PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MAD2L1	0	APP	1	pull down	Olah J (2011)	1
SASS6	1	SQSTM1	0	bioid	Gupta GD (2015)	1
CDK13	18	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HSP90AA1	7	TERF1	1	affinity chromatography technology	Hein MY (2015)	1
POLR2F	1	POLR3E	1	affinity chromatography technology	Hein MY (2015)	1
CUL2	3	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
BCL2	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu C (2011), Xu C (2011), Trisciuoglio D (2010)	3
EGFR	5	BPTF	8	affinity chromatography technology	Yao Z (2017)	1
NPM1	0	KEAP1	0	affinity chromatography technology	Chen R (2013)	1
NAF1	0	KPNA6	1	affinity chromatography technology	Hein MY (2015)	1
FERMT3	4	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
FERMT3	4	ZC3H18	4	affinity chromatography technology	Hein MY (2015)	1
RBM45	1	SQSTM1	0	affinity chromatography technology	Bakkar N (2015)	1
XPO1	8	NIPSNAP2	1	affinity chromatography technology	Kirli K (2015)	1
DDIT3	1	MCMBP	3	two hybrid	Rual JF (2005)	1
HSP90AA1	7	PRKCE	6	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Budas GR (2010)	2
ZRANB1	3	UBC	7	affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, x-ray crystallography, enzymatic study, pull down, enzymatic study, pull down, x-ray crystallography, pull down, enzymatic study, pull down, pull down, x-ray crystallography, pull down	Tran H (2008), Tran H (2008), Tran H (2008), Bremm A (2010), Komander D (2009), Licchesi JD (2012), Licchesi JD (2012), Mevissen TE (2013), Komander D (2009), Wauer T (2015), Kristariyanto YA (2015), Kristariyanto YA (2015), Kristariyanto YA (2015), Michel MA (2015), Michel MA (2015), Michel MA (2015), Michel MA (2015), Zhang X (2017)	18
HSP90AB1	2	EEF2	11	affinity chromatography technology	Falsone SF (2005)	1
SQSTM1	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanji K (2012), Chen K (2016), Chen K (2016)	3
MCM2	3	COPG1	5	affinity chromatography technology	Drissi R (2015)	1
CEP135	2	WDR83	1	bioid	Gupta GD (2015)	1
BRCA1	7	COPG1	5	affinity chromatography technology	Ertych N (2016)	1
TERF1	1	BTRC	1	affinity chromatography technology, affinity chromatography technology	Wang C (2013), Wang C (2013)	2
KEAP1	0	LAMA1	15	affinity chromatography technology	Lu K (2017)	1
KEAP1	0	KEAP1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	McMahon M (2006), Wong DP (2010), Wong DP (2010), Zipper LM (2002), Hast BE (2014), Hast BE (2014), Zhang DD (2005), Su C (2015), Chew EH (2007), Ivanov AA (2017)	10
USP11	3	KEAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009)	3
USP11	3	UBC	7	enzymatic study, pull down, pull down	Faesen AC (2011), Zhang X (2017), Kwasna D (2018)	3
DPP3	4	APP	1	pull down	Olah J (2011)	1
KEAP1	0	RAD51	3	affinity chromatography technology	Ma J (2012)	1
CUL3	17	EEF2	11	affinity chromatography technology	Bennett EJ (2010)	1
KEAP1	0	PIDD1	5	two hybrid	Wang J (2011)	1
RBX1	2	CUL2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Dias DC (2002), Ohta T (1999), Ohta T (1999), Maine GN (2007), Hu J (2004), Furukawa M (2002), Mao X (2011), Sufan RI (2006), Sufan RI (2006), Sufan RI (2006), Brower CS (2002), Tron AE (2012), Kamura T (2004), Kristensen AR (2012), Costessi A (2011), Huang DT (2009), Kamura T (1999), Kamura T (1999), Xu J (2015), Cardote TAF (2017)	20
TUBG1	2	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
EGLN3	0	EEF2	11	affinity chromatography technology	Rodriguez J (2016)	1
KEAP1	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang DD (2005), Ichikawa T (2009), Lau A (2010), Li Y (2012), Niture SK (2013), Kaspar JW (2012), Kaspar JW (2012), Zhang DD (2004), Lo SC (2006)	9
AMER1	0	BTRC	1	pull down, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Major MB (2007), Kim TY (2014), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017)	5
KEAP1	0	PSMD10	1	affinity chromatography technology, affinity chromatography technology	Yang C (2016), Yang C (2016)	2
TRIM15	0	FERMT3	4	protein complementation assay	Lee OH (2015)	1
SESN2	3	RBX1	2	affinity chromatography technology	Bae SH (2013)	1
RAF1	3	BCL2	0	pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang HG (1996), Wang HG (1996), Wang HG (1996), Jin S (2005), Jin S (2005), Mazzocca A (2003)	6
SQSTM1	0	KLHL3	1	affinity chromatography technology, affinity chromatography technology	Mori Y (2015), Mori Y (2015)	2
CCNB1	3	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
PAQR3	2	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Zhang Y (2016), Zhang Y (2016)	2
NPM1	0	SQSTM1	0	affinity chromatography technology	Chen R (2013)	1
EEF2	11	PFAS	3	biochemical	Kristensen AR (2012)	1
TERF1	1	MCM2	3	two hybrid	Lee OH (2011)	1
EGLN3	0	NIPSNAP2	1	affinity chromatography technology	Rodriguez J (2016)	1
CUL3	17	RBM45	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bakkar N (2015)	2
CUL3	17	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
EGLN3	0	VWA8	5	affinity chromatography technology	Rodriguez J (2016)	1
GABARAPL2	0	CUL3	17	affinity chromatography technology, pull down	Behrends C (2010), Genau HM (2015)	2
USP11	3	PGAM5	4	affinity chromatography technology	Sowa ME (2009)	1
CDH1	4	SSH3	3	bioid	Guo Z (2014)	1
MLST8	1	SQSTM1	0	affinity chromatography technology	Duran A (2011)	1
EGFR	5	NPM1	0	affinity chromatography technology	Liccardi G (2014)	1
PRKCE	6	IKBKB	1	affinity chromatography technology, enzymatic study	Yang W (2012), Yang W (2012)	2
EGLN3	0	BRCA2	6	affinity chromatography technology	Rodriguez J (2016)	1
KEAP1	0	OXR1	3	two hybrid	Rolland T (2014)	1
BTRC	1	PAQR3	2	affinity chromatography technology, affinity chromatography technology, pull down	Guo W (2016), Guo W (2016), Guo W (2016)	3
BRCA1	7	BPTF	8	affinity chromatography technology	Ertych N (2016)	1
OSBPL10	1	ZC3H18	4	affinity chromatography technology	Sowa ME (2009)	1
HSP90AA1	7	TRIM37	7	affinity chromatography technology	Taipale M (2012)	1
UBC	7	IKBKB	1	pull down	Zhang X (2017)	1
MED4	2	SQSTM1	0	bioid	Lambert JP (2015)	1
MAP1LC3A	0	PDCD6IP	3	affinity chromatography technology	Behrends C (2010)	1
SQSTM1	0	NIPSNAP2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Milan E (2015)	2
GABARAPL1	0	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
TERF1	1	PTMA	2	two hybrid	Lee OH (2011)	1
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
UBE2A	0	KEAP1	0	affinity chromatography technology	An H (2017)	1
KEAP1	0	COPG1	5	affinity chromatography technology	Sowa ME (2009)	1
PGAM5	4	CUL3	17	affinity chromatography technology, affinity chromatography technology	Lo SC (2006), Bennett EJ (2010)	2
