Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
KL	rs36217263	A/del + del/del	Beta Blocking Agents	efficacy	yes	Deletion of at least one allele of rs36217263 is associated with poor response to beta-blockers (dominant model of inheritance). In subgroup analysis, this association is observed among participants using cardioselective beta-blockers (crude OR = 5.60; P = 0.008) but not carvedilol (crude OR = 2.56; P = 0.67), suggesting rs36217263 is associated with poor response to cardioselective beta-blockers.	Genotypes A/del + del/del are associated with decreased response to Beta Blocking Agents in people with Hypertension as compared to genotype AA.	31350855	1450943742