PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MAPKAPK2	1	UBE2J1	1	enzymatic study	Menon MB (2013)	1
COPS5	0	TRIM28	1	affinity chromatography technology	Bennett EJ (2010)	1
MAP2K6	2	MAPK14	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, fluorescent resonance energy transfe	Sanz-Moreno V (2003), Raingeaud J (1996), Stein B (1996), Chen Z (2001), Casar B (2007), Xia Y (1998), ter Haar E (2007), Ivanov AA (2017)	8
HNRNPL	3	AGO2	10	affinity chromatography technology	Fei T (2017)	1
CUL3	17	YWHAZ	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	HNRNPL	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei T (2017)	2
NXF1	0	SHC1	0	affinity chromatography technology	Castello A (2012)	1
COPS5	0	ESR1	0	affinity chromatography technology	Callige M (2005)	1
YWHAZ	1	HNRNPL	3	affinity chromatography technology	Ewing RM (2007)	1
MAPK14	0	MAPK1	1	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology	Sanz-Moreno V (2003), Tanoue T (2001), Srivastav RK (2011), Chan PM (2008)	4
MAPKAPK2	1	PHC2	3	two hybrid, affinity chromatography technology, protein complementation assay	Yannoni YM (2004), Yannoni YM (2004), Srivastav RK (2011)	3
HNRNPL	3	HNRNPA0	1	biochemical	Havugimana PC (2012)	1
XPO1	8	TRIM29	2	affinity chromatography technology	Kirli K (2015)	1
PIAS2	2	ESR1	0	pull down	Kotaja N (2000)	1
NXF1	0	STAT3	0	affinity chromatography technology	Castello A (2012)	1
MAPK14	0	LIMK1	3	enzymatic study	Kobayashi M (2006)	1
THAP12	0	MAPKAPK2	1	affinity chromatography technology	Luig C (2010)	1
CUL3	17	DDX5	2	affinity chromatography technology	Bennett EJ (2010)	1
HSPB1	2	DES	1	two hybrid	Katsogiannou M (2014)	1
MAPK1	1	HSF1	1	affinity chromatography technology, pull down	Dai R (2000), Dai R (2000)	2
BCL2L1	0	BECN1	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liang XH (1998), Wang J (2008), Wang J (2008), Tang Y (2012), Noble CG (2008), Noble CG (2008), Pimkina J (2009), Pimkina J (2009), Zalckvar E (2009), Luo S (2010)	10
AKT1	1	ZFP36L1	1	enzymatic study	Benjamin D (2006)	1
NXF1	0	MAPKAPK2	1	affinity chromatography technology	Castello A (2012)	1
YWHAZ	1	CEP131	9	pull down, affinity chromatography technology	Tollenaere MA (2015), Tollenaere MA (2015)	2
MAPKAPK2	1	CEP131	9	enzymatic study	Tollenaere MA (2015)	1
AKT1	1	ESR1	0	enzymatic study	Campbell RA (2001)	1
MAPKAPK2	1	HNRNPA0	1	enzymatic study	Rousseau S (2002)	1
ELAVL1	0	LIMK1	3	affinity chromatography technology	Abdelmohsen K (2009)	1
COPS5	0	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	UBE2J1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
ZFP36L1	1	MAPK14	0	two hybrid, affinity chromatography technology, enzymatic study	Rual JF (2005), Rual JF (2005), Benjamin D (2006)	3
CUL3	17	HNRNPA0	1	affinity chromatography technology	Bennett EJ (2010)	1
MAPKAPK2	1	ZFP36	2	enzymatic study, enzymatic study	Chrestensen CA (2004), Maitra S (2008)	2
MAPK14	0	BCL2L1	0	enzymatic study	Wang J (2012)	1
HNRNPL	3	TCF3	7	affinity chromatography technology	Fei T (2017)	1
YWHAZ	1	MAPKAPK2	1	pull down, pull down, enzymatic study	Powell DW (2003), Powell DW (2003), Powell DW (2003)	3
TRIM28	1	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology	Tsuruma R (2008), Tsuruma R (2008), Tsuruma R (2008)	3
XPO1	8	CSNK2B	5	affinity chromatography technology	Kirli K (2015)	1
ESR1	0	MAPKAPK2	1	affinity chromatography technology	Tarallo R (2011)	1
XPO1	8	DDX5	2	affinity chromatography technology	Kirli K (2015)	1
MOV10	6	STAT3	0	affinity chromatography technology	Castello A (2012)	1
MAPKAPK2	1	TRIM29	2	enzymatic study	Wang L (2014)	1
MAP2K6	2	MAPKAPK2	1	enzymatic study	ter Haar E (2007)	1
CUL3	17	MOV10	6	affinity chromatography technology	Bennett EJ (2010)	1
CUL3	17	MAPKAPK2	1	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	TRIM28	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang C (2005), Wang C (2005), Wang C (2005), Gilmore-Hebert M (2010), Okamoto K (2006), Okamoto K (2006), Okamoto K (2006)	7
PLK1	0	HSF1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology	Lee YJ (2008), Lee YJ (2008), Boldt K (2016)	3
CSNK2B	5	PHC2	3	two hybrid	Wang J (2011)	1
CSNK2B	5	MAPK14	0	affinity chromatography technology, affinity chromatography technology	Tsuchiya Y (2010), Tsuchiya Y (2010)	2
XPO1	8	CDC25B	4	affinity chromatography technology	Kirli K (2015)	1
ELAVL1	0	AGO2	10	affinity chromatography technology, affinity chromatography technology	Abdelmohsen K (2009), Balkhi MY (2013)	2
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
YWHAZ	1	COPS5	0	two hybrid, affinity chromatography technology	Bandyopadhyay S (2010), Bennett EJ (2010)	2
MAPKAPK2	1	HSPB1	2	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, imaging technique, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Rane MJ (2001), Uddin S (2002), Coxon PY (2003), Rogalla T (1999), Werz O (2002), Clifton AD (1996), Rane MJ (2001), Sun L (2007), Chen TC (2014), Krump E (1997), Chrestensen CA (2004), Chang E (2011), Maitra S (2008), Rane MJ (2003), Singh S (2003), Chen G (2000), Eyers CE (2005), Tollenaere MA (2015)	18
STAT3	0	MAPK1	1	affinity chromatography technology	Lo RK (2006)	1
MAPK1	1	SHC1	0	affinity chromatography technology	Dinerstein-Cali H (2000)	1
ELAVL1	0	MAPKAPK2	1	affinity chromatography technology	Abdelmohsen K (2009)	1
AKT1	1	MAPK14	0	affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Rane MJ (2001), Rane MJ (2001), Hartman AD (2006), Rane MJ (2001), Rane MJ (2001), Ivanov AA (2017)	6
CDC25B	4	YWHAZ	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mils V (2000), Mils V (2000), Hein MY (2015), Li X (2016), Huttlin EL (2017)	5
MAPK11	1	MAPK14	0	two hybrid, affinity chromatography technology	Vinayagam A (2011), Varjosalo M (2013)	2
MAPKAPK2	1	LIMK1	3	enzymatic study	Kobayashi M (2006)	1
ELAVL1	0	XPO1	8	affinity chromatography technology	Abdelmohsen K (2009)	1
PHC2	3	PLK1	0	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
NXF1	0	DDX5	2	affinity chromatography technology	Castello A (2012)	1
COPS5	0	CUL3	17	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	8
NXF1	0	XPO1	8	affinity chromatography technology	Bachi A (2000)	1
ELAVL1	0	HNRNPA0	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CUL3	17	TRIM28	1	affinity chromatography technology	Bennett EJ (2010)	1
PLK1	0	BCL2L1	0	enzymatic study	Wang J (2012)	1
ESR1	0	CDC25B	4	two hybrid, affinity chromatography technology, pull down	Ma ZQ (2001), Ma ZQ (2001), Ma ZQ (2001)	3
ELAVL1	0	TCF3	7	affinity chromatography technology, affinity chromatography technology	Abdelmohsen K (2009), Teachenor R (2012)	2
XPO1	8	TCF3	7	affinity chromatography technology	Kirli K (2015)	1
MAPKAPK2	1	RCSD1	2	enzymatic study	Eyers CE (2005)	1
MAPKAPK2	1	ATF1	0	enzymatic study	Mayo LD (2001)	1
AKT1	1	PIAS2	2	two hybrid, imaging technique	Depaux A (2007), Chen TC (2014)	2
