PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
SP1	0	SMARCA4	19	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kadam S (2000), Liu H (2002), Liu H (2002), Ma Z (2004), Saladi SV (2010)	5
RELA	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Zhong H (2002), Zhong H (2002), Zhong H (2002), Zhong H (2002), Ashburner BP (2001), Ashburner BP (2001), OShea JM (2010), OShea JM (2010), Liu Y (2006), Cao W (2006), Hu J (2004), Hu J (2004), Sun JM (2007), Deckmann K (2012)	15
PRKCD	2	SP1	0	affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai PF (2011), Tsai PF (2011), Tsai PF (2011), Ito H (2012), Xu K (2009), Xu K (2009)	6
PPARG	0	CREBBP	29	pull down, two hybrid, unspecified method, pull down, two hybrid, pull down, unspecified method	Li M (2000), Chen Q (2004), Lee G (2002), Carmona MC (2007), Carmona MC (2007), Jeninga EH (2007), Koppen A (2009)	7
VHL	0	PRKCD	2	fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Iturrioz X (2006), Iturrioz X (2006), Yong HJ (2017), Yong HJ (2017)	4
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
CREBBP	29	ELK1	2	far western blotting	Janknecht R (1996)	1
SMARCA4	19	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Sif S (2001), Qiu Z (2008), Xu Z (2006), Pal S (2003), Battaglioli E (2002), Tando T (2010), Hang CT (2010), Shen JP (2017)	8
RELA	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HUWE1	22	KLF4	2	enzymatic study, affinity chromatography technology	Hao Z (2017), Hao Z (2017)	2
HDAC7	4	HDAC2	1	pull down	Dressel U (2001)	1
HDAC5	4	CTBP1	2	pull down	Zhang CL (2001)	1
KLF4	2	FBXO32	2	affinity chromatography technology, affinity chromatography technology	Zhou H (2017), Zhou H (2017)	2
KLF4	2	HDAC1	4	pull down	Noti JD (2005)	1
CTBP1	2	CREBBP	29	affinity chromatography technology, pull down	Senyuk V (2005), Kim JH (2005)	2
SETD7	2	RELA	1	enzymatic study, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study	Yang XD (2009), Yang XD (2009), Yang XD (2009), Ea CK (2009), Li Y (2008), Levy D (2011)	6
CREBBP	29	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, genetic interference, genetic interference, genetic interference, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Jang HD (2004), Zhong H (2002), Zhong H (2002), Parry GC (1997), Parry GC (1997), Parry GC (1997), Aarnisalo P (1998), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Liu GH (2008), Vanden Berghe W (1999), Naeaer AM (1999), Merika M (1998), Park J (2007), Verma UN (2004), Verma UN (2004), Verma UN (2004), Johnson J (2007), Aksoy E (2007), Azran I (2005), Silverman ES (1998), Huang WC (2007), Huang WC (2007), Aarnisalo P (1998), Kim HJ (1999), Hsu DS (2014), Chen Y (2015), Huang SM (2002)	30
FBXO7	1	HUWE1	22	affinity chromatography technology	Teixeira FR (2016)	1
VHL	0	APP	1	pull down	Olah J (2011)	1
AURKA	1	SKP1	0	affinity chromatography technology	Fogeron ML (2013)	1
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
SP1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Won J (2002), Zhang Y (2002), Sun JM (2002), Glasspool RM (2005), Duan H (2005), Sekhavat A (2007), Itoh Y (2007), Marshall GM (2010), Tsai PF (2011), Schnur N (2007)	10
AURKA	1	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
AURKA	1	HDAC2	1	pull down	Pugacheva EN (2007)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
PPARG	0	SP1	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Costa V (2008), Singh AK (2010), Singh AK (2010), Zhang XH (2012), Zhang XH (2012), Zurlo D (2014), Zurlo D (2014)	7
FBXO32	2	SKP1	0	pull down, affinity chromatography technology	Gomes MD (2001), Al-Yacoub N (2016)	2
KAT5	1	APP	1	two hybrid, fluorescent resonance energy transfe, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down	Sumioka A (2005), Kinoshita A (2002), von Rotz RC (2004), von Rotz RC (2004), von Rotz RC (2004), Cao X (2004), Li Q (2004), Olah J (2011)	8
CDH1	4	EP300	36	affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005)	2
