCM2	3	H2AFX	1	affinity chromatography technology, affinity chromatography technology	Drissi R (2015), Huttlin EL (2017)	2
BRCA1	7	KDM1A	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Woods NT (2012), Ertych N (2016)	3
BRCA1	7	BRD4	8	genetic interference	Shen JP (2017)	1
KDM6A	8	HIST2H3C	0	enzymatic study	Kristensen JB (2011)	1
SMYD2	0	HIST2H3C	0	enzymatic study	Wu J (2011)	1
CDCA8	0	INCENP	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Gassmann R (2004), Gassmann R (2004), Xu Z (2009), Vader G (2006), Knauer SK (2006), Jeyaprakash AA (2007), Jeyaprakash AA (2007), Jeyaprakash AA (2007), Klein UR (2006), Klein UR (2006), Klein UR (2006), Klein UR (2006), Klein UR (2009)	13
KAT6A	19	KMT2A	58	affinity chromatography technology, affinity chromatography technology, imaging technique	Paggetti J (2010), Paggetti J (2010), Largeot A (2013)	3
YWHAQ	0	ING1	2	pull down	Gong W (2006)	1
DOT1L	7	HIST2H3C	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Wu L (2011), Wakeman TP (2012), Wakeman TP (2012)	3
BRCA1	7	XIST	0	imaging technique, imaging technique	Ganesan S (2004), Ganesan S (2002)	2
CHAF1B	2	PCNA	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
BRD4	8	NSD2	9	affinity chromatography technology	Rahman S (2011)	1
H2AFX	1	KAT2B	2	affinity chromatography technology	Lee HS (2010)	1
BRCA1	7	H2AFX	1	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, enzymatic study, affinity chromatography technology, imaging technique	Mallery DL (2002), Paull TT (2000), Ray A (2009), Tsai WB (2008), Mok MT (2010), Nelson AC (2010), Chen A (2002), Dutta D (2015), Dutta D (2015)	9
SETD1B	15	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007), Lee JH (2010), Hein MY (2015), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016)	7
KDM6A	8	NCOA6	6	affinity chromatography technology, affinity chromatography technology	Lee MG (2007), Lee J (2008)	2
YWHAQ	0	HIST2H3C	0	affinity chromatography technology	Winter S (2008)	1
SMARCA4	19	HIST2H3C	0	unspecified method	Shen W (2007)	1
CXXC1	3	KMT2D	30	affinity chromatography technology, affinity chromatography technology	Ansari KI (2008), Ansari KI (2008)	2
NANOG	0	MCM2	3	affinity chromatography technology	Oliviero G (2015)	1
EP300	36	HIST2H3C	0	enzymatic study	Cereseto A (2005)	1
MECP2	36	HIRA	5	affinity chromatography technology	Huttlin EL (2017)	1
CXXC1	3	HIST2H3C	0	affinity chromatography technology	Ansari KI (2008)	1
HIST2H3C	0	INCENP	4	pull down	Yamagishi Y (2010)	1
NANOG	0	TBL1X	1	affinity chromatography technology	Oliviero G (2015)	1
SETD1A	12	SETD1B	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007)	3
SMARCA4	19	STAT1	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Ni Z (2005), Cheng MB (2010), Zhang Y (2010)	3
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
ING4	1	KMT2A	58	affinity chromatography technology	Hein MY (2015)	1
RERE	9	EP300	36	affinity chromatography technology	Shen Y (2007)	1
HIST2H3C	0	KAT5	1	affinity chromatography technology, enzymatic study	Jeong KW (2011), Koiwai K (2011)	2
RNF20	9	HIST2H3C	0	enzymatic study	Kim J (2011)	1
EP300	36	TAF1B	0	two hybrid	Shikama N (2000)	1
