PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
COPS3	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
FBXO25	1	ACTG1	5	affinity chromatography technology	Teixeira FR (2010)	1
FBXO25	1	SAMHD1	3	enzymatic study	Teixeira FR (2013)	1
ELOC	0	ELOB	1	two hybrid, pull down, pull down, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, x-ray crystallography, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, pull down, two hybrid, biochemical, biochemical, two hybrid	Rual JF (2005), Ohh M (1999), Aso T (1995), Li Z (2002), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Lievens S (2009), Brower CS (1999), Stebbins CE (1999), Pause A (1999), Pause A (1999), Havugimana PC (2012), Wang X (2013), Kristensen AR (2012), Costessi A (2011), Rolland T (2014), Kim DY (2013), Wan C (2015), Yu H (2011)	21
DTL	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Higa LA (2006), Higa LA (2006), Sertic S (2013), Shibata E (2014), Hein MY (2015), Shibata E (2011), Higa LA (2006), Higa LA (2006)	9
FBXO7	1	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL3	17	CUL1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Bennett EJ (2010), Bennett EJ (2010), Wan C (2015)	3
ELAVL1	0	TP53	0	affinity chromatography technology	Galban S (2003)	1
DTL	0	UBE2E3	0	affinity chromatography technology	Shibata E (2011)	1
ELAVL1	0	UBE2D3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
SKP1	0	MAGEC2	0	affinity chromatography technology	Hao J (2015)	1
CUL5	1	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	FBXO22	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
HIST1H4A	0	CUL1	7	biochemical	Kristensen AR (2012)	1
CUL1	7	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	FEM1B	1	affinity chromatography technology	Bennett EJ (2010)	1
UBE2E3	0	CUL4A	2	pull down	Plafker KS (2009)	1
FBXO44	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Yoshida Y (2011)	2
TP53	0	COPS4	0	affinity chromatography technology	Bhansali M (2014)	1
CUL2	3	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
ING3	3	APP	1	pull down	Olah J (2011)	1
CUL2	3	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015)	3
NEDD4	2	RBX1	2	affinity chromatography technology	Liu J (2014)	1
CUL5	1	ELOC	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology	Kamura T (2001), Nishiya T (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Kershaw NJ (2014), Huttlin EL (2017)	18
DDA1	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Jin J (2006), Hein MY (2015)	3
FBXO6	0	HSPA1A	0	affinity chromatography technology	Liu B (2012)	1
RBX1	2	SKP2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Ohta T (2001), Saiga T (2009), Rodier G (2008), Zhou W (2014), Zhou W (2014)	6
UBE2G1	2	APP	1	pull down	Olah J (2011)	1
FBXO7	1	RPS6KB1	1	enzymatic study	Teixeira FR (2016)	1
DCAF1	5	CUL4A	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahn J (2010), Belzile JP (2007), He YJ (2006), McCall CM (2008), McCall CM (2008), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Kyei GB (2015)	14
MED8	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Brower CS (2002), Brower CS (2002)	2
DDB1	6	COPS6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009)	5
NEDD8	0	FEM1B	1	affinity chromatography technology	Bennett EJ (2010)	1
HSPB1	2	FXR1	0	two hybrid	Katsogiannou M (2014)	1
MAPK8IP2	5	HSPA1A	0	two hybrid, affinity chromatography technology	Grossmann A (2015), Grossmann A (2015)	2
CDC34	3	CUL3	17	pull down	Plafker KS (2009)	1
DCUN1D1	0	COPS3	1	affinity chromatography technology	Bennett EJ (2010)	1
HIF1A	1	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chew EH (2007), Sufan RI (2006), Luo W (2010), Heir P (2013), Russell RC (2008)	5
FBXW2	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Xu J (2017), Xu J (2017), Xu J (2017), Huttlin EL (2017)	4
ELOC	0	GHR	1	unspecified method	Bulatov E (2015)	1
COPS5	0	ESR1	0	affinity chromatography technology	Callige M (2005)	1
CUL4A	2	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Ito T (2010), Bennett EJ (2010), Liu Y (2015), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	14
LRR1	1	ELOB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kamura T (2004), Kamura T (2004)	3
APP	1	HSPA8	4	affinity chromatography technology	Yamamoto YH (2010)	1
HOXB4	2	DDB1	6	affinity chromatography technology	Ohno Y (2010)	1
COPS6	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
UBXN1	0	HIF1A	1	affinity chromatography technology	Alexandru G (2008)	1
UBE2D3	1	NEDD8	0	biochemical	Wan C (2015)	1
GATA2	0	RBX1	2	affinity chromatography technology	Nakajima T (2015)	1
DCUN1D1	0	VHL	0	affinity chromatography technology	Heir P (2013)	1
FRZB	2	RBX1	2	two hybrid	Vinayagam A (2011)	1
COPS6	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
CUL4A	2	GLMN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tron AE (2012), Tron AE (2012), Huttlin EL (2017)	3
DDB1	6	AHR	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kawajiri K (2009), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	4
COPS3	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
FBXO7	1	UBE2D1	0	pull down	Teixeira FR (2016)	1
HIF1A	1	FBXW7	2	affinity chromatography technology	Cassavaugh JM (2011)	1
UBXN7	3	ELOB	1	affinity chromatography technology	Alexandru G (2008)	1
RBX1	2	CUL2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Dias DC (2002), Ohta T (1999), Ohta T (1999), Maine GN (2007), Hu J (2004), Furukawa M (2002), Mao X (2011), Sufan RI (2006), Sufan RI (2006), Sufan RI (2006), Brower CS (2002), Tron AE (2012), Kamura T (2004), Kristensen AR (2012), Costessi A (2011), Huang DT (2009), Kamura T (1999), Kamura T (1999), Xu J (2015), Cardote TAF (2017)	20
HSPA1A	0	HSPA8	4	biochemical, biochemical	Havugimana PC (2012), Kristensen AR (2012)	2
CUL1	7	MAGEC2	0	affinity chromatography technology, imaging technique, affinity chromatography technology	Hao J (2015), Hao J (2015), Hao J (2015)	3
HSPB1	2	CASP3	0	affinity chromatography technology	Gibert B (2012)	1
FBXW8	2	CUL7	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Huber C (2005), Huber C (2005), Okabe H (2007), Ponyeam W (2012), Litterman N (2011), Skaar JR (2007), Skaar JR (2007), Tsutsumi T (2008), Kong C (2012), Xu X (2012), Xu X (2008), Xu X (2008)	13
CUL1	7	EZH2	4	affinity chromatography technology	Sahasrabuddhe AA (2014)	1
KEAP1	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang DD (2005), Ichikawa T (2009), Lau A (2010), Li Y (2012), Niture SK (2013), Kaspar JW (2012), Kaspar JW (2012), Zhang DD (2004), Lo SC (2006)	9
ELAVL1	0	DIO2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
RHOBTB3	1	VHL	0	affinity chromatography technology, pull down, two hybrid	Zhang CS (2015), Zhang CS (2015), Zhang CS (2015)	3
CUL5	1	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
SUV39H1	0	DNMT3A	17	pull down, affinity chromatography technology	Fuks F (2003), Fuks F (2003)	2
COPS4	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
BTRC	1	UBE2D1	0	affinity chromatography technology	Fernandez-Sanchez ME (2010)	1
PSMA6	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bloom J (2006), Bloom J (2006), Bloom J (2006), Bennett EJ (2010)	4
SESN2	3	RBX1	2	affinity chromatography technology	Bae SH (2013)	1
ARID1B	80	ELOC	0	pull down, affinity chromatography technology	Li XS (2010), Li XS (2010)	2
SMAD3	1	SUV39H1	0	affinity chromatography technology	Wakabayashi Y (2011)	1
DCUN1D4	0	CUL4B	8	pull down, enzymatic study	Monda JK (2013), Monda JK (2013)	2
GLMN	2	FBXW7	2	pull down	Tron AE (2012)	1
COPS6	0	FBXO22	1	affinity chromatography technology	Sowa ME (2009)	1
COPS5	0	FBXO31	4	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Zhu Z (2017)	3
CAND1	2	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Jin J (2006), Wang H (2006), Higa LA (2006), Higa LA (2006), Kawajiri K (2009), Bennett EJ (2010), Havugimana PC (2012), Ji Q (2014), Wan C (2015), Hein MY (2015), Mo Y (2017), Mo Y (2017), Yang Y (2015), Yang Y (2015), Yang Y (2015), Higa LA (2006), Higa LA (2006), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	23
CUL4A	2	TP53	0	affinity chromatography technology	Banks D (2006)	1
FBXO6	0	COPS5	0	affinity chromatography technology	Liu B (2012)	1
ELAVL1	0	UBE2G1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
SKP1	0	FBXL5	3	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Winston JT (1999), Vashisht AA (2009), Salahudeen AA (2009), Vinas-Castells R (2013), Moroishi T (2014), Moroishi T (2014), Rolland T (2014), Yu H (2011), Wu WD (2016), Huttlin EL (2017)	10
RBX1	2	MYB	3	pull down	Kanei-Ishii C (2008)	1
CDC34	3	CUL2	3	pull down	Sandoval D (2014)	1
HIST1H1A	0	DDB1	6	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCUN1D1	0	KBTBD6	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	COPS5	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
CDC34	3	HIF1A	1	enzymatic study	Miller F (2005)	1
FBXO18	0	SKP1	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kim J (2002), Kim J (2002), Kim J (2002), Kim JH (2004), Jeong YT (2013), Hauri S (2016)	6
BTRC	1	UBE2D3	1	pull down	Chong RA (2014)	1
PRAME	2	ELOB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Costessi A (2011), Costessi A (2011), Costessi A (2012), Costessi A (2012), Wadelin FR (2013), Wadelin FR (2013), Costessi A (2011)	7
CAND1	2	SKP1	0	affinity chromatography technology, affinity chromatography technology	Zheng J (2002), Bennett EJ (2010)	2
FBXO21	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang C (2015), Zhang C (2015), Hauri S (2016)	3
COPS7A	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Bennett EJ (2010), Huang X (2016), Reitsma JM (2017)	4
UBE2D3	1	TRIM27	2	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
FBXO6	0	OS9	4	affinity chromatography technology	Liu B (2012)	1
FBXO27	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Yoshida Y (2011)	2
RBX1	2	UBE2D2	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Pick E (2007), Lan L (2012), Tsai WB (2010), Hrecka K (2007), Okuda H (2001), Tai T (2006), Ahn J (2011), Gong B (2010), Lu Y (2012), Ohta A (2013), da Silva Almeida AC (2013), Delucia M (2013), Scott DC (2014), Camp ND (2012), Kim S (2014), Theurillat JP (2014), Kigoshi Y (2011), Pashkova N (2010), Beck J (2013), Pierce WK (2015), Wu K (2016), Parameswaran B (2015), Simo S (2013), Groisman R (2006), Marzahn MR (2016), Courtheoux T (2016), Hasanov E (2017), Ferretti LP (2016), Zhou X (2017), Kroenke J (2014), Mulvaney KM (2016)	31
DCUN1D1	0	CAND1	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Bommelje CC (2013), Kim AY (2008), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	11
UVRAG	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Yang Y (2016), Yang Y (2016)	2
FBXO32	2	CDC34	3	pull down	Csibi A (2009)	1
NEDD4	2	SKP1	0	affinity chromatography technology	Liu J (2014)	1
CUL5	1	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
TP53	0	FBXO21	2	affinity chromatography technology	Fogeron ML (2013)	1
KLHL18	2	RBX1	2	affinity chromatography technology	Moghe S (2012)	1
UBXN7	3	DCAF1	5	affinity chromatography technology	Alexandru G (2008)	1
SERTAD1	0	SMAD3	1	two hybrid	Wang J (2011)	1
FBXO6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2007), Nelson RF (2007), Glenn KA (2008), Yoshida Y (2011), Liu B (2012), Liu B (2012), Huttlin EL (2015), Huttlin EL (2017), Reitsma JM (2017), Reitsma JM (2017)	10
COPS6	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CUL4B	8	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
KBTBD6	0	RBX1	2	affinity chromatography technology	Genau HM (2015)	1
UBE2M	0	KBTBD6	0	affinity chromatography technology	Huttlin EL (2017)	1
RBX1	2	UBE2D3	1	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down	Ohta T (2001), Sung CK (2011), DAngiolella V (2010), Kaur M (2012), Amir RE (2004), Tan M (2010), Lan L (2012), Banks D (2006), Saha A (2008), Furukawa M (2000), Gallegos JR (2008), Duan S (2011), He F (2013), Cui Y (2011), Teixeira FR (2013), Vinas-Castells R (2013), Chen Y (2009), Oda H (2010), Pick E (2007), Morimoto M (2003), Kim K (2013), Zhao D (2010), Jiang H (2005), Furukawa M (2005), Thirunavukarasou A (2015), Antonioli M (2014), Li D (2015), Watanabe K (2015), Niikura Y (2015), Zha Z (2015), Walter D (2016), Han XR (2016), Yi J (2015), Kim JH (2015), Moghe S (2012), Xu X (2008), Kuang P (2016), Kuang P (2016), Kuang P (2016), Kuchay S (2017), Xiao J (2015), McGourty CA (2016)	42
SKP2	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Bennett EJ (2010)	2
AIRE	3	CUL1	7	affinity chromatography technology	Shao W (2016)	1
ELAVL1	0	DDA1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
MYB	3	CUL4A	2	affinity chromatography technology	Kanei-Ishii C (2012)	1
SMAD3	1	BTRC	1	affinity chromatography technology	Wan M (2004)	1
UBE2M	0	KLHL18	2	affinity chromatography technology	Huttlin EL (2017)	1
RIPK4	0	FBXW11	2	affinity chromatography technology	Rodriguez J (2016)	1
DCUN1D3	1	CUL3	17	pull down, affinity chromatography technology, pull down, imaging technique, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	11
CUL5	1	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D2	0	CUL5	1	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
CUL4A	2	BTRC	1	affinity chromatography technology	He YJ (2006)	1
COPS5	0	LRRC14	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
CUL4B	8	PGAM5	4	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	DCUN1D1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
FBXL5	3	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
MED8	0	ELOC	0	affinity chromatography technology	Brower CS (2002)	1
DCUN1D1	0	ELOB	1	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	TP53	0	biochemical	Bech-Otschir D (2001)	1
ZC3HC1	1	APP	1	pull down	Olah J (2011)	1
RBX1	2	UBE2L6	0	pull down	Johansson P (2014)	1
CASP3	0	RBX1	2	affinity chromatography technology	Tan M (2006)	1
ELAVL1	0	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Abdelmohsen K (2009), Datta K (2005), Datta K (2005), Yuen JS (2007)	4
CUL9	5	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pei XH (2011), Pei XH (2011), Skaar JR (2007), Skaar JR (2007), Skaar JR (2007)	5
CUL4A	2	HAX1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	ERCC8	1	affinity chromatography technology	Bennett EJ (2010)	1
TRPC4AP	4	SKP2	2	affinity chromatography technology, affinity chromatography technology	Jamal A (2015), Jamal A (2015)	2
PGAM5	4	CUL3	17	affinity chromatography technology, affinity chromatography technology	Lo SC (2006), Bennett EJ (2010)	2
HSPA8	4	CCND1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jose-Eneriz ES (2008), Jose-Eneriz ES (2008), Truman AW (2012)	3
KLHL41	2	CUL3	17	affinity chromatography technology	Zhang DD (2005)	1
AIRE	3	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
DCUN1D1	0	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
ERCC8	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
GRK5	7	COPS7A	0	affinity chromatography technology	Wu Z (2012)	1
CUL1	7	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Cenciarelli C (1999), Sowa ME (2009), Megumi Y (2005), Davis M (2002), Kawakami T (2001), Read MA (2000), Suzuki H (1999), Kumar KG (2007), Schweitzer K (2007), Chua YS (2011), Winston JT (1999), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Latres E (1999), Yoshida Y (2007), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), Chung FZ (2014), Chen ZW (2015), Kim TY (2014), Read MA (2000), Coyaud E (2015), Low TY (2014), Coyaud E (2015), He N (2005), Huttlin EL (2017), Kuang P (2016), Reitsma JM (2017), Reitsma JM (2017)	34
DCUN1D1	0	COPS6	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	KLHL18	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	CUL3	17	affinity chromatography technology	Bennett EJ (2010)	1
ESR1	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tarallo R (2011), Cho J (2005), Cho J (2005)	3
RBX1	2	CORO7	0	affinity chromatography technology	Watanabe M (2011)	1
CUL3	17	DDB1	6	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Bennett EJ (2010), Sertic S (2013), Rossi M (2013), Jin J (2006), Shibata E (2011), Higa LA (2006)	7
RIPK4	0	RBX1	2	affinity chromatography technology	Rodriguez J (2016)	1
CUL4A	2	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Bennett EJ (2010), Huttlin EL (2017)	4
LRR1	1	UBE2D1	0	pull down	Starostina NG (2010)	1
