PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CUL3	17	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
CCNE1	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Harbour JW (1999), Manenti S (1999), Horton LE (1997), Higashi H (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999)	9
PTPA	0	CCT2	1	affinity chromatography technology	Glatter T (2009)	1
RASSF1	3	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
E2F4	0	RBL1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen CR (2002), Iavarone A (1999), Schmit F (2007), Moberg K (1996), Magae J (1996), Beijersbergen RL (1994), Ginsberg D (1994), Trimarchi JM (1998)	8
PRKAR1A	4	CCNE1	1	affinity chromatography technology	Gupte RS (2006)	1
BTRC	1	E2F1	0	enzymatic study	Ohta T (2001)	1
AKT1	1	TERT	7	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Kawauchi K (2005), Kim MO (2008), Ivanov AA (2017)	3
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
BTRC	1	RASSF1	3	two hybrid, affinity chromatography technology, bioid, affinity chromatography technology	Vinayagam A (2011), Zhou X (2012), Coyaud E (2015), Huttlin EL (2017)	4
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
CUL3	17	CDK4	2	affinity chromatography technology	Bennett EJ (2010)	1
FOXM1	3	GSK3B	1	affinity chromatography technology	Chen Y (2016)	1
MYC	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Gregory MA (2003), Gregory MA (2003), Arnold HK (2009), Zhou Z (2014)	4
AURKA	1	RASSF1	3	enzymatic study, fluorescent resonance energy transfe	Chow C (2011), Ivanov AA (2017)	2
CDKN2A	1	BRCA1	7	affinity chromatography technology, affinity chromatography technology, imaging technique	He L (2008), He L (2008), He L (2008)	3
KAT2A	1	HIST1H1B	4	enzymatic study	Brand M (1999)	1
FZR1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FOXM1	3	PRC1	4	affinity chromatography technology	Li X (2015)	1
CCNE1	1	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Shanahan F (1999), Connor MK (2003), Connor MK (2003), Jeon Y (2007), Bustany S (2011), Xu X (1999), Xu X (1999), Datta NS (1998), Orend G (1998), Liu J (1997), Sheaff RJ (1997), Sheaff RJ (1997), Bresnahan WA (1996), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Ciarallo S (2002), Ciarallo S (2002), Chu I (2007), Chu I (2007), Chen J (1996), Levkau B (1998), Larrea MD (2009), Grimmler M (2007), Chen TC (2014), Qiu H (2016)	26
AURKA	1	LATS2	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, fluorescent resonance energy transfe	Yabuta N (2011), Toji S (2004), Toji S (2004), Toji S (2004), Toji S (2004), Ivanov AA (2017)	6
CCNE1	1	E2F1	0	affinity chromatography technology	Dhillon NK (2002)	1
GRM1	4	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AURKA	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kwon YW (2012), Chou CH (2013), Chou CH (2013)	3
BRCA1	7	AR	3	pull down, pull down, two hybrid	Park JJ (2000), Yeh S (2000), Yeh S (2000)	3
CREBBP	29	SMARCB1	1	biochemical, affinity chromatography technology	Cho H (1998), Cho H (1998)	2
CREBBP	29	NFYB	2	affinity chromatography technology	Leclerc GJ (2010)	1
PRKN	1	NBN	1	affinity chromatography technology	Zhu X (2017)	1
CALM1	0	AKT1	1	pull down, affinity chromatography technology	Shen X (2005), Shen X (2005)	2
CDK2	0	RBL1	1	enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Leng X (2002), Zhao J (1998), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	8
CDK4	2	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Ivanov AA (2017)	2
CUL3	17	SMARCB1	1	affinity chromatography technology	Bennett EJ (2010)	1
PCNA	0	CDK5	0	affinity chromatography technology, affinity chromatography technology	Takasaki Y (2001), Wu SM (1998)	2
RASSF1	3	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Kehn K (2004), Kehn K (2004), Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017), Denicourt C (2008), Ivanov AA (2017)	8
FZR1	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC25A	2	CDK3	0	affinity chromatography technology	Li X (2016)	1
AKT1	1	AR	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017)	5
CDK2	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Youn CK (2005), Porter LA (2003), Law BK (2002), Connor MK (2003), Naderi S (2005), Varshochi R (2005), Hsu SP (2008), McAndrew CW (2007), Peiretti A (2003), Peiretti A (2003), Haddad MM (1999), Xu X (1999), Xu X (1999), Radu M (2008), Mori S (1999), Schulman BA (1998), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Sheaff RJ (1997), Vlach J (1996), Vlach J (1996), Vlach J (1997), Liu S (2009), Rosner M (2004), Ciarallo S (2002), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Chu I (2007), Chu I (2007), Levkau B (1998), Levkau B (1998), Lacy ER (2005), Zhao J (1998), Seo DW (2006), Kossatz U (2006), Grimmler M (2007), Grimmler M (2007), Varjosalo M (2013), Varjosalo M (2013), Montagnoli A (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Lovisa S (2016), Qiu H (2016), Carrasco-Garcia E (2011), Huttlin EL (2017), Hu B (2017)	52
BRCA1	7	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu Y (2012), Lu Y (2012), Parameswaran B (2015)	3
CDK2	0	RRN3	3	pull down	Mayer C (2004)	1
CCT2	1	CCNE1	1	affinity chromatography technology	Won KA (1998)	1
CDKN2C	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BRCA1	7	MYC	2	affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Li H (2002), Xiong J (2003), Xiong J (2003), Wang Q (1998), Wang Q (1998), Wang Q (1998), Harte MT (2010), Harte MT (2010), Xiong J (2003), Xiong J (2003), Zhou C (2003)	11
BRCA1	7	CCT2	1	affinity chromatography technology	Ertych N (2016)	1
CCNE1	1	AR	3	affinity chromatography technology	Yamamoto A (2000)	1
TERT	7	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1A	1	HIST1H1B	4	enzymatic study	Poon RY (1996)	1
GLIS2	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRM1	4	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CALM1	0	AR	3	affinity chromatography technology, pull down, imaging technique	Cifuentes E (2004), Cifuentes E (2004), Cifuentes E (2004)	3
FZR1	1	CDC25A	2	affinity chromatography technology, pull down, enzymatic study	Gao D (2009), Donzelli M (2002), Donzelli M (2002)	3
CDC6	0	CDKN2A	1	pull down	Ramachandran N (2004)	1
CDK7	0	CDK2	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Drapkin R (1996), Cheng A (2005), Xu X (1999), Higashi H (1996), Aprelikova O (1995), Moisan A (2004), Larochelle S (2012), Larochelle S (2006), Larochelle S (2006), Garrett S (2001), Garrett S (2001), Lolli G (2004), Varjosalo M (2013), So J (2015)	14
ARNT	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIN1	0	CDK2	0	pull down	Yeh ES (2006)	1
CUL4B	8	CDK4	2	affinity chromatography technology	Bennett EJ (2010)	1
GLIS2	2	CTNNB1	30	two hybrid, affinity chromatography technology, pull down	Kim YS (2007), Kim YS (2007), Kim YS (2007)	3
FOXM1	3	FBXW7	2	affinity chromatography technology	Chen Y (2016)	1
CCNE1	1	CETN1	0	biochemical	Matsumoto Y (2004)	1
CDKN1A	1	CKS2	0	affinity chromatography technology	Fogeron ML (2013)	1
PIN1	0	CCNE1	1	pull down, affinity chromatography technology	Yeh ES (2006), Yeh ES (2006)	2
MYC	2	KAT2A	1	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	McMahon SB (2000), Faiola F (2005), Liu X (2008), Conacci-Sorrell M (2010), Liu X (2003), Liu X (2003), Ivanov AA (2017)	7
CCNE1	1	SKP2	2	pull down, enzymatic study	Yeh KH (2001), Enchev RI (2012)	2
GLIS2	2	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NPAT	4	CDK2	0	pull down, enzymatic study, unspecified method, enzymatic study, affinity chromatography technology	Ma T (2000), Ma T (2000), Zhao J (1998), Zhao J (1998), Zhao J (1998)	5
AKT1	1	CREBBP	29	pull down, enzymatic study	Drendall CI (2010), Drendall CI (2010)	2
MYC	2	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTNNB1	30	CREBBP	29	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ma H (2005), Sustmann C (2008), Taurin S (2006), Zhao Y (2016), Benoit YD (2017)	5
LATS2	1	RASSF1	3	fluorescent resonance energy transfe, pull down, fluorescent resonance energy transfe	Mo XL (2015), Mo XL (2015), Ivanov AA (2017)	3
GRM1	4	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	TUBG1	2	biochemical	Matsumoto Y (2004)	1
CDK4	2	RBL1	1	enzymatic study	Anders L (2011)	1
AURKA	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXW7	2	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Thompson BJ (2007), Welcker M (2004), Welcker M (2004), Yada M (2004), Yada M (2004), Yada M (2004), Koch HB (2007), Kim BY (2010), Cho HJ (2010), Popov N (2007), Fujii M (2006), Yumimoto K (2012), Diefenbacher ME (2015), Kourtis N (2015), Kourtis N (2015), Li J (2017), Wang Y (2017), Reiterer V (2017), Chandra S (2013), Chandra S (2013), Chandra S (2013), Chandra S (2013)	22
RBL2	5	SMARCA4	19	two hybrid	Dunaief JL (2002)	1
