Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CHRM1 1128 METHIXENE CHEMBL1201342 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 PIRENZEPINE CHEMBL9967 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, DrugBank, TTD 11752352, 12717096
CHRM1 1128 TROPICAMIDE CHEMBL1200604 antagonist DrugBank 17594079
CHRM1 1128 LEVOMEPROMAZINE CHEMBL1764 antagonist TdgClinicalTrial, TEND, DrugBank 2870716, 2899826
CHRM1 1128 ARECOLINE CHEMBL7303 agonist GuideToPharmacologyInteractions, DrugBank 17139284, 17016423
CHRM1 1128 N-DESMETHYLCLOZAPINE CHEMBL845 allosteric modulator TdgClinicalTrial, GuideToPharmacologyInteractions, DrugBank
CHRM1 1128 ACLIDINIUM CHEMBL1194325 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, DrugBank
CHRM1 1128 BETHANECHOL CHEMBL1482 agonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND
CHRM1 1128 CHEMBL74300 CHEMBL74300 agonist GuideToPharmacologyInteractions
CHRM1 1128 MILAMELINE CHEMBL151938 agonist GuideToPharmacologyInteractions
CHRM1 1128 BRUCINE CHEMBL501756 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL343357 CHEMBL343357 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL608112 CHEMBL608112 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 ESTAZOLAM CHEMBL285674 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL1256682 CHEMBL1256682 antagonist GuideToPharmacologyInteractions
CHRM1 1128 METHOCTRAMINE CHEMBL27673 antagonist GuideToPharmacologyInteractions
CHRM1 1128 OTENZEPAD CHEMBL17045 antagonist GuideToPharmacologyInteractions
CHRM1 1128 OXYBUTYNIN CHEMBL1231 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND
CHRM1 1128 PROPANTHELINE CHEMBL1180725 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND
CHRM1 1128 SOLIFENACIN CHEMBL1734 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND
CHRM1 1128 QUINUCLIDINYL BENZILATE CHEMBL12980 antagonist GuideToPharmacologyInteractions
CHRM1 1128 TRIHEXYPHENIDYL CHEMBL1490 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, TTD
CHRM1 1128 TRIPITRAMINE CHEMBL265256 antagonist GuideToPharmacologyInteractions
CHRM1 1128 PILOCARPINE HYDROCHLORIDE CHEMBL1200330 agonist ChemblInteractions
CHRM1 1128 ETHOPROPAZINE HYDROCHLORIDE CHEMBL1200970 antagonist ChemblInteractions
CHRM1 1128 BENZTROPINE CHEMBL1201203 antagonist TdgClinicalTrial, TEND, TTD
CHRM1 1128 DESIPRAMINE CHEMBL72 TdgClinicalTrial, TEND
CHRM1 1128 CEVIMELINE CHEMBL168815 TdgClinicalTrial, TEND
CHRM1 1128 HOMATROPINE METHYLBROMIDE CHEMBL1200851 TdgClinicalTrial, TEND
CHRM1 1128 METHYLSCOPOLAMINE CHEMBL376897 TdgClinicalTrial, TEND
CHRM1 1128 GLYCOPYRROLATE BROMIDE CHEMBL1201027 antagonist ChemblInteractions
CHRM1 1128 OXYPHENCYCLIMINE HYDROCHLORIDE CHEMBL1200891 antagonist ChemblInteractions
CHRM1 1128 OXYPHENONIUM CHEMBL1201286 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17139284, 17016423, 3580704
CHRM1 1128 OLANZAPINE CHEMBL715 antagonist TdgClinicalTrial, TEND, DrugBank 10227113, 17316700, 17848919
CHRM1 1128 PROCYCLIDINE CHEMBL86715 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423, 20624420, 2253700, 1426023, 2027917
CHRM1 1128 LOXAPINE CHEMBL831 binder DrugBank