FBXW7	2	RBX1	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2012), Matsumoto A (2011), Strohmaier H (2001), Ye M (2017)	4
HIST1H1C	2	RBX1	2	affinity chromatography technology, pull down	Kim K (2013), Kim K (2013)	2
COPS5	0	ELOC	0	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	DDB2	1	affinity chromatography technology	Olma MH (2009)	1
DCUN1D5	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
FBXW11	2	CDC34	3	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu K (2010), Chong RA (2014), Kim TY (2014), Coyaud E (2015), Low TY (2014)	5
CUL7	4	DDB1	6	affinity chromatography technology	Hanson D (2014)	1
FBXW7	2	COPS3	1	genetic interference	Bailey ML (2015)	1
CSNK1E	0	FBXW11	2	two hybrid	Wallach T (2013)	1
VHL	0	APP	1	pull down	Olah J (2011)	1
PSMA6	1	GPS1	1	affinity chromatography technology	Huang X (2005)	1
HIF1A	1	RBX1	2	affinity chromatography technology	Heir P (2013)	1
FBXO42	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun L (2009), Bennett EJ (2010), Huttlin EL (2017), Reitsma JM (2017)	4
CUL7	4	EEF1A1	0	affinity chromatography technology	Hanson D (2014)	1
ESR1	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Britschgi A (2017), Britschgi A (2017)	2
CCND1	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okabe H (2007), Lin DI (2006), Wei S (2008), Yu ZK (1998)	4
DDB1	6	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Min KW (2005), Emberley ED (2012), Olma MH (2009)	5
RFWD2	0	HSPA8	4	affinity chromatography technology	Yi C (2006)	1
CUL1	7	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXW11	2	MTSS1	1	affinity chromatography technology	Kim TY (2014)	1
COPS5	0	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
RHOB	0	CUL2	3	affinity chromatography technology, affinity chromatography technology	Xu J (2015), Xu J (2015)	2
DDB2	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, imaging technique	Kapetanaki MG (2006), Takedachi A (2010), Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Matsumoto S (2015), Hein MY (2015), Groisman R (2006), Groisman R (2006), Chitale S (2017)	10
CUL1	7	FBXO3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Shima Y (2008), Reitsma JM (2017)	3
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
UBXN7	3	KBTBD7	3	affinity chromatography technology	Alexandru G (2008)	1
FBXO6	0	GPS1	1	affinity chromatography technology	Liu B (2012)	1
SKP1	0	FBXO44	0	pull down, two hybrid, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Cenciarelli C (1999), Kumanomidou T (2010), Lievens S (2009), Yoshida Y (2007), Yoshida Y (2007), Glenn KA (2008), Yoshida Y (2011), Rolland T (2014), Huttlin EL (2015), Sjoegren B (2015), Kumanomidou T (2015), Huttlin EL (2017), Hauri S (2016)	14
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
COPS5	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Bennett EJ (2010), Oh W (2006), Chun Y (2013), Chun Y (2013), Chun Y (2013), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
FBXO25	1	HSPA8	4	affinity chromatography technology	Teixeira FR (2010)	1
KDM2B	11	RBX1	2	affinity chromatography technology	Han XR (2016)	1
FBXW7	2	COPS6	0	genetic interference	Bailey ML (2015)	1
DET1	2	COPS5	0	affinity chromatography technology	Huttlin EL (2017)	1
MKNK2	1	RICTOR	4	affinity chromatography technology	Hein MY (2015)	1
PML	7	RBX1	2	affinity chromatography technology, enzymatic study	Shima Y (2008), Yuan WC (2011)	2
GAN	4	ACTG1	5	affinity chromatography technology	Johnson-Kerner BL (2015)	1
CUL3	17	HAX1	1	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
CUL4A	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
EEF1A1	0	HSPA1A	0	biochemical	Havugimana PC (2012)	1
COPS5	0	CAND1	2	biochemical, affinity chromatography technology	Bornstein G (2006), Bennett EJ (2010)	2
COPS3	1	FEM1B	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
GAN	4	TUBA1B	0	affinity chromatography technology	Johnson-Kerner BL (2015)	1
EZH2	4	HSPA1A	0	affinity chromatography technology	Cao Q (2014)	1
CUL4B	8	EZH2	4	affinity chromatography technology	Yang Y (2015)	1
PRAME	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down	Costessi A (2011), Costessi A (2012), Costessi A (2011)	3
CDC34	3	BTRC	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, bioid, affinity chromatography technology	Semplici F (2002), Cenciarelli C (1999), Sowa ME (2009), Fernandez-Sanchez ME (2010), Chong RA (2014), Burrows AC (2012), Coyaud E (2015), Huttlin EL (2017)	8
CUL4B	8	CBX5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	4
DET1	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Wertz IE (2004), Vitari AC (2011), Lu G (2014), Lu G (2014), Pick E (2007), Huttlin EL (2017)	7
FBXW11	2	MAPK8IP2	5	affinity chromatography technology	Low TY (2014)	1
EZH2	4	ACTG1	5	affinity chromatography technology	Cao Q (2014)	1
PML	7	EZH2	4	affinity chromatography technology	Villa R (2007)	1
DET1	2	UBE2E3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Pick E (2007), Pick E (2007), Huttlin EL (2017)	4
AIRE	3	HSPA1A	0	affinity chromatography technology	Fogeron ML (2013)	1
CUL5	1	ELOB	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down	Kamura T (2001), Nie L (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Antonioli M (2014), Kershaw NJ (2014)	18
CASP3	0	FBXW11	2	affinity chromatography technology	Tan M (2006)	1
MCM10	2	APP	1	pull down, affinity chromatography technology	Olah J (2011), Huttlin EL (2017)	2
CUL4A	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Pick E (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006)	7
RBX1	2	CUL4B	8	affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, imaging technique	Dias DC (2002), Ji Q (2014), Huang DT (2009), Hein MY (2015), Yang Y (2015)	5
GPS1	1	SKP2	2	affinity chromatography technology	Lyapina S (2001)	1
SKP2	2	DCUN1D3	1	affinity chromatography technology	Zhang S (2016)	1
DCUN1D1	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Wu K (2011), Bennett EJ (2010), Huang G (2011), Monda JK (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Huang G (2014), Huang G (2014), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	16
DET1	2	COPS6	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL2	3	GLMN	2	affinity chromatography technology, affinity chromatography technology	Tron AE (2012), Huttlin EL (2017)	2
AHR	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	5
COPS5	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
ERCC8	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Groisman R (2006)	8
DNMT3A	17	CBX5	3	affinity chromatography technology, affinity chromatography technology	Lehnertz B (2003), Smallwood A (2007)	2
FBXW11	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Suzuki H (2000), Sowa ME (2009), Fuchs SY (1999), Tan P (1999), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), DAnnibale S (2014), Kim TY (2014), Coyaud E (2015), Low TY (2014), Chen TC (2014), Reitsma JM (2017)	14
FBXW11	2	KEAP1	0	affinity chromatography technology	Kim TY (2014)	1
COPS4	0	FBXO17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
CUL3	17	KBTBD6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Genau HM (2015), Genau HM (2015), Huttlin EL (2017)	5
RBX1	2	CBX5	3	affinity chromatography technology	Yang Y (2015)	1
RICTOR	4	FBXW7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guo Z (2012), Koo J (2015), Koo J (2015)	3
UBE2D2	0	RNF126	2	two hybrid, pull down, pull down, pull down	Markson G (2009), Hou X (2012), Smith CJ (2013), Delker RK (2013)	4
COPS6	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL9	5	UBE2G1	2	pull down	Gama V (2014)	1
UBXN7	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012)	2
KCTD17	0	RBX1	2	affinity chromatography technology, pull down, affinity chromatography technology	Kasahara K (2014), Kasahara K (2014), Kasahara K (2014)	3
UBE2D1	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
COPS6	0	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
UBE2D1	0	TRIM27	2	two hybrid, two hybrid, two hybrid, affinity chromatography technology	Markson G (2009), Napolitano LM (2011), Napolitano LM (2011), Napolitano LM (2011)	4
DCUN1D3	1	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
AHR	3	RBX1	2	affinity chromatography technology	Ohtake F (2007)	1
COPS5	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Sertic S (2013), Higa LA (2006), Higa LA (2006)	5
UBXN7	3	SKP1	0	affinity chromatography technology	Alexandru G (2008)	1
FBXW11	2	UBE2G2	0	affinity chromatography technology	Low TY (2014)	1
CUL4A	2	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Angers S (2006), Hu J (2004), Chua YS (2011), Tron AE (2012), Zheng J (2002), He YJ (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Olma MH (2009), Olma MH (2009), Yang Y (2016), Yang Y (2016)	18
CUL4A	2	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Kapetanaki MG (2006), Matsuda N (2005), Higa LA (2006), Nag A (2001), Takedachi A (2010), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), Groisman R (2003), Groisman R (2003), Hrecka K (2007), Shiyanov P (1999), Shiyanov P (1999), Bennett EJ (2010), Kulaksiz G (2005), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Groisman R (2003), Huttlin EL (2015), Hein MY (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Fantini D (2017)	31
ZC3HC1	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down	Bassermann F (2007), Bassermann F (2005), Bassermann F (2005)	3
NEDD8	0	ELOC	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
IP6K1	5	DDB1	6	affinity chromatography technology, pull down	Rao F (2014), Rao F (2014)	2
FBXO25	1	RBX1	2	affinity chromatography technology	Maragno AL (2006)	1
DAB2IP	3	SKP1	0	affinity chromatography technology	Dai X (2014)	1
COPS7A	0	PTGS2	0	affinity chromatography technology, pull down	Neuss H (2007), Neuss H (2007)	2
BTRC	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Strack P (2000), Margottin F (1998), Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Watanabe N (2004), Wu G (2003), Kawakami T (2001), Hattori K (1999), Hattori K (1999), Hattori K (1999), Kitagawa M (1999), Hart M (1999), Su Y (2008), Banerjee S (2010), Winston JT (1999), Winston JT (1999), Estrabaud E (2007), Latres E (1999), Latres E (1999), Liu J (2004), Lievens S (2009), Yoshida Y (2007), Yoshida Y (2007), Busino L (2012), Li T (2005), da Silva Almeida AC (2013), Sahasrabuddhe AA (2014), Choi BH (2014), Chong RA (2014), Kim TY (2014), Coyaud E (2015), Deng W (2015), Coyaud E (2015), Liu YQ (2015), He N (2005), Kuchay S (2017), Hauri S (2016)	40
CRBN	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu Q (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	4
COPS6	0	FBXL12	1	affinity chromatography technology	Bennett EJ (2010)	1
MCM10	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur M (2012), Kaur M (2012), Romani B (2015)	3
FBXO32	2	SKP1	0	pull down, affinity chromatography technology	Gomes MD (2001), Al-Yacoub N (2016)	2
ELAVL1	0	KMT5A	2	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXO42	0	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sun L (2009), Huttlin EL (2017), Hauri S (2016)	3
GATA2	0	SKP1	0	affinity chromatography technology	Nakajima T (2015)	1
SKP1	0	FBXL15	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lievens S (2009), Cui Y (2011), Huttlin EL (2015), Busino L (2007), Huttlin EL (2017), Hauri S (2016)	6
COPS4	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Shibata E (2011), Higa LA (2006)	3
MAP3K7	2	EZH2	4	two hybrid	Vinayagam A (2011)	1
NEDD8	0	GHR	1	unspecified method	Bulatov E (2015)	1
RBX1	2	ELOC	0	affinity chromatography technology	Brower CS (2002)	1
DCAF1	5	RBX1	2	pull down	Ahn J (2010)	1
CUL3	17	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Schenkova K (2012)	3
UBXN7	3	CSNK1E	0	affinity chromatography technology	Raman M (2015)	1
SKP1	0	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
HIF1A	1	HSPA8	4	affinity chromatography technology	Ferreira JV (2013)	1
COPS6	0	FBXO21	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D3	1	FBXO25	1	enzymatic study	Maragno AL (2006)	1
CDC34	3	FBXO7	1	enzymatic study, pull down	Cenciarelli C (1999), Vingill S (2016)	2
FBXO17	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017), Reitsma JM (2017)	5
CREB3L3	1	RBX1	2	affinity chromatography technology	Cheng Y (2016)	1
UVRAG	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Yang Y (2016), Yang Y (2016)	2
CUL3	17	GLMN	2	affinity chromatography technology	Tron AE (2012)	1
DDB1	6	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Angers S (2006), Behrends C (2010), Pick E (2007), Pick E (2007), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Jin J (2006), Wan C (2015)	10
NEDD8	0	UBE2D2	0	x-ray crystallography	Sakata E (2007)	1
COPS6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Reitsma JM (2017)	7
UBE2M	0	CUL7	4	enzymatic study	Ponyeam W (2012)	1
PRAME	2	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Costessi A (2011), Costessi A (2011), Bennett EJ (2010), Costessi A (2012), Costessi A (2012), Wadelin FR (2013), Costessi A (2011), Huttlin EL (2015), Huttlin EL (2017)	9
SKP2	2	RICTOR	4	affinity chromatography technology	Huttlin EL (2017)	1
PML	7	MYB	3	affinity chromatography technology, pull down	Dahle O (2004), Dahle O (2004)	2
RAG1	1	DCAF1	5	biochemical, pull down, affinity chromatography technology	Kassmeier MD (2011), Kassmeier MD (2011), Kassmeier MD (2011)	3
FBXO7	1	FBXW2	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
AHR	3	ESR1	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study	Wormke M (2003), Klinge CM (2000), MacPherson L (2009), Beischlag TV (2005), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	8
DCUN1D2	0	ELOB	1	affinity chromatography technology	Keuss MJ (2016)	1
FBXO6	0	HSPA8	4	affinity chromatography technology	Liu B (2012)	1
NEDD8	0	FBXW11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kim TY (2014), Coyaud E (2015)	3
DCUN1D5	0	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bommelje CC (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	4
CRBN	2	COPS7A	0	affinity chromatography technology	Kroenke J (2014)	1
COPS5	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Rao F (2014), Pick E (2012), Groisman R (2003), Groisman R (2003), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	19
RPS6KB1	1	VHL	0	genetic interference	Shen JP (2017)	1
KMT5A	2	CUL1	7	affinity chromatography technology	Wang Z (2015)	1
RIPK4	0	TUBA1B	0	affinity chromatography technology	Rodriguez J (2016)	1
UBE2M	0	CUL3	17	enzymatic study, pull down	Huang G (2011), Schumacher FR (2015)	2
BTRC	1	EZH2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sahasrabuddhe AA (2014), Sahasrabuddhe AA (2014), Huttlin EL (2017)	3
UBE2E3	0	DDB1	6	affinity chromatography technology	Pick E (2007)	1
SKP1	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Kumar R (2005), Wang W (2004), Ohta T (2001), Oshikawa K (2003), Liu J (2002), Li X (2003), Zhou W (2014), Zhou W (2014), Hao J (2015), Hauri S (2016)	11
KEAP1	0	CUL2	3	affinity chromatography technology	Zhang DD (2004)	1
MAP3K7	2	RBX1	2	two hybrid	Vinayagam A (2011)	1
SKP1	0	PSMA6	1	affinity chromatography technology	Hauri S (2016)	1
MAP3K7	2	SMAD3	1	imaging technique	Chen TC (2014)	1
UBE2M	0	APP	1	enzymatic study, pull down	Lee MR (2008), Olah J (2011)	2
ESR1	0	PGAM5	4	affinity chromatography technology	Tarallo R (2011)	1
DDA1	1	UBE2E3	0	affinity chromatography technology, biochemical, affinity chromatography technology	Pick E (2007), Pick E (2007), Pick E (2007)	3
NEDD8	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
TP53	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Latini P (2011)	2
FBXO6	0	HIST1H4A	0	affinity chromatography technology	Liu B (2012)	1
HIST1H1C	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Kim K (2013), Kim K (2013), Kim K (2013)	3
IP6K1	5	RBX1	2	affinity chromatography technology	Rao F (2014)	1
ACTG1	5	EEF1A1	0	biochemical	Wan C (2015)	1
FBXO42	0	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Sun L (2009), Sun L (2009), Sun L (2009), Sun L (2009), Sun L (2011), Sun L (2011)	6
UBXN7	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	3
FBXO11	14	RBX1	2	affinity chromatography technology	Abida WM (2007)	1
DCUN1D4	0	CUL1	7	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
