PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
PLK1	0	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Lin DC (2011), Lin DC (2011)	2
CAND1	2	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	WWP2	7	affinity chromatography technology	Emdal KB (2015)	1
TRIM63	0	USP4	3	enzymatic study	Loch CM (2012)	1
CDK11A	1	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
EPS15L1	1	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
CDH1	4	TRIM25	5	bioid	Guo Z (2014)	1
TRIM5	4	UBC	7	enzymatic study	Pertel T (2011)	1
MCM2	3	MYH2	2	affinity chromatography technology	Drissi R (2015)	1
WEE1	2	USP15	4	affinity chromatography technology	Boldt K (2016)	1
TRIM25	5	MKNK2	1	affinity chromatography technology	Choudhury NR (2017)	1
HIST2H2AC	1	HIST2H2BE	1	pull down	Long L (2014)	1
MCM2	3	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
USP10	2	HIST2H2AC	1	enzymatic study	Draker R (2011)	1
SOX2	4	CDK11A	1	affinity chromatography technology	Cox JL (2013)	1
SMURF2	3	TRAF4	1	two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, enzymatic study	Colland F (2004), Zhang L (2013), Zhang L (2013), Zhang L (2013), Zhang L (2013), Zhang L (2013), Zhang L (2013), Zhang L (2013)	8
MCM6	5	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
SMAD4	9	ZMYM2	5	two hybrid	Colland F (2004)	1
USP28	3	USP33	1	enzymatic study	Loch CM (2012)	1
COPS5	0	HNRNPL	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei T (2017)	2
TRAF6	0	UBC	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Muroi M (2011), Park S (2013), Sun L (2004), Kanayama A (2004), Sakamoto H (2015), Yu J (2016), Middleton AJ (2017)	7
SMAD7	1	CTNNB1	30	affinity chromatography technology, imaging technique, affinity chromatography technology	Edlund S (2005), Edlund S (2005), Tang Y (2008)	3
USP15	4	BMPR1B	3	affinity chromatography technology	Herhaus L (2014)	1
NPM1	0	KEAP1	0	affinity chromatography technology	Chen R (2013)	1
EGLN3	0	YAP1	0	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	USP7	14	affinity chromatography technology	Rodriguez J (2016)	1
SMAD6	9	SMAD7	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Topper JN (1997), Topper JN (1997), Topper JN (1997), Yan X (2016)	4
TRIM63	0	SENP3	1	enzymatic study	Loch CM (2012)	1
TRIM21	0	TRIM5	4	pull down	Li X (2006)	1
FERMT3	4	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
USP7	14	WWP2	7	two hybrid, affinity chromatography technology	Lim J (2006), Chaudhary N (2014)	2
HNRNPL	3	EPS15L1	1	affinity chromatography technology	Fei T (2017)	1
RHPN1	2	USP15	4	affinity chromatography technology	Huttlin EL (2017)	1
OTUB1	0	ADSL	5	affinity chromatography technology	Scholz CC (2016)	1
NXF1	0	SHC1	0	affinity chromatography technology	Castello A (2012)	1
UCHL1	1	COPS5	0	two hybrid, affinity chromatography technology	Caballero OL (2002), Caballero OL (2002)	2
EPS15L1	1	CDK11A	1	affinity chromatography technology	Boldt K (2016)	1
MDM2	2	PHF7	5	two hybrid	Woodsmith J (2012)	1
SENP3	1	TP53	0	affinity chromatography technology, imaging technique	Nishida T (2011), Nishida T (2011)	2
USP15	4	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
PRPF4	3	TUT1	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017)	2
COPS5	0	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
USP7	14	HIST2H2BE	1	affinity chromatography technology	Lecona E (2015)	1
TRIM54	1	YOD1	0	enzymatic study	Loch CM (2012)	1
NTRK1	1	ATG2B	11	affinity chromatography technology	Emdal KB (2015)	1
CYLD	2	USP10	2	affinity chromatography technology	Elliott PR (2016)	1
USP28	3	JOSD1	1	enzymatic study	Loch CM (2012)	1
USP15	4	BMPR1A	5	affinity chromatography technology, imaging technique, enzymatic study	Herhaus L (2014), Herhaus L (2014), Herhaus L (2014)	3
MCM4	3	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
SMAD7	1	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mochizuki T (2004), Asano Y (2004), Koinuma D (2003), Kavsak P (2000), Hayashi H (1997), Hayashi H (1997), Datta PK (2000), Wicks SJ (2005), Lallemand F (2005), Seong HA (2007), Yan X (2011), Cai Y (2012), Cai Y (2012), Seo SR (2004), Zhu L (2012), Zhu L (2012), Nakao A (1997), Yan X (2009), Kamiya Y (2010), Suzuki C (2002), Hsu HY (2014)	21
TRIM54	1	USP33	1	enzymatic study	Loch CM (2012)	1
NTRK1	1	USP7	14	affinity chromatography technology	Emdal KB (2015)	1
CUL3	17	MEPCE	1	affinity chromatography technology	Bennett EJ (2010)	1
HUWE1	22	LSM4	1	biochemical	Havugimana PC (2012)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
IVNS1ABP	0	HNRNPL	3	affinity chromatography technology, affinity chromatography technology	Tsai PL (2013), Tsai PL (2013)	2
USP15	4	CARD9	3	two hybrid	Rolland T (2014)	1
USP11	3	KEAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009)	3
POU5F1	0	GTF3C4	0	affinity chromatography technology	Oliviero G (2015)	1
RNF126	2	USP7	14	affinity chromatography technology	OConnor HF (2015)	1
MCM4	3	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
EGLN3	0	AXIN1	1	affinity chromatography technology	Rodriguez J (2016)	1
USP11	3	UBC	7	enzymatic study, pull down, pull down	Faesen AC (2011), Zhang X (2017), Kwasna D (2018)	3
PPIH	1	LSM4	1	affinity chromatography technology	Boldt K (2016)	1
USP7	14	HIST2H2AC	1	affinity chromatography technology, enzymatic study	Lecona E (2015), Yu M (2016)	2
CAND1	2	HNRNPL	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei T (2017)	2
GTF3C4	0	GTF3C2	2	affinity chromatography technology, pull down, affinity chromatography technology, biochemical	Hsieh YJ (1999), Hsieh YJ (1999), Sinn E (1995), Havugimana PC (2012)	4
TRIM21	0	USP4	3	two hybrid, enzymatic study, enzymatic study, two hybrid	Di Donato F (2001), Wada K (2006), Wada K (2006), Hayes SD (2012)	4
TRIM63	0	YOD1	0	enzymatic study	Loch CM (2012)	1
FHL1	1	SMAD3	1	pull down, affinity chromatography technology, affinity chromatography technology	Ding L (2009), Ding L (2009), Ding L (2009)	3
TERF2	2	USP15	4	affinity chromatography technology	Giannone RJ (2010)	1
USP10	2	USP15	4	biochemical	Havugimana PC (2012)	1
NTRK1	1	IRS2	6	affinity chromatography technology	Emdal KB (2015)	1
COPS5	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	11
TRIM25	5	NOTCH1	25	affinity chromatography technology	Choudhury NR (2017)	1
ACVR1	4	SMURF1	4	affinity chromatography technology	Murakami G (2003)	1
BAP1	4	PSMD11	0	affinity chromatography technology	Hauri S (2016)	1
TRAF6	0	USP20	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Jean-Charles PY (2016), Jean-Charles PY (2016), Yasunaga J (2011), Yasunaga J (2011)	4
TRIM63	0	UCHL3	1	enzymatic study	Loch CM (2012)	1
SPAG9	5	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
SORT1	1	USP15	4	affinity chromatography technology	Hein MY (2015)	1
USP4	3	TUT1	3	affinity chromatography technology	Sowa ME (2009)	1
HNRNPL	3	UBE2E3	0	affinity chromatography technology	Fei T (2017)	1
BIRC2	1	UBE2S	2	two hybrid, pull down	Dynek JN (2010), Phu L (2011)	2
SMURF2	3	SMURF1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fukunaga E (2008), Fukunaga E (2008), Lee YS (2011), Huttlin EL (2017)	4
MED4	2	CDK11A	1	affinity chromatography technology	Lambert JP (2015)	1
BCR	3	SPAG9	5	affinity chromatography technology	Boldt K (2016)	1
PGAM2	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Mikawa T (2014), Mikawa T (2014), Mikawa T (2014)	3
NOTCH1	25	USP15	4	affinity chromatography technology	Yatim A (2012)	1
UBE2G2	0	USP15	4	affinity chromatography technology	Ewing RM (2007)	1
BCAT1	6	USP15	4	affinity chromatography technology	Huttlin EL (2015)	1
USP15	4	TRIM46	3	two hybrid	Hayes SD (2012)	1
IVNS1ABP	0	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
BCR	3	WEE1	2	affinity chromatography technology	Boldt K (2016)	1
CDK11A	1	SPAG9	5	affinity chromatography technology	Boldt K (2016)	1
USP15	4	RNF126	2	two hybrid	Hayes SD (2012)	1
MCM4	3	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
KRT31	0	TRAF4	1	two hybrid	Rolland T (2014)	1
USP15	4	PRPF31	0	affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Das T (2017), Das T (2017)	3
USP15	4	CCDC57	8	two hybrid	Rolland T (2014)	1
OTUB1	0	SMAD4	9	affinity chromatography technology, pull down	Herhaus L (2013), Herhaus L (2013)	2
MCM2	3	PHB2	1	affinity chromatography technology	Drissi R (2015)	1
TRAF6	0	TP53	0	enzymatic study, affinity chromatography technology	Zhang X (2016), Zhang X (2016)	2
BMPR1A	5	SMURF1	4	affinity chromatography technology	Murakami G (2003)	1
USP20	3	PSMD11	0	affinity chromatography technology	Sowa ME (2009)	1
MCM2	3	MCM7	5	pull down, pull down, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), You Z (1999), Fujita M (1997), You Z (2002), Havugimana PC (2012), Ramachandran N (2004), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Drissi R (2015), Boldt K (2016)	14
USP15	4	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
OTUB1	0	UBE2G2	0	affinity chromatography technology	Scholz CC (2016)	1
POU5F1	0	WWP2	7	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study	Xu H (2009), Xu H (2009), Xu H (2009), Qian YW (2012), Liao B (2010)	5
CDH1	4	ANK3	16	bioid	Guo Z (2014)	1
TGFBR1	2	OTUB1	0	enzymatic study, affinity chromatography technology	Herhaus L (2015), Herhaus L (2015)	2
CUL3	17	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
BAG6	2	ECHS1	2	affinity chromatography technology	Hein MY (2015)	1
CUL3	17	ALDOA	0	affinity chromatography technology	Bennett EJ (2010)	1
USP15	4	KRT85	5	affinity chromatography technology	Sowa ME (2009)	1
SORT1	1	USP11	3	affinity chromatography technology	Hein MY (2015)	1
HUWE1	22	HIST2H2BE	1	affinity chromatography technology	Thompson JW (2014)	1
CUL3	17	KRT33B	1	affinity chromatography technology	Bennett EJ (2010)	1
TERF2	2	MCM7	5	affinity chromatography technology	Giannone RJ (2010)	1
SPAG9	5	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
ECHS1	2	ALDOA	0	biochemical	Wan C (2015)	1
IVNS1ABP	0	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
TRIM54	1	UCHL1	1	enzymatic study	Loch CM (2012)	1
GTF3C4	0	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
UBC	7	ADSL	5	affinity chromatography technology	Matsumoto M (2005)	1
IRS2	6	USP7	14	affinity chromatography technology	Fukushima T (2017)	1
IVNS1ABP	0	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
RBCK1	0	UBC	7	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, pull down, pull down, pull down, enzymatic study, pull down	Tatematsu K (2008), Yoshimoto N (2009), Sato Y (2011), Kirisako T (2006), Haas TL (2009), Yoshimoto N (2009), Sato Y (2011), Emmerich CH (2013), Emmerich CH (2013), Zhang X (2017)	10
USP15	4	USP14	1	enzymatic study	Loch CM (2012)	1
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
LMNA	2	FHL1	1	bioid	Roux KJ (2012)	1
CYLD	2	USP15	4	affinity chromatography technology	Elliott PR (2016)	1
TRIM54	1	USP7	14	enzymatic study	Loch CM (2012)	1
SMAD7	1	SMURF2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Asano Y (2004), Kavsak P (2000), Lee YS (2008), Komuro A (2004), Chong PA (2010), Chong PA (2010), Chong PA (2010), Cai Y (2012), Cai Y (2012), Chong PA (2006), Al-Salihi MA (2012), Ogunjimi AA (2005), Aragon E (2012), Aragon E (2012), Colland F (2004), Zhang L (2013), Chandhoke AS (2015), Iyengar PV (2015), Elkouris M (2016)	19
TRIM25	5	AXIN1	1	affinity chromatography technology	Choudhury NR (2017)	1
LSM4	1	LSM2	0	affinity chromatography technology, biochemical, biochemical	Eystathioy T (2002), Havugimana PC (2012), Wan C (2015)	3
BRAP	0	USP15	4	two hybrid, affinity chromatography technology, two hybrid	Hayes SD (2012), Hayes SD (2012), Hayes SD (2012)	3
MCM2	3	KIAA1468	5	affinity chromatography technology	Boldt K (2016)	1
TP53	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dhar SK (2006), Kurki S (2004), Kurki S (2004), Lambert B (2006), Colombo E (2002), Colombo E (2002), Colombo E (2002), Fogeron ML (2013), Li J (2005)	9
NTRK1	1	SPAG9	5	affinity chromatography technology	Emdal KB (2015)	1
SMAD3	1	BTRC	1	affinity chromatography technology	Wan M (2004)	1
WAPL	1	SMC1A	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Kueng S (2006), Hein MY (2015), Hein MY (2015)	4
USP21	2	USP28	3	enzymatic study, enzymatic study	Loch CM (2012), Loch CM (2012)	2
USP15	4	USP51	1	enzymatic study	Loch CM (2012)	1
TP53	0	RNF20	9	pull down, affinity chromatography technology	Kim J (2005), Kim J (2005)	2
PLK1	0	SPAG9	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Svendsen JM (2009), Huttlin EL (2017), Boldt K (2016)	3
UBE2E3	0	USP15	4	affinity chromatography technology	Huttlin EL (2017)	1
SOX2	4	SMC3	16	affinity chromatography technology	Cox JL (2013)	1
STN1	0	USP33	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD4	9	WEE1	2	genetic interference	Shen JP (2017)	1
USP15	4	TRAF6	0	enzymatic study	Bremm A (2010)	1
MCM2	3	PPP4R3A	3	affinity chromatography technology	Boldt K (2016)	1
CYLD	2	LMNA	2	affinity chromatography technology	Elliott PR (2016)	1
AXIN1	1	USP7	14	affinity chromatography technology	Novellasdemunt L (2017)	1
FN1	17	LMNA	2	affinity chromatography technology	Humphries JD (2009)	1
SMAD6	9	WWP2	7	affinity chromatography technology	Herhaus L (2014)	1
HUWE1	22	PSMD11	0	affinity chromatography technology	Thompson JW (2014)	1
TRAF4	1	WWP2	7	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
DDX58	3	CYLD	2	affinity chromatography technology	Friedman CS (2008)	1
BAG6	2	TRIM21	0	affinity chromatography technology	Rodrigo-Brenni MC (2014)	1
CUL3	17	KRT85	5	affinity chromatography technology	Bennett EJ (2010)	1
MCM4	3	MCM7	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology	Yabuta N (2003), Fujita M (1997), Ishimi Y (1996), You Z (2002), Havugimana PC (2012), Ramachandran N (2004), Kristensen AR (2012), Wan C (2015), Boldt K (2016)	9
MKNK2	1	BAG6	2	affinity chromatography technology	Hein MY (2015)	1
YAP1	0	SMAD2	5	affinity chromatography technology	Pefani DE (2016)	1
USP4	3	PRPF3	3	affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study	Sowa ME (2009), Song EJ (2010), Song EJ (2010), Song EJ (2010), Song EJ (2010)	5
UBC	7	TMEM132A	1	pull down	Nathan JA (2013)	1
MCM4	3	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	MCM6	5	affinity chromatography technology	Emdal KB (2015)	1