CDKN1A	1	CDK4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Selma Dagtas A (2010), Guidoboni M (2005), Santiago FS (2007), Santiago FS (2007), Hsu SP (2008), Kehn K (2004), Kokontis JM (1998), Orend G (1998), Zheleva DI (2002), Mandal M (1998), Chen J (1996), Chen J (1996), Ramachandran N (2004), Gorospe M (1996), Fogeron ML (2013), Hukkelhoven E (2012), Hukkelhoven E (2012), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	20
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
SMARCA4	19	SMARCC1	5	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Sif S (2001), Wang W (1996), Otsuki T (2001), Zhao K (1998), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Inayoshi Y (2006), Inayoshi Y (2006), Pal S (2003), Pal S (2003), Bultman SJ (2005), Nagl NG (2005), Mahajan MC (2005), Trotter KW (2008), Dallas PB (1998), Tando T (2010), Tando T (2010), Bartlett C (2011), Bartlett C (2011), Oh J (2008), Oh J (2008), Havugimana PC (2012), Wan C (2015)	25
STK11	2	SMARCC1	5	affinity chromatography technology	Brajenovic M (2004)	1
CCNE1	1	SMARCA2	17	affinity chromatography technology	Shanahan F (1999)	1
CCND2	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sweeney KJ (1997), Huttlin EL (2015), Huttlin EL (2017)	3
SKP2	2	AR	3	imaging technique, affinity chromatography technology	Li B (2014), Li B (2014)	2
CREBBP	29	TP73	2	pull down, pull down	Zeng X (2000), Lemasson I (2001)	2
TP73	2	AURKA	1	affinity chromatography technology, enzymatic study, affinity chromatography technology	Katayama H (2012), Katayama H (2012), Katayama H (2012)	3
E2F1	0	CDK7	0	affinity chromatography technology	Vandel L (1999)	1
CDT1	2	CDK1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Huttlin EL (2017)	4
E2F1	0	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Lu H (2013), Lu H (2013)	2
CDK4	2	MYC	2	enzymatic study, two hybrid, fluorescent resonance energy transfe	Anders L (2011), Wang J (2011), Ivanov AA (2017)	3
CCND2	2	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL3	17	AURKA	1	affinity chromatography technology	Moghe S (2012)	1
SMARCA4	19	CTNNB1	30	affinity chromatography technology, two hybrid	Barker N (2001), Barker N (2001)	2
ARNT	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK3	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CREBBP	29	NPAT	4	affinity chromatography technology	Wang A (2004)	1
AURKA	1	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	NBN	1	affinity chromatography technology, affinity chromatography technology	Wu J (2012), Wu J (2012)	2
FGFR4	6	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AR	3	SMARCB1	1	bioid	Lempiaeinen JK (2017)	1
CDT1	2	CDC6	0	pull down, pull down, imaging technique	Sugimoto N (2008), Ramachandran N (2004), Sugimoto N (2015)	3
AURKA	1	BTRC	1	affinity chromatography technology	Irelan JT (2007)	1
TUBG1	2	CCT2	1	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Hein MY (2015)	2
MYC	2	POLD1	5	affinity chromatography technology	Koch HB (2007)	1
CDK2	0	H1F0	3	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Abbas T (2007), Zhang F (2007), He W (2003), Scholz A (2003), Peiretti A (2003), Zheleva DI (2002), Garcia-Morales P (2006), Kong Y (2009), Toji S (2004), Yang HY (2006)	10
CDC25A	2	CUL3	17	two hybrid	Wang J (2011)	1
MYC	2	SF3B1	12	two hybrid	Bandyopadhyay S (2010)	1
RASSF1	3	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	RBL1	1	affinity chromatography technology	Shanahan F (1999)	1
TERT	7	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BRCA1	7	ARNT	1	affinity chromatography technology, pull down, affinity chromatography technology	Kang HJ (2006), Kang HJ (2006), Kang HJ (2006)	3
BRCA1	7	MCM3	2	affinity chromatography technology	Ertych N (2016)	1
GSK3B	1	TSC1	4	affinity chromatography technology	Mak BC (2003)	1
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
CDK2	0	PRKAR1A	4	affinity chromatography technology, enzymatic study, affinity chromatography technology	Gupte RS (2006), Gupte RS (2006), Gupte RS (2006)	3
MYC	2	PRC1	4	genetic interference	Toyoshima M (2012)	1
AURKA	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTNNB1	30	FOXM1	3	affinity chromatography technology	Chen Y (2016)	1
RB1	2	AR	3	pull down, pull down, two hybrid, affinity chromatography technology	Lu J (1998), Yeh S (1998), Yeh S (1998), Gamble SC (2007)	4
UBC	7	E2F1	0	affinity chromatography technology	Rizos H (2007)	1
CKS2	0	CCNE1	1	affinity chromatography technology	Huttlin EL (2017)	1
STK11	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRM1	4	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TSC1	4	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIN1	0	CDKN1B	1	pull down, affinity chromatography technology, unspecified method	Zhou W (2009), Zhou W (2009), Zhou W (2009)	3
CDK1	0	HIST1H1A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Zhan Q (1999), Horton LE (1997), Pan ZQ (1993), Pan ZQ (1993), Yarden RI (2002), Golsteyn RM (1995), Jiang W (1998), Badea T (2002), Bae Y (2013), Linares JF (2011), Sasaki T (2008), Chen M (2012), Tang J (2008)	13
UHRF2	1	PIN1	0	affinity chromatography technology	Lai M (2016)	1
CDK3	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDK4	2	CDKN2A	1	affinity chromatography technology, unspecified method, pull down, two hybrid, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, two hybrid, pull down, two hybrid, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Fahraeus R (1996), Li J (2004), Sugimoto M (1999), Serrano M (1993), Serrano M (1993), Serrano M (1993), Coleman KG (1997), Zhang Y (1998), Haddad MM (1999), Li J (2002), Li J (2002), Lal G (2000), Yarbrough WG (1999), Della Torre G (2001), Jones R (2007), Jones R (2007), Ramachandran N (2004), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Fei HJ (2017), Huttlin EL (2017), Ivanov AA (2017)	25
CDKN2A	1	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Herkert B (2010), Amente S (2007), Zhang Q (2013), Ivanov AA (2017)	4
CUL3	17	SF3B1	12	affinity chromatography technology	Bennett EJ (2010)	1
FZR1	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	HIST1H1A	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Jeon Y (2007), Lunn CL (2010), Kiviharju-af Haellstroem TM (2007), Kim YB (2000), Xu X (1999), Mori S (1999), Lauper N (1998), Lauper N (1998), Orend G (1998), Wu G (1997), Horton LE (1997), Higashi H (1996), Musgrove EA (1996), Pan ZQ (1993), Pan ZQ (1993), Poon RY (1993), Sueoka N (1999), Baldassarre G (2000), Bendjennat M (2003), Liu S (2009), Sarmento LM (2005), Aprelikova O (1995), Giono LE (2007), Liu Y (2004), Dynlacht BD (1997), Mandal M (1998), Chang TS (2003), Colas P (1996), Jiang W (1998), Ezhevsky SA (1997), Thomas DM (2004), Song MS (2011), Naderi S (1999), Akagi M (1996), Lee B (2006), Grimmler M (2007), Zhang WN (2013), Iyer NG (2007), Morris L (2000), Chen M (2012), Guidoboni M (2005), Ghiani C (2001)	42
CDK6	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CALM1	0	CCND2	2	pull down	Chen BB (2012)	1
ARNT	1	CDKN2C	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	E2F1	0	affinity chromatography technology, pull down	Eymin B (2001), Eymin B (2001)	2
FZR1	1	PRKN	1	affinity chromatography technology, affinity chromatography technology	Lee SB (2015), Lee SB (2015)	2
LATS2	1	CDKN1A	1	enzymatic study	Suzuki H (2013)	1
RRN3	3	UBTF	8	affinity chromatography technology	Miller G (2001)	1
AKAP9	13	CALM1	0	affinity chromatography technology, pull down	Takahashi M (2002), Takahashi M (2002)	2
UBC	7	CDKN1B	1	affinity chromatography technology	Huang G (2014)	1
CDK6	0	FOXM1	3	enzymatic study	Anders L (2011)	1
CDK4	2	UBTF	8	enzymatic study	Voit R (1999)	1
TERT	7	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	UBTF	8	enzymatic study	Voit R (1999)	1
STK11	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	CDK3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FBXW7	2	GSK3B	1	affinity chromatography technology	Kwon YW (2012)	1
MYC	2	CCT2	1	affinity chromatography technology	Koch HB (2007)	1
AKT1	1	GSK3B	1	pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016)	16
AURKA	1	CTNNB1	30	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	CDK1	0	pull down	Wang H (1997)	1
FOXM1	3	MYBL2	2	affinity chromatography technology	Li X (2015)	1
FZR1	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC6	0	CDK2	0	affinity chromatography technology, enzymatic study	Saha P (1998), Jiang W (1999)	2
BTRC	1	CCT2	1	bioid	Coyaud E (2015)	1
CDT1	2	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2008), Senga T (2006), Hu J (2006), Arias EE (2006), Nishitani H (2006), Tsanov N (2014), Chandrasekaran S (2011), Coleman KE (2015), Higa LA (2006)	11
CUL3	17	POLD1	5	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
CDK7	0	HIST1H1A	0	enzymatic study	Drapkin R (1996)	1
