Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
NAV2 rs2254237 C antidepressants efficacy no Or people with major depressive disorder OR bipolar disorder. No significant difference in allele or genetoype frequencies were seen between patients who were or were not resistant, responsive or entered remission while taking antidepressants. Please refer to paper for definitions of a resistant, response and remittent patient. Also note that initial analyses showed that patients with major depressive disorder and the A allele were more likely to be remittent, but adding covariates (socio-demographic and clinical) to the association led to a non-significant p-value. Allele C is not associated with response to antidepressants in people with Depressive Disorder, Major as compared to allele T. 23537502 1183704047