PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CDH1	4	TRIM25	5	bioid	Guo Z (2014)	1
SRC	2	GAB2	3	affinity chromatography technology	Zhao C (1999)	1
NCK1	0	GAB2	3	pull down	Zhao C (1999)	1
SRC	2	FYN	1	unspecified method, affinity chromatography technology, affinity chromatography technology	Pirozzi G (1997), Chen Y (2009), Huttlin EL (2017)	3
NXF1	0	SHC1	0	affinity chromatography technology	Castello A (2012)	1
AES	2	ABI2	4	two hybrid	Rolland T (2014)	1
SGTB	2	ARHGAP32	11	affinity chromatography technology	Hein MY (2015)	1
SRC	2	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Burnham MR (1999), Song JJ (2010), Liu W (2010), Chen TC (2014)	4
EGFR	5	CRKL	1	affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	4
ASB3	0	ARHGAP32	11	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	ARHGAP32	11	affinity chromatography technology	Choudhury NR (2017)	1
SRC	2	BCAR1	6	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Burnham MR (1999), Burnham MR (1999), Wei L (2002), Hsia DA (2003), Kovacic-Milivojevic B (2001), Donaldson JC (2000), Angers-Loustau A (1999), Cabodi S (2004), Modzelewska K (2006), Sawada Y (2006), Riggins RB (2006), Riggins RB (2006)	12
CDH1	4	CRK	0	bioid	Guo Z (2014)	1
CRK	0	GAB1	3	affinity chromatography technology	Brehme M (2009)	1
CDC42	3	CDH1	4	pull down, affinity chromatography technology	Shen Y (2008), Shen Y (2008)	2
EGLN3	0	RAC1	7	affinity chromatography technology	Rodriguez J (2016)	1
GRIN2B	30	FYN	1	pull down, enzymatic study	Takagi N (1999), Wechsler A (1998)	2
PLCG1	6	SYNCRIP	6	pull down	Fu C (1997)	1
NCK2	2	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Chen M (1998), Braverman LE (1999), Tu Y (1998), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	6
SYNCRIP	6	ARHGAP32	11	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	ABI2	4	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	SFN	1	affinity chromatography technology	Urano T (2002)	1
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
NTRK1	1	GAB2	3	affinity chromatography technology	Emdal KB (2015)	1
ARHGAP32	11	EGFR	5	affinity chromatography technology	Nakamura T (2002)	1
ARHGAP32	11	SHC3	1	affinity chromatography technology, pull down	Nakamura T (2002), Nakamura T (2002)	2
GRB2	2	PIK3R1	6	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Saleem A (1995), Saleem A (1995), Wang J (1995), Wang J (1995), Wang J (1995), Bandyopadhyay S (2010), Takahashi Y (1999), Gelkop S (2001), Jain SK (1997), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Cerboni C (1998), Bisson N (2011), Bisson N (2011), Weinger JG (2008), Weinger JG (2008), Weinger JG (2008)	18
ARHGAP32	11	PIK3R1	6	affinity chromatography technology	Moon SY (2003)	1
ABI2	4	EGLN3	0	two hybrid	Rolland T (2014)	1
CDH1	4	CRKL	1	bioid	Guo Z (2014)	1
EGLN3	0	CDC42	3	affinity chromatography technology	Rodriguez J (2016)	1
PTPRK	1	ARHGAP32	11	bioid	St-Denis N (2016)	1
CDH1	4	GAB1	3	bioid	Guo Z (2014)	1
SFN	1	ARHGAP32	11	affinity chromatography technology	Benzinger A (2005)	1
NTRK1	1	SYNCRIP	6	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, imaging technique	Tong J (2009), Wen G (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Chen TC (2014)	6
ATXN1	2	DZIP3	6	two hybrid, affinity chromatography technology, enzymatic study	Lim J (2006), Yoon JH (2013), Yoon JH (2013)	3
GRB2	2	BCAR1	6	affinity chromatography technology, pull down, affinity chromatography technology	Wang X (2000), Angers-Loustau A (1999), Ambrogio C (2005)	3