SP1	0	RELA	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuang PP (2002), Sif S (1994), Sif S (1994), Kao YS (2008), Kao YS (2008), Benjamin JT (2010), Beauchef G (2012), Xu Y (2008)	8
PRKCD	2	HDAC5	4	enzymatic study	Huynh QK (2011)	1
VHL	0	ELOB	1	affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Ohh M (1999), Min JH (2002), Hacker KE (2008), Menon S (2008), Kamura T (2002), Kamura T (2002), Kuznetsova AV (2003), Cockman ME (2000), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Kinoshita K (2007), Lai Y (2012), Mahrour N (2008), Mahrour N (2008), Grosfeld A (2007), Foxler DE (2012), He X (2011), McClellan AJ (2005), Bex C (2007), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Feldman DE (2003), Kibel A (1995), Kibel A (1995), Pause A (1999), Pause A (1999), Duan DR (1995), Kamura T (2004), Russell RC (2008), Russell RC (2008), Essers PB (2014), Gerez J (2015), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Zhang C (2016), Huttlin EL (2017), Sun W (2017)	43
HDAC7	4	HDAC5	4	pull down	Dressel U (2001)	1
CREBBP	29	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Ito K (2000), Adenuga D (2010)	2
CTBP1	2	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Koipally J (2000), Glasspool RM (2005), Kuppuswamy M (2008), Kuppuswamy M (2008), Mendez LM (2008)	5
KLF4	2	VHL	0	affinity chromatography technology, pull down	Gamper AM (2012), Gamper AM (2012)	2
SETD7	2	KLF4	2	enzymatic study	Fang L (2014)	1
FBXO32	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Al-Yacoub N (2016), Al-Yacoub N (2016), Reitsma JM (2017)	3
ELK1	2	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
KLF4	2	KAT5	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Ai W (2007), Ai W (2007), Ai W (2007), Ai W (2007)	4
CREBBP	29	KAT5	1	affinity chromatography technology	Col E (2005)	1
KLF4	2	FBXO22	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian X (2015), Tian X (2015), Tian X (2015)	3
EP300	36	KLF4	2	pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Evans PM (2007), Yu K (2011), Yu K (2011), Zhang R (2010), Allen KL (2011)	5
PPARG	0	SMARCA4	19	affinity chromatography technology	Debril MB (2004)	1
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
KAT5	1	VHL	0	affinity chromatography technology, affinity chromatography technology	Roe JS (2011), Roe JS (2011)	2
ELK1	2	KLF4	2	affinity chromatography technology, affinity chromatography technology	Yoshida T (2008), Yoshida T (2008)	2
KLF4	2	ELOB	1	affinity chromatography technology	Gamper AM (2012)	1
PRKCD	2	KLF4	2	affinity chromatography technology, affinity chromatography technology	Zhang XH (2012), Zhang XH (2012)	2
RELA	1	PPARG	0	affinity chromatography technology, enzymatic study, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Hou Y (2012), Hou Y (2012), Lu X (2013), Chen F (2003), Chen F (2003), Perez A (2008), Jeninga EH (2007)	7
VHL	0	AURKA	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	Martin B (2013), Martin B (2013), Hasanov E (2017), Hasanov E (2017), Hasanov E (2017)	5
KLF4	2	SMARCA4	19	affinity chromatography technology	Mak AB (2010)	1
PPARG	0	KAT5	1	pull down, unspecified method	van Beekum O (2008), Lee G (2002)	2
KLF4	2	CTBP1	2	affinity chromatography technology, affinity chromatography technology	Liu G (2009), Liu G (2009)	2
ELK1	2	HDAC1	4	pull down	Yang SH (2001)	1
VHL	0	SP1	0	affinity chromatography technology, affinity chromatography technology, pull down	Yuen JS (2007), Mukhopadhyay D (1997), Mukhopadhyay D (1997)	3
CREBBP	29	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goto T (2006), Leclerc GJ (2010), Chuang JY (2012), Guo W (2014)	4