CHAF1A	1	PCNA	0	pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Moggs JG (2000), Rolef Ben-Shahar T (2009), Gerard A (2006), Gerard A (2006), Gerard A (2006), Naryzhny SN (2005), Sarraf SA (2004), Hoek M (2011), Hoek M (2011), Takami Y (2007), Hein MY (2015)	11
CDK8	1	BAG6	2	affinity chromatography technology	Hein MY (2015)	1
NANOG	0	ELP3	5	affinity chromatography technology	Oliviero G (2015)	1
EP300	36	MCM2	3	pull down	Karmakar S (2010)	1
TAF1B	0	HIST2H3C	0	affinity chromatography technology	Kato K (2006)	1
KAT6A	19	EP300	36	affinity chromatography technology	Rokudai S (2009)	1
ING4	1	HIST2H3C	0	x-ray crystallography	Palacios A (2008)	1
PKN1	4	RBBP5	3	imaging technique	Kim JY (2014)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
KAT2A	1	HIST2H3C	0	enzymatic study	Cereseto A (2005)	1
PKN1	4	KMT2A	58	imaging technique	Kim JY (2014)	1
IFNGR1	0	JAK2	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Kotenko SV (1995), Noon-Song EN (2011), Noon-Song EN (2011)	3
HIST2H3C	0	KAT6A	19	pull down	Paggetti J (2010)	1
ATRX	7	H2AFX	1	imaging technique	Choi EH (2017)	1
FN1	17	PCNA	0	affinity chromatography technology	Humphries JD (2009)	1
ITGA4	4	MCM2	3	affinity chromatography technology	Byron A (2012)	1
KDM3A	11	HIST2H3C	0	enzymatic study	Yamane K (2006)	1
KMT2B	22	HIST2H3C	0	enzymatic study	Zhang P (2012)	1
HIST2H3C	0	MTA1	3	affinity chromatography technology	Li J (2012)	1
FN1	17	YWHAQ	0	affinity chromatography technology	Humphries JD (2009)	1
OBSL1	9	KDM1A	2	affinity chromatography technology	Hanson D (2014)	1
BRD4	8	KDM3A	11	genetic interference	Wong AS (2016)	1
DOT1L	7	STAT1	1	affinity chromatography technology, pull down	Shah S (2011), Shah S (2011)	2
ING1	2	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuzmichev A (2002), Kuzmichev A (2002), Kuzmichev A (2002)	3
BAG6	2	MTA1	3	affinity chromatography technology	Hein MY (2015)	1
KAT2A	1	WDHD1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li Y (2011), Li Y (2011), Li Y (2012), Li Y (2012)	4
SMARCA4	19	KDM6A	8	affinity chromatography technology	Lee S (2012)	1
CXXC1	3	SETD1B	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Butler JS (2008), Lee JH (2007), Lee JH (2007), Lee JH (2007), Havugimana PC (2012), Tang Z (2013), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016)	11
EHMT2	4	HIST2H3C	0	enzymatic study, enzymatic study, enzymatic study	Yu Y (2012), Islam K (2011), Nishio H (2004)	3
BRCA1	7	CDK8	1	biochemical	Scully R (1997)	1
HIRA	5	HIST2H3C	0	affinity chromatography technology	Kang B (2011)	1
RPS6KA5	2	EP300	36	affinity chromatography technology	Janknecht R (2003)	1
OBSL1	9	PCNA	0	affinity chromatography technology	Hanson D (2014)	1
YWHAQ	0	RNF20	9	affinity chromatography technology	Ichimura T (2013)	1
VCAM1	2	HIST2H3C	0	affinity chromatography technology	Humphries JD (2009)	1
BRD4	8	KDM4C	2	genetic interference, genetic interference	Wong AS (2016), Wong AS (2016)	2
ING4	1	JADE1	6	affinity chromatography technology, pull down, affinity chromatography technology	Doyon Y (2006), Avvakumov N (2012), Hein MY (2015)	3
OBSL1	9	UHRF1	3	affinity chromatography technology	Hanson D (2014)	1