NTRK1	1	CRKL	1	affinity chromatography technology	Emdal KB (2015)	1
MDFI	1	ARHGAP32	11	two hybrid	Rolland T (2014)	1
NTRK1	1	PLCG1	6	pull down, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Ohmichi M (1991), Qian X (1998), Meakin SO (1999), Koch A (2000), Emdal KB (2015), Emdal KB (2015)	6
EGFR	5	GRB2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schulze WX (2006), Blagoev B (2003), Oneyama C (2002), Wong L (1999), Okutani T (1994), Okutani T (1994), Okutani T (1994), Tortora G (1997), Daly RJ (1996), Buday L (1994), Lowenstein EJ (1992), Lowenstein EJ (1992), Braverman LE (1999), Khan EM (2008), Bonaccorsi L (2007), Miraoui H (2010), Tong J (2009), Severe N (2011), Takahashi Y (1999), Tarcic G (2009), Thien CB (1997), Burke P (2001), Katayama H (1999), Meisner H (1995), Kurada BR (2009), Tong J (2008), Bisson N (2011), Fukazawa T (1996), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Sigismund S (2013), Foerster S (2013), Bisson N (2011), Gotoh N (1994), Wu SL (2006), Wu SL (2006), Tong J (2014), Oksvold MP (2001), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Song F (2016), Song F (2016), Ueno H (1995), Ueno H (1995), Ueno H (1995), Prigent SA (1996), Kapoor GS (2010), Kapoor GS (2010), Okamura T (2009)	51
ARHGAP32	11	GAB1	3	affinity chromatography technology	Zhao C (2003)	1
NTRK1	1	SORT1	1	affinity chromatography technology	Emdal KB (2015)	1
NPHP1	2	ARHGAP32	11	two hybrid, two hybrid	Eley L (2008), Eley L (2008)	2
CDH1	4	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Genda T (2000), Swaminathan G (2011), Shen Y (2008), Guo Z (2014)	4
CRKL	1	GAB1	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Sakkab D (2000), Sakkab D (2000), Chen TC (2014)	3
CDH1	4	LZTS2	4	bioid	Guo Z (2014)	1
CDC42	3	BCAR1	6	affinity chromatography technology	Modzelewska K (2006)	1
NTRK1	1	SHC1	0	two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Qian X (1998), Borrello MG (1994), Nakamura T (2002), Meakin SO (1999), Koch A (2000), Emdal KB (2015), Emdal KB (2015)	7
EGLN3	0	CRKL	1	affinity chromatography technology	Rodriguez J (2016)	1
PTPRK	1	EGFR	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RAC1	7	LZTS2	4	two hybrid	Rolland T (2014)	1
FYN	1	ARHGAP32	11	two hybrid, pull down, affinity chromatography technology	Taniguchi S (2003), Taniguchi S (2003), Taniguchi S (2003)	3
CRK	0	SFN	1	affinity chromatography technology	Brehme M (2009)	1
CRK	0	ARHGAP32	11	pull down, affinity chromatography technology, affinity chromatography technology	Zhao C (2003), Zhao C (2003), Moon SY (2003)	3
RHOA	0	SMURF1	4	pull down, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Asanuma K (2006), Tian M (2011), Tian M (2011), Tian M (2011), Lee MG (2016), He S (2017)	6
SHC3	1	NTRK1	1	affinity chromatography technology, affinity chromatography technology	Nakamura T (1998), Emdal KB (2015)	2
AES	2	ARHGAP32	11	two hybrid	Rolland T (2014)	1
SORT1	1	SYNCRIP	6	affinity chromatography technology	Hein MY (2015)	1
CRKL	1	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, pull down	Gesbert F (1998), Gelkop S (2001), Ren SY (2005)	3
BCAR1	6	NPHP1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology	Donaldson JC (2000), Donaldson JC (2000), Benzing T (2001), Eley L (2008), Eley L (2008), Eley L (2008)	6