GABARAP	0	NIPSNAP2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Dunlop EA (2014)	2
MCM3	2	MCM2	3	two hybrid, two hybrid, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Ramachandran N (2004), Wan C (2015), Drissi R (2015), Huttlin EL (2017), Lossaint G (2013), Mulvaney KM (2016)	8
CTTN	1	KEAP1	0	affinity chromatography technology, affinity chromatography technology, pull down	Ito A (2015), Ito A (2015), Ito A (2015)	3
FBXW11	2	ZC3H18	4	bioid	Coyaud E (2015)	1
USP15	4	NFE2L1	4	affinity chromatography technology	Fukagai K (2016)	1
PRKAG1	1	MCM2	3	affinity chromatography technology	Behrends C (2010)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
GABARAPL2	0	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
CDH1	4	USP15	4	bioid	Guo Z (2014)	1
KEAP1	0	GABPA	0	affinity chromatography technology, affinity chromatography technology	Chew EH (2007), Wang XJ (2009)	2
MAD2L1	0	TSC22D4	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	4
DDIT3	1	CUL3	17	affinity chromatography technology, biochemical	Huang X (2012), Huang X (2012)	2
MCM2	3	NPM1	0	affinity chromatography technology	Drissi R (2015)	1
TERF1	1	DPP3	4	two hybrid	Lee OH (2011)	1
HSP90AA1	7	EEF2	11	affinity chromatography technology	Falsone SF (2005)	1
POLR2F	1	APP	1	pull down	Olah J (2011)	1
IRF1	0	KEAP1	0	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
BRCA1	7	RELA	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Benezra M (2003), Benezra M (2003), Benezra M (2003), Volcic M (2012)	4
CDK13	18	EEF2	11	affinity chromatography technology	So J (2015)	1
EGLN3	0	MLST8	1	affinity chromatography technology	Rodriguez J (2016)	1
KEAP1	0	BBS1	2	affinity chromatography technology	Sowa ME (2009)	1
IKBKB	1	KEAP1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee DF (2009), Lee DF (2009), Lee DF (2009), Lee DF (2009), Lee DF (2009), Kim JE (2010), Kim JE (2010), Niture SK (2013), Hast BE (2014), Hast BE (2014), Edwards MR (2015), Mei ZZ (2016)	12
KEAP1	0	BRCA2	6	affinity chromatography technology, affinity chromatography technology	Ma J (2012), Lu K (2017)	2
TSC22D4	1	FBXW11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	MCM3	2	affinity chromatography technology	Ertych N (2016)	1
MCM2	3	NEU2	0	affinity chromatography technology	Drissi R (2015)	1
GABARAPL1	0	GABARAP	0	affinity chromatography technology	Behrends C (2010)	1
EGLN3	0	KEAP1	0	affinity chromatography technology	Rodriguez J (2016)	1
KEAP1	0	IPO11	0	pull down	Sun Z (2011)	1
CUL3	17	CTTN	1	affinity chromatography technology	Bennett EJ (2010)	1
IRF1	0	HSP90AA1	7	affinity chromatography technology	Gao B (2013)	1
XPO1	8	NPM1	0	unspecified method	Xu D (2012)	1
BTRC	1	NFE2L1	4	affinity chromatography technology, bioid	Coyaud E (2015), Coyaud E (2015)	2
KEAP1	0	XPO1	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kaspar JW (2012), Kaspar JW (2012), Kirli K (2015)	3
CDH1	4	HSP90AB1	2	bioid	Guo Z (2014)	1
CDH5	2	KEAP1	0	affinity chromatography technology	Huttlin EL (2017)	1
XPO1	8	MLST8	1	affinity chromatography technology	Kirli K (2015)	1
RECK	6	KEAP1	0	two hybrid	Rolland T (2014)	1
CDH1	4	BAG3	4	bioid	Guo Z (2014)	1
RAD51	3	HSP90AA1	7	two hybrid	Arroyo R (2015)	1
NFE2L2	1	PGAM5	4	affinity chromatography technology	Lo SC (2008)	1
KEAP1	0	FAM129B	4	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lu K (2017)	2
SQSTM1	0	UBC	7	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, affinity chromatography technology, unspecified method, pull down, pull down, pull down, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, imaging technique, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Vinayagam A (2011), Vadlamudi RK (1996), Tanji K (2012), Matsumoto G (2011), Long J (2008), Long J (2008), Najat D (2009), Najat D (2009), Hocking LJ (2004), Boh BK (2011), Long J (2010), Seibenhener ML (2004), Seibenhener ML (2004), Seibenhener ML (2004), Fenner BJ (2009), Nathan JA (2013), Ciani B (2003), Shi J (2013), Goode A (2014), Bish RA (2007), Lu K (2014), Zhou L (2014), Zhou L (2014), Vadlamudi RK (1996), Long J (2008), Cavey JR (2006), Cavey JR (2006), Kirkin V (2009), Nakayasu ES (2013), Nakayasu ES (2013), Lim J (2015), Milan E (2015), Milan E (2015), Ordureau A (2015), Wurzer B (2015), Zhang X (2017), Wang L (2017), Liu X (2017), Peng H (2017), Donohue E (2014), Nibe Y (2017), Nibe Y (2017), Govindaraju VK (2017)	43
XPO1	8	ATG5	0	affinity chromatography technology	Kirli K (2015)	1
KEAP1	0	CCNB1IP1	0	two hybrid	Rolland T (2014)	1
RAF1	3	PRKCE	6	affinity chromatography technology	Bourbon NA (2001)	1
ATG5	0	KEAP1	0	two hybrid	Rolland T (2014)	1
FBXW11	2	KEAP1	0	affinity chromatography technology	Kim TY (2014)	1
HSP90AA1	7	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
POLR3E	1	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
RELA	1	PSMD10	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Higashitsuji H (2007), Higashitsuji H (2007), Higashitsuji H (2007), Higashitsuji H (2007), Chen Y (2007)	5
KEAP1	0	MCMBP	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Taipale M (2014), Taipale M (2014), Mulvaney KM (2016)	4
XPO1	8	TRIM37	7	affinity chromatography technology	Kirli K (2015)	1
MAP1LC3B	1	SQSTM1	0	two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stelzl U (2005), Behrends C (2010), Vinayagam A (2011), Kirkin V (2009), Kirkin V (2009), Liang X (2013), Liang X (2013), Novak I (2010), Novak I (2010), Rogov VV (2012), Gao W (2013), Maruyama Y (2014), Maruyama Y (2014), Maruyama Y (2014), Yamashita SI (2014), Wurzer B (2015), Wurzer B (2015), Wurzer B (2015), Sun A (2017), Cohen-Kaplan V (2016), Dou Z (2015), Galindo-Moreno M (2017)	22
RELA	1	UBC	7	affinity chromatography technology	Schweitzer K (2015)	1
EGLN3	0	GPRASP2	0	affinity chromatography technology	Rodriguez J (2016)	1
NPM1	0	RELA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid	Wang J (2011), Xu Y (2008), Xu Y (2008), Xu Y (2008)	4
UBC	7	NPM1	0	affinity chromatography technology, pull down	Matsumoto M (2005), Koike A (2010)	2
BRCA1	7	XPO1	8	affinity chromatography technology	Ertych N (2016)	1
EGFR	5	CLU	1	affinity chromatography technology	Tong J (2014)	1
EGLN3	0	TRIM37	7	affinity chromatography technology	Rodriguez J (2016)	1
EGLN3	0	COPG1	5	affinity chromatography technology	Rodriguez J (2016)	1
XPO1	8	ARCN1	1	affinity chromatography technology	Kirli K (2015)	1
KEAP1	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, two hybrid	Niture SK (2013), Prince TL (2015), Prince TL (2015)	3
PRKAG1	1	KEAP1	0	two hybrid	Rolland T (2014)	1