KMT2D	30	HIST2H3C	0	enzymatic study	Zhang P (2012)	1
RPS6KA5	2	SMARCA4	19	affinity chromatography technology	Drobic B (2010)	1
FN1	17	BAG6	2	affinity chromatography technology	Humphries JD (2009)	1
NANOG	0	ING1	2	affinity chromatography technology	Oliviero G (2015)	1
DDB2	1	HIST2H3C	0	enzymatic study	Lan L (2012)	1
NASP	3	HIST2H3C	0	two hybrid	Rual JF (2005)	1
FN1	17	MCM2	3	affinity chromatography technology	Humphries JD (2009)	1
CUL7	4	BAG6	2	affinity chromatography technology	Hanson D (2014)	1
CXXC1	3	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013), Tang Z (2013)	3
KDM4C	2	HIST2H3C	0	enzymatic study	Kristensen JB (2011)	1
NANOG	0	MTA1	3	affinity chromatography technology	Oliviero G (2015)	1
KMT2C	28	HIST2H3C	0	pull down, enzymatic study	Goo YH (2003), Zhang P (2012)	2
ING1	2	KAT2B	2	affinity chromatography technology	Vieyra D (2002)	1
RPS6KA5	2	HIST2H3C	0	enzymatic study	Zhang Y (2004)	1
EP300	36	PCNA	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hasan S (2001), Hasan S (2001), Hasan S (2001), Hong R (2003), Hong R (2003), Cazzalini O (2008), Cazzalini O (2008), Naryzhny SN (2004), Cazzalini O (2014), Cazzalini O (2014)	10
EP300	36	SETD1A	12	pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013)	2
FN1	17	ITGA4	4	affinity chromatography technology	Humphries JD (2009)	1
ELP3	5	HIST2H3C	0	enzymatic study	Kim JH (2002)	1
POU5F1	0	HIST2H3C	0	affinity chromatography technology	Oliviero G (2015)	1
VCAM1	2	BAG6	2	affinity chromatography technology	Braunstein I (2015)	1
CD81	0	PKN1	4	affinity chromatography technology	Perez-Hernandez D (2013)	1
VCAM1	2	MCM2	3	affinity chromatography technology	Humphries JD (2009)	1
ING4	1	BRPF1	8	affinity chromatography technology	Hein MY (2015)	1
CXXC1	3	KMT2A	58	affinity chromatography technology, affinity chromatography technology	Ansari KI (2008), Ansari KI (2008)	2
BRCA1	7	MCM2	3	affinity chromatography technology	Ertych N (2016)	1
CHUK	5	HIST2H3C	0	affinity chromatography technology, pull down	Zhu F (2007), Zhu F (2007)	2
EP300	36	NANOG	0	affinity chromatography technology	Xie X (2014)	1
CDK8	1	HIST2H3C	0	enzymatic study	Rovnak J (2012)	1
VRK1	0	HIST2H3C	0	pull down, enzymatic study	Kang TH (2007), Kang TH (2007)	2
ITGA4	4	PDHA1	7	affinity chromatography technology	Byron A (2012)	1
KAT5	1	PCNA	0	affinity chromatography technology	Du Z (2010)	1
RBBP5	3	KMT2A	58	affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, pull down	Yokoyama A (2004), Yokoyama A (2004), Yokoyama A (2004), Blobel GA (2009), Dou Y (2005), Dharmarajan V (2012), Hu D (2013), Tang Z (2013), Alicea-Velazquez NL (2016), Weirich S (2017), Weirich S (2017)	11
H2AFX	1	KAT2A	1	affinity chromatography technology	Lee HS (2010)	1
OBSL1	9	SMARCA4	19	affinity chromatography technology	Hanson D (2014)	1
EHMT2	4	POU5F1	0	affinity chromatography technology	Hawkins PG (2010)	1
BRCA1	7	HIST2H3C	0	imaging technique	Ganesan S (2002)	1
H2AFX	1	KAT5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Heo K (2008), Heo K (2008), Heo K (2008), Lee HS (2010)	4
HIST2H3C	0	STAT1	1	affinity chromatography technology	Noon-Song EN (2011)	1