EGFR	5	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Schulze WX (2006), Sakaguchi K (1998), Tong J (2009), Crovello CS (1998), Graus-Porta D (1997), Oksvold MP (2001), Burke P (2001), Katayama H (1999), Tong J (2008), Zhang L (1999), Levkowitz G (1999), Fukazawa T (1996), Jones RB (2006), Sigismund S (2013), Foerster S (2013), Gotoh N (1994), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), Li J (2013), Prigent SA (1996), Prigent SA (1996), Grosse R (2000), Yao Z (2017), Wills MK (2014), Wills MK (2014), Kapoor GS (2010)	29
ARHGAP32	11	SHC1	0	affinity chromatography technology	Nakamura T (2002)	1
NCK1	0	PIK3R1	6	affinity chromatography technology	Gelkop S (2001)	1
ARHGAP32	11	LZTS2	4	two hybrid	Rolland T (2014)	1
SFN	1	BCAR1	6	affinity chromatography technology	Benzinger A (2005)	1
ATXN1	2	ARHGAP32	11	two hybrid	Lim J (2006)	1
GAB2	3	ARHGAP32	11	two hybrid, affinity chromatography technology	Zhao C (2003), Zhao C (2003)	2
NCK1	0	GRB2	2	affinity chromatography technology, affinity chromatography technology	de Castro RO (2012), de Castro RO (2012)	2
NTRK1	1	GAB1	3	affinity chromatography technology	Emdal KB (2015)	1
PIK3R1	6	GAB1	3	pull down, affinity chromatography technology, far western blotting, two hybrid, affinity chromatography technology, far western blotting, affinity chromatography technology	Bertagnolo V (1998), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Rocchi S (1998), Ingham RJ (1998), Ingham RJ (1998), Fan YX (2013)	7
NCK2	2	NCK1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ATXN1	2	FYN	1	two hybrid	Lim J (2006)	1
GAB1	3	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting	Ueno E (2001), Ueno E (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996)	4
GRB2	2	SHC1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Blagoev B (2003), Skolnik EY (1993), Skolnik EY (1993), Puil L (1994), Satoh T (1996), Fixman ED (1996), Fixman ED (1996), Fixman ED (1996), Ishihara H (1997), Fournier E (1999), Ravichandran KS (1994), Lamprecht R (2002), Park RK (1999), Sakaguchi K (2001), Park RK (1999), Park RK (1999), Hallak H (2001), Yokote K (1994), Saci A (2002), Zhang S (1999), Lazar DF (1994), VanderKuur J (1995), Kanai M (1997), Spivak-Kroizman T (1994), Giordano V (1997), Drobot L (2005), Erdreich-Epstein A (1997), Takahashi Y (1999), Barber DL (1997), Ahn SC (2003), Odai H (1995), Panchamoorthy G (1996), Panchamoorthy G (1996), Brehme M (2009), Brehme M (2009), Brehme M (2009), Cerboni C (1998), Zhang L (1999), Brizzi MF (1996), Brizzi MF (1996), Liu BA (2012), Bisson N (2011), Fukazawa T (1996), Bisson N (2011), Umehara H (2002), Oksvold MP (2001), Oksvold MP (2001), Li J (2013), Li J (2013), Ueno H (1995), Prigent SA (1996), Wills MK (2014), Rausch O (1997), Ho JM (2002), Ho JM (2002), Yu WM (2006), Klint P (1995)	57
ZWINT	1	ARHGAP32	11	affinity chromatography technology	Hein MY (2015)	1
EGLN3	0	RHOA	0	affinity chromatography technology	Rodriguez J (2016)	1
ARHGAP32	11	GRIN2B	30	affinity chromatography technology, pull down, two hybrid	Nakazawa T (2003), Nakazawa T (2003), Nakazawa T (2003)	3
LZTS2	4	PLCG1	6	affinity chromatography technology	Huttlin EL (2017)	1
CDH1	4	ARHGAP32	11	bioid	Guo Z (2014)	1
FZR1	1	ARHGAP32	11	affinity chromatography technology, affinity chromatography technology	Kannan M (2012), Kannan M (2012)	2
EGFR	5	ARRB1	2	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
EGLN3	0	GRB2	2	affinity chromatography technology	Rodriguez J (2016)	1
CRK	0	GRB2	2	pull down, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Riordan SM (2000), Matsuda M (1996), Okada S (1996), Okada S (1996), Garcia-Guzman M (2000), Brehme M (2009)	6
