PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TRIM25	5	LASP1	1	affinity chromatography technology	Choudhury NR (2017)	1
RBPMS	0	C1orf94	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RETREG3	4	PLSCR1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ELAVL1	0	RETREG3	4	affinity chromatography technology	Abdelmohsen K (2009)	1
POLI	5	UBB	4	two hybrid	Plosky BS (2006)	1
ATXN1L	0	RBFOX2	5	two hybrid	Lim J (2006)	1
TRIM25	5	RABGEF1	1	affinity chromatography technology	Choudhury NR (2017)	1
UBC	7	UBASH3A	3	pull down, pull down, pull down	Kowanetz K (2004), Ikeda F (2007), Hoeller D (2006)	3
ATXN1	2	RBPMS	0	two hybrid, affinity chromatography technology, two hybrid	Lim J (2006), Lim J (2006), Rolland T (2014)	3
ROR2	0	C1orf94	1	two hybrid	Rolland T (2014)	1
SEPT2	4	DAZAP2	1	two hybrid	Rual JF (2005)	1
TRIM25	5	NOTCH1	25	affinity chromatography technology	Choudhury NR (2017)	1
RABGEF1	1	TAX1BP1	3	affinity chromatography technology	Huttlin EL (2017)	1
DAZAP2	1	UBA52	0	two hybrid	Vinayagam A (2011)	1
DAZAP2	1	DAZ1	0	pull down, two hybrid, pull down	Tsui S (2000), Tsui S (2000), Tsui S (2000)	3
TRIM25	5	DAZAP2	1	affinity chromatography technology	Choudhury NR (2017)	1
EPN1	4	PLEKHB2	4	two hybrid	Rolland T (2014)	1
TRIM25	5	FAM168A	0	affinity chromatography technology	Choudhury NR (2017)	1
DAZAP2	1	POGZ	49	two hybrid	Rolland T (2014)	1
UBC	7	TOLLIP	3	pull down, pull down, pull down, biochemical, pull down, pull down, pull down, pull down	Fenner BJ (2009), Nathan JA (2013), Mitra S (2013), Mitra S (2013), Shih SC (2003), Lu K (2014), Lu K (2014), Zhang X (2017)	8
UBC	7	PEF1	0	affinity chromatography technology, affinity chromatography technology	Matsumoto M (2005), McGourty CA (2016)	2
NOTCH1	25	EPN1	4	affinity chromatography technology	Sorensen EB (2010)	1
RETREG3	4	DAZAP2	1	affinity chromatography technology	Huttlin EL (2017)	1
DAZAP2	1	LEF1	3	affinity chromatography technology, affinity chromatography technology	Lukas J (2009), Lukas J (2009)	2
CALCOCO2	0	PEF1	0	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
ELAVL1	0	OTULIN	0	affinity chromatography technology	Abdelmohsen K (2009)	1
UBQLN4	2	HGS	5	two hybrid	Lim J (2006)	1
HGS	5	STAM2	0	two hybrid, biochemical, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Rual JF (2005), Bache KG (2003), Bache KG (2003), Mizuno E (2004), Kanazawa C (2003), Kanazawa C (2003), Stuible M (2010), Havugimana PC (2012), Hoeller D (2006), Wan C (2015)	10
MAP3K7	2	DAZAP2	1	affinity chromatography technology	Winkel A (2008)	1
ATXN1	2	ARID5A	4	two hybrid, two hybrid	Lim J (2006), Suter B (2013)	2
DAZAP2	1	UBASH3B	4	two hybrid	Rolland T (2014)	1
DAZAP2	1	DCUN1D1	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
STAT6	1	WWP1	3	two hybrid	Ravasi T (2010)	1
NDUFA5	0	DAZAP2	1	two hybrid	Rual JF (2005)	1
ATXN1	2	RHOXF2	0	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
MAGED1	0	RBPMS	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	PRR20A	0	two hybrid	Rolland T (2014)	1
SMURF2	3	UBC	7	enzymatic study, affinity chromatography technology, enzymatic study, pull down, pull down	Maspero E (2013), Zhang L (2013), Kristariyanto YA (2015), Mari S (2014), Zhang Y (2017)	5
CALCOCO2	0	FAM168A	0	two hybrid	Rolland T (2014)	1