SMAD4	9	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Moren A (2003), Wotton D (1999), Mori N (2001), Wu JW (2002), Wu JW (2002), Nakao A (1997), Wicks SJ (2000), Wu JW (2001), Chen X (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Razani B (2001), Razani B (2001), Wang B (2008), Moren A (2005), Kurisaki K (2003), Prunier C (2003), Kato Y (2002), Xu J (2000), Wang L (2011), He W (2006), He W (2006), Dupont S (2009), Brown JD (1999), Pardali K (2000), Fu G (2011), Chen W (2007), Gao S (2009), Lin X (2003), Seo SR (2006), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Barrios-Rodiles M (2005), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Ali A (2013), Yamakawa N (2002), Yamakawa N (2002), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Zhou F (2017)	56
GRK5	7	COPS7A	0	affinity chromatography technology	Wu Z (2012)	1
AXIN1	1	GAPVD1	6	affinity chromatography technology	Hein MY (2015)	1
USP15	4	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
SMAD4	9	USP4	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Zhou F (2017), Zhou F (2017), Zhou F (2017), Zhou F (2017)	4
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
MCM2	3	CUL4B	8	affinity chromatography technology	Drissi R (2015)	1
SENP8	0	PLA2G2A	1	enzymatic study	Altun M (2011)	1
TRAF6	0	UCHL1	1	affinity chromatography technology	Karim R (2013)	1
USP15	4	NFE2L1	4	affinity chromatography technology	Fukagai K (2016)	1
PLK1	0	TP53	0	enzymatic study	Dias SS (2009)	1
CUL3	17	SART3	2	affinity chromatography technology	Bennett EJ (2010)	1
HSF1	1	BTRC	1	affinity chromatography technology, affinity chromatography technology	Lee YJ (2008), Lee YJ (2008)	2
TRIM63	0	ALDOA	0	two hybrid	Witt SH (2005)	1
NTRK1	1	USP11	3	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	BAP1	4	pull down, pull down, pull down, pull down	Duerksen-Hughes PJ (1989), Daou S (2015), Kwasna D (2018), Hanpude P (2017)	4
SMURF1	4	FHL1	1	affinity chromatography technology	Xie Y (2013)	1
USP15	4	LGALS7	0	affinity chromatography technology	Sowa ME (2009)	1
MCM4	3	KIAA1468	5	affinity chromatography technology	Boldt K (2016)	1
SMURF2	3	UBC	7	enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Maspero E (2013), Zhang L (2013), Kristariyanto YA (2015), Mari S (2014), Zhang Y (2017)	5
USP15	4	PRPF3	3	affinity chromatography technology	Sowa ME (2009)	1
CDH1	4	USP15	4	bioid	Guo Z (2014)	1
LSM6	0	PRPF31	0	affinity chromatography technology	Huttlin EL (2017)	1
MCM7	5	TRIM54	1	two hybrid	Rolland T (2014)	1
CYLD	2	UBC	7	enzymatic study, enzymatic study, enzymatic study, pull down	Almeida S (2008), Bremm A (2010), Komander D (2009), Kwasna D (2018)	4
BMPR1B	3	OTUB1	0	enzymatic study	Herhaus L (2015)	1
USP11	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Maertens GN (2010), Maertens GN (2010), Ma H (2012), Hein MY (2015)	7
SORT1	1	STAM	3	affinity chromatography technology	Takatsu H (2001)	1
SMURF1	4	LMNA	2	enzymatic study	Andrews PS (2010)	1
MCM2	3	NPM1	0	affinity chromatography technology	Drissi R (2015)	1
SPAG9	5	WEE1	2	affinity chromatography technology	Boldt K (2016)	1
NXF1	0	USP11	3	affinity chromatography technology	Castello A (2012)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
WWP2	7	UBC	7	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Sheng Y (2012), Maspero E (2013), Soond SM (2013), Kristariyanto YA (2015)	4
USP7	14	RBCK1	0	two hybrid	Hayes SD (2012)	1
TP53	0	CYLD	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016)	4
TCEAL4	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Hein MY (2015), Hein MY (2015)	3
GTF3C2	2	USP15	4	affinity chromatography technology	Boldt K (2016)	1
UCHL1	1	PLA2G2A	1	enzymatic study	Altun M (2011)	1
SHC1	0	BCR	3	affinity chromatography technology	Brehme M (2009)	1
SPAG9	5	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
NXF1	0	CTNNB1	30	affinity chromatography technology	Castello A (2012)	1
LMNA	2	PHB2	1	affinity chromatography technology	Depreux FF (2015)	1
PPIH	1	LSM8	0	affinity chromatography technology	Boldt K (2016)	1
SENP3	1	GTF3C4	0	affinity chromatography technology	Wang M (2016)	1
FN1	17	MCM6	5	affinity chromatography technology	Humphries JD (2009)	1
TRIM25	5	MCM7	5	affinity chromatography technology	Choudhury NR (2017)	1
YAP1	0	SMAD6	9	affinity chromatography technology	Ferrigno O (2002)	1
TRIM25	5	CTNNB1	30	affinity chromatography technology	Choudhury NR (2017)	1
SPAG9	5	MCM7	5	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	PHB2	1	affinity chromatography technology	Emdal KB (2015)	1
SMAD3	1	USP15	4	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Inui M (2011), Inui M (2011), Inui M (2011), Eichhorn PJ (2012), Wijnhoven P (2015)	5
USP21	2	SENP8	0	enzymatic study	Loch CM (2012)	1
TRIM25	5	SART3	2	affinity chromatography technology	Choudhury NR (2017)	1
SOX2	4	USP7	14	affinity chromatography technology, affinity chromatography technology	Cox JL (2013), Cox JL (2013)	2
TRIM63	0	TRIM54	1	two hybrid, pull down	Centner T (2001), Centner T (2001)	2
EGLN3	0	KEAP1	0	affinity chromatography technology	Rodriguez J (2016)	1
BMPR1B	3	TRAF6	0	affinity chromatography technology	Sorrentino A (2008)	1
SOX2	4	PPIH	1	affinity chromatography technology	Cox JL (2013)	1
OTUB1	0	SMAD3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Herhaus L (2013), Herhaus L (2013), Herhaus L (2013)	3
POU5F1	0	SMC3	16	affinity chromatography technology	Oliviero G (2015)	1
BAG6	2	HUWE1	22	affinity chromatography technology	Rodrigo-Brenni MC (2014)	1
NTRK1	1	NPM1	0	affinity chromatography technology	Emdal KB (2015)	1
MCM2	3	VSIG8	3	affinity chromatography technology	Drissi R (2015)	1
SMURF2	3	ID1	0	enzymatic study, affinity chromatography technology	Kong Y (2011), Kong Y (2011)	2
NTRK1	1	COPS5	0	affinity chromatography technology	Emdal KB (2015)	1
NXF1	0	GRK5	7	affinity chromatography technology	Castello A (2012)	1
PSMD7	1	LRRC15	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MCM4	3	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
CUL3	17	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
CDH1	4	USP8	7	bioid	Guo Z (2014)	1
OTUB1	0	NPM1	0	affinity chromatography technology	Edelmann MJ (2009)	1
LSM4	1	LSM8	0	affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology	Eystathioy T (2002), Havugimana PC (2012), Lehner B (2004), Lehner B (2004), Boldt K (2016)	5
USP15	4	UBE2S	2	enzymatic study	Bremm A (2010)	1
BTRC	1	NFE2L1	4	affinity chromatography technology, bioid	Coyaud E (2015), Coyaud E (2015)	2
CTNNB1	30	USP4	3	affinity chromatography technology, affinity chromatography technology	Yun SI (2015), Yun SI (2015)	2
UBC	7	PPIH	1	affinity chromatography technology	Matsumoto M (2005)	1
DFFA	0	USP15	4	affinity chromatography technology	Ewing RM (2007)	1
FN1	17	KRT81	1	affinity chromatography technology	Humphries JD (2009)	1
HIST2H2AC	1	UBC	7	pull down, pull down	Long L (2014), Zhang X (2017)	2
USP7	14	LMNA	2	affinity chromatography technology	Bhattacharya S (2015)	1
COPS5	0	CAND1	2	biochemical, affinity chromatography technology	Bornstein G (2006), Bennett EJ (2010)	2
ZC3H13	8	MED4	2	affinity chromatography technology	Malovannaya A (2010)	1
TP53	0	HNRNPL	3	affinity chromatography technology	Horikawa I (2014)	1
TRIM25	5	ECHS1	2	affinity chromatography technology	Choudhury NR (2017)	1
COPS5	0	MCM7	5	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	HNRNPL	3	affinity chromatography technology	Emdal KB (2015)	1
NPM1	0	HIST2H2AC	1	pull down	Swaminathan V (2005)	1
ATL3	0	USP15	4	affinity chromatography technology	Hein MY (2015)	1
MCM4	3	USP15	4	affinity chromatography technology	Boldt K (2016)	1
MKNK2	1	WWP2	7	affinity chromatography technology	Hein MY (2015)	1
UBE2E3	0	UBC	7	enzymatic study	Sheng Y (2012)	1
FN1	17	FERMT3	4	affinity chromatography technology	Humphries JD (2009)	1
USP15	4	USP7	14	enzymatic study	Loch CM (2012)	1
NXF1	0	USP14	1	affinity chromatography technology	Castello A (2012)	1
EGLN3	0	BIRC3	1	affinity chromatography technology	Fu J (2016)	1
TRIM25	5	EPS15L1	1	affinity chromatography technology	Choudhury NR (2017)	1
SEM1	0	USP14	1	affinity chromatography technology	Besche HC (2014)	1
NTRK1	1	SMC1A	15	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	UCHL1	1	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	USP14	1	affinity chromatography technology	Choudhury NR (2017)	1
CUL4B	8	HIST2H2BE	1	affinity chromatography technology	Bennett EJ (2010)	1
CYLD	2	LGALS7	0	affinity chromatography technology	Elliott PR (2016)	1
BMPR1B	3	SMAD6	9	affinity chromatography technology, affinity chromatography technology	Itoh F (2001), Hata A (1998)	2
SART3	2	PRPF31	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Das T (2017), Huttlin EL (2017)	3
SMURF2	3	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang L (2013), Zhou F (2017), Zhou F (2017)	3
COPS5	0	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
MED4	2	BAG6	2	affinity chromatography technology	Lambert JP (2015)	1
NTRK1	1	SMC3	16	affinity chromatography technology	Emdal KB (2015)	1
RNF126	2	SART3	2	affinity chromatography technology	OConnor HF (2015)	1
USP28	3	USP51	1	enzymatic study	Loch CM (2012)	1
CDK11A	1	USP15	4	affinity chromatography technology	Boldt K (2016)	1
CUL4B	8	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
HNRNPL	3	SMURF1	4	affinity chromatography technology	Fei T (2017)	1
MCM2	3	MYH4	6	affinity chromatography technology	Drissi R (2015)	1
ALDOA	0	CKB	1	biochemical	Wan C (2015)	1
SMAD2	5	SMAD6	9	affinity chromatography technology	Topper JN (1997)	1
NXF1	0	MCM4	3	affinity chromatography technology	Castello A (2012)	1
CYLD	2	UBE2S	2	enzymatic study	Bremm A (2010)	1
MCM4	3	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
USP7	14	UBE2S	2	enzymatic study	Bremm A (2010)	1
SMAD7	1	CDH1	4	affinity chromatography technology	Tang Y (2008)	1
GTF3C2	2	SPAG9	5	affinity chromatography technology	Boldt K (2016)	1
GTF3C4	0	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
USP15	4	SELENBP1	2	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	OTUB1	0	affinity chromatography technology	Emdal KB (2015)	1
USP4	3	MEPCE	1	affinity chromatography technology	Sowa ME (2009)	1
USP21	2	USP51	1	enzymatic study	Loch CM (2012)	1
USP8	7	UBC	7	enzymatic study, unspecified method, enzymatic study, x-ray crystallography, enzymatic study, enzymatic study, pull down	Faesen AC (2011), Ernst A (2013), Row PE (2007), Ernst A (2013), Wauer T (2015), Reincke M (2015), Kwasna D (2018)	7
UBC	7	NPM1	0	affinity chromatography technology, pull down	Matsumoto M (2005), Koike A (2010)	2
NTRK1	1	MCM4	3	affinity chromatography technology	Emdal KB (2015)	1
TP53	0	SOX4	5	pull down, affinity chromatography technology, affinity chromatography technology	Pan X (2009), Pan X (2009), Pan X (2009)	3
WWP2	7	HIST2H2BE	1	affinity chromatography technology	Chaudhary N (2014)	1
EPS15L1	1	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
COPS5	0	UCHL3	1	affinity chromatography technology	Sowa ME (2009)	1
SMAD3	1	ANK3	16	two hybrid	Colland F (2004)	1
MCM2	3	TRIM25	5	affinity chromatography technology	Drissi R (2015)	1
USP21	2	UCHL3	1	enzymatic study	Loch CM (2012)	1
LMNA	2	USP15	4	bioid	Roux KJ (2012)	1
USP7	14	TRAF6	0	pull down, affinity chromatography technology, enzymatic study	Zapata JM (2001), Daubeuf S (2009), Bremm A (2010)	3
UBC	7	HNRNPL	3	affinity chromatography technology	Matsumoto M (2005)	1
USP21	2	BAP1	4	enzymatic study	Loch CM (2012)	1
SMAD7	1	SMURF1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Asano Y (2004), Yamaguchi T (2006), Komuro A (2004), Ebisawa T (2001), Ebisawa T (2001), Al-Salihi MA (2012), Suzuki C (2002), Aragon E (2012), Aragon E (2012), Tajima Y (2003), Fei C (2013), Fei C (2014), Wan L (2011), Elkouris M (2016)	14
CUL3	17	PRPF31	0	affinity chromatography technology	Bennett EJ (2010)	1
SMAD1	0	SMAD7	1	affinity chromatography technology	Yan X (2016)	1
TRIM63	0	USP33	1	enzymatic study	Loch CM (2012)	1
MED4	2	CYLD	2	bioid	Lambert JP (2015)	1
SMAD2	5	SMAD7	1	genetic interference, pull down, affinity chromatography technology	Lebrun JJ (1999), Zhang S (2007), Yan X (2016)	3
MCM6	5	KIAA1468	5	affinity chromatography technology	Boldt K (2016)	1
SPAG9	5	USP15	4	affinity chromatography technology	Boldt K (2016)	1
GTF3C4	0	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
SMAD7	1	TP53	0	affinity chromatography technology	Zhang S (2006)	1
USP7	14	USP14	1	affinity chromatography technology	Sowa ME (2009)	1
PLK1	0	HSF1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology	Lee YJ (2008), Lee YJ (2008), Boldt K (2016)	3
USP14	1	UBC	7	unspecified method, pull down, enzymatic study, pull down, pull down	Ernst A (2013), Phillips AH (2013), Flierman D (2016), Zhang X (2017), Kwasna D (2018)	5
NTRK1	1	RNF40	11	affinity chromatography technology	Emdal KB (2015)	1
USP21	2	RBCK1	0	two hybrid	Hayes SD (2012)	1
SMURF1	4	HIST2H2BE	1	affinity chromatography technology	Xie Y (2013)	1
SPAG9	5	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
LSM8	0	FERMT3	4	two hybrid	Lehner B (2004)	1
NTRK1	1	SORT1	1	affinity chromatography technology	Emdal KB (2015)	1
SMAD7	1	SMAD3	1	genetic interference, genetic interference, affinity chromatography technology, protein complementation assay	Datta PK (2000), Lebrun JJ (1999), Yan X (2016), Yan X (2016)	4
TRIM21	0	UBC	7	enzymatic study	McEwan WA (2013)	1
BIRC3	1	USP7	14	affinity chromatography technology	Goncharov T (2013)	1
TRIM63	0	BAP1	4	enzymatic study	Loch CM (2012)	1
MED4	2	TRIM25	5	bioid	Lambert JP (2015)	1
TRAF6	0	YOD1	0	two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Schimmack G (2017), Schimmack G (2017), Schimmack G (2017), Schimmack G (2017), Schimmack G (2017)	5
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
MCM2	3	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	CKB	1	affinity chromatography technology	Emdal KB (2015)	1
HUWE1	22	ALDOA	0	affinity chromatography technology	Thompson JW (2014)	1
SORT1	1	WWP2	7	affinity chromatography technology	Hein MY (2015)	1
TRIM21	0	RBCK1	0	two hybrid	Woodsmith J (2012)	1
SMAD1	0	PSMD11	0	two hybrid	Colland F (2004)	1
MED4	2	KEAP1	0	bioid	Lambert JP (2015)	1
USP28	3	UCHL3	1	enzymatic study	Loch CM (2012)	1
MDM2	2	SOX4	5	affinity chromatography technology	Pan X (2009)	1
MDM2	2	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
CUL3	17	MCM6	5	affinity chromatography technology	Bennett EJ (2010)	1
SMAD3	1	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Yan X (2009), Tang Y (2003), Tang Y (2003), Herhaus L (2015)	4