PML	7	CUL1	7	affinity chromatography technology	Shima Y (2008)	1
RFWD2	0	UBE2D1	0	pull down, pull down	Choi HH (2011), Lu G (2014)	2
CCNF	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2011), Jeong YT (2013), Choudhury R (2017), Reitsma JM (2017)	4
SESN2	3	KEAP1	0	affinity chromatography technology	Bae SH (2013)	1
UBXN1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Hu Y (2017), Hu Y (2017)	4
COPS5	0	FBXO44	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXO7	1	SAMHD1	3	enzymatic study	Teixeira FR (2016)	1
KMT5A	2	DTL	0	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Centore RC (2010), Centore RC (2010), Abbas T (2010), Oda H (2010)	4
VHL	0	ELOB	1	affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Ohh M (1999), Min JH (2002), Hacker KE (2008), Menon S (2008), Kamura T (2002), Kamura T (2002), Kuznetsova AV (2003), Cockman ME (2000), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Kinoshita K (2007), Lai Y (2012), Mahrour N (2008), Mahrour N (2008), Grosfeld A (2007), Foxler DE (2012), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017)	43
CUL1	7	GLMN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Tron AE (2012), Tron AE (2012), Duda DM (2012), Tron AE (2012), Huttlin EL (2017)	5
GRK5	7	DDB2	1	affinity chromatography technology	Wu Z (2012)	1
CUL4B	8	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Higa LA (2006)	4
RBX1	2	CCND1	1	affinity chromatography technology	Maeda I (2001)	1
RFWD2	0	CDKN1B	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Choi HH (2015), Choi HH (2015), Choi HH (2015), Choi HH (2015), Choi HH (2015)	5
MAP4K1	1	FBXW7	2	affinity chromatography technology	Wang H (2014)	1
DCUN1D2	0	CAND1	2	affinity chromatography technology, affinity chromatography technology, pull down	Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	3
FBXO6	0	NEDD8	0	affinity chromatography technology	Liu B (2012)	1
DTL	0	GPS1	1	affinity chromatography technology	Higa LA (2006)	1
MKNK2	1	RBX1	2	two hybrid	Wang P (2006)	1
DDB1	6	FBXW8	2	affinity chromatography technology	He YJ (2006)	1
GRK5	7	COPS4	0	affinity chromatography technology	Wu Z (2012)	1
FBXO6	0	COPS6	0	affinity chromatography technology, affinity chromatography technology	Liu B (2012), Huttlin EL (2015)	2
COPS7A	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
DCUN1D5	0	DDB1	6	affinity chromatography technology	Keuss MJ (2016)	1
FBXO11	14	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Abida WM (2007), Duan S (2011), Rossi M (2013), Rolland T (2014), Kuchay S (2017), Hauri S (2016)	6
COPS6	0	UBE2M	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
NEDD8	0	KBTBD6	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	SKP1	0	affinity chromatography technology	Olma MH (2009)	1
RBX1	2	APP	1	pull down	Olah J (2011)	1
UBE2D2	0	UBE2M	0	biochemical	Havugimana PC (2012)	1
FBXO7	1	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
KBTBD7	3	KBTBD6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Genau HM (2015), Genau HM (2015), Hein MY (2015), Huttlin EL (2017)	5
NEDD8	0	PSMA2	1	affinity chromatography technology	Norman JA (2006)	1
CUL4A	2	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
FBXO44	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2007), Glenn KA (2008), Yoshida Y (2011), Bennett EJ (2010), Huttlin EL (2015), Sjoegren B (2015), Huttlin EL (2017), Reitsma JM (2017)	8
COPS5	0	CDKN1B	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Caballero OL (2002), Kouvaraki MA (2006), Kouvaraki MA (2006), Kouvaraki MA (2006), Hsieh YH (2007), Hwang CY (2004), Hwang CY (2004), Pan Y (2012), Wang Y (2008), Wang Y (2008), Yamaguchi F (2008), Wang Y (2014), Zhang H (2017), Zhang H (2017)	14
CUL2	3	GPS1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001)	2
CUL3	17	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	DDB1	6	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Lee JE (2011), Bennett EJ (2010), Lyapina S (2001), Reitsma JM (2017)	6
FXR1	0	CUL1	7	affinity chromatography technology	Qie S (2017)	1
RFWD2	0	CUL2	3	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	UBE2D3	1	pull down	Li X (2011)	1
CASP1	1	CUL3	17	affinity chromatography technology	Garstkiewicz M (2017)	1
FBXO32	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Al-Yacoub N (2016), Al-Yacoub N (2016), Reitsma JM (2017)	3
CUL7	4	APP	1	affinity chromatography technology	Hanson D (2014)	1
DDB1	6	CBX5	3	affinity chromatography technology	Yang Y (2015)	1
FBXO25	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teixeira FR (2010), Teixeira FR (2010), Hagens O (2006), Maragno AL (2006)	4
FBXW11	2	UBE2D3	1	pull down	Wu K (2010)	1
RBX1	2	UBE2R2	2	pull down, pull down	Pierce NW (2013), Hill S (2016)	2
CCND3	1	MYB	3	two hybrid	Wang J (2011)	1
FBXW11	2	TP53	0	affinity chromatography technology	Low TY (2014)	1
CUL1	7	MTSS1	1	affinity chromatography technology	Zhong J (2013)	1
FBXL15	0	RBX1	2	affinity chromatography technology	Cui Y (2011)	1
UBE2E2	1	APP	1	pull down	Olah J (2011)	1
CUL3	17	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina S (2001), Huttlin EL (2017)	3
ELOB	1	GHR	1	unspecified method	Bulatov E (2015)	1
TP53	0	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Lu D (2013), Ali A (2013)	4
CUL4B	8	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Jin J (2006), Hein MY (2015), Wang X (2017)	4
DET1	2	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL5	1	TRIM27	2	affinity chromatography technology	Bennett EJ (2010)	1
KMT5A	2	EZH2	4	biochemical	Cao R (2002)	1
FBXO7	1	PSMA2	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Vingill S (2016), Vingill S (2016), Vingill S (2016), Vingill S (2016), Vingill S (2016), Vingill S (2016), Teixeira FR (2016)	7
CUL2	3	UBE2D1	0	pull down, affinity chromatography technology, pull down	Sufan RI (2006), Sufan RI (2006), Maine GN (2007)	3
NEDD8	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
NEDD8	0	PSMA6	1	affinity chromatography technology	Norman JA (2006)	1
KEAP1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang XJ (2008), Rachakonda G (2008), Rachakonda G (2008), Nioi P (2007), Chew EH (2007), Chew EH (2007), Zhang DD (2005), Furukawa M (2005), Furukawa M (2005), Furukawa M (2005), Zhang DD (2004), Cullinan SB (2004), Kobayashi A (2004), Kobayashi A (2004), McMahon M (2006), Ichikawa T (2009), Lee DF (2009), Wong DP (2010), Wong DP (2010), Lau A (2010), Lau A (2010), Hur W (2010), Bennett EJ (2010), Yao JW (2012), Li Y (2012), Choo YY (2012), Kansanen E (2011), Kansanen E (2011), Niture SK (2013), Hast BE (2014), Cleasby A (2014), Kaspar JW (2012), Kaspar JW (2012), Su C (2015), Su C (2015), Huo L (2015), Dubiel D (2015), Lo SC (2006), Wu G (2017), Villeneuve NF (2013), Villeneuve NF (2013), Villeneuve NF (2013), Dong T (2016)	43
GAN	4	CUL3	17	affinity chromatography technology, affinity chromatography technology	Zhang DD (2005), Bennett EJ (2010)	2
RAG1	1	RBX1	2	affinity chromatography technology	Kassmeier MD (2011)	1
FBXW7	2	CDC34	3	pull down	Klotz K (2009)	1
COPS6	0	FBXO44	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
DCUN1D1	0	FEM1B	1	affinity chromatography technology	Bennett EJ (2010)	1
LRRC14	2	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
RICTOR	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
DCUN1D1	0	HIF1A	1	affinity chromatography technology	Heir P (2013)	1
COPS5	0	FBXO3	0	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	RHOB	0	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXO31	4	GHR	1	unspecified method	Bulatov E (2015)	1
RBX1	2	UBE2E2	1	pull down	Shibata E (2011)	1
COPS5	0	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
DET1	2	UBE2E2	1	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	KLHL18	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
FBXO25	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teixeira FR (2010), Teixeira FR (2010), Hagens O (2006), Maragno AL (2006)	4
TP53	0	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
COPS3	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Reitsma JM (2017)	4
COPS6	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
COPS5	0	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Bhansali M (2014), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	13
COPS5	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Groisman R (2006)	5
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
ENC1	0	RBX1	2	affinity chromatography technology	Zhang DD (2005)	1
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
FBXO7	1	PSMA6	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Vingill S (2016), Teixeira FR (2016)	3
RBX1	2	HSPA8	4	affinity chromatography technology	Dias DC (2002)	1
DCUN1D3	1	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
EZH2	4	HSPB1	2	affinity chromatography technology	Cao Q (2014)	1
VHL	0	ELOC	0	affinity chromatography technology, pull down, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Tsuchiya H (1996), Min JH (2002), Li Z (2002), Hacker KE (2008), Kim BY (2008), Baek JH (2007), Baek JH (2007), Kuznetsova AV (2003), Cockman ME (2000), Lisztwan J (1999), Stickle NH (2004), Lai Y (2011), Liu YV (2007), Norman JA (2006), Kinoshita K (2007), Cai Q (2010), Lai Y (2012), Miller F (2005), Mahrour N (2008), Mahrour N (2008), Russell RC (2011), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Stebbins CE (1999), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	48
FBXW7	2	MAGEC2	0	affinity chromatography technology	Hao J (2015)	1
CUL4B	8	DNMT3A	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	5
COPS5	0	FXR1	0	affinity chromatography technology	Bennett EJ (2010)	1
BTRC	1	KEAP1	0	affinity chromatography technology, bioid	Sowa ME (2009), Coyaud E (2015)	2
UBXN7	3	APP	1	pull down	Olah J (2011)	1
CUL3	17	ABTB2	2	pull down, affinity chromatography technology, affinity chromatography technology	Maezawa S (2008), Maezawa S (2008), Maezawa S (2008)	3
DTL	0	UBE2E2	1	affinity chromatography technology	Shibata E (2011)	1
COPS6	0	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Olma MH (2009), Kroenke J (2014)	3
KEAP1	0	PGAM5	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lo SC (2006), Lo SC (2006), Lo SC (2008), Lo SC (2008), Niture SK (2013), Lu K (2017)	7
GLMN	2	CUL9	5	affinity chromatography technology	Huttlin EL (2017)	1
ESR1	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Ohtake F (2007), Ohtake F (2007)	2
SAMHD1	3	RBX1	2	affinity chromatography technology	Morrissey C (2015)	1
RPS6KB1	1	APP	1	pull down	Olah J (2011)	1
DCUN1D1	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	SKP1	0	affinity chromatography technology	Rodriguez J (2016)	1
DDB1	6	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009)	3
CASP3	0	BTRC	1	affinity chromatography technology	Tan M (2006)	1
CSNK1E	0	CUL2	3	affinity chromatography technology	Varjosalo M (2013)	1
GATA2	0	CUL1	7	affinity chromatography technology	Nakajima T (2015)	1
FBXW7	2	FBXW2	0	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	SKP1	0	affinity chromatography technology, pull down, pull down, two hybrid, x-ray crystallography, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Strack P (2000), Ng RW (1998), Ng RW (1998), Schulman BA (2000), Cenciarelli C (1999), Marti A (1999), Sabile A (2006), Ji P (2004), Wang W (2004), Tokarz S (2004), Watanabe N (2004), Lin HK (2009), Lin HK (2009), Lin HK (2009), Price CT (2009), Huang Z (2004), Wu J (2012), Bashir T (2010), Saiga T (2009), Li T (2005), Carrano AC (1999), Wu J (2012), Wu L (2012), Rodier G (2008), Swarnalatha M (2013), Yumimoto K (2013), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Tian X (2015), Liu YQ (2015), Kuchay S (2017), Chan CH (2013), Chan CH (2013), Hauri S (2016), Ma X (2017)	37
NEDD8	0	ELOB	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
FBXO2	0	UBE2D3	1	pull down	Nelson RF (2006)	1
DCUN1D4	0	CUL2	3	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
CUL5	1	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
PML	7	FBXO3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shima Y (2008), Shima Y (2008), Shima Y (2008)	3
CCND3	1	MCM10	2	affinity chromatography technology, pull down	Rual JF (2005), Ramachandran N (2004)	2
FBXO42	0	RBX1	2	affinity chromatography technology	Sun L (2009)	1
CDC34	3	CORO7	0	affinity chromatography technology	Watanabe M (2011)	1
FBXO7	1	PRAME	2	enzymatic study	Teixeira FR (2016)	1
CUL4B	8	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Hein MY (2015)	4
GPS1	1	SKP1	0	affinity chromatography technology	Lyapina S (2001)	1
FBXW8	2	BTRC	1	affinity chromatography technology	Ponyeam W (2012)	1
COPS5	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXW11	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Suzuki H (2000), Sowa ME (2009), Sowa ME (2009), Coyaud E (2015), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017), Liu X (2017)	9
PSMA2	1	CRBN	2	affinity chromatography technology	Lee KM (2012)	1
TP53	0	CCND1	1	affinity chromatography technology	Yang P (2016)	1
BTRC	1	COPS6	0	affinity chromatography technology	Fang L (2015)	1
KDM2B	11	EZH2	4	affinity chromatography technology	Tzatsos A (2009)	1
CAND1	2	FXR1	0	affinity chromatography technology	Bennett EJ (2010)	1
SERTAD1	0	CCND2	2	pull down	Li J (2004)	1
FBXO7	1	ELOC	0	affinity chromatography technology	Hein MY (2015)	1
SAMHD1	3	EEF1A1	0	two hybrid, pull down, imaging technique, affinity chromatography technology	Morrissey C (2015), Morrissey C (2015), Morrissey C (2015), Morrissey C (2015)	4
FBXW2	0	SKP1	0	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Busino L (2012), Saiga T (2009), Watanabe N (2004), Winston JT (1999), Tian X (2015), Hauri S (2016)	9
ESR1	0	EZH2	4	pull down, affinity chromatography technology, affinity chromatography technology	Shi B (2007), Shi B (2007), Shi B (2007)	3
CUL4A	2	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
IBTK	3	COPS4	0	affinity chromatography technology	Pisano A (2015)	1
FBXO11	14	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abida WM (2007), Duan S (2011), Bennett EJ (2010), Jeong YT (2013), Reitsma JM (2017), Reitsma JM (2017)	6
CUL2	3	UBE2M	0	affinity chromatography technology	Bennett EJ (2010)	1
BTRC	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, bioid	Schweitzer K (2007), Schweitzer K (2007), Coyaud E (2015)	3
CUL4B	8	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
RBX1	2	CCND2	2	affinity chromatography technology	Maeda I (2001)	1
GPS1	1	RBX1	2	affinity chromatography technology	Lyapina S (2001)	1
UBXN7	3	RBX1	2	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bandau S (2012)	2
ELOC	0	SERTAD1	0	two hybrid	Ravasi T (2010)	1
UBE2M	0	COPS5	0	affinity chromatography technology	Huttlin EL (2017)	1
RBX1	2	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Furukawa M (2005), Hu J (2004), Furukawa M (2002), Ichikawa T (2009), Ichikawa T (2009), Lee DF (2009), Tron AE (2012), Oshikawa K (2003), Plafker KS (2009), Lu A (2013), Meyer-Schaller N (2009), Theurillat JP (2014), Huang DT (2009), Ibeawuchi SR (2015), Schumacher FR (2015), Kasahara K (2014), Kasahara K (2014)	18
RFWD2	0	SKP1	0	affinity chromatography technology	Olma MH (2009)	1
CUL3	17	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
DDA1	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Olma MH (2009), Olma MH (2009)	3
RBX1	2	DCUN1D3	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meyer-Schaller N (2009), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	4
FBXO31	4	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kumar R (2005), Kumar R (2005), Vadhvani M (2013), Jeffery JM (2017)	4
SAMHD1	3	DCAF1	5	affinity chromatography technology, enzymatic study, x-ray crystallography, pull down	Ahn J (2012), Delucia M (2013), Schwefel D (2014), Schwefel D (2014)	4
VHL	0	HSPA1A	0	biochemical	Feldman DE (2003)	1
ELAVL1	0	PTGS2	0	unspecified method, affinity chromatography technology, unspecified method	Kim I (2012), Kim I (2012), Sureban SM (2007)	3
CDC34	3	UBE2D3	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
DCUN1D1	0	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
CCND1	1	MCM10	2	pull down	Ramachandran N (2004)	1
MAPK8IP2	5	EZH2	4	two hybrid	Vinayagam A (2011)	1
PTGS2	0	COPS5	0	biochemical, affinity chromatography technology, pull down	Neuss H (2007), Neuss H (2007), Neuss H (2007)	3
