PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
ELOC	0	ELOB	1	two hybrid, pull down, pull down, pull down, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, two hybrid, affinity chromatography technology, x-ray crystallography, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, pull down, two hybrid, biochemical, biochemical, two hybrid	Rual JF (2005), Ohh M (1999), Aso T (1995), Li Z (2002), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Kinoshita K (2007), Lievens S (2009), Brower CS (1999), Stebbins CE (1999), Pause A (1999), Pause A (1999), Havugimana PC (2012), Wang X (2013), Kristensen AR (2012), Costessi A (2011), Rolland T (2014), Kim DY (2013), Wan C (2015), Yu H (2011)	21
CUL3	17	CUL1	7	affinity chromatography technology, affinity chromatography technology, biochemical	Bennett EJ (2010), Bennett EJ (2010), Wan C (2015)	3
VCP	6	UBE2M	0	affinity chromatography technology	Yu CC (2013)	1
UBE2D3	1	MKRN3	2	two hybrid	Markson G (2009)	1
CUL5	1	ELOC	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology	Kamura T (2001), Nishiya T (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Kershaw NJ (2014), Huttlin EL (2017)	18
UBE2D2	0	UBE2F	1	biochemical	Wan C (2015)	1
SPSB1	3	CUL5	1	affinity chromatography technology	Kamura T (2004)	1
CDC34	3	CUL3	17	pull down	Plafker KS (2009)	1
ELOC	0	SPSB1	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Nishiya T (2011), Lievens S (2009), Kamura T (2004)	3
ELOC	0	GHR	1	unspecified method	Bulatov E (2015)	1
SPSB2	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kamura T (2004), Huttlin EL (2015), Huttlin EL (2017)	3
UBE2Q1	0	RNF7	0	two hybrid	Markson G (2009)	1
SPSB1	3	RNF7	0	affinity chromatography technology	Kamura T (2004)	1
CUL4A	2	GLMN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tron AE (2012), Tron AE (2012), Huttlin EL (2017)	3
SPSB2	0	ELOB	1	affinity chromatography technology	Kamura T (2004)	1
BTRC	1	UBE2D1	0	affinity chromatography technology	Fernandez-Sanchez ME (2010)	1
UBE2D1	0	CHFR	5	two hybrid, pull down, pull down, pull down	Markson G (2009), Kim JM (2010), Kang D (2002), Jung I (2012)	4
DCUN1D4	0	CUL4B	8	pull down, enzymatic study	Monda JK (2013), Monda JK (2013)	2
CSNK2A1	15	UBE2D3	1	enzymatic study	Gao Z (2014)	1
CDC34	3	CUL2	3	pull down	Sandoval D (2014)	1
RNF7	0	RNF7	0	pull down	Swaroop M (1999)	1
RNF7	0	GLMN	2	pull down	Tron AE (2012)	1
ASB7	1	RNF7	0	affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Andresen CA (2014)	2
BTRC	1	UBE2D3	1	pull down	Chong RA (2014)	1
IKBKG	0	RNF7	0	pull down, affinity chromatography technology, two hybrid	Fenner BJ (2010), Fenner BJ (2010), Fenner BJ (2010)	3
VCP	6	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li JM (2013), Riemer A (2014), Zhang Z (2015)	3
ASB4	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ferguson JE (2007), Andresen CA (2014), Andresen CA (2014)	3
UBE2D1	0	RNF7	0	two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Markson G (2009), Yasukawa T (2008), Zakaria R (2013), Kuang Z (2010), Lamsoul I (2011), Heuze ML (2008), Kershaw NJ (2014), Uematsu K (2016), Lo JY (2017)	9
DCUN1D2	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
SKP2	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Bennett EJ (2010)	2
DCUN1D3	1	CUL3	17	pull down, affinity chromatography technology, pull down, imaging technique, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	11
DCUN1D2	0	CUL5	1	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
CUL4A	2	BTRC	1	affinity chromatography technology	He YJ (2006)	1