FN1	17	SMAD4	9	two hybrid	Wang J (2011)	1
TRIM54	1	STAM	3	enzymatic study	Loch CM (2012)	1
BMPR1B	3	SMURF1	4	affinity chromatography technology	Murakami G (2003)	1
SMAD2	5	SMURF2	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin X (2000), Lin X (2000), Bonni S (2001), Nakano A (2009), Komuro A (2004), Zhang Y (2001), Zhang Y (2001), Runyan CE (2009), Runyan CE (2009), Chong PA (2010), Brown KA (2008), Colland F (2004), Colland F (2004), Zhang Y (2017), Zhou F (2017), Zhou F (2017)	16
EPS15L1	1	SOX4	5	affinity chromatography technology	Boldt K (2016)	1
ACVR1	4	SMAD1	0	affinity chromatography technology, affinity chromatography technology	Pardali E (2000), Macias-Silva M (1998)	2
HNRNPL	3	SMURF2	3	affinity chromatography technology	Fei T (2017)	1
CYLD	2	TRAF6	0	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kovalenko A (2003), Bremm A (2010), Wu J (2015), Wu J (2015)	4
BTRC	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down	Inuzuka H (2010), Inuzuka H (2010), Inuzuka H (2010)	3
NTRK1	1	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Qian X (1998), Borrello MG (1994), Nakamura T (2002), Meakin SO (1999), Koch A (2000), Emdal KB (2015), Emdal KB (2015)	7
SMAD3	1	PSMD11	0	two hybrid	Colland F (2004)	1
SART3	2	USP4	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Song EJ (2010), Song EJ (2010), Song EJ (2010), Song EJ (2010), Zhao B (2012), Park JK (2016), Park JK (2016), Das T (2017), Das T (2017), Kwon SK (2017)	11
EGLN3	0	GTF3C2	2	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	LSM8	0	affinity chromatography technology	Sowa ME (2009)	1
TRIM25	5	BMPR1A	5	affinity chromatography technology	Choudhury NR (2017)	1
USP15	4	SMURF2	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Eichhorn PJ (2012), Iyengar PV (2015), Iyengar PV (2015)	3
TCEAL4	0	USP15	4	affinity chromatography technology	Hein MY (2015)	1
USP10	2	UBC	7	enzymatic study, unspecified method, pull down	Bomberger JM (2009), Ernst A (2013), Kwasna D (2018)	3
NTRK1	1	GTF3C4	0	affinity chromatography technology	Emdal KB (2015)	1
NPM1	0	NOP53	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
UCHL3	1	YAP1	0	biochemical	Havugimana PC (2012)	1
SMC3	16	WAPL	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schmitz J (2007), Hutchins JR (2010), Nishiyama T (2010), Kueng S (2006), Kueng S (2006), Kueng S (2006), Kueng S (2006), Hein MY (2015), Hein MY (2015)	9
TRIM54	1	USP8	7	enzymatic study	Loch CM (2012)	1
SMC3	16	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
MCM6	5	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
UCHL1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu J (2008), Li L (2010), Ilic A (2017), Ilic A (2017)	4
SPAG9	5	PPP4R2	0	affinity chromatography technology	Boldt K (2016)	1
SMC1A	15	PLK1	0	biochemical, affinity chromatography technology	Wan C (2015), Boldt K (2016)	2
SPAG9	5	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
USP21	2	DDX58	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Fan Y (2014), Fan Y (2014), Fan Y (2014)	3
USP4	3	LSM4	1	affinity chromatography technology	Sowa ME (2009)	1
TP53	0	SMAD2	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Tateossian H (2009), Lu D (2013), Chen TC (2014)	5
UBE2S	2	RBCK1	0	two hybrid	Markson G (2009)	1
IVNS1ABP	0	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
EPS15L1	1	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
TRIM25	5	ZMYM2	5	affinity chromatography technology	Choudhury NR (2017)	1
USP15	4	PLA2G2A	1	enzymatic study	Altun M (2011)	1
RHPN1	2	PPP4R3A	3	affinity chromatography technology	Huttlin EL (2017)	1
USP15	4	YOD1	0	enzymatic study	Loch CM (2012)	1
USP7	14	TRAF4	1	pull down, affinity chromatography technology, affinity chromatography technology	Zapata JM (2001), Yi P (2013), Yi P (2013)	3
NTRK1	1	MCM2	3	affinity chromatography technology	Emdal KB (2015)	1
USP15	4	RNF20	9	affinity chromatography technology	Long L (2014)	1
CUL3	17	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huang X (2016), Huttlin EL (2017)	3
USP15	4	SENP3	1	enzymatic study	Loch CM (2012)	1
USP15	4	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
USP15	4	KRT33B	1	affinity chromatography technology	Sowa ME (2009)	1
CUL3	17	SMC3	16	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	PPP4R3A	3	affinity chromatography technology	Emdal KB (2015)	1
MCM2	3	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
TRAF4	1	SPDL1	2	two hybrid	Rolland T (2014)	1
SENP3	1	MCM7	5	affinity chromatography technology	Wang M (2016)	1
EPS15L1	1	PRPF4	3	biochemical	Kristensen AR (2012)	1
CTNNB1	30	SMURF1	4	affinity chromatography technology, pull down	Boonanantanasarn K (2015), Boonanantanasarn K (2015)	2
TRIM5	4	PSMD7	1	affinity chromatography technology	Lukic Z (2011)	1
YAP1	0	USP15	4	affinity chromatography technology	Enzo E (2015)	1
USP15	4	USP33	1	enzymatic study	Loch CM (2012)	1
TGFBR1	2	SMAD2	5	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Razani B (2001), Faresse N (2008), Bai Y (2004), Tang Y (2003), Tang Y (2003), Ding L (2009), Lu D (2013), Herhaus L (2015)	8
USP28	3	BAP1	4	enzymatic study	Loch CM (2012)	1
USP15	4	PHF7	5	two hybrid	Hayes SD (2012)	1
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
SEM1	0	RNF126	2	affinity chromatography technology	Besche HC (2014)	1
PRPF3	3	LSM2	0	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Lu D (2013), Ali A (2013)	4
SART3	2	COPS5	0	biochemical	Kristensen AR (2012)	1
BIRC2	1	USP15	4	affinity chromatography technology	Goncharov T (2013)	1
UBE2S	2	RNF40	11	affinity chromatography technology	Hein MY (2015)	1
SNUPN	2	USP15	4	affinity chromatography technology	Huttlin EL (2015)	1
USP4	3	LSM8	0	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	GAPVD1	6	affinity chromatography technology	Emdal KB (2015)	1
USP15	4	LSM4	1	affinity chromatography technology	Sowa ME (2009)	1
KEAP1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang XJ (2008), Rachakonda G (2008), Rachakonda G (2008), Nioi P (2007), Chew EH (2007), Chew EH (2007), Zhang DD (2005), Furukawa M (2005), Furukawa M (2005), Furukawa M (2005), Zhang DD (2004), Cullinan SB (2004), Kobayashi A (2004), Kobayashi A (2004), McMahon M (2006), Ichikawa T (2009), Lee DF (2009), Wong DP (2010), Wong DP (2010), Lau A (2010), Lau A (2010), Hur W (2010), Bennett EJ (2010), Yao JW (2012), Li Y (2012), Choo YY (2012), Kansanen E (2011), Kansanen E (2011), Niture SK (2013), Hast BE (2014), Cleasby A (2014), Kaspar JW (2012), Kaspar JW (2012), Su C (2015), Su C (2015), Huo L (2015), Dubiel D (2015), Lo SC (2006), Wu G (2017), Villeneuve NF (2013), Villeneuve NF (2013), Villeneuve NF (2013), Dong T (2016)	43
MCM6	5	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
USP28	3	STAM	3	enzymatic study	Loch CM (2012)	1
LMNA	2	CTNNB1	30	affinity chromatography technology	Choi J (2004)	1
HUWE1	22	PSMD7	1	affinity chromatography technology	Thompson JW (2014)	1
COPS7B	0	BTRC	1	affinity chromatography technology	Huang X (2016)	1
USP28	3	UBC	7	enzymatic study, enzymatic study, x-ray crystallography, enzymatic study, pull down, enzymatic study, pull down	Loch CM (2012), Zhen Y (2014), Wen Y (2015), Wen Y (2015), Wen Y (2015), Wrigley JD (2017), Kwasna D (2018)	7
HNRNPL	3	USP15	4	affinity chromatography technology	Fei T (2017)	1
RNF26	2	USP15	4	affinity chromatography technology, affinity chromatography technology	Jongsma ML (2016), Jongsma ML (2016)	2
USP21	2	USP7	14	enzymatic study	Loch CM (2012)	1
TRAF6	0	BIRC3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mao AP (2010), Goncharov T (2013), Harikumar KB (2014), Harikumar KB (2014)	4
RNF19B	0	USP15	4	affinity chromatography technology	Huttlin EL (2017)	1
FN1	17	NPM1	0	affinity chromatography technology	Humphries JD (2009)	1
NTRK1	1	RNF20	9	affinity chromatography technology	Emdal KB (2015)	1
USP20	3	UCHL3	1	affinity chromatography technology	Sowa ME (2009)	1
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
EPS15L1	1	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
USP7	14	HUWE1	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Thompson JW (2014), Thompson JW (2014), Hein MY (2015)	4
SMAD3	1	SMURF2	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin X (2000), Lin X (2000), Bonni S (2001), Nakano A (2009), Komuro A (2004), Zhang Y (2001), Zhang Y (2001), Tang LY (2011), Brown KA (2008), Zhang L (2013), Li Y (2017), Zhang Y (2017)	12
SPAG9	5	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
MEPCE	1	PRPF3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Li S (2014), Huttlin EL (2017)	3
MEPCE	1	LSM4	1	affinity chromatography technology	Jeronimo C (2007)	1
NPM1	0	HIST2H2BE	1	pull down, affinity chromatography technology	Swaminathan V (2005), Hein MY (2015)	2
TRIM54	1	JOSD1	1	enzymatic study	Loch CM (2012)	1
BIRC2	1	USP7	14	affinity chromatography technology	Goncharov T (2013)	1
BTRC	1	KEAP1	0	affinity chromatography technology, bioid	Sowa ME (2009), Coyaud E (2015)	2
RNF126	2	SMC1A	15	affinity chromatography technology	OConnor HF (2015)	1
SMAD4	9	SMAD7	1	genetic interference, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lebrun JJ (1999), Moren A (2005), Moren A (2005), Moren A (2005), Zhang S (2007), Yan X (2016)	6
TRIM63	0	USP8	7	enzymatic study	Loch CM (2012)	1
USP4	3	PSMD11	0	two hybrid, affinity chromatography technology, pull down	Zhao B (2012), Zhao B (2012), Zhao B (2012)	3
SART3	2	LSM4	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017), Boldt K (2016)	3
RNF126	2	MCM2	3	affinity chromatography technology	OConnor HF (2015)	1
USP15	4	USP15	4	x-ray crystallography, pull down	Elliott PR (2011), Elliott PR (2011)	2
NXF1	0	WWP2	7	affinity chromatography technology	Castello A (2012)	1
MDM2	2	NPM1	0	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology	Kurki S (2004), Kurki S (2004), Nicholson J (2012), Nicholson J (2012)	4
CUL4B	8	USP4	3	affinity chromatography technology	Bennett EJ (2010)	1
GAPVD1	6	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
SGTB	2	BAG6	2	affinity chromatography technology	Hein MY (2015)	1
USP15	4	PRPF4	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009)	2
OTUB1	0	RNF126	2	two hybrid	Hayes SD (2012)	1
LSM2	0	LSM6	0	biochemical, two hybrid, two hybrid, biochemical, affinity chromatography technology	Havugimana PC (2012), Hegele A (2012), Hegele A (2012), Wan C (2015), Huttlin EL (2017)	5
NTRK1	1	PSMD11	0	affinity chromatography technology	Emdal KB (2015)	1
PSMD7	1	PSMD11	0	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
ATG2B	11	USP15	4	affinity chromatography technology	Boldt K (2016)	1
SELENBP1	2	USP33	1	two hybrid, pull down	Jeong JY (2009), Jeong JY (2009)	2
NTRK1	1	CTNNB1	30	affinity chromatography technology	Emdal KB (2015)	1
USP28	3	USP4	3	enzymatic study	Loch CM (2012)	1
TERF2	2	ZC3H13	8	affinity chromatography technology	Giannone RJ (2010)	1
YAP1	0	CTNNB1	30	affinity chromatography technology	Boldt K (2016)	1
SMAD4	9	SMAD6	9	affinity chromatography technology, affinity chromatography technology	Topper JN (1997), Moren A (2005)	2
EGLN3	0	BIRC2	1	affinity chromatography technology	Fu J (2016)	1
MCM2	3	ADSL	5	affinity chromatography technology	Drissi R (2015)	1
NTRK1	1	SENP3	1	affinity chromatography technology	Emdal KB (2015)	1
USP10	2	PPP4R3A	3	affinity chromatography technology	Huttlin EL (2017)	1
USP21	2	USP20	3	affinity chromatography technology, enzymatic study	Sowa ME (2009), Loch CM (2012)	2
GRK5	7	USP15	4	affinity chromatography technology	Wu Z (2012)	1
CUL4B	8	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Hein MY (2015)	4
PSMB9	0	USP15	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PPP4R2	0	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
SPAG9	5	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
BMPR1A	5	BMPR1B	3	affinity chromatography technology, imaging technique	Gilboa L (2000), Gilboa L (2000)	2
SOX2	4	ANAPC1	1	affinity chromatography technology	Cox JL (2013)	1
PPIH	1	PRPF3	3	two hybrid, two hybrid, affinity chromatography technology	Liu S (2006), Liu S (2006), Boldt K (2016)	3
EGLN3	0	ANAPC1	1	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	VSIG8	3	affinity chromatography technology	Sowa ME (2009)	1
TP53	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li M (2002), Li M (2002), Li M (2002), Li M (2002), Brooks CL (2007), Brooks CL (2007), Becker K (2007), Hu M (2006), Hu M (2006), Sarkari F (2010), Marchenko ND (2007), Epping MT (2011), Qing P (2011), Tang J (2006), Ma J (2010), Dai C (2011), Holowaty MN (2003), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Yi P (2013), Yi P (2013), Zhang J (2014), Fang Z (2013), Ye M (2015), Lim KH (2015), Lim KH (2015), Reddy BA (2014), Reddy BA (2014)	29
NXF1	0	ANAPC1	1	affinity chromatography technology	Castello A (2012)	1
SEM1	0	UBE2G2	0	affinity chromatography technology	Besche HC (2014)	1
PPP4R2	0	USP15	4	affinity chromatography technology	Boldt K (2016)	1
USP20	3	USP33	1	affinity chromatography technology, affinity chromatography technology	Li J (2013), Li J (2013)	2
USP15	4	ACVR1	4	affinity chromatography technology	Herhaus L (2014)	1
NTRK1	1	TRIM46	3	affinity chromatography technology	Emdal KB (2015)	1
YAP1	0	CSTF1	1	affinity chromatography technology	Enzo E (2015)	1
NXF1	0	SENP3	1	affinity chromatography technology	Castello A (2012)	1
TP53	0	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen D (2005), Chen D (2005), Chen D (2005), Chen D (2005), Rolfo A (2012), Rolfo A (2012)	6
NTRK1	1	SART3	2	affinity chromatography technology	Emdal KB (2015)	1
CUL3	17	KRT31	0	affinity chromatography technology	Bennett EJ (2010)	1
PRPF4	3	MEPCE	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Jeronimo C (2007)	2
USP11	3	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Ke JY (2014), Ke JY (2014)	3
USP11	3	IVNS1ABP	0	affinity chromatography technology	Sowa ME (2009)	1
COPS5	0	HIST2H2BE	1	affinity chromatography technology	Bennett EJ (2010)	1
CDH1	4	EPS15L1	1	bioid	Guo Z (2014)	1
NTRK1	1	CUL3	17	affinity chromatography technology	Emdal KB (2015)	1
SPAG9	5	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
TRIM25	5	SENP3	1	affinity chromatography technology	Choudhury NR (2017)	1
TRIM54	1	USP15	4	enzymatic study	Loch CM (2012)	1
MCM2	3	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	UGP2	2	affinity chromatography technology	Emdal KB (2015)	1