TRIM25	5	ELAVL1	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
DAB1	1	ARID5A	4	two hybrid	Rolland T (2014)	1
TRIM25	5	CTNNB1	30	affinity chromatography technology	Choudhury NR (2017)	1
HGS	5	POGZ	49	two hybrid	Rolland T (2014)	1
RNF115	1	TAX1BP1	3	affinity chromatography technology	Huttlin EL (2017)	1
LMO2	2	C1orf94	1	two hybrid	Rolland T (2014)	1
UBC	7	EPN1	4	pull down, pull down, pull down, pull down	Fenner BJ (2009), Nathan JA (2013), Hawryluk MJ (2006), Zhang X (2017)	4
DAZAP2	1	AATF	0	two hybrid	Rual JF (2005)	1
UBASH3B	4	RPS27A	1	affinity chromatography technology	Li J (2013)	1
SQSTM1	0	TAX1BP1	3	affinity chromatography technology	Mildenberger J (2017)	1
CALCOCO2	0	POLI	5	two hybrid	Rual JF (2005)	1
DAZAP2	1	RNF115	1	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
CLASRP	1	ATXN1L	0	affinity chromatography technology	Huttlin EL (2017)	1
CALCOCO2	0	ZNF581	0	two hybrid	Rolland T (2014)	1
SQSTM1	0	UBC	7	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, affinity chromatography technology, unspecified method, pull down, pull down, pull down, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, imaging technique, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Vinayagam A (2011), Vadlamudi RK (1996), Tanji K (2012), Matsumoto G (2011), Long J (2008), Long J (2008), Najat D (2009), Najat D (2009), Hocking LJ (2004), Boh BK (2011), Long J (2010), Seibenhener ML (2004), Seibenhener ML (2004), Seibenhener ML (2004), Fenner BJ (2009), Nathan JA (2013), Ciani B (2003), Shi J (2013), Goode A (2014), Bish RA (2007), Lu K (2014), Zhou L (2014), Zhou L (2014), Vadlamudi RK (1996), Long J (2008), Cavey JR (2006), Cavey JR (2006), Kirkin V (2009), Nakayasu ES (2013), Nakayasu ES (2013), Lim J (2015), Milan E (2015), Milan E (2015), Ordureau A (2015), Wurzer B (2015), Zhang X (2017), Wang L (2017), Liu X (2017), Peng H (2017), Donohue E (2014), Nibe Y (2017), Nibe Y (2017), Govindaraju VK (2017)	43
DAZAP2	1	COL4A2	2	two hybrid	Vinayagam A (2011)	1
CALCOCO2	0	SQSTM1	0	affinity chromatography technology	Cemma M (2011)	1
MAGED1	0	DAZAP2	1	two hybrid	Yu H (2011)	1
NOTCH1	25	DAZAP2	1	two hybrid	Daakour S (2016)	1
RBPMS	0	KRTAP8-1	0	two hybrid	Rolland T (2014)	1
RBFOX1	1	DAB1	1	two hybrid	Corominas R (2014)	1
FAM168A	0	C1orf94	1	two hybrid	Rolland T (2014)	1
ATXN1	2	TOLLIP	3	two hybrid	Lim J (2006)	1
MAGED1	0	AATF	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Di Certo MG (2007), Di Certo MG (2007), Di Certo MG (2007)	3
HGS	5	NOTCH1	25	affinity chromatography technology	Sjoeqvist M (2014)	1
UBQLN4	2	C1orf94	1	two hybrid	Lim J (2006)	1
UBE2D4	0	TRIM25	5	two hybrid	Markson G (2009)	1
BAG3	4	DAZAP2	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
BAG3	4	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gamerdinger M (2009), Gamerdinger M (2009), Chen Y (2013)	3
TRIM25	5	NEDD4L	3	affinity chromatography technology	Choudhury NR (2017)	1
RBPMS	0	RBFOX2	5	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Huttlin EL (2015), Huttlin EL (2017)	3
ATXN1L	0	RBPMS	0	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
C1orf94	1	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	ZC3H10	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
TOLLIP	3	RBFOX2	5	two hybrid	Bandyopadhyay S (2010)	1
STAM2	0	VPS37C	3	two hybrid	Rolland T (2014)	1