MAP1LC3B	1	ATG5	0	affinity chromatography technology	Behrends C (2010)	1
BAG3	4	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gamerdinger M (2009), Gamerdinger M (2009), Chen Y (2013)	3
CEP135	2	SQSTM1	0	bioid	Gupta GD (2015)	1
XPO1	8	CLU	1	affinity chromatography technology	Leskov KS (2011)	1
MCM3	2	HSP90AA1	7	biochemical	Kristensen AR (2012)	1
UBC	7	ARCN1	1	affinity chromatography technology	Matsumoto M (2005)	1
MAP1LC3A	0	TMEM160	0	affinity chromatography technology	Behrends C (2010)	1
RELA	1	PPP1R13L	3	two hybrid, pull down, pull down, affinity chromatography technology	Yang JP (1999), Takada N (2002), Yang JP (1999), Yang JP (1999)	4
PALB2	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang F (2009), Sy SM (2009), Zhang F (2009), Zhang F (2009), Zhang F (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Johnson N (2013), Anantha RW (2013), Hill SJ (2014), Bleuyard JY (2012), Orthwein A (2015), Orthwein A (2015), Loke J (2015), Simhadri S (2014), Ma J (2012), Ma J (2012), Foo TK (2017)	22
KEAP1	0	CUL2	3	affinity chromatography technology	Zhang DD (2004)	1
CEP135	2	KEAP1	0	bioid	Gupta GD (2015)	1
GPRASP2	0	KEAP1	0	affinity chromatography technology	Li S (2014)	1
CUL3	17	KPNA6	1	affinity chromatography technology	Bennett EJ (2010)	1
MED4	2	KEAP1	0	bioid	Lambert JP (2015)	1
EGFR	5	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay	Citri A (2002), Yang S (2006), Shimamura T (2005), Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014)	8
CEP135	2	TMEM160	0	bioid	Gupta GD (2015)	1
APP	1	TUBG1	2	pull down	Virok DP (2011)	1
COPG1	5	ARCN1	1	pull down, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology	Harter C (1998), Wegmann D (2004), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017)	6
SESN2	3	KEAP1	0	affinity chromatography technology	Bae SH (2013)	1
UBC	7	GET4	3	affinity chromatography technology	Matsumoto M (2005)	1
KEAP1	0	MAPKBP1	8	two hybrid	Rolland T (2014)	1
NPM1	0	COPG1	5	affinity chromatography technology	Chen R (2013)	1
CLU	1	TSC22D4	1	two hybrid	Wang J (2011)	1
NPM1	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Sato K (2004), Ertych N (2016)	2
BRCA1	7	RAD51	3	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Dong Y (2003), Dong Y (2003), Dong Y (2003), Wang Q (2001), Chen J (1998), Mok MT (2010), Scully R (1997), Scully R (1997), Johnson N (2013), Jung YS (2014), Jung YS (2014), Parameswaran B (2015)	13
GABPA	0	APP	1	pull down	Olah J (2011)	1
KEAP1	0	TMEM160	0	affinity chromatography technology	Sowa ME (2009)	1
SSH3	3	RELA	1	bioid	St-Denis N (2016)	1
RBX1	2	APP	1	pull down	Olah J (2011)	1
TERF1	1	KEAP1	0	two hybrid	Lee OH (2011)	1
EGFR	5	RAF1	3	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
CUL2	3	UBC	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Bish RA (2007), Wu K (2016)	3
MAP1LC3B	1	UBC	7	imaging technique	Liu X (2017)	1
CAT	3	APP	1	pull down	Olah J (2011)	1
MAP1LC3B	1	TMEM160	0	affinity chromatography technology	Behrends C (2010)	1
ZC3H18	4	KEAP1	0	affinity chromatography technology	Huttlin EL (2017)	1
CASP1	1	CUL3	17	affinity chromatography technology	Garstkiewicz M (2017)	1
BPTF	8	KEAP1	0	two hybrid, pull down, imaging technique, pull down	Strachan GD (2004), Strachan GD (2004), Strachan GD (2004), Strachan GD (2004)	4
CUL3	17	GPRASP2	0	affinity chromatography technology	Bennett EJ (2010)	1
XPO1	8	RELA	1	affinity chromatography technology	Kirli K (2015)	1
CUL3	17	WDR1	3	affinity chromatography technology	Wimuttisuk W (2014)	1
TRIM15	0	KEAP1	0	protein complementation assay	Lee OH (2015)	1
MAP1LC3B	1	GABARAPL2	0	pull down	Maruyama Y (2014)	1
KEAP1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang XJ (2008), Rachakonda G (2008), Rachakonda G (2008), Nioi P (2007), Chew EH (2007), Chew EH (2007), Zhang DD (2005), Furukawa M (2005), Furukawa M (2005), Furukawa M (2005), Zhang DD (2004), Cullinan SB (2004), Kobayashi A (2004), Kobayashi A (2004), McMahon M (2006), Ichikawa T (2009), Lee DF (2009), Wong DP (2010), Wong DP (2010), Lau A (2010), Lau A (2010), Hur W (2010), Bennett EJ (2010), Yao JW (2012), Li Y (2012), Choo YY (2012), Kansanen E (2011), Kansanen E (2011), Niture SK (2013), Hast BE (2014), Cleasby A (2014), Kaspar JW (2012), Kaspar JW (2012), Su C (2015), Su C (2015), Huo L (2015), Dubiel D (2015), Lo SC (2006), Wu G (2017), Villeneuve NF (2013), Villeneuve NF (2013), Villeneuve NF (2013), Dong T (2016)	43
CCNB1	3	SQSTM1	0	pull down	Linares JF (2011)	1
MYO7A	6	CDH1	4	affinity chromatography technology	Kuessel-Andermann P (2000)	1
WDR83	1	PPP1R13L	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
OSBPL10	1	NIPSNAP2	1	affinity chromatography technology	Sowa ME (2009)	1
ENC1	0	RBX1	2	affinity chromatography technology	Zhang DD (2005)	1
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
EGFR	5	MCM3	2	affinity chromatography technology	Liccardi G (2014)	1
UBE2A	0	PDCD6IP	3	affinity chromatography technology	An H (2017)	1
HSP90AA1	7	BTRC	1	affinity chromatography technology	Taipale M (2012)	1
BTRC	1	KEAP1	0	affinity chromatography technology, bioid	Sowa ME (2009), Coyaud E (2015)	2
KEAP1	0	BRCA1	7	affinity chromatography technology	Ma J (2012)	1
PSMD10	1	SQSTM1	0	biochemical	Kristensen AR (2012)	1
NPM1	0	HSP90AB1	2	affinity chromatography technology	Chen R (2013)	1
CUL3	17	NFE2L2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Furukawa M (2005), Cullinan SB (2004), Cullinan SB (2004)	3
PALB2	3	KEAP1	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Orthwein A (2015), Orthwein A (2015), Simhadri S (2014), Ma J (2012), Ma J (2012), Ma J (2012), Ma J (2012), Lu K (2017)	8
UBC	7	PSMD10	1	affinity chromatography technology, pull down	Matsumoto M (2005), Zhang X (2017)	2
MAP1LC3A	0	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
KEAP1	0	PGAM5	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lo SC (2006), Lo SC (2006), Lo SC (2008), Lo SC (2008), Niture SK (2013), Lu K (2017)	7
FBXW11	2	NFE2L2	1	affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Low TY (2014)	2
EGLN3	0	MAD2L1	0	affinity chromatography technology	Rodriguez J (2016)	1
BPTF	8	NFE2L2	1	pull down	Strachan GD (2004)	1
XPO1	8	GABARAPL1	0	affinity chromatography technology	Kirli K (2015)	1
XPO1	8	IPO11	0	biochemical	Wan C (2015)	1
EGLN3	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
BAD	1	BCL2	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, pull down, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology	Chen L (2005), Yang E (1995), Yang E (1995), Edlich F (2005), Edlich F (2005), Jin S (2005), Zha J (1997), Zha J (1997), Zha J (1997), Certo M (2006), Craik AC (2010), Schuermann A (2000), Schuermann A (2000)	13