SART3	2	UBC	7	affinity chromatography technology	Timani KA (2014)	1
MEPCE	1	UBE2S	2	affinity chromatography technology	Jeronimo C (2007)	1
HUWE1	22	NPM1	0	affinity chromatography technology	Thompson JW (2014)	1
COPS7B	0	USP15	4	affinity chromatography technology	Huang X (2016)	1
MCM2	3	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
HUWE1	22	TUT1	3	affinity chromatography technology	Thompson JW (2014)	1
EGLN3	0	BRAP	0	affinity chromatography technology	Rodriguez J (2016)	1
COPS5	0	SMC3	16	affinity chromatography technology	Bennett EJ (2010)	1
SMAD3	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Charbonney E (2011), Zhou B (2012)	4
HUWE1	22	CKB	1	affinity chromatography technology	Thompson JW (2014)	1
BCR	3	USP15	4	affinity chromatography technology	Boldt K (2016)	1
HUWE1	22	MCM2	3	affinity chromatography technology	Thompson JW (2014)	1
CYLD	2	KRT34	6	affinity chromatography technology	Elliott PR (2016)	1
NOTCH1	25	USP7	14	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
USP4	3	DDX58	3	affinity chromatography technology, affinity chromatography technology	Wang L (2013), Wang L (2013)	2
USP4	3	USP15	4	affinity chromatography technology, enzymatic study, affinity chromatography technology	Zhang L (2012), Loch CM (2012), Das T (2017)	3
LSM6	0	TUT1	3	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	PGAM2	1	affinity chromatography technology	Choudhury NR (2017)	1
MDM2	2	UBE2E2	1	pull down, pull down	David Y (2011), Yamauchi T (2014)	2
TRIM25	5	USP11	3	affinity chromatography technology	Choudhury NR (2017)	1
CAND1	2	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
DDX58	3	UBC	7	pull down, pull down	Feng M (2012), Zeng W (2010)	2
SMAD3	1	USP7	14	affinity chromatography technology, two hybrid	Brown KA (2008), Wang J (2011)	2
PTCH1	8	BTRC	1	affinity chromatography technology	Yamaki Y (2016)	1
EPS15L1	1	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
FN1	17	HNRNPL	3	affinity chromatography technology	Humphries JD (2009)	1
COPS5	0	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
LSM2	0	LSM8	0	two hybrid, two hybrid, biochemical, two hybrid, two hybrid, two hybrid	Lehner B (2004), Lehner B (2004), Havugimana PC (2012), Hegele A (2012), Hegele A (2012), Lehner B (2004)	6
SMAD2	5	SMURF1	4	affinity chromatography technology, affinity chromatography technology, two hybrid	Komuro A (2004), Ito I (2010), Colland F (2004)	3
WWP2	7	NPM1	0	affinity chromatography technology	Chaudhary N (2014)	1
PTCH1	8	SMURF2	3	affinity chromatography technology	Chen XL (2014)	1
JOSD1	1	UBC	7	pull down, x-ray crystallography, enzymatic study, enzymatic study, pull down	Nicastro G (2009), Nicastro G (2009), Seki T (2013), Weeks SD (2011), Kwasna D (2018)	5
UBC	7	PSMD7	1	affinity chromatography technology, pull down	Matsumoto M (2005), Zhang X (2017)	2
MEPCE	1	PRPF31	0	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Huttlin EL (2017)	2
BCR	3	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
UBC	7	RNF126	2	affinity chromatography technology, enzymatic study, pull down	Matsumoto M (2005), Hou X (2012), Lee NS (2017)	3
USP4	3	LSM6	0	affinity chromatography technology	Sowa ME (2009)	1
HUWE1	22	MCM6	5	affinity chromatography technology	Thompson JW (2014)	1
STAM	3	UBC	7	pull down, affinity chromatography technology, x-ray crystallography, pull down, pull down, pull down, unspecified method, pull down, pull down, x-ray crystallography, pull down	Kim MS (2006), Mizuno E (2006), Hong YH (2009), Nathan JA (2013), Nathan JA (2013), Stuible M (2010), Lim J (2011), Baiady N (2016), Kharitidi D (2015), Sundd M (2012), Zhang X (2017)	11
SPAG9	5	KIAA1468	5	affinity chromatography technology	Boldt K (2016)	1
KEAP1	0	UBC	7	affinity chromatography technology, affinity chromatography technology, pull down	Gjyshi O (2015), Su C (2015), Zhang X (2017)	3
NTRK1	1	SBNO1	4	affinity chromatography technology	Emdal KB (2015)	1
SMAD1	0	SMAD4	9	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harada J (2003), Hanai J (1999), Lopez-Rovira T (2002), Kato Y (2002), Wang L (2011), Li L (2004), Hata A (1998), Barrios-Rodiles M (2005), Wu RY (1997), Wu RY (1997), Colland F (2004), Qiu T (2007), Yan X (2016), Zhou F (2017)	14
RNF126	2	MCM4	3	affinity chromatography technology	OConnor HF (2015)	1
USP15	4	MYH2	2	affinity chromatography technology	Sowa ME (2009)	1
SMAD2	5	COPS5	0	two hybrid	Colland F (2004)	1
USP15	4	PLOD2	2	biochemical	Kristensen AR (2012)	1
CDH1	4	NOTCH1	25	bioid	Guo Z (2014)	1
GTF3C4	0	EPS15L1	1	affinity chromatography technology	Boldt K (2016)	1
NXF1	0	ECHS1	2	affinity chromatography technology	Castello A (2012)	1
NXF1	0	YAP1	0	affinity chromatography technology	Castello A (2012)	1
CUL4B	8	NXF1	0	biochemical	Wan C (2015)	1
TRIM25	5	PLK1	0	affinity chromatography technology	Choudhury NR (2017)	1
HIST2H2BE	1	UBC	7	pull down	Long L (2014)	1
FN1	17	BAG6	2	affinity chromatography technology	Humphries JD (2009)	1
TRIM25	5	HUWE1	22	affinity chromatography technology	Choudhury NR (2017)	1
EGLN3	0	ATG2B	11	affinity chromatography technology	Rodriguez J (2016)	1
TP53	0	LMNA	2	affinity chromatography technology	Horikawa I (2014)	1
OTUB1	0	UBE2E2	1	affinity chromatography technology, affinity chromatography technology	Scholz CC (2016), Huttlin EL (2017)	2
ATL3	0	PHB2	1	biochemical	Wan C (2015)	1
CUL3	17	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Bish RA (2007), Wu K (2016)	4
BIRC2	1	UBC	7	pull down, pull down, pull down, pull down, enzymatic study	Dynek JN (2010), Gyrd-Hansen M (2008), Gyrd-Hansen M (2008), Komander D (2009), Sakamoto H (2015)	5
HNRNPL	3	USP14	1	affinity chromatography technology	Fei T (2017)	1
NTRK1	1	USP15	4	affinity chromatography technology	Emdal KB (2015)	1
USP15	4	RNF40	11	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Long L (2014)	2
UCHL3	1	UBE2S	2	enzymatic study	Bremm A (2010)	1
EGLN3	0	IRS2	6	affinity chromatography technology	Rodriguez J (2016)	1
NTRK1	1	PRPF3	3	affinity chromatography technology	Emdal KB (2015)	1
TP53	0	GTF3C4	0	affinity chromatography technology	Fogeron ML (2013)	1
RORC	4	USP15	4	affinity chromatography technology	He Z (2016)	1
NXF1	0	ADSL	5	affinity chromatography technology	Castello A (2012)	1
CTNNB1	30	COPS5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2009), Jumpertz S (2014), Jumpertz S (2014)	3
FN1	17	MCM2	3	affinity chromatography technology	Humphries JD (2009)	1
PRPF3	3	LSM8	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
NTRK1	1	EPS15L1	1	affinity chromatography technology	Emdal KB (2015)	1
USP15	4	UCHL3	1	enzymatic study	Loch CM (2012)	1
SMAD3	1	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid	Brown KA (2008), Wu RY (1997), Wu RY (1997)	3
TP53	0	USP15	4	affinity chromatography technology, affinity chromatography technology	Liu WT (2016), Liu WT (2016)	2
USP4	3	RORC	4	affinity chromatography technology	Yang J (2015)	1
USP15	4	CALML3	0	affinity chromatography technology	Sowa ME (2009)	1
SOX2	4	SENP3	1	affinity chromatography technology	Cox JL (2013)	1
TRIM25	5	MDM2	2	affinity chromatography technology	Choudhury NR (2017)	1
TP53	0	USP10	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology	Yuan J (2010), Yuan J (2010), Yuan J (2010), Yuan J (2010), Oi N (2014), Oi N (2014), Oi N (2014)	7
POU5F1	0	PRPF3	3	affinity chromatography technology	Oliviero G (2015)	1
COPS7A	0	BTRC	1	affinity chromatography technology	Huang X (2016)	1
TERF2	2	SMC3	16	affinity chromatography technology	Giannone RJ (2010)	1
WWP2	7	SMAD7	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Soond SM (2011), Soond SM (2011), Soond SM (2011), Al-Salihi MA (2012)	4
USP10	2	PPP4R2	0	affinity chromatography technology	Huttlin EL (2017)	1
SOX2	4	LSM8	0	affinity chromatography technology	Cox JL (2013)	1
NXF1	0	EPS15L1	1	affinity chromatography technology	Castello A (2012)	1
CUL3	17	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huang X (2016), Huttlin EL (2017)	5
SEM1	0	BAG6	2	affinity chromatography technology	Besche HC (2014)	1
TRIM25	5	PPP4R2	0	affinity chromatography technology	Choudhury NR (2017)	1
HNRNPL	3	ANK3	16	affinity chromatography technology	Fei T (2017)	1
MCM6	5	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
TRIM25	5	GTF3C2	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	SMAD3	1	affinity chromatography technology	Choudhury NR (2017)	1
CTNNB1	30	POU5F1	0	affinity chromatography technology, affinity chromatography technology	Xu C (2013), Xu C (2013)	2
CUL4B	8	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
USP21	2	SENP3	1	enzymatic study	Loch CM (2012)	1
USP21	2	TRAF6	0	enzymatic study	Bremm A (2010)	1
USP4	3	PLA2G2A	1	enzymatic study	Altun M (2011)	1
RNF20	9	SMURF2	3	affinity chromatography technology, pull down	Blank M (2012), Blank M (2012)	2
USP21	2	JOSD1	1	enzymatic study	Loch CM (2012)	1
UBC	7	MAD1L1	2	pull down	Nathan JA (2013)	1
SMAD6	9	USP11	3	affinity chromatography technology, affinity chromatography technology	Herhaus L (2014), Herhaus L (2014)	2
USP8	7	HIST2H2AC	1	enzymatic study	Yu M (2016)	1
TRIM25	5	HNRNPL	3	affinity chromatography technology	Choudhury NR (2017)	1
CUL3	17	MCM7	5	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Rutz N (2015)	2
USP4	3	HUWE1	22	affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang X (2011), Zhang X (2011), Zhang X (2011)	3
TRIM54	1	USP4	3	enzymatic study	Loch CM (2012)	1
STN1	0	USP15	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MCM2	3	ANK3	16	affinity chromatography technology, affinity chromatography technology	Drissi R (2015), Boldt K (2016)	2
TGFBR1	2	NOTCH1	25	affinity chromatography technology, affinity chromatography technology	Gudey SK (2014), Gudey SK (2014)	2
UBC	7	RNF20	9	affinity chromatography technology	Bish RA (2007)	1
BCR	3	TP53	0	two hybrid, imaging technique	Stelzl U (2005), Chen TC (2014)	2
FERMT3	4	USP15	4	affinity chromatography technology	Hein MY (2015)	1
CYLD	2	MCM7	5	affinity chromatography technology	Elliott PR (2016)	1
UBC	7	PSMD11	0	affinity chromatography technology, pull down	Matsumoto M (2005), Zhang X (2017)	2
EGLN3	0	PSMD11	0	affinity chromatography technology	Rodriguez J (2016)	1
TRIM25	5	TGFBR1	2	affinity chromatography technology	Choudhury NR (2017)	1
MDM2	2	CDH1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Yang JY (2006), Yang JY (2006), Yang JY (2006), Adhikary A (2014)	4
CDH1	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Davies G (2001), Kucerova D (2001), Oyama T (1994), Hazan RB (1997), Kinch MS (1995), Jiang MC (2002), Hazan RB (1998), Bonvini P (2001), Li Y (1998), Wendeler MW (2004), Shibata T (2003), Piedra J (2003), Oneyama C (2002), Navarro P (1993), Takahashi K (1997), Dobrosotskaya IY (2000), Dobrosotskaya IY (2000), Geng L (2000), Shibamoto S (1995), Rao RK (2002), Rao RK (2002), Huber AH (2001), Schmeiser K (1999), Pai R (2008), Tu LC (2007), Tu LC (2007), Smyth D (2012), Xue B (2005), Xue B (2005), Catimel B (2005), Huang Z (2012), Yan HX (2006), Yan HX (2006), Figueiredo J (2013), Ponce E (2014), Ponce E (2014), Ponce E (2014), Ribeiro AS (2013), Pinheiro H (2012), Geng F (2012), Lee HK (2007), Guo Z (2014)	42
SMAD6	9	TGFBR1	2	affinity chromatography technology, affinity chromatography technology	Hata A (1998), Kamiya Y (2010)	2
USP15	4	ADSL	5	affinity chromatography technology	Sowa ME (2009)	1
EGLN3	0	MCM7	5	affinity chromatography technology	Rodriguez J (2016)	1
SOX2	4	MEPCE	1	affinity chromatography technology	Cox JL (2013)	1
MDM2	2	UBE2E3	0	pull down, pull down	David Y (2011), Yamauchi T (2014)	2
LSM6	0	PRPF3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
TRIM25	5	ATL3	0	affinity chromatography technology	Choudhury NR (2017)	1
SMAD1	0	UCHL3	1	affinity chromatography technology, affinity chromatography technology	Kim JY (2011), Kim JY (2011)	2
USP28	3	USP14	1	enzymatic study	Loch CM (2012)	1
WWP2	7	SMAD2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Soond SM (2011), Soond SM (2011), Brown KA (2008)	3
USP21	2	USP33	1	enzymatic study	Loch CM (2012)	1
PRPF3	3	LSM4	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
MCM4	3	MCM2	3	pull down, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), You Z (1999), Ishimi Y (1996), Tan BC (2006), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Drissi R (2015), Boldt K (2016)	11
NXF1	0	DFFA	0	affinity chromatography technology	Castello A (2012)	1
TGFBR1	2	SMURF1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koinuma D (2003), Ebisawa T (2001), Murakami G (2003)	3
MCM2	3	MCM6	5	two hybrid, pull down, pull down, two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, biochemical, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Yabuta N (2003), Yabuta N (2003), Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), You Z (1999), You Z (2002), Havugimana PC (2012), Kristensen AR (2012), Rolland T (2014), Wan C (2015), Hein MY (2015), Drissi R (2015), Boldt K (2016)	15
USP15	4	LSM2	0	affinity chromatography technology	Sowa ME (2009)	1
SOX2	4	LSM6	0	affinity chromatography technology	Cox JL (2013)	1
USP15	4	PSMD7	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015)	2
EGLN3	0	CYLD	2	affinity chromatography technology	Rodriguez J (2016)	1
HIST2H2AC	1	USP15	4	affinity chromatography technology	Long L (2014)	1
USP21	2	USP15	4	enzymatic study, enzymatic study	Loch CM (2012), Loch CM (2012)	2
TRIM25	5	WEE1	2	affinity chromatography technology	Choudhury NR (2017)	1
YAP1	0	PHB2	1	affinity chromatography technology	Enzo E (2015)	1
EGLN3	0	SMC3	16	affinity chromatography technology	Rodriguez J (2016)	1
ACVR1	4	BMPR1A	5	fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology	Lavery K (2008), Lavery K (2008), Huttlin EL (2015), Huttlin EL (2017)	4
FN1	17	MCM7	5	affinity chromatography technology	Humphries JD (2009)	1
UBE2G2	0	RNF26	2	two hybrid	van Wijk SJ (2009)	1
GTF3C4	0	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
COPS5	0	PRPF31	0	affinity chromatography technology	Bennett EJ (2010)	1
SMURF1	4	USP15	4	affinity chromatography technology	Xie Y (2013)	1
LSM4	1	LSM6	0	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Eystathioy T (2002), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	4
OTUB1	0	UBE2E3	0	affinity chromatography technology, affinity chromatography technology	Scholz CC (2016), Huttlin EL (2017)	2
TRAF6	0	PSMD7	1	affinity chromatography technology	Bouwmeester T (2004)	1
