PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TP53	0	TP73	2	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Stindt MH (2015), Puca R (2011), De Laurenzi V (1998), Di Como CJ (1999)	4
CCNA2	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CKS2	0	CCNA1	3	pull down	Radulovic M (2010)	1
SMTNL2	3	CDK2	0	affinity chromatography technology	Huttlin EL (2017)	1
UIMC1	4	TP53	0	affinity chromatography technology, pull down	Yan J (2009), Yan J (2009)	2
USP37	1	BRCA1	7	bioid	Yeh C (2015)	1
UHRF2	1	TP53	0	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011)	4
CDH2	4	SKP1	0	affinity chromatography technology	Chung FZ (2014)	1
TP53	0	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Romanova LY (2004), Romanova LY (2004), Riva F (2001), Glanzer JG (2013)	4
CCNA1	3	RPA1	0	enzymatic study	Pan ZQ (1993)	1
CCNA2	1	PKMYT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
UIMC1	4	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology	Sowa ME (2009), Cho HJ (2013), Cho HJ (2013), Cho HJ (2013), Cho HJ (2013), Cho HJ (2013)	6
UIMC1	4	CCNA2	1	affinity chromatography technology	Sowa ME (2009)	1
CDT1	2	FZR1	1	affinity chromatography technology, pull down	Sugimoto N (2008), Sugimoto N (2008)	2
RB1	2	KAT2B	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Nguyen DX (2004), Nguyen DX (2004), Nguyen DX (2004), Ianari A (2009)	4
CDKN1A	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology	Ono T (2000), McKenzie PP (2003), McKenzie PP (2003), Law BK (2002), Harper JW (1993), Harper JW (1993), Yam CH (1999), Selma Dagtas A (2010), Naderi S (2005), Varshochi R (2005), Jeong JH (2010), Hsu SP (2008), Scholz A (2003), Peiretti A (2003), Peiretti A (2003), Derjuga A (2001), Kim YB (2000), Park US (2000), Kim WH (2000), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Bendjennat M (2003), Zheleva DI (2002), Mandal M (1998), Bao GC (2006), Mattock H (2001), Chen Z (2002), Chen J (1996), Chen J (1996), Levkau B (1998), Levkau B (1998), Ramachandran N (2004), Lacy ER (2005), Akagi M (1996), Zhao J (1998), Zhang Y (1999), Poon RY (1998), Gorospe M (1996), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Hall JR (2014), Hein MY (2015), Hein MY (2015), Chen TC (2014), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	51
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
CDT1	2	ORC2	0	pull down	Ramachandran N (2004)	1
SMTNL2	3	CUL1	7	affinity chromatography technology	Huttlin EL (2017)	1
CCNA1	3	CTNNB1	30	affinity chromatography technology	Park CS (2004)	1
CUL1	7	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Michel JJ (1998)	2
EP300	36	CDK1	0	affinity chromatography technology, enzymatic study	Wang SA (2014), Wang SA (2014)	2
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
CDT1	2	GMNN	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2008), Ballabeni A (2004), Nishitani H (2004), Nishitani H (2004), Teer JK (2008), Roukos V (2007), Wong PG (2010), Sugimoto N (2004), Takeda DY (2005), Ramachandran N (2004), Higa LA (2003), Higa LA (2003), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	15
CCNA2	1	SKP1	0	affinity chromatography technology	Hein MY (2015)	1
CREBBP	29	NFYB	2	affinity chromatography technology	Leclerc GJ (2010)	1
TAF7	0	CDK7	0	pull down	Gegonne A (2008)	1
DTNBP1	1	CCNA2	1	two hybrid	Camargo LM (2007)	1
CDK1	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CCNA2	1	FXR1	0	affinity chromatography technology	Hein MY (2015)	1
TXNDC11	1	CCNA2	1	affinity chromatography technology	Huttlin EL (2017)	1
RPA1	0	CCNA2	1	pull down	Gibbs E (1996)	1
CDC20	1	HDAC2	1	biochemical, affinity chromatography technology	Yoon YM (2004), Yoon YM (2004)	2
CKS2	0	PKMYT1	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	RBL1	1	enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Leng X (2002), Zhao J (1998), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	8
USP37	1	CDT1	2	affinity chromatography technology	Hernandez-Perez S (2016)	1
DYRK1B	1	CREBBP	29	affinity chromatography technology	Varjosalo M (2013)	1
CDK4	2	CDK6	0	affinity chromatography technology, fluorescent resonance energy transfe	Varjosalo M (2013), Ivanov AA (2017)	2
PCNA	0	CDK5	0	affinity chromatography technology, affinity chromatography technology	Takasaki Y (2001), Wu SM (1998)	2
ANAPC11	0	E2F1	0	affinity chromatography technology	Nath S (2014)	1
BUB1B	0	TP73	2	affinity chromatography technology, pull down	Tomasini R (2009), Tomasini R (2009)	2
RBL1	1	CCNA2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dyson N (1993), Joaquin M (2002), Gibbs E (1996), Schulman BA (1998), Schulman BA (1998), Huttlin EL (2015), Huttlin EL (2017)	7
PSMA6	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bloom J (2006), Bloom J (2006), Bloom J (2006), Bennett EJ (2010)	4
CDC25A	2	CDK3	0	affinity chromatography technology	Li X (2016)	1
COPS5	0	CKS1B	0	affinity chromatography technology	Bennett EJ (2010)	1
UHRF2	1	CCNA2	1	far western blotting, affinity chromatography technology, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011)	3
CCNA2	1	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CDK2	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Youn CK (2005), Porter LA (2003), Law BK (2002), Connor MK (2003), Naderi S (2005), Varshochi R (2005), Hsu SP (2008), McAndrew CW (2007), Peiretti A (2003), Peiretti A (2003), Haddad MM (1999), Xu X (1999), Xu X (1999), Radu M (2008), Mori S (1999), Schulman BA (1998), Kokontis JM (1998), Orend G (1998), Wu G (1997), Liu J (1997), Sheaff RJ (1997), Vlach J (1996), Vlach J (1996), Vlach J (1997), Liu S (2009), Rosner M (2004), Ciarallo S (2002), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Chu I (2007), Chu I (2007), Levkau B (1998), Levkau B (1998), Lacy ER (2005), Zhao J (1998), Seo DW (2006), Kossatz U (2006), Grimmler M (2007), Grimmler M (2007), Varjosalo M (2013), Varjosalo M (2013), Montagnoli A (1999), So J (2015), Huttlin EL (2015), Hein MY (2015), Chen TC (2014), Lovisa S (2016), Qiu H (2016), Carrasco-Garcia E (2011), Huttlin EL (2017), Hu B (2017)	52
BRCA1	7	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lu Y (2012), Lu Y (2012), Parameswaran B (2015)	3
CCNA2	1	HELB	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	PDCD6	2	affinity chromatography technology	Fogeron ML (2013)	1
RBL1	1	CDKN1C	0	affinity chromatography technology	Joaquin M (2003)	1
CDC20	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Townsend K (2009)	3
CCNA2	1	CDK7	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Larochelle S (2006), Garrett S (2001), Huttlin EL (2015), Huttlin EL (2017)	4
CDKN1A	1	HIST1H1B	4	enzymatic study	Poon RY (1996)	1
BRCA1	7	NFYA	2	affinity chromatography technology	Fan W (2002)	1
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
CDKN1A	1	CCNA1	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, imaging technique	Zheleva DI (2002), Ramachandran N (2004), Rohaly G (2005), Heron-Milhavet L (2006), Chen TC (2014)	5
FZR1	1	CDC25A	2	affinity chromatography technology, pull down, enzymatic study	Gao D (2009), Donzelli M (2002), Donzelli M (2002)	3
BIRC6	15	ANAPC11	0	affinity chromatography technology	Kikuchi R (2014)	1
CTNNB1	30	KAT2B	2	pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ge X (2009), Ge X (2009), Ge X (2009), Ge X (2009), Ge X (2009)	5
CDK7	0	CDK2	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Drapkin R (1996), Cheng A (2005), Xu X (1999), Higashi H (1996), Aprelikova O (1995), Moisan A (2004), Larochelle S (2012), Larochelle S (2006), Larochelle S (2006), Garrett S (2001), Garrett S (2001), Lolli G (2004), Varjosalo M (2013), So J (2015)	14
CTNNB1	30	SP1	0	affinity chromatography technology	Ponce E (2014)	1
CDKN1A	1	CKS2	0	affinity chromatography technology	Fogeron ML (2013)	1
KRAS	1	POLA1	0	genetic interference	Luo J (2009)	1
FANCC	0	CCNA2	1	two hybrid	Huang F (2014)	1
KAT2B	2	HIST1H1A	0	enzymatic study	Sakaguchi K (1998)	1
EP300	36	NFYB	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004), Li Q (1998), Faniello MC (1999), Faniello MC (1999)	5
CCNA2	1	DNTTIP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
KRAS	1	COPS5	0	genetic interference	Luo J (2009)	1
GMNN	0	CDKN1A	1	pull down	Ramachandran N (2004)	1
CTNNB1	30	CREBBP	29	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ma H (2005), Sustmann C (2008), Taurin S (2006), Zhao Y (2016), Benoit YD (2017)	5
FZR1	1	GMNN	0	affinity chromatography technology, enzymatic study, pull down	Pfleger CM (2001), Williamson A (2011), Williamson A (2011)	3
TP53	0	TAF6	4	pull down, affinity chromatography technology, affinity chromatography technology	Wilhelm E (2010), Wilhelm E (2010), Wilhelm E (2010)	3
NFYA	2	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Imbriano C (2005), Imbriano C (2005), Imbriano C (2005), Di Agostino S (2006), Di Agostino S (2006), Huang X (2013)	6
CDK4	2	RBL1	1	enzymatic study	Anders L (2011)	1
CCNA1	3	CDK2	0	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, imaging technique	Sweeney C (1996), Yang R (1997), Yang R (1997), Mueller-Tidow C (2001), Brown NR (1999), Niida H (2005), Yam CH (2000), Wang H (2009), Narayanan R (2005), Harwell RM (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Peiretti A (2003), Pan ZQ (1993), Kim KS (2002), Lyapina SA (1998), Desai D (1995), Thomas DM (2004), Johnson LN (2002), Rohaly G (2005), Chen TC (2014)	22
BRCA1	7	HDAC2	1	pull down, affinity chromatography technology, genetic interference	Yarden RI (1999), Chang S (2011), Shen JP (2017)	3
TRIM33	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, enzymatic study	Xue J (2015), Xue J (2015), Xue J (2015)	3
CCNA2	1	BRCA1	7	affinity chromatography technology, pull down	Ruffner H (1999), Wang H (1997)	2
CDKN1A	1	CDK4	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Selma Dagtas A (2010), Guidoboni M (2005), Santiago FS (2007), Santiago FS (2007), Hsu SP (2008), Kehn K (2004), Kokontis JM (1998), Orend G (1998), Zheleva DI (2002), Mandal M (1998), Chen J (1996), Chen J (1996), Ramachandran N (2004), Gorospe M (1996), Fogeron ML (2013), Hukkelhoven E (2012), Hukkelhoven E (2012), Hukkelhoven E (2012), Huttlin EL (2017), Roessig L (2001)	20
SKP2	2	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique	Amador V (2007), Hwang CY (2007), Calvisi DF (2009), Bendjennat M (2003), Wu L (2012), Wu L (2012), Abbas T (2008), Ungermannova D (2005), Chen TC (2014)	9
GATA2	0	CDK4	2	affinity chromatography technology	Koga S (2007)	1
KAT2B	2	CDT1	2	enzymatic study	Glozak MA (2009)	1