RNF7	0	CSNK2A1	15	affinity chromatography technology, enzymatic study, enzymatic study	Kim YS (2002), Son MY (1999), Kim YS (2002)	3
ASB2	1	DCUN1D3	1	affinity chromatography technology	Huttlin EL (2017)	1
NEDD4L	3	CDC34	3	pull down	Sheng Y (2012)	1
CUL1	7	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Suzuki H (2000), Cenciarelli C (1999), Sowa ME (2009), Megumi Y (2005), Davis M (2002), Kawakami T (2001), Read MA (2000), Suzuki H (1999), Kumar KG (2007), Schweitzer K (2007), Chua YS (2011), Winston JT (1999), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Latres E (1999), Yoshida Y (2007), Bennett EJ (2010), Cui W (2012), Dehan E (2009), Busino L (2003), Chung FZ (2014), Chen ZW (2015), Kim TY (2014), Read MA (2000), Coyaud E (2015), Low TY (2014), Coyaud E (2015), He N (2005), Huttlin EL (2017), Kuang P (2016), Reitsma JM (2017), Reitsma JM (2017)	34
CUL4A	2	CUL3	17	affinity chromatography technology	Bennett EJ (2010)	1
MNAT1	0	RNF7	0	two hybrid	Woodsmith J (2012)	1
DCUN1D5	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
UBE2S	2	VHL	0	pull down, pull down, enzymatic study, affinity chromatography technology	Lim JH (2016), Lim JH (2016), Lim JH (2016), Lim JH (2016)	4
SOCS3	0	RNF7	0	affinity chromatography technology, pull down	Kamura T (2004), Kershaw NJ (2014)	2
ASB1	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Mahrour N (2008), Bennett EJ (2010), Andresen CA (2014), Huttlin EL (2017)	5
UBE2F	1	CUL1	7	enzymatic study	Siergiejuk E (2009)	1
UBE2D3	1	CHFR	5	two hybrid, pull down, pull down	Markson G (2009), Chaturvedi P (2002), Liu C (2013)	3
MKRN3	2	RNF7	0	two hybrid	Woodsmith J (2012)	1
DCUN1D5	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
ASB6	1	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Bennett EJ (2010), Andresen CA (2014), Huttlin EL (2017)	4
CBFB	1	ELOB	1	biochemical	Kim DY (2013)	1
ELOC	0	ASB6	1	two hybrid, affinity chromatography technology	Lievens S (2009), Huttlin EL (2017)	2
ASB7	1	ELOC	0	affinity chromatography technology	Andresen CA (2014)	1
CUL4A	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
CDC34	3	BTRC	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, bioid, affinity chromatography technology	Semplici F (2002), Cenciarelli C (1999), Sowa ME (2009), Fernandez-Sanchez ME (2010), Chong RA (2014), Burrows AC (2012), Coyaud E (2015), Huttlin EL (2017)	8
CUL5	1	ELOB	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down	Kamura T (2001), Nie L (2011), Wolfe LS (2010), Yu X (2003), Xiao Z (2006), Zhou X (2012), Luo K (2007), Yu Y (2004), Bennett EJ (2010), Salter JD (2012), Muniz JR (2013), Kelsall IR (2013), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014), Antonioli M (2014), Kershaw NJ (2014)	18
SKP2	2	DCUN1D3	1	affinity chromatography technology	Zhang S (2016)	1
ASB13	0	RNF7	0	affinity chromatography technology	Andresen CA (2014)	1
CUL2	3	GLMN	2	affinity chromatography technology, affinity chromatography technology	Tron AE (2012), Huttlin EL (2017)	2
VCP	6	UBE2S	2	affinity chromatography technology	Yu CC (2013)	1
DCUN1D3	1	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
UBE2D2	0	RNF7	0	two hybrid, pull down	Markson G (2009), Kershaw NJ (2014)	2
SOCS3	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, pull down	Xiao Z (2007), Kamura T (2004), Kershaw NJ (2014)	3
CUL3	17	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Schenkova K (2012)	3
ASB2	1	RNF7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Bello NF (2009), Zakaria R (2013)	3
CUL3	17	GLMN	2	affinity chromatography technology	Tron AE (2012)	1