TRIM25	5	BIRC2	1	affinity chromatography technology	Choudhury NR (2017)	1
FHL1	1	SMAD4	9	pull down, affinity chromatography technology, affinity chromatography technology	Ding L (2009), Ding L (2009), Ding L (2009)	3
NTRK1	1	PLK1	0	affinity chromatography technology	Emdal KB (2015)	1
USP15	4	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
BAP1	4	PSMD7	1	affinity chromatography technology	Hauri S (2016)	1
CUL4B	8	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Bennett EJ (2010), Bennett EJ (2010), Hein MY (2015)	6
NTRK1	1	ADSL	5	affinity chromatography technology	Emdal KB (2015)	1
YOD1	0	BIRC3	1	two hybrid	Schimmack G (2017)	1
EGLN3	0	RNF40	11	affinity chromatography technology	Rodriguez J (2016)	1
SMAD6	9	BMPR1A	5	affinity chromatography technology	Kamiya Y (2010)	1
CUL3	17	CTNNB1	30	affinity chromatography technology	Bennett EJ (2010)	1
FN1	17	KRT31	0	affinity chromatography technology	Humphries JD (2009)	1
RNF20	9	RNF40	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Zhang F (2011), Jaeaeskelaeinen T (2011), Jaeaeskelaeinen T (2011), Moyal L (2011), Moyal L (2011), Zhu B (2005), Kim J (2009), Bedi U (2015), Klement K (2014), Duan Y (2016), Duan Y (2016), Foglizzo M (2016)	12
USP15	4	PPIH	1	affinity chromatography technology	Sowa ME (2009)	1
PRPF4	3	PRPF3	3	affinity chromatography technology, two hybrid, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Liu S (2006), Liu S (2006), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	8
PTCH1	8	TMEM132A	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP21	2	TRIM5	4	two hybrid	Hayes SD (2012)	1
SEM1	0	PSMD7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Baillat D (2005), Wei SJ (2008), Wei SJ (2008)	3
SART3	2	LSM8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017), Boldt K (2016)	3
BTRC	1	SMAD4	9	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wan M (2004), Wan M (2004), Yang L (2006), Yang L (2006), Wan M (2005), Liang M (2004), Demagny H (2014), Li D (2015)	8
TRIM63	0	JOSD1	1	enzymatic study	Loch CM (2012)	1
SMURF2	3	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kavsak P (2000), Yan X (2011), Cai Y (2012), Cai Y (2012), Zhang L (2013), Chandhoke AS (2015), Hsu HY (2014)	7
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
CAND1	2	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
BIRC3	1	USP15	4	affinity chromatography technology	Goncharov T (2013)	1
PPIH	1	LSM6	0	affinity chromatography technology	Boldt K (2016)	1
SMURF1	4	TP53	0	affinity chromatography technology	Nie J (2010)	1
DDX58	3	RBCK1	0	affinity chromatography technology	Inn KS (2011)	1
SMC1A	15	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
WWP2	7	UBE2E3	0	pull down	Sheng Y (2012)	1
FN1	17	PHB2	1	affinity chromatography technology	Humphries JD (2009)	1
HNRNPL	3	PRPF3	3	affinity chromatography technology	Fei T (2017)	1
NXF1	0	LMNA	2	affinity chromatography technology	Castello A (2012)	1
HNRNPL	3	MAD1L1	2	affinity chromatography technology	Fei T (2017)	1
NXF1	0	NPM1	0	affinity chromatography technology	Castello A (2012)	1
USP15	4	STAM	3	enzymatic study	Loch CM (2012)	1
PTCH1	8	SMURF1	4	affinity chromatography technology	Chen XL (2014)	1
MCM4	3	PPP4R3A	3	affinity chromatography technology	Boldt K (2016)	1
MED4	2	USP15	4	bioid	Lambert JP (2015)	1
NXF1	0	RNF40	11	affinity chromatography technology	Castello A (2012)	1
USP28	3	USP15	4	enzymatic study	Loch CM (2012)	1
EGLN3	0	CAND1	2	affinity chromatography technology	Rodriguez J (2016)	1
SMAD4	9	USP15	4	affinity chromatography technology, affinity chromatography technology	Inui M (2011), Eichhorn PJ (2012)	2
USP51	1	HIST2H2AC	1	affinity chromatography technology, enzymatic study	Wang Z (2016), Wang Z (2016)	2
NTRK1	1	USP10	2	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	PRPF31	0	affinity chromatography technology	Emdal KB (2015)	1
MCM2	3	ALDOA	0	affinity chromatography technology	Drissi R (2015)	1
USP28	3	USP20	3	enzymatic study	Loch CM (2012)	1
BCR	3	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
MCM2	3	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
NXF1	0	BTRC	1	affinity chromatography technology	Castello A (2012)	1
SENP3	1	NPM1	0	affinity chromatography technology, affinity chromatography technology, two hybrid, enzymatic study	Haindl M (2008), Haindl M (2008), Haindl M (2008), Haindl M (2008)	4
NTRK1	1	DFFA	0	affinity chromatography technology	Emdal KB (2015)	1
BAP1	4	HIST2H2AC	1	enzymatic study, affinity chromatography technology, enzymatic study	Scheuermann JC (2010), Lee HS (2014), Sahtoe DD (2016)	3
USP15	4	SOX4	5	affinity chromatography technology	Boldt K (2016)	1
SMURF1	4	RBCK1	0	enzymatic study	Andrews PS (2010)	1
MCM2	3	HIST2H2AC	1	affinity chromatography technology	Drissi R (2015)	1
USP15	4	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	WAPL	1	affinity chromatography technology	Emdal KB (2015)	1
GRK5	7	BCR	3	affinity chromatography technology	Wu Z (2012)	1
EGLN3	0	GTF3C4	0	affinity chromatography technology	Rodriguez J (2016)	1
SMAD3	1	SMURF1	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Komuro A (2004), Colland F (2004), Li Y (2017), Li Y (2017)	4
YAP1	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Zhao B (2010), Zhao B (2010), Vinayagam A (2011), Huttlin EL (2017)	4
EGLN3	0	PLK1	0	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	ALDOA	0	affinity chromatography technology	Sowa ME (2009)	1
USP8	7	HIST2H2BE	1	enzymatic study	Yu M (2016)	1
CUL3	17	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
SHC1	0	USP15	4	affinity chromatography technology	Brehme M (2009)	1
FN1	17	PPIH	1	affinity chromatography technology	Humphries JD (2009)	1
GRK5	7	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
CDH1	4	YAP1	0	bioid	Guo Z (2014)	1
RNF126	2	SMC3	16	affinity chromatography technology	OConnor HF (2015)	1
USP14	1	PSMD7	1	affinity chromatography technology, biochemical, biochemical	Sowa ME (2009), Havugimana PC (2012), Wan C (2015)	3
NXF1	0	RNF144B	0	affinity chromatography technology	Castello A (2012)	1
TRAF6	0	BIRC2	1	affinity chromatography technology, affinity chromatography technology	Mao AP (2010), Hinz M (2010)	2
USP7	14	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, unspecified method, biochemical, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lu X (2007), Becker K (2007), Pereg Y (2006), Hu M (2006), Hu M (2006), Hu M (2006), Hu M (2006), Sarkari F (2010), Sarkari F (2010), Tang J (2006), Tang J (2006), Ma J (2010), Song MS (2008), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Ye M (2015), Lim KH (2015), Reddy BA (2014), Rouge L (2016), Nihira NT (2017), Nihira NT (2017), Mungamuri SK (2016), Mungamuri SK (2016), Sun Y (2017)	25
USP28	3	OTUB1	0	enzymatic study	Loch CM (2012)	1
SMAD7	1	USP15	4	affinity chromatography technology	Eichhorn PJ (2012)	1
GTF3C2	2	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
CAND1	2	PRPF4	3	affinity chromatography technology	Bennett EJ (2010)	1
LMNA	2	NPM1	0	affinity chromatography technology	Depreux FF (2015)	1
USP15	4	LRRC15	2	affinity chromatography technology	Sowa ME (2009)	1
TRIM54	1	SENP3	1	enzymatic study	Loch CM (2012)	1
USP8	7	OTUB1	0	affinity chromatography technology	Soares L (2004)	1
MED4	2	SPAG9	5	bioid	Lambert JP (2015)	1
TRIM25	5	EGLN3	0	affinity chromatography technology	Choudhury NR (2017)	1
TGFBR1	2	USP11	3	affinity chromatography technology	Al-Salihi MA (2012)	1
TRIM25	5	DDX58	3	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Gack MU (2007), Gack MU (2007), Gack MU (2007), Gack MU (2010), Nistal-Villan E (2010), Nistal-Villan E (2010), Inn KS (2011), Inn KS (2011), Maharaj NP (2011), Oshiumi H (2013), Weng L (2014), Xia ZP (2009), Feng M (2012), Gao D (2009), Gao D (2009), Jiang J (2016), Hu Y (2017), Hu Y (2017)	18
LSM6	0	MEPCE	1	affinity chromatography technology	Huttlin EL (2017)	1
USP15	4	CKB	1	affinity chromatography technology	Sowa ME (2009)	1
USP14	1	ECHS1	2	biochemical	Kristensen AR (2012)	1
TRIM25	5	UBE2S	2	biochemical, affinity chromatography technology	Havugimana PC (2012), Choudhury NR (2017)	2
YAP1	0	PLOD2	2	affinity chromatography technology	Enzo E (2015)	1
RORC	4	TP53	0	affinity chromatography technology	Huttlin EL (2017)	1
POU5F1	0	USP7	14	affinity chromatography technology	Oliviero G (2015)	1
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
WWP2	7	SMAD3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, two hybrid	Soond SM (2011), Soond SM (2011), Soond SM (2011), Brown KA (2008), Soond SM (2013), Yu H (2011)	6
EGLN3	0	UBE2G2	0	affinity chromatography technology	Rodriguez J (2016)	1
USP7	14	MCM6	5	affinity chromatography technology	Sowa ME (2009)	1
KRT31	0	JOSD1	1	two hybrid	Rolland T (2014)	1
MEPCE	1	TUT1	3	affinity chromatography technology	Jeronimo C (2007)	1
MCM6	5	SMC1A	15	affinity chromatography technology, affinity chromatography technology	Ryu MJ (2006), Boldt K (2016)	2
RNF19B	0	USP4	3	affinity chromatography technology	Huttlin EL (2017)	1
HUWE1	22	MED4	2	biochemical	Wan C (2015)	1
SEM1	0	CUL4B	8	affinity chromatography technology	Besche HC (2014)	1
SMURF1	4	AXIN1	1	enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Fei C (2013), Fei C (2013), Fei C (2014), Fei C (2014), Fei C (2014)	5
USP15	4	MYH4	6	affinity chromatography technology	Sowa ME (2009)	1
SENP3	1	MAD1L1	2	affinity chromatography technology	Wang M (2016)	1
CAND1	2	SART3	2	affinity chromatography technology	Bennett EJ (2010)	1
MCM7	5	SMC1A	15	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, pull down	Havugimana PC (2012), Ryu MJ (2006), Ryu MJ (2006), Ryu MJ (2006), Ryu MJ (2006), Ryu MJ (2006)	6
MCM4	3	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
SEM1	0	UBC	7	affinity chromatography technology	Besche HC (2014)	1
NOP53	2	MDM2	2	two hybrid	Wang J (2011)	1
PPP4R2	0	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
CYLD	2	PHB2	1	affinity chromatography technology	Elliott PR (2016)	1
SENP3	1	MDM2	2	affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Nishida T (2011), Nishida T (2011), Nishida T (2011), Nishida T (2011)	4
USP8	7	KRT31	0	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	MEPCE	1	affinity chromatography technology	Emdal KB (2015)	1
USP15	4	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
ALDOA	0	PGAM2	1	biochemical	Wan C (2015)	1
MCM4	3	SOX4	5	affinity chromatography technology	Boldt K (2016)	1
EGLN3	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	TRIM5	4	two hybrid	Hayes SD (2012)	1
SART3	2	TUT1	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017)	2
UCHL1	1	CTNNB1	30	affinity chromatography technology	Bheda A (2009)	1
EGLN3	0	BCR	3	affinity chromatography technology	Rodriguez J (2016)	1
CTNNB1	30	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, protein complementation assay, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, enzymatic study, protein complementation assay, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang J (2006), Yang J (2006), Cong F (2003), Kitagawa M (1999), Kitagawa M (1999), Kitagawa M (1999), Hart M (1999), Hart M (1999), Hart M (1999), Su Y (2008), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Liu J (2004), Dorrello NV (2006), Godin JD (2010), Guardavaccaro D (2008), Evrard-Todeschi N (2008), Saha A (2008), Saha A (2008), Chen CH (2012), Wei S (2008), Dehan E (2009), Wang D (2011), Gao D (2011), Li VS (2012), Sahasrabuddhe AA (2014), Mbom BC (2014), Mbom BC (2014), Kovacev J (2014), Gao C (2014), Kluge SF (2013), Chong RA (2014), Herrero-Ruiz J (2014), Zhang L (2012), Coyaud E (2015), Loveless TB (2015), Low TY (2014), Coyaud E (2015), Tseng RC (2015), Wu K (2016), Villalobos V (2010), Pierce NW (2009), Shrestha H (2016), Gu JJ (2016), Vaid M (2011)	46
HNRNPL	3	WWP2	7	affinity chromatography technology	Fei T (2017)	1
NXF1	0	UBC	7	affinity chromatography technology	Castello A (2012)	1
MCM2	3	UGP2	2	affinity chromatography technology	Drissi R (2015)	1
SMAD6	9	SMURF1	4	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology	Komuro A (2004), Ebisawa T (2001), Sangadala S (2007), Lee YS (2011), Lee YS (2011)	5
USP15	4	TRIM21	0	two hybrid, two hybrid	Hayes SD (2012), Rolland T (2014)	2
CDK11A	1	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
GTF3C4	0	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
RBCK1	0	TRAF6	0	affinity chromatography technology	Tian Y (2007)	1
USP15	4	LSM6	0	affinity chromatography technology	Sowa ME (2009)	1
YOD1	0	UBC	7	pull down, enzymatic study, x-ray crystallography, enzymatic study, enzymatic study	Ernst R (2009), Mevissen TE (2013), Mevissen TE (2013), Ernst R (2009), Flierman D (2016)	5
EGLN3	0	RNF126	2	affinity chromatography technology	Rodriguez J (2016)	1
GTF3C4	0	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
SMC1A	15	SMC3	16	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (2002), Lee J (2003), Lee J (2003), Schmiesing JA (1998), Gregson HC (2001), Kueng S (2006), Schmitz J (2007), Schmitz J (2007), Losada A (2000), Kang H (2011), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Boldt K (2016)	15
TRIM25	5	UBE2G2	0	affinity chromatography technology	Choudhury NR (2017)	1
SMAD1	0	USP15	4	affinity chromatography technology, affinity chromatography technology	Inui M (2011), Eichhorn PJ (2012)	2
MCM6	5	SOX4	5	affinity chromatography technology	Boldt K (2016)	1
ATG2B	11	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
USP4	3	PRPF4	3	affinity chromatography technology	Sowa ME (2009)	1
RNF126	2	RNF20	9	affinity chromatography technology	OConnor HF (2015)	1
NTRK1	1	BAG6	2	affinity chromatography technology	Emdal KB (2015)	1
CUL4B	8	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Nathan JA (2013)	2
CUL3	17	CKB	1	affinity chromatography technology	Bennett EJ (2010)	1
PPIH	1	PRPF31	0	two hybrid, two hybrid	Liu S (2006), Liu S (2006)	2
EGLN3	0	USP15	4	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
USP15	4	TRAF4	1	affinity chromatography technology, affinity chromatography technology	Zhang L (2013), Zhang L (2013)	2
STK33	5	USP15	4	affinity chromatography technology, pull down	Azoitei N (2012), Azoitei N (2012)	2
BIRC2	1	BIRC3	1	affinity chromatography technology, affinity chromatography technology	Rajalingam K (2006), Rajalingam K (2006)	2