SKP2	2	OFD1	3	affinity chromatography technology	Huttlin EL (2017)	1
GATA2	0	CDK2	0	affinity chromatography technology	Koga S (2007)	1
OFD1	3	SDCCAG3	3	affinity chromatography technology, bioid	Gupta GD (2015), Gupta GD (2015)	2
CCNA2	1	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Higashi H (1996), Knudsen ES (1996), Jiang W (1998), Connell-Crowley L (1997), Gaiddon C (2003), Nakanishi M (1999)	7
RAD23A	1	CCNA2	1	pull down	Jin L (2008)	1
CREBBP	29	TP73	2	pull down, pull down	Zeng X (2000), Lemasson I (2001)	2
TP73	2	CUL1	7	affinity chromatography technology	Peschiaroli A (2009)	1
COPS6	0	CDK2	0	affinity chromatography technology	Bennett EJ (2010)	1
TAF11	0	TAF6	4	affinity chromatography technology	Gupta K (2017)	1
USP37	1	CUL1	7	affinity chromatography technology	Burrows AC (2012)	1
E2F1	0	CDK7	0	affinity chromatography technology	Vandel L (1999)	1
CDT1	2	CDK1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Huttlin EL (2017)	4
COPS6	0	CDK4	2	affinity chromatography technology	Bennett EJ (2010)	1
CDT1	2	CCNA2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Teer JK (2008), Sugimoto N (2004), Sugimoto N (2004), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
E2F1	0	UHRF2	1	affinity chromatography technology, affinity chromatography technology	Lu H (2013), Lu H (2013)	2
EP300	36	GATA2	0	enzymatic study	Hayakawa F (2004)	1
CDC27	2	E2F1	0	affinity chromatography technology	Nath S (2014)	1
CDK3	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
SP1	0	NFYA	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Roder K (1999), Roder K (1999), Roder K (1999), Roder K (1999), Wang W (1999)	5
NFYA	2	CCNA2	1	pull down	Yun J (2003)	1
8339	0	UIMC1	4	bioid	Lambert JP (2015)	1
ANAPC4	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Izawa D (2011), Di Fiore B (2015), Voets E (2015)	3
TP73	2	HDAC2	1	affinity chromatography technology	Zhang J (2007)	1
ELMSAN1	4	CDK2	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
EP300	36	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji W (2014), Ianari A (2004), Aoki I (2012)	3
CDT1	2	CDC6	0	pull down, pull down, imaging technique	Sugimoto N (2008), Ramachandran N (2004), Sugimoto N (2015)	3
CCNA2	1	FEN1	1	enzymatic study, pull down, affinity chromatography technology	Henneke G (2003), Henneke G (2003), Henneke G (2003)	3
KRT1	3	CCNA2	1	affinity chromatography technology	Abbas T (2007)	1
CDK2	0	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Craney A (2016), Huttlin EL (2017)	4
SKP2	2	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Wang W (2003), Sitry D (2002), Fujita N (2002), Ji P (2006), Zancai P (2005), Ji P (2004), Iovine B (2011), Calvisi DF (2009), Spruck C (2001), Bashir T (2010), Bashir T (2010), Li P (2004), Boutonnet C (2010), Rosner M (2004), Rosner M (2004), Carrano AC (1999), Carrano AC (1999), Carrano AC (1999), Wu J (2012), Strohmaier H (2001), Rodier G (2008), Rodier G (2008), Ooi LC (2013), Yumimoto K (2013), Ooi LC (2013), Cen B (2010), Enchev RI (2012), Yumimoto K (2012), Shi P (2011), Lovisa S (2016), Cen B (2009), Chan CH (2013), Ma X (2017)	33
RBL1	1	CCNA1	3	pull down	Yang R (1999)	1
FZR1	1	USP37	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2011), Huang X (2011), Saxena N (2014), Huttlin EL (2017)	4
SP1	0	CDK1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Chuang JY (2012), Chuang JY (2012), Chuang JY (2012), Chuang JY (2012), Yang HC (2014), Yang HC (2014)	6
COPS5	0	CDT1	2	biochemical	He YJ (2006)	1
BRCA1	7	DYRK1A	36	affinity chromatography technology	Ertych N (2016)	1
CCNA2	1	TAF7	0	affinity chromatography technology	Hein MY (2015)	1
PSMD4	1	CCNA2	1	pull down	Jin L (2008)	1
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
CDK1	0	HIST1H1A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Zhan Q (1999), Horton LE (1997), Pan ZQ (1993), Pan ZQ (1993), Yarden RI (2002), Golsteyn RM (1995), Jiang W (1998), Badea T (2002), Bae Y (2013), Linares JF (2011), Sasaki T (2008), Chen M (2012), Tang J (2008)	13
SP1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Won J (2002), Zhang Y (2002), Sun JM (2002), Glasspool RM (2005), Duan H (2005), Sekhavat A (2007), Itoh Y (2007), Marshall GM (2010), Tsai PF (2011), Schnur N (2007)	10
CCNA2	1	CDKN1C	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
CCNA2	1	ITGB3BP	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Ohtoshi A (2000), Ohtoshi A (2000), Ohtoshi A (2000), Ohtoshi A (2000)	4
BRCA2	6	KAT2B	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lin HR (2003), Fuks F (1998), Fuks F (1998), Park I (2017)	4
CDK2	0	HIST1H1A	0	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Jeon Y (2007), Lunn CL (2010), Kiviharju-af Haellstroem TM (2007), Kim YB (2000), Xu X (1999), Mori S (1999), Lauper N (1998), Lauper N (1998), Orend G (1998), Wu G (1997), Horton LE (1997), Higashi H (1996), Musgrove EA (1996), Pan ZQ (1993), Pan ZQ (1993), Poon RY (1993), Sueoka N (1999), Baldassarre G (2000), Bendjennat M (2003), Liu S (2009), Sarmento LM (2005), Aprelikova O (1995), Giono LE (2007), Liu Y (2004), Dynlacht BD (1997), Mandal M (1998), Chang TS (2003), Colas P (1996), Jiang W (1998), Ezhevsky SA (1997), Thomas DM (2004), Song MS (2011), Naderi S (1999), Akagi M (1996), Lee B (2006), Grimmler M (2007), Zhang WN (2013), Iyer NG (2007), Morris L (2000), Chen M (2012), Guidoboni M (2005), Ghiani C (2001)	42
EP300	36	HIST1H1A	0	enzymatic study, enzymatic study	Loven MA (2004), Sakaguchi K (1998)	2
RB1	2	CCNA1	3	pull down, affinity chromatography technology, enzymatic study	Yang R (1999), Yang R (1999), Zarkowska T (1997)	3
E2F1	0	CCNA1	3	pull down, affinity chromatography technology, pull down	Yang R (1999), Yang R (1999), Ji P (2006)	3
CCNA2	1	CCNA2	1	affinity chromatography technology	Lin ML (2011)	1
RAD23A	1	PSMA6	1	affinity chromatography technology	Scanlon TC (2009)	1
CCNA2	1	NTAN1	0	biochemical	Wan C (2015)	1
DTNBP1	1	BRCA2	6	affinity chromatography technology	Huttlin EL (2015)	1
SAMHD1	3	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014), Huttlin EL (2017)	3
USP37	1	RPA1	0	bioid	Yeh C (2015)	1
USP37	1	CDC20	1	affinity chromatography technology	Huang X (2011)	1
CDK1	0	CDK3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL1	7	PDCD6	2	affinity chromatography technology	Bennett EJ (2010)	1
CDK7	0	HDAC2	1	affinity chromatography technology	Talukder AH (2003)	1
CDK3	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDC20	1	BUB1B	0	affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Fang G (2002), Fang G (2002), Wu H (2000), Wu H (2000), Wu H (2000), Kallio MJ (2002), Sudakin V (2001), Sudakin V (2001), Skoufias DA (2001), Nilsson J (2008), Ho CY (2010), Ho CY (2010), Garnett MJ (2009), Hutchins JR (2010), Di Fiore B (2010), Di Fiore B (2010), Mansfeld J (2011), Jia L (2011), Braunstein I (2007), Eytan E (2008), Eytan E (2008), Ma HT (2011), Miniowitz-Shemtov S (2012), Tang Z (2001), Tang Z (2001), Tang Z (2001), Tang Z (2001), Bolanos-Garcia VM (2011), Ge S (2009), Liu L (2007), Westhorpe FG (2011), Westhorpe FG (2011), Kwan PS (2013), Tian W (2012), Tian W (2012), Tian W (2012), Santaguida S (2011), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Han JS (2014), Izawa D (2014), Hein JB (2014), So J (2015), Scialpi F (2015), Scialpi F (2015), Diaz-Martinez LA (2015), Diaz-Martinez LA (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Voets E (2015), Chen TC (2014), Lischetti T (2014), Lischetti T (2014), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Huttlin EL (2017), Izawa D (2012), Jia L (2016), Jia L (2016), Hein JB (2016), Kaisari S (2017)	73
TXNDC11	1	RBL2	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BRCA1	7	CDK1	0	pull down	Wang H (1997)	1
KAT2B	2	BUB1B	0	affinity chromatography technology	Choi E (2009)	1
COPS6	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
EIF2AK2	1	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Li S (2011), Huttlin EL (2015)	2
CDC6	0	CDK2	0	affinity chromatography technology, enzymatic study	Saha P (1998), Jiang W (1999)	2
CDKN1B	1	CCNA1	3	pull down, affinity chromatography technology	Ji P (2006), Thomas DM (2004)	2
CDT1	2	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2008), Senga T (2006), Hu J (2006), Arias EE (2006), Nishitani H (2006), Tsanov N (2014), Chandrasekaran S (2011), Coleman KE (2015), Higa LA (2006)	11
CDKN1A	1	TBC1D4	6	affinity chromatography technology	Fogeron ML (2013)	1
EP300	36	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kitagawa M (2008), Inuzuka H (2012), Inuzuka H (2012), Oh M (2016)	4
CDK2	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shintani S (2000), Nair JS (2009), Takaki T (2004), Shen WH (2004), He W (2003), Peiretti A (2003), Harbour JW (1999), Horton LE (1997), Higashi H (1996), Delston RB (2011), Kim KS (2002), Chen W (2004), Liberal V (2012), Boyer Arnold N (2005), Dynlacht BD (1997), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Hara E (1997), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Gaiddon C (2003), Seo DW (2006), Zarkowska T (1997), Grimmler M (2007), Nakanishi M (1999), Pevarello P (2005), Iyer NG (2007), Chan HM (2001), Pan W (2001)	32
CDK7	0	HIST1H1A	0	enzymatic study	Drapkin R (1996)	1
CKS1B	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
FANCC	0	KRT1	3	two hybrid	Reuter TY (2003)	1
FANCC	0	CDK1	0	two hybrid, affinity chromatography technology	Reuter TY (2003), Kupfer GM (1997)	2
CDK4	2	CDC6	0	enzymatic study	Anders L (2011)	1
CDKN1A	1	CDK5	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Varjosalo M (2013), Varjosalo M (2013), Fogeron ML (2013)	4
BRCA2	6	BUB1B	0	two hybrid, pull down, affinity chromatography technology	Futamura M (2000), Futamura M (2000), Park I (2017)	3
CDT1	2	CUL1	7	affinity chromatography technology	Li X (2003)	1
CDC27	2	CTNNB1	30	pull down	Gomes NP (2006)	1
GATA2	0	SKP1	0	affinity chromatography technology	Nakajima T (2015)	1
POLA1	0	PCNA	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
PSMA6	1	CDK4	2	affinity chromatography technology	Sharma SS (2011)	1
CDC20	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Turnell AS (2005), Turnell AS (2005), Huttlin EL (2017)	3
RBL2	5	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Li Y (1993), Farkas T (2002), Huttlin EL (2015), Huttlin EL (2017)	4
RBL2	5	SKP2	2	affinity chromatography technology, enzymatic study	Bhattacharya S (2003), Tedesco D (2002)	2