VHL	0	CUL2	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ohh M (1999), Kamura T (2001), Hacker KE (2008), Hacker KE (2008), Menon S (2008), Chew EH (2007), Ietta F (2006), Megumi Y (2005), Kamura T (2002), Kuznetsova AV (2003), Hansen WJ (2002), Cockman ME (2000), Lisztwan J (1999), Lisztwan J (1999), Sufan RI (2006), Sufan RI (2009), Stickle NH (2004), Lai Y (2011), Norman JA (2006), Knauth K (2006), Lonergan KM (1998), Lai Y (2012), Miller F (2005), Mahrour N (2008), Grosfeld A (2007), Russell RC (2011), Foxler DE (2012), Bonicalzi ME (2001), Bennett EJ (2010), Kanaya K (2002), Liakopoulos D (1999), Pause A (1997), Pause A (1997), Pause A (1997), Iliopoulos O (1998), Pause A (1999), Pause A (1999), Xin H (2011), Kamura T (2004), Kamura T (2004), Heir P (2013), Russell RC (2008), Russell RC (2008), Essers PB (2014), Nguyen HC (2015), Lee SB (2016), Uchida T (2016), Heir P (2016), Chen K (2016), Uematsu K (2016), Huttlin EL (2017), Sun W (2017), Sun W (2017)	54
KLF4	2	APP	1	pull down	Olah J (2011)	1
CDH1	4	HDAC2	1	biochemical, affinity chromatography technology, imaging technique	Yoon YM (2004), Yoon YM (2004), Chen TC (2014)	3
KAT5	1	RELA	1	affinity chromatography technology, affinity chromatography technology, two hybrid	Kim JW (2012), Kim JW (2012), Kim JW (2012)	3
KLF4	2	HDAC5	4	affinity chromatography technology, affinity chromatography technology	Yoshida T (2008), Yoshida T (2008)	2
HDAC2	1	VHL	0	pull down, affinity chromatography technology, genetic interference	Mahon PC (2001), Hwang IY (2012), Shen JP (2017)	3
KLF4	2	HDAC2	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Meng F (2009), Meng F (2009), Noti JD (2005), Yu K (2011), Yu K (2011)	5
HUWE1	22	HDAC2	1	affinity chromatography technology, enzymatic study	Zhang J (2011), Zhang J (2011)	2
ELK1	2	EP300	36	genetic interference, pull down, affinity chromatography technology	Li QJ (2003), Li QJ (2003), Li QJ (2003)	3
CUL2	3	ELOB	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kamura T (2001), Menon S (2008), Megumi Y (2005), Kamura T (2002), Brower CS (2002), Bennett EJ (2010), Pause A (1997), Kamura T (2004), Kelsall IR (2013)	9
PRKCD	2	APP	1	pull down	Olah J (2011)	1
FBXO7	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Kirk R (2008), Hsu JM (2004), Hagens O (2006), Bennett EJ (2010), Hein MY (2015), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Reitsma JM (2017), Reitsma JM (2017)	11
PPARG	0	APP	1	pull down	Olah J (2011)	1
SP1	0	KLF4	2	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Zhang W (1998), Zhang XH (2012), Zhang XH (2012), Zhang XH (2012), Zhang XH (2012)	5
RELA	1	CUL2	3	affinity chromatography technology, affinity chromatography technology	Geng H (2009), Wang Y (2014)	2
CDH1	4	HDAC1	4	affinity chromatography technology, biochemical	Yoon YM (2004), Yoon YM (2004)	2
KLF4	2	CDH1	4	affinity chromatography technology, affinity chromatography technology	Hu D (2011), Hu D (2011)	2
RELA	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kiernan R (2003), Yu Z (2002), Yu Z (2002), Ito K (2001), Ito K (2000), Sun JM (2007), Adenuga D (2010), Wang H (2010), Chen TC (2014)	9
SMARCA4	19	CREBBP	29	genetic interference	DiRenzo J (2000)	1
HDAC1	4	CTBP1	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Zhang CL (2001), Melhuish TA (2000), Sundqvist A (1998), Jin W (2008), Joshi P (2013)	5
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
HDAC1	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mayanil CS (2006), Chuang HC (2006), Chuang HC (2006)	3
CDH1	4	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005)	2
HDAC5	4	HDAC1	4	affinity chromatography technology	Greco TM (2011)	1
KLF4	2	PPARG	0	affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Zhang XH (2012), Zhang XH (2012), Zhang XH (2012), Zhang XH (2012)	4
HDAC7	4	EP300	36	affinity chromatography technology	Kato H (2004)	1
KLF4	2	SKP1	0	affinity chromatography technology	Tian X (2015)	1
VHL	0	HUWE1	22	affinity chromatography technology	Zhang C (2016)	1
FBXO7	1	SKP1	0	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cenciarelli C (1999), Cenciarelli C (1999), Cenciarelli C (1999), Hsu JM (2004), Nelson DE (2011), Hagens O (2006), Kang J (2014), Winston JT (1999), Hein MY (2015), Hein MY (2015), Vingill S (2016), Vingill S (2016), Huttlin EL (2017), Teixeira FR (2016), Teixeira FR (2016), Hauri S (2016)	16
PPARG	0	HDAC1	4	pull down, affinity chromatography technology, affinity chromatography technology	Yoo EJ (2006), Yoo EJ (2006), Pancione M (2010)	3