FBXO27	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Yoshida Y (2011)	2
AHR	3	COPS5	0	affinity chromatography technology, affinity chromatography technology	Lee CC (2016), Lee CC (2016)	2
DDB2	1	DDB1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bergametti F (2002), Martinez E (2001), Guerrero-Santoro J (2008), Angers S (2006), Wang H (2006), Kapetanaki MG (2006), Kapetanaki MG (2006), Higa LA (2006), Takedachi A (2010), Fischer ES (2011), Scrima A (2008), Groisman R (2003), Groisman R (2003), Schroefelbauer B (2007), Kulaksiz G (2005), Inoki T (2004), Bontron S (2002), Rapic-Otrin V (2003), Olma MH (2009), Liu W (2000), Jin J (2006), Huttlin EL (2015), Zhao R (2014), Xie X (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Chitale S (2017), Fantini D (2017), Fantini D (2017), Ohtake F (2007)	31
ELAVL1	0	RPS6KB1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL5	1	GHR	1	unspecified method	Bulatov E (2015)	1
UBE2L3	1	CUL9	5	two hybrid, pull down	Moynihan TP (1999), Nikolaev AY (2003)	2
HSPB1	2	RBX1	2	two hybrid	Katsogiannou M (2014)	1
ARID1B	80	RBX1	2	affinity chromatography technology	Li XS (2010)	1
CAND1	2	HIST1H4A	0	affinity chromatography technology	Bennett EJ (2010)	1
RICTOR	4	RPS6KB1	1	pull down, imaging technique	Ali SM (2005), Chen TC (2014)	2
NEDD4	2	DCUN1D1	0	enzymatic study	Wu K (2011)	1
VHL	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Norman JA (2006)	2
DCUN1D5	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
CCND1	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, pull down	Wei S (2008), Wei S (2008), Wei S (2008)	3
EZH2	4	TUBA1B	0	affinity chromatography technology	Cao Q (2014)	1
DET1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Angers S (2006), Jin J (2006), Pick E (2007), Pick E (2007), Pick E (2007), Jin J (2006), Huttlin EL (2017)	8
SESN1	2	RBX1	2	affinity chromatography technology	Bae SH (2013)	1
ELOC	0	CORO7	0	affinity chromatography technology	Watanabe M (2011)	1
DCUN1D5	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bommelje CC (2013), Keuss MJ (2016), Keuss MJ (2016)	3
FBXO17	1	FBXW2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DCUN1D3	1	CUL1	7	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	8
KEAP1	0	ENC1	0	affinity chromatography technology	Wang XJ (2009)	1
UBE2M	0	DCUN1D3	1	pull down, pull down, pull down	Monda JK (2013), Meyer-Schaller N (2009), Keuss MJ (2016)	3
DDB1	6	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Wang H (2006), Kapetanaki MG (2006), Hu J (2004), Ahn J (2010), Fischer ES (2011), Groisman R (2006)	6
DCAF1	5	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009), Hein MY (2015)	3
DET1	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
CUL2	3	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
FBXO6	0	FBXW2	0	affinity chromatography technology	Liu B (2012)	1
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
CUL5	1	LRR1	1	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	FBXO11	14	affinity chromatography technology	Abdelmohsen K (2009)	1
COPS6	0	CDKN1B	1	affinity chromatography technology	Choi HH (2015)	1
ELOB	1	CORO7	0	affinity chromatography technology	Watanabe M (2011)	1
RBX1	2	TRIM74	0	two hybrid	Woodsmith J (2012)	1
HIST1H1C	2	CUL4A	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Kim K (2013), Kim K (2013), Kim K (2013), Kim K (2013)	4
RBX1	2	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
CCND1	1	SKP1	0	affinity chromatography technology, affinity chromatography technology	Okabe H (2007), Lin DI (2006)	2
RBX1	2	FBXO18	0	affinity chromatography technology, pull down	Kim J (2002), Kim JH (2004)	2
RFWD2	0	ELOB	1	affinity chromatography technology	Olma MH (2009)	1
BTRC	1	COPS4	0	affinity chromatography technology	Sowa ME (2009)	1
CUL3	17	KCTD17	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Bennett EJ (2010), Ji AX (2016), Kasahara K (2014), Kasahara K (2014), Kasahara K (2014), Pinkas DM (2017)	6
RBX1	2	DAB2IP	3	affinity chromatography technology, affinity chromatography technology	Dai X (2014), Dai X (2014)	2
CUL3	17	IBTK	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Pisano A (2015), Pisano A (2015), Pisano A (2015), Huttlin EL (2017)	5
HAX1	1	RBX1	2	two hybrid	Wang J (2011)	1
FBXO7	1	NEDD8	0	affinity chromatography technology	Teixeira FR (2016)	1
ELAVL1	0	CDKN1B	1	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXW11	2	ELAVL1	0	affinity chromatography technology	Low TY (2014)	1
COPS5	0	FBXO21	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	CUL1	7	affinity chromatography technology	Bennett EJ (2010)	1
UVRAG	2	RBX1	2	affinity chromatography technology	Yang Y (2016)	1
UBE2D2	0	UBE2L3	1	biochemical	Havugimana PC (2012)	1
FBXO2	0	UBE2D1	0	pull down	Nelson RF (2006)	1
COPS3	1	ELOB	1	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Min KW (2005), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	10
RBX1	2	FBXO22	1	affinity chromatography technology	Dias DC (2002)	1
RBX1	2	UBE2M	0	pull down, pull down, pull down, pull down, x-ray crystallography, pull down, pull down, two hybrid, pull down, pull down, pull down, pull down, enzymatic study, pull down	Okuda H (2001), Yoshida Y (2005), Choi YS (2010), Calabrese MF (2011), Calabrese MF (2011), Kim AY (2008), Scott DC (2014), Markson G (2009), Sufan RI (2006), Huang DT (2009), Morimoto M (2003), Ohki Y (2009), Ohki Y (2009), Wang X (2015)	14
FBXO3	0	SKP1	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Shima Y (2008), Yu H (2011), Cloutier P (2017), Hauri S (2016)	4
COPS3	1	FBXO17	1	affinity chromatography technology	Olma MH (2009)	1
RFWD2	0	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
LRR1	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kamura T (2004), Kamura T (2004)	3
SKP2	2	CDC34	3	pull down, enzymatic study, pull down	Cen B (2010), Umanskaya K (2007), Ji P (2006)	3
HIST1H1A	0	RBX1	2	affinity chromatography technology	Kim K (2013)	1
COPS6	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
CUL1	7	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, x-ray crystallography, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Dias DC (2002), Kim J (2002), Zheng N (2002), Kim AY (2008), Ohta T (1999), Ohta T (1999), Ohta T (1999), Bloom J (2006), Block K (2005), Hu J (2004), Hwang JW (2003), Furukawa M (2002), Kawakami T (2001), Ohta T (2001), Chen A (2000), Read MA (2000), Wu K (2000), Tan P (1999), Banerjee S (2010), Gao D (2010), Tron AE (2012), Tron AE (2012), Shteingart S (2012), Tan M (2010), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Huang DT (2004), Emberley ED (2012), Gastaldello S (2012), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Li X (2003), Calabrese MF (2011), Scott DC (2014), Scott DC (2014), Siergiejuk E (2009), Zhou W (2014), Zhou W (2014), Huang DT (2009), Pick E (2007), Morimoto M (2003), Morimoto M (2003), Ohki Y (2009), Duda DM (2008), Duda DM (2008), Wan C (2015), Hao J (2015), Hao J (2015), Han XR (2016), Kuang P (2016), Zhou W (2017), Hu Y (2017), Reitsma JM (2017)	59
ELAVL1	0	ING3	3	affinity chromatography technology	Abdelmohsen K (2009)	1
CREB3L3	1	BTRC	1	pull down, affinity chromatography technology	Barbosa S (2015), Cheng Y (2016)	2
COPS3	1	DTL	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Higa LA (2006)	2
DIO2	0	ELOC	0	affinity chromatography technology	Dentice M (2005)	1
COPS7A	0	BTRC	1	affinity chromatography technology	Huang X (2016)	1
DTL	0	FBXO18	0	affinity chromatography technology	Bacquin A (2013)	1
GRK5	7	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
HINT1	0	RBX1	2	pull down, affinity chromatography technology, affinity chromatography technology	Cen B (2009), Cen B (2009), Cen B (2009)	3
RFWD2	0	CUL1	7	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	VHL	0	affinity chromatography technology	Bemis L (2004)	1
DCUN1D4	0	CUL3	17	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	5
FBXO6	0	COPS7A	0	affinity chromatography technology	Liu B (2012)	1
CDC34	3	FBXW2	0	enzymatic study	Cenciarelli C (1999)	1
UBE2D2	0	TRIM27	2	two hybrid, two hybrid	Markson G (2009), Napolitano LM (2011)	2
KMT5A	2	DDB1	6	affinity chromatography technology	Abbas T (2010)	1
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
DCUN1D1	0	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXW8	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Okabe H (2007), Litterman N (2011), Busino L (2012), Watanabe N (2004), Ponyeam W (2012), Tian X (2015), Xu X (2008), Hauri S (2016)	9
RBX1	2	UBE2G1	2	pull down, pull down, pull down	Chen BB (2012), Zou C (2011), Chen BB (2013)	3
MAP3K20	1	RBX1	2	two hybrid	Vinayagam A (2011)	1
CRBN	2	UBE2D1	0	pull down	Petzold G (2016)	1
UBE2M	0	CUL1	7	enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Huang G (2011), Huang G (2011), Kim AY (2008), Ponyeam W (2012), Ohki Y (2009), Zhou W (2017), Mo Z (2016)	7
CAND1	2	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
RBX1	2	HSPA1A	0	affinity chromatography technology	Dias DC (2002)	1
SUV39H1	0	ESR1	0	enzymatic study	Zhang X (2013)	1
ELAVL1	0	SKP1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
COPS3	1	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
TP53	0	RBX1	2	affinity chromatography technology	Fogeron ML (2013)	1
COPS6	0	FEM1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
CUL3	17	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huang X (2016), Huttlin EL (2017)	5
PSMA6	1	CCNF	2	affinity chromatography technology	Sharma SS (2011)	1
ERCC8	1	UBXN7	3	affinity chromatography technology	He J (2016)	1
COPS3	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Stotland A (2012), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	12
SKP1	0	CCNF	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2007), DAngiolella V (2012), Yoshida Y (2011), Kuchay S (2017), Choudhury R (2017)	5
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
DAB2IP	3	FBXW7	2	affinity chromatography technology	Dai X (2014)	1
CREB3L3	1	CUL1	7	affinity chromatography technology	Cheng Y (2016)	1
RFWD2	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
RIPK4	0	HAX1	1	affinity chromatography technology	Rodriguez J (2016)	1
CUL4A	2	TUBA1B	0	affinity chromatography technology	Dias DC (2002)	1
NEDD8	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
VHL	0	UBE2D2	0	pull down	Xin H (2011)	1
KEAP1	0	KLHL3	1	two hybrid	Rolland T (2014)	1
CUL1	7	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Reitsma JM (2017)	6
ELAVL1	0	KLHL3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ELOB	1	MED8	0	two hybrid, two hybrid, affinity chromatography technology	Brower CS (2002), Brower CS (2002), Brower CS (2002)	3
COPS5	0	KLHL18	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
ING3	3	CUL1	7	affinity chromatography technology, affinity chromatography technology	Chen G (2010), Chen G (2010)	2
CUL4A	2	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009)	7
DDB2	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
MAP3K7	2	COPS5	0	two hybrid	Bandyopadhyay S (2010)	1
SMAD3	1	APP	1	pull down	Olah J (2011)	1
RBX1	2	GFPT1	0	biochemical	Kristensen AR (2012)	1
CUL3	17	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
TRPC4AP	4	RBX1	2	affinity chromatography technology	Choi SH (2010)	1
RBX1	2	RPS6KB1	1	pull down, affinity chromatography technology	Panasyuk G (2008), Panasyuk G (2008)	2
CUL3	17	KLHL18	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Moghe S (2012), Moghe S (2012), Huttlin EL (2017)	5
TP53	0	SKP1	0	affinity chromatography technology	Fogeron ML (2013)	1
KMT5A	2	RBX1	2	affinity chromatography technology	Wang Z (2015)	1
FBXO7	1	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
ELAVL1	0	BTRC	1	affinity chromatography technology, affinity chromatography technology	Chu PC (2012), Chu PC (2012)	2
DIO2	0	RBX1	2	affinity chromatography technology	Dentice M (2005)	1
CUL1	7	ESR1	0	affinity chromatography technology	Zhou W (2014)	1
TP53	0	EEF1A1	0	affinity chromatography technology	Fogeron ML (2013)	1
KLHL7	5	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kigoshi Y (2011), Bennett EJ (2010), Huttlin EL (2017)	3
RBX1	2	UBE2D1	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, unspecified method, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Li Y (2010), Shaik S (2012), Costessi A (2011), Bashir T (2010), Lan L (2012), Welcker M (2011), Wilkins A (2004), Yada M (2004), Li C (2011), Lee DF (2009), Santra MK (2009), Chen BB (2012), Liu J (2002), Duan S (2011), Barbash O (2011), Kamura T (2003), Abbas T (2008), Peschiaroli A (2009), Popov N (2010), Uchida S (2011), Dimitrova YN (2010), Maerki S (2009), Malatesta M (2012), Davis MA (2013), Chen H (2013), Mallampalli RK (2013), Rossi M (2013), Mori Y (2013), Lu A (2013), Fischer ES (2014), Andresen CA (2014), Herrero-Ruiz J (2014), Johansson P (2014), Uchiki T (2009), Min SH (2012), Gao D (2010), Canettieri G (2010), Lin MY (2011), Read MA (2000), Zhang DD (2004), Zhang DD (2005), Fukushima H (2013), Matsumoto S (2015), Ibeawuchi SR (2015), Malonia SK (2015), Liu Y (2015), Liu Y (2015), Gao J (2015), Zhang C (2015), Chu WK (2015), Barbash O (2009), Kershaw NJ (2014), Nam S (2009), Wu HC (2014), Kim JH (2015), Kung YA (2017), Nguyen TV (2016), Shimizu K (2017), Gschweitl M (2016), Terai K (2013), Chandra S (2013), Dai X (2017), Qie S (2017), Chen BB (2013), Kroenke J (2014)	65
DDB1	6	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006), Jin J (2006), Higa LA (2006), Rossi M (2013), Shibata E (2011), Higa LA (2006), Higa LA (2006)	8
RBX1	2	DNMT3A	17	affinity chromatography technology	Yang Y (2015)	1
CUL4B	8	DCUN1D1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016)	8
DDB1	6	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
TP53	0	CSNK1E	0	imaging technique	Chen TC (2014)	1
COPS5	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	FBXL15	0	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012)	4
CUL7	4	CBX5	3	affinity chromatography technology	Hanson D (2014)	1
DCUN1D1	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
SMAD3	1	CUL1	7	affinity chromatography technology	Ray D (2005)	1
RIPK4	0	SAMHD1	3	affinity chromatography technology	Rodriguez J (2016)	1
ESR1	0	CUL3	17	affinity chromatography technology	Byun B (2008)	1
DAB2IP	3	CUL1	7	affinity chromatography technology	Dai X (2014)	1
TP53	0	HSPA8	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Akakura S (2001), Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994), Karras GI (2017)	7
CUL1	7	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chua YS (2011), Chua YS (2011), Tron AE (2012), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Liu J (2002), Huttlin EL (2017)	8
FBXO6	0	ACTG1	5	affinity chromatography technology	Liu B (2012)	1
CRBN	2	DDA1	1	affinity chromatography technology	Kroenke J (2014)	1
DCUN1D1	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	CUL5	1	enzymatic study	Duda DM (2008)	1
FBXW7	2	EZH2	4	affinity chromatography technology, affinity chromatography technology, pull down	Jin X (2017), Jin X (2017), Jin X (2017)	3
TP53	0	CUL9	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nikolaev AY (2003), Nikolaev AY (2003), Nikolaev AY (2003), Nikolaev AY (2003), Nikolaev AY (2003), Becker K (2007), Dowell JD (2007), Pei XH (2011), Skaar JR (2007), Skaar JR (2007), Skaar JR (2007), Vitali R (2008), Vitali R (2008), Kasper JS (2006), Fogeron ML (2013), Huttlin EL (2015), Li X (2015), Huttlin EL (2017)	18
KMT5A	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wang Z (2015), Wang Z (2015), Wang Z (2015), Wang Z (2015), Wang Z (2015)	5
CUL4B	8	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Bennett EJ (2010), Bennett EJ (2010), Hein MY (2015)	6
DDB1	6	GPS1	1	affinity chromatography technology, pull down, fluorescent resonance energy transfe	Jin J (2006), Emberley ED (2012), Cavadini S (2016)	3
NEDD4	2	UBE2D1	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Vina-Vilaseca A (2010), Sehat B (2008), Platta HW (2012), Tofaris GK (2011), Uchiki T (2009), Liu PY (2012), Sugeno N (2014), Kim HT (2007), Chen Z (2016)	9
CDKN1B	1	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Guidoboni M (2005), Vlach J (1996), Vlach J (1997), Tsai CH (2009), Ciarallo S (2002), Bindra RS (2002), Kossatz U (2006), Grimmler M (2007), Rolland T (2014), Hein MY (2015), Barbash O (2009), Huttlin EL (2017)	13