UBE2D4	0	RNF115	1	two hybrid, two hybrid	van Wijk SJ (2009), Rolland T (2014)	2
UBC	7	ZFYVE9	5	pull down	Kostaras E (2012)	1
PLSCR1	0	VPS37C	3	two hybrid	Rolland T (2014)	1
ZFYVE9	5	STAM2	0	affinity chromatography technology	Kostaras E (2012)	1
RBFOX1	1	FAM168A	0	two hybrid	Corominas R (2014)	1
ELAVL1	0	COL4A5	2	affinity chromatography technology	Abdelmohsen K (2009)	1
TRIM25	5	TLE1	6	affinity chromatography technology	Choudhury NR (2017)	1
UBC	7	CALCOCO2	0	pull down, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, pull down, affinity chromatography technology, imaging technique, pull down, imaging technique	Fenner BJ (2009), Fenner BJ (2009), Rolland T (2014), Tumbarello DA (2015), Xie X (2015), Xie X (2015), Xie X (2015), Xie X (2015), Ordureau A (2015), Minowa-Nozawa A (2017)	10
TAX1BP1	3	FAM168A	0	two hybrid	Rolland T (2014)	1
MAGED1	0	SMAP2	4	two hybrid	Rolland T (2014)	1
IL17RB	0	DAZAP2	1	affinity chromatography technology	Popova A (2012)	1
DAB1	1	ROR2	0	two hybrid	Rolland T (2014)	1
DAB1	1	MAGED1	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	WWP1	3	two hybrid	Rual JF (2005)	1
DAB1	1	ZC3H10	1	two hybrid	Rolland T (2014)	1
RBPMS	0	FAM168A	0	two hybrid	Rolland T (2014)	1
DAB1	1	RHOXF2	0	two hybrid	Rolland T (2014)	1
FAM168A	0	PRR20A	0	two hybrid	Rolland T (2014)	1
PEF1	0	DAZAP2	1	two hybrid	Venkatesan K (2009)	1
DAZAP2	1	ZFAND2B	1	two hybrid, two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009), Rolland T (2014)	3
DAZAP2	1	ZNF34	2	two hybrid	Rolland T (2014)	1
DAB1	1	RBFOX2	5	two hybrid	Rolland T (2014)	1
RBFOX1	1	ATXN1	2	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
RBPMS	0	RHOXF2	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
TRIM25	5	USP5	2	affinity chromatography technology	Choudhury NR (2017)	1
ELAVL1	0	RNF115	1	affinity chromatography technology	Abdelmohsen K (2009)	1
POLI	5	UBC	7	two hybrid, two hybrid, far western blotting, x-ray crystallography, pull down, far western blotting	Plosky BS (2006), Plosky BS (2006), McIntyre J (2012), Bomar MG (2010), Plosky BS (2006), McIntyre J (2012)	6
CXCL12	0	DAZAP2	1	two hybrid	Wang J (2011)	1
DAB1	1	PRR20A	0	two hybrid	Rolland T (2014)	1
TCF7L2	12	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lukas J (2009), Idogawa M (2007), Hong CF (2009), Del Valle-Perez B (2011), Tzeng SL (2006), Tzeng SL (2006), Satow R (2012), Satow R (2012), Graham TA (2001), Sato S (2005), Mosimann C (2006), Shekhar MP (2006), Hsu MC (2007), Loregger A (2015), Hanson AJ (2012), Kuslansky Y (2016)	16
POGZ	49	PRR20A	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	CEP70	1	two hybrid	Vinayagam A (2011)	1
ATXN1	2	C1orf94	1	two hybrid, affinity chromatography technology, two hybrid	Lim J (2006), Lim J (2006), Rolland T (2014)	3
DAZAP2	1	TLE1	6	two hybrid	Vinayagam A (2011)	1
UBC	7	UBAC1	2	pull down	Zhang X (2017)	1
CTNNB1	30	LEF1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Edlund S (2005), Grueneberg DA (2003), Behrens J (1996), Behrens J (1996), Labbe E (2000), Sierra J (2006), Gomes NP (2006), Vietor I (2005), Billin AN (2000), Fischer L (2002), Tutter AV (2001), Sadot E (2002), Feigin ME (2008), Daniels DL (2005), Porfiri E (1997), Porfiri E (1997), Hamada F (2004), Vadlamudi U (2005), Lu D (2012), Lu D (2012)	20