EP300	36	KAT2B	2	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Kim JH (2011), Lee M (2010), Santos-Rosa H (2003), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996), Mizuguchi Y (2012)	8
CCNA2	1	PRC1	4	enzymatic study	Jiang W (1998)	1
CDK3	0	CKS2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RB1	2	CDC27	2	affinity chromatography technology, biochemical, two hybrid, pull down	Binne UK (2007), Binne UK (2007), Chen PL (1995), Chen PL (1995)	4
COPS6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Reitsma JM (2017)	7
CKS2	0	CDKN1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK4	2	SKP1	0	two hybrid	Wang J (2011)	1
CDK4	2	HIST1H1A	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study	Kim YB (2000), Sueoka N (1999), Mandal M (1998), Iyer NG (2007)	4
E2F1	0	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology	Xu M (1994), Xu M (1994), Schulman BA (1998)	3
TRIM33	4	CDC20	1	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Sedgwick GG (2012)	2
SKP1	0	PSMA6	1	affinity chromatography technology	Hauri S (2016)	1
CDC20	1	PCNA	0	affinity chromatography technology	Craney A (2016)	1
CDKN1B	1	CDK6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Radu M (2008), Bockstaele L (2006), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	6
CREBBP	29	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nath S (2011), Nath S (2011), Townsend K (2009)	3
CDC20	1	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Mansfeld J (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Wolthuis R (2008), Sedgwick GG (2012), Zhang Z (2012), Chang L (2014), Fogeron ML (2013), Hein JB (2014), Hein JB (2014), Voets E (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Craney A (2016), Sedgwick GG (2016), Qiao R (2016), Izawa D (2012), Izawa D (2012), Izawa D (2012), Izawa D (2012), Salsi V (2016)	25
CDK4	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Serrano M (1993), Xiong Y (1993), Takasaki Y (2001)	3
BRCA1	7	SSB	0	affinity chromatography technology	Ertych N (2016)	1
CDK3	0	GMNN	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK2	0	FEN1	1	enzymatic study, pull down	Henneke G (2003), Henneke G (2003)	2
CDT1	2	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Li X (2003), Li X (2003), Sugimoto N (2008), Liu E (2004), Liu E (2004), Sugimoto N (2004), Takeda DY (2005), Hein MY (2015)	9
CDK1	0	CDC20	1	enzymatic study, affinity chromatography technology, enzymatic study	Yudkovsky Y (2000), Huttlin EL (2017), Jia L (2016)	3
CDK3	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDKN1B	1	CDK5	0	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lacy ER (2005), Kabuta T (2013), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	7
COPS5	0	CDC20	1	affinity chromatography technology	Bennett EJ (2010)	1
UHRF2	1	CDK6	0	far western blotting	Mori T (2011)	1
CDK6	0	SLBP	0	enzymatic study	Anders L (2011)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
SMTNL2	3	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
CREBBP	29	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Ito K (2000), Adenuga D (2010)	2
KAT2B	2	NFYB	2	affinity chromatography technology, affinity chromatography technology	Uramoto H (2004), Uramoto H (2004)	2
CDK2	0	CREBBP	29	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CDK7	0	BRCA1	7	affinity chromatography technology	Moisan A (2004)	1
RPA1	0	DNTTIP1	0	affinity chromatography technology	Marechal A (2014)	1
PSMA6	1	PSMD4	1	biochemical, biochemical, biochemical	Hendil KB (2009), Havugimana PC (2012), Wan C (2015)	3
SP1	0	BRCA2	6	affinity chromatography technology	Tapias A (2008)	1
CDC6	0	CDKN1A	1	pull down, imaging technique	Ramachandran N (2004), Chen TC (2014)	2
USP37	1	SKP1	0	affinity chromatography technology, bioid	Burrows AC (2012), Yeh C (2015)	2
SKP2	2	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Bashir T (2010), Rosner M (2009), Rosner M (2004), Zhang H (1995), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
BRCA2	6	PCNA	0	affinity chromatography technology	Brough R (2012)	1
COPS5	0	CDKN1B	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Caballero OL (2002), Kouvaraki MA (2006), Kouvaraki MA (2006), Kouvaraki MA (2006), Hsieh YH (2007), Hwang CY (2004), Hwang CY (2004), Pan Y (2012), Wang Y (2008), Wang Y (2008), Yamaguchi F (2008), Wang Y (2014), Zhang H (2017), Zhang H (2017)	14
CDH2	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Straub BK (2003), Wahl JK (2003), Fischer L (2002), Sadot E (2002), Chung FZ (2014), Boscher C (2008)	6
DYRK1A	36	CCNA2	1	affinity chromatography technology	Varjosalo M (2013)	1
CREBBP	29	CDKN1A	1	affinity chromatography technology, imaging technique	Fritah A (2005), Chen TC (2014)	2
FXR1	0	CUL1	7	affinity chromatography technology	Qie S (2017)	1
RAD23A	1	UIMC1	4	affinity chromatography technology	Scanlon TC (2009)	1
CCNA2	1	CDC20	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Di Fiore B (2010), Di Fiore B (2010), Di Fiore B (2010), Wolthuis R (2008), Wolthuis R (2008), Ge S (2009), Townsend K (2009), Di Fiore B (2010), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Huttlin EL (2017), Izawa D (2012), Hein JB (2016)	25
UHRF2	1	SKP1	0	far western blotting	Mori T (2011)	1
TXNDC11	1	CREBBP	29	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBL1	1	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dyson N (1993), Dyson N (1993), Moberg K (1996), Dhillon NK (2002), Su S (2013), Trimarchi JM (1998)	6
KRAS	1	UHRF2	1	genetic interference	Luo J (2009)	1
BUB1B	0	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chan GK (1999), Hutchins JR (2010), Lara-Gonzalez P (2011), Mansfeld J (2011), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Eytan E (2013), Wang K (2014), Han JS (2014), Han JS (2014), Lara-Gonzalez P (2011), So J (2015), Boekhout M (2015), Kelly A (2014), Craney A (2016), Qiao R (2016)	17
CDC6	0	FZR1	1	pull down, enzymatic study, enzymatic study	Ke PY (2004), Petersen BO (2000), Cotto-Rios XM (2011)	3
CDK1	0	PKMYT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	4
SLBP	0	CDK1	0	affinity chromatography technology	Dankert JF (2016)	1
CCNA2	1	BRCA2	6	enzymatic study	Esashi F (2005)	1
RBL1	1	SP1	0	affinity chromatography technology, affinity chromatography technology	Datta PK (1995), Datta PK (1995)	2
CDC25A	2	RAD23A	1	affinity chromatography technology	Li X (2016)	1
DNTTIP1	0	ELMSAN1	4	affinity chromatography technology, biochemical, affinity chromatography technology	Bantscheff M (2011), Wan C (2015), Hein MY (2015)	3
TRIM33	4	SSB	0	affinity chromatography technology	Hein MY (2015)	1
DYRK1B	1	EP300	36	affinity chromatography technology	Varjosalo M (2013)	1
HDAC2	1	RBL1	1	affinity chromatography technology	Lai A (1999)	1
CDK6	0	RBL2	5	enzymatic study	Anders L (2011)	1
PLA2G4A	1	CDK2	0	affinity chromatography technology	Movahedi Naini S (2015)	1
CUL1	7	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lyapina SA (1998), Huttlin EL (2015), Huttlin EL (2017)	4
USP37	1	CDC27	2	affinity chromatography technology, bioid	Huang X (2011), Yeh C (2015)	2
COPS5	0	FXR1	0	affinity chromatography technology	Bennett EJ (2010)	1
CCNA2	1	CDK4	2	affinity chromatography technology, affinity chromatography technology	Datta NS (1998), Kikuchi R (2014)	2
CDK2	0	TP53	0	enzymatic study, enzymatic study, imaging technique	Luciani MG (2000), Tsai CH (2009), Chen TC (2014)	3
BRCA2	6	TP53	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Dong Y (2003), Marmorstein LY (1998)	4
GATA2	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Koga S (2007), Koga S (2007)	2
PSMD4	1	CUL1	7	pull down	Bloom J (2006)	1
CDK2	0	NFYA	2	enzymatic study, pull down, affinity chromatography technology	Yun J (2003), Yun J (2003), Yun J (2003)	3
SKP2	2	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Yam CH (1999), Calvisi DF (2009), Gao D (2009), Bashir T (2010), Yao ZP (2006), Rosner M (2009), Lyapina SA (1998), Zhang H (1995), Zhang H (1995), Inuzuka H (2012), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	17
CDK2	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Koundrioukoff S (2000), Zhang H (1993), Neganova I (2011), Wu SM (1998), Chen Z (2002), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	8
ORC1	3	ORC2	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Fujita M (2002), Vashee S (2001), Vashee S (2001), Mendez J (2002), Mendez J (2002), Ramachandran N (2004), Vermeulen M (2010), Hein MY (2015), Hein MY (2015)	11
CDKN1A	1	HDAC2	1	pull down	Garcia-Wilson E (2005)	1
GATA2	0	CUL1	7	affinity chromatography technology	Nakajima T (2015)	1
CDK2	0	BRCA2	6	enzymatic study	Esashi F (2005)	1
CDC20	1	CUL1	7	affinity chromatography technology	Wu F (2017)	1
SKP2	2	SKP1	0	affinity chromatography technology, pull down, pull down, two hybrid, x-ray crystallography, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Strack P (2000), Ng RW (1998), Ng RW (1998), Schulman BA (2000), Cenciarelli C (1999), Marti A (1999), Sabile A (2006), Ji P (2004), Wang W (2004), Tokarz S (2004), Watanabe N (2004), Lin HK (2009), Lin HK (2009), Lin HK (2009), Price CT (2009), Huang Z (2004), Wu J (2012), Bashir T (2010), Saiga T (2009), Li T (2005), Carrano AC (1999), Wu J (2012), Wu L (2012), Rodier G (2008), Swarnalatha M (2013), Yumimoto K (2013), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Tian X (2015), Liu YQ (2015), Kuchay S (2017), Chan CH (2013), Chan CH (2013), Hauri S (2016), Ma X (2017)	37
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
CDC20	1	GMNN	0	affinity chromatography technology, affinity chromatography technology	Pfleger CM (2001), Tsunematsu T (2013)	2
COPS6	0	CCNA2	1	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CDC20	1	CCNA1	3	affinity chromatography technology, two hybrid, affinity chromatography technology	Ohtoshi A (2000), Ohtoshi A (2000), Gao D (2009)	3
BRCA1	7	RPA1	0	affinity chromatography technology, imaging technique, affinity chromatography technology	Suhasini AN (2011), Mok MT (2010), Tian F (2013)	3
UHRF2	1	CDK2	0	far western blotting, affinity chromatography technology, enzymatic study	Mori T (2011), Li Y (2004), Li Y (2004)	3
CDK2	0	CDK1	0	affinity chromatography technology, affinity chromatography technology	Neganova I (2011), Huttlin EL (2017)	2
ANAPC4	0	MAD2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mansfeld J (2011), Ma HT (2011), Sedgwick GG (2012), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Sedgwick GG (2016), Izawa D (2012), Salsi V (2016)	9
FZR1	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Fogeron ML (2013), Huttlin EL (2017)	2