UBE2D2	0	FBXO7	1	enzymatic study, pull down	Cenciarelli C (1999), Teixeira FR (2016)	2
MAP3K7	2	CRBN	2	affinity chromatography technology, affinity chromatography technology	Min Y (2016), Min Y (2016)	2
DDB1	6	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Jamal A (2015), Huttlin EL (2017)	4
UBE2D2	0	BTRC	1	enzymatic study	Cenciarelli C (1999)	1
GATA2	0	PML	7	two hybrid, affinity chromatography technology, pull down	Tsuzuki S (2000), Tsuzuki S (2000), Tsuzuki S (2000)	3
SESN1	2	KEAP1	0	affinity chromatography technology	Bae SH (2013)	1
CUL7	4	FBXW7	2	affinity chromatography technology, affinity chromatography technology	Arai T (2003), Arai T (2003)	2
COPS5	0	HIST1H4A	0	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
EEF1A1	0	ABTB2	2	pull down, affinity chromatography technology, affinity chromatography technology	Koiwai K (2008), Koiwai K (2008), Koiwai K (2008)	3
MCM10	2	CUL4A	2	affinity chromatography technology	Kaur M (2012)	1
TP53	0	DAB2IP	3	affinity chromatography technology	Lunardi A (2010)	1
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
DCUN1D5	0	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
COPS5	0	PGAM5	4	affinity chromatography technology	Bennett EJ (2010)	1
MYB	3	DDB1	6	affinity chromatography technology	Kanei-Ishii C (2012)	1
DCUN1D4	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
UBXN1	0	DDB1	6	affinity chromatography technology	Alexandru G (2008)	1
CUL1	7	DCAF1	5	affinity chromatography technology	McCall CM (2008)	1
CUL4B	8	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Higa LA (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	9
PSMA2	1	FBXW7	2	affinity chromatography technology	Bousquet-Dubouch MP (2009)	1
CAND1	2	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
DCUN1D3	1	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
HIF1A	1	OS9	4	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Baek JH (2005), Baek JH (2005), Baek JH (2005), Yanagisawa K (2010)	4
VHL	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Kohroki J (2005), Kamura T (2002), Kuznetsova AV (2003), Norman JA (2006), Knauth K (2006), Kamura T (2004), Heir P (2013), Essers PB (2014), Lee SB (2016)	10
FBXL5	3	RBX1	2	affinity chromatography technology, biochemical	Salahudeen AA (2009), Vinas-Castells R (2013)	2
GPS1	1	IP6K1	5	pull down	Rao F (2014)	1
MAP4K1	1	MAP3K7	2	affinity chromatography technology	Zhou G (1999)	1
ERCC8	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
CASP3	0	APP	1	imaging technique	Chen TC (2014)	1
DCUN1D3	1	CUL4B	8	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
CUL4A	2	FBXW8	2	affinity chromatography technology	He YJ (2006)	1
VHL	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Kamura T (2001), Hacker KE (2008), Hacker KE (2008), Menon S (2008), Chew EH (2007), Ietta F (2006), Megumi Y (2005), Kamura T (2002), Kuznetsova AV (2003), Hansen WJ (2002), Cockman ME (2000), Lisztwan J (1999), Lisztwan J (1999), Sufan RI (2006), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Knauth K (2006), Lonergan KM (1998), Lai Y (2012), Miller F (2005), Mahrour N (2008), Grosfeld A (2007), Russell RC (2011), Foxler DE (2012), Bonicalzi ME (2001), Bennett EJ (2010), Kanaya K (2002), Liakopoulos D (1999), Pause A (1997), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Pause A (1999), Pause A (1999), Xin H (2011), Kamura T (2004), Kamura T (2004), Heir P (2013), Russell RC (2008), Russell RC (2008), Essers PB (2014), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Heir P (2016), Chen K (2016), Uematsu K (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	54
UBE2D1	0	RNF126	2	two hybrid, two hybrid, two hybrid	Rual JF (2005), Markson G (2009), Rolland T (2014)	3
NEDD8	0	FBXO3	0	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	DCUN1D3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
KLHL3	1	RBX1	2	affinity chromatography technology	Ohta A (2013)	1
COPS5	0	FBXW11	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	LRR1	1	affinity chromatography technology	Wimuttisuk W (2014)	1
MED8	0	APP	1	pull down	Olah J (2011)	1
CUL3	17	HIST1H4A	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXO25	1	CAND1	2	affinity chromatography technology, affinity chromatography technology	Teixeira FR (2010), Teixeira FR (2010)	2
DCUN1D1	0	CUL5	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
DCUN1D1	0	COPS5	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D5	0	CUL4B	8	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
COPS6	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Olma MH (2009)	5
HIF1A	1	SMAD3	1	imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sanchez-Elsner T (2001), Sanchez-Elsner T (2001), Sanchez-Elsner T (2001), Sanchez-Elsner T (2001), Sanchez-Elsner T (2002)	5
CUL3	17	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
FBXO32	2	UBE2D3	1	pull down	Lokireddy S (2011)	1
CUL2	3	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
UBXN7	3	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	4
CUL2	3	MED8	0	affinity chromatography technology	Brower CS (2002)	1
COPS6	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Enchev RI (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
VHL	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, far western blotting, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, protein complementation assay, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Corn PG (2003), Li Z (2003), Mahon PC (2001), Tanimoto K (2000), Min JH (2002), Yu F (2001), Yu F (2001), Jung JE (2008), Jung JE (2008), Andre H (2008), Park YK (2008), Kim BY (2008), Park SS (2008), Baek JH (2007), Baek JH (2007), Baek JH (2007), Kondo S (2006), Ietta F (2006), Kwon SJ (2005), Bae MK (2005), Baek JH (2005), Hon WC (2002), Hon WC (2002), Lewis MD (2004), Kasuno K (2004), Metzen E (2003), Metzen E (2003), Zhou J (2003), Yuan Y (2003), Maynard MA (2003), Jeong JW (2002), Yoo YG (2008), Hansen WJ (2002), Masson N (2001), Masson N (2001), Clifford SC (2001), Jaakkola P (2001), Jaakkola P (2001), Kamura T (2000), Kamura T (2000), Kamura T (2000), Ohh M (2000), Ohh M (2000), Cockman ME (2000), Cockman ME (2000), Sufan RI (2006), Chang CC (2011), Sufan RI (2009), Stickle NH (2004), Luo W (2010), Lee HY (2011), Roe JS (2011), Ivan M (2001), Ivan M (2001), Huang LE (2002), Callapina M (2005), Callapina M (2005), Maranchie JK (2002), DAngelo G (2003), DAngelo G (2003), Miller F (2005), Grosfeld A (2007), Grosfeld A (2007), Rajakumar A (2008), Bonicalzi ME (2001), Bemis L (2004), Berra E (2001), Yu F (2001), Bex C (2007), Zhou J (2012), Wiesener MS (2002), Maxwell PH (1999), Maxwell PH (1999), Lee SH (2012), Lee SH (2012), Ivan M (2002), Aprelikova O (2009), Choi CY (2009), Choi CY (2009), Heir P (2013), Russell RC (2008), Russell RC (2008), Park JH (2011), Park JH (2011), Liu Q (2013), Yeh IJ (2013), Choi YK (2010), Yang F (2014), Yang F (2014), Yang F (2014), Parsanejad M (2014), Yang C (2013), Yang C (2013), Chen K (2013), Park MH (2014), Gerez J (2015), Hein MY (2015), Park MH (2015), Fu R (2016), Alahari S (2015), Zhang CS (2015), Song D (2013), Chen K (2016), Hicks KC (2016), Groulx I (2002), Groulx I (2002), Groulx I (2002), Huttlin EL (2017), Guo J (2016), Sun W (2017), Sun W (2017), Guo J (2016), Li YM (2005), Yoo YG (2004), Kimura M (2008), Ferrer CM (2014)	116
TRPC4AP	4	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
KLHL7	5	RBX1	2	affinity chromatography technology	Kigoshi Y (2011)	1
CUL2	3	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
DDA1	1	CAND1	2	affinity chromatography technology	Behrends C (2010)	1
DIO2	0	CUL5	1	affinity chromatography technology	Dentice M (2005)	1
RBX1	2	ACTG1	5	affinity chromatography technology	Dias DC (2002)	1
FBXW11	2	UBE2R2	2	affinity chromatography technology, affinity chromatography technology	Coyaud E (2015), Low TY (2014)	2
UBXN7	3	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	4
COPS5	0	FBXO7	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
RBX1	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, bioid	Tan M (2010), Oshikawa K (2003), Coyaud E (2015)	3
TP53	0	FBXO11	14	affinity chromatography technology, pull down, affinity chromatography technology	Abida WM (2007), Abida WM (2007), Abida WM (2007)	3
GRK5	7	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
KMT5A	2	SKP1	0	affinity chromatography technology	Wang Z (2015)	1
FBXO6	0	TUBA1B	0	affinity chromatography technology	Liu B (2012)	1
MYB	3	FBXW7	2	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kanei-Ishii C (2008), Kanei-Ishii C (2008), Kitagawa K (2010), Kitagawa K (2010)	4
TAB1	1	TRPC4AP	4	two hybrid	Vinayagam A (2011)	1
DCUN1D5	0	CUL3	17	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	7
FEM1B	1	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mahrour N (2008), Bennett EJ (2010), Huttlin EL (2017)	3
IBTK	3	COPS3	1	affinity chromatography technology	Pisano A (2015)	1
FBXW2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Saiga T (2009), Xu J (2017)	2
KCTD17	0	UBE2D1	0	pull down	Kasahara K (2014)	1
RICTOR	4	TUBA1B	0	affinity chromatography technology	Pearce LR (2007)	1
RAG1	1	UBE2D1	0	pull down	Singh SK (2015)	1
FBXO2	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wen H (2010), Glenn KA (2008), Jeong YT (2013), Reitsma JM (2017)	4
RIPK4	0	HSPA8	4	affinity chromatography technology	Rodriguez J (2016)	1
ESR1	0	FBXO18	0	pull down	Nalvarte I (2010)	1
LRRC14	2	ELOB	1	affinity chromatography technology	Olma MH (2009)	1
COPS6	0	ELOB	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
PGAM5	4	RBX1	2	affinity chromatography technology	Lo SC (2006)	1
DDB1	6	COPS4	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Olma MH (2009)	4
CUL3	17	ELOC	0	affinity chromatography technology, two hybrid	Bennett EJ (2010), Wang J (2011)	2
COPS6	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	6
CUL1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
COPS6	0	FBXO17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
COPS5	0	TRPC4AP	4	affinity chromatography technology	Bennett EJ (2010)	1
FBXO25	1	ING3	3	enzymatic study	Teixeira FR (2013)	1
COPS3	1	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
DCUN1D1	0	CUL2	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Monda JK (2013), Heir P (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Chen K (2016)	13
KMT5A	2	TP53	0	enzymatic study	Shi X (2007)	1
HIST1H4A	0	RBX1	2	biochemical	Kristensen AR (2012)	1
SKP2	2	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
UBE2E2	1	DDA1	1	affinity chromatography technology	Pick E (2007)	1
UBE2M	0	TP53	0	enzymatic study	Xirodimas DP (2004)	1
EZH2	4	DNMT3A	17	pull down, affinity chromatography technology, affinity chromatography technology	Vire E (2006), Vire E (2006), Vire E (2006)	3
SKP2	2	UBE2L3	1	affinity chromatography technology	Ma X (2017)	1
GATA2	0	FBXW7	2	affinity chromatography technology, affinity chromatography technology, pull down	Nakajima T (2015), Nakajima T (2015), Nakajima T (2015)	3
CUL1	7	FBXL12	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kim M (2008), Postow L (2013), Nishiyama M (2015), Reitsma JM (2017)	5
UBE2R2	2	UBE2D2	0	biochemical	Wan C (2015)	1
CUL7	4	GLMN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Arai T (2003), Arai T (2003), Huttlin EL (2017)	3
COPS5	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kroenke J (2014)	2
TRIM27	2	UBE2E3	0	two hybrid, two hybrid	Napolitano LM (2011), Napolitano LM (2011)	2
ELAVL1	0	SKP2	2	affinity chromatography technology	Abdelmohsen K (2009)	1
LRR1	1	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
ELAVL1	0	HIF1A	1	affinity chromatography technology, unspecified method	Galban S (2008), Galban S (2008)	2
CUL5	1	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	MKNK2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ELAVL1	0	CSNK1E	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CDKN1B	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miranda-Carboni GA (2008), Bondar T (2006), Li B (2006), Li B (2006), Gao J (2015)	5
DDB1	6	DNMT3A	17	affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015)	2
UBE2R2	2	BTRC	1	pull down, affinity chromatography technology, bioid	Semplici F (2002), Coyaud E (2015), Coyaud E (2015)	3
FBXW11	2	RBX1	2	affinity chromatography technology	Tan P (1999)	1
VHL	0	CDC34	3	pull down	Masson N (2001)	1
CUL5	1	HIST1H4A	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	ELOB	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kamura T (2001), Menon S (2008), Megumi Y (2005), Kamura T (2002), Brower CS (2002), Bennett EJ (2010), Pause A (1997), Kamura T (2004), Kelsall IR (2013)	9
BTRC	1	NEDD4	2	affinity chromatography technology, affinity chromatography technology	Liu J (2014), Liu J (2014)	2
RNF126	2	GFPT1	0	affinity chromatography technology	OConnor HF (2015)	1
COPS6	0	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
VHL	0	HSPA8	4	affinity chromatography technology, pull down	Lai Y (2011), Lai Y (2012)	2
GRK5	7	EEF1A1	0	affinity chromatography technology	Wu Z (2012)	1
FBXW8	2	CCND1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology	Okabe H (2007), Okabe H (2007), Wei S (2008)	3
CUL5	1	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	RFWD2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXL12	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim M (2008), Postow L (2013), Postow L (2013), Nishiyama M (2015), Hauri S (2016)	5
DCUN1D3	1	ELOB	1	affinity chromatography technology	Keuss MJ (2016)	1
SAMHD1	3	APP	1	pull down	Olah J (2011)	1
CUL4B	8	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Yang Y (2015)	4
COPS5	0	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	COPS7A	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015), Hein MY (2015), Huang X (2016)	6
DDB1	6	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009), He F (2013)	6
DDB2	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Hein MY (2015)	6
DCUN1D2	0	CUL4A	2	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
DDB1	6	CRBN	2	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology	Angers S (2006), Ito T (2010), Chamberlain PP (2014), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Matyskiela ME (2018), Kroenke J (2014)	12
DDB1	6	SUV39H1	0	affinity chromatography technology, pull down	Yang Y (2015), Yang Y (2015)	2
FBXO31	4	RBX1	2	affinity chromatography technology, affinity chromatography technology	Kumar R (2005), Jeffery JM (2017)	2
CUL4B	8	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Olma MH (2009)	2
COPS4	0	ELOC	0	affinity chromatography technology	Olma MH (2009)	1
CAND1	2	UBE2M	0	pull down	Kim AY (2008)	1
CUL2	3	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
NEDD4	2	UBE2D2	0	two hybrid, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Hatakeyama S (1997), Anan T (1998), Sehat B (2008), Arevalo JC (2006), Woelk T (2006), Persaud A (2009), Zeng F (2009), Sarkari F (2013), Liu PY (2012), Sugeno N (2014), Bustos F (2015), Chesarino NM (2015), Sun M (2016)	13
PSMA6	1	COPS5	0	affinity chromatography technology	Huang X (2005)	1
CDC34	3	CUL1	7	pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology	Block K (2005), Wirbelauer C (2000), Saha A (2008), Sandoval D (2014), Wu K (2016)	5
RAG1	1	UBE2D2	0	pull down, pull down, pull down	Grazini U (2010), Yurchenko V (2003), Singh SK (2015)	3
APP	1	RAG1	1	pull down	Virok DP (2011)	1
KMT5A	2	HIST1H4A	0	enzymatic study, enzymatic study, x-ray crystallography, x-ray crystallography, unspecified method, x-ray crystallography	Fang J (2002), Yin Y (2005), Couture JF (2005), Xiao B (2005), Xiao B (2005), Zhang X (2008)	6
RIPK4	0	CAND1	2	affinity chromatography technology	Rodriguez J (2016)	1
AHR	3	NEDD8	0	pull down, affinity chromatography technology	Antenos M (2002), Antenos M (2002)	2
DET1	2	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	CUL7	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Andrews P (2006), Andrews P (2006), Andrews P (2006), Dowell JD (2007), Dowell JD (2007), Dowell JD (2007), Skaar JR (2007), Skaar JR (2007), Kim SS (2007), Kim SS (2007), Kim SS (2007), Kaustov L (2007), Kasper JS (2006), Kasper JS (2006), Kasper JS (2006), Fogeron ML (2013), Hanson D (2014), Hanson D (2014), Huttlin EL (2015), Li X (2015), Huttlin EL (2017), Guo H (2014)	22
