PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
COPS3	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	9
HIST1H3A	3	DDB1	6	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
CUL5	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ehrlich ES (2009), Ehrlich ES (2009), Bennett EJ (2010)	3
CAND1	2	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
DTL	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Higa LA (2006), Higa LA (2006), Sertic S (2013), Shibata E (2014), Hein MY (2015), Shibata E (2011), Higa LA (2006), Higa LA (2006)	9
DCUN1D1	0	PHIP	20	affinity chromatography technology	Bennett EJ (2010)	1
DCAF8	1	COPS7A	0	biochemical	Kristensen AR (2012)	1
CUL5	1	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CDT1	2	GRWD1	3	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2015), Sugimoto N (2015), Sugimoto N (2015)	6
DDA1	1	DCAF8	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
RASSF1	3	LATS1	3	affinity chromatography technology	Guo C (2007)	1
COPS8	2	COPS7A	0	biochemical, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Huang X (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
DDA1	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Jin J (2006), Hein MY (2015)	3
DCAF1	5	CUL4A	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahn J (2010), Belzile JP (2007), He YJ (2006), McCall CM (2008), McCall CM (2008), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Kyei GB (2015)	14
DDB1	6	COPS6	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009)	5
WDTC1	1	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
SKP1	0	FBXW5	6	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lievens S (2009), Busino L (2012), Watanabe N (2004), Jeong YT (2013), Tian X (2015), Hauri S (2016)	6
SLBP	0	DCAF11	2	pull down, affinity chromatography technology, affinity chromatography technology	Djakbarova U (2016), Djakbarova U (2016), Djakbarova U (2016)	3
ATXN3	2	CHEK1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Tu Y (2017), Tu Y (2017), Tu Y (2017), Tu Y (2017), Tu Y (2017)	5
DCUN1D1	0	COPS3	1	affinity chromatography technology	Bennett EJ (2010)	1
SLBP	0	CUL4A	2	pull down, affinity chromatography technology, affinity chromatography technology	Djakbarova U (2016), Djakbarova U (2016), Djakbarova U (2016)	3
CUL4A	2	COMMD1	1	pull down, pull down	Mao X (2011), Mao X (2011)	2
MRPS11	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL4A	2	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Ito T (2010), Bennett EJ (2010), Liu Y (2015), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	14
MDM2	2	ERCC8	1	affinity chromatography technology	Latini P (2011)	1
GPS1	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Stotland A (2012), Huang X (2005), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
COPS2	5	DCAF4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
HSP90AA1	7	SKP1	0	pull down	Zhang M (2008)	1
MRPS11	1	DDA1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS6	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
COPS8	2	DCAF4	3	affinity chromatography technology	Huttlin EL (2017)	1
CUL4B	8	DCAF16	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF4L2	3	COPS2	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Wang H (2016)	2
CUL4A	2	MDM2	2	affinity chromatography technology, affinity chromatography technology	Banks D (2006), Latini P (2011)	2
CUL4A	2	GLMN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tron AE (2012), Tron AE (2012), Huttlin EL (2017)	3
GRK5	7	HSP90AA1	7	affinity chromatography technology	Wu Z (2012)	1
COPS3	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
COPS5	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	11
COPS7A	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015), Huttlin EL (2017)	3
DDB1	6	WDTC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Huttlin EL (2017)	4
DDB1	6	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006)	2
COPS4	0	COPS7B	0	affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
COPS4	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
CDKN1A	1	EEF1A1	0	two hybrid	Vinayagam A (2011)	1
DDB1	6	DCAF10	2	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006)	2
DCUN1D4	0	CUL4B	8	pull down, enzymatic study	Monda JK (2013), Monda JK (2013)	2
CUL5	1	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017), Zhu Z (2017)	3
HOXA9	0	CUL4A	2	affinity chromatography technology, pull down	Zhang Y (2003), Zhang Y (2003)	2
CAND1	2	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Jin J (2006), Wang H (2006), Higa LA (2006), Higa LA (2006), Kawajiri K (2009), Bennett EJ (2010), Havugimana PC (2012), Ji Q (2014), Wan C (2015), Hein MY (2015), Mo Y (2017), Mo Y (2017), Yang Y (2015), Yang Y (2015), Yang Y (2015), Higa LA (2006), Higa LA (2006), Ohtake F (2007), Ohtake F (2007), Ohtake F (2007)	23
COPS7A	0	DCAF4	3	affinity chromatography technology	Hein MY (2015)	1
DDB1	6	COPS2	5	affinity chromatography technology, affinity chromatography technology, pull down	Angers S (2006), Jin J (2006), Emberley ED (2012)	3
RNF7	0	GLMN	2	pull down	Tron AE (2012)	1
HIST1H1A	0	DDB1	6	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
CUL5	1	COPS5	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
DCAF8	1	COPS2	5	affinity chromatography technology	Olma MH (2009)	1
CAND1	2	SKP1	0	affinity chromatography technology, affinity chromatography technology	Zheng J (2002), Bennett EJ (2010)	2
UBC	7	COPS4	0	affinity chromatography technology	Matsumoto M (2005)	1
EEF1A1	0	HSP90AA1	7	affinity chromatography technology	Aranda-Orgilles B (2008)	1
ASB4	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ferguson JE (2007), Andresen CA (2014), Andresen CA (2014)	3
DCUN1D1	0	CAND1	2	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bennett EJ (2010), Bommelje CC (2013), Kim AY (2008), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	11
UVRAG	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Yang Y (2016), Yang Y (2016)	2
GRK5	7	DCAF5	1	affinity chromatography technology	Wu Z (2012)	1
CUL5	1	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D2	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
UBC	7	GNB2	3	affinity chromatography technology	Matsumoto M (2005)	1
UBXN7	3	DCAF1	5	affinity chromatography technology	Alexandru G (2008)	1
DDB1	6	PHIP	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Angers S (2006), Jin J (2006), Jin J (2006), Wan C (2015)	4
COPS6	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
CDT1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology	Hu J (2004), Hu J (2004), Hu J (2004), Hu J (2004), Zhang Y (2012)	5
CRBN	2	COPS7B	0	affinity chromatography technology	Kroenke J (2014)	1
CUL4B	8	PHIP	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Jin J (2006), Hein MY (2015)	3
DDB1	6	UBC	7	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Matsumoto M (2005)	2
ATXN3	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Tu Y (2017), Tu Y (2017)	2
CUL5	1	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF11	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	3
DCUN1D2	0	CUL5	1	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
CUL4A	2	DCUN1D1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
HSP90AA1	7	DET1	2	affinity chromatography technology	Taipale M (2012)	1
ASB4	2	GPS1	1	affinity chromatography technology, affinity chromatography technology	Li JY (2007), Li JY (2007)	2
CUL5	1	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	ERCC8	1	affinity chromatography technology	Bennett EJ (2010)	1
NEDD8	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
DDB1	6	DCAF5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006)	3
ERCC8	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
GRK5	7	COPS7A	0	affinity chromatography technology	Wu Z (2012)	1
DCUN1D1	0	COPS6	0	affinity chromatography technology	Bennett EJ (2010)	1
PCNA	0	CHEK1	2	affinity chromatography technology	Scorah J (2008)	1
COPS3	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Enchev RI (2010), Olma MH (2009), Havugimana PC (2012), Huttlin EL (2015), Huang X (2016), Huttlin EL (2017)	6
DCUN1D1	0	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
MDM2	2	UBC	7	pull down, enzymatic study, enzymatic study	Higashitsuji H (2005), Luo J (2013), Poyurovsky MV (2007)	3
CUL4A	2	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Bennett EJ (2010), Sertic S (2013), Rossi M (2013), Jin J (2006), Shibata E (2011), Higa LA (2006)	7
CUL4A	2	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Bennett EJ (2010), Huttlin EL (2017)	4
HIST1H1C	2	RBX1	2	affinity chromatography technology, pull down	Kim K (2013), Kim K (2013)	2
CUL4A	2	DCAF16	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Jin J (2006)	3
DLC1	11	FBXW5	6	affinity chromatography technology, affinity chromatography technology	Kim TY (2013), Kim TY (2013)	2
RFWD2	0	DDB2	1	affinity chromatography technology	Olma MH (2009)	1
LIG1	4	DDB1	6	affinity chromatography technology, affinity chromatography technology	Peng Z (2016), Peng Z (2016)	2
DDB1	6	BRWD1	6	affinity chromatography technology, biochemical	Angers S (2006), Wan C (2015)	2
GRK5	7	GRWD1	3	affinity chromatography technology	Wu Z (2012)	1
DDA1	1	DCAF10	2	affinity chromatography technology	Olma MH (2009)	1
DET1	2	MDM2	2	affinity chromatography technology	Pick E (2007)	1
PCNA	0	LIG1	4	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Ohta S (2002), Montecucco A (1998), Han J (2014), Ferry L (2017)	4
COPS5	0	DCAF16	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF4L2	3	GPS1	1	affinity chromatography technology	Wang H (2016)	1
COPS2	5	COPS4	0	affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Huang X (2005), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	8
DTL	0	COPS2	5	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Higa LA (2006)	2
DDB1	6	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Min KW (2005), Emberley ED (2012), Olma MH (2009)	5
COPS5	0	GRWD1	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	BRWD1	6	affinity chromatography technology	Bennett EJ (2010)	1
DDB2	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, imaging technique	Kapetanaki MG (2006), Takedachi A (2010), Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Matsumoto S (2015), Hein MY (2015), Groisman R (2006), Groisman R (2006), Chitale S (2017)	10
COPS6	0	COPS4	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	14
COPS5	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Bennett EJ (2010), Oh W (2006), Chun Y (2013), Chun Y (2013), Chun Y (2013), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
COPS5	0	TOR1AIP2	2	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010)	2
DCUN1D5	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
DDA1	1	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009), Olma MH (2009), Huttlin EL (2017)	4
DET1	2	COPS5	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	CDT1	2	biochemical	He YJ (2006)	1
DCUN1D1	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Huttlin EL (2017), Boldt K (2016)	4
TUBG1	2	DDA1	1	affinity chromatography technology	Fogeron ML (2013)	1
DCAF8	1	COPS3	1	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
UBC	7	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography	Matsumoto M (2005), Bennett EJ (2010), Singh RK (2012), Singh RK (2012)	4
EEF1A1	0	HSPA1A	0	biochemical	Havugimana PC (2012)	1
COPS5	0	CAND1	2	biochemical, affinity chromatography technology	Bornstein G (2006), Bennett EJ (2010)	2
DDA1	1	DCAF15	3	affinity chromatography technology	Olma MH (2009)	1
DET1	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Wertz IE (2004), Vitari AC (2011), Lu G (2014), Lu G (2014), Pick E (2007), Huttlin EL (2017)	7
COPS8	2	COPS3	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Min KW (2005), Enchev RI (2010), Sharon M (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
DTL	0	TUBG1	2	biochemical	Pan HW (2006)	1
COPS5	0	PWP1	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS8	2	COPS2	5	biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Yang X (2002), Huang X (2005), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
CUL4A	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Pick E (2007), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006)	7
RBX1	2	CUL4B	8	affinity chromatography technology, biochemical, enzymatic study, affinity chromatography technology, imaging technique	Dias DC (2002), Ji Q (2014), Huang DT (2009), Hein MY (2015), Yang Y (2015)	5
NEDD8	0	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
UBC	7	CDKN1B	1	affinity chromatography technology	Huang G (2014)	1
DET1	2	COPS6	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
ERCC8	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down	Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Groisman R (2006)	8
CDKN1A	1	GNB2	3	two hybrid	Vinayagam A (2011)	1
MRPS11	1	WDTC1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DDB1	6	DCAF11	2	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Angers S (2006), Jin J (2006), He YJ (2006), Olma MH (2009), Jin J (2006), Huttlin EL (2017), Lo JY (2017)	8
COPS6	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	TOR1AIP2	2	affinity chromatography technology	Olma MH (2009)	1
UBXN7	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012)	2
COPS6	0	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
COPS6	0	TOR1AIP2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
CDT1	2	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Sugimoto N (2008), Sugimoto N (2008), Sugimoto N (2008), Senga T (2006), Hu J (2006), Arias EE (2006), Nishitani H (2006), Tsanov N (2014), Chandrasekaran S (2011), Coleman KE (2015), Higa LA (2006)	11
COPS5	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Sertic S (2013), Higa LA (2006), Higa LA (2006)	5
RFWD2	0	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
CUL5	1	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
UBXN7	3	SKP1	0	affinity chromatography technology	Alexandru G (2008)	1
CUL4A	2	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Angers S (2006), Hu J (2004), Chua YS (2011), Tron AE (2012), Zheng J (2002), He YJ (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Olma MH (2009), Olma MH (2009), Yang Y (2016), Yang Y (2016)	18
CUL4A	2	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Kapetanaki MG (2006), Matsuda N (2005), Higa LA (2006), Nag A (2001), Takedachi A (2010), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), Groisman R (2003), Groisman R (2003), Hrecka K (2007), Shiyanov P (1999), Shiyanov P (1999), Bennett EJ (2010), Kulaksiz G (2005), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Groisman R (2003), Huttlin EL (2015), Hein MY (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Fantini D (2017)	31
DLC1	11	DDB1	6	affinity chromatography technology	Kim TY (2013)	1
CAND1	2	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Yang X (2002), Enchev RI (2010), Huang X (2005), Kapelari B (2000), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Rozen S (2015), Huttlin EL (2017)	13
CRBN	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Xu Q (2016), Eichner R (2016), Huttlin EL (2017), Kroenke J (2014)	4
COPS3	1	HSP90AA1	7	affinity chromatography technology	Min KW (2005)	1
RBBP7	1	DDB1	6	affinity chromatography technology	Mouysset J (2015)	1
NEDD8	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	TOR1AIP2	2	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	COPS7B	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS4	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Shibata E (2011), Higa LA (2006)	3
DCAF1	5	RBX1	2	pull down	Ahn J (2010)	1
CUL4A	2	PWP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	He YJ (2006), Bennett EJ (2010), Olma MH (2009)	3
DDA1	1	DCAF5	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009)	2
UBXN7	3	BRWD1	6	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Raman M (2015)	2
UVRAG	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Yang Y (2016), Yang Y (2016)	2
DDB1	6	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Angers S (2006), Behrends C (2010), Pick E (2007), Pick E (2007), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Jin J (2006), Wan C (2015)	10
CUL4A	2	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Rao F (2014), Rao F (2014), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	13
HIST1H3A	3	CUL4A	2	affinity chromatography technology, pull down	Higa LA (2006), Higa LA (2006)	2
DCUN1D5	0	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bommelje CC (2013), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	4
CRBN	2	COPS7A	0	affinity chromatography technology	Kroenke J (2014)	1
COPS5	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Rao F (2014), Pick E (2012), Groisman R (2003), Groisman R (2003), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	19
SKP1	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Staropoli JF (2003), Kumar R (2005), Wang W (2004), Ohta T (2001), Oshikawa K (2003), Liu J (2002), Li X (2003), Zhou W (2014), Zhou W (2014), Hao J (2015), Hauri S (2016)	11
CUL4A	2	GNB2	3	affinity chromatography technology, affinity chromatography technology	Zha Z (2015), Zha Z (2015)	2
COPS5	0	MDM2	2	affinity chromatography technology, pull down	Zhang XC (2008), Zhang XC (2008)	2
DDA1	1	PWP1	3	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
DCAF4	3	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
HIST1H1C	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Kim K (2013), Kim K (2013), Kim K (2013)	3
MDM2	2	CUL4B	8	affinity chromatography technology	Latini P (2011)	1
UBXN7	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	3
RFWD2	0	DCAF11	2	affinity chromatography technology	Olma MH (2009)	1
MDM2	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Latini P (2011), Jacob AG (2014)	2
DDB1	6	DCAF12	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006)	3
DDA1	1	COPS2	5	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
GRK5	7	DDB2	1	affinity chromatography technology	Wu Z (2012)	1
CUL4B	8	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Higa LA (2006)	4
DCAF4L2	3	DDB1	6	affinity chromatography technology, affinity chromatography technology	Wang H (2016), Wang H (2016)	2
RFWD2	0	CDKN1B	1	biochemical, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Choi HH (2015), Choi HH (2015), Choi HH (2015), Choi HH (2015), Choi HH (2015)	5
DCUN1D2	0	CAND1	2	affinity chromatography technology, affinity chromatography technology, pull down	Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016)	3
CDKN1A	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, fluorescent resonance energy transfe, affinity chromatography technology, imaging technique	Zhang Z (2004), Zhang Z (2004), Zhang Z (2004), Jin Y (2003), Jin Y (2003), Wang B (2010), Xu H (2010), Xu H (2010), Frum R (2007), Chen TC (2014)	10
DTL	0	GPS1	1	affinity chromatography technology	Higa LA (2006)	1
HSP90AA1	7	CHEK1	2	affinity chromatography technology, pull down, affinity chromatography technology	Ha K (2011), Arlander SJ (2006), Taipale M (2012)	3
GRK5	7	COPS4	0	affinity chromatography technology	Wu Z (2012)	1
COPS7A	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
RASSF1	3	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
DCUN1D5	0	DDB1	6	affinity chromatography technology	Keuss MJ (2016)	1
UBC	7	GRWD1	3	affinity chromatography technology	Matsumoto M (2005)	1
COPS3	1	SKP1	0	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	CDKN1B	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Caballero OL (2002), Kouvaraki MA (2006), Kouvaraki MA (2006), Kouvaraki MA (2006), Hsieh YH (2007), Hwang CY (2004), Hwang CY (2004), Pan Y (2012), Wang Y (2008), Wang Y (2008), Yamaguchi F (2008), Wang Y (2014), Zhang H (2017), Zhang H (2017)	14
CUL5	1	DDB1	6	affinity chromatography technology	Bennett EJ (2010)	1
DDB1	6	DCAF16	0	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006)	2
TUBG1	2	SKP1	0	affinity chromatography technology	Fogeron ML (2013)	1
DCUN1D1	0	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	DCAF8	1	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017), Boldt K (2016)	7
CUL4B	8	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Jin J (2006), Hein MY (2015), Wang X (2017)	4
DET1	2	COPS3	1	affinity chromatography technology	Huttlin EL (2017)	1
ATXN3	2	HSP90AA1	7	affinity chromatography technology	Liu H (2016)	1
CCNG1	1	DDB1	6	affinity chromatography technology	Huttlin EL (2017)	1
NEDD8	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
HSP90AA1	7	ASB4	2	affinity chromatography technology	Taipale M (2012)	1
DDB1	6	GNB2	3	affinity chromatography technology, affinity chromatography technology	Zha Z (2015), Zha Z (2015)	2
UBC	7	SKP1	0	affinity chromatography technology, affinity chromatography technology	Matsumoto M (2005), Bish RA (2007)	2
DDB1	6	PCNA	0	affinity chromatography technology	Angers S (2006)	1
CUL4A	2	WDTC1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2017)	4
MDM2	2	EEF1A1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Frum R (2007), Frum R (2007), Frum R (2007), Tsai NP (2012), Tsai NP (2012)	5
COPS5	0	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Bhansali M (2014), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	13
COPS5	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Groisman R (2006)	5
TUBG1	2	EEF1A1	0	affinity chromatography technology	Fogeron ML (2013)	1
DCUN1D3	1	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
GRK5	7	COPS2	5	affinity chromatography technology	Wu Z (2012)	1
COPS5	0	DCAF12	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	CRBN	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Olma MH (2009), Kroenke J (2014)	3
PCNA	0	SENP8	0	affinity chromatography technology	Guan J (2017)	1
COPS2	5	COPS7B	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	7
DCUN1D1	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
DDB1	6	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009)	3
COPS8	2	GPS1	1	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Stotland A (2012), Sharon M (2009), Sun Y (2002), Kristensen AR (2012), Lingaraju GM (2014), Lyapina S (2001), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
COPS6	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
NF2	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology	Huang J (2008), Huang J (2008), Huang J (2008), Huang J (2008), Huang J (2008), Li W (2010), Li W (2010), Li W (2010), Mori T (2014), Mori T (2014), Mori T (2014), Zhou L (2015), Laulajainen M (2011), Laulajainen M (2011)	14
CUL5	1	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXW5	6	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu J (2008), He YJ (2006), Kanei-Ishii C (2012)	3
COPS5	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009)	3
CUL4B	8	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Hein MY (2015)	4
GPS1	1	SKP1	0	affinity chromatography technology	Lyapina S (2001)	1
COPS5	0	AMBRA1	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
UBC	7	DCAF5	1	affinity chromatography technology	Matsumoto M (2005)	1
COPS2	5	DCAF6	0	affinity chromatography technology	Huttlin EL (2015)	1
DDB1	6	TOR1AIP2	2	affinity chromatography technology	Angers S (2006)	1
HIST1H3A	3	RBBP7	1	affinity chromatography technology	Foltz DR (2009)	1
RFWD2	0	COPS2	5	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
CUL4B	8	CUL5	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010)	2
GPS1	1	RBX1	2	affinity chromatography technology	Lyapina S (2001)	1
UBXN7	3	RBX1	2	affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Bandau S (2012)	2
RFWD2	0	SKP1	0	affinity chromatography technology	Olma MH (2009)	1
DDA1	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Olma MH (2009), Olma MH (2009)	3
RBX1	2	DCUN1D3	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meyer-Schaller N (2009), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	4
PCNA	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Jascur T (2011), Jascur T (2011), Dar A (2014), Terai K (2010), Higa LA (2006), Higa LA (2006)	6
TUBG1	2	HSPA1A	0	affinity chromatography technology	Fogeron ML (2013)	1
COPS6	0	DCAF12	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
DDB2	1	DDB1	6	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bergametti F (2002), Martinez E (2001), Guerrero-Santoro J (2008), Angers S (2006), Wang H (2006), Kapetanaki MG (2006), Kapetanaki MG (2006), Higa LA (2006), Takedachi A (2010), Fischer ES (2011), Scrima A (2008), Groisman R (2003), Groisman R (2003), Schroefelbauer B (2007), Kulaksiz G (2005), Inoki T (2004), Bontron S (2002), Rapic-Otrin V (2003), Olma MH (2009), Liu W (2000), Jin J (2006), Huttlin EL (2015), Zhao R (2014), Xie X (2015), Groisman R (2006), Yang Y (2016), Huttlin EL (2017), Chitale S (2017), Fantini D (2017), Fantini D (2017), Ohtake F (2007)	31
DTL	0	MDM2	2	affinity chromatography technology	Banks D (2006)	1
DCUN1D4	0	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
DCUN1D5	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
NF2	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang J (2008), Huang J (2008), Huang J (2008), Li W (2010), Li W (2010), Zhou L (2015)	6
DET1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Angers S (2006), Jin J (2006), Pick E (2007), Pick E (2007), Pick E (2007), Jin J (2006), Huttlin EL (2017)	8
MRPS11	1	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
DCUN1D5	0	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bommelje CC (2013), Keuss MJ (2016), Keuss MJ (2016)	3
DDB1	6	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Wang H (2006), Kapetanaki MG (2006), Hu J (2004), Ahn J (2010), Fischer ES (2011), Groisman R (2006)	6
DCAF1	5	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009), Hein MY (2015)	3
DET1	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS5	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Fang L (2008), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Oh W (2006), Olma MH (2009), Havugimana PC (2012), Christmann M (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Scherer PC (2016), Huttlin EL (2017), Boldt K (2016)	15
UBC	7	TOR1AIP2	2	pull down	Zhang X (2017)	1
CCNG1	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
COPS6	0	CDKN1B	1	affinity chromatography technology	Choi HH (2015)	1
CUL4A	2	DCAF15	3	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Jin J (2006)	2
COPS7B	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
HIST1H1C	2	CUL4A	2	affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Kim K (2013), Kim K (2013), Kim K (2013), Kim K (2013)	4
CUL4A	2	DCAF4L1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	3
DCAF1	5	HIST1H3A	3	pull down, pull down	Kim K (2012), Kim K (2012)	2
DCAF11	2	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
COPS4	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Huttlin EL (2017)	2
LIG1	4	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Peng Z (2016), Peng Z (2016)	2
UBXN7	3	PHIP	20	affinity chromatography technology	Raman M (2015)	1
UVRAG	2	RBX1	2	affinity chromatography technology	Yang Y (2016)	1
MDM2	2	LATS1	3	affinity chromatography technology	Matallanas D (2011)	1
CUL4A	2	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Min KW (2005), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	10
CUL4B	8	GRWD1	3	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Higa LA (2006)	2
CUL4A	2	DCAF8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Jin J (2006), Huttlin EL (2017)	5
RFWD2	0	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	PHIP	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Jin J (2006)	4
HIST1H1A	0	RBX1	2	affinity chromatography technology	Kim K (2013)	1
COPS6	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
MDM2	2	DCAF8	1	affinity chromatography technology	Jacob AG (2014)	1
COPS3	1	DTL	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Higa LA (2006)	2
GRK5	7	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
DCUN1D1	0	COPS4	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF1	5	COPS8	2	affinity chromatography technology, affinity chromatography technology	Hrecka K (2007), Huttlin EL (2017)	2
CUL4A	2	TOR1AIP2	2	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
CUL4A	2	CDT1	2	affinity chromatography technology, affinity chromatography technology, biochemical	Hu J (2004), Higa LA (2003), He YJ (2006)	3
RBX1	2	HSPA1A	0	affinity chromatography technology	Dias DC (2002)	1
COPS3	1	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
CCNG1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ERCC8	1	UBXN7	3	affinity chromatography technology	He J (2016)	1
GPS1	1	SENP8	0	far western blotting, far western blotting	Christmann M (2013), Christmann M (2013)	2
COPS3	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, far western blotting, two hybrid, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Min KW (2005), Enchev RI (2010), Stotland A (2012), Sharon M (2009), Kapelari B (2000), Tsuge T (2001), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	12
CUL4B	8	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2017)	2
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
COPS7A	0	COPS2	5	affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Uhle S (2003), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
RFWD2	0	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
NEDD8	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
CUL4A	2	DCAF5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006)	3
CUL4B	8	DCAF10	2	affinity chromatography technology	Hein MY (2015)	1
CUL4A	2	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009)	7
DDB2	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
TRPC4AP	4	RBX1	2	affinity chromatography technology	Choi SH (2010)	1
CRBN	2	COPS2	5	affinity chromatography technology	Kroenke J (2014)	1
RFWD2	0	COPS8	2	biochemical, affinity chromatography technology	Yi C (2002), Olma MH (2009)	2
CUL4A	2	GRWD1	3	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), He YJ (2006)	2
COPS8	2	CRBN	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Kroenke J (2014)	2
DDB1	6	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006), Jin J (2006), Higa LA (2006), Rossi M (2013), Shibata E (2011), Higa LA (2006), Higa LA (2006)	8
CUL4B	8	DCUN1D1	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology	Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Kim AY (2008), Kim AY (2008), Monda JK (2013), Keuss MJ (2016)	8
COPS3	1	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	4
COPS5	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D1	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXW5	6	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hu J (2008), He YJ (2006), Kanei-Ishii C (2012)	3
HSP90AA1	7	CDKN1B	1	genetic interference	Srivas R (2016)	1
RFWD2	0	COPS3	1	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
COPS5	0	DCAF4L1	3	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chua YS (2011), Chua YS (2011), Tron AE (2012), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Liu J (2002), Huttlin EL (2017)	8
CRBN	2	DDA1	1	affinity chromatography technology	Kroenke J (2014)	1
DCUN1D1	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
DCAF8	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Huttlin EL (2017)	2
CUL4B	8	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Bennett EJ (2010), Bennett EJ (2010), Hein MY (2015)	6
DDB1	6	GPS1	1	affinity chromatography technology, pull down, fluorescent resonance energy transfe	Jin J (2006), Emberley ED (2012), Cavadini S (2016)	3
DDB1	6	TRPC4AP	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Choi SH (2010), Jamal A (2015), Huttlin EL (2017)	4
CUL4A	2	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2017)	4
DCUN1D5	0	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
DCUN1D4	0	CUL5	1	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
COPS8	2	COPS7B	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	5
CUL4B	8	DDB2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Higa LA (2006), Bennett EJ (2010), Jin J (2006), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	9
CUL4A	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Chew EH (2007), Groisman R (2006)	3
COPS6	0	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2015), Huttlin EL (2017)	4
CUL4B	8	CDT1	2	affinity chromatography technology	Higa LA (2003)	1
DCUN1D3	1	CUL4A	2	pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	4
RASSF1	3	SKP1	0	affinity chromatography technology	Song MS (2008)	1
ERCC8	1	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Olma MH (2009)	3
RASSF1	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Jiang L (2011), Jiang L (2011)	2
DCUN1D3	1	CUL4B	8	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
ERCC8	1	COPS2	5	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
ATXN3	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Tu Y (2017), Tu Y (2017)	2
COPS8	2	DCAF11	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
DCUN1D1	0	CUL5	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	9
DCUN1D1	0	COPS5	0	affinity chromatography technology	Bennett EJ (2010)	1
DCAF4	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Hein MY (2015), Huttlin EL (2017)	3
DCUN1D5	0	CUL4B	8	pull down, enzymatic study, affinity chromatography technology	Monda JK (2013), Monda JK (2013), Keuss MJ (2016)	3
DDB2	1	HIST1H3A	3	affinity chromatography technology, affinity chromatography technology	Fantini D (2017), Fantini D (2017)	2
CUL4A	2	DCAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Jin J (2006), Chen HH (2017)	5
COPS6	0	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Olma MH (2009)	5
DCAF4L2	3	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Wang H (2016)	3
ASB4	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Andresen CA (2014), Andresen CA (2014)	2
DDA1	1	DCAF16	0	affinity chromatography technology	Olma MH (2009)	1
COPS6	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Enchev RI (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	11
TRPC4AP	4	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
COPS5	0	SKP1	0	affinity chromatography technology	Bennett EJ (2010)	1
DDA1	1	CAND1	2	affinity chromatography technology	Behrends C (2010)	1
CUL5	1	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Zhang X (2017)	2
CUL4A	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Bennett EJ (2010), Taipale M (2012)	3
DDB1	6	COPS8	2	affinity chromatography technology, pull down	Angers S (2006), Emberley ED (2012)	2
DCUN1D3	1	RNF7	0	affinity chromatography technology	Keuss MJ (2016)	1
CUL5	1	COPS2	5	affinity chromatography technology	Bennett EJ (2010)	1
GRK5	7	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012)	2
CDKN1A	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Gao J (2015)	3
PCNA	0	EEF1A1	0	affinity chromatography technology	Naryzhny SN (2010)	1
DCUN1D1	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
ATXN3	2	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Kristensen LV (2018), Kristensen LV (2018)	2
DDB1	6	COPS4	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Angers S (2006), Jin J (2006), Emberley ED (2012), Olma MH (2009)	4
COPS5	0	MRPS11	1	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	TRPC4AP	4	affinity chromatography technology	Bennett EJ (2010)	1
COPS3	1	CRBN	2	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Kroenke J (2014)	2
COPS6	0	DCAF10	2	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	CRBN	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Kroenke J (2014)	2
CRBN	2	HSP90AA1	7	affinity chromatography technology	Nguyen TV (2016)	1
CUL4A	2	UBC	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Bennett EJ (2010), Olma MH (2009), Wu K (2016)	4
COPS3	1	DCAF4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL4B	8	TOR1AIP2	2	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1B	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miranda-Carboni GA (2008), Bondar T (2006), Li B (2006), Li B (2006), Gao J (2015)	5
AMBRA1	7	COPS8	2	affinity chromatography technology	Antonioli M (2014)	1
CUL4B	8	PCNA	0	affinity chromatography technology	Banks D (2006)	1
GRK5	7	EEF1A1	0	affinity chromatography technology	Wu Z (2012)	1
CUL5	1	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
COPS8	2	COPS5	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Fang L (2008), Bennett EJ (2010), Olma MH (2009), Asare Y (2013), Huttlin EL (2015), Huttlin EL (2017), Boldt K (2016)	9
CUL4B	8	COPS4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Hein MY (2015), Yang Y (2015)	4
COPS5	0	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	COPS7A	0	biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015), Hein MY (2015), Huang X (2016)	6
CDKN1A	1	CDKN1B	1	genetic interference, imaging technique	Hsu SP (2008), Chen TC (2014)	2
DDB1	6	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009), He F (2013)	6
DET1	2	COPS7B	0	affinity chromatography technology	Huttlin EL (2017)	1
DDB2	1	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Olma MH (2009), Hein MY (2015)	6
DCUN1D2	0	CUL4A	2	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016), Keuss MJ (2016)	5
DDB1	6	CRBN	2	affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology	Angers S (2006), Ito T (2010), Chamberlain PP (2014), Liu Y (2015), Diaz-Rodriguez E (2016), Xu Q (2016), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Eichner R (2016), Matyskiela ME (2018), Kroenke J (2014)	12
AMBRA1	7	UBC	7	affinity chromatography technology	Antonioli M (2014)	1
LRWD1	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Shen Z (2012), Shen Z (2012)	2
CUL4B	8	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Olma MH (2009)	2
COPS3	1	TOR1AIP2	2	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Nathan JA (2013)	2
CUL4A	2	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2017)	6
CDKN1A	1	PCNA	0	two hybrid, pull down, pull down, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Frouin I (2003), Watanabe H (1998), Fotedar R (1996), Jonsson ZO (1998), Gulbis JM (1996), Touitou R (2001), Yu P (2001), Yu P (2001), Chen X (2007), Chen X (2007), Wang SC (2006), Carujo S (2006), Garcia-Wilson E (2005), Howlett NG (2009), Jin Y (2008), Lee JY (2009), Ando T (2001), Ando T (2001), Takasaki Y (2001), Logette E (2011), Mistafa O (2010), Mistafa O (2010), Bruning JB (2004), Punchihewa C (2012), Mattock H (2001), Waga S (1994), Waga S (1994), Poon RY (1996), Zhang Y (1999), Warbrick E (1995), Warbrick E (1995), Poon RY (1998), Poon RY (1998), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Rizzardi LF (2014), Trombetta A (2013), Trombetta A (2013), Kim DH (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Coleman KE (2015), Huttlin EL (2017), Roessig L (2001), Roessig L (2001)	48
DTL	0	CDT1	2	enzymatic study, pull down, pull down	Hayashi A (2014), Chandrasekaran S (2011), Coleman KE (2015)	3
AMBRA1	7	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Jin J (2006), Antonioli M (2014), Antonioli M (2014), Antonioli M (2014)	4
DCAF4L2	3	COPS5	0	affinity chromatography technology	Wang H (2016)	1
CAND1	2	GRWD1	3	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1A	1	ATXN3	2	two hybrid	Vinayagam A (2011)	1
COPS5	0	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Fang L (2008), Enchev RI (2010), Bennett EJ (2010), Oh W (2006), Olma MH (2009), Olma MH (2009), Asare Y (2013), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017)	13
COPS6	0	COPS7A	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sharon M (2009), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	15
DCUN1D2	0	CUL4B	8	pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Monda JK (2013), Meyer-Schaller N (2009), Monda JK (2013), Keuss MJ (2016)	4