EP300	36	PPARG	0	pull down, fluorescent resonance energy transfe, affinity chromatography technology, pull down, two hybrid, fluorescent resonance energy transfe, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, affinity chromatography technology	Fajas L (2002), Iannone MA (2001), Gelman L (1999), Gelman L (1999), Gelman L (1999), Feige JN (2007), Feige JN (2007), Debril MB (2004), Subbaramaiah K (2012), Lee G (2002), Koppen A (2009), Wang C (2001)	12
KLF4	2	CUL2	3	affinity chromatography technology	Gamper AM (2012)	1
HDAC7	4	HDAC1	4	pull down	Dressel U (2001)	1
KLF6	0	SP1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Botella LM (2002), Botella LM (2002), Gong MZ (2011), DeKelver RC (2013)	4
EP300	36	KAT5	1	affinity chromatography technology, affinity chromatography technology	Col E (2005), Col E (2005)	2
FBXO32	2	CTBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sahu SK (2017), Sahu SK (2017), Sahu SK (2017)	3
KLF4	2	HDAC7	4	affinity chromatography technology, affinity chromatography technology	Ai W (2007), Ai W (2007)	2
PRKCD	2	EP300	36	enzymatic study	Yuan LW (2000)	1
EP300	36	RELA	1	enzymatic study, two hybrid, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Hiroi M (2003), Nicot C (2001), Kim RH (2001), Hassa PO (2008), Hassa PO (2008), Hu J (2004), Naeaer AM (1999), Lee IT (2010), Nehra R (2010), Hsu HC (2007), Hsu HC (2007), Saha RN (2007), Saha RN (2007), Hassa PO (2003), Hassa PO (2003), Mendonca DB (2011), Chen W (2008), Chen LF (2002), OHara A (2014), Lu Y (2013), Lu Y (2013), Ren YB (2015), Chen LF (2005), Chen LF (2005), Chen LF (2005), Deng WG (2003)	31
HDAC1	4	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Qiu Z (2008), Battaglioli E (2002), Hang CT (2010), DiRenzo J (2000)	4
KLF6	0	APP	1	pull down	Olah J (2011)	1
FBXO22	1	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2007), Hein MY (2015), Tian X (2015), Hauri S (2016)	4
CTBP1	2	SP1	0	affinity chromatography technology, affinity chromatography technology	Glasspool RM (2005), Glasspool RM (2005)	2
KLF6	0	KLF4	2	affinity chromatography technology	Okano J (2000)	1
HDAC7	4	KAT5	1	affinity chromatography technology, two hybrid	Xiao H (2003), Xiao H (2003)	2
AURKA	1	KLF4	2	affinity chromatography technology	Hein MY (2015)	1
HDAC1	4	VHL	0	pull down, affinity chromatography technology	Mahon PC (2001), Hwang IY (2012)	2
CTBP1	2	EP300	36	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Senyuk V (2005), Kim JH (2005), Kim JH (2005), Kim JH (2005)	4
EP300	36	VHL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2011), Roe JS (2011), Ji W (2014), Chen K (2015)	5
KLF4	2	CUL1	7	affinity chromatography technology	Tian X (2015)	1
CUL1	7	FBXO22	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Liu B (2012), Reitsma JM (2017)	3
SP1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Padova M (2003), Singh J (2002), Zhang Y (2002), Sun JM (2002), Gao J (2009), Shon JK (2009), Mottet D (2009), Goto T (2006), Hung JJ (2006), Lagger G (2003), Choi HS (2002), Choi HS (2002), Kang JE (2005), Kang JE (2005), Kang JE (2005), Gan Y (2005), Gan Y (2005), Duan H (2005), Varshochi R (2005), Varshochi R (2005), Plaisance V (2005), Walker GE (2001), Walker GE (2001), Ammanamanchi S (2004), Doetzlhofer A (1999), Sekhavat A (2007), Liu T (2007), Enya K (2008), Liu S (2010), Leclerc GJ (2010), Leclerc GJ (2010), Wong CY (2011), Schnur N (2007)	33
KAT5	1	HDAC1	4	affinity chromatography technology	Du Z (2010)	1
KLF4	2	RELA	1	affinity chromatography technology	Zhang XH (2012)	1
BAALC	0	KLF4	2	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Morita K (2015), Morita K (2015), Morita K (2015), Morita K (2015), Morita K (2015)	5
SETD7	2	SMARCA4	19	affinity chromatography technology	Okabe J (2012)	1
CREBBP	29	KLF4	2	pull down, affinity chromatography technology, enzymatic study, imaging technique, imaging technique	Geiman DE (2000), Geiman DE (2000), Evans PM (2007), Kalra IS (2011), Allen KL (2011)	5
FBXO7	1	KLF4	2	enzymatic study	Teixeira FR (2016)	1