PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CXXC1	3	WDR5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Lee JH (2005), Lee JH (2005), Ansari KI (2008), Butler JS (2008), Mak AB (2010), Kim J (2009), Tang Z (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016)	12
HCFC1	4	OGT	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology	Wysocka J (2003), Wysocka J (2003), Mazars R (2010), Daou S (2011), Capotosti F (2011), Capotosti F (2011), Capotosti F (2011), Havugimana PC (2012), Hauri S (2016)	9
BOD1L1	11	CXXC1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	3
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
CXXC1	3	728505	0	affinity chromatography technology, affinity chromatography technology	Lee JH (2005), Lee JH (2005)	2
BRCA1	7	CAMK2D	3	affinity chromatography technology	Ertych N (2016)	1
HCFC2	1	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
ASH2L	2	DPY30	1	two hybrid, affinity chromatography technology, pull down, two hybrid, two hybrid	Rual JF (2005), Mak AB (2010), Chen Y (2012), Rolland T (2014), Yu H (2011)	5
CAMK2D	3	BOD1L1	11	affinity chromatography technology	Huttlin EL (2017)	1
NUP50	0	CXXC1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CAMK2D	3	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
WDR5	2	SETD1A	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lee JH (2005), Lee JH (2007), Lee JH (2007), Mak AB (2010), Dharmarajan V (2012), Zhang P (2012), Zhang P (2012), Kim J (2013), Tang Z (2013), Huttlin EL (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016), Hauri S (2016)	14
RSBN1	3	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
WDR82	3	DPY30	1	affinity chromatography technology	Tang Z (2013)	1
NUP50	0	SETD1A	12	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EPB41L2	2	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	WDR5	2	affinity chromatography technology	Ertych N (2016)	1
TP53	0	PES1	3	affinity chromatography technology	Li X (2015)	1
HCFC1	4	HCFC2	1	biochemical, affinity chromatography technology	Yokoyama A (2004), Huttlin EL (2017)	2
SETD1B	15	WDR5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007), Dharmarajan V (2012), Zhang P (2012), Zhang P (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016), Hauri S (2016)	12
MDK	0	EPB41L5	0	affinity chromatography technology	Huttlin EL (2017)	1
OGT	4	SETD1A	12	affinity chromatography technology	Hauri S (2016)	1
OGT	4	WDR5	2	affinity chromatography technology, affinity chromatography technology	Hauri S (2016), Hauri S (2016)	2
SETD1B	15	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007), Lee JH (2010), Hein MY (2015), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016)	7
SETD1A	12	SMARCA1	2	affinity chromatography technology	Li X (2011)	1
EP300	36	5430	0	affinity chromatography technology, affinity chromatography technology	Cho H (1998), Fousteri M (2006)	2
EP300	36	HIST2H3C	0	enzymatic study	Cereseto A (2005)	1
CXXC1	3	HIST2H3C	0	affinity chromatography technology	Ansari KI (2008)	1
USF1	0	SETD1A	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011), Li X (2011)	3
ASH2L	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013), Tang Z (2013)	3
HCFC2	1	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
PRPS1	0	BOD1L1	11	affinity chromatography technology	Huttlin EL (2015)	1
SETD1A	12	SETD1B	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007)	3
WDR82	3	WDR5	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Lee JH (2010), Tang Z (2013), Hauri S (2016)	4
TP53	0	SETD1A	12	affinity chromatography technology, affinity chromatography technology, pull down	Tang Z (2013), Tang Z (2013), Tang Z (2013)	3
SETD1B	15	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lee JH (2008), Mak AB (2010), Hein MY (2015), Li Y (2016), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016)	6
CREBBP	29	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Senyuk V (2005), Perissi V (1999), Pasheva E (2004), Shen WF (2001), Kouskouti A (2005), Kouskouti A (2005), Yasuda J (2004), Tropberger P (2013), Das C (2009)	9
BOD1L1	11	SETD1A	12	affinity chromatography technology	Hein MY (2015)	1
EDA	0	SETD1A	12	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