CSNK2A1	15	VHL	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Lolkema MP (2005), Lolkema MP (2005), Yang H (2007)	3
CSNK2B	5	RNF7	0	two hybrid, pull down, affinity chromatography technology, two hybrid	Ahn BH (2001), Ahn BH (2001), Kim YS (2002), Son MY (1999)	4
DCUN1D2	0	ELOB	1	affinity chromatography technology	Keuss MJ (2016)	1
UBE2M	0	CUL3	17	enzymatic study, pull down	Huang G (2011), Schumacher FR (2015)	2
SPSB2	0	RNF7	0	affinity chromatography technology	Kamura T (2004)	1
RNF7	0	CBFB	1	pull down	Kim DY (2013)	1
CUL3	17	VCP	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Besten Wd (2012)	2
DCUN1D4	0	CUL1	7	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
RNF7	0	SKP2	2	affinity chromatography technology, affinity chromatography technology	Duan H (2001), Duan H (2001)	2
RNF7	0	ERBIN	5	enzymatic study	Kuang P (2016)	1
VHL	0	ELOB	1	affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Ohh M (1999), Min JH (2002), Hacker KE (2008), Menon S (2008), Kamura T (2002), Kamura T (2002), Kuznetsova AV (2003), Cockman ME (2000), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Kinoshita K (2007), Lai Y (2012), Mahrour N (2008), Mahrour N (2008), Grosfeld A (2007), Foxler DE (2012), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017)	43
CUL1	7	GLMN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Tron AE (2012), Tron AE (2012), Duda DM (2012), Tron AE (2012), Huttlin EL (2017)	5
RNF7	0	GHR	1	unspecified method	Bulatov E (2015)	1
RAB40C	0	ELOC	0	affinity chromatography technology	Kamura T (2004)	1
SOCS3	0	ELOC	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Xiao Z (2007), Zhang WN (2012), Haan S (2003), Haan S (2003), Kamura T (2004)	5
UBE2D3	1	UBE2C	1	biochemical	Wan C (2015)	1
UBE2D2	0	UBE2M	0	biochemical	Havugimana PC (2012)	1
CUL4A	2	SKP2	2	affinity chromatography technology	Bondar T (2006)	1
CUL4B	8	UBE2D3	1	pull down	Li X (2011)	1
UBE2D1	0	TRIM8	6	two hybrid	Markson G (2009)	1
ELOB	1	GHR	1	unspecified method	Bulatov E (2015)	1
CUL2	3	UBE2D1	0	pull down, affinity chromatography technology, pull down	Sufan RI (2006), Sufan RI (2006), Maine GN (2007)	3
ASB10	3	RNF7	0	affinity chromatography technology	Andresen CA (2014)	1
SPSB1	3	ELOB	1	affinity chromatography technology	Kamura T (2004)	1
ASB2	1	UBE2D1	0	pull down	Bello NF (2009)	1
MNAT1	0	MKRN3	2	two hybrid	Woodsmith J (2012)	1
SOCS3	0	ELOB	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xiao Z (2007), Niwa Y (2005), Kamura T (2004)	3
ASB12	0	CUL5	1	affinity chromatography technology	Kohroki J (2005)	1
CUL3	17	CUL2	3	biochemical	Wan C (2015)	1
SOCS2	1	ELOC	0	affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical	Vesterlund M (2011), Lievens S (2009), Lievens S (2009), Kim DY (2013)	4
DCUN1D3	1	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
VHL	0	ELOC	0	affinity chromatography technology, pull down, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Tsuchiya H (1996), Min JH (2002), Li Z (2002), Hacker KE (2008), Kim BY (2008), Baek JH (2007), Baek JH (2007), Kuznetsova AV (2003), Cockman ME (2000), Lisztwan J (1999), Stickle NH (2004), Lai Y (2011), Liu YV (2007), Norman JA (2006), Kinoshita K (2007), Cai Q (2010), Lai Y (2012), Miller F (2005), Mahrour N (2008), Mahrour N (2008), Russell RC (2011), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Stebbins CE (1999), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	48
NEDD4L	3	UBE2D1	0	pull down, pull down, pull down, pull down	Schwarz SE (1998), Herhaus L (2013), Bosanac I (2011), Todaro DR (2017)	4
ASB6	1	ELOB	1	affinity chromatography technology, affinity chromatography technology	Andresen CA (2014), Huttlin EL (2017)	2
ASB10	3	ELOB	1	affinity chromatography technology	Andresen CA (2014)	1
CSNK2B	5	BTRC	1	affinity chromatography technology	Tsuchiya Y (2010)	1
ASB12	0	RNF7	0	affinity chromatography technology	Kohroki J (2005)	1
ASB10	3	CUL5	1	affinity chromatography technology	Andresen CA (2014)	1
RNF7	0	CUL3	17	enzymatic study	Huang DT (2009)	1
DCUN1D4	0	CUL2	3	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
VCP	6	CSNK2B	5	affinity chromatography technology	Yu CC (2013)	1
ASB2	1	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Nie L (2011), Nie L (2011), Bello NF (2009), Zakaria R (2013), Huttlin EL (2017)	6
ASB10	3	ELOC	0	affinity chromatography technology	Andresen CA (2014)	1
CUL2	3	UBE2M	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
CDC34	3	UBE2D3	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
UBE2D4	0	TRIM8	6	two hybrid	Markson G (2009)	1
TRIM8	6	RNF7	0	two hybrid	Woodsmith J (2012)	1
CUL5	1	GHR	1	unspecified method	Bulatov E (2015)	1
DCUN1D4	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
DCUN1D5	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
ASB1	2	RNF7	0	affinity chromatography technology	Kohroki J (2005)	1
UBE2S	2	UBE2D3	1	affinity chromatography technology	Kuang P (2016)	1
CSNK2A1	15	CSNK2B	5	pull down, affinity chromatography technology, far western blotting, two hybrid, two hybrid, two hybrid, pull down, enzymatic study, affinity chromatography technology, two hybrid, enzymatic study, biochemical, far western blotting, far western blotting, x-ray crystallography, enzymatic study, two hybrid, affinity chromatography technology, two hybrid, biochemical, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Kim MS (1998), Kim MS (1998), Marin O (1997), Bosc DG (2000), Ahn BH (2001), Kusk M (1999), Benitez MJ (2001), Uhle S (2003), Olsen BB (2008), Son MY (1999), Son MY (1999), Havugimana PC (2012), Llorens F (2003), Llorens F (2003), Niefind K (2001), Lee NY (2009), Wang J (2011), So J (2015), Wallach T (2013), Wan C (2015), Gao Z (2014), Ren K (2011), Goetz C (1999), Hauri S (2016)	24
GEM	1	RNF7	0	two hybrid	Wang J (2008)	1
DCUN1D3	1	CUL1	7	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Huang G (2014), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	8
UBE2M	0	DCUN1D3	1	pull down, pull down, pull down	Monda JK (2013), Meyer-Schaller N (2009), Keuss MJ (2016)	3
UBE2F	1	DCUN1D2	0	pull down	Monda JK (2013)	1
CUL2	3	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
UBE2D2	0	TRIM8	6	two hybrid, pull down	Markson G (2009), Li Q (2011)	2
CUL4A	2	VCP	6	affinity chromatography technology	Besten Wd (2012)	1
UBE2D2	0	MKRN3	2	two hybrid	Markson G (2009)	1
CUL5	1	CUL1	7	affinity chromatography technology	Bennett EJ (2010)	1
TRIM8	6	MKRN3	2	two hybrid	Woodsmith J (2012)	1
SKP2	2	CDC34	3	pull down, enzymatic study, pull down	Cen B (2010), Umanskaya K (2007), Ji P (2006)	3
ASB1	2	ELOB	1	affinity chromatography technology, affinity chromatography technology	Mahrour N (2008), Andresen CA (2014)	2
DCUN1D4	0	CUL3	17	pull down, enzymatic study, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	5
UBE2M	0	CUL1	7	enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study	Huang G (2011), Huang G (2011), Kim AY (2008), Ponyeam W (2012), Ohki Y (2009), Zhou W (2017), Mo Z (2016)	7
SOCS3	0	SOCS2	1	affinity chromatography technology	Tannahill GM (2005)	1
VHL	0	UBE2D2	0	pull down	Xin H (2011)	1
CDC34	3	CSNK2B	5	pull down, affinity chromatography technology, enzymatic study	Block K (2001), Block K (2001), Block K (2001)	3
DCUN1D5	0	UBE2F	1	pull down	Monda JK (2013)	1
SOCS2	1	RNF7	0	affinity chromatography technology	Vesterlund M (2011)	1
VCP	6	CUL2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bennett EJ (2010), Besten Wd (2012)	3
UBE2M	0	CUL5	1	enzymatic study	Duda DM (2008)	1
ASB12	0	ELOC	0	affinity chromatography technology	Andresen CA (2014)	1
CBFB	1	ELOC	0	biochemical	Kim DY (2013)	1
NEDD4	2	UBE2D1	0	pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Vina-Vilaseca A (2010), Sehat B (2008), Platta HW (2012), Tofaris GK (2011), Uchiki T (2009), Liu PY (2012), Sugeno N (2014), Kim HT (2007), Chen Z (2016)	9
UBE2D2	0	BTRC	1	enzymatic study	Cenciarelli C (1999)	1
UBE2D2	0	CHFR	5	two hybrid, pull down, pull down, pull down	Markson G (2009), Kang D (2002), Oh YM (2009), Chaturvedi P (2002)	4
ASB6	1	RNF7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Andresen CA (2014), Huttlin EL (2017)	3
ELOB	1	ASB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011), Bello NF (2009), Zakaria R (2013)	4
DCUN1D5	0	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
DCUN1D4	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
UBE2D2	0	NEDD4L	3	x-ray crystallography, pull down, pull down, pull down, pull down, pull down, enzymatic study	Kamadurai HB (2009), Isasa M (2010), Sheng Y (2012), Persaud A (2009), Nazio F (2016), Todaro DR (2017), Todaro DR (2017)	7
RNF7	0	VHL	0	affinity chromatography technology	Tan M (2008)	1
DCUN1D3	1	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
SOCS2	1	CUL5	1	affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology	Vesterlund M (2011), Bennett EJ (2010), Salter JD (2012), Kim YK (2013), Huttlin EL (2017)	5
DCUN1D3	1	CUL4B	8	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
GHR	1	SOCS2	1	pull down, enzymatic study, pull down, unspecified method, unspecified method	Ram PA (1999), Vesterlund M (2011), Biener E (2002), Bulatov E (2015), Bullock AN (2006)	5
VHL	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Kamura T (2001), Hacker KE (2008), Hacker KE (2008), Menon S (2008), Chew EH (2007), Ietta F (2006), Megumi Y (2005), Kamura T (2002), Kuznetsova AV (2003), Hansen WJ (2002), Cockman ME (2000), Lisztwan J (1999), Lisztwan J (1999), Sufan RI (2006), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Knauth K (2006), Lonergan KM (1998), Lai Y (2012), Miller F (2005), Mahrour N (2008), Grosfeld A (2007), Russell RC (2011), Foxler DE (2012), Bonicalzi ME (2001), Bennett EJ (2010), Kanaya K (2002), Liakopoulos D (1999), Pause A (1997), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Pause A (1999), Pause A (1999), Xin H (2011), Kamura T (2004), Kamura T (2004), Heir P (2013), Russell RC (2008), Russell RC (2008), Essers PB (2014), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Heir P (2016), Chen K (2016), Uematsu K (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	54
ASB13	0	ELOB	1	affinity chromatography technology	Andresen CA (2014)	1
IKBKG	0	CUL1	7	affinity chromatography technology	Orel L (2010)	1
DCUN1D5	0	CUL4B	8	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
ASB4	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Andresen CA (2014), Andresen CA (2014)	2
CUL2	3	SKP2	2	affinity chromatography technology	Kimura Y (2007)	1
DCUN1D3	1	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
VCP	6	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Zhang Z (2015)	3
RAB40C	0	ELOB	1	affinity chromatography technology	Kamura T (2004)	1
DCUN1D5	0	CUL3	17	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	7
CUL3	17	ELOC	0	affinity chromatography technology, two hybrid	Bennett EJ (2010), Wang J (2011)	2