DAZAP2	1	CTNNB1	30	affinity chromatography technology	Lukas J (2009)	1
UBC	7	NEDD4L	3	x-ray crystallography, enzymatic study, enzymatic study, enzymatic study	Kamadurai HB (2009), Sheng Y (2012), Maspero E (2013), Michel MA (2015)	4
UBC	7	MAP3K7	2	pull down	Zhang X (2017)	1
UBC	7	UBASH3B	4	pull down, pull down, affinity chromatography technology, pull down, pull down	Kowanetz K (2004), Ikeda F (2007), Brehme M (2009), Hoeller D (2006), Zhang X (2017)	5
TCF7L2	12	LEF1	3	affinity chromatography technology	Jia Y (2014)	1
DAZAP2	1	RHOXF2	0	two hybrid, two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009), Rolland T (2014)	3
RBM11	0	RHOXF2	0	two hybrid	Rual JF (2005)	1
PLSCR1	0	EXD3	3	two hybrid	Rual JF (2005)	1
DAZAP2	1	MED31	0	two hybrid	Vinayagam A (2011)	1
RPS27A	1	DAZAP2	1	two hybrid	Rolland T (2014)	1
TRIM25	5	UBAC1	2	affinity chromatography technology	Choudhury NR (2017)	1
HGS	5	DAZAP2	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RBFOX1	1	MAGED1	0	two hybrid, two hybrid	Lim J (2006), Corominas R (2014)	2
DAB1	1	TOLLIP	3	two hybrid	Rolland T (2014)	1
CLASRP	1	RHOXF2	0	two hybrid	Rual JF (2005)	1
DAZAP2	1	UBAC1	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ELAVL1	0	DAZAP2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
UBC	7	RABGEF1	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, two hybrid, pull down, pull down, pull down	Mattera R (2004), La Rosa P (2011), Kalesnikoff J (2007), Penengo L (2006), Sokratous K (2012), Rolland T (2014), Mattera R (2006), Zhang X (2017), Kristariyanto YA (2017)	9
DAZAP2	1	TCF7L2	12	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Lukas J (2009), Lukas J (2009), Lukas J (2009), Lukas J (2009)	4
PLEKHB2	4	C1orf94	1	two hybrid	Rolland T (2014)	1
DAZAP2	1	SMURF2	3	affinity chromatography technology, two hybrid	Popova A (2012), Colland F (2004)	2
MAGED1	0	RHOXF2	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	RBPMS	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ZC3H10	1	DAZAP2	1	two hybrid	Venkatesan K (2009)	1
ZFYVE9	5	DAZAP2	1	two hybrid	Colland F (2004)	1
TRIM25	5	RPS27A	1	affinity chromatography technology, affinity chromatography technology	Pauli EK (2014), Choudhury NR (2017)	2
ELAVL1	0	NEDD4L	3	affinity chromatography technology	Abdelmohsen K (2009)	1
TRIM25	5	RBFOX2	5	affinity chromatography technology	Choudhury NR (2017)	1
RBFOX1	1	PRR20A	0	two hybrid	Corominas R (2014)	1
DAZAP2	1	CDK4	2	two hybrid	Vinayagam A (2011)	1
DAZAP2	1	C1orf94	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
HIP1	4	DAZAP2	1	two hybrid	Rolland T (2014)	1
DAZAP2	1	COL4A5	2	two hybrid	Vinayagam A (2011)	1
DAZAP2	1	CLASRP	1	two hybrid	Rolland T (2014)	1
UBASH3B	4	UBASH3A	3	affinity chromatography technology	Brehme M (2009)	1
PLSCR1	0	ZNF581	0	two hybrid	Rual JF (2005)	1
TAX1BP1	3	DAZAP2	1	two hybrid	Rolland T (2014)	1
DAZAP2	1	ARID5A	4	two hybrid	Rolland T (2014)	1
LASP1	1	PLSCR1	0	two hybrid	Rual JF (2005)	1
NEDD4L	3	UBE2E2	1	pull down	Todaro DR (2017)	1
RBFOX1	1	RBFOX2	5	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
GDE1	1	DAZAP2	1	affinity chromatography technology	Huttlin EL (2017)	1
DAZAP2	1	TCF7	1	affinity chromatography technology, affinity chromatography technology	Lukas J (2009), Lukas J (2009)	2
