PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
MAD1L1	2	NINL	1	two hybrid	Rual JF (2005)	1
NINL	1	CDC20	1	affinity chromatography technology, affinity chromatography technology	Wang Y (2007), Wang Y (2007)	2
MAD1L1	2	NUDC	1	biochemical	Wan C (2015)	1
HNRNPL	3	SCARA3	2	affinity chromatography technology	Fei T (2017)	1
ALOX5	1	MAD1L1	2	two hybrid	Rolland T (2014)	1
PSMA1	1	MAD1L1	2	two hybrid	Rolland T (2014)	1
NTRK1	1	TPM3	0	affinity chromatography technology	Emdal KB (2015)	1
MAD1L1	2	NEBL	4	two hybrid	Rolland T (2014)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
MAD1L1	2	FAM131C	0	two hybrid	Rual JF (2005)	1
MAD2L1	0	TRIP13	0	affinity chromatography technology, pull down, affinity chromatography technology	Wang K (2014), Miniowitz-Shemtov S (2015), Sedgwick GG (2016)	3
CDC20	1	HDAC2	1	biochemical, affinity chromatography technology	Yoon YM (2004), Yoon YM (2004)	2
TPM3	0	CCHCR1	2	two hybrid	Rolland T (2014)	1
NTRK1	1	MFAP1	3	affinity chromatography technology	Emdal KB (2015)	1
MFAP1	3	AMOTL2	5	two hybrid	Rolland T (2014)	1
SIN3A	13	MNT	2	two hybrid, pull down	Meroni G (1997), Meroni G (1997)	2
CDC5L	2	MAD1L1	2	affinity chromatography technology	Lleres D (2010)	1
AMOTL2	5	CCHCR1	2	two hybrid	Rolland T (2014)	1
SNW1	0	NONO	3	affinity chromatography technology	Lleres D (2010)	1
CDC20	1	CDC27	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kramer ER (1998), Kallio M (1998), Kallio M (1998), Nilsson J (2008), Jeganathan KB (2006), Nath S (2011), Lee YJ (2008), Lara-Gonzalez P (2011), Mansfeld J (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Lee YJ (2008), DAngiolella V (2003), Lee SJ (2012), Fang G (1998), Fang G (1998), Wolthuis R (2008), Ban KH (2007), Ge S (2009), Tipton AR (2011), Westhorpe FG (2011), Uzunova K (2012), Kwan PS (2013), Sedgwick GG (2012), Eytan E (2013), Hyun SY (2013), Lim HJ (2013), Choi BH (2014), Fogeron ML (2013), Sackton KL (2014), Shoji S (2014), Han JS (2014), Lara-Gonzalez P (2011), Hein JB (2014), Vodermaier HC (2003), Yen AH (2010), Voets E (2015), Boekhout M (2015), Kelly A (2014), Kelly A (2014), Craney A (2016), Craney A (2016), Craney A (2016), Listovsky T (2013), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Qiao R (2016), Hein JB (2016)	54
HAUS1	0	ASB7	1	affinity chromatography technology	Huttlin EL (2017)	1
TRIP13	0	CDC20	1	pull down, pull down	Miniowitz-Shemtov S (2015), Miniowitz-Shemtov S (2015)	2
MAD1L1	2	HDAC1	4	affinity chromatography technology, biochemical	Yoon YM (2004), Yoon YM (2004)	2
ZW10	2	MAD1L1	2	imaging technique	Kops GJ (2005)	1
UBC	7	VPS28	2	affinity chromatography technology, pull down	Bishop N (2002), Zhang X (2017)	2
NINL	1	CDC27	2	affinity chromatography technology	Wang Y (2007)	1
HNRNPL	3	FLNB	11	affinity chromatography technology	Fei T (2017)	1
MAD1L1	2	TEX11	0	two hybrid	Rual JF (2005)	1
SNW1	0	NUDC	1	affinity chromatography technology	Lleres D (2010)	1
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
HDAC1	4	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2003), Yao YL (2003), Yao YL (2003), Fleischer TC (2003), Fleischer TC (2003), Yang L (2003), Grozinger CM (1999), Zhang J (2002), Zhang J (2002), You A (2001), Zhang Y (1999), Zhang Y (2002), Tong JK (1998), Hassig CA (1998), Yasui D (2002), Huang EY (2000), Huang EY (2000), Kuzmichev A (2002), Kuzmichev A (2002), Martinowich K (2003), Martinowich K (2003), Suzuki M (2003), Suzuki M (2006), Nakamura T (2002), Wei Q (2005), Pflum MK (2001), Pflum MK (2001), Skowyra D (2001), Skowyra D (2001), Humphrey GW (2001), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Sun JM (2007), Karwowska-Desaulniers P (2007), Terhune SS (2010), Xue Y (1998), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Oh YM (2009), Wan C (2015), Hein MY (2015), Hsu DS (2014), Huttlin EL (2017)	45