MAP2K6	2	BECN1	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STAT3	0	COPS5	0	affinity chromatography technology	Nishimoto A (2013)	1
HSPB1	2	XPO1	8	two hybrid	Katsogiannou M (2014)	1
TCF3	7	MAPKAPK2	1	pull down	Neufeld B (2000)	1
COPS5	0	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
XPO1	8	ZFP36L1	1	affinity chromatography technology	Kirli K (2015)	1
MAPKAPK2	1	MAPK3	4	protein complementation assay, enzymatic study	Srivastav RK (2011), Coxon PY (2003)	2
MAPK1	1	CHEK1	2	biochemical	Wan C (2015)	1
MAPKAPK2	1	EGF	2	genetic interference	Deak M (1998)	1
MAPKAPK2	1	BECN1	2	enzymatic study	Wei Y (2015)	1
MAPKAPK5	0	MAPK1	1	imaging technique	Chen TC (2014)	1
MAPK14	0	CDC25B	4	enzymatic study, pull down	Bulavin DV (2001), Bulavin DV (2001)	2
MAPK14	0	HSPB1	2	enzymatic study	Morley SJ (2000)	1
MAP2K6	2	MAPK1	1	enzymatic study	Kumar S (1999)	1
MOV10	6	SHC1	0	affinity chromatography technology	Castello A (2012)	1
CUL3	17	AGO2	10	affinity chromatography technology	Bennett EJ (2010)	1
MAPKAPK2	1	DES	1	two hybrid	Yannoni YM (2004)	1
NXF1	0	CSNK2B	5	affinity chromatography technology	Castello A (2012)	1
MAPKAPK2	1	HSF1	1	enzymatic study, affinity chromatography technology	Wang X (2006), Wang X (2006)	2
CHEK1	2	BCL2L1	0	enzymatic study	Wang J (2012)	1
MOV10	6	TRIM29	2	affinity chromatography technology	Castello A (2012)	1
ELAVL1	0	PABPC1	5	affinity chromatography technology	Abdelmohsen K (2009)	1
ESR1	0	CUL3	17	affinity chromatography technology	Byun B (2008)	1
MAPKAPK2	1	PIAS2	2	enzymatic study	Heo KS (2013)	1
AKT1	1	CHEK1	2	genetic interference	Shen JP (2017)	1
MAPKAPK2	1	DDX5	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Hong S (2013), Hong S (2013), Hong S (2013)	3
MAPK11	1	MAPKAPK2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Janknecht R (2001), Janknecht R (2001)	3
AKT1	1	HSPB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, enzymatic study	Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Wu R (2007), Wu R (2007), Wu R (2007), Rane MJ (2003), Rane MJ (2003), Rane MJ (2003)	9
NXF1	0	YWHAZ	1	affinity chromatography technology	Castello A (2012)	1
XPO1	8	ESR1	0	affinity chromatography technology	Castoria G (2012)	1
COPS5	0	PABPC1	5	affinity chromatography technology	Bennett EJ (2010)	1
MAPK3	4	MAPK1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Wang J (2009), Wang J (2009), Wan C (2015), Hu B (2006)	6
MOV10	6	MAPKAPK2	1	affinity chromatography technology	Castello A (2012)	1
ELAVL1	0	ARPC5	2	affinity chromatography technology	Abdelmohsen K (2009)	1
AGO2	10	PABPC1	5	affinity chromatography technology	Fabian MR (2009)	1
MAPKAPK5	0	HSPB1	2	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study	New L (1998), Kostenko S (2009), Kostenko S (2009), Kostenko S (2009), Chen G (2000)	5
MAPKAPK2	1	TRIM28	1	enzymatic study	King CA (2013)	1
CUL3	17	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
CHEK1	2	XPO1	8	pull down	Jiang K (2003)	1
NXF1	0	TRIM29	2	affinity chromatography technology	Castello A (2012)	1
MAPK3	4	ETV1	1	enzymatic study	Janknecht R (2001)	1
MAPKAPK2	1	AGO2	10	enzymatic study	Zeng Y (2008)	1
ESR1	0	HNRNPA0	1	affinity chromatography technology	Tarallo R (2011)	1
HSPB1	2	YWHAZ	1	two hybrid	Katsogiannou M (2014)	1
MAPKAPK2	1	PLK1	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Tang J (2008), Tang J (2008), Tang J (2008)	3