EPB41L5	0	BOD1L1	11	affinity chromatography technology	Huttlin EL (2017)	1
WDR5	2	BOD1L1	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	3
TP53	0	RBBP5	3	pull down, affinity chromatography technology, pull down, genetic interference	Dou Y (2005), Tang Z (2013), Tang Z (2013), Xie L (2013)	4
CREBBP	29	WDR5	2	affinity chromatography technology	Koues OI (2009)	1
MDK	0	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
PES1	3	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
ASH2L	2	HCFC2	1	pull down, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Mak AB (2010), Huttlin EL (2017)	3
TP53	0	ASH2L	2	affinity chromatography technology, pull down	Tang Z (2013), Tang Z (2013)	2
HCFC2	1	OGT	4	affinity chromatography technology	Huttlin EL (2017)	1
ASH2L	2	HIST1H3A	3	enzymatic study	Pavri R (2006)	1
RSBN1	3	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
PES1	3	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
WDR5	2	DPY30	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Bailey JK (2015), Hauri S (2016)	3
SETD1A	12	CREBBP	29	pull down, pull down, affinity chromatography technology	Karetsou Z (2005), Karetsou Z (2005), Karetsou Z (2005)	3
CXXC1	3	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Lee JH (2005), Lee JH (2005), Lee JH (2005), Ansari KI (2008), Butler JS (2008), Mak AB (2010), Kim J (2009), Tang Z (2013), Tang Z (2013), Hein MY (2015), Huttlin EL (2017)	12
PRPS1	0	SETD1A	12	affinity chromatography technology	Huttlin EL (2015)	1
USF1	0	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011), Li X (2011)	3
CAMK2D	3	OGT	4	affinity chromatography technology	Huttlin EL (2017)	1
PRMT2	3	SETD1A	12	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MDK	0	BOD1L1	11	affinity chromatography technology	Huttlin EL (2017)	1
EPB41L5	0	SETD1A	12	affinity chromatography technology	Huttlin EL (2017)	1
CTDSP2	1	5430	0	enzymatic study	Yeo M (2003)	1
CXXC1	3	SETD1B	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Butler JS (2008), Lee JH (2007), Lee JH (2007), Lee JH (2007), Havugimana PC (2012), Tang Z (2013), Hein MY (2015), Hein MY (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016)	11
EDA	0	CXXC1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WDR82	3	5430	0	affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Lee JH (2010)	2
PRMT2	3	CXXC1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ZNF207	2	DPY30	1	affinity chromatography technology	Blomen VA (2015)	1
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
HIST1H3A	3	WDR5	2	affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Higa LA (2006), Schuetz A (2006), Couture JF (2006), Ruthenburg AJ (2006), Han Z (2006), Wysocka J (2005), Wysocka J (2005), Wysocka J (2005), Wysocka J (2005), Bailey JK (2015)	11
CXXC1	3	HCFC1	4	affinity chromatography technology, affinity chromatography technology	Tang Z (2013), Hein MY (2015)	2
CXXC1	3	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013), Tang Z (2013)	3
SETD1A	12	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Lee JH (2005), Lee JH (2008), Mak AB (2010), Li X (2011), Havugimana PC (2012), Kim J (2013), Tang Z (2013), Tang Z (2013), Li Y (2016), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016)	11
BRCA1	7	ASH2L	2	two hybrid, affinity chromatography technology	Woods NT (2012), Ertych N (2016)	2
EP300	36	SETD1A	12	pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013)	2
TP53	0	WDR82	3	pull down	Tang Z (2013)	1
EPB41L3	5	SETD1A	12	affinity chromatography technology	Hauri S (2013)	1
CXXC1	3	WDR82	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Butler JS (2008), Lee JH (2010), Lee JH (2010), Kim J (2009), Tang Z (2013), Tang Z (2013)	7
ZNF207	2	SETD1A	12	affinity chromatography technology	Blomen VA (2015)	1
OGT	4	ASH2L	2	affinity chromatography technology	Hauri S (2016)	1
SETD1B	15	DPY30	1	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	HIST2H3C	0	imaging technique	Ganesan S (2002)	1
EP300	36	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study	Liu B (2009), Brackertz M (2006), Faiola F (2005), Daujat S (2002), Kalkhoven E (2002), Seo SB (2002), Kim JH (2005), Bordoli L (2001), Kim MY (2001), Kutney SN (2004), Wang F (2010), Loven MA (2004), Kiernan RE (1999), Wong K (2005), Ogryzko VV (1996), Yamaguchi Y (2004), Furumatsu T (2005), An W (2002), Delvecchio M (2013), Delvecchio M (2013), Tropberger P (2013), Das C (2009), Shimura M (2011), Ji A (2003), Fu M (2005), Suganuma T (2002), Tang Z (2013), Kim JH (2006), Lopes da Rosa J (2013), Li X (2014), Wang YL (2008), Du C (2017), Yi P (2017), Wan W (2017)	34