CCNA2	1	CDK6	0	affinity chromatography technology	Datta NS (1998)	1
CCNA1	3	SP1	0	pull down	Fojas de Borja P (2001)	1
CCNA2	1	ZC3H18	4	affinity chromatography technology	Hein MY (2015)	1
CALM1	0	TBC1D4	6	affinity chromatography technology	Boldt K (2016)	1
BUB1B	0	MAD2L1	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sudakin V (2001), Sudakin V (2001), Ho CY (2010), Bolanos-Garcia VM (2011), Tipton AR (2011), Tipton AR (2011), Tipton AR (2011), Westhorpe FG (2011), Eytan E (2013), Han JS (2013), Wang K (2014), Wang K (2014), So J (2015), Di Fiore B (2015), Di Fiore B (2015), Di Fiore B (2015), Lischetti T (2014), Tipton AR (2013), Tipton AR (2013), Boekhout M (2015), Sedgwick GG (2016), Sedgwick GG (2016), Sedgwick GG (2016)	23
CCNA2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK2	0	ORC2	0	enzymatic study, pull down	Mendez J (2002), Ramachandran N (2004)	2
CCNA2	1	TICRR	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS5	0	CDK2	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Chun Y (2013)	2
CDK2	0	CDK6	0	biochemical, imaging technique	Cheng A (2000), Chen TC (2014)	2
BRCA1	7	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2003), Maor S (2007), Maor S (2007), Abramovitch S (2003)	4
CCNA2	1	SCAPER	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CDK1	0	PRC1	4	enzymatic study	Jiang W (1998)	1
CCNA2	1	SDCCAG3	3	affinity chromatography technology	Hein MY (2015)	1
TAF6	4	TAF7	0	biochemical, affinity chromatography technology	Havugimana PC (2012), Gupta K (2017)	2
CCNA2	1	CRIPT	0	affinity chromatography technology	Hein MY (2015)	1
BIRC6	15	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Kikuchi R (2014), Kikuchi R (2014)	2
ARID4A	3	CDK2	0	enzymatic study	Suryadinata R (2011)	1
CDK1	0	FEN1	1	pull down	Henneke G (2003)	1
CDK5	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), So J (2015), Huttlin EL (2017)	3
TAF11	0	TAF7	0	affinity chromatography technology, affinity chromatography technology	Gupta K (2017), Gupta K (2017)	2
BRCA1	7	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Li H (2010), Li H (2010), Li H (2010), Ertych N (2016)	4
NFYB	2	TAF6	4	pull down	Frontini M (2002)	1
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
CDT1	2	CDK4	2	affinity chromatography technology	Liu E (2004)	1
NFYB	2	TAF11	0	pull down, pull down	Frontini M (2002), Frontini M (2002)	2
CCNA2	1	CDK1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Amador V (2007), Horton LE (1997), Lin ML (2011), Lin ML (2011), OConnor PM (1993), Varjosalo M (2013), Kikuchi R (2014), Mateo F (2009), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	13
SKP1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Min KW (2003), Lisztwan J (1998), Zheng N (2002), Ohta T (1999), Bloom J (2006), Kumar R (2005), Megumi Y (2005), Wang W (2004), Read MA (2000), Wu K (2000), Tan P (1999), Mao X (2011), Lin HK (2009), Yano H (2008), Banerjee S (2010), Gao D (2010), Chua YS (2011), Zhang M (2008), Winston JT (1999), Latres E (1999), Latres E (1999), Arai T (2003), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), Emberley ED (2012), Bennett EJ (2010), Gastaldello S (2012), Michel JJ (1998), Michel JJ (1998), Michel JJ (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Lyapina SA (1998), Furukawa M (2000), Furukawa M (2000), Liu J (2002), Liu J (2002), Liu J (2002), Yu ZK (1998), Yu ZK (1998), Postow L (2013), Cordero-Espinoza L (2013), Zhou W (2014), Zhou W (2014), Hao J (2015), Hao J (2015), Han XR (2016), Liu YQ (2015), Gorelik M (2016), Al-Yacoub N (2016), Reiterer V (2017), Hu Y (2017), Hauri S (2016), Reitsma JM (2017), Reitsma JM (2017), Chen F (2017)	59
USP37	1	HDAC2	1	bioid	Yeh C (2015)	1
BIRC6	15	CDC27	2	affinity chromatography technology	Kikuchi R (2014)	1
TRIM33	4	BUB1B	0	affinity chromatography technology	Sedgwick GG (2012)	1
COPS6	0	CDKN1B	1	affinity chromatography technology	Choi HH (2015)	1
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
KRAS	1	ANAPC4	0	genetic interference	Luo J (2009)	1
EP300	36	FEN1	1	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology	Hasan S (2001), Hasan S (2001), Hasan S (2001), Hasan S (2001), Sharma S (2005), Balakrishnan L (2010)	6
CDK1	0	CKS1B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Havugimana PC (2012), Hixon ML (1998), Varjosalo M (2013), Radulovic M (2010), Rolland T (2014), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	11
UHRF2	1	PCNA	0	far western blotting, x-ray crystallography, unspecified method, affinity chromatography technology	Mori T (2011), Chen W (2017), Chen W (2017), Lai M (2016)	4
TP53	0	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
RPA1	0	POLA1	0	affinity chromatography technology	Marechal A (2014)	1
CCNA2	1	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RPA1	0	ELMSAN1	4	affinity chromatography technology	Marechal A (2014)	1
CKS2	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDK3	0	CKS1B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
TP53	0	EP300	36	pull down, genetic interference, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, x-ray crystallography, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, unspecified method, affinity chromatography technology, enzymatic study, unspecified method, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, unspecified method	An W (2004), Pastorcic M (2000), Livengood JA (2002), Livengood JA (2002), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Grossman SR (1998), Tang Y (2008), Wang H (2008), Valbuena A (2008), Shi D (2009), Vega FM (2004), Finlan L (2004), Groenroos E (2004), Zhao Y (2006), Roe JS (2006), Pedeux R (2005), Sekaric P (2007), Pan X (2009), Tang Y (2006), Sen GS (2011), Li Y (2012), Li Y (2012), Gillotin S (2010), Grossman SR (2003), Issaeva N (2004), Kitagawa M (2008), Sabbatini P (2002), Burge S (2009), Zilfou JT (2001), Issaeva N (2004), Issaeva N (2004), Feng H (2009), Feng H (2009), Lill NL (1997), Dornan D (2004), Dornan D (2004), Di Agostino S (2006), Wells M (2008), Fath DM (2006), Kobet E (2000), Costanzo A (2002), Kumazawa T (2011), Borger DR (2006), Cui D (2013), Borger DR (2006), Lee SJ (2013), Tang HY (2006), Lin C (2011), Choi WI (2014), Ding G (2013), Kim MK (2013), Ali A (2013), Wu G (2014), Mizuguchi Y (2012), Sinha S (2012), Sinha S (2012), Her YR (2013), Her YR (2013), Wu SY (2009), Wu SY (2009), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Gu W (1997), Teufel DP (2007), Mantovani F (2007), Mantovani F (2007), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), Dornan D (2003), MacPartlin M (2005), Mujtaba S (2004), Wang YH (2003), Chen H (1999), Tang Z (2013), Graczyk A (2013), Graczyk A (2013), Chan HM (2001), Thomas MC (2005), Miller Jenkins LM (2015), Miller Jenkins LM (2015), Koh DI (2014), Koh DI (2014), Koh DI (2014), Li H (2015), Chen LF (2005), Shi D (2016), Wright DG (2016), Zhang X (2016), Procopio MG (2015), Tong Q (2015)	95
CDKN1B	1	HIST1H1B	4	enzymatic study	McAndrew CW (2007)	1
CDC27	2	TRIM33	4	affinity chromatography technology, affinity chromatography technology	Sedgwick GG (2012), Sedgwick GG (2012)	2
SP1	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Singh J (2002), Chang YC (2001), Opitz OG (2000)	3
CTNNB1	30	COPS5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang X (2009), Jumpertz S (2014), Jumpertz S (2014)	3
CCNA2	1	MTBP	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP73	2	MAD2L1	0	affinity chromatography technology	Katayama H (2012)	1
CDK1	0	GATA2	0	enzymatic study	Nakajima T (2015)	1
8339	0	ARID4A	3	bioid	Lambert JP (2015)	1
58164	0	CCNA2	1	affinity chromatography technology	Abbas T (2007)	1
CCNA2	1	PDCD6	2	affinity chromatography technology	Hein MY (2015)	1
KAT2B	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, two hybrid, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study	Jin Y (2002), Wang H (2008), Zhao Y (2006), Roe JS (2006), Perez RE (2010), Tang Y (2006), Zhao LY (2003), Liu L (1999), Liu L (1999), Sakaguchi K (1998), Harrod R (2003), Harrod R (2003), MacPartlin M (2005), Chen H (1999), Kang H (2009)	15
FZR1	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhou Y (2003), Kramer ER (1998), Farhana L (2002), Cen B (2010), Sorensen CS (2001), Binne UK (2007), Wang X (2008), Tran K (2008), Wang LY (2012), Wang LY (2012), Ban KH (2007), Lv XB (2010), Huang KT (2012), Song MS (2011), Fukushima H (2013), Lau AW (2013), Cotto-Rios XM (2011), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Choi BH (2014), Jeganathan KB (2006), Fang G (1998), Sedgwick GG (2012), Kelly A (2014), Listovsky T (2013), Pavlides SC (2016), Huttlin EL (2017)	28
ARID4A	3	CDK4	2	enzymatic study	Suryadinata R (2011)	1
DYRK1B	1	RBL1	1	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013)	3
COPS5	0	KRT1	3	affinity chromatography technology	Bennett EJ (2010)	1
CCNA2	1	CCNQ	0	affinity chromatography technology	Hein MY (2015)	1
CDK2	0	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	McAndrew CW (2007), Hale TK (2006), Deep G (2006), Cheng A (2005), Alexandrow MG (2005), Nishimura T (2005), Du J (2004), Matsumoto Y (2004), Kehn K (2004), Harwell RM (2004), Shen WH (2004), Contreras A (2003), Porter LA (2002), Esashi F (2005), Dehde S (2001)	15
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
FXR1	0	ORC2	0	affinity chromatography technology	Li S (2014)	1
KAT2B	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pediconi N (2009), Ji W (2014), Ianari A (2004), Ianari A (2004), Aoki I (2012)	5
CTNNB1	30	CDK2	0	pull down, affinity chromatography technology	Park CS (2004), Park CS (2004)	2
KRAS	1	ZC3H18	4	genetic interference	Luo J (2009)	1
PCNA	0	RPA1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ohta S (2002), Ogi T (2010), Takasaki Y (2001), Gong Z (2011), Miccoli L (2005), Han J (2014)	6
CUL1	7	KRT1	3	affinity chromatography technology	Bennett EJ (2010)	1
EP300	36	PCNA	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hasan S (2001), Hasan S (2001), Hasan S (2001), Hong R (2003), Hong R (2003), Cazzalini O (2008), Cazzalini O (2008), Naryzhny SN (2004), Cazzalini O (2014), Cazzalini O (2014)	10