CHRM1 1128 PROMAZINE CHEMBL564 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 TRIFLUPROMAZINE CHEMBL570 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423, 4152054
CHRM1 1128 ANISOTROPINE METHYLBROMIDE CHEMBL1578 antagonist TdgClinicalTrial, ChemblInteractions, TEND, DrugBank 17139284, 17016423, 4555460, 20391952, 6897316
CHRM1 1128 GLYCOPYRROLATE CHEMBL1201335 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, DrugBank, TTD 11752352, 17139284, 17016423, 8249551
CHRM1 1128 TOLTERODINE CHEMBL1382 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, DrugBank 14769832, 17139284, 17016423
CHRM1 1128 MEPENZOLATE CHEMBL524004 antagonist DrugBank 7122991, 7623487, 2791613
CHRM1 1128 CHEMBL130715 CHEMBL130715 agonist GuideToPharmacologyInteractions
CHRM1 1128 GLYBURIDE CHEMBL472 agonist GuideToPharmacologyInteractions
CHRM1 1128 SABCOMELINE CHEMBL134641 agonist GuideToPharmacologyInteractions
CHRM1 1128 K-252A CHEMBL281948 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 STAUROSPORINE CHEMBL388978 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 BIPERIDEN (CHEMBL1101) CHEMBL1101 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, TTD
CHRM1 1128 DOTHIEPIN (CHEMBL1492500) CHEMBL1492500 antagonist GuideToPharmacologyInteractions
CHRM1 1128 COENZYME_A CHEMBL1213327 antagonist GuideToPharmacologyInteractions
CHRM1 1128 TIOTROPIUM (CHEMBL1900528) CHEMBL1900528 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL1233686 CHEMBL1233686 antagonist GuideToPharmacologyInteractions
CHRM1 1128 SABCOMELINE HYDROCHLORIDE CHEMBL2107146 agonist TTD
CHRM1 1128 BIPERIDEN LACTATE CHEMBL1201067 antagonist ChemblInteractions
CHRM1 1128 DICYCLOMINE HYDROCHLORIDE CHEMBL1200479 antagonist ChemblInteractions
CHRM1 1128 METHIXENE HYDROCHLORIDE CHEMBL1200426 antagonist ChemblInteractions
CHRM1 1128 REVATROPATE CHEMBL2105235 antagonist TTD
CHRM1 1128 TALSACLIDINE FUMARATE CHEMBL2107204 agonist TTD
CHRM1 1128 SUXAMETHONIUM CHEMBL703 TdgClinicalTrial, TEND
CHRM1 1128 FLAVOXATE CHEMBL1493 TdgClinicalTrial, TEND
CHRM1 1128 TRIHEXYPHENIDYL HYDROCHLORIDE CHEMBL1092 antagonist ChemblInteractions
CHRM1 1128 DIPHEMANIL METHYLSULFATE CHEMBL1200880 antagonist ChemblInteractions
CHRM1 1128 ASM-024 CHEMBL3707249 antagonist ChemblInteractions
CHRM1 1128 TRIDIHEXETHYL CHLORIDE CHEMBL1200771 antagonist ChemblInteractions
CHRM1 1128 PROCYCLIDINE HYDROCHLORIDE CHEMBL1761 antagonist ChemblInteractions
CHRM1 1128 INDACATEROL CHEMBL1095777 TdgClinicalTrial
CHRM1 1128 CYCRIMINE HYDROCHLORIDE CHEMBL1200828 antagonist ChemblInteractions
CHRM1 1128 BENZTROPINE MESYLATE CHEMBL1200383 antagonist GuideToPharmacologyInteractions, ChemblInteractions
CHRM1 1128 TERFENADINE CHEMBL17157 binder DrugBank 10212017
CHRM1 1128 BUCLIZINE CHEMBL1201271 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 CLOZAPINE CHEMBL42 antagonist, allosteric modulator GuideToPharmacologyInteractions, DrugBank 17848919
CHRM1 1128 OXYPHENCYCLIMINE CHEMBL1495 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423, 3247303, 1426023
CHRM1 1128 PROPIOMAZINE CHEMBL1201210 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 MINAPRINE CHEMBL278819 agonist DrugBank 18045214, 2586634