RBBP5	3	DPY30	1	affinity chromatography technology	Mak AB (2010)	1
CREBBP	29	TP53	0	enzymatic study, pull down, genetic interference, pull down, enzymatic study, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, x-ray crystallography, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Ito A (2002), Livengood JA (2002), Livengood JA (2002), Giebler HA (2000), Tang Y (2008), Jenkins LM (2009), Shi D (2009), Zhao Y (2006), Saifudeen Z (2005), Scolnick DM (1997), Scolnick DM (1997), Gu W (1997), Gu W (1997), Matsuda S (2004), Pasqualucci L (2011), Lee SK (1999), Dai C (2011), Lee CW (2010), Ferreon JC (2009), Ruas JL (2010), Ruas JL (2010), Huang WC (2007), Huang WC (2007), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Col E (2002), Jansma AL (2014), Jansma AL (2014), Krois AS (2016), Hasegawa K (2008), Huang X (2013), Huang X (2013), Piskacek M (2016)	35
728505	0	SETD1A	12	affinity chromatography technology	Lee JH (2005)	1
BOD1L1	11	RBBP5	3	affinity chromatography technology	Hein MY (2015)	1
PRPS1	0	CXXC1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HCFC1	4	RBBP5	3	biochemical, affinity chromatography technology, biochemical	Yokoyama A (2004), Mak AB (2010), Havugimana PC (2012)	3
CXXC1	3	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Tang Z (2013), Tang Z (2013), Tang Z (2013)	3
PRMT2	3	SETD1B	15	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CAMK2D	3	HCFC1	4	affinity chromatography technology	Huttlin EL (2017)	1
HCFC2	1	BOD1L1	11	affinity chromatography technology	Huttlin EL (2017)	1
728505	0	ASH2L	2	affinity chromatography technology	Lee JH (2005)	1
RBBP5	3	WDR5	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Lee JH (2005), Higa LA (2006), Wysocka J (2005), Wysocka J (2005), Patel SR (2007), Cho YW (2007), Avdic V (2011), Avdic V (2011), Avdic V (2011), Mo R (2006), Gan Q (2011), Mak AB (2010), Mak AB (2010), Wu MZ (2011), Huttlin EL (2015), Bailey JK (2015), Huttlin EL (2017), Carugo A (2016), Hauri S (2016)	20
EPB41L3	5	DPY30	1	affinity chromatography technology	Hauri S (2013)	1
SETD1A	12	HIST2H3C	0	enzymatic study	Zhang P (2012)	1
ASH2L	2	RBBP5	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, pull down	Yokoyama A (2004), Lee JH (2005), Lee JH (2005), Garapaty S (2009), Wysocka J (2005), Patel SR (2007), Patel SR (2007), Cho YW (2007), Cho YW (2007), Butler JS (2011), Avdic V (2011), Mo R (2006), Mo R (2006), Cao F (2010), Cao F (2010), Mak AB (2010), Mak AB (2010), Rolland T (2014), Tang Z (2013), Yu H (2011), Li Y (2016)	21
BRCA1	7	DPY30	1	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	RBBP5	3	affinity chromatography technology	Ertych N (2016)	1
CREBBP	29	5430	0	biochemical, affinity chromatography technology	Cho H (1998), Cho H (1998)	2
EPB41L3	5	EPB41L2	2	affinity chromatography technology, affinity chromatography technology	Hauri S (2013), Huttlin EL (2017)	2
SETD1B	15	5430	0	affinity chromatography technology	Lee JH (2008)	1
SETD1A	12	PNISR	1	biochemical	Wan C (2015)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
CREBBP	29	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Pao GM (2000), Pao GM (2000), Benezra M (2003), Fan S (2002), Fan S (2002), Neish AS (1998), Nakuci E (2006), Crowe DL (2006), Chai YL (1999)	9
USF1	0	HCFC1	4	affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011)	2
ASH2L	2	WDR5	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Lee JH (2005), Wysocka J (2005), McKinnell IW (2008), McKinnell IW (2008), Patel SR (2007), Butler JS (2011), Mo R (2006), Gan Q (2011), Gan Q (2011), Mak AB (2010), Mak AB (2010), Wu MZ (2011), Havugimana PC (2012), Tang Z (2013), Huttlin EL (2015), Bailey JK (2015), Huttlin EL (2017), Hauri S (2016)	19
OGT	4	RBBP5	3	affinity chromatography technology	Hauri S (2016)	1
EP300	36	WDR82	3	pull down, affinity chromatography technology	Tang Z (2013), Tang Z (2013)	2
EPB41L5	0	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
