Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
RUNX1 861 METHACHOLINE CHLORIDE CHEMBL1200764 PharmGKB
RUNX1 861 DIPHENHYDRAMINE HYDROCHLORIDE CHEMBL1620 CKB 26837761
RUNX1 861 CYTARABINE CHEMBL803 CIViC 21343560
RUNX1 861 DOXORUBICIN CHEMBL53463 CKB 26552700

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
RUNX1 rs11702779 AA methacholine chloride other yes This is for children without prenatal tobacco exposure. Genotype AA is associated with increased response to methacholine chloride in children with Asthma as compared to genotypes AG + GG. 21803869 827788970
RUNX1 rs11702779 AG + GG methacholine chloride other yes This is for children who WERE exposed to maternal smoking in utero. Genotypes AG + GG are associated with increased response to methacholine chloride in children with Asthma. 21803869 827789050