DAZAP2	1	RBFOX2	5	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	4
ROR2	0	MAGED1	0	affinity chromatography technology	Matsuda T (2003)	1
DAZAP2	1	FAM168A	0	two hybrid	Rolland T (2014)	1
FAM168A	0	VPS37C	3	two hybrid	Rolland T (2014)	1
EPN1	4	MED31	0	two hybrid	Stelzl U (2005)	1
ZFAND2B	1	UBB	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBFOX1	1	RBPMS	0	two hybrid, two hybrid	Corominas R (2014), Rolland T (2014)	2
TRIM25	5	SQSTM1	0	affinity chromatography technology	Choudhury NR (2017)	1
FAM168A	0	OTULIN	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	OPTN	1	two hybrid	Rolland T (2014)	1
DAZAP2	1	RNF208	1	two hybrid	Rolland T (2014)	1
DAZAP2	1	SMAP2	4	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
DAB1	1	SMAP2	4	two hybrid	Rolland T (2014)	1
CTNNB1	30	TCF7L1	1	x-ray crystallography, unspecified method	Graham TA (2000), Xing Y (2004)	2
DAZAP2	1	ZNF581	0	two hybrid	Rual JF (2005)	1
TOLLIP	3	NEDD4L	3	affinity chromatography technology	Li S (2011)	1
FAM46C	3	RHOXF2	0	two hybrid	Rolland T (2014)	1
NOTCH1	25	LEF1	3	pull down	Ross DA (2001)	1
NEDD4L	3	HGS	5	enzymatic study, affinity chromatography technology	Persaud A (2009), Zhou R (2010)	2
USP5	2	DAZAP2	1	two hybrid	Rolland T (2014)	1
UBQLN4	2	STAM2	0	two hybrid	Lim J (2006)	1
ATXN1	2	DAZAP2	1	two hybrid, affinity chromatography technology	Lim J (2006), Lim J (2006)	2
RBFOX1	1	C1orf94	1	two hybrid, two hybrid	Corominas R (2014), Rolland T (2014)	2
MAGED1	0	KRTAP19-5	0	two hybrid	Rolland T (2014)	1
UBAC1	2	RPS27A	1	affinity chromatography technology	Huttlin EL (2017)	1
DAZAP2	1	FAM46C	3	two hybrid	Rual JF (2005)	1
ELAVL1	0	TOLLIP	3	affinity chromatography technology	Abdelmohsen K (2009)	1
DAB1	1	POGZ	49	two hybrid	Rolland T (2014)	1
DAZAP2	1	FBN3	13	two hybrid	Vinayagam A (2011)	1
UBB	4	CALCOCO2	0	two hybrid, affinity chromatography technology	Rolland T (2014), Huttlin EL (2017)	2
SQSTM1	0	NOTCH1	25	affinity chromatography technology, affinity chromatography technology	Ahn JS (2016), Ahn JS (2016)	2
ZFAND2B	1	UBC	7	affinity chromatography technology, pull down	Braunstein I (2015), Zhang X (2017)	2
DAB1	1	DAZAP2	1	two hybrid	Rolland T (2014)	1
UBC	7	TAX1BP1	3	pull down, x-ray crystallography, pull down, pull down	Fenner BJ (2009), Tumbarello DA (2015), Tumbarello DA (2015), Zhang X (2017)	4
AATF	0	NEDD4L	3	two hybrid	Wang J (2011)	1
ROR2	0	MAP3K7	2	affinity chromatography technology, enzymatic study	Winkel A (2008), Winkel A (2008)	2
ATXN1	2	FAM46B	2	two hybrid, two hybrid	Lim J (2006), Suter B (2013)	2
TOLLIP	3	PRR20A	0	two hybrid	Rolland T (2014)	1
NEDD4L	3	AICDA	0	enzymatic study	Persaud A (2009)	1
NEDD4L	3	UBAC1	2	enzymatic study, pull down	Persaud A (2009), Persaud A (2009)	2
USP5	2	UBC	7	pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, unspecified method, affinity chromatography technology, pull down, x-ray crystallography, pull down, pull down, pull down, enzymatic study, enzymatic study, pull down, pull down	Reyes-Turcu FE (2008), Nicassio F (2007), Zhang YH (2012), Bremm A (2010), Komander D (2009), Melandri F (1996), Sokratous K (2012), Fenner BJ (2009), Schulz S (2012), Raasi S (2005), Nathan JA (2013), Ernst A (2013), Bish RA (2007), Reyes-Turcu FE (2006), Reyes-Turcu FE (2006), Zhang YH (2012), Liu Y (2014), Scott D (2015), Flierman D (2016), Castaneda CA (2016), Zhang X (2017), Kwasna D (2018)	22