VPS28	2	MAD1L1	2	affinity chromatography technology	Huttlin EL (2015)	1
CCDC94	0	CDC5L	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NTRK1	1	HNRNPL	3	affinity chromatography technology	Emdal KB (2015)	1
METTL21C	0	UBC	7	affinity chromatography technology	Cloutier P (2013)	1
NONO	3	HDAC2	1	affinity chromatography technology	Zhang C (2008)	1
CDC5L	2	NUDC	1	affinity chromatography technology	Lleres D (2010)	1
HDAC1	4	HDAC2	1	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology	Hakimi MA (2002), Yao YL (2003), Yao YL (2003), Hakimi MA (2003), Fischle W (2002), Johnson CA (2002), Fischle W (2001), Fischer DD (2002), Fischer DD (2002), Ashburner BP (2001), Zhang Y (1999), Tong JK (1998), Tong JK (1998), Hassig CA (1998), Hassig CA (1998), Zhang Y (1997), van der Vlag J (1999), van der Vlag J (1999), Noh EJ (2009), Noh EJ (2009), Galasinski SC (2002), Galasinski SC (2002), Galasinski SC (2002), He S (2005), Humphrey GW (2001), Park JH (2004), Park JH (2004), Sekhavat A (2007), Zhang Y (1998), Zhang Y (1998), Adenuga D (2010), Xue Y (1998), Xue Y (1998), Martinez FP (2012), Martinez FP (2012), Cui S (2011), Havugimana PC (2012), Bantscheff M (2011), Bantscheff M (2011), Joshi P (2013), Joshi P (2013), Schnur N (2007), Schnur N (2007), Oh YM (2009), Wan C (2015), Hein MY (2015), Chen TC (2014), Huttlin EL (2017)	48
NONO	3	SIN3A	13	affinity chromatography technology	Liu L (2011)	1
UBC	7	HNRNPL	3	affinity chromatography technology	Matsumoto M (2005)	1
CLEC11A	0	MAD1L1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CDC27	2	MAD1L1	2	affinity chromatography technology	Westhorpe FG (2011)	1
UBC	7	PSMA1	1	affinity chromatography technology	Matsumoto M (2005)	1
SNW1	0	MFAP1	3	two hybrid, two hybrid	Hegele A (2012), Hegele A (2012)	2
NONO	3	MAD1L1	2	two hybrid	Rual JF (2005)	1
TSC22D3	1	HDAC2	1	affinity chromatography technology	Bruscoli S (2010)	1
HNRNPL	3	TRIP13	0	affinity chromatography technology	Fei T (2017)	1
FLNB	11	MAD1L1	2	biochemical	Kristensen AR (2012)	1
CDC5L	2	SENP3	1	affinity chromatography technology, affinity chromatography technology	Lleres D (2010), Wang M (2016)	2
TPR	5	MAD1L1	2	pull down	Rodriguez-Bravo V (2014)	1
BAG5	0	MAD2L1	0	affinity chromatography technology, affinity chromatography technology	Taipale M (2014), Taipale M (2014)	2
NTRK1	1	CDC5L	2	affinity chromatography technology	Emdal KB (2015)	1
MNT	2	MAD1L1	2	affinity chromatography technology	Matsuoka Y (2008)	1
SCARA3	2	MAD1L1	2	affinity chromatography technology	Huttlin EL (2015)	1
MAD1L1	2	ZZEF1	5	biochemical	Kristensen AR (2012)	1
USP15	4	SENP3	1	enzymatic study	Loch CM (2012)	1
FOXJ2	3	MAD1L1	2	affinity chromatography technology	Li X (2015)	1
UBC	7	TSC22D3	1	affinity chromatography technology	Matsumoto M (2005)	1
NINL	1	HAUS1	0	two hybrid	Rolland T (2014)	1
RNF8	2	UBC	7	enzymatic study, enzymatic study, enzymatic study	Feng L (2012), Hodge CD (2015), Ho YK (2015)	3
MAD1L1	2	HAUS1	0	two hybrid	Rolland T (2014)	1
CDC5L	2	TRIP13	0	affinity chromatography technology	Lleres D (2010)	1
HNRNPL	3	USP15	4	affinity chromatography technology	Fei T (2017)	1
CDC20	1	UBC	7	enzymatic study, enzymatic study	Kelly A (2014), Craney A (2016)	2
MAD1L1	2	HDAC2	1	biochemical, affinity chromatography technology	Yoon YM (2004), Yoon YM (2004)	2