CHRM1 1128 METHANTHELINE CHEMBL1201264 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 CYCRIMINE CHEMBL1201227 antagonist, binder TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17139284, 17016423, 1267542
CHRM1 1128 DIPHENIDOL CHEMBL936 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423, 1863523
CHRM1 1128 CHLORPROTHIXENE CHEMBL908 antagonist DrugBank 7855217
CHRM1 1128 CHEMBL1242950 CHEMBL1242950 agonist, allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 ACETYLCHOLINE CHEMBL667 agonist GuideToPharmacologyInteractions
CHRM1 1128 ARECAIDINE PROPARGYL ESTER CHEMBL128365 agonist GuideToPharmacologyInteractions
CHRM1 1128 FURTRETHONIUM CHEMBL2110739 agonist GuideToPharmacologyInteractions
CHRM1 1128 5-METHYLFURMETHIODIDE CHEMBL1316369 agonist GuideToPharmacologyInteractions
CHRM1 1128 FLUOROURACIL CHEMBL185 agonist GuideToPharmacologyInteractions
CHRM1 1128 OXOTREMORINE CHEMBL7634 agonist GuideToPharmacologyInteractions
CHRM1 1128 ALCURONIUM CHEMBL1180293 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL343796 CHEMBL343796 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL139677 CHEMBL139677 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 STRYCHNINE CHEMBL227934 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL1256845 CHEMBL1256845 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 SALICYLIC ACID CHEMBL424 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL523685 CHEMBL523685 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 4-DAMP CHEMBL76897 antagonist GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL279453 CHEMBL279453 antagonist GuideToPharmacologyInteractions
CHRM1 1128 DICYCLOMINE CHEMBL1123 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND, TTD
CHRM1 1128 CHEMBL580785 CHEMBL580785 antagonist GuideToPharmacologyInteractions
CHRM1 1128 HIMBACINE CHEMBL277642 antagonist GuideToPharmacologyInteractions
CHRM1 1128 HYDROCHLORIC ACID CHEMBL1231821 antagonist GuideToPharmacologyInteractions
CHRM1 1128 CEVIMELINE HYDROCHLORIDE CHEMBL2218917 agonist ChemblInteractions
CHRM1 1128 CLIDINIUM BROMIDE CHEMBL1200950 antagonist ChemblInteractions
CHRM1 1128 METHSCOPOLAMINE BROMIDE CHEMBL1201024 antagonist ChemblInteractions
CHRM1 1128 BATEFENTEROL CHEMBL3039518 agonist TTD
CHRM1 1128 PROMETHAZINE CHEMBL643 TdgClinicalTrial, TEND
CHRM1 1128 SOBETIROME CHEMBL107400 agonist TTD
CHRM1 1128 METOCLOPRAMIDE CHEMBL86 TdgClinicalTrial
CHRM1 1128 CYCLOPENTOLATE CHEMBL1201338 TdgClinicalTrial, TEND
CHRM1 1128 TROSPIUM CHEMBL1888176 TdgClinicalTrial, TEND
CHRM1 1128 XANOMELINE TARTARIC ACID CHEMBL2336050 agonist TTD
CHRM1 1128 CARBINOXAMINE CHEMBL864 TdgClinicalTrial, TEND
CHRM1 1128 ARIPIPRAZOLE CHEMBL1112 antagonist DrugBank 17848919
CHRM1 1128 DOXYLAMINE CHEMBL1004 antagonist DrugBank 17139284, 17016423
CHRM1 1128 ETHOPROPAZINE CHEMBL1206 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17016423, 2236897, 2904117
CHRM1 1128 HYOSCYAMINE CHEMBL1331216 antagonist DrugBank 17139284, 17016423, 9732369
CHRM1 1128 DARIFENACIN CHEMBL1346 antagonist GuideToPharmacologyInteractions, DrugBank 10374898, 18046909