FZR1	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	SMARCA4	19	two hybrid, affinity chromatography technology	Becker TM (2009), Becker TM (2009)	2
CDK1	0	TSC1	4	pull down	Astrinidis A (2003)	1
CDK4	2	CDC6	0	enzymatic study	Anders L (2011)	1
CDKN1A	1	CDK5	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013)	4
CDKN2B	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	LATS2	1	enzymatic study	Toji S (2004)	1
POLA1	0	PCNA	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
PSMA6	1	CDK4	2	affinity chromatography technology	Sharma SS (2011)	1
RBL2	5	SKP2	2	affinity chromatography technology, enzymatic study	Bhattacharya S (2003), Tedesco D (2002)	2
GLIS2	2	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BRCA1	7	SMARCA2	17	affinity chromatography technology, affinity chromatography technology	Hill DA (2004), Fontana GA (2017)	2
CDK3	0	CKS2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KAT2A	1	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS2	0	CDKN1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CCNE1	1	CDK4	2	affinity chromatography technology, fluorescent resonance energy transfe	Datta NS (1998), Ivanov AA (2017)	2
LATS2	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	HIST1H1A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Kim YB (2000), Sueoka N (1999), Mandal M (1998), Iyer NG (2007)	4
FGFR4	6	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	PIN1	0	affinity chromatography technology, affinity chromatography technology	Arnold HK (2009), Yeh E (2004)	2
KAT2A	1	CDK2	0	enzymatic study	Mateo F (2009)	1
GRM1	4	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AR	3	E2F1	0	affinity chromatography technology, affinity chromatography technology	Li Y (2012), Li Y (2012)	2
CCNE1	1	TP73	2	enzymatic study, pull down	Gaiddon C (2003), Gaiddon C (2003)	2
CDKN1B	1	CDK6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Radu M (2008), Bockstaele L (2006), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	6
CCNE1	1	POLD1	5	enzymatic study, affinity chromatography technology	Wu SM (1998), Wu SM (1998)	2
UBC	7	PSMA6	1	affinity chromatography technology	Matsumoto M (2005)	1
SKP2	2	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study	Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Lin HK (2009), Roe JS (2011), Gao D (2009), Gao D (2009), Chan CH (2013)	9
CUL3	17	SMARCC1	5	affinity chromatography technology	Bennett EJ (2010)	1
CDK4	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Serrano M (1993), Xiong Y (1993), Takasaki Y (2001)	3
GRM1	4	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDT1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Li X (2003), Li X (2003), Sugimoto N (2008), Liu E (2004), Liu E (2004), Sugimoto N (2004), Takeda DY (2005), Hein MY (2015)	9
GLIS2	2	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2C	0	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK3	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
AR	3	LATS2	1	two hybrid, affinity chromatography technology	Powzaniuk M (2004), Powzaniuk M (2004)	2
CDKN1B	1	CDK5	0	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Kabuta T (2013), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	7
UHRF2	1	CDK6	0	far western blotting	Mori T (2011)	1
AR	3	RBL1	1	affinity chromatography technology	Su S (2013)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
TP73	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Uramoto H (2002), Uramoto H (2002), Uramoto H (2002), Watanabe K (2002), Watanabe K (2002)	5
CDK2	0	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CDK7	0	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
RASSF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC6	0	CDKN1A	1	pull down, imaging technique	Ramachandran N (2004), Chen TC (2014)	2
PRKN	1	HERC5	2	affinity chromatography technology, affinity chromatography technology	Im E (2016), Im E (2016)	2
MYBL2	2	CREBBP	29	genetic interference, affinity chromatography technology, affinity chromatography technology	Bessa M (2001), Bessa M (2001), Kurahashi T (2005)	3
SKP2	2	RASSF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song MS (2008), Song MS (2008), Calvisi DF (2009)	3
CCNE1	1	MARCKS	0	enzymatic study	Manenti S (1999)	1
FZR1	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CREBBP	29	CDKN1A	1	affinity chromatography technology, imaging technique	Fritah A (2005), Chen TC (2014)	2
CCNE1	1	MYBL2	2	enzymatic study	Johnson TK (1999)	1
GSK3B	1	CCNE1	1	enzymatic study, imaging technique	Welcker M (2003), Chen TC (2014)	2
CDC6	0	MYC	2	pull down	Takayama M (2000)	1
NF2	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	HERC5	2	affinity chromatography technology, pull down	Mitsui K (1999), Mitsui K (1999)	2
UBC	7	CISH	1	affinity chromatography technology, affinity chromatography technology	Jensik PJ (2015), Jensik PJ (2015)	2
RBL1	1	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dyson N (1993), Dyson N (1993), Moberg K (1996), Dhillon NK (2002), Su S (2013), Trimarchi JM (1998)	6
UHRF2	1	CUL4B	8	affinity chromatography technology	Lai M (2016)	1
CDK2	0	CUL4B	8	affinity chromatography technology	Neganova I (2011)	1
CDKN2C	0	CDK4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Ewing RM (2007), Guan KL (1994), Guan KL (1994), Guan KL (1994), Li J (2002), Wang J (2011), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017), Ivanov AA (2017)	13
CDC6	0	FZR1	1	pull down, enzymatic study, enzymatic study	Ke PY (2004), Petersen BO (2000), Cotto-Rios XM (2011)	3
NBN	1	TUBG1	2	biochemical, affinity chromatography technology	Shimada M (2009), Shimada M (2009)	2
FBXW7	2	CCNE1	1	enzymatic study, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, pull down, unspecified method, enzymatic study, affinity chromatography technology	Welcker M (2003), Thompson BJ (2007), Hao B (2007), Hao B (2007), van Drogen F (2006), Minella AC (2005), Busino L (2012), Ye X (2004), Ye X (2004), Grim JE (2008), Jin J (2005), Welcker M (2007), Strohmaier H (2001), Strohmaier H (2001), Strohmaier H (2001), Welcker M (2013), Welcker M (2013), Pashkova N (2010), Pashkova N (2010), Nateri AS (2004), Pierce NW (2009), Wang Y (2017)	22
BTRC	1	CCNE1	1	enzymatic study, enzymatic study	Saha A (2008), Pierce NW (2013)	2
CDK6	0	AR	3	imaging technique	Chen TC (2014)	1
CCNE1	1	NBN	1	affinity chromatography technology	Stewart GS (2003)	1
GLIS2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2C	0	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RBL1	1	MYBL2	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Joaquin M (2003), Joaquin M (2002), Joaquin M (2002), Schmit F (2007)	4
CDK6	0	RBL2	5	enzymatic study	Anders L (2011)	1
NF2	1	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARID4A	3	CCNE1	1	enzymatic study	Suryadinata R (2011)	1
MYC	2	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TSC1	4	AKT1	1	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Roux PP (2004), Dan HC (2002), Ivanov AA (2017)	3
FBXW7	2	AURKA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Otto T (2009), Kwon YW (2012), Kwon YW (2012), Wang Y (2017)	4
BRCA1	7	SMARCC1	5	biochemical, affinity chromatography technology	Bochar DA (2000), Ertych N (2016)	2
CTNNB1	30	GSK3B	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davies G (2001), Kishida S (1999), Fischer L (2002), Kitagawa M (1999), Hart M (1999), Su Y (2008), Huang X (2009), Ding Q (2005), Piao S (2008), Varjosalo M (2013), Gao C (2014), Koo J (2015), Chen TC (2014), Lu D (2012), Kuslansky Y (2016), Novellasdemunt L (2017), Lu WJ (2015)	17
CUL3	17	CCT2	1	affinity chromatography technology	Bennett EJ (2010)	1
GLIS2	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BRCA1	7	MRE11	3	biochemical, pull down, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Paull TT (2001), Chiba N (2001), Chiba N (2001), Zhong Q (1999), Greenberg RA (2006), Zhao GY (2007), Hill SJ (2014), Suhasini AN (2013)	9
CDKN2A	1	CCND2	2	pull down, pull down, fluorescent resonance energy transfe	Li J (2004), Li J (2002), Ivanov AA (2017)	3
MCM3	2	CCNE1	1	affinity chromatography technology, pull down	Li J (2011), Li J (2011)	2
GLIS2	2	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	CTNNB1	30	enzymatic study, enzymatic study	Tian Q (2004), Fang D (2007)	2
PRKN	1	CCND2	2	affinity chromatography technology	Gong Y (2014)	1
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
CDK2	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koundrioukoff S (2000), Zhang H (1993), Neganova I (2011), Wu SM (1998), Chen Z (2002), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
PCNA	0	POLD1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology	Ohta S (2002), Naryzhny SN (2005), Naryzhny SN (2004), Ogi T (2010), Shikata K (2001), Shikata K (2001), Xie B (2002), Li H (2006), Park JM (2014), Han J (2014), Hein MY (2015)	11