CHEK1	2	CDKN1A	1	affinity chromatography technology	Tian H (2002)	1
CUL4B	8	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017), Higa LA (2006)	5
DCAF4L2	3	COPS7B	0	affinity chromatography technology	Wang H (2016)	1
DDB2	1	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Hein MY (2015)	4
COPS6	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), McCall CM (2008), Bennett EJ (2010), Olma MH (2009)	4
NEDD8	0	DCAF11	2	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Olma MH (2009), Olma MH (2009), Choi HH (2011), Choi HH (2011)	4
SENP8	0	NEDD8	0	pull down, x-ray crystallography, enzymatic study, x-ray crystallography, enzymatic study	Wu K (2003), Shen LN (2005), Engels IH (2009), Reverter D (2005), Shen LN (2005)	5
DCUN1D1	0	UBC	7	affinity chromatography technology, pull down, affinity chromatography technology	Bennett EJ (2010), Huang G (2014), Huang G (2014)	3
DCUN1D4	0	RBX1	2	affinity chromatography technology	Keuss MJ (2016)	1
DCAF4L2	3	COPS8	2	affinity chromatography technology	Wang H (2016)	1
DDA1	1	ERCC8	1	affinity chromatography technology	Olma MH (2009)	1
COPS5	0	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Huttlin EL (2017)	3
ERCC8	1	PCNA	0	affinity chromatography technology	Fei J (2012)	1
COPS8	2	COPS6	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	10
UBXN7	3	DDB1	6	affinity chromatography technology	Alexandru G (2008)	1
DCUN1D2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Keuss MJ (2016), Keuss MJ (2016)	2
HIST1H1A	0	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCUN1D1	0	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Keuss MJ (2016)	2
CUL4B	8	RBBP7	1	affinity chromatography technology	Mouysset J (2015)	1
SLBP	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Dankert JF (2016), Dankert JF (2016)	2
GPS1	1	COPS7B	0	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Stotland A (2012), Havugimana PC (2012), Huang X (2016), Huttlin EL (2017)	4
GLMN	2	DTL	0	affinity chromatography technology	Huttlin EL (2017)	1
SKP1	0	CDKN1A	1	imaging technique	Chen TC (2014)	1
DDB1	6	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology	Jin J (2006), Groisman R (2003), Groisman R (2003), Meulenbroek EM (2012), Fei J (2012), Jin J (2006), He J (2016), Groisman R (2006), Chitale S (2017), Ohtake F (2007)	10
DCUN1D1	0	NEDD8	0	affinity chromatography technology	Bennett EJ (2010)	1
RFWD2	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Higa LA (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Lu G (2014)	7
COPS4	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
AMBRA1	7	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Olma MH (2009), Antonioli M (2014)	4
ERCC8	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
COPS5	0	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Neuss H (2007), Fang L (2008), Orel L (2010), Uhle S (2003), Bennett EJ (2010), Luke-Glaser S (2007), Kapelari B (2000), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	17
CUL4A	2	SENP8	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Gastaldello S (2010), Gastaldello S (2010), Gastaldello S (2010)	3
DTL	0	RBX1	2	affinity chromatography technology	Shibata E (2011)	1
DDB1	6	DCAF6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Chen HH (2017), Chen HH (2017), Chen HH (2017)	6
CDKN1B	1	DDB1	6	affinity chromatography technology	Iovine B (2011)	1
DCAF1	5	COPS3	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Hrecka K (2007), Olma MH (2009)	3
CDKN1A	1	COPS6	0	two hybrid	Vinayagam A (2011)	1
COPS6	0	DCAF4L1	3	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D3	1	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Huang G (2014), Keuss MJ (2016), Keuss MJ (2016), Keuss MJ (2016), Zhang S (2016), Zhang S (2016)	6
ATXN3	2	NEDD8	0	two hybrid, two hybrid, pull down	Ferro A (2007), Ferro A (2007), Ferro A (2007)	3
DDA1	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Hein MY (2015)	2
CUL4A	2	DCAF10	2	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
DCAF6	0	CUL4B	8	affinity chromatography technology	Jin J (2006)	1
RBX1	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Norman JA (2006)	2
COPS6	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	12
DCAF4L2	3	COPS3	1	affinity chromatography technology	Wang H (2016)	1
MDM2	2	HSP90AA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, biochemical, unspecified method, affinity chromatography technology	Lu TL (2010), Burch L (2004), Burch L (2004), Burch L (2004), Burch L (2004), Burch LR (2004), Okoro DR (2013)	7
COPS6	0	CUL5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009)	5
COPS6	0	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	5
COPS6	0	GPS1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Stotland A (2012), Sharon M (2009), Bennett EJ (2010), Lingaraju GM (2014), Huttlin EL (2015), Huttlin EL (2017)	7
COPS6	0	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS8	2	DTL	0	affinity chromatography technology	Huttlin EL (2017)	1
CRBN	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ito T (2010), Xu G (2013), Nguyen TV (2016), Nguyen TV (2016), Kroenke J (2014)	5
CHEK1	2	DTL	0	affinity chromatography technology, enzymatic study, enzymatic study	Huh J (2013), Cheng YC (2013), Huh J (2013)	3
DDA1	1	DTL	0	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
TRPC4AP	4	DDA1	1	affinity chromatography technology, affinity chromatography technology	Choi SH (2010), Huttlin EL (2017)	2
CDKN1A	1	HSPA1A	0	affinity chromatography technology	Fogeron ML (2013)	1
ASB4	2	DDB1	6	affinity chromatography technology	Andresen CA (2014)	1
NEDD8	0	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
COPS7B	0	COPS7A	0	biochemical, affinity chromatography technology	Kristensen AR (2012), Huttlin EL (2017)	2
DDA1	1	COPS4	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
LRWD1	1	TUBG1	2	affinity chromatography technology	Hein MY (2015)	1
DDA1	1	DDB2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Hein MY (2015)	2
HIST1H1C	2	DCAF1	5	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
COPS5	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	RBBP7	1	affinity chromatography technology, affinity chromatography technology	He YJ (2006), Mouysset J (2015)	2
CUL4B	8	ERCC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Fei J (2012), Hein MY (2015)	3
COPS5	0	COPS6	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Fang L (2008), Sharon M (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Choi HH (2011), Kristensen AR (2012), Birol M (2014), Birol M (2014), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	18
COPS5	0	DCAF8	1	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
HIST1H1A	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Kim K (2013), Kim K (2013)	2
DCAF4	3	GPS1	1	affinity chromatography technology	Huttlin EL (2017)	1
DDB1	6	DCAF15	3	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006)	2
CUL4A	2	DCAF11	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), He YJ (2006), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Olma MH (2009), Jin J (2006), Huttlin EL (2017), Lo JY (2017)	10
GLMN	2	CRBN	2	affinity chromatography technology	Huttlin EL (2017)	1
GPS1	1	NF2	1	affinity chromatography technology	Stotland A (2012)	1
COPS2	5	HIST1H3A	3	pull down	Eckey M (2007)	1
RFWD2	0	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Jin J (2006), He YJ (2006), Olma MH (2009), Lu G (2014), Lu G (2014)	6
DCAF4	3	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Guerrero-Santoro J (2008), Angers S (2006), Bennett EJ (2010), Bennett EJ (2010), Sertic S (2013)	5
DCAF1	5	COPS7B	0	affinity chromatography technology	McCall CM (2008)	1
UVRAG	2	DDB2	1	affinity chromatography technology	Yang Y (2016)	1
NF2	1	LATS1	3	pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Li Y (2015), Li Y (2015), Li Y (2015), Li Y (2015), Yin F (2013), Yin F (2013), Yin F (2013), Yin F (2013)	8
RFWD2	0	COPS5	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Olma MH (2009)	2