EGLN3	0	ZWINT	1	affinity chromatography technology	Rodriguez J (2016)	1
SORT1	1	ARHGAP32	11	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	SRC	2	affinity chromatography technology	Emdal KB (2015)	1
NXF1	0	DZIP3	6	affinity chromatography technology	Castello A (2012)	1
HNRNPD	3	SFN	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	He C (2006), He C (2006), He C (2006), He C (2006), He C (2006)	5
NTRK1	1	PIK3R1	6	affinity chromatography technology	Emdal KB (2015)	1
ARHGAP32	11	SMURF1	4	affinity chromatography technology, affinity chromatography technology	Kannan M (2012), Kannan M (2012)	2
ARHGAP32	11	PLCG1	6	affinity chromatography technology	Moon SY (2003)	1
TRIM25	5	FZR1	1	affinity chromatography technology	Choudhury NR (2017)	1
GAB2	3	GAB1	3	two hybrid	van den Akker E (2004)	1
BCAR1	6	FYN	1	two hybrid, affinity chromatography technology, pull down	Donaldson JC (2000), Manie SN (1997), Manie SN (1997)	3
SMURF1	4	SYNCRIP	6	affinity chromatography technology	Xie Y (2013)	1
CDH1	4	NCK1	0	bioid	Guo Z (2014)	1
ARHGAP32	11	RAC1	7	enzymatic study, enzymatic study, enzymatic study	Zhao C (2003), Moon SY (2003), Nakamura T (2002)	3
CRKL	1	SHC1	0	affinity chromatography technology	Chin H (1997)	1
EGFR	5	PLCG1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tvorogov D (2002), Bedrin MS (1997), Crovello CS (1998), Choi JH (2003), Jones RB (2006), Tong J (2014), Egan JE (2002), Wu D (2009), Wu D (2009)	9
TRIM25	5	ABI2	4	affinity chromatography technology	Choudhury NR (2017)	1
GAB2	3	CRKL	1	affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology	Crouin C (2001), Crouin C (2001), Crouin C (2001), Schaeper U (2000)	4
EGFR	5	CRK	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay, affinity chromatography technology	Schulze WX (2006), Hashimoto Y (1998), Hashimoto Y (1998), Katayama H (1999), Ota S (1998), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	9
AES	2	GRB2	2	two hybrid	Rolland T (2014)	1
NXF1	0	ABI2	4	affinity chromatography technology	Castello A (2012)	1
EGLN3	0	LZTS2	4	affinity chromatography technology	Rodriguez J (2016)	1
CDH1	4	EGFR	5	affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, bioid	Pece S (2000), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Li J (2013), Guo Z (2014)	6
NTRK1	1	EGFR	5	affinity chromatography technology	Emdal KB (2015)	1
EGFR	5	SHC2	3	unspecified method, affinity chromatography technology	Jones RB (2006), Wills MK (2014)	2
TRIM25	5	EGLN3	0	affinity chromatography technology	Choudhury NR (2017)	1
SMURF1	4	HNRNPD	3	affinity chromatography technology	Xie Y (2013)	1
SHC1	0	PIK3R1	6	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Harrison-Findik D (1995), Ren SY (2005), Ren SY (2005), Brehme M (2009), Cerboni C (1998), Lee DY (2010)	6
CRK	0	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique	Gelkop S (2001), Gelkop S (2001), Garcia-Guzman M (2000), Brehme M (2009), Grossmann A (2015), Chen TC (2014)	6
NTRK1	1	HNRNPD	3	affinity chromatography technology	Emdal KB (2015)	1
SHC1	0	PLCG1	6	affinity chromatography technology	Fixman ED (1996)	1
ARHGAP32	11	CDC42	3	enzymatic study, enzymatic study, enzymatic study, two hybrid	Nakazawa T (2003), Zhao C (2003), Nakamura T (2002), Bandyopadhyay S (2010)	4
CDC42	3	ARRB1	2	two hybrid	Bandyopadhyay S (2010)	1
GAB2	3	PIK3R1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down	Lynch DK (2002), Crouin C (2001), Crouin C (2001), Schaeper U (2000), Ren SY (2005), Momose H (2003)	6
NCK2	2	ARHGAP32	11	two hybrid	Rolland T (2014)	1