CHAF1B	2	HIST2H3C	0	affinity chromatography technology	Kang B (2011)	1
EP300	36	NAP1L4	3	two hybrid, affinity chromatography technology, pull down	Shikama N (2000), Shikama N (2000), Shikama N (2000)	3
BRD1	5	HIST2H3C	0	unspecified method	Wu H (2011)	1
H2AFX	1	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
HIST2H3C	0	SNCA	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Kontopoulos E (2006), Kontopoulos E (2006), Kontopoulos E (2006)	3
CD81	0	IGSF8	1	affinity chromatography technology	Clark KL (2001)	1
EP300	36	ING1	2	affinity chromatography technology	Vieyra D (2002)	1
NCOA6	6	KMT2B	22	affinity chromatography technology, affinity chromatography technology	Lee J (2008), Lee S (2006)	2
BRD1	5	NAP1L4	3	affinity chromatography technology	Fryland T (2016)	1
KMT2A	58	DOT1L	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Monroe SC (2011), Tan J (2011), Tan J (2011)	3
DNMT3L	2	HIST2H3C	0	pull down	Ooi SK (2007)	1
CDK8	1	SMARCA4	19	pull down, pull down	Fukasawa R (2012), Fukasawa R (2012)	2
HIST2H3C	0	NRDC	3	affinity chromatography technology, pull down	Li J (2012), Li J (2012)	2
HIST2H3C	0	BIRC5	1	pull down, pull down	Yamagishi Y (2010), Yamagishi Y (2010)	2
BIRC5	1	AURKB	2	two hybrid, pull down, genetic interference, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wheatley SP (2001), Chen J (2003), Chen J (2003), Wheatley SP (2001), Xu Z (2009), Maerki S (2009), Knauer SK (2006), Knauer SK (2006), Ban R (2011), Sun L (2008), Noton EA (2006), Noton EA (2006), Fu J (2009), Gomez V (2010)	14
HIST2H3C	0	IFNGR1	0	affinity chromatography technology	Noon-Song EN (2011)	1
RERE	9	HIST2H3C	0	enzymatic study	Wang L (2008)	1
BRD4	8	SMARCA4	19	affinity chromatography technology	Rahman S (2011)	1
HIRA	5	EP300	36	imaging technique	Pchelintsev NA (2013)	1
SETD1A	12	HIST2H3C	0	enzymatic study	Zhang P (2012)	1
CUL7	4	PCNA	0	affinity chromatography technology	Hanson D (2014)	1
KAT2B	2	HIST2H3C	0	enzymatic study, enzymatic study	Ghizzoni M (2012), Kim JH (2002)	2
AURKB	2	HIST2H3C	0	enzymatic study, pull down	Wang F (2011), Yamagishi Y (2010)	2
MSL2	3	HIST2H3C	0	enzymatic study	Wu L (2011)	1
BRCA1	7	RBBP5	3	affinity chromatography technology	Ertych N (2016)	1
PCNA	0	NSD2	9	affinity chromatography technology, pull down	Evans DL (2016), Evans DL (2016)	2
WDHD1	4	HIST2H3C	0	affinity chromatography technology	Li Y (2012)	1
KAT6A	19	BRPF1	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rokudai S (2009), Rokudai S (2009), Ullah M (2008), Ullah M (2008), Laue K (2008)	5
MECP2	36	HIST2H3C	0	x-ray crystallography	Yang C (2011)	1
EP300	36	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Paulson M (1999), Hiroi M (2003), Ray S (2002), Strassheim D (2009), Liu X (2008), Ghosh AK (2001), Yang WS (2005), Zhang Y (2015), Kotla S (2015), Kotla S (2015)	10
ING4	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Shiseki M (2003), Shiseki M (2003)	2
POU5F1	0	ELP3	5	affinity chromatography technology	Oliviero G (2015)	1
KMT2A	58	HIST2H3C	0	enzymatic study	Wu L (2011)	1
RNF4	1	HIST2H3C	0	enzymatic study	Groocock LM (2014)	1