ELOC	0	SPSB4	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nishiya T (2011), Lievens S (2009), Lievens S (2009), Kamura T (2004)	4
VHL	0	CDC34	3	pull down	Masson N (2001)	1
CUL2	3	ELOB	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kamura T (2001), Menon S (2008), Megumi Y (2005), Kamura T (2002), Brower CS (2002), Bennett EJ (2010), Pause A (1997), Kamura T (2004), Kelsall IR (2013)	9
BTRC	1	NEDD4	2	affinity chromatography technology, affinity chromatography technology	Liu J (2014), Liu J (2014)	2
UBE2F	1	RNF7	0	x-ray crystallography, pull down, pull down, pull down	Stanley DJ (2012), Huang DT (2009), Wang X (2015), Zhou W (2017)	4
DCUN1D3	1	ELOB	1	affinity chromatography technology	Keuss MJ (2016)	1
DCUN1D2	0	CUL4A	2	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
RNF7	0	PMAIP1	0	enzymatic study	Zhou W (2017)	1
NEDD4	2	UBE2D2	0	two hybrid, enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down	Hatakeyama S (1997), Anan T (1998), Sehat B (2008), Arevalo JC (2006), Woelk T (2006), Persaud A (2009), Zeng F (2009), Sarkari F (2013), Liu PY (2012), Sugeno N (2014), Bustos F (2015), Chesarino NM (2015), Sun M (2016)	13
CDC34	3	CUL1	7	pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology	Block K (2005), Wirbelauer C (2000), Saha A (2008), Sandoval D (2014), Wu K (2016)	5
UBE2F	1	CUL5	1	enzymatic study, enzymatic study, affinity chromatography technology	Jaeger S (2012), Stanley DJ (2012), Zhou W (2017)	3
ASB7	1	ASB4	2	affinity chromatography technology, affinity chromatography technology	Andresen CA (2014), Andresen CA (2014)	2
ASB4	2	ELOB	1	affinity chromatography technology	Ferguson JE (2007)	1
UBE2D4	0	MKRN3	2	two hybrid	Markson G (2009)	1
VCP	6	CUL5	1	affinity chromatography technology	Yu CC (2013)	1
ASB13	0	ELOC	0	affinity chromatography technology	Andresen CA (2014)	1
DCUN1D2	0	CUL4B	8	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016)	4
CARD14	6	RNF7	0	two hybrid, affinity chromatography technology	Telesio G (2017), Telesio G (2017)	2
NEDD4	2	UBE2M	0	pull down	Persaud A (2009)	1
RNF7	0	UBE2M	0	pull down	Huang DT (2009)	1
RAB40C	0	RNF7	0	affinity chromatography technology	Kamura T (2004)	1
UBE2D3	1	NEDD4	2	enzymatic study, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, pull down, pull down, pull down	Anan T (1998), Wang X (2008), Maspero E (2011), Katz M (2002), Wu K (2011), Maspero E (2013), Hong SW (2013), Zhou W (2014), Sugeno N (2014), Maspero E (2013), Miyazaki K (2003), Mari S (2014), Song F (2013), Fan CD (2013)	14
BTRC	1	ERBIN	5	bioid, affinity chromatography technology, affinity chromatography technology	Coyaud E (2015), Xie CM (2015), Xie CM (2015)	3
RNF7	0	ELOC	0	pull down, pull down	Kim DY (2013), Kershaw NJ (2014)	2
CUL3	17	ELOB	1	affinity chromatography technology	Bennett EJ (2010)	1
NEDD4L	3	RNF7	0	pull down	Persaud A (2009)	1
CUL3	17	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
CUL1	7	GHR	1	unspecified method	Bulatov E (2015)	1
NEDD4	2	RNF7	0	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Persaud A (2009), Zhou W (2014), Zhou W (2014), Zhou W (2014)	4
UBE2D4	0	RNF7	0	two hybrid	Markson G (2009)	1
DCUN1D5	0	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
DCUN1D2	0	CUL1	7	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
UBE2D1	0	UBE2D2	0	biochemical	Havugimana PC (2012)	1
CUL4B	8	ASB6	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL2	3	ELOC	0	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Kamura T (2001), Maine GN (2007), Megumi Y (2005), Mao X (2009), Lonergan KM (1998), Lonergan KM (1998), Bennett EJ (2010), Pause A (1997), Pause A (1999), Kamura T (2004), Kelsall IR (2013), Lee SB (2016)	12