MAP1LC3A	0	UBC	7	biochemical, imaging technique	Fujita N (2013), Govindaraju VK (2017)	2
MCM2	3	ARCN1	1	affinity chromatography technology	Drissi R (2015)	1
BAG3	4	PDCD6IP	3	affinity chromatography technology	Chen Y (2013)	1
USP11	3	OSBPL10	1	affinity chromatography technology	Sowa ME (2009)	1
KLHL2	0	KLHL3	1	affinity chromatography technology	Huttlin EL (2017)	1
FBXW11	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Suzuki H (2000), Suzuki H (2000), Sowa ME (2009), Sowa ME (2009), Coyaud E (2015), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017), Liu X (2017)	9
SNRPN	0	WDR83	1	affinity chromatography technology	Huttlin EL (2017)	1
BTRC	1	CCNB1	3	affinity chromatography technology, affinity chromatography technology	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	2
XPO1	8	SQSTM1	0	affinity chromatography technology	Kirli K (2015)	1
NPM1	0	HSP90AA1	7	affinity chromatography technology	Chen R (2013)	1
RBX1	2	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Furukawa M (2005), Hu J (2004), Furukawa M (2002), Ichikawa T (2009), Ichikawa T (2009), Lee DF (2009), Tron AE (2012), Oshikawa K (2003), Plafker KS (2009), Lu A (2013), Meyer-Schaller N (2009), Theurillat JP (2014), Huang DT (2009), Ibeawuchi SR (2015), Schumacher FR (2015), Kasahara K (2014), Kasahara K (2014)	18
MAP1LC3B	1	KEAP1	0	affinity chromatography technology	Behrends C (2010)	1
MYO7A	6	KEAP1	0	two hybrid	Velichkova M (2002)	1
OSBPL10	1	KEAP1	0	affinity chromatography technology	Sowa ME (2009)	1
NEU2	0	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NIPSNAP2	1	PFAS	3	affinity chromatography technology	Behrends C (2010)	1
BRCA1	7	PDCD6IP	3	affinity chromatography technology	Ertych N (2016)	1
MAP1LC3B	1	CUL3	17	pull down	Genau HM (2015)	1
KEAP1	0	RBM45	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bakkar N (2015), Bakkar N (2015)	3
KEAP1	0	TRIM37	7	affinity chromatography technology	Lu K (2017)	1
TUBG1	2	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Hein MY (2015)	2
SESN1	2	RBX1	2	affinity chromatography technology	Bae SH (2013)	1
KEAP1	0	ENC1	0	affinity chromatography technology	Wang XJ (2009)	1
XPO1	8	NAF1	0	affinity chromatography technology	Kirli K (2015)	1
NFE2L2	1	ENC1	0	affinity chromatography technology, pull down, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Seng S (2007), Seng S (2007), Seng S (2009), Seng S (2009), Seng S (2009), Seng S (2010), Seng S (2010)	7
KEAP1	0	UBC	7	affinity chromatography technology, affinity chromatography technology, pull down	Gjyshi O (2015), Su C (2015), Zhang X (2017)	3
BRCA2	6	RAD51	3	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sharan SK (1997), Lin HR (2003), Yu DS (2003), Yu DS (2003), Chen PL (1998), Chen PL (1998), Chen PL (1998), Dong Y (2003), Dong Y (2003), Dong Y (2003), Sarkisian CJ (2001), Wong AK (1997), Wong AK (1997), Katagiri T (1998), Katagiri T (1998), Pellegrini L (2002), Tarsounas M (2004), Liu J (2001), Chen J (1998), Sharan SK (1997), Marmorstein LY (1998), Ohashi A (2005), Shivji MK (2006), Xia B (2006), Xia B (2006), Badie S (2010), Liu J (2010), Carreira A (2011), Chen CF (1999), Chen CF (1999), Chen CF (1999), Lee M (2011), Esashi F (2005), Esashi F (2005), Esashi F (2005), Thorslund T (2007), Thorslund T (2007), Esashi F (2007), Brough R (2012), Zhao W (2015), Chu WK (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Trego KS (2016), Luo K (2016)	46
KEAP1	0	MAZ	2	affinity chromatography technology	Sowa ME (2009)	1
HSP90AB1	2	MCM2	3	biochemical, affinity chromatography technology	Kristensen AR (2012), Drissi R (2015)	2
KEAP1	0	SLK	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Hast BE (2013), Hast BE (2014), Hast BE (2014)	4
EGFR	5	FAM129B	4	affinity chromatography technology, pull down, enzymatic study	Ji H (2016), Ji H (2016), Ji H (2016)	3
CPEB2	7	KEAP1	0	two hybrid	Chen PJ (2012)	1
IKBKB	1	RELA	1	enzymatic study, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology	Buss H (2004), Schwabe RF (2005), Dan HC (2008), Chen TC (2014), Busch F (2012)	5
CDK13	18	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL2	3	MCM3	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Bish RA (2007), Wu K (2016)	4
CDH1	4	CTTN	1	bioid	Guo Z (2014)	1
GABARAP	0	GABARAPL2	0	affinity chromatography technology	Behrends C (2010)	1
FBXW11	2	ZRANB1	3	affinity chromatography technology	Sowa ME (2009)	1
NFE2L2	1	CDH1	4	affinity chromatography technology, affinity chromatography technology, pull down	Kim WD (2012), Kim WD (2012), Kim WD (2012)	3
CUL3	17	NIPSNAP2	1	affinity chromatography technology	Bennett EJ (2010)	1
CDH1	4	FAM129B	4	bioid	Guo Z (2014)	1
BRCA1	7	CCNB1	3	pull down, affinity chromatography technology, enzymatic study	Wang H (1997), Shabbeer S (2013), Shabbeer S (2013)	3
CDH1	4	PPP1R13L	3	bioid	Guo Z (2014)	1
SSH3	3	PFAS	3	bioid	St-Denis N (2016)	1
OSBPL10	1	BBS1	2	affinity chromatography technology	Sowa ME (2009)	1
TERF1	1	CDK13	18	affinity chromatography technology	Giannone RJ (2010)	1
TSC22D4	1	TSC22D2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BBS1	2	DPP3	4	affinity chromatography technology	Huttlin EL (2017)	1
GLRX5	0	APP	1	pull down	Olah J (2011)	1
KEAP1	0	ARCN1	1	affinity chromatography technology	Sowa ME (2009)	1
MED4	2	CEP135	2	bioid, bioid	Lambert JP (2015), Gupta GD (2015)	2
XPO1	8	PPP1R13L	3	affinity chromatography technology	Kirli K (2015)	1
AK4	2	APP	1	pull down	Olah J (2011)	1
FAM46A	2	KEAP1	0	two hybrid	Colland F (2004)	1
CDH1	4	SLK	2	bioid	Guo Z (2014)	1
EGFR	5	CHD6	6	affinity chromatography technology	Yao Z (2017)	1
HSP90AB1	2	KEAP1	0	affinity chromatography technology, two hybrid	Prince TL (2015), Prince TL (2015)	2
CDH1	4	NIPSNAP2	1	affinity chromatography technology	Catimel B (2005)	1
BRCA1	7	CUL2	3	affinity chromatography technology	Ertych N (2016)	1
HSP90AB1	2	IKBKB	1	imaging technique	Chen TC (2014)	1
XPO1	8	AMER1	0	affinity chromatography technology	Kirli K (2015)	1
BRCA1	7	TERF1	1	affinity chromatography technology, affinity chromatography technology	Ballal RD (2009), Ballal RD (2009)	2
KEAP1	0	KLHL3	1	two hybrid	Rolland T (2014)	1
GABARAPL1	0	KEAP1	0	affinity chromatography technology	Behrends C (2010)	1
NEIL2	2	KEAP1	0	affinity chromatography technology	Hur W (2010)	1
SQSTM1	0	BPTF	8	two hybrid	Vinayagam A (2011)	1
KLHL2	0	GPRASP2	0	affinity chromatography technology	Huttlin EL (2017)	1
FERMT3	4	USP15	4	affinity chromatography technology	Hein MY (2015)	1