NANOG	0	RBBP5	3	affinity chromatography technology	Oliviero G (2015)	1
PCNA	0	RNF20	9	affinity chromatography technology	Hein MY (2015)	1
RNF4	1	MECP2	36	enzymatic study	Wang Y (2014)	1
CD81	0	ITGA4	4	affinity chromatography technology	Serru V (1999)	1
VCAM1	2	ITGA4	4	affinity chromatography technology, affinity chromatography technology	Humphries JD (2009), Byron A (2012)	2
MCM2	3	HIST2H3C	0	affinity chromatography technology	Drissi R (2015)	1
DNMT3L	2	MECP2	36	pull down	Pacaud R (2014)	1
PIM1	2	HIST2H3C	0	enzymatic study	Zippo A (2007)	1
CUL7	4	AURKB	2	affinity chromatography technology	Hanson D (2014)	1
H2AFX	1	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, pull down	Park JH (2006), Lee HS (2010), Lee HS (2010)	3
MUM1	1	HIST2H3C	0	unspecified method	Wu H (2011)	1
CDCA8	0	AURKB	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Sampath SC (2004), Gassmann R (2004), Gassmann R (2004), Xu Z (2009), Knauer SK (2006), Ban R (2011), Jeyaprakash AA (2007), Jelluma N (2008), Gomez V (2010), Gomez V (2010), Klein UR (2009)	11
RNF4	1	UHRF1	3	affinity chromatography technology	Bruderer R (2011)	1
BRCA1	7	TAF1B	0	affinity chromatography technology	Johnston R (2016)	1
BRCA1	7	SETD1A	12	affinity chromatography technology	Ertych N (2016)	1
CUL7	4	YWHAQ	0	affinity chromatography technology	Hanson D (2014)	1
NCOA6	6	HIST2H3C	0	pull down, affinity chromatography technology	Goo YH (2003), Goo YH (2003)	2
ATRX	7	HIST2H3C	0	unspecified method, x-ray crystallography, x-ray crystallography, unspecified method	Iwase S (2011), Iwase S (2011), Eustermann S (2011), Eustermann S (2011)	4
JAK2	1	STAT1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Cheng MB (2010), Cheng MB (2010), Manea A (2010), Andl CD (2004), Chang YJ (2004)	5
CXXC1	3	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Lee JH (2005), Lee JH (2005), Lee JH (2005), Ansari KI (2008), Butler JS (2008), Mak AB (2010), Kim J (2009), Tang Z (2013), Hein MY (2015), Huttlin EL (2017)	11
NCOA6	6	EP300	36	affinity chromatography technology, pull down	Ko L (2000), Ko L (2000)	2
MTA1	3	EP300	36	affinity chromatography technology	Gururaj AE (2006)	1
EP300	36	CHUK	5	imaging technique	Hao L (2010)	1
UHRF1	3	KAT5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Achour M (2009), Du Z (2010), Dai C (2013), Dai C (2013), Dai C (2013)	5
ARID4A	3	HIST2H3C	0	pull down	Gong W (2012)	1
BAG6	2	WDHD1	4	biochemical	Kristensen AR (2012)	1
SETD1A	12	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2005), Lee JH (2007), Lee JH (2007), Lee JH (2008), Lee JH (2010), Mersman DP (2012), Mak AB (2010), Li X (2011), Havugimana PC (2012), Kim J (2013), Tang Z (2013), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016)	13
JADE1	6	KAT5	1	affinity chromatography technology	Panchenko MV (2004)	1
EP300	36	KAT5	1	affinity chromatography technology, affinity chromatography technology	Col E (2005), Col E (2005)	2
CDCA8	0	BIRC5	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sampath SC (2004), Gassmann R (2004), Gassmann R (2004), Knauer SK (2006), Knauer SK (2006), Knauer SK (2006), Jeyaprakash AA (2007), Jeyaprakash AA (2007), Jeyaprakash AA (2007), Klein UR (2006), Klein UR (2006), Noton EA (2006), Noton EA (2006), Jelluma N (2008), Gomez V (2010), Klein UR (2009), Huttlin EL (2015), Huttlin EL (2017)	18