MAPKAPK2	1	MAPK14	0	affinity chromatography technology, protein complementation assay, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Rane MJ (2001), Srivastav RK (2011), Wang J (2011), Varjosalo M (2013), Rane MJ (2001), White A (2007), ter Haar E (2007), Varjosalo M (2013), Gum RJ (1999), Gum RJ (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Smith JA (2000), Huttlin EL (2017)	16
MAPK1	1	MAPKAPK2	1	affinity chromatography technology, protein complementation assay, enzymatic study, affinity chromatography technology	Yannoni YM (2004), Srivastav RK (2011), Powell DW (2003), Krump E (1997)	4
XPO1	8	ZFP36	2	affinity chromatography technology	Kirli K (2015)	1
MAPKAPK2	1	CHEK1	2	genetic interference	Reinhardt HC (2010)	1
MAPKAPK2	1	SHC1	0	two hybrid, affinity chromatography technology, enzymatic study	Yannoni YM (2004), Yannoni YM (2004), Yannoni YM (2004)	3
MAPKAPK2	1	PARN	2	enzymatic study	Reinhardt HC (2010)	1
MDM2	2	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Lin HK (2002), Ogawara Y (2002), Zhou BP (2001), Zhou BP (2001), Kim CK (2011), Kim CK (2011), Zhu QS (2011), Milne D (2004), Deep G (2008), Deep G (2008), Chen TC (2014)	11
MAPKAPK2	1	MAPKAPK2	1	protein complementation assay, x-ray crystallography, enzymatic study, enzymatic study	Srivastav RK (2011), Fujino A (2010), Krump E (1997), Tang J (2008)	4
HNRNPL	3	ETV1	1	affinity chromatography technology	Fei T (2017)	1
MAPK14	0	COPS5	0	two hybrid	Wang J (2008)	1
ELAVL1	0	HNRNPL	3	affinity chromatography technology	Abdelmohsen K (2009)	1
XPO1	8	MAPKAPK2	1	affinity chromatography technology	Kirli K (2015)	1
COPS5	0	AGO2	10	affinity chromatography technology	Bennett EJ (2010)	1
HSPB1	2	HSF1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brunet Simioni M (2009), Brunet Simioni M (2009), Taipale M (2014), Taipale M (2014)	4
COPS5	0	PLK1	0	affinity chromatography technology	Bennett EJ (2010)	1
MAPKAPK5	0	MAPKAPK2	1	protein complementation assay, affinity chromatography technology	Srivastav RK (2011), Srivastav RK (2011)	2
XPO1	8	SHC1	0	affinity chromatography technology	Kirli K (2015)	1
YWHAZ	1	LIMK1	3	two hybrid, pull down	Birkenfeld J (2003), Birkenfeld J (2003)	2
SHC1	0	DDX5	2	affinity chromatography technology	Brehme M (2009)	1
AKT1	1	BCL2L1	0	enzymatic study	Qi XJ (2006)	1
MAPKAPK2	1	ETV1	1	enzymatic study	Janknecht R (2001)	1
CSNK2B	5	MDM2	2	enzymatic study	Goetz C (1999)	1
BECN1	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CHEK1	2	CDC25B	4	enzymatic study, pull down	Sanchez Y (1997), Sanchez Y (1997)	2
COPS5	0	MOV10	6	affinity chromatography technology	Bennett EJ (2010)	1
PLK1	0	MDM2	2	enzymatic study, affinity chromatography technology, pull down	Dias SS (2009), Dias SS (2009), Dias SS (2009)	3
YWHAZ	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
MDM2	2	XPO1	8	affinity chromatography technology	Jacob AG (2014)	1
MAPKAPK2	1	BCL2L1	0	enzymatic study	Wang J (2012)	1
STAT3	0	MAPKAPK2	1	two hybrid	Grossmann A (2015)	1
ATF1	0	CSNK2B	5	pull down	Yamaguchi Y (1998)	1
CUL3	17	HSPB1	2	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	DDX5	2	affinity chromatography technology	Okoro DR (2013)	1
CUL3	17	ELAVL1	0	affinity chromatography technology	Bennett EJ (2010)	1
AKT1	1	DDX5	2	affinity chromatography technology, affinity chromatography technology	Zhu QS (2011), Zhu QS (2011)	2
CUL3	17	PABPC1	5	affinity chromatography technology	Bennett EJ (2010)	1
MAPKAPK2	1	CDC25B	4	enzymatic study	Manke IA (2005)	1