PRKCE	6	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology	Cheng MB (2010), Cheng MB (2010)	2
TSC22D4	1	BTRC	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA2	6	BRCA1	7	affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarkisian CJ (2001), Reuter TY (2003), Dong Y (2003), Chen J (1998), Chen J (1998), Villarroel MC (2011), Kumaraswamy E (2007), Sy SM (2009), Sy SM (2009), Sy SM (2009), Johnson N (2013), Hill SJ (2014), Loke J (2015)	13
NPM1	0	EEF2	11	affinity chromatography technology	Chen R (2013)	1
EGLN3	0	AMER1	0	affinity chromatography technology	Rodriguez J (2016)	1
NAF1	0	RAD51	3	affinity chromatography technology	Hein MY (2015)	1
PRKCE	6	BAD	1	affinity chromatography technology, affinity chromatography technology	Thimmaiah KN (2010), Thimmaiah KN (2010)	2
CDK20	0	RAF1	3	affinity chromatography technology	Varjosalo M (2013)	1
GABARAP	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Behrends C (2010), Kirkin V (2009), Maruyama Y (2014), Dunlop EA (2014), Wurzer B (2015), Wurzer B (2015)	6
SQSTM1	0	GABARAPL2	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid	Rual JF (2005), Behrends C (2010), Vinayagam A (2011), Shvets E (2011), Kirkin V (2009), Kirkin V (2009), Maruyama Y (2014), Rolland T (2014), Yu H (2011)	9
FBXW11	2	RELA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim TY (2014), Coyaud E (2015), Huttlin EL (2017)	3
BRCA1	7	MCM2	3	affinity chromatography technology	Ertych N (2016)	1
EGLN3	0	CTTN	1	affinity chromatography technology	Rodriguez J (2016)	1
CAT	3	KEAP1	0	two hybrid	Wang J (2011)	1
CDK6	0	MCM2	3	pull down	Ramachandran N (2004)	1
HSP90AA1	7	CDK6	0	affinity chromatography technology	Taipale M (2012)	1
PRKCE	6	KEAP1	0	enzymatic study	Niture SK (2013)	1
SESN1	2	KEAP1	0	affinity chromatography technology	Bae SH (2013)	1
HSP90AA1	7	FBXW11	2	affinity chromatography technology	Taipale M (2012)	1
KEAP1	0	EGFR	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Huo L (2015), Huo L (2015), Huo L (2015)	3
RAF1	3	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NPM1	0	CTTN	1	affinity chromatography technology	Chen R (2013)	1
CTTN	1	BTRC	1	affinity chromatography technology	Zhao J (2012)	1
CUL3	17	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
GAR1	0	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
EGFR	5	PRKCE	6	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
SSH3	3	KEAP1	0	affinity chromatography technology	Li X (2016)	1
KEAP1	0	NUDT4	2	two hybrid	Rolland T (2014)	1
MED4	2	USP15	4	bioid	Lambert JP (2015)	1
MED4	2	SLK	2	bioid	Lambert JP (2015)	1
KLHL3	1	RBX1	2	affinity chromatography technology	Ohta A (2013)	1
BRCA2	6	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Schoenfeld AR (2004), Schoenfeld AR (2004), Schoenfeld AR (2004), Schoenfeld AR (2004)	4
DDIT3	1	KEAP1	0	biochemical	Huang X (2012)	1
BPTF	8	MAZ	2	two hybrid, pull down, pull down, two hybrid	Jordan-Sciutto KL (2000), Jordan-Sciutto KL (2000), Jordan-Sciutto KL (2000), Strachan GD (2004)	4
MAP1LC3A	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, biochemical, imaging technique, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, affinity chromatography technology	Shvets E (2008), Shvets E (2008), Behrends C (2010), Gao Z (2010), Pan JA (2011), Pankiv S (2007), Pankiv S (2007), Shvets E (2011), Tung YT (2010), Bjorkoy G (2005), Kirkin V (2009), Lim J (2011), Lim J (2011), Pan JA (2012), Lee DY (2013), Wang BS (2013), Wang BS (2013), Sansanwal P (2012), Shi J (2013), Fujita N (2013), Chen X (2014), Liu XD (2014), Noda NN (2008), Noda NN (2008), Matsuzawa Y (2015), Matsuzawa Y (2015), Rui YN (2015), Rui YN (2015), Ciuffa R (2015), Wang N (2013), Hua F (2015), Rui YN (2015), Cha-Molstad H (2015), Paul S (2012), Puvirajesinghe TM (2016), Wang L (2017), Cha-Molstad H (2017), Peng H (2017), Lee Y (2017)	39
KEAP1	0	SQSTM1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Jain A (2010), Jain A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Lau A (2010), Inami Y (2011), Fan W (2010), Copple IM (2010), Copple IM (2010), Wright T (2013), Tanji K (2013), Ichimura Y (2013), Ichimura Y (2013), Ichimura Y (2013), Hast BE (2014), Hast BE (2014), Lerner C (2013), Rolland T (2014), Gjyshi O (2015), Bakkar N (2015), Milan E (2015), Park S (2016), Ge W (2017), Mildenberger J (2017), Lu K (2017), Lee Y (2017)	30
MAP1LC3A	0	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Fan W (2010)	2
BRCA1	7	CDH1	4	genetic interference	Shen JP (2017)	1
EGLN3	0	PFAS	3	affinity chromatography technology	Rodriguez J (2016)	1
EGFR	5	GABARAPL2	0	protein complementation assay	Deribe YL (2009)	1
RBX1	2	BTRC	1	affinity chromatography technology, affinity chromatography technology, bioid	Tan M (2010), Oshikawa K (2003), Coyaud E (2015)	3
KEAP1	0	GET4	3	affinity chromatography technology	Sowa ME (2009)	1
PALB2	3	CUL3	17	affinity chromatography technology	Orthwein A (2015)	1
ZC3H18	4	WDR83	1	affinity chromatography technology	Huttlin EL (2017)	1
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
XPO1	8	TUBG1	2	affinity chromatography technology	Kirli K (2015)	1
KEAP1	0	LSM3	2	two hybrid	Rolland T (2014)	1
TERF1	1	HSP90AB1	2	two hybrid	Lee OH (2011)	1
NPM1	0	APP	1	pull down	Olah J (2011)	1
EGLN3	0	BRCA1	7	affinity chromatography technology	Rodriguez J (2016)	1
PALB2	3	BRCA2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Hayakawa T (2010), Zhang F (2009), Sy SM (2009), Zhang F (2009), Xia B (2007), Xia B (2006), Xia B (2006), Xia B (2006), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Oliver AW (2009), Oliver AW (2009), Oliver AW (2009), Anantha RW (2013), Bleuyard JY (2012), Brough R (2012), Orthwein A (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Simhadri S (2014), Byrd PJ (2016), Park JY (2014), Park JY (2014), Ma J (2012), Ma J (2012), Luijsterburg MS (2017), Luijsterburg MS (2017), Foo TK (2017)	32
CUL3	17	MCMBP	3	affinity chromatography technology	Bennett EJ (2010)	1
PGAM5	4	RBX1	2	affinity chromatography technology	Lo SC (2006)	1
MAP1LC3A	0	APP	1	pull down	Olah J (2011)	1
CASP1	1	NFE2L2	1	affinity chromatography technology	Garstkiewicz M (2017)	1
GLRX5	0	KEAP1	0	two hybrid	Wang J (2011)	1
RAF1	3	WDR83	1	affinity chromatography technology	Vomastek T (2004)	1
GABARAPL1	0	CUL3	17	affinity chromatography technology, pull down	Behrends C (2010), Genau HM (2015)	2
EGFR	5	APP	1	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
EGFR	5	AK4	2	affinity chromatography technology	Tong J (2014)	1
FBXW11	2	RBX1	2	affinity chromatography technology	Tan P (1999)	1
