PPI network (data source: BioGrid)

Symbol A GeneA coding DNM count Symbol B GeneB coding DNM count Interaction detection method Publication Evidence
MAP4K4 13 CDK12 3 biochemical Wan C (2015) 1
HSP90AA1 7 PRKCE 6 affinity chromatography technology, affinity chromatography technology Taipale M (2012), Budas GR (2010) 2
GRK5 7 HSP90AA1 7 affinity chromatography technology Wu Z (2012) 1
ITGB1 4 MAP4K4 13 two hybrid, pull down, affinity chromatography technology Poinat P (2002), Poinat P (2002), Poinat P (2002) 3
XPO1 8 STRN3 3 affinity chromatography technology Kirli K (2015) 1
G3BP1 4 HSP90AA1 7 affinity chromatography technology Jain S (2016) 1
NTRK1 1 MAP4K4 13 affinity chromatography technology Emdal KB (2015) 1
ATG14 1 MAP4K4 13 affinity chromatography technology Huttlin EL (2017) 1
TRIM25 5 HSP90AA1 7 affinity chromatography technology Choudhury NR (2017) 1
EGLN3 0 MAP4K4 13 affinity chromatography technology Rodriguez J (2016) 1
BRCA1 7 MAP4K4 13 unspecified method Rodriguez M (2003) 1
TMEM17 0 ITGB1 4 bioid Gupta GD (2015) 1
MOB1B 0 MAP4K4 13 bioid Couzens AL (2013) 1
HSP90AA1 7 BRCA1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Johnson N (2013), Johnson N (2013), Ertych N (2016) 3
GRK5 7 MAP4K4 13 affinity chromatography technology Wu Z (2012) 1
NTRK1 1 G3BP1 4 affinity chromatography technology Emdal KB (2015) 1
NCK2 2 MAP4K4 13 affinity chromatography technology Huttlin EL (2015) 1
PPP1CC 2 MAP4K4 13 two hybrid Fardilha M (2011) 1
XPO1 8 MAP4K4 13 affinity chromatography technology Kirli K (2015) 1
NCK2 2 MINK1 6 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
PPP1CA 3 MAP4K4 13 two hybrid Esteves SL (2012) 1
EGLN3 0 RNH1 8 affinity chromatography technology Rodriguez J (2016) 1
NTRK1 1 RNH1 8 affinity chromatography technology Emdal KB (2015) 1
EGLN3 0 PPP1CA 3 affinity chromatography technology Rodriguez J (2016) 1
LTBR 0 MAP4K4 13 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
NANOS2 0 MINK1 6 affinity chromatography technology Huttlin EL (2017) 1
PAXIP1 1 G3BP1 4 affinity chromatography technology Woods NT (2012) 1
RAP2C 0 MAP4K4 13 affinity chromatography technology Huttlin EL (2017) 1
XPO1 8 HIF1AN 0 affinity chromatography technology Kirli K (2015) 1
HSP90AA1 7 XPO1 8 affinity chromatography technology Falsone SF (2005) 1
NTRK1 1 RASA1 3 affinity chromatography technology Emdal KB (2015) 1
ZRANB1 3 FGFR1OP2 0 affinity chromatography technology Sowa ME (2009) 1
BRCA1 7 XPO1 8 affinity chromatography technology Ertych N (2016) 1
ZRANB1 3 MAP4K4 13 affinity chromatography technology Sowa ME (2009) 1
STRN3 3 FGFR1OP2 0 affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Goudreault M (2009), Couzens AL (2013), Hauri S (2013), Hein MY (2015), Hein MY (2015) 5
ZRANB1 3 STRN 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Tran H (2012), Tran H (2012) 3
OBSL1 9 XPO1 8 affinity chromatography technology Hanson D (2014) 1
NTRK1 1 XPO1 8 affinity chromatography technology Emdal KB (2015) 1
BRCA1 7 STRN 1 affinity chromatography technology Woods NT (2012) 1
OBSL1 9 PPP1CA 3 affinity chromatography technology Hanson D (2014) 1
HIF1AN 0 CNOT11 1 affinity chromatography technology Rodriguez J (2016) 1
FGFR1OP2 0 MAP4K4 13 affinity chromatography technology Hein MY (2015) 1
HEPACAM2 3 MAP4K4 13 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
RASA1 3 NCK1 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, far western blotting, pull down, affinity chromatography technology Holland SJ (1997), Ger M (2011), Ger M (2011), Ger M (2011), Ger M (2011), Ger M (2011), Ger M (2011) 7