CHRM1 1128 TRIDIHEXETHYL CHEMBL1201354 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 AMOXAPINE CHEMBL1113 antagonist DrugBank 9589848, 6130192, 6086881
CHRM1 1128 BENZQUINAMIDE CHEMBL1201250 antagonist TdgClinicalTrial, TEND, DrugBank 17139284, 17016423
CHRM1 1128 CLIDINIUM CHEMBL620 antagonist TdgClinicalTrial, TEND, DrugBank, TTD 11752352, 17139284, 17016423
CHRM1 1128 BROMPHENIRAMINE CHEMBL811 antagonist DrugBank 10212017
CHRM1 1128 FLUPENTIXOL CHEMBL54661 antagonist DrugBank 7052344
CHRM1 1128 PILOCARPINE CHEMBL550 agonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND, DrugBank 17139284, 17016423, 18824613
CHRM1 1128 UMECLIDINIUM CHEMBL1187833 agonist, antagonist GuideToPharmacologyInteractions, DrugBank, TTD 23435542
CHRM1 1128 CHEMBL99521 CHEMBL99521 agonist GuideToPharmacologyInteractions
CHRM1 1128 ERIBAXABAN CHEMBL476186 agonist GuideToPharmacologyInteractions
CHRM1 1128 ETHACRYNIC ACID CHEMBL456 agonist GuideToPharmacologyInteractions
CHRM1 1128 XANOMELINE CHEMBL21536 agonist GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL2206331 CHEMBL2206331 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 VINBURNINE CHEMBL1892145 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 VINCAMINE CHEMBL1165342 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL608532 CHEMBL608532 allosteric modulator GuideToPharmacologyInteractions
CHRM1 1128 AMITRIPTYLINE CHEMBL629 antagonist GuideToPharmacologyInteractions
CHRM1 1128 ATROPINE CHEMBL517712 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND
CHRM1 1128 IPRATROPIUM CHEMBL1621597 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, TEND
CHRM1 1128 CITRIC ACID CHEMBL1261 antagonist GuideToPharmacologyInteractions
CHRM1 1128 CHEMBL1628667 CHEMBL1628667 antagonist GuideToPharmacologyInteractions
CHRM1 1128 OXYPHENONIUM BROMIDE CHEMBL1200906 antagonist ChemblInteractions
CHRM1 1128 ISOPROPAMIDE IODIDE CHEMBL1200347 antagonist ChemblInteractions
CHRM1 1128 DAROTROPIUM BROMIDE CHEMBL2103803 antagonist ChemblInteractions
CHRM1 1128 Afacifenacin CHEMBL3545165 antagonist ChemblInteractions
CHRM1 1128 PROPANTHELINE BROMIDE CHEMBL1240 antagonist ChemblInteractions
CHRM1 1128 BIPERIDEN HYDROCHLORIDE CHEMBL1201035 antagonist ChemblInteractions
CHRM1 1128 HEXOCYCLIUM METHYLSULFATE CHEMBL1626570 antagonist ChemblInteractions
CHRM1 1128 DIPHENIDOL HYDROCHLORIDE CHEMBL1529 antagonist ChemblInteractions
CHRM1 1128 THIETHYLPERAZINE CHEMBL1378 TdgClinicalTrial, TEND
CHRM1 1128 DOXEPIN CHEMBL1628227 TdgClinicalTrial
CHRM1 1128 DAROTROPIUM CHEMBL2110584 agonist TTD
CHRM1 1128 MEPENZOLATE BROMIDE CHEMBL1724 antagonist ChemblInteractions
CHRM1 1128 ATROPINE SULFATE CHEMBL2146146 antagonist ChemblInteractions
CHRM1 1128 COCAINE CHEMBL370805 antagonist DrugBank 15351386
CHRM1 1128 SCOPOLAMINE CHEMBL1187846 antagonist TdgClinicalTrial, GuideToPharmacologyInteractions, ChemblInteractions, TEND, DrugBank 14534362, 20398692
CHRM1 1128 FESOTERODINE CHEMBL1201764 antagonist TEND, DrugBank 12076307
CHRM1 1128 CINNARIZINE CHEMBL43064 binder DrugBank 11180191

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID