PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CHD4	22	CHD3	19	affinity chromatography technology, affinity chromatography technology, biochemical	Xue Y (1998), Xue Y (1998), Havugimana PC (2012)	3
MTA1	3	CHD3	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yan C (2003), Khaleque MA (2008), Xue Y (1998), Wan C (2015)	4
GATAD2B	15	CDK2AP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CHD4	22	GATAD2A	3	affinity chromatography technology, biochemical, affinity chromatography technology	Rahman S (2011), Havugimana PC (2012), Huttlin EL (2017)	3
MBD2	1	SIN3A	13	pull down, two hybrid	Boeke J (2000), Boeke J (2000)	2
ZNF219	3	MBD2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ZNF219	3	ZBTB2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD2	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brackertz M (2002), Ng HH (1999), Ng HH (1999), Ng HH (1999), Zhang Y (1999), Zhang Y (1999), Feng Q (2001), Humphrey GW (2001), Humphrey GW (2001), Godmann M (2007), Bantscheff M (2011), Joshi P (2013), Fujita H (2003), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	16
MTA2	1	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Zhang Y (1998), Wang Y (2009), Cui S (2011), Havugimana PC (2012), Quan J (2014), Wan C (2015)	8
ZNF219	3	MBD3	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CHD4	22	GATAD2B	15	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rahman S (2011), Huttlin EL (2015), Huttlin EL (2017)	3
MTA1	3	ZNF521	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA3	3	RBBP4	3	affinity chromatography technology, biochemical, affinity chromatography technology	Bantscheff M (2011), Wan C (2015), Hauri S (2016)	3
HDAC1	4	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yao YL (2003), Yao YL (2003), Yao YL (2003), Mazumdar A (2001), Mazumdar A (2001), Yoo YG (2006), Liu XF (2004), Khaleque MA (2008), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Millard CJ (2016), Millard CJ (2016)	21
CDK2AP1	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016)	5
RBBP4	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Hakimi MA (2003), Zhang Y (2002), Tong JK (1998), Sun JM (2007), Sun JM (2007), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Wan C (2015), Hauri S (2016)	14
MBD3	4	GATAD2B	15	pull down, pull down, affinity chromatography technology, imaging technique, pull down, two hybrid, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology	Brackertz M (2002), Feng Q (2002), Feng Q (2002), Feng Q (2002), Gong Z (2006), Rolland T (2014), Huttlin EL (2015), Wan C (2015), Yu H (2011), Huttlin EL (2017)	10
CDK2AP1	1	MTA1	3	affinity chromatography technology	Hein MY (2015)	1
MBD2	1	CHD3	19	pull down, affinity chromatography technology	Zhang Y (1999), Feng Q (2001)	2
ZNF219	3	GATAD2B	15	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HDAC1	4	ZNF521	3	affinity chromatography technology, affinity chromatography technology	Joshi P (2013), Huttlin EL (2017)	2
RBBP7	1	GATAD2B	15	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Feng Q (2002), Feng Q (2002), Gong Z (2006), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	6
MBD3	4	MBD2	1	two hybrid, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, pull down, affinity chromatography technology	Jiang CL (2004), Zhang Y (1999), Tatematsu KI (2000), Tatematsu KI (2000), Tatematsu KI (2000), Tatematsu KI (2000), Jin SG (2005), Jin SG (2005), Jin SG (2005), Feng Q (2001)	10
GATAD2B	15	GATAD2A	3	biochemical	Wan C (2015)	1
MTA1	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Mazumdar A (2001), Mazumdar A (2001), Mazumdar A (2001), Li DQ (2010), Yan C (2003), Balasenthil S (2007), Ohshiro K (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	16
MBD2	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Brackertz M (2002), Ng HH (1999), Zhang Y (1999), Angrisano T (2006), Feng Q (2001), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	8
RBBP4	3	BCL11A	14	affinity chromatography technology	Hauri S (2016)	1