ATXN1	2	RBFOX2	5	two hybrid, affinity chromatography technology, two hybrid, two hybrid	Lim J (2006), Lim J (2006), Suter B (2013), Rolland T (2014)	4
DAZAP2	1	RABGEF1	1	two hybrid	Rolland T (2014)	1
DAB1	1	C1orf94	1	two hybrid	Rolland T (2014)	1
MAGED1	0	RBFOX2	5	two hybrid	Rolland T (2014)	1
TLE1	6	CTNNB1	30	pull down	Levanon D (1998)	1
TAX1BP1	3	TNIP3	3	two hybrid	Rolland T (2014)	1
RBPMS	0	VPS37C	3	two hybrid	Rolland T (2014)	1
RBFOX1	1	RHOXF2	0	two hybrid, affinity chromatography technology, two hybrid	Lim J (2006), Lim J (2006), Corominas R (2014)	3
TRIM25	5	HIP1	4	affinity chromatography technology	Choudhury NR (2017)	1
PLSCR1	0	DAZAP2	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
DAZAP2	1	CCDC120	1	two hybrid	Rual JF (2005)	1
DAZAP2	1	VPS37C	3	two hybrid	Rolland T (2014)	1
LMO2	2	CALCOCO2	0	two hybrid	Rolland T (2014)	1
ELAVL1	0	UBASH3B	4	affinity chromatography technology	Abdelmohsen K (2009)	1
TOLLIP	3	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Lu K (2014), Jongsma ML (2016)	2
DCUN1D1	0	UBC	7	affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Huang G (2014), Huang G (2014)	3
ELAVL1	0	FAM46C	3	affinity chromatography technology	Abdelmohsen K (2009)	1
UBC	7	VPS37C	3	pull down	Nathan JA (2013)	1
FAM46B	2	DAZAP2	1	two hybrid	Venkatesan K (2009)	1
UBB	4	DAZAP2	1	two hybrid, two hybrid, two hybrid	Rual JF (2005), Rolland T (2014), Yu H (2011)	3
RBFOX2	5	C1orf94	1	two hybrid	Rolland T (2014)	1
ARID5A	4	RHOXF2	0	two hybrid	Rolland T (2014)	1
TOLLIP	3	RHOXF2	0	two hybrid, two hybrid	Rual JF (2005), Xin X (2009)	2
ARID5A	4	RBPMS	0	two hybrid	Rolland T (2014)	1
LMO2	2	DAZAP2	1	two hybrid	Rual JF (2005)	1
RNF115	1	UBC	7	two hybrid, pull down, protein complementation assay, pull down	Amemiya Y (2008), Amemiya Y (2008), Amemiya Y (2008), Amemiya Y (2008)	4
PLSCR1	0	NOC4L	3	two hybrid	Rual JF (2005)	1
UBC	7	DAZAP2	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
TAX1BP1	3	OPTN	1	affinity chromatography technology, affinity chromatography technology	Journo C (2009), Journo C (2009)	2
RPS27A	1	UBA52	0	biochemical	Wan C (2015)	1
DAZAP2	1	NOC4L	3	two hybrid	Rual JF (2005)	1
ROR2	0	PRR20A	0	two hybrid	Rolland T (2014)	1
WWP1	3	UBC	7	enzymatic study	Kristariyanto YA (2015)	1
WWP1	3	NOTCH1	25	pull down, imaging technique	Flasza M (2006), Flasza M (2006)	2
UBQLN4	2	UBC	7	pull down	Su V (2010)	1
RBPMS	0	ZNF581	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
LASP1	1	RHOXF2	0	two hybrid	Rolland T (2014)	1
RBPMS	0	TOLLIP	3	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
DAZAP2	1	STAM2	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
OPTN	1	UBC	7	affinity chromatography technology, pull down, pull down, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down, pull down	Wild P (2011), Fenner BJ (2009), Zhu G (2007), Zhu G (2007), Wagner S (2008), Gleason CE (2011), Nagabhushana A (2011), Korac J (2012), Wild P (2011), Tumbarello DA (2015), Heo JM (2015), Ordureau A (2015), Richter B (2016), Richter B (2016), Nakazawa S (2016), Zhang X (2017), Kliza K (2017), Bansal M (2018)	18