DDB2	1	ERCC8	1	affinity chromatography technology	Groisman R (2003)	1
CUL5	1	DCAF11	2	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	PWP1	3	affinity chromatography technology	Bennett EJ (2010)	1
DCAF8	1	DDB1	6	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Olma MH (2009), Klein CJ (2014), Jin J (2006), Huttlin EL (2017)	6
COPS4	0	COPS7A	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Sharon M (2009), Luke-Glaser S (2007), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Huang X (2016)	13
CRBN	2	GPS1	1	affinity chromatography technology	Kroenke J (2014)	1
GPS1	1	COPS4	0	affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical	Stotland A (2012), Tsuge T (2001), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Lingaraju GM (2014), Wan C (2015)	7
CDKN1B	1	HIST1H1A	0	enzymatic study	Ciarallo S (2002)	1
COPS6	0	COPS7B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huang X (2016), Huttlin EL (2017), Boldt K (2016)	9
DCAF4L2	3	COPS4	0	affinity chromatography technology	Wang H (2016)	1
CUL5	1	COMMD1	1	pull down, pull down	Mao X (2011), Mao X (2011)	2
CHEK1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Leung-Pineda V (2009), Huh J (2013), Williamson EA (2014)	4
CUL4A	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Lo YH (2012), Banks D (2006)	3
COPS7A	0	DCAF10	2	affinity chromatography technology	Hein MY (2015)	1
NEDD8	0	DCAF1	5	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1B	1	SKP1	0	unspecified method, unspecified method	Carrano AC (1999), Ooi LC (2013)	2
DDA1	1	DCAF1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical	Behrends C (2010), Hrecka K (2007), Hrecka K (2007), Olma MH (2009), Olma MH (2009), Wan C (2015)	6
DCUN1D1	0	DCUN1D2	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	TUBG1	2	affinity chromatography technology	Thirunavukarasou A (2015)	1
CUL4A	2	EEF1A1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Morrissey C (2015)	2
DET1	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Angers S (2006), Jin J (2006), Pick E (2007), Huttlin EL (2017)	5
ATXN3	2	UBC	7	pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, x-ray crystallography, pull down, imaging technique, enzymatic study, pull down	Winborn BJ (2008), Mao Y (2005), Berke SJ (2005), Matsumoto M (2005), Bremm A (2010), Nicastro G (2010), Nicastro G (2010), Donaldson KM (2003), Chai Y (2004), Chai Y (2004), Nathan JA (2013), Seki T (2013), Yang H (2014), Yang H (2014), Blount JR (2014), Evers MM (2013), Weeks SD (2011), Donaldson KM (2003), Winborn BJ (2008), Faggiano S (2015), Wauer T (2015), Satoh T (2014), Satoh T (2014), Zhang X (2017), Toonen LJA (2017), Toonen LJA (2017), Kwasna D (2018)	27
DET1	2	COPS2	5	affinity chromatography technology	Huttlin EL (2017)	1
CUL5	1	COPS3	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
CUL4A	2	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Olma MH (2009), Olma MH (2009), Hein MY (2015)	7
CUL4A	2	TUBG1	2	affinity chromatography technology, enzymatic study	Thirunavukarasou A (2015), Thirunavukarasou A (2015)	2
DDA1	1	DCAF6	0	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	GPS1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Hein MY (2015), Higa LA (2006)	3
UBC	7	UBXN7	3	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Kelsall IR (2013), Alexandru G (2008), Besten Wd (2012), Besten Wd (2012)	4
CHEK1	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Liu S (2009), Huh J (2013), Zhang YW (2005)	4
DDA1	1	DCAF12	0	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	GPS1	1	affinity chromatography technology	Bennett EJ (2010)	1
EEF1A1	0	RBX1	2	affinity chromatography technology	Morrissey C (2015)	1
CUL4A	2	DLC1	11	affinity chromatography technology, affinity chromatography technology	Kim TY (2013), Kim TY (2013)	2
DDB2	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
MDM2	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Wang L (2011), Wang L (2011)	2
DCAF4L2	3	COPS6	0	affinity chromatography technology	Wang H (2016)	1
CUL4A	2	HSPA1A	0	affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Bennett EJ (2010)	2
CUL4A	2	LATS1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ni W (2017), Ni W (2017), Deng J (2016)	3
DDB1	6	DCAF4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Jin J (2006), Jin J (2006), Huttlin EL (2017)	4
DET1	2	COPS7A	0	affinity chromatography technology	Huttlin EL (2017)	1
RFWD2	0	DCAF1	5	affinity chromatography technology	Olma MH (2009)	1
HSP90AA1	7	FBXW5	6	affinity chromatography technology	Taipale M (2012)	1
COPS6	0	PWP1	3	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	RBX1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Kim AY (2008), Zheng J (2002), Zheng J (2002), Liu J (2002), Liu J (2002)	7
CAND1	2	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL5	1	RBX1	2	x-ray crystallography, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Duda DM (2008), Ohta T (1999), Furukawa M (2002), Tron AE (2012), Tron AE (2012), Yu Y (2004), Huang DT (2009), Wang X (2015), Wang X (2015), Wang X (2015)	10
COPS5	0	DDB2	1	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), He YJ (2006), Groisman R (2003), Groisman R (2003), Bennett EJ (2010), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
NEDD8	0	SKP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Hauri S (2016)	3
NEDD8	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
CUL5	1	DDB2	1	affinity chromatography technology	Bennett EJ (2010)	1
DCUN1D4	0	CUL4A	2	pull down, enzymatic study	Monda JK (2013), Monda JK (2013)	2
RNF7	0	CUL4A	2	two hybrid, enzymatic study	Ohta T (1999), Huang DT (2009)	2
DDA1	1	COPS8	2	affinity chromatography technology	Olma MH (2009)	1
CUL5	1	EEF1A1	0	affinity chromatography technology	Bennett EJ (2010)	1
HSP90AA1	7	HSPA1A	0	pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kanelakis KC (2002), Gano JJ (2010), Falsone SF (2005), Brychzy A (2003), Scholz GM (2001), Scholz GM (2001)	6
AMBRA1	7	GPS1	1	affinity chromatography technology	Antonioli M (2014)	1
DET1	2	DDA1	1	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pick E (2007), Pick E (2007), Pick E (2007), Olma MH (2009), Pick E (2007), Huttlin EL (2017)	6
COPS5	0	CHEK1	2	affinity chromatography technology	Bennett EJ (2010)	1
COPS7A	0	DTL	0	affinity chromatography technology	Hein MY (2015)	1
LRWD1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Shen Z (2012), Shen Z (2012)	2
DDA1	1	TOR1AIP2	2	affinity chromatography technology	Olma MH (2009)	1
CUL4B	8	COMMD1	1	pull down, pull down	Mao X (2011), Mao X (2011)	2
CUL5	1	COPS7A	0	affinity chromatography technology	Bennett EJ (2010)	1
GPS1	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Stotland A (2012), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Scherer PC (2016)	5
DDB2	1	COPS8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
DDB2	1	COPS7B	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DET1	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology	Jin J (2006), Huttlin EL (2017)	2
CDKN1A	1	DTL	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Kim DH (2010), Zhang L (2012), Abbas T (2008), Shibata E (2011)	7
DCAF1	5	COPS4	0	affinity chromatography technology, affinity chromatography technology	McCall CM (2008), Olma MH (2009)	2
RBX1	2	GLMN	2	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, pull down	Tron AE (2012), Tron AE (2012), Duda DM (2012), Duda DM (2012), Tron AE (2012), Tron AE (2012)	6
DDB1	6	GRWD1	3	affinity chromatography technology	He YJ (2006)	1
DDB1	6	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Norman JA (2006), Bennett EJ (2010)	3
MRPS11	1	DCAF5	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL5	1	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
DDA1	1	RFWD2	0	affinity chromatography technology, affinity chromatography technology	Olma MH (2009), Lu G (2014)	2
DDB1	6	AMBRA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Behrends C (2010), Jin J (2006), Antonioli M (2014), Antonioli M (2014)	5