CALM1	0	CETN1	0	biochemical	Tsang WY (2006)	1
CDK6	0	MYC	2	enzymatic study, fluorescent resonance energy transfe	Anders L (2011), Ivanov AA (2017)	2
FZR1	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDKN1A	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	McKenzie PP (2003), McKenzie PP (2003), Jeon Y (2007), Derjuga A (2001), Datta NS (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bresnahan WA (1996), Bendjennat M (2003), Bao GC (2006), Chen J (1996), Chen J (1996), Chen J (1996), Levkau B (1998), Poon RY (1996), Zhao J (1998), Wang J (2011), Fogeron ML (2013), Chen TC (2014)	20
GSK3B	1	AR	3	pull down, affinity chromatography technology	Wang L (2004), Wang L (2004)	2
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
UHRF2	1	CDK2	0	far western blotting, affinity chromatography technology, enzymatic study	Mori T (2011), Li Y (2004), Li Y (2004)	3
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
PIN1	0	TP73	2	affinity chromatography technology, pull down	Mantovani F (2004), Mantovani F (2004)	2
CDK2	0	POLD1	5	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Wu SM (1998), Wu SM (1998), Wu SM (1998), Wu SM (1998)	4
FZR1	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2017)	2
UBC	7	PRKAR1A	4	affinity chromatography technology	Matsumoto M (2005)	1
CDKN2A	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
POLA1	0	MCM3	2	biochemical	Havugimana PC (2012)	1
MYC	2	RBL1	1	affinity chromatography technology	Beijersbergen RL (1994)	1
CDKN2C	0	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	CDKN1A	1	pull down, enzymatic study, imaging technique, enzymatic study	Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001)	4
CDK2	0	CDK6	0	biochemical, imaging technique	Cheng A (2000), Chen TC (2014)	2
CTNNB1	30	PRKN	1	affinity chromatography technology, affinity chromatography technology	Lin DC (2015), Lin DC (2015)	2
FBXW7	2	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	Jiang JX (2016), Jiang JX (2016)	2
GRM1	4	CDKN2C	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	CTNNB1	30	bioid, affinity chromatography technology, affinity chromatography technology, pull down	Couzens AL (2013), Li J (2013), Li J (2013), Li J (2013)	4
RASSF1	3	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	PRC1	4	enzymatic study	Jiang W (1998)	1
TSC1	4	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	RBL2	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CCNE1	1	CDC25A	2	affinity chromatography technology, pull down	Shanahan F (1999), Xu X (1996)	2
FZR1	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	H1F0	3	enzymatic study, enzymatic study, enzymatic study	Kim KS (2002), Toji S (2004), Goss VL (1994)	3
ARID4A	3	CDK2	0	enzymatic study	Suryadinata R (2011)	1
CCNE1	1	H1F0	3	enzymatic study	Abbas T (2007)	1
PTPA	0	AKT1	1	enzymatic study, enzymatic study	Ma Y (2007), Li L (2003)	2
STK11	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2017)	3
BRCA1	7	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Li H (2010), Li H (2010), Li H (2010), Ertych N (2016)	4
UHRF2	1	MRE11	3	affinity chromatography technology	Lai M (2016)	1
AR	3	SMARCA4	19	affinity chromatography technology, two hybrid, affinity chromatography technology, bioid	Wang Q (2004), van de Wijngaart DJ (2009), Dai Y (2008), Lempiaeinen JK (2017)	4
CCNE1	1	MRE11	3	affinity chromatography technology	Stewart GS (2003)	1
SKP2	2	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), von der Lehr N (2003), Zhang Q (2013), Kim TA (2013), Jamal A (2015), Fujii M (2006)	9
CDT1	2	CDK4	2	affinity chromatography technology	Liu E (2004)	1
STK11	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Moorthamer M (1999), Sweeney KJ (1997), Jiang W (1998), Welcker M (1998)	4
UBC	7	MRE11	3	affinity chromatography technology	Matsumoto M (2005)	1
CCNE1	1	SF3B1	12	affinity chromatography technology	Shanahan F (1999)	1
CDKN2A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
UHRF2	1	PCNA	0	far western blotting, x-ray crystallography, unspecified method, affinity chromatography technology	Mori T (2011), Chen W (2017), Chen W (2017), Lai M (2016)	4
FZR1	1	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS2	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK3	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CETN1	0	BRCA1	7	imaging technique	Tarapore P (2012)	1
NF2	1	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL3	17	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Bish RA (2007), Wu K (2016)	4
RASSF1	3	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1B	1	HIST1H1B	4	enzymatic study	McAndrew CW (2007)	1
HIST1H1A	0	SF3B1	12	affinity chromatography technology	Huttlin EL (2015)	1
CCNE1	1	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Wong AK (2000), Shanahan F (1999)	2
CDKN2C	0	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GRM1	4	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL3	17	SMARCA4	19	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Major ML (2004)	2
NFYB	2	MYC	2	affinity chromatography technology, pull down	Izumi H (2001), Izumi H (2001)	2
GLIS2	2	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARID4A	3	CDK4	2	enzymatic study	Suryadinata R (2011)	1
CDT1	2	CCNE1	1	affinity chromatography technology	Liu E (2004)	1
BTRC	1	PRKAR1A	4	affinity chromatography technology	Coyaud E (2015)	1
CDK2	0	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	McAndrew CW (2007), Hale TK (2006), Deep G (2006), Cheng A (2005), Alexandrow MG (2005), Nishimura T (2005), Du J (2004), Matsumoto Y (2004), Kehn K (2004), Harwell RM (2004), Shen WH (2004), Contreras A (2003), Porter LA (2002), Esashi F (2005), Dehde S (2001)	15
CCNE1	1	SMARCB1	1	affinity chromatography technology	Shanahan F (1999)	1
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
CTNNB1	30	CCNE1	1	pull down, affinity chromatography technology, affinity chromatography technology	Park CS (2004), Park CS (2004), Park CS (2004)	3
MCM3	2	CDK2	0	affinity chromatography technology, pull down, pull down	Li J (2011), Li J (2011), Ramachandran N (2004)	3
CTNNB1	30	CDK2	0	pull down, affinity chromatography technology	Park CS (2004), Park CS (2004)	2
MYC	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
CDK1	0	CKS2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Varjosalo M (2013), Radulovic M (2010), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
PRKN	1	TUBG1	2	affinity chromatography technology, affinity chromatography technology	Hampe C (2006), Zhao J (2003)	2
CDK1	0	MARCKS	0	enzymatic study	Manenti S (1999)	1
NF2	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK3	0	CDT1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CCNE1	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PIN1	0	FBXW7	2	affinity chromatography technology, affinity chromatography technology	Min SH (2012), Kourtis N (2015)	2
CUL3	17	PRKAR1A	4	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	TUBG1	2	affinity chromatography technology	Koch HB (2007)	1
GLIS2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	CCT2	1	affinity chromatography technology	Neganova I (2011)	1
ARHGEF5	3	CCNE1	1	two hybrid	Wang J (2011)	1
SMARCB1	1	AKT1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down	Foster KS (2006), Foster KS (2006), Foster KS (2006), Foster KS (2006)	4
CDK4	2	CDKN2B	0	two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Rual JF (2005), Stelzl U (2005), Vinayagam A (2011), Xin X (2009), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Ivanov AA (2017)	12
CDK6	0	RBL1	1	enzymatic study	Anders L (2011)	1
CDK4	2	FOXM1	3	enzymatic study	Anders L (2011)	1
BRCA1	7	RBL1	1	imaging technique, pull down	Fan S (2001), Fan S (2001)	2
NF2	1	CDK5	0	affinity chromatography technology	Zhou L (2015)	1
BRCA1	7	PSMA6	1	two hybrid	Woods NT (2012)	1
RASSF1	3	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS1B	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
RB1	2	UBTF	8	affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology	Hannan KM (2000), Hannan KM (2000), Hannan KM (2000), Hannan KM (2000), Cavanaugh AH (1995), Cavanaugh AH (1995)	6
SMARCA2	17	CREBBP	29	affinity chromatography technology	Zhang Y (2010)	1
CDK2	0	UBTF	8	enzymatic study	Voit R (1999)	1
AKT1	1	CDKN1B	1	enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology	Fujita N (2002), Fujita N (2002), Nacusi LP (2006), Chen TC (2014), Zhang H (2017), Zhang H (2017)	6
CDK4	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL3	17	CTNNB1	30	affinity chromatography technology	Bennett EJ (2010)	1