STAM2	0	UBC	7	x-ray crystallography, x-ray crystallography, pull down, pull down, pull down, pull down, pull down	Lange A (2010), Lange A (2012), Lange A (2012), Stuible M (2010), Baiady N (2016), Zhang X (2017), Hologne M (2016)	7
ZFYVE9	5	CTNNB1	30	two hybrid	Colland F (2004)	1
RHOXF2	0	FAM46B	2	two hybrid	Rual JF (2005)	1
DAZAP2	1	EPN1	4	two hybrid	Rolland T (2014)	1
BAG3	4	FAM168A	0	affinity chromatography technology	Chen Y (2013)	1
OPTN	1	SQSTM1	0	affinity chromatography technology, pull down	Liu Z (2014), Liu Z (2014)	2
ATXN1	2	ZC3H10	1	two hybrid, two hybrid	Lim J (2006), Suter B (2013)	2
ATXN1L	0	HGS	5	two hybrid	Lim J (2006)	1
SMAP2	4	C1orf94	1	two hybrid	Rolland T (2014)	1
ATXN1L	0	ATXN1	2	two hybrid, affinity chromatography technology, two hybrid	Mizutani A (2005), Mizutani A (2005), Lim J (2006)	3
MAGED1	0	MAP3K7	2	affinity chromatography technology, affinity chromatography technology	Kang J (2014), Kang J (2014)	2
RPS27A	1	CALCOCO2	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	SQSTM1	0	two hybrid	Vinayagam A (2011)	1
DAB1	1	KRTAP19-5	0	two hybrid	Rolland T (2014)	1
MAGED1	0	C1orf94	1	two hybrid	Rolland T (2014)	1
ROR2	0	RBPMS	0	two hybrid	Rolland T (2014)	1
RHOXF2	0	KRTAP19-5	0	two hybrid	Rolland T (2014)	1
ATXN1	2	LASP1	1	two hybrid	Suter B (2013)	1
NEDD4L	3	NOTCH1	25	affinity chromatography technology	Puca L (2013)	1
VPS37C	3	C1orf94	1	two hybrid	Rolland T (2014)	1
HGS	5	UBC	7	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down	Mizuno E (2006), Raiborg C (2002), Raiborg C (2002), Nathan JA (2013), Nathan JA (2013), Bishop N (2002), Stuible M (2010), Oved S (2006), Hoeller D (2006), Kharitidi D (2015), Zhang X (2017)	11
CTNNB1	30	ELAVL1	0	pull down	Kim I (2012)	1
HGS	5	PEF1	0	two hybrid	Rolland T (2014)	1
GDE1	1	PLSCR1	0	affinity chromatography technology	Huttlin EL (2015)	1
DAZAP2	1	PLEKHB2	4	two hybrid	Rolland T (2014)	1
ATXN1L	0	DAZAP2	1	two hybrid	Lim J (2006)	1
ATXN1	2	STAM2	0	two hybrid	Suter B (2013)	1
ELAVL1	0	UBE2E2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ATXN1	2	CLASRP	1	two hybrid, affinity chromatography technology	Lim J (2006), Huttlin EL (2017)	2
RBPMS	0	TEX37	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RBFOX2	5	RHOXF2	0	two hybrid	Rual JF (2005)	1
ELAVL1	0	RBFOX2	5	affinity chromatography technology, two hybrid, two hybrid	Abdelmohsen K (2009), Hegele A (2012), Hegele A (2012)	3
DAZAP2	1	POLI	5	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
RBPMS	0	PRR20A	0	two hybrid	Rolland T (2014)	1
RBPMS	0	POGZ	49	two hybrid	Rolland T (2014)	1
SQSTM1	0	NDUFA5	0	affinity chromatography technology	Milan E (2015)	1
ELAVL1	0	TCF7L2	12	affinity chromatography technology	Abdelmohsen K (2009)	1
DAZAP2	1	GPSM1	1	two hybrid	Rual JF (2005)	1
DAZAP2	1	NEDD4L	3	two hybrid	Rolland T (2014)	1
LASP1	1	DAZAP2	1	two hybrid	Venkatesan K (2009)	1
CLCC1	4	DAZAP2	1	affinity chromatography technology	Huttlin EL (2017)	1
UBE2E2	1	DAZAP2	1	two hybrid	Rolland T (2014)	1
DAZAP2	1	VHLL	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	UBASH3A	3	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
DAZAP2	1	KRTAP19-5	0	two hybrid	Rolland T (2014)	1
FAM168A	0	UBASH3B	4	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
NOTCH1	25	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down	Jin YH (2009), Jin YH (2009), Jin YH (2009)	3