HDAC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Yao YL (2003), Fleischer TC (2003), Fleischer TC (2003), Yang L (2003), Grozinger CM (1999), Zhang J (2002), Zhang J (2002), You A (2001), Zhang Y (1999), Zhang Y (2002), Tong JK (1998), Hassig CA (1998), Yasui D (2002), Huang EY (2000), Huang EY (2000), Kuzmichev A (2002), Kuzmichev A (2002), Martinowich K (2003), Martinowich K (2003), Suzuki M (2003), Suzuki M (2006), Nakamura T (2002), Wei Q (2005), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Skowyra D (2001), Humphrey GW (2001), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Oh YM (2009), Wan C (2015), Hein MY (2015), Hsu DS (2014), Huttlin EL (2017)	45
RBBP4	3	GATAD2B	15	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Feng Q (2002), Feng Q (2002), Gong Z (2006), Huttlin EL (2017), Hauri S (2016)	5
MBD3	4	CHD4	22	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sakai H (2002), Cui S (2011), Havugimana PC (2012), Quan J (2014)	4
RBBP7	1	GATAD2A	3	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gong Z (2006), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	5
CDK2AP1	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Bantscheff M (2011), Joshi P (2013), Hein MY (2015)	4
CHD4	22	MTA3	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Kwintkiewicz J (2011), Kwintkiewicz J (2011), Bantscheff M (2011), Wan C (2015)	4
MBD3	4	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Sakai H (2002), Noh EJ (2009), Noh EJ (2009), Sun JM (2007), Adenuga D (2010), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	9
MBD3L1	0	SIN3A	13	affinity chromatography technology	Jiang CL (2004)	1
ZNF219	3	CDK2AP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	3
CHD3	19	RBBP4	3	affinity chromatography technology, biochemical, affinity chromatography technology	Xue Y (1998), Havugimana PC (2012), Hauri S (2016)	3
MBD3L1	0	BEND7	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
MTA3	3	CHD3	19	affinity chromatography technology, biochemical	Fujita N (2003), Wan C (2015)	2
MTA3	3	GATAD2B	15	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Bantscheff M (2011), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
ZNF219	3	BEND7	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	GNB4	2	affinity chromatography technology	Huttlin EL (2015)	1
MBD3L1	0	CHD3	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
CHD3	19	RBBP7	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	4
MBD3L1	0	MBD2	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Jiang CL (2004), Jiang CL (2004), Jiang CL (2004)	4
HDAC2	1	GATAD2A	3	biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013)	3
SIN3A	13	MBD3	4	affinity chromatography technology	Nakamura T (2002)	1
RBBP7	1	ZBTB2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA1	3	SIN3A	13	affinity chromatography technology	Yao YL (2003)	1
CHD4	22	RBBP4	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Wan C (2015), Hauri S (2016)	9
CHD4	22	SIN3A	13	affinity chromatography technology	Zhang Y (1998)	1
MTA3	3	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	4
MTA3	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Fujita N (2003), Kwintkiewicz J (2011), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	8
ZNF219	3	CHD3	19	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBBP7	1	ZNF423	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	ZNF423	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBBP4	3	RBBP7	1	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	7
ZNF219	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA3	3	MBD3	4	affinity chromatography technology, biochemical	Fujita N (2003), Wan C (2015)	2
RBBP4	3	ZNF296	1	affinity chromatography technology	Hauri S (2016)	1
MBD2	1	MTA2	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Zhang Y (1999), Feng Q (2001), Feng Q (2001), Humphrey GW (2001), Humphrey GW (2001), Wan C (2015)	6
MTA1	3	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Roche AE (2008), Huttlin EL (2015), Huttlin EL (2017), Millard CJ (2016), Hauri S (2016)	6
MBD3	4	RBBP7	1	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1999), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	5
CDK2AP1	1	MBD2	1	affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Hein MY (2015)	2
SIN3A	13	CHD3	19	affinity chromatography technology	Nakamura T (2002)	1
MTA1	3	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Xue Y (1998), Cui S (2011), Cui S (2011), Chudnovsky Y (2014), Wan C (2015)	6