MCM6	5	MCM7	5	pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), Fujita M (1997), You Z (2002), Havugimana PC (2012), Ryu MJ (2006), Wan C (2015), Hein MY (2015), Boldt K (2016)	10
BAG6	2	WWP2	7	affinity chromatography technology	Rodrigo-Brenni MC (2014)	1
USP15	4	KEAP1	0	enzymatic study	Villeneuve NF (2013)	1
HNRNPL	3	USP10	2	affinity chromatography technology	Fei T (2017)	1
CUL4B	8	SART3	2	affinity chromatography technology	Bennett EJ (2010)	1
TRAF6	0	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, imaging technique	Sorrentino A (2008), Yamashita M (2008), Yamashita M (2008), Yamashita M (2008), Zhang J (2014), Cao Q (2016), Sundar R (2015), Sundar R (2015), Sundar R (2015)	9
BTRC	1	AXIN1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Kitagawa M (1999), Kitagawa M (1999), Li VS (2012), Coyaud E (2015), Coyaud E (2015), Novellasdemunt L (2017)	6
PTCH1	8	WWP2	7	affinity chromatography technology, affinity chromatography technology	Chen XL (2014), Chen XL (2014)	2
IRS2	6	USP15	4	affinity chromatography technology, affinity chromatography technology	Fukushima T (2017), Fukushima T (2017)	2
SOX2	4	SART3	2	affinity chromatography technology	Cox JL (2013)	1
NTRK1	1	TRAF6	0	affinity chromatography technology, enzymatic study, affinity chromatography technology	Jadhav T (2008), Geetha T (2005), Zheng C (2015)	3
EGLN3	0	CTNNB1	30	affinity chromatography technology	Rodriguez J (2016)	1
NOTCH1	25	RNF40	11	affinity chromatography technology	Yatim A (2012)	1
USP8	7	KRT85	5	affinity chromatography technology	Sowa ME (2009)	1
TMEM132A	1	USP15	4	affinity chromatography technology	Hein MY (2015)	1
MCM2	3	KEAP1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Mulvaney KM (2016), Mulvaney KM (2016), Mulvaney KM (2016)	3
KRT31	0	CARD9	3	two hybrid	Rolland T (2014)	1
NPM1	0	USP15	4	affinity chromatography technology	Chen R (2013)	1
NXF1	0	MED4	2	affinity chromatography technology	Castello A (2012)	1
GTF3C2	2	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
MEPCE	1	PPIH	1	affinity chromatography technology	Jeronimo C (2007)	1
MDM2	2	SMURF1	4	pull down, affinity chromatography technology, affinity chromatography technology	Nie J (2010), Nie J (2010), Nie J (2010)	3
FN1	17	UBC	7	affinity chromatography technology	Humphries JD (2009)	1
SMAD3	1	CDK11A	1	affinity chromatography technology	Brown KA (2008)	1
USP21	2	UBE2S	2	enzymatic study	Bremm A (2010)	1
SART3	2	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Sowa ME (2009), Long L (2014), Long L (2014), Long L (2014), Timani KA (2014), Park JK (2016), Zhang Q (2016), Zhang Q (2016), Das T (2017), Das T (2017), Das T (2017), Das T (2017), Huttlin EL (2017)	13
MED4	2	PSMD7	1	bioid	Lambert JP (2015)	1
SENP3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology	Wang M (2016), Wang M (2016)	2
TRIM25	5	ANAPC1	1	affinity chromatography technology	Choudhury NR (2017)	1
MCM2	3	UBC	7	affinity chromatography technology	Drissi R (2015)	1
SMAD3	1	SMAD2	5	affinity chromatography technology, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nakao A (1997), Lebrun JJ (1999), Dumont E (2003), Brown KA (2008), Brown KA (2008), Wu RY (1997), Wu RY (1997), Tang Y (2003), Tang Y (2003), Wang J (2011), Huttlin EL (2015), Huttlin EL (2017)	12
SMAD3	1	YAP1	0	affinity chromatography technology	Alarcon C (2009)	1
UBE2E2	1	CUL3	17	pull down	Plafker KS (2009)	1
AXIN1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, pull down	Li Q (2011), Li Q (2011), He Y (2013), He Y (2013), He Y (2013), He Y (2013)	6
KEAP1	0	NFE2L1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Yu M (2011), Wang W (2006), Wang W (2006), Wang J (2011), Niture SK (2013)	5
AXIN1	1	UBC	7	affinity chromatography technology	Li VS (2012)	1
NXF1	0	USP15	4	affinity chromatography technology	Castello A (2012)	1
USP15	4	TRIM74	0	two hybrid	Hayes SD (2012)	1
USP15	4	PSMD11	0	affinity chromatography technology	Sowa ME (2009)	1
CAND1	2	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
TP53	0	TCEAL4	0	affinity chromatography technology	Fogeron ML (2013)	1
TRIM63	0	OTUB1	0	enzymatic study	Loch CM (2012)	1
MCM7	5	USP15	4	affinity chromatography technology	Boldt K (2016)	1
TRAF6	0	USP4	3	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Xiao N (2011), Xiao N (2011), Xiao N (2011), Xiao N (2011), Zhou F (2012), Zhou F (2012)	6
SMAD6	9	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Herhaus L (2014), Herhaus L (2014), Herhaus L (2014)	3
TRAF6	0	TRAF4	1	affinity chromatography technology, fluorescent resonance energy transfe, imaging technique	Takeshita F (2005), Takeshita F (2005), Chen TC (2014)	3
SEM1	0	PSMD11	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Baillat D (2005), Wei SJ (2008), Krogan NJ (2004), Zhang Y (2014)	4
SMAD7	1	BMPR1A	5	affinity chromatography technology, affinity chromatography technology	Mochizuki T (2004), Kamiya Y (2010)	2
NOTCH1	25	SMC1A	15	affinity chromatography technology	Yatim A (2012)	1
FN1	17	PRPF4	3	affinity chromatography technology	Humphries JD (2009)	1
MED4	2	ADSL	5	bioid	Lambert JP (2015)	1
PSMD11	0	TP53	0	two hybrid	Stelzl U (2005)	1
USP15	4	KRT34	6	affinity chromatography technology	Sowa ME (2009)	1
MCM6	5	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	PRPF4	3	affinity chromatography technology	Emdal KB (2015)	1
USP33	1	TRAF6	0	affinity chromatography technology, affinity chromatography technology	Yasunaga J (2011), Yasunaga J (2011)	2
SOX2	4	ZMYM2	5	affinity chromatography technology	Cox JL (2013)	1
CUL3	17	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
USP15	4	CSTF1	1	affinity chromatography technology	Sowa ME (2009)	1
CYLD	2	PSMD11	0	affinity chromatography technology	Elliott PR (2016)	1
NOTCH1	25	CUL3	17	affinity chromatography technology, affinity chromatography technology	Ren K (2014), Ren K (2014)	2
TRIM25	5	USP7	14	affinity chromatography technology	Choudhury NR (2017)	1
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
PHB2	1	USP15	4	affinity chromatography technology	Ewing RM (2007)	1
TRIM25	5	RBCK1	0	affinity chromatography technology, imaging technique, pull down, enzymatic study	Inn KS (2011), Inn KS (2011), Inn KS (2011), Inn KS (2011)	4
PRPF31	0	CCDC57	8	two hybrid	Rolland T (2014)	1
ATG2B	11	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
CYLD	2	PRPF31	0	affinity chromatography technology	Elliott PR (2016)	1
UBC	7	FHL1	1	affinity chromatography technology	Matsumoto M (2005)	1
COPS5	0	PLK1	0	affinity chromatography technology	Bennett EJ (2010)	1
USP14	1	PSMD11	0	affinity chromatography technology, biochemical	Sowa ME (2009), Wan C (2015)	2
MDM2	2	USP10	2	affinity chromatography technology	Yuan J (2010)	1
TERF2	2	UCHL1	1	affinity chromatography technology, imaging technique	Ilic A (2017), Ilic A (2017)	2
UGP2	2	NUSAP1	0	biochemical	Kristensen AR (2012)	1
PRPF4	3	COPS5	0	affinity chromatography technology	Hein MY (2015)	1
CD40	3	USP15	4	affinity chromatography technology	Ewing RM (2007)	1
BMPR1A	5	OTUB1	0	enzymatic study	Herhaus L (2015)	1
CUL3	17	PRPF4	3	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	NOP53	2	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	SORT1	1	affinity chromatography technology	Rodriguez J (2016)	1
PLOD2	2	NUSAP1	0	biochemical	Kristensen AR (2012)	1
SART3	2	HIST2H2AC	1	pull down, pull down	Long L (2014), Long L (2014)	2
EGLN3	0	BAG6	2	affinity chromatography technology	Rodriguez J (2016)	1
SART3	2	LSM2	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017)	2
SOX2	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cox JL (2013), Xu C (2013), Xu C (2013)	3
TRIM25	5	BCR	3	affinity chromatography technology	Choudhury NR (2017)	1
USP21	2	USP8	7	enzymatic study	Loch CM (2012)	1
CTNNB1	30	USP15	4	affinity chromatography technology, affinity chromatography technology	Greenblatt MB (2016), Greenblatt MB (2016)	2
PTCH1	8	CUL3	17	affinity chromatography technology	Yamaki Y (2016)	1
USP15	4	BTRC	1	affinity chromatography technology	Greenblatt MB (2016)	1
MCM4	3	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
BIRC3	1	RBCK1	0	affinity chromatography technology	Goncharov T (2013)	1
NOP53	2	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Lee S (2012), Lee S (2012), Lee S (2012)	3
EGLN3	0	MCM4	3	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	UBC	7	pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down	Hetfeld BK (2005), Bremm A (2010), Komander D (2009), Loch CM (2012), Herhaus L (2014), Wauer T (2015), Das T (2017), Zhang X (2017), Kwasna D (2018)	9
UBC	7	UCHL1	1	two hybrid, enzymatic study, enzymatic study, x-ray crystallography, pull down, pull down, enzymatic study, pull down, enzymatic study, pull down, enzymatic study, pull down, pull down	Stelzl U (2005), Bremm A (2010), Boudreaux D (2012), Boudreaux DA (2010), Boudreaux DA (2010), Phillips AH (2013), Larsen CN (1998), Duerksen-Hughes PJ (1989), Flierman D (2016), Kwasna D (2018), Lee YC (2017), Lee YC (2017), Hanpude P (2017)	13
COPS7B	0	COPS7A	0	biochemical, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2017)	2
HUWE1	22	PHB2	1	affinity chromatography technology	Thompson JW (2014)	1
FN1	17	USP15	4	affinity chromatography technology	Humphries JD (2009)	1
BTRC	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Xia Y (2009), Verma S (2011)	2
TRIM63	0	USP28	3	enzymatic study	Loch CM (2012)	1
MEPCE	1	LSM2	0	affinity chromatography technology	Jeronimo C (2007)	1
USP4	3	PRPF31	0	affinity chromatography technology	Sowa ME (2009)	1
PSMB9	0	PSMD7	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD2	5	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Xi Y (2013)	3
RNF20	9	HIST2H2AC	1	enzymatic study	Kim J (2011)	1
MCM2	3	SOX4	5	affinity chromatography technology	Boldt K (2016)	1
SMAD4	9	CTNNB1	30	affinity chromatography technology	Tian YC (2002)	1
USP15	4	KRT35	0	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	STAM	3	affinity chromatography technology	Emdal KB (2015)	1
TRIM54	1	USP21	2	enzymatic study	Loch CM (2012)	1
SOX2	4	LSM2	0	affinity chromatography technology	Cox JL (2013)	1
NXF1	0	MCM7	5	affinity chromatography technology	Castello A (2012)	1
USP28	3	USP7	14	enzymatic study	Loch CM (2012)	1
TRIM25	5	ALDOA	0	affinity chromatography technology	Choudhury NR (2017)	1
USP15	4	NUSAP1	0	biochemical	Kristensen AR (2012)	1
BAG6	2	USP15	4	affinity chromatography technology	Hein MY (2015)	1
SART3	2	LSM6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017), Boldt K (2016)	3
USP21	2	CUL3	17	affinity chromatography technology, affinity chromatography technology	Heride C (2016), Heride C (2016)	2
USP15	4	SENP8	0	enzymatic study	Loch CM (2012)	1
TGFBR1	2	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Eichhorn PJ (2012), Zhang L (2013), Herhaus L (2014)	3
PLK1	0	MDM2	2	enzymatic study, affinity chromatography technology, pull down	Dias SS (2009), Dias SS (2009), Dias SS (2009)	3
TRIM25	5	PRPF31	0	affinity chromatography technology	Choudhury NR (2017)	1
EGLN3	0	SMC1A	15	affinity chromatography technology	Rodriguez J (2016)	1
USP21	2	USP4	3	enzymatic study	Loch CM (2012)	1
UCHL3	1	PLA2G2A	1	enzymatic study	Altun M (2011)	1
USP15	4	OTUB1	0	enzymatic study	Loch CM (2012)	1
MED4	2	EPS15L1	1	bioid	Lambert JP (2015)	1
EPS15L1	1	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	MCM7	5	affinity chromatography technology	Emdal KB (2015)	1
FN1	17	PSMD11	0	affinity chromatography technology	Humphries JD (2009)	1
WEE1	2	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
RNF144B	0	UBC	7	enzymatic study	Michel MA (2017)	1
USP15	4	MEPCE	1	affinity chromatography technology	Sowa ME (2009)	1
EGLN3	0	OTUB1	0	affinity chromatography technology	Rodriguez J (2016)	1
UBC	7	RNF19B	0	affinity chromatography technology	Matsumoto M (2005)	1
CD40	3	TRAF4	1	affinity chromatography technology	Werneburg BG (2001)	1
USP15	4	KIAA1468	5	affinity chromatography technology	Boldt K (2016)	1
MED4	2	ATG2B	11	bioid	Lambert JP (2015)	1
USP4	3	TGFBR1	2	pull down, affinity chromatography technology, enzymatic study	Zhang L (2012), Zhang L (2012), Zhang L (2012)	3
DDX58	3	USP15	4	affinity chromatography technology, pull down	Zhang H (2015), Zhang H (2015)	2
HNRNPL	3	HUWE1	22	affinity chromatography technology	Fei T (2017)	1
CUL3	17	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	PPIH	1	affinity chromatography technology	Bennett EJ (2010)	1
TRIM54	1	CARD9	3	two hybrid	Rolland T (2014)	1
PHB2	1	CTNNB1	30	affinity chromatography technology	Ewing RM (2007)	1
LMNA	2	USP20	3	two hybrid	Dittmer TA (2014)	1
CDH1	4	UBC	7	bioid	Guo Z (2014)	1
CD40	3	TRAF6	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Tsukamoto N (1999), Roy N (1997), Davies CC (2005), Pullen SS (1998), Peters AL (2010), Ye H (2002), Deregibus MC (2003), Basaki Y (2002), Zhang W (2010), Zhang W (2010), He B (2010), Hostager BS (2010), Hostager BS (2010), Verstak B (2014)	14
SMURF1	4	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Cui Y (2011), Zhang Y (2017), Zhang Y (2017), Zhang Y (2017), Zhang Y (2017)	5
CD40	3	BIRC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Werneburg BG (2001), Peters AL (2010), Hostager BS (2010), Hostager BS (2010)	4
SMURF2	3	BTRC	1	enzymatic study, affinity chromatography technology	Shukla S (2014), Shukla S (2014)	2
TRPV5	2	USP15	4	affinity chromatography technology	Huttlin EL (2015)	1
ECHS1	2	USP15	4	affinity chromatography technology	Huttlin EL (2015)	1
TRIM63	0	CKB	1	two hybrid	Witt CC (2008)	1
SMAD2	5	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Inui M (2011), Eichhorn PJ (2012), Wijnhoven P (2015)	3
NTRK1	1	MAD1L1	2	affinity chromatography technology	Emdal KB (2015)	1
TRIM63	0	STAM	3	enzymatic study	Loch CM (2012)	1
BAP1	4	ZC3H13	8	biochemical	Yu H (2010)	1
TRIM25	5	BTRC	1	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	ATL3	0	affinity chromatography technology	Emdal KB (2015)	1
PTCH1	8	USP15	4	affinity chromatography technology	Yamaki Y (2016)	1
USP11	3	USP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Zhang L (2012)	3
SPAG9	5	HUWE1	22	biochemical	Kristensen AR (2012)	1