CUL5	1	PMAIP1	0	affinity chromatography technology	Zhou W (2017)	1
RNF7	0	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Tan M (2010), Kuang P (2016), Kuang P (2016), Kuang P (2016)	4
SKP2	2	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down	Roe JS (2011), Roe JS (2011), Roe JS (2011)	3
CUL3	17	ERBIN	5	affinity chromatography technology	Wimuttisuk W (2014)	1
CUL5	1	VHL	0	pull down	Kamura T (2001)	1
TRIM46	3	RNF7	0	two hybrid	Woodsmith J (2012)	1
VHL	0	UBE2D1	0	pull down	Gao C (2010)	1
SPSB4	1	CUL5	1	affinity chromatography technology, affinity chromatography technology	Kamura T (2004), Huttlin EL (2017)	2
CUL4A	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Angers S (2006), Bennett EJ (2010), Bennett EJ (2010), Sertic S (2013)	5
DCUN1D2	0	CUL3	17	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	7
CUL3	17	UBE2D1	0	pull down	Sumara I (2007)	1
SOCS2	1	ELOB	1	affinity chromatography technology, biochemical	Vesterlund M (2011), Kim DY (2013)	2
UBE2D3	1	TRIM8	6	two hybrid	Markson G (2009)	1
ELOC	0	ASB2	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nie L (2011), Lievens S (2009), Bello NF (2009), Zakaria R (2013)	4
ASB12	0	ELOB	1	affinity chromatography technology	Andresen CA (2014)	1
RNF7	0	CHFR	5	two hybrid	Woodsmith J (2012)	1
ASB2	1	CUL1	7	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011)	2
SKP2	2	BTRC	1	affinity chromatography technology, pull down, affinity chromatography technology	Wei S (2012), Wei S (2012), Wei S (2012)	3
UBE2M	0	DCUN1D2	0	pull down, x-ray crystallography, affinity chromatography technology, pull down	Monda JK (2013), Monda JK (2013), Meyer-Schaller N (2009), Keuss MJ (2016)	4
SKP2	2	ELOC	0	affinity chromatography technology	Kimura Y (2007)	1
RNF7	0	ELOB	1	pull down, pull down	Kim DY (2013), Kershaw NJ (2014)	2
RNF7	0	UBE2S	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Kuang P (2016), Kuang P (2016), Kuang P (2016), Zhou W (2017)	4
CUL5	1	RAB40C	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kamura T (2004), Huttlin EL (2017)	3
UBE2M	0	DCUN1D4	0	pull down, pull down	Monda JK (2013), Keuss MJ (2016)	2
UBE2D3	1	NEDD4L	3	pull down, pull down, pull down	Maspero E (2013), Todaro DR (2017), Wang Z (2016)	3
SOCS3	0	VHL	0	affinity chromatography technology	Russell RC (2011)	1
ASB2	1	SKP2	2	affinity chromatography technology, affinity chromatography technology	Nie L (2011), Nie L (2011)	2
IKBKG	0	BTRC	1	affinity chromatography technology	Orel L (2010)	1
RNF7	0	CUL1	7	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Ohta T (1999), Kawakami T (2001), Tan M (2010), Swaroop M (2001), Huang DT (2009), Kuang P (2016), Zhou W (2017)	7
CUL5	1	CBFB	1	biochemical, pull down, pull down, pull down, pull down, pull down	Zhou X (2012), Salter JD (2012), Han X (2014), Fribourgh JL (2014), Guo Y (2014), Guo Y (2014)	6
UBE2M	0	DCUN1D5	0	pull down, affinity chromatography technology, pull down, pull down	Monda JK (2013), Bommelje CC (2013), Monda JK (2013), Keuss MJ (2016)	4
CUL4A	2	CUL1	7	biochemical	He YJ (2006)	1
UBE2D4	0	CHFR	5	two hybrid	Markson G (2009)	1
VCP	6	RNF7	0	affinity chromatography technology	Yu CC (2013)	1
ELOC	0	SPSB2	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Nishiya T (2011), Lievens S (2009), Lievens S (2009), Kamura T (2004)	4
DCUN1D4	0	CUL4A	2	pull down, enzymatic study	Monda JK (2013), Monda JK (2013)	2
RNF7	0	CUL4A	2	two hybrid, enzymatic study	Ohta T (1999), Huang DT (2009)	2
SPSB4	1	ELOB	1	affinity chromatography technology	Kamura T (2004)	1