DPY30	1	HCFC1	4	biochemical	Havugimana PC (2012)	1
BRCA1	7	SETD1A	12	affinity chromatography technology	Ertych N (2016)	1
EP300	36	WDR5	2	affinity chromatography technology	Tang Z (2013)	1
728505	0	RBBP5	3	affinity chromatography technology	Lee JH (2005)	1
SETD1A	12	WDR82	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2008), Lee JH (2008), Lee JH (2010), Lee JH (2010), Lee JH (2010), Tang Z (2013), Tang Z (2013), Alicea-Velazquez NL (2016)	10
CXXC1	3	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tate CM (2009), Lee JH (2005), Lee JH (2005), Lee JH (2005), Ansari KI (2008), Butler JS (2008), Mak AB (2010), Kim J (2009), Tang Z (2013), Hein MY (2015), Huttlin EL (2017)	11
ASH2L	2	HCFC1	4	pull down, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Mak AB (2010), Tang Z (2013)	3
CTDSP2	1	SETD1A	12	affinity chromatography technology	Huttlin EL (2015)	1
SETD1A	12	DPY30	1	pull down, affinity chromatography technology	Kim J (2013), Tang Z (2013)	2
LBP	2	SETD1A	12	two hybrid	Wang J (2011)	1
NUP50	0	BOD1L1	11	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
WDR82	3	SETD1B	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee JH (2007), Lee JH (2010), Lee JH (2010), Lee JH (2010), Tang Z (2013), Alicea-Velazquez NL (2016)	6
HIST1H3A	3	SMARCA1	2	affinity chromatography technology	Wysocka J (2006)	1
CXXC1	3	DPY30	1	affinity chromatography technology, affinity chromatography technology	Tang Z (2013), Hein MY (2015)	2
SETD1A	12	RBBP5	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2005), Lee JH (2007), Lee JH (2007), Lee JH (2008), Lee JH (2010), Mersman DP (2012), Mak AB (2010), Li X (2011), Havugimana PC (2012), Kim J (2013), Tang Z (2013), Alicea-Velazquez NL (2016), Alicea-Velazquez NL (2016)	13
TP53	0	WDR5	2	pull down, pull down	Dou Y (2005), Tang Z (2013)	2
EPB41L5	0	ASH2L	2	affinity chromatography technology	Huttlin EL (2017)	1
RBBP5	3	HIST2H3C	0	pull down	Goo YH (2003)	1
WDR82	3	RBBP5	3	affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Tang Z (2013)	2
USF1	0	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011), Li X (2011)	3
CXXC1	3	SETD1A	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ansari KI (2008), Ansari KI (2008), Tate CM (2009), Lee JH (2005), Lee JH (2005), Lee JH (2005), Butler JS (2008), Lee JH (2007), Lee JH (2007), Tate CM (2010), Lee JH (2008), Kim J (2009), Kim J (2013), Tang Z (2013), Tang Z (2013), Hein MY (2015), Huttlin EL (2017), Alicea-Velazquez NL (2016)	18
HCFC1	4	SETD1A	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wysocka J (2003), Lee JH (2008), Alicea-Velazquez NL (2016)	3
EP300	36	RBBP5	3	affinity chromatography technology	Tang Z (2013)	1
USF1	0	WDR5	2	affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011)	2
USF1	0	SMARCA1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang S (2007), Li X (2011), Li X (2011)	3
BRCA1	7	OGT	4	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	HCFC1	4	affinity chromatography technology	Ertych N (2016)	1
OGT	4	CXXC1	3	affinity chromatography technology	Hauri S (2016)	1
SETD1B	15	HIST1H3A	3	enzymatic study	Tang Z (2013)	1
UVSSA	5	SETD1A	12	affinity chromatography technology	Fei J (2012)	1
CAMK2D	3	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
MDK	0	CXXC1	3	affinity chromatography technology	Huttlin EL (2017)	1
SETD1B	15	HIST2H3C	0	enzymatic study	Zhang P (2012)	1
SETD1A	12	5430	0	affinity chromatography technology	Lee JH (2008)	1
HCFC2	1	RBBP5	3	biochemical, affinity chromatography technology	Yokoyama A (2004), Huttlin EL (2017)	2
SETD1A	12	HIST1H3A	3	enzymatic study, enzymatic study, enzymatic study	Kim J (2009), Kim J (2013), Tang Z (2013)	3
HCFC2	1	WDR5	2	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yokoyama A (2004), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	4
HCFC1	4	WDR5	2	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Yokoyama A (2004), Wysocka J (2003), Mak AB (2010), Havugimana PC (2012), Hauri S (2016)	5
WDR82	3	ASH2L	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Lee JH (2010), Tang Z (2013), Tang Z (2013)	4
USF1	0	EP300	36	affinity chromatography technology	Crusselle-Davis VJ (2007)	1
WDR82	3	HCFC1	4	affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Lee JH (2010)	2