Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
NR1D1 9572 GSK-4112 CHEMBL1961795 agonist GuideToPharmacologyInteractions
NR1D1 9572 LITHIUM CHEMBL2146126 PharmGKB
NR1D1 9572 HEMIN CHEMBL2096654 agonist GuideToPharmacologyInteractions
NR1D1 9572 SR9011 CHEMBL1961797 agonist GuideToPharmacologyInteractions
NR1D1 9572 ATENOLOL CHEMBL24 antagonist GuideToPharmacologyInteractions
NR1D1 9572 SR9009 CHEMBL1961796 agonist GuideToPharmacologyInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
NR1D1 rs939347 A lithium efficacy no Allele A is not associated with response to lithium in people with Bipolar Disorder as compared to allele G. 20348464 981750357
NR1D1 rs939347 A lithium efficacy no Full responders were compared to partial/non-responders, and allele and genotype frequencies did not differ between groups. Allele A is not associated with response to lithium in people with Bipolar Disorder as compared to allele G. 19818381 981502741
NR1D1 rs2071570 A lithium efficacy yes Allele A is not associated with response to lithium in people with Bipolar Disorder as compared to allele C. 20348464 981750364
NR1D1 rs12941497 A lithium efficacy no Full responders were compared to partial/non-responders, and allele and genotype frequencies did not differ between groups. Allele A is not associated with response to lithium in people with Bipolar Disorder as compared to allele G. 19818381 981502733
NR1D1 rs12941497 A lithium efficacy yes Allele A is not associated with response to lithium in people with Bipolar Disorder as compared to allele G. 20348464 981750351