BCAR1	6	NCK1	0	affinity chromatography technology, unspecified method	Okabe S (2002), Liu BA (2012)	2
GRB2	2	HNRNPD	3	affinity chromatography technology	Brehme M (2009)	1
PLCG1	6	GAB2	3	pull down	Zhao C (1999)	1
ARRB1	2	SRC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rosano L (2009), Rosano L (2009), Buchanan FG (2006), Buchanan FG (2006), Lee J (2013)	5
ARRB1	2	ARHGAP32	11	affinity chromatography technology	Xiao K (2007)	1
SHC1	0	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Boudot C (2002), Lynch DK (2002), van den Akker E (2004)	3
HNRNPD	3	SYNCRIP	6	two hybrid, pull down, affinity chromatography technology	Moraes KC (2003), Moraes KC (2003), Hein MY (2015)	3
HNRNPD	3	ARHGAP32	11	affinity chromatography technology	Hein MY (2015)	1
PLCG1	6	SRC	2	affinity chromatography technology	Dhar A (1994)	1
NCK2	2	LZTS2	4	two hybrid	Rolland T (2014)	1
ARHGAP32	11	CRKL	1	pull down, affinity chromatography technology	Nakamura T (2002), Nakamura T (2002)	2
TRIM25	5	GRB2	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	BCAR1	6	affinity chromatography technology	Choudhury NR (2017)	1
DZIP3	6	ARHGAP32	11	two hybrid	Rolland T (2014)	1
GRB2	2	LZTS2	4	two hybrid	Rolland T (2014)	1
NTRK1	1	ARHGAP32	11	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Nakamura T (2002), Nakamura T (2002), Nakamura T (2002), Emdal KB (2015)	4
EGLN3	0	SORT1	1	affinity chromatography technology	Rodriguez J (2016)	1
GAB1	3	SHC1	0	affinity chromatography technology, far western blotting, affinity chromatography technology	Ingham RJ (1998), Ingham RJ (1998), van den Akker E (2004)	3
PTPRK	1	PIK3R1	6	bioid	St-Denis N (2016)	1
SHC1	0	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brehme M (2009), Brehme M (2009), Ota S (1998), Larsson H (1999)	4
SRC	2	GRB2	2	affinity chromatography technology, affinity chromatography technology	Wan KF (2003), Saci A (2002)	2
NCK2	2	ABI2	4	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	4
GRB2	2	ARHGAP32	11	two hybrid	Bandyopadhyay S (2010)	1
BCAR1	6	CRK	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Zhou B (2004), Di Stefano P (2004), Hsia DA (2003), Hsia DA (2003), Gu J (2001), Garton AJ (1999), Angers-Loustau A (1999), Qiu W (1998), Blaukat A (1999), Wang JF (2000), Holcomb M (2006), Wu Y (2005), Cho SY (2000), Modzelewska K (2006), Modzelewska K (2006), Brehme M (2009), Cho SY (2002), Cho SY (2002), Mielenz D (2001), Peterson ME (2008), Liu BA (2012), Larsson H (1999)	22
TRIM25	5	HNRNPD	3	affinity chromatography technology	Choudhury NR (2017)	1
GRB2	2	CDC42	3	two hybrid	Vinayagam A (2011)	1
ATXN1	2	CRK	0	two hybrid, affinity chromatography technology, two hybrid	Lim J (2006), Lim J (2006), Suter B (2013)	3
NCK1	0	EGFR	5	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, two hybrid, protein complementation assay	Tang J (1997), Li W (1992), Braverman LE (1999), Jones RB (2006), Kotlyar M (2015), Petschnigg J (2014)	6
FYN	1	PIK3R1	6	pull down	Kapeller R (1994)	1
PLCG1	6	RHOA	0	affinity chromatography technology, pull down	Thodeti CK (2002), Thodeti CK (2002)	2
EGFR	5	SFN	1	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Wu SL (2006), Wu SL (2006), Kotlyar M (2015), Petschnigg J (2014), Li J (2013)	5
CRK	0	GAB2	3	affinity chromatography technology	Brehme M (2009)	1
EGLN3	0	GAB1	3	affinity chromatography technology	Rodriguez J (2016)	1
FZR1	1	SMURF1	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Kannan M (2012), Kannan M (2012), Wan L (2011), Wan L (2011), Wan L (2011), Wan L (2011)	6