PSMA6	1	CCND1	1	affinity chromatography technology	Sharma SS (2011)	1
DCUN1D1	0	CUL3	17	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Bommelje CC (2013), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Huang G (2014), Huang G (2014), Monda JK (2013), Wan C (2015), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Huttlin EL (2017)	19
FBXO7	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Kirk R (2008), Hsu JM (2004), Hagens O (2006), Bennett EJ (2010), Hein MY (2015), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Reitsma JM (2017), Reitsma JM (2017)	11
UBE2L3	1	NEDD4	2	enzymatic study, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Anan T (1998), Bruce MC (2008), Wiesner S (2007), Vina-Vilaseca A (2010), Anindya R (2007), Lin Q (2010), Chung S (2011), Tofaris GK (2011), Han L (2013), Persaud A (2014), Uchiki T (2009), Miyazaki K (2003), Zhang W (2016), Zhang X (2017)	14
SAMHD1	3	DDB1	6	affinity chromatography technology	Ahn J (2012)	1
CUL2	3	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	GFPT1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL2	3	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Kamura T (2004), Kamura T (2004), Kamura T (2004)	5
RBX1	2	SERTAD1	0	two hybrid	Wang J (2011)	1
RIPK4	0	ERBIN	5	affinity chromatography technology	Rodriguez J (2016)	1
CDKN1B	1	VHL	0	genetic interference	Shen JP (2017)	1
COPS5	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Fang L (2008), Enchev RI (2010), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Asare Y (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	13
TP53	0	PTGS2	0	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	King JG (2001), Choi EM (2009), Choi EM (2009), Choi EM (2009), Tang HY (2006), Tang HY (2006), Lin C (2011), Lin C (2011), Choi EM (2005), Choi EM (2005), Choi EM (2005), Choi EM (2005)	12
HSPA8	4	TAB1	1	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	FBXW8	2	affinity chromatography technology	Li X (2015)	1
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
RBX1	2	RNF126	2	two hybrid	Woodsmith J (2012)	1
DCUN1D2	0	CUL4B	8	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016)	4
DDB2	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Hein MY (2015)	4
UBXN1	0	RBX1	2	affinity chromatography technology	Hu Y (2017)	1
ELAVL1	0	DCUN1D4	0	affinity chromatography technology	Abdelmohsen K (2009)	1
FBXW11	2	COPS7A	0	affinity chromatography technology	Kim TY (2014)	1
TP53	0	DCAF1	5	pull down	Kim K (2012)	1
CSNK1E	0	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
UBXN7	3	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bandau S (2012)	2
ESR1	0	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Dhamad AE (2016), Dhamad AE (2016)	2
COPS6	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
CUL2	3	HIST1H4A	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	FEM1B	1	affinity chromatography technology	Olma MH (2009)	1
RBX1	2	TUBA1B	0	affinity chromatography technology	Dias DC (2002)	1
RFWD2	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Choi HH (2011), Choi HH (2011)	4
ING3	3	RBX1	2	affinity chromatography technology, affinity chromatography technology	Chen G (2010), Chen G (2010)	2
FBXO32	2	RBX1	2	affinity chromatography technology	Al-Yacoub N (2016)	1
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
DCUN1D4	0	RBX1	2	affinity chromatography technology	Keuss MJ (2016)	1
FEM1B	1	RBX1	2	affinity chromatography technology	Kamura T (2004)	1
TRIM27	2	PML	7	affinity chromatography technology	Cao T (1998)	1
PRAME	2	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Costessi A (2011), Costessi A (2011), Costessi A (2012), Costessi A (2012), Wadelin FR (2013), Wadelin FR (2013), Costessi A (2011)	7
SKP1	0	FBXO2	0	x-ray crystallography, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, two hybrid, affinity chromatography technology	Mizushima T (2007), Lievens S (2009), Nelson RF (2007), Henzl MT (2004), Henzl MT (2004), Glenn KA (2008), Tan A (2008), Erhardt JA (1998), Winston JT (1999), Rolland T (2014), Hauri S (2016)	11
DDA1	1	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
CCND1	1	ESR1	0	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Zwijsen RM (1997), Zwijsen RM (1997), Zwijsen RM (1997), Wang C (2005), Wang C (2005)	5
UBE2E2	1	CUL3	17	pull down	Plafker KS (2009)	1
RBX1	2	RBX1	2	enzymatic study	Morimoto M (2003)	1
CUL4B	8	SUV39H1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015), Yang Y (2015)	5
GHR	1	SKP1	0	affinity chromatography technology, unspecified method	da Silva Almeida AC (2013), Bulatov E (2015)	2
NEDD4	2	UBE2M	0	pull down	Persaud A (2009)	1
CUL3	17	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXW8	2	CUL2	3	affinity chromatography technology	Litterman N (2011)	1
OS9	4	RBX1	2	two hybrid	Wang J (2011)	1
UBXN7	3	DDB1	6	affinity chromatography technology	Alexandru G (2008)	1
CASP1	1	RBX1	2	affinity chromatography technology	Garstkiewicz M (2017)	1
FBXW8	2	FBXW2	0	affinity chromatography technology	Ponyeam W (2012)	1
DCUN1D2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Keuss MJ (2016), Keuss MJ (2016)	2
DCAF1	5	UBE2D2	0	pull down	Ahn J (2010)	1
HIST1H1A	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCUN1D1	0	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Keuss MJ (2016)	2
UBE2D3	1	NEDD4	2	enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down	Anan T (1998), Wang X (2008), Maspero E (2011), Katz M (2002), Wu K (2011), Maspero E (2013), Hong SW (2013), Zhou W (2014), Sugeno N (2014), Maspero E (2013), Miyazaki K (2003), Mari S (2014), Song F (2013), Fan CD (2013)	14
UBE2L3	1	UBXN7	3	biochemical	Havugimana PC (2012)	1
BTRC	1	ERBIN	5	bioid, affinity chromatography technology, affinity chromatography technology	Coyaud E (2015), Xie CM (2015), Xie CM (2015)	3
DIO2	0	UBE2G1	2	fluorescent resonance energy transfe, pull down	Sagar GD (2007), Kim BW (2003)	2
GLMN	2	DTL	0	affinity chromatography technology	Huttlin EL (2017)	1
FBXO31	4	CCND1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Santra MK (2009), Santra MK (2009), Santra MK (2009), Yumimoto K (2013), Johansson P (2014)	5
PSMA2	1	HSPA8	4	affinity chromatography technology	Bousquet-Dubouch MP (2009)	1
COPS5	0	SKP2	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
ELOB	1	FEM1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mahrour N (2008), Mahrour N (2008), Kamura T (2004)	3
DDB1	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Jin J (2006), Groisman R (2003), Groisman R (2003), Meulenbroek EM (2012), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Chitale S (2017), Ohtake F (2007)	10
COPS5	0	FBXO17	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
DCUN1D1	0	NEDD8	0	affinity chromatography technology	Bennett EJ (2010)	1
ARID1B	80	CUL2	3	affinity chromatography technology, affinity chromatography technology, pull down	Li XS (2010), Li XS (2010), Li XS (2010)	3
CUL3	17	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Higa LA (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Lu G (2014)	7
COPS5	0	KBTBD6	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	ELOB	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
FBXW7	2	TUBA1B	0	genetic interference	Bailey ML (2015)	1
CUL3	17	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	KLHL18	2	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	ABTB2	2	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	UBE2M	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li T (2006), Norman JA (2006), Huttlin EL (2017)	3
CUL1	7	GHR	1	unspecified method	Bulatov E (2015)	1
CCND2	2	HSPB1	2	affinity chromatography technology	Russo LC (2017)	1
RBX1	2	RICTOR	4	affinity chromatography technology, affinity chromatography technology	Gao D (2010), Gao D (2010)	2
FBXO31	4	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kumar R (2005), Bennett EJ (2010), Vadhvani M (2013), Jeong YT (2013), Hein MY (2015), Malonia SK (2015), Jeffery JM (2017), Reitsma JM (2017)	8
ERCC8	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
SAMHD1	3	CUL4A	2	affinity chromatography technology	Morrissey C (2015)	1
DTL	0	RBX1	2	affinity chromatography technology	Shibata E (2011)	1
CDKN1B	1	DDB1	6	affinity chromatography technology	Iovine B (2011)	1
FBXW8	2	SKP2	2	affinity chromatography technology	Ponyeam W (2012)	1
DCAF1	5	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Hrecka K (2007), Olma MH (2009)	3
CUL1	7	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	FBXO21	2	affinity chromatography technology	Abdelmohsen K (2009)	1
CRBN	2	SUV39H1	0	two hybrid	Weimann M (2013)	1
HIF1A	1	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Chen D (2003), Ravi R (2000), Hansson LO (2002), An WG (1998), An WG (1998), Chowdhury AR (2017), Chowdhury AR (2017), Suzuki H (2001), Sanchez-Puig N (2005)	9
CUL1	7	FBXL15	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Cui Y (2011), Huttlin EL (2015), Huttlin EL (2017), Reitsma JM (2017)	5
DCUN1D3	1	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Huang G (2014), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	6
RBX1	2	UBE2G2	0	pull down, pull down	Mallampalli RK (2013), Zou C (2011)	2
FBXO17	1	RBX1	2	affinity chromatography technology	Glenn KA (2008)	1
CUL3	17	FXR1	0	affinity chromatography technology	Bennett EJ (2010)	1
DDA1	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
FBXO44	0	DDB1	6	affinity chromatography technology	Sjoegren B (2015)	1
RBX1	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Norman JA (2006)	2
UBXN1	0	KBTBD7	3	affinity chromatography technology	Alexandru G (2008)	1
SKP1	0	UBE2D1	0	pull down, pull down	Kamura T (2000), Lin DI (2006)	2
COPS6	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	12
COPS6	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009)	5
CUL7	4	FXR1	0	affinity chromatography technology	Hanson D (2014)	1
FBXW7	2	CUL1	7	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu G (2001), Tron AE (2012), Busino L (2012), Busino L (2012), Busino L (2012), Matsumoto A (2011), Bennett EJ (2010), Strohmaier H (2001), Davis MA (2013), JunGang Z (2012), Busino L (2003), Pierce NW (2013), Chung FZ (2014), Yumimoto K (2012), Low TY (2014), Kourtis N (2015), Gorelik M (2016), Gorelik M (2016), Huttlin EL (2017), Reiterer V (2017), Reiterer V (2017), Ye M (2017), Reitsma JM (2017)	23
COPS6	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Sharon M (2009), Bennett EJ (2010), Lingaraju GM (2014), Huttlin EL (2015), Huttlin EL (2017)	7
HSPA1A	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994)	5
DCUN1D5	0	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
PTGS2	0	APP	1	affinity chromatography technology, affinity chromatography technology	Nagano S (2004), Nagano S (2004)	2
FBXO21	2	RBX1	2	affinity chromatography technology	Watanabe K (2015)	1
FBXL12	1	RBX1	2	affinity chromatography technology	Kim M (2008)	1
CUL2	3	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Menon S (2008), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012)	7
ESR1	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Ambrosino C (2010), Tarallo R (2011), Gebauer M (1998), Dhamad AE (2016), Dhamad AE (2016)	7
CRBN	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito T (2010), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Kroenke J (2014)	5
COPS6	0	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
ELAVL1	0	CASP3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
DCUN1D2	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
DDA1	1	DTL	0	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
CCND2	2	CDKN1B	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Huttlin EL (2015), Huttlin EL (2017)	3
UBXN1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008)	2
KLHL41	2	RBX1	2	affinity chromatography technology	Zhang DD (2005)	1
TRPC4AP	4	DDA1	1	affinity chromatography technology, affinity chromatography technology	Choi SH (2010), Huttlin EL (2017)	2
GLMN	2	FEM1B	1	affinity chromatography technology	Huttlin EL (2017)	1
NEDD8	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
HIF1A	1	ELOB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Luo W (2010), Heir P (2013), Russell RC (2008)	3
HIST1H4A	0	GFPT1	0	biochemical	Kristensen AR (2012)	1
BTRC	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Xia Y (2009), Verma S (2011)	2
DDA1	1	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
RHOBTB3	1	RBX1	2	affinity chromatography technology, pull down	Lu A (2013), Lu A (2013)	2
PTGS2	0	COPS3	1	affinity chromatography technology	Neuss H (2007)	1
MAP4K1	1	FBXW8	2	affinity chromatography technology, affinity chromatography technology	Wang H (2014), Wang H (2014)	2
CUL2	3	ELOC	0	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Kamura T (2001), Maine GN (2007), Megumi Y (2005), Mao X (2009), Lonergan KM (1998), Lonergan KM (1998), Bennett EJ (2010), Pause A (1997), Pause A (1999), Kamura T (2004), Kelsall IR (2013), Lee SB (2016)	12
DDA1	1	DDB2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Hein MY (2015)	2
HIST1H1C	2	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
UBE2M	0	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
CCND2	2	HIST1H1A	0	enzymatic study, enzymatic study	Sweeney KJ (1997), Jiang W (1998)	2
KDM2B	11	UBE2D1	0	enzymatic study	Janzer A (2012)	1
NEDD4	2	RPS6KB1	1	enzymatic study	Persaud A (2009)	1
DAB2IP	3	CUL4A	2	affinity chromatography technology	Dai X (2014)	1
CUL4B	8	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei J (2012), Hein MY (2015)	3
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
DCUN1D1	0	UBE2M	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, unspecified method, affinity chromatography technology	Kim AY (2008), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Scott DC (2011), Huang G (2014), Huang G (2014), Keuss MJ (2016), Huttlin EL (2017), Zhou H (2017), Zhou H (2017), Zhou H (2017)	13
ELAVL1	0	GATA2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
EEF1A1	0	PSMA6	1	biochemical	Havugimana PC (2012)	1
HIST1H1A	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
UBE2M	0	KBTBD7	3	affinity chromatography technology	Huttlin EL (2017)	1
SKP2	2	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Roe JS (2011), Roe JS (2011), Roe JS (2011)	3
CUL3	17	ERBIN	5	affinity chromatography technology	Wimuttisuk W (2014)	1
RHOB	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Xu J (2015), Xu J (2015)	2
CUL5	1	VHL	0	pull down	Kamura T (2001)	1
CAND1	2	ARID1B	80	affinity chromatography technology	Bennett EJ (2010)	1
PSMA2	1	RBX1	2	affinity chromatography technology	Bousquet-Dubouch MP (2009)	1
BTRC	1	HINT1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Shi Z (2016), Shi Z (2016), Shi Z (2016)	3
FBXW2	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Xu J (2017), Xu J (2017), Xu J (2017)	3
ZC3HC1	1	SKP1	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bassermann F (2007), Bassermann F (2005), Bassermann F (2005), Bassermann F (2005), von Klitzing C (2011), Liu YQ (2015), Liu YQ (2015)	7
TRIM27	2	RBX1	2	two hybrid	Woodsmith J (2012)	1
GLMN	2	CRBN	2	affinity chromatography technology	Huttlin EL (2017)	1
RBX1	2	SUV39H1	0	affinity chromatography technology	Yang Y (2015)	1
ELAVL1	0	CCND1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
GHR	1	FBXW11	2	biochemical	Sedek M (2014)	1
CSNK1E	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
COPS4	0	ELOB	1	affinity chromatography technology	Olma MH (2009)	1
VHL	0	UBE2D1	0	pull down	Gao C (2010)	1
KBTBD7	3	RBX1	2	affinity chromatography technology	Genau HM (2015)	1
RFWD2	0	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Jin J (2006), He YJ (2006), Olma MH (2009), Lu G (2014), Lu G (2014)	6
APP	1	KEAP1	0	affinity chromatography technology	Huttlin EL (2017)	1
MCM10	2	RBX1	2	affinity chromatography technology	Kaur M (2012)	1
CUL3	17	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Angers S (2006), Bennett EJ (2010), Bennett EJ (2010), Sertic S (2013)	5
LRR1	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
DCUN1D2	0	CUL3	17	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	7
UVRAG	2	DDB2	1	affinity chromatography technology	Yang Y (2016)	1
MAPK8IP2	5	VRK2	1	pull down	Blanco S (2008)	1