SMAD3	1	SMAD4	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Seoane J (2004), Moren A (2003), Wu JW (2002), Nakao A (1997), Hanai J (1999), Lebrun JJ (1999), Poncelet AC (2001), Jablonska E (2010), Prunier C (2003), Kato Y (2002), Kaimori A (2010), Tang LY (2011), Tang LY (2011), Dupont S (2009), Dupont S (2009), Pardali K (2000), Kardassis D (2000), Xu L (2003), Fu G (2011), Chen W (2007), Kang JM (2012), Gao S (2009), Li H (2009), Li H (2009), Brown KA (2008), Brown KA (2008), Halder SK (2005), Barrios-Rodiles M (2005), Dai F (2007), Dai F (2007), Chacko BM (2004), Chacko BM (2004), Chacko BM (2004), Stroschein SL (1999), Stroschein SL (1999), Stroschein SL (1999), Wu RY (1997), Wu RY (1997), Wu RY (1997), Wu RY (1997), Tomita M (2004), Colland F (2004), Colland F (2004), Tang Y (2003), Ding L (2009), Fattet L (2013), Wang J (2011), Xue J (2014), Ali A (2013), Gao S (2009), Yamakawa N (2002), Yamakawa N (2002), Wang G (2005), Li X (2015), Zhou F (2014), Yang Y (2015), Yan X (2016), Yan X (2016), Wu Y (2017), Wu Y (2017)	60
USP15	4	ANAPC1	1	affinity chromatography technology	Greenblatt MB (2016)	1
TRAF4	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Wang A (2014), Wang A (2014)	2
UBE2S	2	UBC	7	enzymatic study, pull down, x-ray crystallography, enzymatic study, enzymatic study	Bremm A (2010), Wickliffe KE (2011), Wickliffe KE (2011), Kelly A (2014), Michel MA (2017)	5
ID1	0	ZC3H13	8	affinity chromatography technology	Hein MY (2015)	1
MDM2	2	HIST2H2BE	1	pull down, affinity chromatography technology, enzymatic study	Minsky N (2004), Minsky N (2004), Minsky N (2004)	3
PRPF4	3	LSM6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017), Boldt K (2016)	3
USP4	3	PPIH	1	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	ECHS1	2	affinity chromatography technology	Emdal KB (2015)	1
MCM2	3	LGALS7	0	affinity chromatography technology	Drissi R (2015)	1
NPM1	0	TRIM21	0	affinity chromatography technology	Chen R (2013)	1
MCM6	5	PLK1	0	affinity chromatography technology	Boldt K (2016)	1
USP28	3	PLA2G2A	1	enzymatic study	Altun M (2011)	1
MCM4	3	MCM6	5	pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Yabuta N (2003), Kneissl M (2003), Kneissl M (2003), Ishimi Y (1996), You Z (2002), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Boldt K (2016)	10
CAND1	2	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
USP15	4	RBCK1	0	two hybrid	Hayes SD (2012)	1
ACVR1	4	OTUB1	0	enzymatic study	Herhaus L (2015)	1
MKNK2	1	USP15	4	affinity chromatography technology	Hein MY (2015)	1
TRIM25	5	NOP53	2	affinity chromatography technology	Choudhury NR (2017)	1
UGP2	2	PLOD2	2	biochemical	Kristensen AR (2012)	1
UBC	7	BRAP	0	affinity chromatography technology, two hybrid, pull down, pull down, enzymatic study	Bish RA (2007), Fatima S (2015), Zhang X (2017), Shoji S (2017), Shoji S (2017)	5
TP53	0	SMAD1	0	affinity chromatography technology, affinity chromatography technology	Chau JF (2012), Chau JF (2012)	2
TRIM25	5	MCM4	3	affinity chromatography technology	Choudhury NR (2017)	1
USP21	2	TP53	0	enzymatic study	Fernandez-Majada V (2016)	1
USP10	2	WAPL	1	biochemical	Havugimana PC (2012)	1
ATG2B	11	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
HUWE1	22	PPIH	1	affinity chromatography technology	Thompson JW (2014)	1
USP21	2	OTUB1	0	enzymatic study	Loch CM (2012)	1
MDM2	2	UCHL1	1	affinity chromatography technology	Li L (2010)	1
SMAD6	9	ACVR1	4	affinity chromatography technology, affinity chromatography technology	Kamiya Y (2010), Zhang X (2013)	2
UBC	7	ANAPC1	1	pull down	Nathan JA (2013)	1
USP28	3	USP8	7	enzymatic study	Loch CM (2012)	1
SART3	2	MEPCE	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Jeronimo C (2007), Li S (2014), Huttlin EL (2017)	4
NXF1	0	GAPVD1	6	affinity chromatography technology	Castello A (2012)	1
SMAD1	0	YAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography	Alarcon C (2009), Alarcon C (2009), Aragon E (2011), Aragon E (2011), Aragon E (2011)	5
USP15	4	JOSD1	1	enzymatic study	Loch CM (2012)	1
EGLN3	0	GAPVD1	6	affinity chromatography technology	Rodriguez J (2016)	1
PLK1	0	SMC3	16	biochemical	Wan C (2015)	1
GTF3C4	0	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	TMEM132A	1	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	USP4	3	affinity chromatography technology	Emdal KB (2015)	1
PRPF4	3	PPIH	1	affinity chromatography technology, two hybrid, two hybrid, biochemical, two hybrid, two hybrid, affinity chromatography technology	Sowa ME (2009), Liu S (2006), Liu S (2006), Havugimana PC (2012), Hegele A (2012), Hegele A (2012), Boldt K (2016)	7
PLA2G2A	1	BAG6	2	two hybrid	Vinayagam A (2011)	1
UBC	7	BTRC	1	affinity chromatography technology, enzymatic study	Matsumoto M (2005), Kumar KG (2007)	2
CTNNB1	30	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study, unspecified method	Novellasdemunt L (2017), Novellasdemunt L (2017), Novellasdemunt L (2017), Novellasdemunt L (2017)	4
CUL4B	8	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
BRAP	0	USP4	3	two hybrid, affinity chromatography technology, two hybrid	Hayes SD (2012), Hayes SD (2012), Hayes SD (2012)	3
NTRK1	1	CUL4B	8	affinity chromatography technology	Emdal KB (2015)	1
USP21	2	YOD1	0	enzymatic study	Loch CM (2012)	1
LGALS7	0	USP4	3	affinity chromatography technology	Huttlin EL (2017)	1
HUWE1	22	PPP4R3A	3	affinity chromatography technology	Thompson JW (2014)	1
COPS5	0	USP14	1	two hybrid	Wang J (2008)	1
HIST2H2BE	1	USP15	4	affinity chromatography technology, enzymatic study	Long L (2014), Long L (2014)	2
TERF2	2	PLOD2	2	affinity chromatography technology	Giannone RJ (2010)	1
USP15	4	ZC3H13	8	biochemical	Havugimana PC (2012)	1
LSM6	0	LSM8	0	biochemical, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Lehner B (2004), Lehner B (2004), Huttlin EL (2017), Boldt K (2016)	5
UBC	7	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study	Nathan JA (2013), Bish RA (2007), Thompson JW (2014), Kristariyanto YA (2015), Zhang X (2017), Michel MA (2017)	6
TMEM132A	1	WWP2	7	affinity chromatography technology	Hein MY (2015)	1
CYLD	2	NPM1	0	affinity chromatography technology	Elliott PR (2016)	1
MAD1L1	2	USP15	4	two hybrid	Rolland T (2014)	1
SMURF1	4	IVNS1ABP	0	affinity chromatography technology	Xie Y (2013)	1
SPAG9	5	SOX4	5	affinity chromatography technology	Boldt K (2016)	1
GTF3C4	0	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
TRIM25	5	CAND1	2	affinity chromatography technology	Choudhury NR (2017)	1
PRPF3	3	PRPF31	0	two hybrid, two hybrid, biochemical, affinity chromatography technology	Liu S (2006), Liu S (2006), Wan C (2015), Huttlin EL (2017)	4
MCM6	5	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
USP15	4	PPP4R3A	3	affinity chromatography technology	Boldt K (2016)	1
SMAD1	0	SMAD6	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Topper JN (1997), Murakami G (2003), Itoh F (2001), Hata A (1998), Hata A (1998)	5
SEM1	0	USP15	4	affinity chromatography technology	Besche HC (2014)	1
CTNNB1	30	AXIN1	1	pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Hocevar BA (2003), Hino S (2005), Stoothoff WH (2002), Kim MJ (2008), Kitagawa M (1999), Kitagawa M (1999), Arnold HK (2009), Zhang YG (2012), Godin JD (2010), Godin JD (2010), Sue Ng S (2010), Sue Ng S (2010), Tang Y (2008), Li VS (2012), Yamamoto H (2006), Fei C (2013), Hein MY (2015), Kuslansky Y (2016), Novellasdemunt L (2017)	25
USP15	4	UCHL1	1	enzymatic study	Loch CM (2012)	1
YAP1	0	PTCH1	8	pull down	Schuchardt BJ (2014)	1
SPAG9	5	PPP4R3A	3	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	LMNA	2	affinity chromatography technology	Emdal KB (2015)	1
USP20	3	PLK1	0	affinity chromatography technology	Sowa ME (2009)	1
USP21	2	UCHL1	1	affinity chromatography technology, enzymatic study	Sowa ME (2009), Loch CM (2012)	2
NTRK1	1	HUWE1	22	affinity chromatography technology	Emdal KB (2015)	1
SART3	2	PRPF3	3	fluorescent resonance energy transfe, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stanek D (2004), Sowa ME (2009), Song EJ (2010), Song EJ (2010), Huttlin EL (2017), Boldt K (2016)	6
MCM2	3	HIST2H2BE	1	affinity chromatography technology	Drissi R (2015)	1
MDM2	2	RNF126	2	two hybrid	Woodsmith J (2012)	1
EPS15L1	1	HSF1	1	affinity chromatography technology	Boldt K (2016)	1
USP15	4	PGAM2	1	affinity chromatography technology	Sowa ME (2009)	1
TRAF6	0	SMURF1	4	genetic interference	Li S (2010)	1
SPAG9	5	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	ALDOA	0	affinity chromatography technology	Emdal KB (2015)	1
MDM2	2	USP15	4	pull down	Liu WT (2016)	1
GTF3C4	0	GAPVD1	6	affinity chromatography technology	Boldt K (2016)	1
OTUB1	0	UBC	7	enzymatic study, enzymatic study, x-ray crystallography, unspecified method, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, x-ray crystallography, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down	Wang T (2009), Bremm A (2010), Juang YC (2012), Ernst A (2013), Ernst A (2013), Nakasone MA (2013), Wiener R (2013), Edelmann MJ (2009), Bish RA (2007), Mevissen TE (2013), Juang YC (2012), Herhaus L (2013), Ernst A (2013), Herhaus L (2015), Herhaus L (2015), Herhaus L (2015), Wauer T (2015), Michel MA (2015), Kristariyanto YA (2015), Scholz CC (2016), Scholz CC (2016), Altun M (2015), Flierman D (2016), Castaneda CA (2016), Zhang X (2017), Kwasna D (2018)	26
SNUPN	2	RNF126	2	two hybrid	Vinayagam A (2011)	1
HMG20B	2	USP15	4	biochemical	Havugimana PC (2012)	1
CUL4B	8	TP53	0	affinity chromatography technology	Thirunavukarasou A (2014)	1
GTF3C4	0	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
UBC	7	PRPF4	3	affinity chromatography technology	Matsumoto M (2005)	1
TRIM63	0	USP15	4	enzymatic study	Loch CM (2012)	1
NOP53	2	USP15	4	affinity chromatography technology	Wang P (2016)	1
TRIM54	1	OTUB1	0	enzymatic study	Loch CM (2012)	1
LMNA	2	HNRNPL	3	affinity chromatography technology	Depreux FF (2015)	1
USP15	4	USP20	3	enzymatic study	Loch CM (2012)	1
USP15	4	USP8	7	enzymatic study	Loch CM (2012)	1
SBNO1	4	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
PLK1	0	EPS15L1	1	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Boldt K (2016)	2
PLK1	0	WEE1	2	enzymatic study	Watanabe N (2004)	1
NOTCH1	25	CAND1	2	affinity chromatography technology	Yatim A (2012)	1
TRIM63	0	USP21	2	enzymatic study	Loch CM (2012)	1
PRPF4	3	LSM2	0	affinity chromatography technology	Sowa ME (2009)	1
WEE1	2	MCM4	3	affinity chromatography technology	Boldt K (2016)	1
BMPR1A	5	SMAD1	0	enzymatic study	Kretzschmar M (1997)	1
UBE2G2	0	MDM2	2	two hybrid	van Wijk SJ (2009)	1
USP15	4	USP11	3	affinity chromatography technology	Sowa ME (2009)	1
SOX2	4	PRPF4	3	affinity chromatography technology	Cox JL (2013)	1
NTRK1	1	PSMD7	1	affinity chromatography technology	Emdal KB (2015)	1
NOTCH1	25	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down	Jin YH (2009), Jin YH (2009), Jin YH (2009)	3
SART3	2	HIST2H2BE	1	pull down, pull down	Long L (2014), Long L (2014)	2
TGFBR1	2	SMAD4	9	biochemical, affinity chromatography technology	Razani B (2001), Barrios-Rodiles M (2005)	2
SMURF1	4	SMAD1	0	enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, pull down, unspecified method, two hybrid, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Sangadala S (2006), Komuro A (2004), Tian M (2011), Tian M (2011), Tian M (2011), Sapkota G (2007), Sapkota G (2007), Li L (2004), Alarcon C (2009), Aragon E (2011), Aragon E (2011), Aragon E (2011), Aragon E (2011), Gao S (2009), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Sangadala S (2007), Colland F (2004), Cao Y (2014), Cao Y (2014), Sangadala S (2007), Gao S (2009), Wan L (2011), Wan L (2011), Zhang Y (2017), Zhang Y (2017)	28
TRIM63	0	USP7	14	enzymatic study	Loch CM (2012)	1
MCM2	3	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
DFFA	0	CKB	1	biochemical	Kristensen AR (2012)	1
HMG20B	2	HNRNPL	3	two hybrid	Stelzl U (2005)	1
CUL4B	8	KRT85	5	affinity chromatography technology	Bennett EJ (2010)	1
PRPF3	3	TUT1	3	affinity chromatography technology	Huttlin EL (2017)	1
TP53	0	OTUB1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Sun XX (2011), Sun XX (2011), Sun XX (2011), Li Y (2014), Fernandez-Majada V (2016)	5
USP15	4	ZMYM2	5	biochemical	Havugimana PC (2012)	1
USP15	4	KRT31	0	affinity chromatography technology	Sowa ME (2009)	1
USP28	3	UCHL1	1	enzymatic study	Loch CM (2012)	1
TRIM54	1	LSM2	0	two hybrid	Rolland T (2014)	1
SOX2	4	TUT1	3	affinity chromatography technology	Cox JL (2013)	1
HUWE1	22	MDM2	2	affinity chromatography technology, enzymatic study	Kurokawa M (2013), Kurokawa M (2013)	2
UBC	7	BCR	3	affinity chromatography technology, two hybrid	Chen R (2013), Chen R (2013)	2
TRAF6	0	TRIM25	5	two hybrid	Woodsmith J (2012)	1
OTUB1	0	TRAF6	0	affinity chromatography technology, enzymatic study	Li S (2010), Bremm A (2010)	2
UBC	7	USP4	3	affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down	Matsumoto M (2005), Faesen AC (2011), Song EJ (2010), Clerici M (2014), Kwasna D (2018)	5
TRIM17	5	TRAF6	0	two hybrid	Woodsmith J (2012)	1
CYLD	2	BIRC2	1	affinity chromatography technology	Elliott PR (2016)	1
BIRC3	1	OTUB1	0	affinity chromatography technology	Goncharov T (2013)	1
HUWE1	22	CUL4B	8	affinity chromatography technology, affinity chromatography technology, enzymatic study	Yi J (2015), Yi J (2015), Yi J (2015)	3
USP4	3	LSM2	0	affinity chromatography technology	Sowa ME (2009)	1
UBE2G2	0	UBC	7	x-ray crystallography, pull down, pull down	Bocik WE (2011), Bocik WE (2011), Reyes LF (2006)	3
USP15	4	UGP2	2	biochemical	Kristensen AR (2012)	1
SPAG9	5	ATG2B	11	affinity chromatography technology	Boldt K (2016)	1
FHL1	1	SMAD2	5	pull down, affinity chromatography technology, affinity chromatography technology	Ding L (2009), Ding L (2009), Ding L (2009)	3
HNRNPL	3	UBE2E2	1	affinity chromatography technology	Fei T (2017)	1
NOP53	2	DDX58	3	affinity chromatography technology	Wang P (2016)	1
BCR	3	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
TRAF6	0	USP10	2	affinity chromatography technology	Wang W (2015)	1
UCHL3	1	CDH1	4	enzymatic study	Ponce E (2014)	1
USP8	7	PLA2G2A	1	enzymatic study	Altun M (2011)	1
GTF3C4	0	USP15	4	affinity chromatography technology	Boldt K (2016)	1
POU5F1	0	GTF3C2	2	affinity chromatography technology	Oliviero G (2015)	1
NTRK1	1	BCR	3	affinity chromatography technology	Emdal KB (2015)	1
HUWE1	22	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Thompson JW (2014), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017)	4
USP15	4	AXIN1	1	affinity chromatography technology	Greenblatt MB (2016)	1
TRIM25	5	SMAD4	9	affinity chromatography technology	Choudhury NR (2017)	1
BIRC3	1	UBC	7	pull down, pull down, enzymatic study	Gyrd-Hansen M (2008), Nakatani Y (2012), Sakamoto H (2015)	3