KEAP1	0	PDCD6IP	3	two hybrid	Wang J (2011)	1
MAP1LC3A	0	EGFR	5	affinity chromatography technology	Wang BS (2013)	1
PTMA	2	CCNB1	3	biochemical	Freire J (2001)	1
BRCA1	7	TUBG1	2	imaging technique, affinity chromatography technology, pull down, biochemical, imaging technique, affinity chromatography technology, enzymatic study, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down	Hsu LC (2001), Hsu LC (2001), Hsu LC (2001), Hsu LC (1998), Hsu LC (1998), Hsu LC (1998), Starita LM (2004), Brodie KM (2012), Tarapore P (2012), Tarapore P (2012), Tarapore P (2012), Matsuzawa A (2014)	12
LSM3	2	WDR83	1	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
MCMBP	3	MCM2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014), Drissi R (2015)	3
PPP1R13L	3	NFE2L2	1	affinity chromatography technology	Ge W (2017)	1
SQSTM1	0	CUL3	17	imaging technique, affinity chromatography technology	Lau A (2010), Mori Y (2015)	2
PALB2	3	RAD51	3	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Dray E (2010), Hayakawa T (2010), Zhang F (2009), Zhang F (2009), Xia B (2006), Anantha RW (2013), Bleuyard JY (2012), Trego KS (2016), Trego KS (2016), Trego KS (2016), Simhadri S (2014), Park JY (2014), Park JY (2014), Ma J (2012), Ma J (2012), Luijsterburg MS (2017), Foo TK (2017), Foo TK (2017)	18
SYNE4	1	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KEAP1	0	NIPSNAP2	1	affinity chromatography technology	Sowa ME (2009)	1
XPO1	8	CCNB1	3	affinity chromatography technology	Kirli K (2015)	1
POLR2F	1	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
KEAP1	0	WDR1	3	affinity chromatography technology, affinity chromatography technology	Hast BE (2013), Hast BE (2013)	2
BAG3	4	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
MAP1LC3B	1	GABARAP	0	affinity chromatography technology	Behrends C (2010)	1
EGLN3	0	USP15	4	affinity chromatography technology	Rodriguez J (2016)	1
USP15	4	KEAP1	0	enzymatic study	Villeneuve NF (2013)	1
FBXW11	2	BAG3	4	affinity chromatography technology	Low TY (2014)	1
AMER1	0	FBXW11	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Major MB (2007), Kim TY (2014), Coyaud E (2015), Low TY (2014), Huttlin EL (2017), Camp ND (2012)	6
RELA	1	CUL2	3	affinity chromatography technology, affinity chromatography technology	Geng H (2009), Wang Y (2014)	2
EGFR	5	TUBG1	2	affinity chromatography technology	Tong J (2014)	1
MCM2	3	KEAP1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Mulvaney KM (2016), Mulvaney KM (2016), Mulvaney KM (2016)	3
GABARAP	0	KEAP1	0	affinity chromatography technology	Behrends C (2010)	1
NPM1	0	USP15	4	affinity chromatography technology	Chen R (2013)	1
RELA	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Spencer E (1999), Spencer E (1999), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017)	5
EGFR	5	SESN2	3	affinity chromatography technology	Yao Z (2017)	1
EGFR	5	CTTN	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
MCM2	3	CAT	3	affinity chromatography technology	Drissi R (2015)	1
MCM2	3	UBC	7	affinity chromatography technology	Drissi R (2015)	1
CUL3	17	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
KEAP1	0	DPP3	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hast BE (2013), Hast BE (2014), Hast BE (2014), Rolland T (2014), Yu H (2011), Lu K (2017), Lu K (2017), Lu K (2017)	8
EGFR	5	CDK13	18	affinity chromatography technology	Yao Z (2017)	1
GABARAPL1	0	TMEM160	0	affinity chromatography technology	Behrends C (2010)	1
CDK13	18	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KEAP1	0	NFE2L1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Yu M (2011), Wang W (2006), Wang W (2006), Wang J (2011), Niture SK (2013)	5
MCM2	3	APP	1	pull down	Olah J (2011)	1
NAF1	0	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
CASP1	1	RBX1	2	affinity chromatography technology	Garstkiewicz M (2017)	1
BCL2	0	SQSTM1	0	affinity chromatography technology, pull down	Zhou L (2013), Zhou L (2014)	2
KLHL2	0	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Mai A (2004), Huttlin EL (2017)	2
UBC	7	HSP90AB1	2	affinity chromatography technology	Bish RA (2007)	1
EGFR	5	XPO1	8	affinity chromatography technology	Foerster S (2013)	1
CUL3	17	PDCD6IP	3	affinity chromatography technology	Bennett EJ (2010)	1
PAQR3	2	NFE2L2	1	affinity chromatography technology, affinity chromatography technology	Zhang Y (2016), Zhang Y (2016)	2
ARCN1	1	APP	1	pull down	Olah J (2011)	1
GABARAPL2	0	APP	1	pull down	Olah J (2011)	1
KEAP1	0	PFAS	3	affinity chromatography technology	Sowa ME (2009)	1
KEAP1	0	BCL2	0	affinity chromatography technology	Niture SK (2013)	1
GABARAP	0	CUL3	17	pull down	Genau HM (2015)	1
UBC	7	LAMA1	15	affinity chromatography technology, pull down	Matsumoto M (2005), Zhang X (2017)	2
P3H3	1	KEAP1	0	affinity chromatography technology	Huttlin EL (2017)	1
SESN1	2	SQSTM1	0	affinity chromatography technology	Bae SH (2013)	1
SESN2	3	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Bae SH (2013), Ro SH (2014), Kim MJ (2016), Kim MJ (2016)	4
OSBPL10	1	PGAM5	4	affinity chromatography technology	Sowa ME (2009)	1
USP15	4	BTRC	1	affinity chromatography technology	Greenblatt MB (2016)	1
CDK20	0	EEF2	11	affinity chromatography technology	Varjosalo M (2013)	1
EGLN3	0	ARCN1	1	affinity chromatography technology	Rodriguez J (2016)	1
BRCA1	7	NFE2L2	1	affinity chromatography technology, affinity chromatography technology	Gorrini C (2013), Gorrini C (2013)	2
EGLN3	0	MCM3	2	affinity chromatography technology	Rodriguez J (2016)	1
KEAP1	0	KPNA6	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Sun Z (2011), Sun Z (2011), Sun Z (2011), Sun Z (2011)	4
BCL2	0	IKBKB	1	affinity chromatography technology	Bodur C (2012)	1
USP15	4	UBC	7	pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down	Hetfeld BK (2005), Bremm A (2010), Komander D (2009), Loch CM (2012), Herhaus L (2014), Wauer T (2015), Das T (2017), Zhang X (2017), Kwasna D (2018)	9
RBM45	1	NFE2L2	1	affinity chromatography technology	Bakkar N (2015)	1
USP11	3	PALB2	3	enzymatic study, affinity chromatography technology	Orthwein A (2015), Orthwein A (2015)	2
ETF1	2	KEAP1	0	two hybrid, affinity chromatography technology, two hybrid	Rual JF (2005), Sowa ME (2009), Rolland T (2014)	3
EGLN3	0	SQSTM1	0	affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology	Rantanen K (2013), Rantanen K (2013), Rantanen K (2013), Rodriguez J (2016)	4
BAD	1	KEAP1	0	two hybrid	Wang J (2011)	1
UBC	7	TMEM160	0	pull down	Nathan JA (2013)	1
EGFR	5	CDH5	2	two hybrid, protein complementation assay	Kotlyar M (2015), Petschnigg J (2014)	2