FN1	17	HIST2H3C	0	affinity chromatography technology	Humphries JD (2009)	1
KDM6A	8	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee MG (2007), Cho YW (2007), De Santa F (2007)	3
BRD4	8	PHF2	6	genetic interference, genetic interference	Wong AS (2016), Wong AS (2016)	2
RBBP5	3	HIST2H3C	0	pull down	Goo YH (2003)	1
CXXC1	3	SETD1A	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ansari KI (2008), Ansari KI (2008), Tate CM (2009), Lee JH (2005), Lee JH (2005), Lee JH (2005), Butler JS (2008), Lee JH (2007), Lee JH (2007), Tate CM (2010), Lee JH (2008), Kim J (2009), Kim J (2013), Tang Z (2013), Tang Z (2013), Hein MY (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016)	18
OBSL1	9	CDCA8	0	affinity chromatography technology	Hanson D (2014)	1
EP300	36	RBBP5	3	affinity chromatography technology	Tang Z (2013)	1
HIST2H3C	0	JAK2	1	affinity chromatography technology	Noon-Song EN (2011)	1
BRPF1	8	HIST2H3C	0	unspecified method, x-ray crystallography	Wu H (2011), Wu H (2011)	2
HIRA	5	SMARCA4	19	imaging technique, affinity chromatography technology, affinity chromatography technology	Pchelintsev NA (2013), Pchelintsev NA (2013), Pchelintsev NA (2013)	3
AURKB	2	EP300	36	affinity chromatography technology	Fogeron ML (2013)	1
HIST2H3C	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Yu Y (2012), Yu Y (2012), Yu Y (2012)	3
BRD7	2	SMARCA4	19	affinity chromatography technology	Kaeser MD (2008)	1
BRD4	8	KDM6A	8	genetic interference	Wong AS (2016)	1
TAF1B	0	KAT2B	2	imaging technique	Shen M (2013)	1
JADE1	6	HIST2H3C	0	pull down	Saksouk N (2009)	1
PARP3	0	HIST2H3C	0	affinity chromatography technology	Ewing RM (2007)	1
CDK8	1	KAT2B	2	affinity chromatography technology	Cho H (1998)	1
YWHAQ	0	H2AFX	1	affinity chromatography technology	Pozuelo-Rubio M (2010)	1
RNF20	9	MSL2	3	biochemical, biochemical	Wu L (2014), Wu L (2014)	2
PDHA1	7	HIST2H3C	0	affinity chromatography technology	Malty RH (2017)	1
CD81	0	HIST2H3C	0	affinity chromatography technology	Perez-Hernandez D (2013)	1
NCOA6	6	RBBP5	3	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goo YH (2003), Goo YH (2003), Goo YH (2003), Lee J (2008), Patel SR (2007), Patel SR (2007), Cho YW (2007), Cho YW (2007), Tang Z (2013)	9
EP300	36	BAG6	2	affinity chromatography technology	Jiang W (2011)	1
NANOG	0	DOT1L	7	genetic interference	Onder TT (2012)	1
CUL7	4	HIST2H3C	0	affinity chromatography technology	Hanson D (2014)	1
BRD4	8	KMT2A	58	genetic interference	Wong AS (2016)	1
OBSL1	9	HIST2H3C	0	affinity chromatography technology	Hanson D (2014)	1
BRCA1	7	YWHAQ	0	affinity chromatography technology	Ertych N (2016)	1
ING4	1	BRD1	5	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Fryland T (2016)	2
YWHAQ	0	SNCA	0	affinity chromatography technology	Watabe M (2004)	1
CHAF1A	1	HIST2H3C	0	affinity chromatography technology	Kang B (2011)	1
NCOA6	6	KMT2C	28	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goo YH (2003), Goo YH (2003), Goo YH (2003), Lee J (2008), Lee S (2006)	5