RBBP7	1	BCL11A	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	3
ZNF219	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
CDK2AP1	1	CHD4	22	affinity chromatography technology	Hein MY (2015)	1
MTA2	1	CHD3	19	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Zhang Y (1999), Feng Q (2001), Wang Y (2009), Havugimana PC (2012), Wan C (2015)	5
BCL11A	14	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cismasiu VB (2005), Joshi P (2013), Huttlin EL (2017)	3
MBD3	4	MTA1	3	pull down, affinity chromatography technology, biochemical	Yildirim O (2011), Cui S (2011), Wan C (2015)	3
MBD2	1	GATAD2A	3	affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology	Brackertz M (2002), Brackertz M (2002), Brackertz M (2006), Wan C (2015), Huttlin EL (2017)	5
MTA2	1	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Cui S (2011), Wan C (2015)	4
CHD4	22	RBBP7	1	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Havugimana PC (2012), Huttlin EL (2015), Quan J (2014), Huttlin EL (2017)	7
MTA3	3	CDK2AP1	1	affinity chromatography technology, affinity chromatography technology	Bantscheff M (2011), Hein MY (2015)	2
CHD3	19	GATAD2A	3	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
MTA3	3	GATAD2A	3	affinity chromatography technology, biochemical, affinity chromatography technology	Bantscheff M (2011), Wan C (2015), Huttlin EL (2017)	3
GATAD2B	15	MTA2	1	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Feng Q (2002), Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	5
MBD2	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Feng Q (2001), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	4
MBD3L1	0	BCL11A	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HDAC1	4	ZBTB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	3
MTA3	3	MTA1	3	biochemical	Wan C (2015)	1
MBD3L1	0	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
MTA1	3	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, x-ray crystallography, unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology	Yao YL (2003), Roche AE (2008), Cui S (2011), Cui S (2011), Rolland T (2014), Huttlin EL (2015), Alqarni SS (2014), Alqarni SS (2014), Alqarni SS (2014), Wan C (2015), Huttlin EL (2017), Millard CJ (2016), Millard CJ (2016), Millard CJ (2016), Hauri S (2016)	15
RBBP4	3	GATAD2A	3	pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Gong Z (2006), Havugimana PC (2012), Huttlin EL (2017), Hauri S (2016)	4
CDK2AP1	1	CHD3	19	affinity chromatography technology	Hein MY (2015)	1
GATAD2B	15	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Feng Q (2002), Bantscheff M (2011), Joshi P (2013), Huttlin EL (2015), Huttlin EL (2017)	5
ZNF219	3	RBBP7	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ZNF219	3	ZNF521	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	MTA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
ZNF219	3	MTA3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
BCL11A	14	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cismasiu VB (2005), Huttlin EL (2015), Huttlin EL (2017)	3
GATAD2B	15	CHD3	19	affinity chromatography technology, biochemical, affinity chromatography technology	Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	3
MBD3L1	0	CHD4	22	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ZNF219	3	ZNF423	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBBP7	1	SIN3A	13	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (1998), Kuzmichev A (2002), Nakamura T (2002), Huttlin EL (2015), Huttlin EL (2017), Hauri S (2016)	6
MTA1	3	ZNF423	14	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HDAC1	4	GATAD2A	3	pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gong Z (2006), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	6
ZNF219	3	MTA2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA1	3	GATAD2B	15	biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Havugimana PC (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	4
BCL11A	14	MBD3	4	affinity chromatography technology	Cismasiu VB (2005)	1
HDAC1	4	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Yao YL (2003), Grozinger CM (1999), Tong JK (1998), Tong JK (1998), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Terhune SS (2010), Polo SE (2010), Xue Y (1998), Xue Y (1998), Xue Y (1998), Kwintkiewicz J (2011), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Quan J (2014), Wan C (2015), Hein MY (2015), Weiss K (2016), Huttlin EL (2017)	28