YAP1	0	NPM1	0	affinity chromatography technology	Enzo E (2015)	1
USP7	14	MCM4	3	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lecona E (2016)	2
TRAF6	0	ID1	0	affinity chromatography technology	Li X (2017)	1
KRT31	0	KRT81	1	two hybrid	Rolland T (2014)	1
HNRNPL	3	BMPR1B	3	affinity chromatography technology	Fei T (2017)	1
TRIM25	5	ADSL	5	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	LMNA	2	affinity chromatography technology	Choudhury NR (2017)	1
CAND1	2	MCM2	3	affinity chromatography technology	Bennett EJ (2010)	1
SMAD2	5	PSMD11	0	two hybrid	Colland F (2004)	1
USP15	4	WAPL	1	biochemical	Havugimana PC (2012)	1
PLK1	0	RNF126	2	two hybrid	Vinayagam A (2011)	1
GTF3C4	0	SPAG9	5	affinity chromatography technology	Boldt K (2016)	1
BTRC	1	CAND1	2	affinity chromatography technology	Coyaud E (2015)	1
PHF7	5	USP7	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SMAD7	1	COPS5	0	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology	Kim BC (2004), Kim BC (2004), Kim BC (2004), Kim BC (2004)	4
PPP4R2	0	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
SART3	2	PPIH	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Boldt K (2016)	2
CUL4B	8	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
TRIM63	0	UCHL1	1	enzymatic study	Loch CM (2012)	1
SMAD1	0	SMURF2	3	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Lin X (2000), Lin X (2000), Komuro A (2004), Zhang Y (2001), Zhang Y (2001), Li L (2004), Chong PA (2010), Colland F (2004), Huttlin EL (2017), Zhou F (2017)	10
USP15	4	TUT1	3	affinity chromatography technology	Sowa ME (2009)	1
HUWE1	22	USP15	4	affinity chromatography technology	Thompson JW (2014)	1
RNF20	9	HIST2H2BE	1	enzymatic study, enzymatic study, enzymatic study	Kim J (2011), Zhu B (2005), Wu L (2014)	3
USP15	4	KRT81	1	affinity chromatography technology	Sowa ME (2009)	1
COPS5	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), He F (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
SOX2	4	USP15	4	affinity chromatography technology	Cox JL (2013)	1
CAND1	2	HIST2H2BE	1	affinity chromatography technology	Bennett EJ (2010)	1
USP15	4	FABP4	3	affinity chromatography technology	Sowa ME (2009)	1
SEM1	0	USP7	14	affinity chromatography technology	Besche HC (2014)	1
USP21	2	USP14	1	enzymatic study	Loch CM (2012)	1
LMNA	2	SMAD1	0	two hybrid	Dittmer TA (2014)	1
PSMB9	0	PSMD11	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRPF4	3	LSM8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017), Boldt K (2016)	3
SEM1	0	HUWE1	22	affinity chromatography technology	Besche HC (2014)	1
USP15	4	TRIM17	5	two hybrid	Hayes SD (2012)	1
MCM2	3	HNRNPL	3	affinity chromatography technology	Drissi R (2015)	1
USP7	14	UBC	7	enzymatic study, enzymatic study, unspecified method, enzymatic study, pull down	Bremm A (2010), Faesen AC (2011), Ernst A (2013), Holowaty MN (2003), Kwasna D (2018)	5
SMAD7	1	ACVR1	4	affinity chromatography technology	Kamiya Y (2010)	1
OTUB1	0	UBE2S	2	enzymatic study	Bremm A (2010)	1
MCM6	5	USP15	4	affinity chromatography technology	Boldt K (2016)	1
CUL3	17	HNRNPL	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
POU5F1	0	HUWE1	22	affinity chromatography technology	Oliviero G (2015)	1
UBE2S	2	ANAPC1	1	pull down	Brown NG (2014)	1
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
UCHL3	1	UBC	7	enzymatic study, enzymatic study, enzymatic study, x-ray crystallography, pull down, x-ray crystallography, pull down, enzymatic study, pull down, pull down, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, pull down, pull down	Bremm A (2010), Boudreaux D (2012), Misaghi S (2005), Misaghi S (2005), Wilkinson KD (1999), Wilkinson KD (1999), Phillips AH (2013), Larsen CN (1998), Wada H (1998), Hemelaar J (2004), Altun M (2015), Flierman D (2016), Zhang X (2017), Kwasna D (2018), Lee YC (2017), Lee YC (2017), Hanpude P (2017)	17
HUWE1	22	MCM4	3	affinity chromatography technology	Thompson JW (2014)	1
SMURF1	4	PRPF31	0	affinity chromatography technology	Xie Y (2013)	1
NOTCH1	25	USP11	3	affinity chromatography technology	Yatim A (2012)	1
SMAD6	9	SMURF2	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Komuro A (2004), Colland F (2004), Herhaus L (2014)	3
USP15	4	FHL1	1	affinity chromatography technology, pull down	Isumi Y (2011), Isumi Y (2011)	2
CDK11A	1	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
TGFBR1	2	TRAF4	1	affinity chromatography technology, affinity chromatography technology	Zhang L (2013), Zhang L (2013)	2
NOTCH1	25	SMC3	16	affinity chromatography technology	Yatim A (2012)	1
HNRNPL	3	CCDC57	8	affinity chromatography technology	Fei T (2017)	1
MEPCE	1	CAND1	2	affinity chromatography technology, affinity chromatography technology	Jeronimo C (2007), Bennett EJ (2010)	2
CDH1	4	LMNA	2	affinity chromatography technology	Catimel B (2005)	1
NOTCH1	25	ANAPC1	1	affinity chromatography technology	Yatim A (2012)	1
EGLN3	0	TCEAL4	0	affinity chromatography technology	Rodriguez J (2016)	1
SENP3	1	MCM4	3	affinity chromatography technology	Wang M (2016)	1
GRK5	7	PSMD11	0	affinity chromatography technology	Wu Z (2012)	1
TRIM25	5	BAG6	2	affinity chromatography technology	Choudhury NR (2017)	1
USP15	4	BAP1	4	enzymatic study	Loch CM (2012)	1
EGLN3	0	WAPL	1	affinity chromatography technology	Rodriguez J (2016)	1
CYLD	2	HNRNPL	3	affinity chromatography technology	Elliott PR (2016)	1
STN1	0	USP4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FN1	17	CAND1	2	affinity chromatography technology	Humphries JD (2009)	1
CDK11A	1	MCM2	3	affinity chromatography technology	Boldt K (2016)	1
SPAG9	5	SMC1A	15	affinity chromatography technology	Boldt K (2016)	1
OTUB1	0	SMAD2	5	affinity chromatography technology, affinity chromatography technology, pull down	Herhaus L (2013), Herhaus L (2013), Herhaus L (2013)	3
EEF2KMT	0	USP15	4	affinity chromatography technology	Huttlin EL (2015)	1
CUL4B	8	ALDOA	0	affinity chromatography technology	Bennett EJ (2010)	1
UBE2E3	0	USP7	14	affinity chromatography technology	Huttlin EL (2017)	1
NPM1	0	USP10	2	affinity chromatography technology	Hein MY (2015)	1
SENP8	0	SMURF1	4	enzymatic study	Xie P (2014)	1
EPS15L1	1	USP15	4	affinity chromatography technology	Boldt K (2016)	1
EGLN3	0	PSMD7	1	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	HUWE1	22	affinity chromatography technology	Bennett EJ (2010)	1
TRIM54	1	UCHL3	1	enzymatic study	Loch CM (2012)	1
COPS7A	0	USP15	4	affinity chromatography technology	Huang X (2016)	1
USP28	3	SENP8	0	enzymatic study	Loch CM (2012)	1
PPP4R2	0	PPP4R3A	3	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Gingras AC (2005), Gingras AC (2005), Gingras AC (2005), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Yadav L (2017), Yadav L (2017)	10
USP4	3	ADSL	5	affinity chromatography technology	Sowa ME (2009)	1
HNRNPL	3	BCR	3	affinity chromatography technology	Fei T (2017)	1
SMAD4	9	SMURF1	4	affinity chromatography technology, affinity chromatography technology	Moren A (2005), Zhang L (2013)	2
UBE2S	2	USP10	2	biochemical	Havugimana PC (2012)	1
USP15	4	SPDL1	2	two hybrid	Rolland T (2014)	1
UBE2E2	1	USP15	4	affinity chromatography technology	Huttlin EL (2017)	1
SMAD7	1	USP11	3	affinity chromatography technology, biochemical, affinity chromatography technology	Al-Salihi MA (2012), Al-Salihi MA (2012), Herhaus L (2014)	3
IVNS1ABP	0	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	CAND1	2	affinity chromatography technology	Emdal KB (2015)	1
PSMD7	1	RNF20	9	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EGLN3	0	DFFA	0	affinity chromatography technology	Rodriguez J (2016)	1
USP33	1	UBC	7	enzymatic study, pull down	Shenoy SK (2014), Kwasna D (2018)	2
MCM2	3	USP15	4	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	ANAPC1	1	affinity chromatography technology	Emdal KB (2015)	1
EPS15L1	1	MCM6	5	affinity chromatography technology	Boldt K (2016)	1
SGTB	2	USP15	4	affinity chromatography technology	Hein MY (2015)	1
SMAD7	1	YAP1	0	two hybrid, genetic interference, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down	Ferrigno O (2002), Ferrigno O (2002), Ferrigno O (2002), Aragon E (2012), Aragon E (2012), Aragon E (2012), Schuchardt BJ (2014)	7
NTRK1	1	USP8	7	affinity chromatography technology	Emdal KB (2015)	1
MDM2	2	NOTCH1	25	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Lim SO (2011), Lim SO (2011), Pettersson S (2012), Pettersson S (2012), Pettersson S (2012)	5
ID1	0	USP15	4	affinity chromatography technology	Hein MY (2015)	1
GTF3C4	0	ANK3	16	affinity chromatography technology	Boldt K (2016)	1
SMURF1	4	TRAF4	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference, enzymatic study	Li S (2010), Li S (2010), Li S (2010), Li S (2010), Li S (2010), Zhang L (2013)	6
CYLD	2	IVNS1ABP	0	affinity chromatography technology	Elliott PR (2016)	1
PRPF31	0	TUT1	3	affinity chromatography technology	Huttlin EL (2017)	1
PRPF4	3	LSM4	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2017), Boldt K (2016)	3
NTRK1	1	USP14	1	affinity chromatography technology	Emdal KB (2015)	1
CYLD	2	PLK1	0	affinity chromatography technology, affinity chromatography technology	Stegmeier F (2007), Stegmeier F (2007)	2
KEAP1	0	CDH1	4	affinity chromatography technology, affinity chromatography technology, pull down, bioid	Kim WD (2012), Kim WD (2012), Kim WD (2012), Guo Z (2014)	4
NPM1	0	MEPCE	1	affinity chromatography technology	Hein MY (2015)	1
COPS5	0	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
SMAD2	5	ANK3	16	two hybrid	Colland F (2004)	1
BTRC	1	WEE1	2	affinity chromatography technology, enzymatic study, pull down, bioid	Watanabe N (2004), Watanabe N (2004), Watanabe N (2004), Coyaud E (2015)	4
CUL3	17	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Chua YS (2011), Chua YS (2011), Tron AE (2012), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Schumacher FR (2015), Schumacher FR (2015), Lo SC (2006), Lo SC (2006)	12
SMAD1	0	UBC	7	two hybrid	Guo X (2001)	1
USP20	3	PSMD7	1	affinity chromatography technology	Sowa ME (2009)	1
TRIM25	5	SPAG9	5	affinity chromatography technology	Choudhury NR (2017)	1
BIRC2	1	OTUB1	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Goncharov T (2013), Goncharov T (2013), Goncharov T (2013)	3
EPS15L1	1	SMC3	16	affinity chromatography technology	Boldt K (2016)	1
UBC	7	PGAM2	1	affinity chromatography technology	Mikawa T (2014)	1
SMURF2	3	AXIN1	1	enzymatic study, affinity chromatography technology	Kim S (2010), Kim S (2010)	2
COPS5	0	LGALS7	0	affinity chromatography technology	Bennett EJ (2010)	1
TRIM17	5	UBC	7	enzymatic study	Woodsmith J (2012)	1
OTUB1	0	BAG6	2	affinity chromatography technology	Scholz CC (2016)	1
SART3	2	PRPF4	3	fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stanek D (2004), Sowa ME (2009), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	5
POU5F1	0	USP15	4	affinity chromatography technology	Oliviero G (2015)	1
CUL3	17	HIST2H2BE	1	affinity chromatography technology	Bennett EJ (2010)	1
EPS15L1	1	SPAG9	5	affinity chromatography technology	Boldt K (2016)	1
NTRK1	1	GTF3C2	2	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	USP20	3	pull down	Kwasna D (2018)	1
POU5F1	0	BAG6	2	affinity chromatography technology	Oliviero G (2015)	1
USP15	4	RNF144B	0	two hybrid	Hayes SD (2012)	1
SMAD7	1	AXIN1	1	affinity chromatography technology	Tang Y (2008)	1
TRAF6	0	MCM7	5	affinity chromatography technology	Ewing RM (2007)	1
STN1	0	MED4	2	affinity chromatography technology	Malovannaya A (2010)	1
CYLD	2	TRIM21	0	affinity chromatography technology	Elliott PR (2016)	1
CDH1	4	ALDOA	0	bioid	Guo Z (2014)	1
FN1	17	ALDOA	0	affinity chromatography technology	Humphries JD (2009)	1
TRIM25	5	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Pauli EK (2014), Pauli EK (2014), Pauli EK (2014), Pauli EK (2014)	4
SMAD2	5	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid, fluorescent resonance energy transfe	Brown KA (2008), Wu RY (1997), Wu RY (1997), Ivanov AA (2017)	4
PTCH1	8	PSMD11	0	affinity chromatography technology	Yamaki Y (2016)	1
MCM2	3	LMNA	2	affinity chromatography technology	Drissi R (2015)	1
UBC	7	EPS15L1	1	pull down	Zhang X (2017)	1
COPS5	0	SMAD4	9	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Wan M (2002), Wan M (2002), Wan M (2002), Wan M (2002), Kim BC (2004), Huang J (2007), Sangadala S (2013), Lee CC (2016), Lee CC (2016)	9
USP21	2	UBC	7	enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, unspecified method, enzymatic study, enzymatic study, pull down, enzymatic study	Bremm A (2010), Faesen AC (2011), Ye Y (2011), Urbe S (2012), Loch CM (2012), Ernst A (2013), Ye Y (2011), Wauer T (2015), Leung I (2016), Michel MA (2017)	10
USP8	7	STAM	3	pull down, affinity chromatography technology, protein complementation assay, affinity chromatography technology	Kato M (2000), Berlin I (2010), Berlin I (2010), Row PE (2006)	4
USP20	3	PLA2G2A	1	enzymatic study	Altun M (2011)	1
WWP2	7	USP15	4	affinity chromatography technology	Chaudhary N (2014)	1
MCM2	3	CTNNB1	30	affinity chromatography technology	Drissi R (2015)	1
CUL3	17	SMC1A	15	affinity chromatography technology	Bennett EJ (2010)	1
EPS15L1	1	SBNO1	4	affinity chromatography technology	Boldt K (2016)	1
UBE2E3	0	CUL3	17	pull down	Plafker KS (2009)	1
PLK1	0	BAG6	2	two hybrid	Vinayagam A (2011)	1
CDH1	4	GAPVD1	6	bioid	Guo Z (2014)	1
USP7	14	PLA2G2A	1	enzymatic study	Altun M (2011)	1
BAG6	2	RNF126	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, pull down	Rolland T (2014), Huttlin EL (2015), Hein MY (2015), OConnor HF (2015), Rodrigo-Brenni MC (2014), Rodrigo-Brenni MC (2014), Rodrigo-Brenni MC (2014), Huttlin EL (2017), Krysztofinska EM (2016), Krysztofinska EM (2016), Krysztofinska EM (2016)	11
SMAD4	9	PSMD11	0	two hybrid	Colland F (2004)	1
POU5F1	0	SOX2	4	pull down, affinity chromatography technology, affinity chromatography technology	Remenyi A (2003), Xu C (2013), Oliviero G (2015)	3
TCEAL4	0	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Hein MY (2015), Hein MY (2015)	5
RNF40	11	HIST2H2BE	1	enzymatic study, enzymatic study	Zhu B (2005), Wu L (2014)	2
PRPF4	3	PRPF31	0	affinity chromatography technology, two hybrid, two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Liu S (2006), Liu S (2006), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	6
TERF2	2	RNF40	11	affinity chromatography technology	Giannone RJ (2010)	1