CDK4	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SMARCA2	17	SMARCC1	5	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Sif S (2001), Wang W (1996), Hu K (2006), Hu K (2006), Inayoshi Y (2006), Inayoshi Y (2006), Pal S (2003), Pal S (2003), Nagl NG (2005), Nakamura T (2002), Tando T (2010), Tando T (2010), Havugimana PC (2012), Wan C (2015)	14
PSMA6	1	CDK2	0	affinity chromatography technology, affinity chromatography technology	Sharma SS (2011), Neganova I (2011)	2
CREBBP	29	PCNA	0	affinity chromatography technology, pull down, enzymatic study	Cazzalini O (2014), Cazzalini O (2014), Cazzalini O (2014)	3
PSMA6	1	CCNE1	1	affinity chromatography technology	Sharma SS (2011)	1
CDK6	0	HIST1H1A	0	enzymatic study, enzymatic study	Jiang W (1998), Iyer NG (2007)	2
PRKN	1	AURKA	1	affinity chromatography technology	Lee SB (2015)	1
UBC	7	CCNE1	1	affinity chromatography technology	Huang G (2014)	1
CUL4B	8	CDT1	2	affinity chromatography technology	Higa LA (2003)	1
CDK4	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nair JS (2009), Takaki T (2004), Deep G (2006), Kehn K (2004), Scholz A (2003), Gladden AB (2003), Mori S (1999), Higashi H (1996), Musgrove EA (1996), Sarmento LM (2005), Kim KS (2002), Li J (2002), Garcia-Morales P (2006), Tsai CH (2009), Miralem T (2003), Toji S (2004), Halder SK (2005), Dynlacht BD (1997), Mandal M (1998), Voit R (1999), Annicotte JS (2006), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Kitagawa M (1996), Anders L (2011), Gaiddon C (2003), Seo DW (2006), Kabuta T (2013), Lee B (2006), Kossatz U (2006), Zarkowska T (1997), Nakanishi M (1999), Iyer NG (2007), Guidoboni M (2005), Barbash O (2009), Wang C (2001), Denicourt C (2008), Pan W (2001)	39
BRCA1	7	RBL2	5	imaging technique, pull down	Fan S (2001), Fan S (2001)	2
CCNE1	1	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Luescher-Firzlaff JM (2006)	2
SKP2	2	MYBL2	2	affinity chromatography technology	Charrasse S (2000)	1
AR	3	SMARCA2	17	two hybrid, affinity chromatography technology, bioid	van de Wijngaart DJ (2009), Dai Y (2008), Lempiaeinen JK (2017)	3
KAT2A	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FBXW7	2	CDK2	0	affinity chromatography technology, affinity chromatography technology	Zhang W (2012), Zhang W (2012)	2
CCND2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	CDKN2C	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS1B	0	CCNE1	1	affinity chromatography technology	Huttlin EL (2017)	1
RASSF1	3	GLIS2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARNT	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	KLF10	1	enzymatic study	Anders L (2011)	1
CDK4	2	H1F0	3	enzymatic study	Zheleva DI (2002)	1
CDKN2B	0	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
POLD1	5	MCM3	2	biochemical	Havugimana PC (2012)	1
HERC5	2	CDKN1A	1	pull down	Mitsui K (1999)	1
RASSF1	3	GRM1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARID4A	3	CDK1	0	enzymatic study	Suryadinata R (2011)	1
RBL2	5	RBL1	1	affinity chromatography technology	Litovchick L (2007)	1
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
CDK5	0	H1F0	3	enzymatic study	He W (2003)	1
CTNNB1	30	AR	3	pull down, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yang F (2002), Yang F (2002), Masiello D (2004), Song LN (2004), Amir AL (2003), Amir AL (2003), Mulholland DJ (2003), Mulholland DJ (2003), Pawlowski JE (2002), Mulholland DJ (2003), Levy L (2004)	11
CDK1	0	CDC6	0	enzymatic study	Jiang W (1999)	1
SMARCA4	19	RASSF1	3	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AKT1	1	SMARCC1	5	affinity chromatography technology, enzymatic study, pull down	Foster KS (2006), Foster KS (2006), Foster KS (2006)	3
CDC25A	2	CDK2	0	pull down, enzymatic study, affinity chromatography technology	Xu X (1996), Cheng A (2005), Li X (2016)	3
CDKN2A	1	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	SMARCA2	17	pull down	Pal S (2003)	1
TSC1	4	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UHRF2	1	CDK4	2	far western blotting	Mori T (2011)	1
BRCA1	7	CDK4	2	pull down, enzymatic study, enzymatic study	Wang H (1997), Kehn K (2007), Miralem T (2003)	3
AR	3	CDK7	0	affinity chromatography technology, pull down, pull down, enzymatic study	Lee DK (2000), Lee DK (2000), Chymkowitch P (2011), Chymkowitch P (2011)	4
CDKN2C	0	CDK6	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, x-ray crystallography, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ewing RM (2007), Guan KL (1994), Guan KL (1994), Guan KL (1994), Jeffrey PD (2000), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017), Venkataramani RN (2002), Ivanov AA (2017)	11
CDK6	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Garcia-Morales P (2006), Aprelikova O (1995), Yarbrough WG (1999), Dynlacht BD (1997), Jiang W (1998), Anders L (2011), Nakanishi M (1999), Iyer NG (2007)	8
CDKN2B	0	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	FOXM1	3	affinity chromatography technology, enzymatic study	Major ML (2004), Luescher-Firzlaff JM (2006)	2
LATS2	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARNT	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	SMARCC1	5	pull down, affinity chromatography technology	Pal S (2003), Koch HB (2007)	2
CDK1	0	E2F1	0	enzymatic study	Dynlacht BD (1997)	1
UBC	7	CDK7	0	imaging technique	Zhang X (2017)	1
AURKA	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	FZR1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	CDK1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Koff A (1992), Koff A (1992), Horton LE (1997)	4
CDKN2A	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RBL2	5	E2F1	0	affinity chromatography technology	Dhillon NK (2002)	1
KAT2A	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nishimura T (2005), Matsumoto Y (2004), Delk NA (2009), Poon RY (1996)	4
CDT1	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu E (2004), Sugimoto N (2004), Sugimoto N (2004), Takeda DY (2005), Varjosalo M (2013), Hein MY (2015)	6
CUL4B	8	PCNA	0	affinity chromatography technology	Banks D (2006)	1
BRCA1	7	TUBG1	2	imaging technique, affinity chromatography technology, pull down, biochemical, imaging technique, affinity chromatography technology, enzymatic study, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down	Hsu LC (2001), Hsu LC (2001), Hsu LC (2001), Hsu LC (1998), Hsu LC (1998), Hsu LC (1998), Starita LM (2004), Brodie KM (2012), Tarapore P (2012), Tarapore P (2012), Tarapore P (2012), Matsuzawa A (2014)	12
CDK5	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
GRM1	4	MYC	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BRCA1	7	CCNE1	1	affinity chromatography technology	Matsuoka S (2007)	1
SMARCB1	1	BRCA1	7	biochemical, biochemical, affinity chromatography technology	Bochar DA (2000), Bochar DA (2000), Fontana GA (2017)	3
CDKN1A	1	CDKN1B	1	genetic interference, imaging technique	Hsu SP (2008), Chen TC (2014)	2
CTNNB1	30	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, protein complementation assay, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, enzymatic study, protein complementation assay, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang J (2006), Yang J (2006), Cong F (2003), Kitagawa M (1999), Kitagawa M (1999), Kitagawa M (1999), Hart M (1999), Hart M (1999), Hart M (1999), Su Y (2008), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Liu J (2004), Dorrello NV (2006), Godin JD (2010), Guardavaccaro D (2008), Evrard-Todeschi N (2008), Saha A (2008), Saha A (2008), Chen CH (2012), Wei S (2008), Dehan E (2009), Wang D (2011), Gao D (2011), Li VS (2012), Sahasrabuddhe AA (2014), Mbom BC (2014), Mbom BC (2014), Kovacev J (2014), Gao C (2014), Kluge SF (2013), Chong RA (2014), Herrero-Ruiz J (2014), Zhang L (2012), Coyaud E (2015), Loveless TB (2015), Low TY (2014), Coyaud E (2015), Tseng RC (2015), Wu K (2016), Villalobos V (2010), Pierce NW (2009), Shrestha H (2016), Gu JJ (2016), Vaid M (2011)	46
MYC	2	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe	Ewing RM (2007), Park J (2002), Pal S (2003), Ivanov AA (2017)	4
CDK6	0	CDC6	0	enzymatic study	Anders L (2011)	1
E2F1	0	KAT2A	1	affinity chromatography technology	Lang SE (2001)	1
PRKN	1	CDK5	0	affinity chromatography technology, enzymatic study	Avraham E (2007), Avraham E (2007)	2
CDK4	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	HIST1H1A	0	enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Xu X (1999), Lauper N (1998), Lauper N (1998), Sharma SS (2011), Orend G (1998), Wu G (1997), Horton LE (1997), Higashi H (1996), Ciarallo S (2002), Jiang W (1998), Naderi S (1999), Ghiani C (2001)	12
CDK6	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang J (2012), Cataldo F (2013), Maestre C (2008), Maestre C (2008)	4
ARNT	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL4B	8	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Nathan JA (2013)	2