PCNA	0	FEN1	1	pull down, pull down, pull down, pull down, two hybrid, pull down, pull down, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Hasan S (2001), Jonsson ZO (1998), Gary R (1997), Chen U (1996), Chen U (1996), Chen U (1996), Chen U (1996), Chen U (1996), Dianova II (2001), Dianova II (2001), Yu P (2001), Friedrich-Heineken E (2005), Wang SC (2006), Warbrick E (1997), Warbrick E (1997), Bruning JB (2004), Bruning JB (2004), Zhang Z (2012), Pichler G (2012), Takawa M (2012), Wu X (1996), Wu X (1996), Sakurai S (2005), Sharma S (2004), Han J (2014), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	30
SKP2	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Ji P (2004), Ji P (2004)	2
CDK1	0	CKS2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Varjosalo M (2013), Radulovic M (2010), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
OFD1	3	CCNA2	1	bioid	Gupta GD (2015)	1
CDK2	0	GMNN	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CDK3	0	CDT1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	SKP1	0	affinity chromatography technology	Fogeron ML (2013)	1
ANAPC4	0	FZR1	1	biochemical, biochemical, unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Boekhout M (2015), Huttlin EL (2017)	6
CCNA2	1	CDC27	2	affinity chromatography technology	Mateo F (2009)	1
TRIM33	4	CCNA2	1	affinity chromatography technology	Sedgwick GG (2012)	1
TP53	0	NFYB	2	affinity chromatography technology, affinity chromatography technology	Imbriano C (2005), Di Agostino S (2006)	2
BRCA2	6	BRCA1	7	affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sarkisian CJ (2001), Reuter TY (2003), Dong Y (2003), Chen J (1998), Chen J (1998), Villarroel MC (2011), Kumaraswamy E (2007), Sy SM (2009), Sy SM (2009), Sy SM (2009), Johnson N (2013), Hill SJ (2014), Loke J (2015)	13
TRAF3IP1	3	CCNA2	1	two hybrid	Camargo LM (2007)	1
FZR1	1	ANAPC11	0	affinity chromatography technology, pull down, unspecified method	Bassermann F (2008), Vodermaier HC (2003), Vodermaier HC (2003)	3
CTNNB1	30	CCNA2	1	pull down, affinity chromatography technology	Park CS (2004), Park CS (2004)	2
DYRK1A	36	CREBBP	29	affinity chromatography technology	Varjosalo M (2013)	1
CDK6	0	RBL1	1	enzymatic study	Anders L (2011)	1
BRCA1	7	RBL1	1	imaging technique, pull down	Fan S (2001), Fan S (2001)	2
BRCA1	7	PSMA6	1	two hybrid	Woods NT (2012)	1
PSMD4	1	RPA1	0	affinity chromatography technology	Galanty Y (2012)	1
CKS1B	0	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDK2	0	TAF7	0	affinity chromatography technology	Hein MY (2015)	1
CDKN1C	0	CDK4	2	pull down, affinity chromatography technology	Reynaud EG (2000), Reynaud EG (2000)	2
ANAPC4	0	CDK1	0	affinity chromatography technology	Voets E (2015)	1
CREBBP	29	CDH2	4	affinity chromatography technology	Marambaud P (2003)	1
EP300	36	COPS6	0	two hybrid	Stelzl U (2005)	1
CKS1B	0	CDC27	2	pull down	Di Fiore B (2010)	1
RBL2	5	CCNA1	3	pull down	Yang R (1999)	1
RB1	2	CDKN1C	0	pull down	Nakanishi M (1999)	1
NFYB	2	CCNA2	1	affinity chromatography technology	Yun J (2003)	1
NFYA	2	NFYB	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, biochemical, affinity chromatography technology	Mantovani R (1994), Hu Q (2006), Imbriano C (2005), Yun J (2003), Rolland T (2014), Wan C (2015), Hein MY (2015)	7
POLA1	0	TP53	0	affinity chromatography technology	Melle C (2002)	1
CCNA2	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Amador V (2007), Wu G (1997), Lin ML (2011), Chen J (1996), Levkau B (1998), Poon RY (1996), Fogeron ML (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	11
CCNA2	1	PHF8	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK2	0	SSB	0	affinity chromatography technology	Neganova I (2011)	1
PSMA6	1	CDK2	0	affinity chromatography technology, affinity chromatography technology	Sharma SS (2011), Neganova I (2011)	2
CREBBP	29	PCNA	0	affinity chromatography technology, pull down, enzymatic study	Cazzalini O (2014), Cazzalini O (2014), Cazzalini O (2014)	3
POLA1	0	CCNA2	1	affinity chromatography technology, enzymatic study	Dehde S (2001), Dehde S (2001)	2
GMNN	0	SKP2	2	affinity chromatography technology	Huttlin EL (2017)	1
SLBP	0	CDK2	0	affinity chromatography technology	Dankert JF (2016)	1
CDK6	0	HIST1H1A	0	enzymatic study, enzymatic study	Jiang W (1998), Iyer NG (2007)	2
HDAC2	1	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lai A (1999), Lai A (1999), Chan HM (2001), Khan MM (2001), Sun JM (2007)	5
CDC6	0	CDC20	1	pull down	Ke PY (2004)	1
TP53	0	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Borellini F (1993), Jin W (2008), Dhar SK (2006), Lagger G (2003), Lagger G (2003), Lagger G (2003), Lagger G (2003), Sengupta S (2005), Sengupta S (2005), Lin RK (2010), Kim HA (2011), Sawaya BE (1998), St Clair S (2004), Innocente SA (2005), Innocente SA (2005), Ohlsson C (1998), Kong X (2013), Bocangel D (2009), Bocangel D (2009)	19
FZR1	1	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Stewart S (2005), Stewart S (2005), Wang Y (2007), Wang Y (2007), Tian W (2012), Hyun SY (2013), Hyun SY (2013)	7
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
CDK4	2	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Nair JS (2009), Takaki T (2004), Deep G (2006), Kehn K (2004), Scholz A (2003), Gladden AB (2003), Mori S (1999), Higashi H (1996), Musgrove EA (1996), Sarmento LM (2005), Kim KS (2002), Li J (2002), Garcia-Morales P (2006), Tsai CH (2009), Miralem T (2003), Toji S (2004), Halder SK (2005), Dynlacht BD (1997), Mandal M (1998), Voit R (1999), Annicotte JS (2006), Connell-Crowley L (1997), Matsuura I (2004), Chen J (1996), Kitagawa M (1996), Anders L (2011), Gaiddon C (2003), Seo DW (2006), Kabuta T (2013), Lee B (2006), Kossatz U (2006), Zarkowska T (1997), Nakanishi M (1999), Iyer NG (2007), Guidoboni M (2005), Barbash O (2009), Wang C (2001), Denicourt C (2008), Pan W (2001)	39
BRCA1	7	RBL2	5	imaging technique, pull down	Fan S (2001), Fan S (2001)	2
TP73	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Katayama H (2012), Katayama H (2012)	2
CREBBP	29	SP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Goto T (2006), Leclerc GJ (2010), Chuang JY (2012), Guo W (2014)	4
CCNA2	1	USP6NL	2	affinity chromatography technology	Hein MY (2015)	1
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
CUL1	7	FZR1	1	affinity chromatography technology, affinity chromatography technology	Fukushima H (2013), Fukushima H (2013)	2
CDC20	1	CKS2	0	affinity chromatography technology	Huttlin EL (2017)	1
CDC25A	2	CCNA2	1	affinity chromatography technology	Li X (2016)	1
CCNA2	1	CDKN1B	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joaquin M (2003), Schulman BA (1998), Datta NS (1998), Vlach J (1997), Levkau B (1998), Grimmler M (2007), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CREBBP	29	NFYA	2	affinity chromatography technology, affinity chromatography technology	Huang X (2013), Huang X (2013)	2
BUB1B	0	CCNA2	1	pull down	Di Fiore B (2015)	1
EIF2AK2	1	SSB	0	affinity chromatography technology	Li S (2011)	1
COPS5	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Guo H (2016), Guo H (2016)	2
CCNA1	3	CDC25A	2	affinity chromatography technology, affinity chromatography technology	Liu D (2000), Li X (2016)	2
HERC5	2	CDKN1A	1	pull down	Mitsui K (1999)	1
CREBBP	29	TP53	0	enzymatic study, pull down, genetic interference, pull down, enzymatic study, fluorescent resonance energy transfe, enzymatic study, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, pull down, enzymatic study, pull down, affinity chromatography technology, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, enzymatic study, enzymatic study, pull down, x-ray crystallography, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Ito A (2002), Livengood JA (2002), Livengood JA (2002), Giebler HA (2000), Tang Y (2008), Jenkins LM (2009), Shi D (2009), Zhao Y (2006), Saifudeen Z (2005), Scolnick DM (1997), Scolnick DM (1997), Gu W (1997), Gu W (1997), Matsuda S (2004), Pasqualucci L (2011), Lee SK (1999), Dai C (2011), Lee CW (2010), Ferreon JC (2009), Ruas JL (2010), Ruas JL (2010), Huang WC (2007), Huang WC (2007), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Mujtaba S (2004), Col E (2002), Jansma AL (2014), Jansma AL (2014), Krois AS (2016), Hasegawa K (2008), Huang X (2013), Huang X (2013), Piskacek M (2016)	35
FZR1	1	CCNA1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sorensen CS (2001), Sorensen CS (2001), Gao D (2009), Fukushima H (2013)	4
ARID4A	3	CDK1	0	enzymatic study	Suryadinata R (2011)	1
RBL2	5	RBL1	1	affinity chromatography technology	Litovchick L (2007)	1
SKP2	2	CKS1B	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, pull down, x-ray crystallography, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Wang W (2003), Wang W (2003), Sitry D (2002), Sitry D (2002), Ganoth D (2001), Calvisi DF (2008), Xu S (2007), Ungermannova D (2005), Spruck C (2001), Yao ZP (2006), Seeliger MA (2005), Huang KS (2005), Rodier G (2008), Ungermannova D (2013), Radulovic M (2010), Huttlin EL (2017)	16
COPS5	0	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
CDT1	2	CDC20	1	pull down	Sugimoto N (2008)	1
DNTTIP1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013)	3
CDK1	0	CDC6	0	enzymatic study	Jiang W (1999)	1
CKS1B	0	SKP1	0	pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology	Yao ZP (2006), Seeliger MA (2005), Radulovic M (2010), Ungermannova D (2013), Hauri S (2016)	5
CDK4	2	SLBP	0	enzymatic study	Anders L (2011)	1
CDC25A	2	CDK2	0	pull down, enzymatic study, affinity chromatography technology	Xu X (1996), Cheng A (2005), Li X (2016)	3
SP1	0	CCNA2	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down	Wang CH (2006), Fojas de Borja P (2001), Haidweger E (2001), Haidweger E (2001)	4
UHRF2	1	CDK4	2	far western blotting	Mori T (2011)	1
BRCA1	7	CDK4	2	pull down, enzymatic study, enzymatic study	Wang H (1997), Kehn K (2007), Miralem T (2003)	3
8339	0	DNTTIP1	0	bioid	Lambert JP (2015)	1
CDK6	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Garcia-Morales P (2006), Aprelikova O (1995), Yarbrough WG (1999), Dynlacht BD (1997), Jiang W (1998), Anders L (2011), Nakanishi M (1999), Iyer NG (2007)	8
BRCA2	6	RPA1	0	pull down, affinity chromatography technology	Wong JM (2003), Wong JM (2003)	2
CUL1	7	CKS1B	0	affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Radulovic M (2010), Huttlin EL (2017)	3
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
DYRK1B	1	RB1	2	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013)	3
BRCA1	7	UIMC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Kim H (2007), Kim H (2007), Sobhian B (2007), Sobhian B (2007), Sowa ME (2009), Strauss C (2011), Strauss C (2011), Feng L (2009), Feng L (2009), Yan J (2007), Wang B (2007), Wang B (2007), Wang B (2007), Nikkilae J (2009), Nikkilae J (2009), Mok MT (2010), Johnson N (2013), Hill SJ (2014), Hu Y (2014), Hu Y (2014), Hu Y (2014), Renaud E (2016), Li Y (2017)	23