EHMT2	4	UHRF1	3	imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin W (2010), Kim JK (2009), Kim JK (2009), Zhang J (2011)	4
BRD7	2	EP300	36	affinity chromatography technology	Drost J (2010)	1
SETD1B	15	HIST2H3C	0	enzymatic study	Zhang P (2012)	1
PHF21A	4	KDM1A	2	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2002), Iwase S (2004), Hakimi MA (2003), Shi YJ (2005), Lee MG (2005), Boldt K (2016)	6
BIRC5	1	H2AFX	1	affinity chromatography technology	Capalbo G (2010)	1
KDM2A	4	HIST2H3C	0	enzymatic study	Xu W (2011)	1
ICAM1	6	HIST2H3C	0	affinity chromatography technology	Perez-Hernandez D (2013)	1
CHAF1B	2	CHAF1A	1	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Marheineke K (1998), Kang B (2011), Havugimana PC (2012), Wan C (2015), Hauri S (2016)	5
ITGA4	4	HIST2H3C	0	affinity chromatography technology	Byron A (2012)	1
HIST2H3C	0	UHRF1	3	affinity chromatography technology, x-ray crystallography, x-ray crystallography, unspecified method, unspecified method	Li J (2012), Arita K (2012), Nady N (2011), Nady N (2011), Rothbart SB (2012)	5
KAT5	1	BRCA1	7	two hybrid	Hill SJ (2014)	1
RERE	9	EHMT2	4	affinity chromatography technology, pull down	Wang L (2008), Wang L (2008)	2
OBSL1	9	CUL7	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Litterman N (2011), Litterman N (2011), Hanson D (2011), Hanson D (2011), Nie J (2015)	5
HIST2H3C	0	BRD7	2	affinity chromatography technology, affinity chromatography technology, unspecified method	Peng C (2006), Peng C (2006), Peng C (2006)	3
KDM1A	2	EP300	36	affinity chromatography technology	Garcia-Bassets I (2007)	1
BIRC5	1	INCENP	4	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Wheatley SP (2001), Wheatley SP (2001), Xu Z (2009), Vader G (2006), Knauer SK (2006), Knauer SK (2006), Jeyaprakash AA (2007), Klein UR (2006), Klein UR (2006), Klein UR (2006), Huttlin EL (2017)	11
NSD2	9	HIST2H3C	0	unspecified method	Wu H (2011)	1
NANOG	0	HIST2H3C	0	affinity chromatography technology	Oliviero G (2015)	1
RBBP5	3	KMT2D	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Wysocka J (2005), Patel SR (2007), Mo R (2006), Mo R (2006), Kim JH (2014), Hu D (2013), Alicea-Velazquez NL (2016)	7
OBSL1	9	CHAF1B	2	affinity chromatography technology	Hanson D (2014)	1
POU5F1	0	BAG6	2	affinity chromatography technology	Oliviero G (2015)	1
BRCA1	7	BRD7	2	two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Harte MT (2010), Harte MT (2010), Harte MT (2010), Harte MT (2010)	4
NAP1L4	3	HIST2H3C	0	pull down	Shikama N (2000)	1
TBL1X	1	HIST2H3C	0	pull down	Yoon HG (2003)	1
KMT2B	22	RBBP5	3	affinity chromatography technology, affinity chromatography technology, pull down	Cho YW (2007), Shi L (2011), Alicea-Velazquez NL (2016)	3
BRCA1	7	STAT1	1	affinity chromatography technology, pull down, two hybrid	Ouchi T (2000), Ouchi T (2000), Ouchi T (2000)	3
BRCA1	7	SMARCA4	19	affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Hill DA (2004), Bochar DA (2000), Bochar DA (2000), Bochar DA (2000), Tu Z (2013), Ertych N (2016)	6
BRCA1	7	JAK2	1	affinity chromatography technology	Gao B (2001)	1