MBD2	1	GATAD2B	15	pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Brackertz M (2002), Feng Q (2002), Feng Q (2002), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	6
MBD3	4	HDAC1	4	affinity chromatography technology, biochemical, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sakai H (2002), Zhang Y (1999), Zhang Y (1999), Saito M (2002), Noh EJ (2009), Noh EJ (2009), Le Guezennec X (2006), Humphrey GW (2001), Sun JM (2007), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	16
MBD3L1	0	ZNF521	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	ZBTB2	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDK2AP1	1	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Hein MY (2015), Hauri S (2016)	3
MTA2	1	RBBP7	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Yao YL (2003), Zhang Y (1999), Feng Q (2001), Wang Y (2009), Fu J (2011), Havugimana PC (2012), Huttlin EL (2015), Huttlin EL (2017), Brasen C (2017), Brasen C (2017), Hauri S (2016)	11
MTA3	3	MTA2	1	affinity chromatography technology, biochemical	Bantscheff M (2011), Wan C (2015)	2
RBBP4	3	BEND7	0	affinity chromatography technology	Hauri S (2016)	1
HDAC2	1	RBBP7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Hakimi MA (2003), Adenuga D (2010), Xue Y (1998), Havugimana PC (2012), Bantscheff M (2011), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Hauri S (2016)	9
ZNF219	3	RBBP4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3	4	MTA2	1	affinity chromatography technology, biochemical, pull down, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Sakai H (2002), Zhang Y (1999), Zhang Y (1999), Saito M (2002), Feng Q (2001), Wang Y (2009), Havugimana PC (2012), Wan C (2015)	8
GTF2IRD1	6	MBD3L1	0	two hybrid, affinity chromatography technology	Carmona-Mora P (2015), Carmona-Mora P (2015)	2
BCL11A	14	MTA2	1	affinity chromatography technology	Cismasiu VB (2005)	1
GATAD2A	3	MTA1	3	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
SIN3A	13	RBBP4	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hassig CA (1997), Zhang Y (1998), Nakamura T (2002), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Bantscheff M (2011), Hauri S (2016)	8
MBD3L1	0	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
HDAC1	4	CHD3	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tong JK (1998), Tong JK (1998), Kuzmichev A (2002), Sun JM (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Xue Y (1998), Havugimana PC (2012), Joshi P (2013), Hein MY (2015), Huttlin EL (2017)	12
CDK2AP1	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Bantscheff M (2011), Joshi P (2013), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	6
MBD3L1	0	MBD3	4	two hybrid, two hybrid, pull down, affinity chromatography technology	Jiang CL (2004), Jiang CL (2004), Jiang CL (2004), Jiang CL (2004)	4
HDAC2	1	CHD3	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Hakimi MA (2003), Tong JK (1998), Tong JK (1998), Hakimi MA (2002), Sun JM (2007), Xue Y (1998), Xue Y (1998), Xue Y (1998), Havugimana PC (2012), Joshi P (2013)	10
HDAC2	1	BCL11A	14	affinity chromatography technology	Joshi P (2013)	1
CDK2AP1	1	MTA2	1	affinity chromatography technology	Hein MY (2015)	1
MBD3L1	0	MTA3	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	CDK2AP1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RBBP7	1	ZNF296	1	affinity chromatography technology	Hauri S (2016)	1
HDAC2	1	CHD4	22	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Hakimi MA (2003), Schmidt DR (1999), Schmidt DR (1999), Tong JK (1998), Tong JK (1998), Tong JK (1998), ONeill DW (2000), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Xue Y (1998), Xue Y (1998), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	17
RBBP7	1	ZNF521	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	ZNF219	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA2	1	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical	Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Zhang Y (1999), Banach-Orlowska M (2009), Feng Q (2001), Humphrey GW (2001), Humphrey GW (2001), Wang Y (2009), Fu J (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	14