GRB2	2	GAB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Million RP (2004), Lynch DK (2002), Zhao C (1999), Zhao C (1999), Bandyopadhyay S (2010), Brehme M (2009), Bisson N (2011), Rolland T (2014), Huttlin EL (2017), Yu WM (2006), Yu WM (2006)	11
ARHGAP32	11	SHC2	3	affinity chromatography technology	Nakamura T (2002)	1
NTRK1	1	SFN	1	affinity chromatography technology	Emdal KB (2015)	1
NCK1	0	ARHGAP32	11	pull down, affinity chromatography technology	Zhao C (2003), Zhao C (2003)	2
SHC1	0	SHC2	3	affinity chromatography technology	Huttlin EL (2017)	1
PLCG1	6	GRB2	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Pei Z (1997), Pei Z (1997), Nel AE (1995), Scholler JK (2000), Choi JH (2005), Choi JH (2005)	6
BCAR1	6	PIK3R1	6	affinity chromatography technology, pull down	Li E (2000), Li E (2000)	2
FYN	1	CDH1	4	affinity chromatography technology, pull down	Piedra J (2003), Piedra J (2003)	2
NXF1	0	CRKL	1	affinity chromatography technology	Castello A (2012)	1
SHC2	3	GRB2	2	affinity chromatography technology	Wills MK (2014)	1
EGFR	5	GAB1	3	affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, enzymatic study, affinity chromatography technology	Kameda H (2001), Tong J (2008), Kotlyar M (2015), Petschnigg J (2014), Lehr S (1999), Mueller KL (2012)	6
ARHGAP32	11	SRC	2	pull down, affinity chromatography technology	Moon SY (2003), Moon SY (2003)	2
SHC1	0	SRC	2	pull down	Schueller AC (2008)	1
CDH1	4	SFN	1	bioid	Guo Z (2014)	1
GRB2	2	NTRK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Song C (2002), MacDonald JI (2000), Emdal KB (2015), Emdal KB (2015)	4
EGLN3	0	ARHGAP32	11	affinity chromatography technology	Rodriguez J (2016)	1
BCAR1	6	CRKL	1	far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method	Salgia R (1996), Salgia R (1996), Astier A (1997), Peterson ME (2008), Liu BA (2012)	5
NXF1	0	PLCG1	6	affinity chromatography technology	Castello A (2012)	1
SHC3	1	EGFR	5	affinity chromatography technology, unspecified method, pull down	Nakamura T (1998), Jones RB (2006), OBryan JP (1996)	3
GRB2	2	SYNCRIP	6	pull down	Fu C (1997)	1
ARHGAP32	11	ABI2	4	two hybrid	Rolland T (2014)	1
GRB2	2	GAB1	3	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, far western blotting, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Oneyama C (2002), Lewitzky M (2001), Lewitzky M (2001), Lewitzky M (2001), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Holgado-Madruga M (1996), Bandyopadhyay S (2010), Ingham RJ (1998), Brehme M (2009), Fixman ED (1997), Bisson N (2011), Huttlin EL (2017), Kapoor GS (2010), Lehr S (1999)	15
TRIM25	5	SYNCRIP	6	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
EGLN3	0	PTPRK	1	affinity chromatography technology	Rodriguez J (2016)	1
CDH1	4	NCK2	2	bioid	Guo Z (2014)	1
ARHGAP32	11	RHOA	0	enzymatic study, enzymatic study, enzymatic study	Nakazawa T (2003), Nakamura T (2002), Moon SY (2003)	3
CRK	0	SRC	2	affinity chromatography technology, affinity chromatography technology	Hsia DA (2003), Garcia-Guzman M (2000)	2
RAC1	7	GRB2	2	affinity chromatography technology	Huttlin EL (2017)	1
GRB2	2	CRKL	1	affinity chromatography technology	Park RK (1999)	1
BCAR1	6	ARHGAP32	11	pull down, affinity chromatography technology, affinity chromatography technology	Zhao C (2003), Zhao C (2003), Nakamura T (2002)	3
NXF1	0	ARHGAP32	11	affinity chromatography technology	Castello A (2012)	1
NXF1	0	HNRNPD	3	affinity chromatography technology	Castello A (2012)	1