CDKN1C	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Kamura T (2003), Calvisi DF (2009), Kamura T (2003)	3
PHF8	6	FZR1	1	affinity chromatography technology	Lim HJ (2013)	1
DYRK1A	36	RBL1	1	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013)	3
OFD1	3	TP53	0	affinity chromatography technology	Gupta GD (2015)	1
CUL1	7	SSB	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	E2F1	0	enzymatic study	Dynlacht BD (1997)	1
CKS2	0	GMNN	0	affinity chromatography technology	Huttlin EL (2017)	1
CDC27	2	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Mansfeld J (2011), Lara-Gonzalez P (2011), Mansfeld J (2011), Izawa D (2011), Ma HT (2011), Ma HT (2011), Ma HT (2011), Dube P (2005), Holzmann J (2011), Wolthuis R (2008), Havugimana PC (2012), Uzunova K (2012), Song MS (2011), Zhang Z (2012), Chang L (2014), Hein JB (2014), Vodermaier HC (2003), Vodermaier HC (2003), Vodermaier HC (2003), Tran K (2010), Chang L (2015), Yamaguchi M (2015), Wan C (2015), Hein MY (2015), Voets E (2015), Masuda K (2015), Boekhout M (2015), Craney A (2016), Qiao R (2016), Izawa D (2012), Hein JB (2016)	34
CCNA1	3	HIST1H1B	4	enzymatic study, enzymatic study	Cheng A (2005), Dehde S (2001)	2
RBL2	5	E2F1	0	affinity chromatography technology	Dhillon NK (2002)	1
SKP2	2	ORC1	3	pull down, affinity chromatography technology	Mendez J (2002), Mendez J (2002)	2
CUL1	7	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
CDT1	2	CDK2	0	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Liu E (2004), Sugimoto N (2004), Sugimoto N (2004), Takeda DY (2005), Varjosalo M (2013), Hein MY (2015)	6
COPS6	0	SAMHD1	3	affinity chromatography technology	Bennett EJ (2010)	1
CKS1B	0	137529	0	pull down	Seeliger MA (2005)	1
DYRK1A	36	EP300	36	affinity chromatography technology	Varjosalo M (2013)	1
CDK1	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDKN1A	1	CDKN1B	1	genetic interference, imaging technique	Hsu SP (2008), Chen TC (2014)	2
CCNA2	1	HDAC2	1	affinity chromatography technology	Hein MY (2015)	1
CDK6	0	CDC6	0	enzymatic study	Anders L (2011)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
COPS6	0	CCNA1	3	affinity chromatography technology	Bennett EJ (2010)	1
RAD23A	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Brignone C (2004), Hsieh HC (2005)	2
PSMA6	1	COPS5	0	affinity chromatography technology	Huang X (2005)	1
CDK5	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Zhang J (2012), Cataldo F (2013), Maestre C (2008), Maestre C (2008)	4
PCNA	0	RAD23A	1	biochemical	Kristensen AR (2012)	1
CDKN1A	1	PCNA	0	two hybrid, pull down, pull down, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Frouin I (2003), Watanabe H (1998), Fotedar R (1996), Jonsson ZO (1998), Gulbis JM (1996), Touitou R (2001), Yu P (2001), Yu P (2001), Chen X (2007), Chen X (2007), Wang SC (2006), Carujo S (2006), Garcia-Wilson E (2005), Howlett NG (2009), Jin Y (2008), Lee JY (2009), Ando T (2001), Ando T (2001), Takasaki Y (2001), Logette E (2011), Mistafa O (2010), Mistafa O (2010), Bruning JB (2004), Punchihewa C (2012), Mattock H (2001), Waga S (1994), Waga S (1994), Poon RY (1996), Zhang Y (1999), Warbrick E (1995), Warbrick E (1995), Poon RY (1998), Poon RY (1998), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Rizzardi LF (2014), Trombetta A (2013), Trombetta A (2013), Kim DH (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Coleman KE (2015), Huttlin EL (2017), Roessig L (2001), Roessig L (2001)	48
TP73	2	KAT2B	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhao LY (2003), Zhao LY (2003), Zhao LY (2003), Zhao LY (2003), Hoffmann A (2008)	5
RB1	2	TP53	0	affinity chromatography technology, pull down	Delston RB (2011), Sommer MH (1994)	2
CCNA1	3	SKP2	2	affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ji P (2006), Ji P (2006), Ji P (2006), Yam CH (2000), Gao D (2009), Ji P (2007)	6
RAD23A	1	CREBBP	29	two hybrid, pull down	Zhu Q (2001), Zhu Q (2001)	2
RAD23A	1	PSMD4	1	two hybrid, pull down, x-ray crystallography, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Hiyama H (1999), Mueller TD (2003), Kang Y (2007), Kang Y (2007), Wang Q (2003), Walters KJ (2003), Walters KJ (2002), Scanlon TC (2009), Hsieh HC (2005)	9
E2F1	0	FZR1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Budhavarapu VN (2012), Budhavarapu VN (2012), Budhavarapu VN (2012), Singh RK (2017)	4
CDK2	0	SP1	0	enzymatic study	Fojas de Borja P (2001)	1
BRCA1	7	E2F1	0	affinity chromatography technology	Gorski JJ (2011)	1
CDK2	0	RPA1	0	enzymatic study	Pan ZQ (1993)	1
KRAS	1	CCNA2	1	genetic interference	Luo J (2009)	1
TP53	0	BIRC6	15	affinity chromatography technology, affinity chromatography technology	Tang W (2015), Tang W (2015)	2
CDC27	2	ANAPC11	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Vodermaier HC (2003), Gmachl M (2000), Kraft C (2003), Dube P (2005), Lu L (2013), Gmachl M (2000), Vodermaier HC (2003), Craney A (2016)	8
EIF2AK2	1	CDK3	0	affinity chromatography technology	Li S (2011)	1
CDK6	0	CTNNB1	30	imaging technique	Chen TC (2014)	1
TP53	0	TBC1D4	6	affinity chromatography technology	Fogeron ML (2013)	1
EP300	36	CDT1	2	enzymatic study	Glozak MA (2009)	1
CCNA2	1	HIST1H1A	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Sharma SS (2011), Wu G (1997), Horton LE (1997), Higashi H (1996), Liu S (2009), Ciarallo S (2002), Jiang W (1998)	7
CCNA2	1	PLEKHG2	5	affinity chromatography technology	Huttlin EL (2015)	1
KRAS	1	CDC27	2	genetic interference	Luo J (2009)	1
CDC25A	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2003), Donzelli M (2004), Busino L (2003), Donzelli M (2002), He N (2005), Li X (2016)	6
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
CDKN1A	1	KAT2B	2	affinity chromatography technology, affinity chromatography technology	Dai M (2012), Dai M (2012)	2
CCNA2	1	CKS2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Huttlin EL (2017)	4
TP53	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Banks D (2006), Banks D (2006), Hampp S (2016), Hampp S (2016)	4
KRAS	1	DNTTIP1	0	genetic interference	Luo J (2009)	1
SLBP	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Dankert JF (2016), Dankert JF (2016)	2
SKP1	0	CDKN1A	1	imaging technique	Chen TC (2014)	1
SRRT	5	ZC3H18	4	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
BRCA1	7	SKP1	0	affinity chromatography technology, affinity chromatography technology	Lu Y (2012), Lu Y (2012)	2
COPS5	0	SKP2	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
SLBP	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dankert JF (2017), Dankert JF (2016), Dankert JF (2016)	3
BRCA1	7	PSMD4	1	affinity chromatography technology	Ertych N (2016)	1
CCNA2	1	SRRT	5	affinity chromatography technology	Hein MY (2015)	1
CCNA2	1	TAF11	0	affinity chromatography technology	Hein MY (2015)	1
CREBBP	29	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Crusselle-Davis VJ (2007), Dohda T (2004), Dohda T (2004)	3
HELB	1	POLA1	0	pull down	Taneja P (2002)	1
CCNA1	3	CDK1	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology	Sweeney C (1996), Lukas J (1992), Desai D (1995), Rohaly G (2005)	4
TP53	0	CDKN1C	0	affinity chromatography technology	Kikuchi J (2003)	1
CDC20	1	CDKN1A	1	affinity chromatography technology, affinity chromatography technology	Amador V (2007), Fogeron ML (2013)	2
HERC5	2	CCNA2	1	pull down	Mitsui K (1999)	1
NFYA	2	EP300	36	affinity chromatography technology, affinity chromatography technology	Ahn J (2011), Di Agostino S (2006)	2
CDK7	0	TP53	0	enzymatic study, affinity chromatography technology, enzymatic study, pull down	Ko LJ (1997), Schneider E (1998), Lu H (1997), Lu H (1997)	4
CDK7	0	CDKN1B	1	affinity chromatography technology	Huttlin EL (2017)	1
CREBBP	29	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Pao GM (2000), Pao GM (2000), Benezra M (2003), Fan S (2002), Fan S (2002), Neish AS (1998), Nakuci E (2006), Crowe DL (2006), Chai YL (1999)	9
CDK2	0	TP73	2	enzymatic study	Gaiddon C (2003)	1
DYRK1B	1	RBL2	5	affinity chromatography technology	Varjosalo M (2013)	1
CDKN1A	1	COPS6	0	two hybrid	Vinayagam A (2011)	1
GIP	0	CCNA2	1	affinity chromatography technology	Huttlin EL (2017)	1
UHRF2	1	CDK1	0	far western blotting	Mori T (2011)	1
CDC27	2	CDKN1A	1	affinity chromatography technology	Amador V (2007)	1
CUL1	7	CALM1	0	affinity chromatography technology	Bennett EJ (2010)	1
SKP2	2	TP73	2	affinity chromatography technology	Huttlin EL (2017)	1
UHRF2	1	RB1	2	far western blotting, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Mori T (2011), Mori T (2011), Mori T (2011), Mori T (2011), Lai M (2016)	5
CDC20	1	MAD2L1	0	affinity chromatography technology, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, unspecified method, pull down, affinity chromatography technology	Zhang Y (2001), Sihn CR (2003), Luo X (2000), Sironi L (2001), DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kallio M (1998), Fang G (1998), Fang G (1998), Skoufias DA (2001), Nilsson J (2008), Privette LM (2008), Stegmeier F (2007), Ho CY (2010), Ho CY (2010), Mansfeld J (2011), Gao YF (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Townsend K (2009), Lee YJ (2008), DAngiolella V (2003), Tang Z (2001), Tang Z (2001), Sironi L (2001), Sironi L (2001), Ge S (2009), Mapelli M (2007), Tipton AR (2011), Mondal G (2006), Mondal G (2006), Westhorpe FG (2011), De Antoni A (2005), De Antoni A (2005), Kwan PS (2013), Katayama H (2012), Fava LL (2011), Santaguida S (2011), Mapelli M (2006), Eytan E (2013), Eytan E (2013), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Eytan E (2014), Hein JB (2014), Yen AH (2010), Yen AH (2010), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Sedgwick GG (2016), Sedgwick GG (2016), Izawa D (2012), Izawa D (2012), Jia L (2016), Jia L (2016), Kaisari S (2017), Yang M (2008), Kim S (2010), Kim S (2010)	70
TP73	2	EP300	36	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Strano S (2005), Uramoto H (2004), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Zeng X (2000), Mantovani F (2004), Burge S (2009), Burge S (2009), Costanzo A (2002), Hoffmann A (2008), Kramer D (2015)	13
CDK3	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Fogeron ML (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CDK2	0	CKS1B	0	x-ray crystallography, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Bourne Y (1996), Xu S (2007), Yao ZP (2006), Seeliger MA (2005), Varjosalo M (2013), Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	12