XPO1 8 PAXIP1 1 affinity chromatography technology Kirli K (2015) 1
PTGER3 2 MAP4K4 13 affinity chromatography technology Huttlin EL (2015) 1
NTRK1 1 NOP2 4 affinity chromatography technology Emdal KB (2015) 1
PPP2CB 1 MAP4K4 13 affinity chromatography technology Hein MY (2015) 1
EGLN3 0 XPO1 8 affinity chromatography technology Rodriguez J (2016) 1
XPO1 8 CNOT11 1 affinity chromatography technology Kirli K (2015) 1
CNOT11 1 MAP4K4 13 affinity chromatography technology Huttlin EL (2017) 1
MAP4K4 13 NME7 0 two hybrid Wang J (2011) 1
PTGER3 2 SLC9A1 10 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
MANSC1 4 MAP4K4 13 affinity chromatography technology Huttlin EL (2017) 1
MAP4K4 13 RASA1 3 affinity chromatography technology Becker E (2000) 1
PAXIP1 1 PPP1CC 2 affinity chromatography technology Woods NT (2012) 1
NCK2 2 NCK1 0 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
TRIM25 5 PPP1CA 3 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 STRN3 3 affinity chromatography technology Choudhury NR (2017) 1
MAP4K4 13 PRKCE 6 two hybrid Bandyopadhyay S (2010) 1
MAP4K4 13 HIST2H2BE 1 two hybrid Bandyopadhyay S (2010) 1
NANOS2 0 CNOT11 1 affinity chromatography technology Huttlin EL (2017) 1
STRN 1 FGFR1OP2 0 affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Goudreault M (2009), Couzens AL (2013), Hauri S (2013), Hein MY (2015), Hein MY (2015) 5
EGLN3 0 CNOT11 1 affinity chromatography technology Rodriguez J (2016) 1
MAP4K4 13 MAP3K1 4 affinity chromatography technology Su YC (1997) 1
OBSL1 9 HIST2H2BE 1 affinity chromatography technology Hanson D (2014) 1
BRCA1 7 NOP2 4 affinity chromatography technology, affinity chromatography technology Hill SJ (2014), Ertych N (2016) 2
RASA1 3 G3BP1 4 affinity chromatography technology Gallouzi IE (1998) 1
HSP90AA1 7 MINK1 6 affinity chromatography technology Taipale M (2012) 1
MINK1 6 MAP4K4 13 affinity chromatography technology So J (2015) 1
NTRK1 1 PPP1CA 3 affinity chromatography technology Emdal KB (2015) 1
MAP4K4 13 GBP3 0 pull down, affinity chromatography technology, two hybrid Luan Z (2002), Luan Z (2002), Luan Z (2002) 3
STRN 1 MAP4K4 13 affinity chromatography technology Hein MY (2015) 1
TMEM17 0 MAP4K4 13 bioid Gupta GD (2015) 1
SLC25A41 0 MAP4K4 13 affinity chromatography technology Huttlin EL (2015) 1
NTRK1 1 MAP3K1 4 affinity chromatography technology Emdal KB (2015) 1
PPP1CA 3 BRCA1 7 affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology Winter SL (2007), Liu Y (2002), Liu Y (2002), Liu Y (2002), Liu Y (2002), Woods NT (2012), Chen BY (2014) 7
TRIM25 5 MAP4K4 13 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 XPO1 8 affinity chromatography technology Choudhury NR (2017) 1
EGLN3 0 BRCA1 7 affinity chromatography technology Rodriguez J (2016) 1
NTRK1 1 ITGB1 4 affinity chromatography technology Emdal KB (2015) 1
TRIM25 5 EGLN3 0 affinity chromatography technology Choudhury NR (2017) 1
MAP4K4 13 KIF5A 2 two hybrid Bandyopadhyay S (2010) 1
ZRANB1 3 STRN3 3 affinity chromatography technology, affinity chromatography technology Sowa ME (2009), Tran H (2012) 2
G3BP1 4 RNH1 8 affinity chromatography technology Jain S (2016) 1
CNTRL 5 CEP152 2 bioid Gupta GD (2015) 1
TEX264 0 MINK1 6 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
NCK1 0 MAP4K4 13 pull down, affinity chromatography technology Su YC (1997), Su YC (1997) 2
STRN3 3 MAP4K4 13 affinity chromatography technology Hein MY (2015) 1
NANOS2 0 MAP4K4 13 affinity chromatography technology Huttlin EL (2017) 1