MBD3L1	0	MTA1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
MBD3L1	0	GATAD2B	15	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA2	1	RBBP4	3	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, x-ray crystallography, affinity chromatography technology	Yao YL (2003), Zhang Y (1999), Banach-Orlowska M (2009), Pflum MK (2001), Feng Q (2001), Wang Y (2009), Cui S (2011), Havugimana PC (2012), Wan C (2015), Brasen C (2017), Brasen C (2017), Brasen C (2017), Hauri S (2016)	13
HDAC1	4	RBBP7	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Ng HH (1999), Zhang Y (1999), Zhang Y (1997), Banach-Orlowska M (2009), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Xue Y (1998), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Yeh HH (2015), Yeh HH (2015), Huttlin EL (2017), Hauri S (2016)	19
RBBP4	3	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Nicolas E (2001), Nicolas E (2001), Grozinger CM (1999), You A (2001), Hassig CA (1997), Hassig CA (1997), Ng HH (1999), Zhang Y (1999), Zhang Y (2002), Hassig CA (1998), Zhang Y (1997), Banach-Orlowska M (2009), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Humphrey GW (2001), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Xue Y (1998), Cui S (2011), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Hauri S (2016)	35
HDAC1	4	MTA2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Yao YL (2003), You A (2001), Zhang Y (1999), Zhang Y (1999), Yasui D (2002), Banach-Orlowska M (2009), Banach-Orlowska M (2009), Cui Y (2006), Pflum MK (2001), Feng Q (2001), Humphrey GW (2001), Humphrey GW (2001), Humphrey GW (2001), Zhang Y (1998), Terhune SS (2010), Opsahl JA (2010), Wang Y (2009), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Joshi P (2013), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	27
MBD2	1	RBBP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ng HH (1999), Feng Q (2001), Hauri S (2016)	3
CDK2AP1	1	MBD3	4	affinity chromatography technology, affinity chromatography technology	Spruijt CG (2010), Hein MY (2015)	2
CHD3	19	MBD3	4	biochemical	Havugimana PC (2012)	1
ZNF219	3	MTA1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA2	1	GATAD2A	3	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
MTA3	3	HDAC2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Fujita N (2003), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Wan C (2015)	5
MBD3	4	GATAD2A	3	pull down, pull down, biochemical, biochemical, affinity chromatography technology	Brackertz M (2002), Gong Z (2006), Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	5
MBD3L1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jiang CL (2004), Huttlin EL (2015), Huttlin EL (2017)	3
MBD2	1	MTA1	3	biochemical	Wan C (2015)	1
GATAD2B	15	HDAC1	4	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Feng Q (2002), Gong Z (2006), Bantscheff M (2011), Joshi P (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
MBD3L1	0	ZNF296	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MTA2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology	Yao YL (2003), Pflum MK (2001)	2
CDK2AP1	1	ZBTB2	1	affinity chromatography technology	Hein MY (2015)	1
CDK2AP1	1	GATAD2A	3	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
ZNF219	3	GATAD2A	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3	4	RBBP4	3	pull down, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (1999), Cui S (2011), Havugimana PC (2012), Hauri S (2016)	4
MTA3	3	MBD2	1	affinity chromatography technology, biochemical	Bantscheff M (2011), Wan C (2015)	2
BCL11A	14	CHD4	22	affinity chromatography technology	Cismasiu VB (2005)	1
HDAC2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Fleischer TC (2003), Fleischer TC (2003), Hakimi MA (2003), Yang L (2003), Laherty CD (1997), Zhang Y (2002), Tong JK (1998), Zhang Y (2005), Nakamura T (2002), Sekhavat A (2007), Zou J (2004), Sun JM (2007), Xue Y (1998), Tsai SC (2002), Brandl A (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hsu DS (2014)	20
ZNF219	3	CHD4	22	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MBD3L1	0	GATAD2A	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2