FANCC	0	EIF2AK2	1	affinity chromatography technology, affinity chromatography technology	Pang Q (2002), Zhang X (2004)	2
HDAC2	1	BUB1B	0	affinity chromatography technology, affinity chromatography technology	Park I (2017), Park I (2017)	2
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
CCNA2	1	MAD2L1	0	unspecified method	Di Fiore B (2015)	1
SAMHD1	3	CDK1	0	affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014)	2
8339	0	SLBP	0	bioid	Lambert JP (2015)	1
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
CTNNB1	30	EP300	36	genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, genetic interference, affinity chromatography technology	Kennell JA (2003), Sun Y (2000), Sun Y (2000), Sun Y (2000), Saegusa M (2005), Daniels DL (2002), Levy L (2004), Labalette C (2004), Lee YH (2006), Zhao Y (2016)	10
CDKN1C	0	PCNA	0	two hybrid, affinity chromatography technology, pull down	Watanabe H (1998), Watanabe H (1998), Watanabe H (1998)	3
TP53	0	EIF2AK2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Cuddihy AR (1999), Cuddihy AR (1999), Cuddihy AR (1999), Cuddihy AR (1999), Cuddihy AR (1999), Morel M (2009), Morel M (2009)	7
CDK3	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
ORC2	0	CCNA2	1	affinity chromatography technology	Mendez J (2002)	1
COPS5	0	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
USP37	1	CCNA2	1	affinity chromatography technology, enzymatic study	Huang X (2011), Huang X (2011)	2
CUL1	7	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015)	2
CDC20	1	ANAPC11	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study	Nilsson J (2008), Chen TC (2014), Lee SB (2015), Alfieri C (2016)	4
CCNA1	3	HIST1H1A	0	enzymatic study, enzymatic study, enzymatic study	Sweeney C (1996), Pan ZQ (1993), Bastians H (1998)	3
PSMA6	1	CDK1	0	affinity chromatography technology	Sharma SS (2011)	1
FZR1	1	TP53	0	enzymatic study	Gmachl M (2000)	1
E2F1	0	CDK2	0	pull down, enzymatic study, affinity chromatography technology, enzymatic study	Xu M (1994), Dynlacht BD (1997), Dynlacht BD (1997), Ohta T (2001)	4
TXNDC11	1	RBL1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP37	1	ANAPC4	0	bioid	Yeh C (2015)	1
CDC25A	2	NFYA	2	two hybrid	Wang J (2011)	1
CKS1B	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jackman M (2002), Wolthuis R (2008), Mateo F (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
CCNA2	1	137529	0	affinity chromatography technology	Mateo F (2009)	1
CDKN1B	1	HIST1H1A	0	enzymatic study	Ciarallo S (2002)	1
CCNA2	1	SSB	0	affinity chromatography technology	Hein MY (2015)	1
CDK1	0	TP53	0	enzymatic study, affinity chromatography technology	Luciani MG (2000), Ababneh M (2001)	2
CALM1	0	SCAPER	5	pull down	Shen X (2005)	1
PHF8	6	CDC27	2	affinity chromatography technology	Lim HJ (2013)	1
CTNNB1	30	CUL1	7	affinity chromatography technology	Read MA (2000)	1
CDT1	2	ORC1	3	pull down	Ramachandran N (2004)	1
CDT1	2	CCNA1	3	affinity chromatography technology, affinity chromatography technology	Nishitani H (2004), Liu E (2004)	2
CUL1	7	CDK4	2	affinity chromatography technology	Bennett EJ (2010)	1
CDK2	0	USP37	1	enzymatic study, bioid	Huang X (2011), Yeh C (2015)	2
CDK2	0	SKP1	0	x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao ZP (2006), Lyapina SA (1998), Zhang H (1995), Varjosalo M (2013), So J (2015), Hein MY (2015)	6
CDKN1B	1	SKP1	0	unspecified method, unspecified method	Carrano AC (1999), Ooi LC (2013)	2
CDK5	0	RB1	2	enzymatic study	Moorthamer M (1999)	1
ANAPC4	0	ANAPC11	0	affinity chromatography technology, biochemical, biochemical, pull down, biochemical, affinity chromatography technology	Mansfeld J (2011), Zhang Z (2012), Chang L (2014), Vodermaier HC (2003), Chang L (2015), Yamaguchi M (2015)	6
BUB1B	0	PSMA6	1	affinity chromatography technology	So J (2015)	1
FZR1	1	CDK6	0	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CCNA2	1	TAF6	4	affinity chromatography technology	Hein MY (2015)	1
CDK5	0	CDC25A	2	enzymatic study	Chang KH (2012)	1
SKP2	2	FZR1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Calvisi DF (2009), Cen B (2010), Bashir T (2004), Bashir T (2004), Hu D (2011), Fukushima H (2013), Gao D (2009), Gao D (2009), Inuzuka H (2012), Inuzuka H (2012), Inuzuka H (2012), Huttlin EL (2017)	12
SLBP	0	CUL1	7	affinity chromatography technology	Dankert JF (2016)	1
E2F1	0	CREBBP	29	two hybrid, pull down	Giangrande PH (2003), Trouche D (1996)	2
DTNBP1	1	SDCCAG3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NFYB	2	SP1	0	affinity chromatography technology	Leclerc GJ (2010)	1
SAMHD1	3	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014), Huttlin EL (2015), Huttlin EL (2017)	4
CCNA2	1	FZR1	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Mateo F (2009), Jin L (2008), Mateo F (2009), Mateo F (2009), Huttlin EL (2015), Williamson A (2011), Huttlin EL (2017), Choudhury R (2016)	8
UHRF2	1	CTNNB1	30	far western blotting	Mori T (2011)	1
CDK2	0	POLA1	0	enzymatic study, affinity chromatography technology, enzymatic study	Matsuo K (2000), Dehde S (2001), Dehde S (2001)	3
CDC20	1	CKS1B	0	affinity chromatography technology, affinity chromatography technology	Bashir T (2004), Huttlin EL (2017)	2
TP53	0	HDAC2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li P (2010), Insinga A (2004), Sun JM (2007), Tian B (2011), Adenuga D (2010), Brandl A (2012)	6
CDK1	0	HIST1H1B	4	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Deep G (2006), Olsen BB (2008), Porter LA (2002), Kabuta T (2013), Ling YH (1998), Thompson LJ (1996), Vincent I (2001)	7
CKS1B	0	PKMYT1	1	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	TP73	2	affinity chromatography technology	Ibrahim N (2010)	1
OFD1	3	CDK2	0	bioid	Gupta GD (2015)	1
CDC25A	2	CDC20	1	affinity chromatography technology	Li X (2016)	1
CCNA2	1	TBC1D4	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ANAPC11	0	CCNA2	1	affinity chromatography technology	Kikuchi R (2014)	1
8339	0	PRC1	4	bioid	Lambert JP (2015)	1
COPS6	0	KRT1	3	affinity chromatography technology	Bennett EJ (2010)	1
CDK1	0	CDK7	0	enzymatic study	Garrett S (2001)	1
COPS5	0	SSB	0	affinity chromatography technology	Bennett EJ (2010)	1
BUB1B	0	ANAPC4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hutchins JR (2010), Mansfeld J (2011), Izawa D (2011), Sedgwick GG (2012), Hein JB (2014), Di Fiore B (2015), Voets E (2015), Tipton AR (2013), Boekhout M (2015), Boekhout M (2015), Sedgwick GG (2016), Izawa D (2012), Salsi V (2016)	13
TP73	2	CDT1	2	affinity chromatography technology	Lunardi A (2010)	1
CDKN1B	1	CDK4	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Lin J (2001), Cariou S (2000), Guidoboni M (2005), Bustany S (2011), Hsu SP (2008), Radu M (2008), Mori S (1999), Kokontis JM (1998), Orend G (1998), Vlach J (1996), Vlach J (1997), Ciarallo S (2002), Wang Y (2008), Bockstaele L (2006), Mandal M (1998), Larrea MD (2009), Seo DW (2006), Kossatz U (2006), Kossatz U (2006), Mallampalli RK (2013), Varjosalo M (2013), Huttlin EL (2015), Chen TC (2014), Carrasco-Garcia E (2011), Huttlin EL (2017)	25
COPS6	0	CDK3	0	affinity chromatography technology	Bennett EJ (2010)	1
CDK7	0	CDK6	0	enzymatic study	Aprelikova O (1995)	1
CKS1B	0	CCNA1	3	pull down	Radulovic M (2010)	1
TP53	0	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDK1	0	POLA1	0	enzymatic study	Dehde S (2001)	1
CCNA2	1	TP53	0	pull down	Luciani MG (2000)	1
CREBBP	29	KAT2B	2	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Tini M (2002), Cho H (1998), Cho H (1998), Cho H (1998), Korzus E (1998), Korzus E (1998), Korzus E (1998), Yang XJ (1996), Yang XJ (1996), Yang XJ (1996)	10
SP1	0	CDK4	2	affinity chromatography technology	Tapias A (2008)	1
NFYA	2	TAF6	4	pull down	Frontini M (2002)	1
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
CDKN1A	1	TXNDC11	1	two hybrid	Wang J (2011)	1
NFYB	2	TP73	2	affinity chromatography technology, affinity chromatography technology	Hackzell A (2002), Uramoto H (2004)	2
TAF6	4	HDAC2	1	affinity chromatography technology	Nakamura T (2002)	1
SAMHD1	3	SKP2	2	affinity chromatography technology, affinity chromatography technology	St Gelais C (2014), St Gelais C (2014)	2
TP53	0	PSMD4	1	affinity chromatography technology, pull down	Kulikov R (2010), Sparks A (2014)	2
RPA1	0	ORC2	0	two hybrid, two hybrid	Kneissl M (2003), Kneissl M (2003)	2
CCNA2	1	ELMSAN1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	4
EP300	36	ORC2	0	pull down	Karmakar S (2010)	1
CCNA2	1	CDK2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Naderi S (2005), Varshochi R (2005), Di Fiore B (2010), Mateo F (2009), Abbas T (2007), Schulman BA (1998), Datta NS (1998), Wu G (1997), Sebastian B (1993), Liu S (2009), Ciarallo S (2002), Wolthuis R (2008), Vicent GP (2011), Zhang H (1995), Sayle KL (2003), Jeffrey PD (1995), Davies TG (2001), Cook A (2002), Pevarello P (2006), Levkau B (1998), Poon RY (1996), OConnor PM (1993), Davies TG (2002), Kontopidis G (2003), Andrews MJ (2004), Pevarello P (2004), Pevarello P (2005), Varjosalo M (2013), Varjosalo M (2013), Kikuchi R (2014), Kikuchi R (2014), Mateo F (2009), So J (2015), Okamoto K (2002), Song MS (2011), Huttlin EL (2015), Di Fiore B (2015), Pan ZQ (1993), Pan ZQ (1993), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	43
RBL2	5	SKP1	0	affinity chromatography technology	Bhattacharya S (2003)	1
CDC20	1	E2F1	0	affinity chromatography technology, affinity chromatography technology	Nath S (2014), Peart MJ (2010)	2
DYRK1B	1	CCNA2	1	affinity chromatography technology	Varjosalo M (2013)	1
CDK2	0	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study	Ruffner H (1999), Ruffner H (1999), Ruffner H (1999), Wang H (1997), Chen Y (1996)	5
DTNBP1	1	TRAF3IP1	3	two hybrid, affinity chromatography technology	Camargo LM (2007), Boldt K (2016)	2
CTNNB1	30	HERC5	2	affinity chromatography technology, affinity chromatography technology	Lee JH (2010), Park YS (2017)	2
CDC6	0	ORC1	3	two hybrid, two hybrid, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, pull down	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Saha P (1998), Saha P (1998), Saha P (1998), Ramachandran N (2004)	7
CDK4	2	RBL2	5	enzymatic study	Anders L (2011)	1
KAT2B	2	CDKN1B	1	pull down, affinity chromatography technology, pull down, enzymatic study	Perez-Luna M (2012), Perez-Luna M (2012), Perez-Luna M (2012), Perez-Luna M (2012)	4
CDK2	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