CUL3	17	UBE2D1	0	pull down	Sumara I (2007)	1
MKNK2	1	VHL	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Wang P (2006), Wang P (2006), Wang P (2006)	3
DDB1	6	ESR1	0	affinity chromatography technology	Ohtake F (2007)	1
HSPB1	2	EEF1A1	0	biochemical	Wan C (2015)	1
FXR1	0	RBX1	2	affinity chromatography technology	Qie S (2017)	1
RFWD2	0	COPS5	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
FBXW7	2	MED8	0	affinity chromatography technology, affinity chromatography technology	Davis MA (2013), Kourtis N (2015)	2
DDB2	1	ERCC8	1	affinity chromatography technology	Groisman R (2003)	1
PSMA6	1	RBX1	2	affinity chromatography technology	Bloom J (2006)	1
FBXO7	1	SKP1	0	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Hsu JM (2004), Nelson DE (2011), Hagens O (2006), Kang J (2014), Winston JT (1999), Hein MY (2015), Hein MY (2015), Vingill S (2016), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Teixeira FR (2016), Hauri S (2016)	16
COPS5	0	MAP4K1	1	affinity chromatography technology	Bennett EJ (2010)	1
DTL	0	TP53	0	affinity chromatography technology, enzymatic study	Banks D (2006), Banks D (2006)	2
COPS4	0	COPS7A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sharon M (2009), Luke-Glaser S (2007), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016)	13
FEM1B	1	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Subauste MC (2009), Mahrour N (2008), Mahrour N (2008), Kamura T (2004)	4
EZH2	4	SUV39H1	0	affinity chromatography technology, two hybrid	Weimann M (2013), Weimann M (2013)	2
FBXW7	2	RAG1	1	genetic interference	Bailey ML (2015)	1
DDB1	6	BTRC	1	affinity chromatography technology	He YJ (2006)	1
ZC3HC1	1	RBX1	2	affinity chromatography technology	Bassermann F (2005)	1
COPS3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	5
CRBN	2	GPS1	1	affinity chromatography technology	Kroenke J (2014)	1
CDC34	3	CDKN1B	1	enzymatic study, unspecified method	Ryu KS (2008), Duda DM (2012)	2
HSPB1	2	MAP3K7	2	affinity chromatography technology	Qi Z (2014)	1
GPS1	1	COPS4	0	affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical	Stotland A (2012), Tsuge T (2001), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015)	7
NEDD4	2	FBXL15	0	affinity chromatography technology	Cui Y (2011)	1
CDKN1B	1	HIST1H1A	0	enzymatic study	Ciarallo S (2002)	1
GAN	4	RBX1	2	affinity chromatography technology	Zhang DD (2005)	1
RBX1	2	CDC34	3	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down	Wu K (2002), Block K (2005), Block K (2005), Chen A (2000), Cen B (2010), Cen B (2009), DAngiolella V (2010), Spruck C (2001), Shaik S (2012), Kruiswijk F (2012), Tan M (2010), Bashir T (2010), Higa LA (2003), Kanayama A (2004), Lan L (2012), Welcker M (2011), Banks D (2006), Kumar KG (2003), Higa LA (2006), Saha A (2008), Jin J (2005), Cen B (2009), Tedesco D (2002), Choi YS (2010), Duan S (2011), Li X (2003), Wang W (2003), Gallegos JR (2008), Peschiaroli A (2009), Banerjee S (2010), Duan S (2011), Wang F (2011), Chen H (2013), Rodier G (2008), Rossi M (2013), Ungermannova D (2013), Ooi LC (2013), Ziemba A (2013), Huang H (2014), Herrero-Ruiz J (2014), Kim J (2014), Min SH (2012), Watanabe M (2011), Gao D (2010), Zhou W (2014), Canettieri G (2010), Morimoto M (2003), Chen A (2002), Pashkova N (2010), Read MA (2000), Bassermann F (2005), Duda DM (2008), Enchev RI (2012), Fukushima H (2013), Tintignac LA (2005), Ungermannova D (2005), Low TY (2014), Walter D (2016), Gao J (2015), Orthwein A (2015), Wu K (2016), Wu K (2016), Nateri AS (2004), Pierce NW (2009), Kim JH (2015), Shimizu K (2017), Gschweitl M (2016), Ibarra R (2016), Kuang P (2016), Kuang P (2016), Kuang P (2016), Ferretti LP (2016), Kuchay S (2017), Gazdoiu S (2007), Dai X (2017)	75
FBXW8	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Okabe H (2007), Xu X (2008)	3
FBXO2	0	UBE2L3	1	pull down	Nelson RF (2006)	1
UBXN7	3	VHL	0	affinity chromatography technology	Alexandru G (2008)	1
RNF126	2	SKP2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBX1	2	MTSS1	1	affinity chromatography technology	Zhong J (2013)	1
HIF1A	1	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Baek JH (2007), Hubbi ME (2011), Liu YV (2007), Luo W (2010), Liu YV (2007), Russell RC (2008)	6
SMAD3	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, two hybrid	Fukuchi M (2001), Fukuchi M (2001), Fukuchi M (2001)	3
SMAD3	1	PML	7	affinity chromatography technology	Lin HK (2004)	1
UBXN7	3	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Bandau S (2012), Besten Wd (2012), Besten Wd (2012), Bennett EJ (2010), Besten Wd (2012), Raman M (2015)	8
RBX1	2	CCND3	1	affinity chromatography technology	Maeda I (2001)	1
COPS5	0	FBXO11	14	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
LRRC14	2	ELOC	0	affinity chromatography technology	Olma MH (2009)	1
MAPK8IP2	5	RBX1	2	two hybrid	Vinayagam A (2011)	1
CUL3	17	HSPB1	2	affinity chromatography technology	Bennett EJ (2010)	1
SKP2	2	BTRC	1	affinity chromatography technology, pull down, affinity chromatography technology	Wei S (2012), Wei S (2012), Wei S (2012)	3
NEDD8	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1B	1	SKP1	0	unspecified method, unspecified method	Carrano AC (1999), Ooi LC (2013)	2
BTRC	1	HSPB1	2	affinity chromatography technology	Coyaud E (2015)	1
UBE2M	0	DCUN1D2	0	pull down, x-ray crystallography, affinity chromatography technology, pull down	Monda JK (2013), Monda JK (2013), Meyer-Schaller N (2009), Keuss MJ (2016)	4
DDA1	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Behrends C (2010), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Wan C (2015)	6
SKP2	2	ELOC	0	affinity chromatography technology	Kimura Y (2007)	1
CUL3	17	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	DCUN1D2	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXW11	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Sowa ME (2009), Watanabe N (2004), Fuchs SY (1999), Tan P (1999), Herter JR (2002), Lievens S (2009), Lievens S (2009), DAnnibale S (2014), Kim TY (2014), Kim TY (2014), Coyaud E (2015), Low TY (2014), Hein MY (2015), Liu X (2017), Hauri S (2016)	16
CUL2	3	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
PSMA2	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bloom J (2006), Bousquet-Dubouch MP (2009), Bennett EJ (2010)	3
CUL2	3	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	EEF1A1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Morrissey C (2015)	2
DET1	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Angers S (2006), Jin J (2006), Pick E (2007), Huttlin EL (2017)	5
UBE2M	0	DCUN1D4	0	pull down, pull down	Monda JK (2013), Keuss MJ (2016)	2
ABTB2	2	RBX1	2	affinity chromatography technology	Maezawa S (2008)	1
CUL5	1	FBXO17	1	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	UBE2L3	1	affinity chromatography technology	Abdelmohsen K (2009)	1
UBE2D1	0	HIF1A	1	enzymatic study	Miller F (2005)	1
CUL5	1	COPS3	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
CCND3	1	APP	1	pull down	Olah J (2011)	1
FBXO7	1	UBE2D3	1	pull down, pull down	Vingill S (2016), Teixeira FR (2016)	2
CUL4A	2	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Hein MY (2015)	7
FBXW11	2	APP	1	affinity chromatography technology	Low TY (2014)	1
CUL4B	8	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Higa LA (2006)	3
CUL1	7	RICTOR	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Gao D (2010), Gao D (2010), Gao D (2010), Gao D (2010)	4
KMT5A	2	CUL4A	2	affinity chromatography technology	Wang Z (2015)	1
COPS3	1	ELOC	0	affinity chromatography technology	Olma MH (2009)	1
CUL7	4	ELAVL1	0	affinity chromatography technology	Hanson D (2014)	1
ENC1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang DD (2005), Bennett EJ (2010), Huttlin EL (2017)	3
NEDD8	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
UBE2M	0	DCUN1D5	0	pull down, affinity chromatography technology, pull down, pull down	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016)	4
IBTK	3	CAND1	2	affinity chromatography technology	Pisano A (2015)	1
CUL2	3	LRRC14	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
CUL4A	2	CUL1	7	biochemical	He YJ (2006)	1
EEF1A1	0	RBX1	2	affinity chromatography technology	Morrissey C (2015)	1
UBE2M	0	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
RBX1	2	FBXO3	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Shima Y (2008)	2
TRIM27	2	TP53	0	affinity chromatography technology, pull down, enzymatic study	Chu Y (2011), Chu Y (2011), Chu Y (2011)	3
CASP3	0	COPS6	0	enzymatic study	da Silva Correia J (2007)	1
DDB2	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
ELAVL1	0	RICTOR	4	affinity chromatography technology	Abdelmohsen K (2009)	1
CSNK1E	0	RBX1	2	two hybrid	Vinayagam A (2011)	1
MAP3K7	2	TAB1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheung PC (2004), Cheung PC (2004), Channavajhala PL (2003), Ninomiya-Tsuji J (1999), Sakurai H (2000), Liu XY (2008), Li S (2011), Li S (2011), Ear T (2010), Singhirunnusorn P (2005), Prickett TD (2008), Kim SY (2012), Jiang Z (2002), Shibuya H (1996), Shibuya H (1996), Minoda Y (2009), Minoda Y (2009), Scholz R (2010), Scholz R (2010), Scholz R (2010), Kim SI (2009), Ge B (2003), Blonska M (2005), Kishimoto K (2000), Kishimoto K (2000), Zhu Y (2013), Liu R (2014), Chen TC (2014), Moon G (2015), Ninomiya-Tsuji J (2003), Min Y (2016), St-Denis N (2016), Zhang J (2017)	33
ELAVL1	0	UBE2E2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL3	17	RHOBTB3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Berthold J (2008), Berthold J (2008), Lu A (2013), Lu A (2013), Lu A (2013), Huttlin EL (2017)	7
PML	7	SKP1	0	affinity chromatography technology	Shima Y (2008)	1
CUL4A	2	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Bennett EJ (2010)	2
UBE2D3	1	RNF126	2	two hybrid, two hybrid, pull down	Rual JF (2005), Markson G (2009), Delker RK (2013)	3
CUL4B	8	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
GRK5	7	TAB1	1	affinity chromatography technology	Wu Z (2012)	1
RFWD2	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dornan D (2006), Dornan D (2004), Dornan D (2004), Dornan D (2004), Dornan D (2004), Choi HH (2011), Yamada T (2013), Zou S (2016)	8
DET1	2	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	DCAF1	5	affinity chromatography technology	Olma MH (2009)	1
GAN	4	HSPA8	4	affinity chromatography technology	Johnson-Kerner BL (2015)	1
DTL	0	FBXO11	14	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Rossi M (2013), Rossi M (2013), Rossi M (2013), Dar A (2014)	4
UBE2D2	0	UBXN7	3	biochemical	Havugimana PC (2012)	1
SKP2	2	ESR1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhou W (2014), Zhou W (2014), Zhou W (2014)	3
CAND1	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Kim AY (2008), Zheng J (2002), Zheng J (2002), Liu J (2002), Liu J (2002)	7
RAG1	1	CUL4A	2	affinity chromatography technology	Kassmeier MD (2011)	1
DDB2	1	EZH2	4	affinity chromatography technology, affinity chromatography technology	Zhao R (2015), Zhao R (2015)	2
CAND1	2	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	RBX1	2	x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Duda DM (2008), Ohta T (1999), Furukawa M (2002), Tron AE (2012), Tron AE (2012), Yu Y (2004), Huang DT (2009), Wang X (2015), Wang X (2015), Wang X (2015)	10
CUL7	4	CUL9	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dowell JD (2007), Skaar JR (2007), Skaar JR (2007), Skaar JR (2007), Skaar JR (2005), Skaar JR (2005)	6
NEDD8	0	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
RIPK4	0	CSNK1E	0	affinity chromatography technology	Rodriguez J (2016)	1
LRR1	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
COPS5	0	DDB2	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), He YJ (2006), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
FBXO22	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2007), Hein MY (2015), Tian X (2015), Hauri S (2016)	4
FBXO6	0	COPS3	1	affinity chromatography technology	Liu B (2012)	1
NEDD8	0	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Hauri S (2016)	3
CASP1	1	KEAP1	0	affinity chromatography technology	Garstkiewicz M (2017)	1
NEDD8	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
CUL4B	8	TP53	0	affinity chromatography technology	Thirunavukarasou A (2014)	1
CUL5	1	DDB2	1	affinity chromatography technology	Bennett EJ (2010)	1
HSPB1	2	SERTAD1	0	two hybrid	Wang J (2011)	1
DCUN1D4	0	CUL4A	2	pull down, enzymatic study	Monda JK (2013), Monda JK (2013)	2
UBE2L3	1	UBXN1	0	biochemical	Havugimana PC (2012)	1
FBXO17	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Yoshida Y (2011), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	6
CBX5	3	SUV39H1	0	two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Fujita N (2003), Rual JF (2005), Nozawa RS (2010), Rolland T (2014), Huttlin EL (2017), Hauri S (2016)	6
CUL5	1	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	FBXW2	0	enzymatic study	Cenciarelli C (1999)	1
SAMHD1	3	SKP2	2	affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014)	2
COPS3	1	KLHL18	2	affinity chromatography technology	Olma MH (2009)	1
FEM1B	1	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mahrour N (2008), Bennett EJ (2010), Kamura T (2004), Kamura T (2004)	4
DET1	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Pick E (2007), Pick E (2007), Olma MH (2009), Pick E (2007), Huttlin EL (2017)	6
LRR1	1	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
UBXN1	0	UBXN7	3	affinity chromatography technology	Raman M (2015)	1
MTSS1	1	SKP1	0	affinity chromatography technology	Zhong J (2013)	1
CUL2	3	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	3
UBE2L6	0	TRIM27	2	two hybrid	Markson G (2009)	1
FBXO6	0	COPS4	0	affinity chromatography technology	Liu B (2012)	1
FBXO6	0	EEF1A1	0	affinity chromatography technology	Liu B (2012)	1
SMAD3	1	ERBIN	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Warner DR (2003), Xi Q (2008), Brown KA (2008), Dai F (2007), Dai F (2007), Dai F (2007)	6
EEF1A1	0	HSPA8	4	affinity chromatography technology	Aranda-Orgilles B (2008)	1
UBE2D2	0	CUL3	17	pull down	Plafker KS (2009)	1
PSMA2	1	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bousquet-Dubouch MP (2009), Hauri S (2016)	2
AIRE	3	RBX1	2	affinity chromatography technology	Shao W (2016)	1
HSPB1	2	HSPA8	4	biochemical	Wan C (2015)	1
COPS7A	0	DTL	0	affinity chromatography technology	Hein MY (2015)	1
DCUN1D1	0	ELOC	0	affinity chromatography technology	Bennett EJ (2010)	1
HOXB4	2	CUL4A	2	affinity chromatography technology	Ohno Y (2010)	1
CCND2	2	TUBA1B	0	affinity chromatography technology	Russo LC (2017)	1
ELAVL1	0	FXR1	0	affinity chromatography technology	Abdelmohsen K (2009)	1
RFWD2	0	UBE2D2	0	pull down, pull down, pull down	Dornan D (2006), Dornan D (2004), Choi HH (2011)	3
CUL5	1	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stotland A (2012), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Scherer PC (2016)	5
CUL3	17	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
CSNK1E	0	ELOB	1	affinity chromatography technology	Varjosalo M (2013)	1
RBX1	2	UBE2L3	1	pull down, pull down, pull down	Cui Y (2011), Liu Y (2015), Liu Y (2015)	3
BTRC	1	RIPK4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loveless TB (2015), Loveless TB (2015), Rodriguez J (2016)	3
FBXO25	1	FBXO32	2	affinity chromatography technology	Teixeira FR (2010)	1
COPS5	0	ELOB	1	affinity chromatography technology	Bennett EJ (2010)	1
RBX1	2	VRK2	1	pull down	Kim S (2014)	1
COPS6	0	LRR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
LRRC14	2	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
TAB1	1	RBX1	2	two hybrid	Vinayagam A (2011)	1
EZH2	4	RBX1	2	affinity chromatography technology	Hein MY (2015)	1
ELOB	1	RBX1	2	affinity chromatography technology, affinity chromatography technology	Kamura T (2002), Brower CS (2002)	2
CUL1	7	FBXL5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vashisht AA (2009), Salahudeen AA (2009), Liu B (2012), Vinas-Castells R (2013), Moroishi T (2014), Moroishi T (2014), Chen ZW (2015), Wu WD (2016), Huttlin EL (2017)	9
DET1	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Huttlin EL (2017)	2
RBX1	2	ERBIN	5	enzymatic study	Kuang P (2016)	1
FBXO7	1	UBE2M	0	enzymatic study	Teixeira FR (2016)	1