GLIS2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1A	1	PCNA	0	two hybrid, pull down, pull down, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Frouin I (2003), Watanabe H (1998), Fotedar R (1996), Jonsson ZO (1998), Gulbis JM (1996), Touitou R (2001), Yu P (2001), Yu P (2001), Chen X (2007), Chen X (2007), Wang SC (2006), Carujo S (2006), Garcia-Wilson E (2005), Howlett NG (2009), Jin Y (2008), Lee JY (2009), Ando T (2001), Ando T (2001), Takasaki Y (2001), Logette E (2011), Mistafa O (2010), Mistafa O (2010), Bruning JB (2004), Punchihewa C (2012), Mattock H (2001), Waga S (1994), Waga S (1994), Poon RY (1996), Zhang Y (1999), Warbrick E (1995), Warbrick E (1995), Poon RY (1998), Poon RY (1998), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Rizzardi LF (2014), Trombetta A (2013), Trombetta A (2013), Kim DH (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Coleman KE (2015), Huttlin EL (2017), Roessig L (2001), Roessig L (2001)	48
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
RB1	2	ARNT	1	affinity chromatography technology	Ge NL (1998)	1
E2F1	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Budhavarapu VN (2012), Budhavarapu VN (2012), Budhavarapu VN (2012), Singh RK (2017)	4
BRCA1	7	E2F1	0	affinity chromatography technology	Gorski JJ (2011)	1
CDKN2C	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FZR1	1	FOXM1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Park HJ (2008), Myatt SS (2013), Laoukili J (2008), Laoukili J (2008)	4
MYC	2	CDK2	0	genetic interference, genetic interference	Toyoshima M (2012), Zhou Z (2014)	2
GRM1	4	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Lin J (2001), Sweeney KJ (1997), Varjosalo M (2013), Ivanov AA (2017)	4
KAT2A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK7	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CTNNB1	30	PIN1	0	pull down	Ryo A (2001)	1
ARNT	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KAT2A	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	CTNNB1	30	imaging technique	Chen TC (2014)	1
ARNT	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	RRN3	3	pull down	Mayer C (2004)	1
E2F4	0	AR	3	affinity chromatography technology, affinity chromatography technology	Li Y (2012), Li Y (2012)	2
CCNE1	1	CALM1	0	affinity chromatography technology	Hui S (2011)	1
BTRC	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014), Herrero-Ruiz J (2014)	4
GLIS2	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	E2F4	0	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fajas L (2000), Iavarone A (1999), Moberg K (1996), Ezhevsky SA (1997), Ginsberg D (1994), Trimarchi JM (1998)	6
SMARCC1	5	MRE11	3	biochemical	Wan C (2015)	1
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
PRKN	1	MARCKS	0	affinity chromatography technology	Zanon A (2013)	1
SMARCA4	19	CREBBP	29	genetic interference	DiRenzo J (2000)	1
ARNT	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBC	7	CDKN2A	1	pull down, imaging technique	Zhang X (2017), Zhang X (2017)	2
RB1	2	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
CUL3	17	CUL4B	8	affinity chromatography technology	Bennett EJ (2010)	1
RBL1	1	SMARCA4	19	two hybrid	Dunaief JL (2002)	1
CCNE1	1	E2F4	0	affinity chromatography technology	Shanahan F (1999)	1
CDK7	0	CDKN1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CREBBP	29	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Pao GM (2000), Pao GM (2000), Benezra M (2003), Fan S (2002), Fan S (2002), Neish AS (1998), Nakuci E (2006), Crowe DL (2006), Chai YL (1999)	9
CDK2	0	TP73	2	enzymatic study	Gaiddon C (2003)	1
UHRF2	1	CDK1	0	far western blotting	Mori T (2011)	1
CDC6	0	MCM3	2	affinity chromatography technology, biochemical, pull down	Fujita M (1999), Mendez J (2000), Ramachandran N (2004)	3
PTPA	0	CCNE1	1	enzymatic study	Davis RJ (2017)	1
CCNE1	1	RBL2	5	affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Li Y (1993)	2
NF2	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
STK11	2	SMARCA4	19	pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Marignani PA (2001), Marignani PA (2001), Brajenovic M (2004), Ivanov AA (2017)	4
NBN	1	MRE11	3	biochemical, affinity chromatography technology, biochemical, two hybrid, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Cerosaletti KM (2003), Trujillo KM (1998), Matsuzaki K (2008), Desai-Mehta A (2001), Desai-Mehta A (2001), Desai-Mehta A (2001), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Nakanishi K (2002), Shimada M (2009), Shimada M (2009), Yanagihara H (2011), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Alt JR (2005), Havugimana PC (2012), Wijnhoven P (2015), Suhasini AN (2013), Suhasini AN (2013), Nicholson J (2017)	26
CCNE1	1	SMARCC1	5	affinity chromatography technology	Shanahan F (1999)	1
GLIS2	2	ARNT	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SKP2	2	TP73	2	affinity chromatography technology	Huttlin EL (2017)	1
ARNT	1	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	CDKN1B	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Huttlin EL (2015), Huttlin EL (2017)	3
AKT1	1	NF2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Tang X (2007), Tang X (2007), Tang X (2007), Tang X (2007), Laulajainen M (2011), Laulajainen M (2011), Laulajainen M (2011), Laulajainen M (2011), Ivanov AA (2017)	9
UHRF2	1	RB1	2	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Lai M (2016)	5
SMARCB1	1	SMARCC1	5	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Sif S (2001), Wang W (1996), Ryme J (2009), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Foster KS (2006), Foster KS (2006), Medjkane S (2004), Sif S (1998), Dallas PB (1998), Bartlett C (2011), Havugimana PC (2012), Wan C (2015)	15
SKP2	2	MRE11	3	affinity chromatography technology	Wu J (2012)	1
CCNE1	1	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Datta NS (1998), Ivanov AA (2017)	2
FOXM1	3	HERC5	2	affinity chromatography technology	Li X (2015)	1
MYC	2	BTRC	1	affinity chromatography technology, enzymatic study	Popov N (2010), Popov N (2010)	2
PRKN	1	PSMA6	1	affinity chromatography technology	Sarraf SA (2013)	1
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CCND2	2	HIST1H1A	0	enzymatic study, enzymatic study	Sweeney KJ (1997), Jiang W (1998)	2
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
CDKN2A	1	CDK6	0	unspecified method, x-ray crystallography, pull down, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Fahraeus R (1996), Russo AA (1998), Kaldis P (2001), Yarbrough WG (1999), Della Torre G (2001), Ezhevsky SA (1997), Ezhevsky SA (1997), Jones R (2007), Jones R (2007), Ramachandran N (2004), Varjosalo M (2013), Souza-Rodrigues E (2007), Huttlin EL (2015), Huttlin EL (2017), Ivanov AA (2017)	15
RB1	2	MYC	2	two hybrid, fluorescent resonance energy transfe	Adnane J (1995), Ivanov AA (2017)	2
AKAP9	13	CCNE1	1	affinity chromatography technology	Nishimura T (2005)	1
CDKN1B	1	MYC	2	affinity chromatography technology, protein complementation assay	Bahram F (2016), Bahram F (2016)	2
SMARCB1	1	MYC	2	two hybrid, two hybrid, pull down, affinity chromatography technology, pull down	Cheng SW (1999), Cheng SW (1999), Cheng SW (1999), Cheng SW (1999), Pal S (2003)	5
CDKN2A	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTNNB1	30	KAT2A	1	pull down, affinity chromatography technology	Sierra J (2006), Chen J (2010)	2
CALM1	0	SF3B1	12	pull down	Shen X (2005)	1
CDK6	0	CDKN2B	0	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, two hybrid, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Mo XL (2015), Huttlin EL (2017), Ivanov AA (2017)	8
NF2	1	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK7	0	CCT2	1	affinity chromatography technology	Jeronimo C (2007)	1
PRKN	1	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kao SY (2009), Kao SY (2009), Zhu X (2017), Zhu X (2017), Zhu X (2017)	5
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
PSMA6	1	CDK1	0	affinity chromatography technology	Sharma SS (2011)	1
CUL3	17	MCM3	2	affinity chromatography technology	Bennett EJ (2010)	1
BTRC	1	CDC25A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Ray D (2005), Jin J (2003), Jin J (2003), Honaker Y (2010), Honaker Y (2010), Gao D (2009), Donzelli M (2004), Donzelli M (2004), Jin J (2005), Busino L (2003), Busino L (2003), Busino L (2003), Busino L (2003), Kim TY (2014), Jin J (2003), Coyaud E (2015), Loveless TB (2015), Coyaud E (2015), He N (2005), He N (2005), St-Denis N (2016), Huttlin EL (2017)	23
E2F1	0	CDK2	0	pull down, enzymatic study, affinity chromatography technology, enzymatic study	Xu M (1994), Dynlacht BD (1997), Dynlacht BD (1997), Ohta T (2001)	4
GLIS2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	POLD1	5	enzymatic study	Wu SM (1998)	1