COPS5	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Olma MH (2009), He F (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	9
RNF7	0	CUL4B	8	enzymatic study	Huang DT (2009)	1
DET1	2	COPS4	0	affinity chromatography technology	Huttlin EL (2017)	1
COPS6	0	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huang X (2005), Bennett EJ (2010), Kapelari B (2000), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	11
CAND1	2	HSPA1A	0	affinity chromatography technology	Bennett EJ (2010)	1
CUL4B	8	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CDKN1A	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Fogeron ML (2013)	4
COPS3	1	COPS7A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2005), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Kristensen AR (2012), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Huang X (2016), Huttlin EL (2017)	10
RASSF1	3	TUBG1	2	pull down	Liu L (2003)	1
DCUN1D1	0	LATS1	3	affinity chromatography technology	Bennett EJ (2010)	1
ERCC8	1	COPS8	2	affinity chromatography technology, affinity chromatography technology, biochemical	Groisman R (2003), Groisman R (2003), Groisman R (2006)	3
ASB4	2	RNF7	0	affinity chromatography technology	Andresen CA (2014)	1
DCUN1D4	0	CAND1	2	affinity chromatography technology, pull down	Keuss MJ (2016), Keuss MJ (2016)	2
DDA1	1	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
NEDD8	0	HIST1H1C	2	affinity chromatography technology	Bennett EJ (2010)	1
CUL4A	2	DCAF12	0	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
GRK5	7	SKP1	0	affinity chromatography technology	Wu Z (2012)	1
COPS5	0	DDA1	1	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
RASSF1	3	DDB1	6	affinity chromatography technology, affinity chromatography technology, pull down	Jiang L (2011), Jiang L (2011), Jiang L (2011)	3
COPS6	0	DDA1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Bennett EJ (2010), Olma MH (2009), Olma MH (2009)	4
CDT1	2	DDB2	1	affinity chromatography technology	Hu J (2004)	1
COPS2	5	SENP8	0	affinity chromatography technology, far western blotting	Christmann M (2013), Christmann M (2013)	2
GRK5	7	RBX1	2	affinity chromatography technology	Wu Z (2012)	1
GLMN	2	DCAF4	3	affinity chromatography technology	Huttlin EL (2017)	1
DCAF4L2	3	HIST1H1C	2	affinity chromatography technology	Wang H (2016)	1
RBX1	2	CUL4A	2	affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, biochemical, enzymatic study, pull down, biochemical	Dias DC (2002), Ohta T (1999), Guerrero-Santoro J (2008), Hu J (2004), Furukawa M (2002), Maddika S (2009), Tron AE (2012), Tron AE (2012), He YJ (2006), Gastaldello S (2012), Olma MH (2009), Kristensen AR (2012), Huang DT (2009), Pick E (2007), Yang Y (2016), Scherer PC (2016), Nguyen TV (2016)	17
UBXN7	3	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down	Bandau S (2012), Besten Wd (2012), Kelsall IR (2013)	3
DDB2	1	COPS2	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003), Kulaksiz G (2005), Olma MH (2009), Huttlin EL (2015), Huttlin EL (2017)	6
RBX1	2	CDKN1B	1	enzymatic study	Duda DM (2008)	1
PCNA	0	MDM2	2	affinity chromatography technology, affinity chromatography technology	Groehler AL (2010), Banks D (2006)	2
ERCC8	1	RBX1	2	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Groisman R (2003), Groisman R (2003), Groisman R (2006), Groisman R (2006)	4
DCAF1	5	UBC	7	affinity chromatography technology	Li W (2010)	1
CCNG1	1	MDM2	2	pull down, affinity chromatography technology	Zhao L (2003), Zhao L (2003)	2
GRK5	7	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu Z (2012), Wu Z (2012), Wu Z (2012)	3
DCAF8	1	COPS4	0	biochemical	Kristensen AR (2012)	1
DCUN1D1	0	RBX1	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim AY (2008), Kim AY (2008), Kim AY (2008), Bommelje CC (2013), Meyer-Schaller N (2009), Huang G (2014), Huang G (2014), Keuss MJ (2016), Keuss MJ (2016)	9
COPS6	0	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
DDA1	1	WDTC1	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Olma MH (2009)	2
CUL5	1	COPS8	2	affinity chromatography technology	Bennett EJ (2010)	1
DDB1	6	PWP1	3	affinity chromatography technology	He YJ (2006)	1
HSP90AA1	7	CDKN1A	1	affinity chromatography technology	Jascur T (2005)	1
CUL4A	2	BRWD1	6	affinity chromatography technology, affinity chromatography technology	Angers S (2006), Bennett EJ (2010)	2
TUBG1	2	HSP90AA1	7	biochemical, affinity chromatography technology, affinity chromatography technology	Wigley WC (1999), Fogeron ML (2013), Hein MY (2015)	3
DCAF11	2	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Hein MY (2015), Huttlin EL (2017)	3
GLMN	2	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
RNF7	0	CUL5	1	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, enzymatic study, pull down, biochemical, two hybrid, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ohta T (1999), Bennett EJ (2010), Tan M (2008), Kelsall IR (2013), Kelsall IR (2013), Zhou W (2014), Rolland T (2014), Huang DT (2009), Kim DY (2013), Kim DY (2013), Yu H (2011), Bulatov E (2015), Wang X (2015), Wang X (2015), Wang X (2015), Kershaw NJ (2014), Huttlin EL (2017), Kuang P (2016), Kuang P (2016), Zhou W (2017), Zhou W (2017)	21
GLMN	2	SKP1	0	pull down	Tron AE (2012)	1
DDB1	6	DCAF1	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Jin J (2006), Jin J (2006), Ahn J (2010), Maddika S (2009), Maddika S (2009), McCall CM (2008), McCall CM (2008), Hrecka K (2007), Hrecka K (2007), Le Rouzic E (2007), Le Rouzic E (2007), Olma MH (2009), Pham TN (2011), Gerard FC (2014), Nakagawa T (2015), Wan C (2015), Kyei GB (2015), Cassiday PA (2015), Gao J (2015), Gao J (2015), Wu Y (2016), Wu Y (2016), Wang H (2017), Zhou X (2016), Zhou X (2016), Wang X (2017)	26
HIST1H3A	3	HIST1H1C	2	imaging technique	Soldi M (2013)	1
COPS4	0	SKP1	0	affinity chromatography technology	Olma MH (2009)	1
CUL4A	2	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Angers S (2006), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009)	7
DET1	2	RBX1	2	affinity chromatography technology	Wertz IE (2004)	1
COPS5	0	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
COPS6	0	DCAF16	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009)	2
NEDD8	0	PWP1	3	affinity chromatography technology	Bennett EJ (2010)	1
COPS5	0	NEDD8	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sowa ME (2009), Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Birol M (2014)	5
CUL4A	2	SKP1	0	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
DCAF4L1	3	CUL4B	8	affinity chromatography technology	Huttlin EL (2017)	1
DDB1	6	CAND1	2	affinity chromatography technology	Hu J (2004)	1
COPS5	0	RBX1	2	affinity chromatography technology	Olma MH (2009)	1
COPS8	2	COPS4	0	biochemical, affinity chromatography technology, biochemical, biochemical, pull down, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Wei N (1998), Olma MH (2009), Havugimana PC (2012), Kotiguda GG (2012), Kotiguda GG (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	9
DCAF8	1	DCAF11	2	biochemical	Kristensen AR (2012)	1
DCAF4L2	3	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Wang H (2016)	3
MDM2	2	RASSF1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Song MS (2008), Zhang H (2013), Zhang H (2013)	3
RFWD2	0	RBX1	2	affinity chromatography technology, affinity chromatography technology	Wertz IE (2004), Olma MH (2009)	2
DDA1	1	COPS7B	0	affinity chromatography technology	Olma MH (2009)	1
HIST1H3A	3	PHIP	20	bioid	Lambert JP (2015)	1
AMBRA1	7	HSP90AA1	7	affinity chromatography technology	Antonioli M (2014)	1
CUL4A	2	NF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huang J (2008), Huang J (2008), Li W (2010)	3
ERCC8	1	GPS1	1	affinity chromatography technology, affinity chromatography technology	Groisman R (2003), Groisman R (2003)	2
CUL4A	2	AMBRA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Bennett EJ (2010), Olma MH (2009), Jin J (2006), Antonioli M (2014), Antonioli M (2014), Antonioli M (2014)	6