ASB4	2	CUL2	3	affinity chromatography technology	Ferguson JE (2007)	1
UBE2D2	0	CUL3	17	pull down	Plafker KS (2009)	1
RNF7	0	CDC34	3	pull down, pull down	He H (2007), Tan M (2010)	2
RNF7	0	UBE2C	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Kuang P (2016), Kuang P (2016), Kuang P (2016), Zhou W (2017)	4
UBE2D1	0	MKRN3	2	two hybrid, two hybrid	Markson G (2009), Rolland T (2014)	2
UBE2S	2	UBE2C	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
CUL5	1	BTRC	1	affinity chromatography technology, affinity chromatography technology	Kuang P (2016), Kuang P (2016)	2
RNF7	0	CUL4B	8	enzymatic study	Huang DT (2009)	1
ASB7	1	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohroki J (2005), Bennett EJ (2010), Andresen CA (2014), Uematsu K (2016), Huttlin EL (2017)	5
RNF7	0	CUL2	3	two hybrid, enzymatic study	Ohta T (1999), Huang DT (2009)	2
ASB4	2	RNF7	0	affinity chromatography technology	Andresen CA (2014)	1
DCUN1D2	0	CUL2	3	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
BTRC	1	GHR	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	van Kerkhof P (2007), da Silva Almeida AC (2012), da Silva Almeida AC (2013), da Silva Almeida AC (2013)	4
CUL2	3	ASB2	1	affinity chromatography technology	Nie L (2011)	1
RNF7	0	UBE2D3	1	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tan M (2010), Kershaw NJ (2014), Raducu M (2016), Kuang P (2016), Kuang P (2016)	5
SPSB4	1	RNF7	0	affinity chromatography technology	Kamura T (2004)	1
CUL5	1	CUL2	3	affinity chromatography technology	Bennett EJ (2010)	1
NEDD4	2	CUL1	7	affinity chromatography technology	Liu J (2014)	1
SKP2	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Min KW (2003), Lisztwan J (1998), Lisztwan J (1998), Marti A (1999), Zheng N (2002), Menon S (2008), Chew EH (2007), Chew EH (2007), Ji P (2006), Sabile A (2006), Tan P (1999), Lin HK (2009), Nie L (2011), Chua YS (2011), Huang Z (2004), Wu J (2012), Koyama-Nasu R (2007), Bashir T (2010), Saiga T (2009), Choo YY (2011), Jonason JH (2007), Jonason JH (2007), Bennett EJ (2010), Michel JJ (1998), Carrano AC (1999), Lyapina SA (1998), Lyapina SA (1998), Wu J (2012), Yu ZK (1998), Yu ZK (1998), Rodier G (2008), Swarnalatha M (2013), Cordero-Espinoza L (2013), Yumimoto K (2013), Chung FZ (2014), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Zhang S (2016), Zhang S (2016), Huttlin EL (2017), Kuchay S (2017), Reitsma JM (2017), Reitsma JM (2017), Ma X (2017)	46
ELOC	0	ASB1	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Lievens S (2009), Mahrour N (2008), Andresen CA (2014)	3
ASB4	2	UBE2D1	0	pull down	Townley-Tilson WH (2014)	1
GLMN	2	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
GHR	1	SOCS3	0	pull down	Ram PA (1999)	1
ASB7	1	ELOB	1	affinity chromatography technology	Andresen CA (2014)	1
RNF7	0	ITM2C	3	two hybrid	Rual JF (2005)	1
RNF7	0	CUL5	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, enzymatic study, pull down, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ohta T (1999), Bennett EJ (2010), Tan M (2008), Kelsall IR (2013), Kelsall IR (2013), Zhou W (2014), Rolland T (2014), Huang DT (2009), Kim DY (2013), Kim DY (2013), Yu H (2011), Bulatov E (2015), Wang X (2015), Wang X (2015), Wang X (2015), Kershaw NJ (2014), Huttlin EL (2017), Kuang P (2016), Kuang P (2016), Zhou W (2017), Zhou W (2017)	21
NEDD4	2	CUL5	1	affinity chromatography technology	Zhou W (2014)	1
CUL5	1	ASB13	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Andresen CA (2014), Huttlin EL (2017)	3
UBE2F	1	DCUN1D3	1	pull down, x-ray crystallography	Monda JK (2013), Monda JK (2013)	2