TRIM25 5 PPP1CC 2 affinity chromatography technology Choudhury NR (2017) 1
EGLN3 0 CDK12 3 affinity chromatography technology Rodriguez J (2016) 1
BRCA1 7 TRIM25 5 affinity chromatography technology Ertych N (2016) 1
TBPL2 1 MAP4K4 13 two hybrid Nishinaka Y (2004) 1
NTRK1 1 HSP90AA1 7 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Rao R (2010), Taipale M (2012), Emdal KB (2015) 3
PPP1CA 3 XPO1 8 biochemical Kristensen AR (2012) 1
NTRK1 1 KIF26B 11 affinity chromatography technology Emdal KB (2015) 1
PPP2CB 1 FGFR1OP2 0 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017) 3
TMEM17 0 SLC9A1 10 bioid Gupta GD (2015) 1
PAXIP1 1 CDK12 3 affinity chromatography technology Woods NT (2012) 1
PPP1CC 2 PPP1CA 3 affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017), Yadav L (2017) 8
PPP2CB 1 STRN 1 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Goudreault M (2009), Glatter T (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017) 5
CNTRL 5 NME7 0 bioid Gupta GD (2015) 1
OBSL1 9 NOP2 4 affinity chromatography technology Hanson D (2014) 1
NTRK1 1 STRN 1 affinity chromatography technology Emdal KB (2015) 1
G3BP1 4 ITGB1 4 affinity chromatography technology Jain S (2016) 1
NTRK1 1 STRN3 3 affinity chromatography technology Emdal KB (2015) 1
TRIM25 5 PPP2CB 1 affinity chromatography technology Choudhury NR (2017) 1
MAP4K4 13 KIF26B 11 two hybrid Bandyopadhyay S (2010) 1
OBSL1 9 MAP4K4 13 affinity chromatography technology Hanson D (2014) 1
TEX264 0 MAP4K4 13 affinity chromatography technology, affinity chromatography technology Huttlin EL (2015), Huttlin EL (2017) 2
CEP152 2 MAP4K4 13 bioid Gupta GD (2015) 1
TRIM25 5 LTBR 0 affinity chromatography technology Choudhury NR (2017) 1
TRIM25 5 G3BP1 4 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Choudhury NR (2017), Choudhury NR (2017), Jain S (2016) 3
RNH1 8 MAP4K4 13 affinity chromatography technology Hein MY (2015) 1
PAXIP1 1 STRN 1 affinity chromatography technology Woods NT (2012) 1
PPP2CB 1 STRN3 3 affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Goudreault M (2009), Glatter T (2009), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017) 6
XPO1 8 MAP3K1 4 affinity chromatography technology Kirli K (2015) 1
TRIM25 5 MINK1 6 affinity chromatography technology Choudhury NR (2017) 1
MINK1 6 NCK1 0 two hybrid, pull down Hu Y (2004), Hu Y (2004) 2
SLC9A1 10 HSP90AA1 7 affinity chromatography technology Amith SR (2017) 1
CNTRL 5 MAP4K4 13 bioid Gupta GD (2015) 1
PAXIP1 1 MAP4K4 13 affinity chromatography technology Woods NT (2012) 1
HIF1AN 0 MAP4K4 13 affinity chromatography technology Rodriguez J (2016) 1
MAP4K4 13 SLC9A1 10 two hybrid Bandyopadhyay S (2010) 1
STRN 1 STRN3 3 affinity chromatography technology, affinity chromatography technology, biochemical, bioid, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology Goudreault M (2009), Goudreault M (2009), Havugimana PC (2012), Couzens AL (2013), Couzens AL (2013), Hauri S (2013), Hauri S (2013), Hein MY (2015), Hein MY (2015) 9
NOP2 4 MINK1 6 biochemical Wan C (2015) 1
EGLN3 0 PPP1CC 2 affinity chromatography technology Rodriguez J (2016) 1
EGLN3 0 OBSL1 9 affinity chromatography technology Rodriguez J (2016) 1
PAXIP1 1 NOP2 4 affinity chromatography technology Woods NT (2012) 1
BRCA1 7 MAP3K1 4 two hybrid Woods NT (2012) 1
HSP90AA1 7 MAP4K4 13 affinity chromatography technology Taipale M (2012) 1
MAP4K4 13 NOP2 4 biochemical Wan C (2015) 1
G3BP1 4 MAP4K4 13 affinity chromatography technology Jain S (2016) 1