CUL4B	8	TRIM27	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXO25	1	UBE2E3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DCAF1	5	COPS4	0	affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009)	2
SKP1	0	FBXW7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Wu G (2001), Wu G (2001), Wu G (2001), Hao B (2007), Schuelein C (2011), Busino L (2012), Busino L (2012), Busino L (2012), Matsumoto A (2011), Watanabe N (2004), Strohmaier H (2001), Choi BH (2014), Yumimoto K (2012), Kourtis N (2015), Kourtis N (2015), Hao J (2015), Tian X (2015), Liu YQ (2015), Gorelik M (2016), Gorelik M (2016), Gorelik M (2016), Yeh CH (2016), Reiterer V (2017), Reiterer V (2017), Reiterer V (2017), Kuchay S (2017), Ye M (2017)	28
RBX1	2	GLMN	2	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, pull down	Tron AE (2012), Tron AE (2012), Duda DM (2012), Duda DM (2012), Tron AE (2012), Tron AE (2012)	6
TP53	0	MED8	0	genetic interference	Xie L (2013)	1
DDB1	6	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Norman JA (2006), Bennett EJ (2010)	3
HOXB4	2	RBX1	2	affinity chromatography technology	Ohno Y (2010)	1
RBX1	2	CUL7	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Dias DC (2002), Dias DC (2002), Andrews P (2006), Andrews P (2006), Huber C (2005), Huber C (2005), Xu X (2012), Nie J (2015)	9
DIO2	0	ELOB	1	affinity chromatography technology	Dentice M (2005)	1
FBXL12	1	UBE2D3	1	pull down	Nishiyama M (2015)	1
COPS5	0	FBXL5	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
BTRC	1	CAND1	2	affinity chromatography technology	Coyaud E (2015)	1
RBX1	2	GHR	1	unspecified method	Bulatov E (2015)	1
CUL5	1	BTRC	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
FBXO6	0	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2007), Yoshida Y (2007), Nelson RF (2007), Glenn KA (2008), Yoshida Y (2011), Liu B (2012), Liu B (2012), Tian X (2015), Hauri S (2016)	9
VHL	0	CBX5	3	affinity chromatography technology	Lai Y (2012)	1
GAN	4	HSPA1A	0	affinity chromatography technology	Johnson-Kerner BL (2015)	1
ESR1	0	HSPB1	2	affinity chromatography technology, pull down	Kanaujiya JK (2013), Nalvarte I (2010)	2
COPS6	0	FBXO11	14	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
CUL7	4	TUBA1B	0	affinity chromatography technology	Hanson D (2014)	1
DDA1	1	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Lu G (2014)	2
DTL	0	UBE2D1	0	pull down	Terai K (2010)	1
COPS5	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), He F (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CUL3	17	FBXO3	0	affinity chromatography technology	Bennett EJ (2010)	1
DET1	2	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
HSPB1	2	PSMA6	1	two hybrid	Katsogiannou M (2014)	1
CAND1	2	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	CORO7	0	affinity chromatography technology	Watanabe M (2011)	1
LRR1	1	ELOC	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kamura T (2004), Kamura T (2004)	3
PSMA2	1	CAND1	2	affinity chromatography technology	Bousquet-Dubouch MP (2009)	1
RIPK4	0	HSPB1	2	affinity chromatography technology	Rodriguez J (2016)	1
COPS3	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
HINT1	0	CDC34	3	pull down, affinity chromatography technology, affinity chromatography technology	Cen B (2009), Cen B (2009), Cen B (2009)	3
COPS6	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
DCUN1D4	0	CAND1	2	affinity chromatography technology, pull down	Keuss MJ (2016), Keuss MJ (2016)	2
FBXO7	1	CSNK1E	0	enzymatic study	Teixeira FR (2016)	1
DCUN1D2	0	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
DDA1	1	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
PSMA2	1	EEF1A1	0	affinity chromatography technology	Bousquet-Dubouch MP (2009)	1
RAG1	1	DDB1	6	biochemical, affinity chromatography technology	Kassmeier MD (2011), Kassmeier MD (2011)	2
NEDD8	0	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	CDKN1B	1	enzymatic study	Ryu KS (2008)	1
COPS5	0	HIF1A	1	affinity chromatography technology, pull down, affinity chromatography technology	Bemis L (2004), Bemis L (2004), No YR (2015)	3
FBXO2	0	CUL7	4	affinity chromatography technology	Wen H (2010)	1
FBXO2	0	UBE2D2	0	pull down, pull down	Yoshida Y (2002), Nelson RF (2006)	2
BTRC	1	GHR	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	van Kerkhof P (2007), da Silva Almeida AC (2012), da Silva Almeida AC (2013), da Silva Almeida AC (2013)	4
GRK5	7	SKP1	0	affinity chromatography technology	Wu Z (2012)	1
ELAVL1	0	MAP3K20	1	affinity chromatography technology	Abdelmohsen K (2009)	1
PTGS2	0	CUL4A	2	affinity chromatography technology	Neuss H (2007)	1
CUL4B	8	APP	1	pull down	Olah J (2011)	1
KBTBD7	3	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Bennett EJ (2010), Genau HM (2015), Genau HM (2015), Huttlin EL (2017)	5
COPS5	0	DDA1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
FBXW8	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okabe H (2007), Ponyeam W (2012), Litterman N (2011), Bennett EJ (2010), Liu B (2012), Low TY (2014), Reitsma JM (2017)	7
CUL1	7	FBXO22	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Liu B (2012), Reitsma JM (2017)	3
PSMA2	1	PSMA6	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, biochemical	Bloom J (2006), Claverol S (2002), Jayarapu K (2004), Bousquet-Dubouch MP (2009), Havugimana PC (2012), Froment C (2005), Froment C (2005), Kristensen AR (2012), Wan C (2015)	9
COPS6	0	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	4
FBXL5	3	COPS6	0	affinity chromatography technology	Huttlin EL (2017)	1
RBX1	2	MAGEC2	0	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Hao J (2015), Hao J (2015), Hao J (2015), Hao J (2015)	4
FBXO6	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Yoshida Y (2011)	2
CCND3	1	CDKN1B	1	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Lin J (2001), Lin J (2001), Zhang Q (1999), Barnouin K (1999), Barnouin K (1999), Datta NS (1998), Vlach J (1996), Bockstaele L (2006), Bockstaele L (2006), Waaijers S (2013), Waaijers S (2013), Huttlin EL (2015), Huttlin EL (2017)	14
HIST1H1A	0	EZH2	4	pull down	Martin C (2006)	1
GRK5	7	RBX1	2	affinity chromatography technology	Wu Z (2012)	1
KDM2B	11	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koyama-Nasu R (2007), Han XR (2016), Han XR (2016)	3
RBX1	2	UBE2E3	0	pull down	Pick E (2007)	1
CUL7	4	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Tsutsumi T (2008), Xu X (2012), Hauri S (2016)	4
RBX1	2	CUL4A	2	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, enzymatic study, pull down, biochemical	Dias DC (2002), Ohta T (1999), Guerrero-Santoro J (2008), Hu J (2004), Furukawa M (2002), Maddika S (2009), Tron AE (2012), Tron AE (2012), He YJ (2006), Gastaldello S (2012), Olma MH (2009), Kristensen AR (2012), Huang DT (2009), Pick E (2007), Yang Y (2016), Scherer PC (2016), Nguyen TV (2016)	17
UBXN7	3	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down	Bandau S (2012), Besten Wd (2012), Kelsall IR (2013)	3
CUL7	4	HIST1H4A	0	affinity chromatography technology	Hanson D (2014)	1
AIRE	3	FBXO3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shao W (2016), Shao W (2016), Shao W (2016)	3
VRK2	1	TP53	0	enzymatic study, affinity chromatography technology	Blanco S (2006), Blanco S (2006)	2
RBX1	2	CDKN1B	1	enzymatic study	Duda DM (2008)	1
CUL5	1	CUL2	3	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
BTRC	1	MTSS1	1	affinity chromatography technology	Zhong J (2013)	1
NEDD4	2	CUL1	7	affinity chromatography technology	Liu J (2014)	1
MAP3K20	1	EZH2	4	two hybrid	Vinayagam A (2011)	1
FBXW7	2	TP53	0	affinity chromatography technology	Huttlin EL (2017)	1
ERCC8	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Groisman R (2003), Groisman R (2003), Groisman R (2006), Groisman R (2006)	4
CUL1	7	FBXO21	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Watanabe K (2015), Zhang C (2015), Zhang C (2015), Reitsma JM (2017)	5
CUL1	7	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Menon S (2008), Chew EH (2007), Min KW (2005), Min KW (2005), Min KW (2005), Hwang JW (2003), Hwang JW (2003), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012), Zheng J (2002), Zheng J (2002), Bornstein G (2006), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), He YJ (2006), Emberley ED (2012), Choo YY (2011), Jonason JH (2007), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Liu J (2002), Liu J (2002), Korzeniewski N (2012), Pierce NW (2013), Kim AY (2008), Zhang S (2016), Tikhmyanova N (2017), Tikhmyanova N (2017), Reitsma JM (2017), Reitsma JM (2017)	41
VRK2	1	MAP3K7	2	affinity chromatography technology	Blanco S (2008)	1
FBXW2	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Saiga T (2009), Bennett EJ (2010), Busino L (2003), Liu B (2012), Low TY (2014), Xu J (2017), Reitsma JM (2017)	8
GRK5	7	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012), Wu Z (2012)	3
SKP2	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Min KW (2003), Lisztwan J (1998), Lisztwan J (1998), Marti A (1999), Zheng N (2002), Menon S (2008), Chew EH (2007), Chew EH (2007), Ji P (2006), Sabile A (2006), Tan P (1999), Lin HK (2009), Nie L (2011), Chua YS (2011), Huang Z (2004), Wu J (2012), Koyama-Nasu R (2007), Bashir T (2010), Saiga T (2009), Choo YY (2011), Jonason JH (2007), Jonason JH (2007), Bennett EJ (2010), Michel JJ (1998), Carrano AC (1999), Lyapina SA (1998), Lyapina SA (1998), Wu J (2012), Yu ZK (1998), Yu ZK (1998), Rodier G (2008), Swarnalatha M (2013), Cordero-Espinoza L (2013), Yumimoto K (2013), Chung FZ (2014), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Zhang S (2016), Zhang S (2016), Huttlin EL (2017), Kuchay S (2017), Reitsma JM (2017), Reitsma JM (2017), Ma X (2017)	46
DCUN1D2	0	APP	1	pull down	Olah J (2011)	1
FBXO7	1	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
DCUN1D1	0	RBX1	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bommelje CC (2013), Meyer-Schaller N (2009), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	9
COPS6	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
KLHL3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Ohta A (2013), Ohta A (2013), Wakabayashi M (2013), Ji AX (2013), Shibata S (2013), Shibata S (2013), Takahashi D (2013), McCormick JA (2014), Rolland T (2014), Ibeawuchi SR (2015), Schumacher FR (2015), Schumacher FR (2015), Wu G (2013)	13
CCNF	2	RBX1	2	affinity chromatography technology	Yoshida Y (2011)	1
RIPK4	0	CUL1	7	affinity chromatography technology	Rodriguez J (2016)	1
FBXL12	1	PRAME	2	affinity chromatography technology, affinity chromatography technology	Tan MK (2013), Tan MK (2013)	2
FXR1	0	SKP1	0	affinity chromatography technology	Qie S (2017)	1
COPS4	0	LRRC14	2	affinity chromatography technology	Olma MH (2009)	1
HSPA8	4	MYB	3	affinity chromatography technology	Li L (2013)	1
FBXO18	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim J (2002), Kim J (2002), Kim JH (2004), Bennett EJ (2010), Jeong YT (2013), Jeong YT (2013), Reitsma JM (2017)	7
PTGS2	0	CUL1	7	affinity chromatography technology	Neuss H (2007)	1
FBXO27	0	CUL1	7	affinity chromatography technology, affinity chromatography technology	Glenn KA (2008), Yoshida Y (2011)	2
GLMN	2	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
MAP4K1	1	RBX1	2	affinity chromatography technology	Wang H (2014)	1
HSPB1	2	GLMN	2	two hybrid	Katsogiannou M (2014)	1
APP	1	MAPK8IP2	5	affinity chromatography technology	Muresan Z (2005)	1
DCUN1D1	0	KLHL18	2	affinity chromatography technology	Bennett EJ (2010)	1
UBXN1	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Bennett EJ (2010)	3
GLMN	2	SKP1	0	pull down	Tron AE (2012)	1
CDKN1B	1	HSPA8	4	affinity chromatography technology	Imamura Y (2016)	1
RIPK4	0	RICTOR	4	affinity chromatography technology	Rodriguez J (2016)	1
DDB1	6	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Jin J (2006), Jin J (2006), Ahn J (2010), Maddika S (2009), Maddika S (2009), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Hrecka K (2007), Le Rouzic E (2007), Le Rouzic E (2007), Olma MH (2009), Pham TN (2011), Gerard FC (2014), Nakagawa T (2015), Wan C (2015), Kyei GB (2015), Cassiday PA (2015), Gao J (2015), Gao J (2015), Wu Y (2016), Wu Y (2016), Wang H (2017), Zhou X (2016), Zhou X (2016), Wang X (2017)	26
COPS5	0	HSPB1	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	SKP1	0	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Angers S (2006), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009)	7
DET1	2	RBX1	2	affinity chromatography technology	Wertz IE (2004)	1
ELAVL1	0	FBXO27	0	affinity chromatography technology	Abdelmohsen K (2009)	1
MAP4K1	1	CUL7	4	affinity chromatography technology	Wang H (2014)	1
COPS6	0	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Chua YS (2011), Chua YS (2011), Tron AE (2012), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Schumacher FR (2015), Schumacher FR (2015), Lo SC (2006), Lo SC (2006)	12
ELAVL1	0	RBX1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
COPS5	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
CUL4A	2	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
MKNK2	1	CUL2	3	two hybrid	Wang P (2006)	1
FBXO7	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vingill S (2016), Teixeira FR (2016), Teixeira FR (2016)	3
CCND1	1	CUL7	4	affinity chromatography technology	Okabe H (2007)	1
FBXO44	0	CUL4B	8	affinity chromatography technology	Sjoegren B (2015)	1
DDB1	6	CAND1	2	affinity chromatography technology	Hu J (2004)	1
COPS5	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
HSPB1	2	TP53	0	two hybrid, affinity chromatography technology, imaging technique	Stelzl U (2005), Sun Y (2007), Chen TC (2014)	3
NEDD8	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Wimuttisuk W (2007)	4
UBXN7	3	ELOC	0	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bandau S (2012)	2
VHL	0	HIST1H1C	2	pull down	Lai Y (2012)	1
FBXO2	0	RBX1	2	affinity chromatography technology	Glenn KA (2008)	1
FBXW8	2	UBE2D3	1	pull down	Okabe H (2007)	1
COPS5	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Pick E (2012)	7
EZH2	4	ELAVL1	0	affinity chromatography technology	Cao Q (2014)	1
KDM2B	11	SKP1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gearhart MD (2006), Koyama-Nasu R (2007), Inagaki T (2015), Inagaki T (2015), Busino L (2007), Han XR (2016), Kuchay S (2017), Hauri S (2016)	8
DCAF1	5	MCM10	2	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kaur M (2012), Kaur M (2012), Romani B (2015), Romani B (2015)	4
FBXW11	2	EZH2	4	affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Low TY (2014)	2
PTGS2	0	RBX1	2	affinity chromatography technology	Neuss H (2007)	1
TP53	0	KCTD17	0	affinity chromatography technology	Horikawa I (2014)	1
NEDD8	0	KBTBD7	3	affinity chromatography technology	Bennett EJ (2010)	1
HIF1A	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL1	7	HSPA8	4	affinity chromatography technology	Bennett EJ (2010)	1
SMAD3	1	ESR1	0	affinity chromatography technology	Ito I (2010)	1
CBX5	3	ELOC	0	two hybrid	Wang J (2011)	1
COPS6	0	FBXO42	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	APP	1	pull down, affinity chromatography technology	Olah J (2011), Wang H (2013)	2
NEDD4	2	CUL5	1	affinity chromatography technology	Zhou W (2014)	1
IBTK	3	RBX1	2	affinity chromatography technology	Pisano A (2015)	1
ING3	3	SKP2	2	affinity chromatography technology, affinity chromatography technology	Chen G (2010), Chen G (2010)	2
IP6K1	5	CUL4A	2	affinity chromatography technology	Rao F (2014)	1
RFWD2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Olma MH (2009)	2
HIF1A	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down	Ryu JH (2011), Ryu JH (2011), Ryu JH (2011)	3
SMAD3	1	NEDD4	2	affinity chromatography technology, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down	Kuratomi G (2005), Persaud A (2009), Aragon E (2011), Aragon E (2011), Aragon E (2011), Aragon E (2011)	6
MAP4K1	1	SKP1	0	affinity chromatography technology	Wang H (2014)	1
UBE2E3	0	CUL3	17	pull down	Plafker KS (2009)	1
CDKN1B	1	CUL1	7	unspecified method, pull down	Carrano AC (1999), Enchev RI (2012)	2
COPS6	0	LRRC14	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
UBE2E3	0	CUL1	7	pull down	Plafker KS (2009)	1
UBE2E2	1	TRIM27	2	two hybrid	Napolitano LM (2011)	1
UBE2D1	0	CAND1	2	biochemical	You J (2001)	1
RHOBTB3	1	HIF1A	1	affinity chromatography technology	Zhang CS (2015)	1
ERCC8	1	GPS1	1	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2