MOV10	6	DES	1	affinity chromatography technology	Castello A (2012)	1
MAPKAPK2	1	ARPC5	2	pull down, enzymatic study, pull down	Singh S (2003), Singh S (2003), Singh S (2003)	3
ELAVL1	0	ZFP36L1	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CSNK2B	5	MAPKAPK2	1	protein complementation assay, affinity chromatography technology	Srivastav RK (2011), Srivastav RK (2011)	2
DDX5	2	HNRNPA0	1	biochemical, two hybrid, two hybrid	Havugimana PC (2012), Hegele A (2012), Hegele A (2012)	3
HNRNPL	3	ARPC5	2	affinity chromatography technology	Fei T (2017)	1
AKT1	1	MAPKAPK2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, imaging technique	Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Wu R (2007), Wu R (2007), Chen TC (2014)	7
ZFP36	2	PABPC1	5	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kedar VP (2010), Kedar VP (2010), Kedar VP (2010), Clement SL (2011)	4
ESR1	0	MDM2	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down	Liu G (2000), Kinyamu HK (2003), Duong V (2007), Duong V (2007), Duong V (2007), Duong V (2007), Saji S (2001), Saji S (2001)	8
MAPKAPK2	1	ALOX5	1	enzymatic study	Werz O (2002)	1
XPO1	8	PABPC1	5	affinity chromatography technology	Kirli K (2015)	1
COPS5	0	HNRNPA0	1	affinity chromatography technology	Bennett EJ (2010)	1
MAPK14	0	PHC2	3	protein complementation assay	Srivastav RK (2011)	1
COPS5	0	CHEK1	2	affinity chromatography technology	Bennett EJ (2010)	1
ESR1	0	PABPC1	5	affinity chromatography technology	Tarallo R (2011)	1
MAPK14	0	ETV1	1	enzymatic study	Janknecht R (2001)	1
ESR1	0	STAT3	0	affinity chromatography technology	Wang LH (2001)	1
ESR1	0	DDX5	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ambrosino C (2010), Ambrosino C (2010), Fujita T (2003), Mooney SM (2010), Tarallo R (2011), Mooney SM (2010)	6
ESR1	0	HSPB1	2	affinity chromatography technology, pull down	Kanaujiya JK (2013), Nalvarte I (2010)	2
AKT1	1	YWHAZ	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Powell DW (2002), Powell DW (2002), Powell DW (2002), Klein JB (2005)	4
MAPKAPK2	1	PABPC1	5	enzymatic study	Bollig F (2003)	1
MAPK14	0	MAPKAPK5	0	two hybrid	Bandyopadhyay S (2010)	1
ESR1	0	MAPK1	1	pull down, enzymatic study	Metivier R (2002), Tremblay A (2001)	2
MAPK14	0	MAPK3	4	affinity chromatography technology, protein complementation assay	Sanz-Moreno V (2003), Srivastav RK (2011)	2
CUL3	17	HNRNPL	3	affinity chromatography technology	Bennett EJ (2010)	1
HNRNPL	3	MAPKAPK2	1	affinity chromatography technology	Fei T (2017)	1
MOV10	6	YWHAZ	1	affinity chromatography technology	Castello A (2012)	1
COPS5	0	DDX5	2	affinity chromatography technology	Bennett EJ (2010)	1
MAPKAPK2	1	LSP1	3	enzymatic study	Huang CK (1997)	1
WASF1	10	MAPKAPK2	1	pull down	Singh S (2003)	1
MAPKAPK2	1	MDM2	2	enzymatic study	Weber HO (2005)	1
COPS5	0	HSPB1	2	affinity chromatography technology	Bennett EJ (2010)	1
ELAVL1	0	STAT3	0	affinity chromatography technology	Abdelmohsen K (2009)	1
XPO1	8	BECN1	2	affinity chromatography technology	Kirli K (2015)	1
MAPKAPK2	1	ZFP36L1	1	enzymatic study, enzymatic study	Benjamin D (2006), Maitra S (2008)	2
SHC1	0	ESR1	0	affinity chromatography technology, pull down	Song RX (2002), Song RX (2002)	2
MAP2K6	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
COPS5	0	MAPKAPK2	1	affinity chromatography technology	Bennett EJ (2010)	1
YWHAZ	1	MDM2	2	affinity chromatography technology	Zhang B (2017)	1