HDAC2	1	ELMSAN1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Joshi P (2013), Hein MY (2015)	3
CCNA2	1	HIST1H1B	4	enzymatic study, enzymatic study	Esashi F (2005), Poon RY (1996)	2
SP1	0	SKP2	2	affinity chromatography technology	Tapias A (2008)	1
CDK2	0	RBL2	5	enzymatic study, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shanahan F (1999), Lacy S (1997), Zhao J (1998), Varjosalo M (2013), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Howard CM (2000), Huttlin EL (2017)	9
8339	0	CCNA2	1	bioid	Lambert JP (2015)	1
CALM1	0	CCNA2	1	pull down	Cifuentes E (2004)	1
RPA1	0	CDK7	0	affinity chromatography technology	Marechal A (2014)	1
CDC25A	2	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Donzelli M (2004), Busino L (2003), Donzelli M (2002), He N (2005), Li X (2016), Yadav L (2017), Yadav L (2017)	7
POLA1	0	RB1	2	affinity chromatography technology, biochemical	Takemura M (1997), Takemura M (1997)	2
RBL2	5	CUL1	7	affinity chromatography technology	Bhattacharya S (2003)	1
CCNA2	1	P3H2	2	affinity chromatography technology	Hein MY (2015)	1
CDK3	0	SKP1	0	affinity chromatography technology	Varjosalo M (2013)	1
ORC2	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Matsuoka S (2007), Hill SJ (2014)	2
ORC1	3	CCNA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mendez J (2002), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
CUL1	7	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
PHF8	6	CDC20	1	affinity chromatography technology, affinity chromatography technology	Lim HJ (2013), Lim HJ (2013)	2
CKS2	0	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radulovic M (2010), Varjosalo M (2013), So J (2015), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
CDK3	0	RB1	2	enzymatic study, enzymatic study	Connell-Crowley L (1997), Ren S (2004)	2
PLA2G4A	1	CCNA2	1	affinity chromatography technology	Movahedi Naini S (2015)	1
SKP2	2	137529	0	pull down, affinity chromatography technology	Wang W (2004), Calvisi DF (2009)	2
CDKN1A	1	CDK6	0	affinity chromatography technology, pull down, affinity chromatography technology	Selma Dagtas A (2010), Ramachandran N (2004), Huttlin EL (2017)	3
SP1	0	SRRT	5	affinity chromatography technology	Chuang JY (2012)	1
CDK1	0	RPA1	0	enzymatic study, enzymatic study	Pan ZQ (1993), Pan ZQ (1993)	2
COPS6	0	SKP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
CALM1	0	KRAS	1	affinity chromatography technology, pull down, pull down, two hybrid	Villalonga P (2001), Villalonga P (2001), Sidhu RS (2003), Sidhu RS (2003)	4
SKP2	2	CDC20	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cen B (2010), Bashir T (2004), Kelly A (2014), Craney A (2016), Huttlin EL (2017)	5
KAT2B	2	CCNA2	1	affinity chromatography technology, pull down, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
CDK5	0	HIST1H1B	4	enzymatic study	Vincent I (2001)	1
ARID4A	3	CCNA2	1	enzymatic study	Suryadinata R (2011)	1
TP53	0	CDK5	0	affinity chromatography technology, pull down, affinity chromatography technology	Lee JH (2007), Lee JH (2007), Lee JH (2007)	3
FZR1	1	CDK4	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ANAPC4	0	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
ARID4A	3	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lai A (1999), Lai A (1999), Lai A (2001), Lai A (2001), Suryadinata R (2011), Suryadinata R (2011)	6
SMTNL2	3	CCNA2	1	affinity chromatography technology	Huttlin EL (2017)	1
CDK1	0	CDKN1B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Radu M (2008), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
HERC5	2	TP53	0	affinity chromatography technology	Huang YF (2014)	1
CDC27	2	PCNA	0	affinity chromatography technology	Williamson A (2011)	1
SP1	0	CALM1	0	affinity chromatography technology	Chuang JY (2012)	1
RAD23A	1	BRCA2	6	affinity chromatography technology	Chen L (2006)	1
COPS5	0	CDK4	2	affinity chromatography technology	Bennett EJ (2010)	1
CDC6	0	CCNA2	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Petersen BO (1999), Petersen BO (1999), Saha P (1998), Jiang W (1999)	4
EP300	36	CDK2	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Felzien LK (1999), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	4
CTNNB1	30	SKP1	0	affinity chromatography technology, unspecified method, affinity chromatography technology, imaging technique	Matsuzawa SI (2001), Winston JT (1999), Wang D (2011), Chen TC (2014)	4
CDK6	0	CDKN1C	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CKS1B	0	CDKN1B	1	enzymatic study, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology	Wang W (2003), Sitry D (2002), Zhou W (2009), Ooi LC (2013), Huttlin EL (2017)	5
CDK2	0	FZR1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Sorensen CS (2001), Fukushima H (2013), Lau AW (2013), Chang L (2015), Huttlin EL (2017)	5
ARID4A	3	RBL1	1	affinity chromatography technology	Lai A (1999)	1
SKP2	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2003), Min KW (2003), Lisztwan J (1998), Lisztwan J (1998), Marti A (1999), Zheng N (2002), Menon S (2008), Chew EH (2007), Chew EH (2007), Ji P (2006), Sabile A (2006), Tan P (1999), Lin HK (2009), Nie L (2011), Chua YS (2011), Huang Z (2004), Wu J (2012), Koyama-Nasu R (2007), Bashir T (2010), Saiga T (2009), Choo YY (2011), Jonason JH (2007), Jonason JH (2007), Bennett EJ (2010), Michel JJ (1998), Carrano AC (1999), Lyapina SA (1998), Lyapina SA (1998), Wu J (2012), Yu ZK (1998), Yu ZK (1998), Rodier G (2008), Swarnalatha M (2013), Cordero-Espinoza L (2013), Yumimoto K (2013), Chung FZ (2014), Zhou W (2014), Zhou W (2014), Yumimoto K (2012), Zhang S (2016), Zhang S (2016), Huttlin EL (2017), Kuchay S (2017), Reitsma JM (2017), Reitsma JM (2017), Ma X (2017)	46
SKP2	2	E2F1	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Marti A (1999), Marti A (1999), Zhang Z (2005), Farhana L (2002), Salon C (2007), Swarnalatha M (2013)	6
COPS5	0	CCNA2	1	affinity chromatography technology	Bennett EJ (2010)	1
FZR1	1	CKS1B	0	affinity chromatography technology	Bashir T (2004)	1
COPS6	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
DYRK1A	36	RB1	2	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Varjosalo M (2013)	3
CDK2	0	NFYB	2	affinity chromatography technology, affinity chromatography technology	Yun J (2003), Yun J (2003)	2
8339	0	BRCA1	7	bioid	Lambert JP (2015)	1
FZR1	1	BUB1B	0	enzymatic study, pull down	Tian W (2012), Diaz-Martinez LA (2015)	2
FXR1	0	SKP1	0	affinity chromatography technology	Qie S (2017)	1
CDK5	0	CCNA2	1	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2017)	2
CDKN1A	1	RBL2	5	affinity chromatography technology	Fogeron ML (2013)	1
CKS1B	0	CDT1	2	affinity chromatography technology	Huttlin EL (2017)	1
CDC27	2	MAD2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wassmann K (1998), Kallio M (1998), Li Y (1997), Li Y (1997), Lara-Gonzalez P (2011), Mansfeld J (2011), Visconti R (2010), Ma HT (2011), Sironi L (2001), Tipton AR (2011), Tipton AR (2011), Westhorpe FG (2011), Eytan E (2013), Lara-Gonzalez P (2011), Yen AH (2010), Hein MY (2015), Craney A (2016), Sedgwick GG (2016)	18
DYRK1A	36	RBL2	5	affinity chromatography technology	Varjosalo M (2013)	1
ORC1	3	CDK2	0	affinity chromatography technology, enzymatic study	Mendez J (2002), Mendez J (2002)	2
CDK2	0	PRC1	4	enzymatic study	Jiang W (1998)	1
COPS5	0	CCNA1	3	affinity chromatography technology	Bennett EJ (2010)	1
KAT2B	2	HIST1H1B	4	enzymatic study	Brand M (1999)	1
CCNA2	1	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Henneke G (2003), Huttlin EL (2015), Huttlin EL (2017)	3
CDK2	0	CDK3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	3
CCNA2	1	TP73	2	enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Gaiddon C (2003), Gaiddon C (2003), Gaiddon C (2003), Gaiddon C (2003)	4
PHF8	6	ANAPC4	0	affinity chromatography technology	Lim HJ (2013)	1
CDC6	0	POLA1	0	biochemical	Wan C (2015)	1
RPA1	0	CUL1	7	affinity chromatography technology	Marechal A (2014)	1
PSMA6	1	CCNA2	1	affinity chromatography technology	Sharma SS (2011)	1
CCNQ	0	BIRC6	15	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP37	1	TAF6	4	bioid	Yeh C (2015)	1
ELMSAN1	4	EIF2AK2	1	affinity chromatography technology	Hein MY (2015)	1
CDC6	0	ORC2	0	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Mendez J (2000), Ramachandran N (2004)	5
FANCC	0	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Dao KH (2012), Dao KH (2012), Huard CC (2014), Huard CC (2014), Huard CC (2014)	5
NFYA	2	TAF11	0	pull down	Frontini M (2002)	1
RB1	2	E2F1	0	affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Nicolas E (2001), Pardo PS (2002), Choubey D (1996), Fajas L (2000), Dyson N (1993), Dyson N (1993), Wu CL (1995), Taniura H (1998), Dai Y (2003), Fedele M (2006), Fedele M (2006), Brown VD (2002), De Blasio A (2005), Chau CM (2008), Dasgupta P (2004), Yang L (2011), Kruetzfeldt M (2005), Harbour JW (1999), Lee SJ (1998), Gao D (2009), Delston RB (2011), Gupta K (2000), Sdek P (2004), Flemington EK (1993), Chang YH (2012), Inoue Y (2007), Inoue Y (2007), Inoue Y (2007), Liu X (2006), Moberg K (1996), Knudsen ES (1996), Brown VD (1999), Brown VD (1999), Whitaker LL (1998), Whitaker LL (1998), Hagemeier C (1993), Bhat UG (1999), Xiao B (2003), Xiao B (2003), Vidal M (1996), Markham D (2006), Markham D (2006), Ianari A (2009), Ianari A (2009), Dhillon NK (2002), Knudsen ES (1997), Knudsen ES (1997), Gery S (2004), Gery S (2004), Kashuba E (2008), Kashuba E (2008), Pearson A (1997), Ginsberg D (1994), Welch PJ (1995), Wang J (2009), Aoki I (2012), Trimarchi JM (1998), Kumari A (2015), Gamell C (2017), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	63
E2F1	0	CDKN1A	1	imaging technique	Devgan V (2005)	1
E2F1	0	SP1	0	affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down	Lin SY (1996), Lin SY (1996), Rotheneder H (1999), Rotheneder H (1999), Karlseder J (1996), Karlseder J (1996), Doetzlhofer A (1999)	7
CDH2	4	CCNA2	1	affinity chromatography technology	Wan L (2011)	1
KAT2B	2	CDK2	0	pull down, affinity chromatography technology, enzymatic study	Mateo F (2009), Mateo F (2009), Mateo F (2009)	3
TP73	2	RB1	2	affinity chromatography technology	Ozaki T (2003)	1
FZR1	1	TRIM33	4	affinity chromatography technology	Sedgwick GG (2012)	1
CDKN1B	1	CUL1	7	unspecified method, pull down	Carrano AC (1999), Enchev RI (2012)	2
CUL1	7	E2F1	0	affinity chromatography technology, pull down	Marti A (1999), Marti A (1999)	2
PCNA	0	CDC6	0	two hybrid	Saha P (1998)	1
UHRF2	1	RPA1	0	affinity chromatography technology	Lai M (2016)	1