CUL3	17	MAD2L1	0	affinity chromatography technology	Bennett EJ (2010)	1
TUBG1	2	PDCD6IP	3	affinity chromatography technology	Schmidt MH (2003)	1
EGLN3	0	PGAM5	4	affinity chromatography technology	Rodriguez J (2016)	1
AK4	2	KEAP1	0	two hybrid	Vinayagam A (2011)	1
IKBKB	1	HSP90AA1	7	affinity chromatography technology	Xue J (2010)	1
GPRASP2	0	RAF1	3	affinity chromatography technology	Li S (2014)	1
FBXW11	2	NFE2L1	4	affinity chromatography technology	Low TY (2014)	1
KEAP1	0	PPP1R13L	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Ge W (2017), Ge W (2017), Ge W (2017), Ge W (2017)	4
APP	1	KEAP1	0	affinity chromatography technology	Huttlin EL (2017)	1
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
HSP90AB1	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Cheng MB (2010), Gano JJ (2010), Skarra DV (2011), Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Wan C (2015), Hein MY (2015)	8
CUL3	17	MCM3	2	affinity chromatography technology	Bennett EJ (2010)	1
MCM2	3	XPO1	8	affinity chromatography technology	Drissi R (2015)	1
ZRANB1	3	KEAP1	0	affinity chromatography technology	Sowa ME (2009)	1
CUL3	17	NPM1	0	affinity chromatography technology	Bennett EJ (2010)	1
KEAP1	0	NFE2L2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, unspecified method, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cullinan SB (2003), Shibata T (2008), Wang XJ (2008), Nioi P (2007), Tanigawa S (2007), Tanigawa S (2007), Hong F (2005), Furukawa M (2005), Furukawa M (2005), Zhang DD (2003), McMahon M (2006), Ichikawa T (2009), Niture SK (2009), Niture SK (2009), Wu JH (2010), Wong DP (2010), Wong DP (2010), Yu M (2011), Lau A (2010), Lau A (2010), Kay HY (2010), Sun Z (2011), Sun Z (2011), Li X (2004), Li X (2004), Lo SC (2008), Plafker KS (2010), Plafker KS (2010), Yao JW (2012), Li Y (2012), Lo SC (2006), Lo SC (2006), Lo SC (2006), Eggler AL (2005), Zipper LM (2002), Sekhar KR (2002), Seng S (2009), Hast BE (2013), Hoerer S (2013), Baba K (2013), Wang J (2011), Ichimura Y (2013), Baird L (2013), Baird L (2013), Gorrini C (2013), Schaap M (2013), Jiang ZY (2014), Hast BE (2014), Hast BE (2014), Hast BE (2014), Qin S (2014), Buommino E (2012), Kaspar JW (2012), Kaspar JW (2012), Camp ND (2012), Zhang DD (2004), Furukawa M (2005), Khan H (2015), Huo L (2015), Foygel K (2015), Liu K (2015), Lo SC (2006), Kim WD (2012), Kim WD (2012), Kim WD (2012), Zhang Y (2016), Zhang Y (2016), Wu G (2017), Villeneuve NF (2013), Ma J (2012), Ma J (2012), Ma J (2012), Ge W (2017), Ge W (2017), Yoshizaki Y (2017), Yoshizaki Y (2017), Quinti L (2017), Wang Q (2017), Ha Kim K (2017), Yang C (2016), Mulvaney KM (2016), Lu K (2017)	82
CDH1	4	UBC	7	bioid	Guo Z (2014)	1
CDK6	0	KEAP1	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CLU	1	MAP1LC3A	0	affinity chromatography technology	Zhang F (2014)	1
CDK6	0	DDIT3	1	enzymatic study	Anders L (2011)	1
BRCA1	7	GAR1	0	affinity chromatography technology	Hill SJ (2014)	1
TERF1	1	BAG3	4	affinity chromatography technology	Giannone RJ (2010)	1
KEAP1	0	WDR83	1	two hybrid	Rolland T (2014)	1
RAD51	3	TUBG1	2	affinity chromatography technology	Jung YS (2014)	1
KEAP1	0	SASS6	1	affinity chromatography technology	Sowa ME (2009)	1
FERMT3	4	APP	1	pull down	Olah J (2011)	1
KEAP1	0	CHD6	6	affinity chromatography technology	Lu K (2017)	1
TERF1	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
BOD1L1	11	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
ENC1	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Lee H (2015), Lee H (2015)	2
CUL2	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
FBXW11	2	APP	1	affinity chromatography technology	Low TY (2014)	1
CDK20	0	KEAP1	0	affinity chromatography technology, affinity chromatography technology	Wang Q (2017), Wang Q (2017)	2
TERF1	1	ZC3H18	4	two hybrid	Lee OH (2011)	1
BRCA1	7	CASP1	1	affinity chromatography technology, affinity chromatography technology, imaging technique	Dutta D (2015), Dutta D (2015), Dutta D (2015)	3
ENC1	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang DD (2005), Bennett EJ (2010), Huttlin EL (2017)	3
IKBKB	1	EGLN3	0	affinity chromatography technology, pull down, affinity chromatography technology	Xue J (2010), Xue J (2010), Fu J (2013)	3
UBC	7	BTRC	1	affinity chromatography technology, enzymatic study	Matsumoto M (2005), Kumar KG (2007)	2
HSP90AA1	7	ENC1	0	affinity chromatography technology	Taipale M (2012)	1
CUL2	3	HSP90AB1	2	affinity chromatography technology	Bennett EJ (2010)	1
KEAP1	0	MCM3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Hast BE (2013), Hast BE (2014), Hast BE (2014), Mulvaney KM (2016), Mulvaney KM (2016), Mulvaney KM (2016), Mulvaney KM (2016), Lu K (2017), Mulvaney KM (2016)	9
MAP1LC3B	1	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
EGFR	5	UBC	7	affinity chromatography technology, affinity chromatography technology	Tong J (2009), Bishop N (2002)	2
BTRC	1	GPRASP2	0	affinity chromatography technology	Sowa ME (2009)	1
MAD2L1	0	RAF1	3	affinity chromatography technology	Hein MY (2015)	1
MLST8	1	KEAP1	0	affinity chromatography technology	Huttlin EL (2015)	1
BAG3	4	LAMA1	15	affinity chromatography technology	Hein MY (2015)	1
BTRC	1	NFE2L2	1	affinity chromatography technology, bioid	Loveless TB (2015), Coyaud E (2015)	2
CASP1	1	EGFR	5	enzymatic study	Bae SS (2001)	1
CUL3	17	ZC3H18	4	affinity chromatography technology	Bennett EJ (2010)	1
EGFR	5	PRKAG1	1	affinity chromatography technology	Tong J (2014)	1
TUBG1	2	LAMA1	15	affinity chromatography technology	Hein MY (2015)	1
GYPA	0	KEAP1	0	two hybrid	Rolland T (2014)	1
CDH1	4	HSP90AA1	7	affinity chromatography technology	Catimel B (2005)	1
EGFR	5	HSP90AB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Lavictoire SJ (2003), Lavictoire SJ (2003), Foerster S (2013), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
IRF1	0	NPM1	0	affinity chromatography technology, pull down	Narayan V (2011), Narayan V (2011)	2
CCNB1IP1	0	APP	1	pull down	Olah J (2011)	1
UBE2A	0	UBC	7	affinity chromatography technology	Hong JH (2015)	1
CASP1	1	KEAP1	0	affinity chromatography technology	Garstkiewicz M (2017)	1
FAM117B	3	TSC22D2	2	affinity chromatography technology	Huttlin EL (2017)	1
RAF1	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stancato LF (1993), Dogan T (2008), Mollapour M (2010), Du J (2006), Maloney A (2007), Fiskus W (2007), Giommarelli C (2010), Arlander SJ (2006), ONeill E (2004), Taipale M (2012), Zhu J (2005), Schneider C (1996), Mollapour M (2014), Atabakhsh E (2012), Mitra S (2016)	15
MCM2	3	CLU	1	affinity chromatography technology	Drissi R (2015)	1