SMARCB1	1	SMARCA4	19	biochemical, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, genetic interference, affinity chromatography technology, affinity chromatography technology	Sif S (2001), Sullivan EK (2001), Wang W (1996), Wang W (1996), Otsuki T (2001), Zhao K (1998), Reyes JC (1997), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Pal S (2003), Bultman SJ (2005), Gong F (2008), Medjkane S (2004), Ito T (2008), Sif S (1998), Dallas PB (1998), Tando T (2010), Bakshi R (2010), Bakshi R (2010), Mahmoudi T (2006), Mahmoudi T (2006), Bartlett C (2011), Nishimoto N (2012), Havugimana PC (2012), Wan C (2015), Shen JP (2017), Pchelintsev NA (2013), Pchelintsev NA (2013)	30
TSC1	4	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
KLF10	1	CDK2	0	affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Lin CH (2015), Lin CH (2015), Lin CH (2015), Lin CH (2015)	4
CREBBP	29	AR	3	two hybrid, pull down, pull down, genetic interference, affinity chromatography technology, pull down	Kim J (2005), Fronsdal K (1998), Ishitani K (2003), Aarnisalo P (1998), Andersen RJ (2010), Fronsdal K (1998)	6
CDKN1B	1	HIST1H1A	0	enzymatic study	Ciarallo S (2002)	1
RASSF1	3	GSK3B	1	affinity chromatography technology	Zhou X (2012)	1
MYC	2	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	MARCKS	0	enzymatic study	Manenti S (1999)	1
CCNE1	1	NPAT	4	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Wang A (2004), Ma T (2000), Ma T (2000), Zhao J (1998), Zhao J (1998)	5
SMARCA4	19	SMARCA2	17	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Reyes JC (1997), Pal S (2003), Ito T (2008), Ito T (2008), Havugimana PC (2012)	5
NF2	1	CDK1	0	affinity chromatography technology	Zhou L (2015)	1
MYC	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	CUL3	17	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Singer JD (1999), Singer JD (1999), Singer JD (1999), Wimuttisuk W (2007), Jin X (2016), Jin X (2016), Jin X (2016)	7
KLF10	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Lin CH (2015), Lin CH (2015)	2
GRM1	4	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK4	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL4B	8	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Higa LA (2006)	2
SKP2	2	BTRC	1	affinity chromatography technology, pull down, affinity chromatography technology	Wei S (2012), Wei S (2012), Wei S (2012)	3
SMARCB1	1	SMARCA2	17	biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical	Sif S (2001), Wang W (1996), Wang W (1996), Pal S (2003), Nakamura T (2002), Ito T (2008), Sif S (1998), Havugimana PC (2012), Wan C (2015)	9
STK11	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CUL4B	8	TUBG1	2	affinity chromatography technology	Thirunavukarasou A (2015)	1
CDK5	0	RB1	2	enzymatic study	Moorthamer M (1999)	1
PRKN	1	CCNE1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Staropoli JF (2003), Veeriah S (2010), Veeriah S (2010), Gong Y (2014), Gong Y (2014)	5
FZR1	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNE1	1	CDC6	0	enzymatic study	Jiang W (1999)	1
LATS2	1	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	CDC25A	2	enzymatic study	Chang KH (2012)	1
NFYB	2	CCNE1	1	affinity chromatography technology	Yun J (2003)	1
RASSF1	3	CDKN2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	UBC	7	enzymatic study, imaging technique, enzymatic study, fluorescent resonance energy transfe, pull down, pull down, pull down, pull down, x-ray crystallography, imaging technique, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, pull down, x-ray crystallography, enzymatic study	Kondapalli C (2012), Kane LA (2014), Kane LA (2014), Koyano F (2014), Zheng X (2013), Shiba-Fukushima K (2014), Shiba-Fukushima K (2014), Kumar A (2015), Kumar A (2015), Okatsu K (2015), Okatsu K (2015), Okatsu K (2015), Yamano K (2015), Fiesel FC (2015), Ordureau A (2015), Kazlauskaite A (2015), Kazlauskaite A (2015), Kumar A (2017), Kliza K (2017)	19
SKP2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Calvisi DF (2009), Cen B (2010), Bashir T (2004), Bashir T (2004), Hu D (2011), Fukushima H (2013), Gao D (2009), Gao D (2009), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012), Huttlin EL (2017)	12
PRKN	1	FBXW7	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Staropoli JF (2003), Staropoli JF (2003), Staropoli JF (2003), Gong Y (2014)	4
E2F1	0	CREBBP	29	two hybrid, pull down	Giangrande PH (2003), Trouche D (1996)	2
CREBBP	29	FOXM1	3	affinity chromatography technology	Major ML (2004)	1
UBC	7	BTRC	1	affinity chromatography technology, enzymatic study	Matsumoto M (2005), Kumar KG (2007)	2
UHRF2	1	CTNNB1	30	far western blotting	Mori T (2011)	1
RASSF1	3	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	POLA1	0	enzymatic study, affinity chromatography technology, enzymatic study	Matsuo K (2000), Dehde S (2001), Dehde S (2001)	3
BRCA1	7	SF3B1	12	affinity chromatography technology	Ertych N (2016)	1
CDK1	0	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Deep G (2006), Olsen BB (2008), Porter LA (2002), Kabuta T (2013), Ling YH (1998), Thompson LJ (1996), Vincent I (2001)	7
CCNE1	1	PRC1	4	enzymatic study	Jiang W (1998)	1
BRCA1	7	TP73	2	affinity chromatography technology	Ibrahim N (2010)	1
BRCA1	7	E2F4	0	pull down	Wang H (1997)	1
MRE11	3	POLA1	0	genetic interference	van Pel DM (2013)	1
CUL3	17	RHOBTB3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Berthold J (2008), Berthold J (2008), Lu A (2013), Lu A (2013), Lu A (2013), Huttlin EL (2017)	7
MYC	2	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	CDK7	0	enzymatic study	Garrett S (2001)	1
CUL4B	8	CALM1	0	affinity chromatography technology	Bennett EJ (2010)	1
MYC	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP73	2	CDT1	2	affinity chromatography technology	Lunardi A (2010)	1
PRKN	1	H1F0	3	affinity chromatography technology	Zanon A (2013)	1
CDKN1B	1	CDK4	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Cariou S (2000), Guidoboni M (2005), Bustany S (2011), Hsu SP (2008), Radu M (2008), Mori S (1999), Kokontis JM (1998), Orend G (1998), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Mandal M (1998), Larrea MD (2009), Seo DW (2006), Kossatz U (2006), Kossatz U (2006), Mallampalli RK (2013), Varjosalo M (2013), Huttlin EL (2015), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	25
CDK7	0	CDK6	0	enzymatic study	Aprelikova O (1995)	1
E2F1	0	GSK3B	1	affinity chromatography technology	Zhou F (2008)	1
AURKA	1	PSMA6	1	affinity chromatography technology	Fogeron ML (2013)	1
CCND2	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UHRF2	1	CCNE1	1	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Li Y (2004)	6
NF2	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	POLA1	0	enzymatic study	Dehde S (2001)	1
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
GSK3B	1	BTRC	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Kitagawa M (1999), Gao C (2014), Gao C (2014), Gao C (2014)	4
BTRC	1	FZR1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Fukushima H (2013), Fukushima H (2013), Fukushima H (2013)	3
NFYB	2	TP73	2	affinity chromatography technology, affinity chromatography technology	Hackzell A (2002), Uramoto H (2004)	2
CDK7	0	CCND2	2	enzymatic study	Denicourt C (2008)	1
CISH	1	CCNE1	1	affinity chromatography technology	Piessevaux J (2008)	1
E2F4	0	RBL2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Iavarone A (1999), Litovchick L (2007), Schmit F (2007), Kong LJ (2006), Farkas T (2002), Osterloh L (2007), Yakovlev VA (2013), Martin N (2012), Martin N (2012)	9
KAT2A	1	CCND2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	POLA1	0	genetic interference	Toyoshima M (2012)	1
POLA1	0	CCNE1	1	affinity chromatography technology	Dehde S (2001)	1
MYC	2	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Ruffner H (1999), Ruffner H (1999), Ruffner H (1999), Wang H (1997), Chen Y (1996)	5
CUL3	17	CALM1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK6	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CTNNB1	30	HERC5	2	affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Park YS (2017)	2
CDK4	2	RBL2	5	enzymatic study	Anders L (2011)	1
CDK5	0	CCT2	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015)	2
AURKA	1	UBTF	8	pull down	Kamran M (2017)	1
AURKA	1	CDKN2A	1	affinity chromatography technology	Ewing RM (2007)	1
AURKA	1	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Ouchi M (2004), Ouchi M (2004), Maxwell CA (2011), Maxwell CA (2011), Ouchi M (2004), Ouchi M (2004), Ertych N (2016)	7
CCNE1	1	RHOBTB3	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu A (2013), Lu A (2013), Lu A (2013)	3
MYC	2	CDKN2C	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	RBL2	5	enzymatic study, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Lacy S (1997), Zhao J (1998), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Howard CM (2000), Huttlin EL (2017)	9