DAZAP2	1	TCF7L1	1	affinity chromatography technology, affinity chromatography technology	Lukas J (2009), Lukas J (2009)	2
STAT6	1	DAZAP2	1	two hybrid	Ravasi T (2010)	1
DAZL	0	DAZ1	0	two hybrid, pull down, two hybrid	Ruggiu M (2000), Tsui S (2000), Moore FL (2003)	3
RBPMS	0	KRTAP19-5	0	two hybrid	Rolland T (2014)	1
ROR2	0	DAZAP2	1	affinity chromatography technology, two hybrid	Winkel A (2008), Rolland T (2014)	2
CLCC1	4	PLSCR1	0	affinity chromatography technology	Huttlin EL (2017)	1
FAM168A	0	SMAP2	4	two hybrid	Rolland T (2014)	1
DAB1	1	CLASRP	1	two hybrid	Rolland T (2014)	1
DAB1	1	FAM168A	0	two hybrid	Rolland T (2014)	1
AICDA	0	DAZAP2	1	affinity chromatography technology	Delker RK (2013)	1
NOTCH1	25	MAGED1	0	two hybrid	Daakour S (2016)	1
DAZAP2	1	CALCOCO2	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
ATXN1	2	UBQLN4	2	two hybrid, two hybrid	Davidson JD (2000), Lim J (2006)	2
MAGED1	0	BAG3	4	two hybrid	Rolland T (2014)	1
DAB1	1	KRTAP8-1	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	TOLLIP	3	two hybrid, two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009), Rolland T (2014)	3
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
CALCOCO2	0	TAX1BP1	3	affinity chromatography technology, two hybrid	Morriswood B (2007), Morriswood B (2007)	2
TRIM25	5	PLEKHB2	4	affinity chromatography technology	Choudhury NR (2017)	1
TLE1	6	LEF1	3	pull down, pull down, x-ray crystallography	Levanon D (1998), Daniels DL (2005), Daniels DL (2005)	3
MAP3K7	2	HGS	5	pull down	Sasaki Y (2001)	1
STAM2	0	PLEKHB2	4	two hybrid	Rolland T (2014)	1
DAZAP2	1	DAZAP2	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
RBFOX1	1	DAZAP2	1	two hybrid	Corominas R (2014)	1
DAZAP2	1	EXD3	3	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
DAZAP2	1	OTULIN	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	UBE2D4	0	two hybrid	Rolland T (2014)	1
OTULIN	0	UBC	7	enzymatic study, x-ray crystallography, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down	Keusekotten K (2013), Keusekotten K (2013), Rivkin E (2013), Schaeffer V (2014), Mevissen TE (2013), Wauer T (2015), Kliza K (2017), Kwasna D (2018)	8
TRIM25	5	UBASH3B	4	affinity chromatography technology	Choudhury NR (2017)	1
DAZAP2	1	DAZL	0	pull down	Tsui S (2000)	1
UBC	7	TNIP3	3	affinity chromatography technology, two hybrid	Wagner S (2008), Wagner S (2008)	2
RBM11	0	DAZAP2	1	two hybrid	Yu H (2011)	1
ATXN1	2	PRR20A	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	TEX37	1	two hybrid	Rolland T (2014)	1
ATXN1	2	BATF2	0	two hybrid	Lim J (2006)	1
BAG3	4	PEF1	0	affinity chromatography technology, affinity chromatography technology	Chen Y (2013), Chen Y (2013)	2
DAZAP2	1	BATF2	0	two hybrid, two hybrid	Rual JF (2005), Venkatesan K (2009)	2
DAZAP2	1	WDR73	2	two hybrid	Vinayagam A (2011)	1
VPS37C	3	HGS	5	two hybrid, two hybrid	Eastman SW (2005), Rolland T (2014)	2
UBAC1	2	UBB	4	affinity chromatography technology	Huttlin EL (2017)	1
RBPMS	0	VHLL	0	two hybrid	Rolland T (2014)	1
DAZAP2	1	TNIP3	3	two hybrid	Rolland T (2014)	1
TOLLIP	3	MAGED1	0	affinity chromatography technology	Li S (2011)	1
UBQLN4	2	DAZAP2	1	two hybrid	Lim J (2006)	1
DAZAP2	1	KRTAP8-1	0	two hybrid	Rolland T (2014)	1
ZC3H10	1	PRR20A	0	two hybrid	Rolland T (2014)	1
SMURF2	3	UBA52	0	affinity chromatography technology	Zhang L (2013)	1