BRCA1	7	EEF2	11	affinity chromatography technology	Ertych N (2016)	1
FBXW11	2	PFAS	3	affinity chromatography technology	Low TY (2014)	1
USP15	4	USP11	3	affinity chromatography technology	Sowa ME (2009)	1
MCM2	3	HSP90AA1	7	affinity chromatography technology	Drissi R (2015)	1
KEAP1	0	TSC22D4	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Sowa ME (2009), Hast BE (2013), Wang J (2011), Huttlin EL (2015)	4
MAP1LC3A	0	GABARAPL1	0	imaging technique	Tanida I (2006)	1
RAF1	3	BAD	1	enzymatic study, enzymatic study, imaging technique	Jin S (2005), Polzien L (2009), Chen TC (2014)	3
APP	1	CLU	1	pull down, pull down, fluorescent resonance energy transfe, affinity chromatography technology	Hammad SM (1997), Ghiso J (1993), Chen P (2013), Chen P (2013)	4
EGFR	5	ETF1	2	affinity chromatography technology	Tong J (2014)	1
KEAP1	0	FAM117B	3	affinity chromatography technology, two hybrid	Hast BE (2013), Rolland T (2014)	2
XPO1	8	COPG1	5	affinity chromatography technology	Kirli K (2015)	1
IKBKB	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heissmeyer V (2001), Orel L (2010), Tsuchiya Y (2010), Tsuchiya Y (2010)	4
TSC22D2	2	KEAP1	0	affinity chromatography technology	Hast BE (2013)	1
EGLN3	0	GET4	3	affinity chromatography technology	Rodriguez J (2016)	1
BRCA1	7	PGAM5	4	affinity chromatography technology	Hill SJ (2014)	1
PSMD10	1	HSP90AA1	7	affinity chromatography technology	Nanaware PP (2014)	1
KEAP1	0	RELA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid	Yu M (2011), Yu M (2011), Yu M (2011), Yu M (2011), Wang J (2011), Wang J (2011)	6
BTRC	1	CLU	1	affinity chromatography technology	Zoubeidi A (2010)	1
XPO1	8	ETF1	2	affinity chromatography technology	Kirli K (2015)	1
SQSTM1	0	NFE2L2	1	imaging technique	Lau A (2010)	1
AMER1	0	KEAP1	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Major MB (2007), Camp ND (2012), Camp ND (2012), Camp ND (2012), Hast BE (2014), Hast BE (2014)	6
EGFR	5	PDCD6IP	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Schmidt MH (2004), Schmidt MH (2003), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	5
XPO1	8	RAF1	3	affinity chromatography technology	Kirli K (2015)	1
CDH1	4	EEF2	11	bioid	Guo Z (2014)	1
BAG3	4	BCL2	0	affinity chromatography technology	Boiani M (2013)	1
RAF1	3	KEAP1	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM15	0	CTTN	1	affinity chromatography technology, protein complementation assay	Lee OH (2015), Lee OH (2015)	2
BAG3	4	HSP90AB1	2	affinity chromatography technology, biochemical	Chen Y (2013), Kristensen AR (2012)	2
BAG3	4	HSP90AA1	7	affinity chromatography technology	Chen Y (2013)	1
PTMA	2	KEAP1	0	pull down, unspecified method, x-ray crystallography, two hybrid, pull down	Khan H (2013), Khan H (2013), Khan H (2013), Rolland T (2014), Khan H (2015)	5
AMER1	0	RAF1	3	affinity chromatography technology	Boldt K (2016)	1
GABARAPL2	0	KEAP1	0	affinity chromatography technology	Behrends C (2010)	1
GABARAPL1	0	GABARAPL2	0	affinity chromatography technology	Behrends C (2010)	1
EGLN3	0	RELA	1	affinity chromatography technology	Rodriguez J (2016)	1
KEAP1	0	VWA8	5	affinity chromatography technology	Sowa ME (2009)	1
SASS6	1	MED4	2	bioid	Gupta GD (2015)	1
CCNB1IP1	0	CCNB1	3	two hybrid	Toby GG (2003)	1
CUL3	17	KLHL2	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bennett EJ (2010), Takahashi D (2013), Rolland T (2014), Huttlin EL (2017)	4
BCL2	0	BRCA1	7	fluorescent resonance energy transfe, affinity chromatography technology	Laulier C (2011), Laulier C (2011)	2
NFE2L2	1	UBC	7	affinity chromatography technology	Su C (2015)	1
KEAP1	0	SNRPN	0	two hybrid	Wang J (2011)	1
ATG5	0	SQSTM1	0	pull down, affinity chromatography technology	Fracchiolla D (2016), Fracchiolla D (2016)	2
MYH7	3	KEAP1	0	affinity chromatography technology	Hein MY (2015)	1
KLHL3	1	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Ohta A (2013), Ohta A (2013), Wakabayashi M (2013), Ji AX (2013), Shibata S (2013), Shibata S (2013), Takahashi D (2013), McCormick JA (2014), Rolland T (2014), Ibeawuchi SR (2015), Schumacher FR (2015), Schumacher FR (2015), Wu G (2013)	13
CUL3	17	IKBKB	1	affinity chromatography technology	Lee DF (2009)	1
BAG3	4	WDR1	3	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
KEAP1	0	MAD2L1	0	affinity chromatography technology, affinity chromatography technology, two hybrid	Sowa ME (2009), Hast BE (2013), Rolland T (2014)	3
MCM2	3	USP15	4	affinity chromatography technology	Boldt K (2016)	1
KEAP1	0	ZSCAN32	10	two hybrid	Rolland T (2014)	1
TUBG1	2	HSP90AA1	7	biochemical, affinity chromatography technology, affinity chromatography technology	Wigley WC (1999), Fogeron ML (2013), Hein MY (2015)	3
ZRANB1	3	PGAM5	4	affinity chromatography technology	Sowa ME (2009)	1
MCMBP	3	MCM3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Jagannathan M (2014), Taipale M (2014), Taipale M (2014), Wan C (2015), Huttlin EL (2017), Mulvaney KM (2016)	6
KEAP1	0	EEF2	11	affinity chromatography technology	Lu K (2017)	1
CUL3	17	HSP90AB1	2	affinity chromatography technology	Bennett EJ (2010)	1
GABARAPL2	0	TMEM160	0	affinity chromatography technology	Behrends C (2010)	1
UBC	7	CLU	1	pull down	Zoubeidi A (2010)	1
KEAP1	0	CDH1	4	affinity chromatography technology, affinity chromatography technology, pull down, bioid	Kim WD (2012), Kim WD (2012), Kim WD (2012), Guo Z (2014)	4
UBC	7	PDCD6IP	3	pull down	Zhang X (2017)	1
SQSTM1	0	GABARAPL1	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, two hybrid	Rual JF (2005), Behrends C (2010), Wild P (2011), Kirkin V (2009), Zhang Y (2011), Zhang Y (2011), Rolland T (2014)	7
EEF2	11	XPO1	8	biochemical	Kristensen AR (2012)	1
CLU	1	KEAP1	0	two hybrid	Wang J (2011)	1
CCNB1	3	RELA	1	affinity chromatography technology	Felzien LK (1998)	1
EGLN3	0	RAF1	3	affinity chromatography technology	Rodriguez J (2016)	1
CPEB2	7	EEF2	11	two hybrid, affinity chromatography technology, affinity chromatography technology	Chen PJ (2012), Chen PJ (2012), Chen PJ (2012)	3
MCM2	3	EEF2	11	affinity chromatography technology	Drissi R (2015)	1
EGFR	5	IPO11	0	affinity chromatography technology, affinity chromatography technology	Foerster S (2013), Tong J (2014)	2
MAP1LC3B	1	MAP1LC3A	0	affinity chromatography technology	Behrends C (2010)	1
MCM2	3	KPNA6	1	affinity chromatography technology	Drissi R (2015)	1
SSH3	3	APP	1	pull down	Olah J (2011)	1
BRCA1	7	HSP90AB1	2	affinity chromatography technology	Ertych N (2016)	1
HSP90AB1	2	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
EGLN3	0	MCMBP	3	affinity chromatography technology	Rodriguez J (2016)	1