CCND2	2	CDKN1A	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Kehn K (2004), Bao GC (2006), Chen J (1996), Fogeron ML (2013), Rolland T (2014), Huttlin EL (2015), Chen TC (2014), Huttlin EL (2017), Welcker M (1998)	10
CCNE1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
FGFR4	6	CDKN2B	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MYC	2	CALM1	0	affinity chromatography technology, pull down	Agrawal P (2010), Raffeiner P (2017)	2
AKT1	1	ARNT	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, fluorescent resonance energy transfe	Li YM (2005), Li YM (2005), Li YM (2005), Ivanov AA (2017)	4
POLA1	0	RB1	2	affinity chromatography technology, biochemical	Takemura M (1997), Takemura M (1997)	2
MYC	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CKS2	0	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
CDK3	0	RB1	2	enzymatic study, enzymatic study	Connell-Crowley L (1997), Ren S (2004)	2
CCNE1	1	COIL	1	enzymatic study	Liu J (2000)	1
CCND2	2	FGFR4	6	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PCNA	0	CCNE1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FZR1	1	KAT2A	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RASSF1	3	TUBG1	2	pull down	Liu L (2003)	1
NF2	1	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN1A	1	CDK6	0	affinity chromatography technology, pull down, affinity chromatography technology	Selma Dagtas A (2010), Ramachandran N (2004), Huttlin EL (2017)	3
CDK2	0	MYBL2	2	enzymatic study, enzymatic study, enzymatic study	Mueller-Tidow C (2001), Bartsch O (1999), Johnson TK (1999)	3
KAT2A	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CREBBP	29	CCNE1	1	affinity chromatography technology	Wang A (2004)	1
CDK5	0	HIST1H1B	4	enzymatic study	Vincent I (2001)	1
UBC	7	CCT2	1	affinity chromatography technology	Bish RA (2007)	1
FZR1	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ARID4A	3	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lai A (1999), Lai A (1999), Lai A (2001), Lai A (2001), Suryadinata R (2011), Suryadinata R (2011)	6
CDK1	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radu M (2008), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
RASSF1	3	TERT	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK5	0	CCND2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Guidato S (1998), Varjosalo M (2013), Varjosalo M (2013), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	6
CCND2	2	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK6	0	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GSK3B	1	SF3B1	12	affinity chromatography technology	Ewing RM (2007)	1
CKS1B	0	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology	Wang W (2003), Sitry D (2002), Zhou W (2009), Ooi LC (2013), Huttlin EL (2017)	5
E2F1	0	MYBL2	2	two hybrid	Giangrande PH (2003)	1
BRCA1	7	UBTF	8	affinity chromatography technology	Johnston R (2016)	1
GLIS2	2	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKN	1	CCT2	1	affinity chromatography technology	Imai Y (2003)	1
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
ARID4A	3	RBL1	1	affinity chromatography technology	Lai A (1999)	1
TUBG1	2	AURKA	1	affinity chromatography technology, affinity chromatography technology	Molli PR (2010), Molli PR (2010)	2
SKP2	2	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Marti A (1999), Zhang Z (2005), Farhana L (2002), Salon C (2007), Swarnalatha M (2013)	6
FZR1	1	CKS1B	0	affinity chromatography technology	Bashir T (2004)	1
CDK2	0	NFYB	2	affinity chromatography technology, affinity chromatography technology	Yun J (2003), Yun J (2003)	2
CDK2	0	MARCKS	0	enzymatic study	Manenti S (1999)	1
GRM1	4	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
E2F4	0	CDK4	2	affinity chromatography technology	Boldt K (2016)	1
CDKN1A	1	RBL2	5	affinity chromatography technology	Fogeron ML (2013)	1
CDK2	0	TUBG1	2	biochemical	Nishimura T (2005)	1
CDK4	2	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NF2	1	LATS2	1	x-ray crystallography, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Li Y (2015), Yin F (2013), Ivanov AA (2017), Zhu C (2018)	4
CKS1B	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	AKT1	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down	Altiok S (1999), Xiang T (2008), Xiang T (2008), Xiang T (2008), Xiang T (2011)	5
GSK3B	1	PRKAR1A	4	affinity chromatography technology	Varjosalo M (2013)	1
CDK6	0	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
E2F4	0	KAT2A	1	affinity chromatography technology	Lang SE (2001)	1
CDKN1B	1	TSC1	4	affinity chromatography technology	Rosner M (2004)	1
GRM1	4	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCND2	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2C	0	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK2	0	E2F4	0	affinity chromatography technology	So J (2015)	1
CDK2	0	PRC1	4	enzymatic study	Jiang W (1998)	1
CDKN2B	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
UBC	7	CALM1	0	affinity chromatography technology	Bish RA (2007)	1
CREBBP	29	MYC	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, pull down, enzymatic study	de Nigris F (2007), de Nigris F (2007), Vervoorts J (2003), Vervoorts J (2003), Vervoorts J (2003), Vervoorts J (2003), Vervoorts J (2003)	7
STK11	2	GSK3B	1	affinity chromatography technology	Yan D (2012)	1
CDK2	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDC6	0	POLA1	0	biochemical	Wan C (2015)	1
KAT2A	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDKN2A	1	PCNA	0	affinity chromatography technology, affinity chromatography technology, pull down	Souza-Rodrigues E (2007), Souza-Rodrigues E (2007), Souza-Rodrigues E (2007)	3
RB1	2	SMARCA4	19	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Dunaief JL (1994), Reyes JC (1997), Qiu Z (2008), Dasgupta P (2004), Zhang HS (2000), Zhang HS (2000), Napolitano MA (2007), Dunaief JL (2002), Tu Z (2013)	9
TERT	7	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
LATS2	1	SKP2	2	affinity chromatography technology	Couzens AL (2013)	1
CCND2	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RB1	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Nicolas E (2001), Pardo PS (2002), Choubey D (1996), Fajas L (2000), Dyson N (1993), Dyson N (1993), Wu CL (1995), Taniura H (1998), Dai Y (2003), Fedele M (2006), Fedele M (2006), Brown VD (2002), De Blasio A (2005), Chau CM (2008), Dasgupta P (2004), Yang L (2011), Kruetzfeldt M (2005), Harbour JW (1999), Lee SJ (1998), Gao D (2009), Delston RB (2011), Gupta K (2000), Sdek P (2004), Flemington EK (1993), Chang YH (2012), Inoue Y (2007), Inoue Y (2007), Inoue Y (2007), Liu X (2006), Moberg K (1996), Knudsen ES (1996), Brown VD (1999), Brown VD (1999), Whitaker LL (1998), Whitaker LL (1998), Hagemeier C (1993), Bhat UG (1999), Xiao B (2003), Xiao B (2003), Vidal M (1996), Markham D (2006), Markham D (2006), Ianari A (2009), Ianari A (2009), Dhillon NK (2002), Knudsen ES (1997), Knudsen ES (1997), Gery S (2004), Gery S (2004), Kashuba E (2008), Kashuba E (2008), Pearson A (1997), Ginsberg D (1994), Welch PJ (1995), Wang J (2009), Aoki I (2012), Trimarchi JM (1998), Kumari A (2015), Gamell C (2017), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	63
E2F1	0	CDKN1A	1	imaging technique	Devgan V (2005)	1
GLIS2	2	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP73	2	RB1	2	affinity chromatography technology	Ozaki T (2003)	1
CCNE1	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McKenzie PP (2003), Shanahan F (1999), Koff A (1992), Koff A (1992), Mayer C (2004), Connor MK (2003), Boudrez A (2000), Varshochi R (2005), Jeong JH (2010), Bustany S (2011), Yeh ES (2006), Hui S (2011), Kim J (2007), Kiviharju-af Haellstroem TM (2007), Abbas T (2007), Nishimura T (2005), Matsumoto Y (2004), Harwell RM (2004), Harwell RM (2004), Peiretti A (2003), Peiretti A (2003), Kim YB (2000), Manenti S (1999), Datta NS (1998), Sheaff RJ (1997), Higashi H (1996), Higashi H (1996), Musgrove EA (1996), Vlach J (1996), Grim JE (2008), Liu S (2009), Ciarallo S (2002), Desai D (1995), Baydoun HH (2010), Baydoun HH (2010), Chu I (2007), Chu I (2007), Levkau B (1998), Poon RY (1996), Zhao J (1998), Zhao J (1998), Larrea MD (2009), Varjosalo M (2013), Varjosalo M (2013), Chan HM (2001), So J (2015), Ungermannova D (2005), Song MS (2011), Huttlin EL (2015), Hein MY (2015), Lin CH (2015), Lin CH (2015), Davis RJ (2017), Huttlin EL (2017)	54
RASSF1	3	TSC1	4	fluorescent resonance energy transfe	Ivanov AA (2017)	1
AR	3	SMARCC1	5	affinity chromatography technology, bioid	Wang Q (2004), Lempiaeinen JK (2017)	2
PCNA	0	CDC6	0	two hybrid	Saha P (1998)	1
BRCA1	7	SMARCA4	19	affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Hill DA (2004), Bochar DA (2000), Bochar DA (2000), Bochar DA (2000), Tu Z (2013), Ertych N (2016)	6