SNW1	0	TRIP13	0	affinity chromatography technology	Lleres D (2010)	1
NTRK1	1	SENP3	1	affinity chromatography technology	Emdal KB (2015)	1
SNW1	0	HSPA8	4	affinity chromatography technology	Lleres D (2010)	1
HDAC2	1	SNW1	0	two hybrid, two hybrid	Zhou S (2000), Zhou S (2000)	2
CDC27	2	MAD2L1BP	0	affinity chromatography technology	Westhorpe FG (2011)	1
MAD1L1	2	CCHCR1	2	two hybrid	Rolland T (2014)	1
METTL21C	0	MAD1L1	2	affinity chromatography technology	Cloutier P (2013)	1
NTRK1	1	TPR	5	affinity chromatography technology	Emdal KB (2015)	1
HSPA8	4	UBC	7	two hybrid	Stelzl U (2005)	1
NTRK1	1	SNW1	0	affinity chromatography technology	Emdal KB (2015)	1
SNW1	0	MAD1L1	2	affinity chromatography technology	Lleres D (2010)	1
MAD1L1	2	TRIP13	0	affinity chromatography technology	Wang K (2014)	1
MAD1L1	2	CDC20	1	affinity chromatography technology, affinity chromatography technology	Rodriguez-Bravo V (2014), Kelly A (2014)	2
SNW1	0	CDC27	2	affinity chromatography technology	Lleres D (2010)	1
ASB7	1	MAD1L1	2	affinity chromatography technology	Huttlin EL (2017)	1
SNW1	0	SIN3A	13	pull down	Zhou S (2000)	1
NTRK1	1	NONO	3	affinity chromatography technology	Emdal KB (2015)	1
TUBGCP4	3	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
MAD1L1	2	TSHZ3	6	two hybrid	Rolland T (2014)	1
NTRK1	1	USP15	4	affinity chromatography technology	Emdal KB (2015)	1
MAD2L1	0	MAD1L1	2	two hybrid, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Sironi L (2001), Murakumo Y (2000), Chen J (2001), Sironi L (2001), Sironi L (2001), Tipton AR (2011), De Antoni A (2005), De Antoni A (2005), Fava LL (2011), Fava LL (2011), Wang J (2011), Rodriguez-Bravo V (2014), Wang K (2014), Hein MY (2015), Sedgwick GG (2016), Sedgwick GG (2016), Yang M (2008), Kim S (2010), Kim S (2010), Theng SS (2014)	21
MAD1L1	2	MAD1L1	2	two hybrid	Rual JF (2005)	1
IKZF3	1	MAD1L1	2	affinity chromatography technology	Huttlin EL (2015)	1
SENP3	1	ZW10	2	affinity chromatography technology	Wang M (2016)	1
NTRK1	1	HSPA8	4	affinity chromatography technology	Emdal KB (2015)	1
MAD1L1	2	CCDC94	0	two hybrid	Rolland T (2014)	1
UBC	7	MAD1L1	2	pull down	Nathan JA (2013)	1
NTRK1	1	TRIP13	0	affinity chromatography technology	Emdal KB (2015)	1
HSPA8	4	MAD1L1	2	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	CDC27	2	affinity chromatography technology	Emdal KB (2015)	1
TPM3	0	MAD1L1	2	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
BAG5	0	MAD1L1	2	biochemical, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Taipale M (2014), Taipale M (2014), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	6
APC	5	TPR	5	two hybrid	Bandyopadhyay S (2010)	1
MAD1L1	2	RNF8	2	two hybrid	Rolland T (2014)	1
HNRNPL	3	MAD1L1	2	affinity chromatography technology	Fei T (2017)	1
CDC5L	2	TUBGCP4	3	affinity chromatography technology	Lleres D (2010)	1
CAVIN1	0	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
MAD1L1	2	TRIM29	2	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
IKZF3	1	HDAC2	1	affinity chromatography technology	Koipally J (2002)	1
MAD1L1	2	SIN3A	13	pull down	Icardi L (2012)	1
CAVIN1	0	ZZEF1	5	affinity chromatography technology	Huttlin EL (2017)	1
NRDC	3	MAD1L1	2	affinity chromatography technology	Li J (2012)	1
MAD2L1BP	0	CDC20	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Miniowitz-Shemtov S (2012), Westhorpe FG (2011), Westhorpe FG (2011), Lischetti T (2014), Kelly A (2014), Huttlin EL (2017), Izawa D (2012), Jia L (2016)	8
MAD1L1	2	STK24	3	biochemical	Wan C (2015)	1
SENP3	1	MAD1L1	2	affinity chromatography technology	Wang M (2016)	1
MAD1L1	2	ZSCAN32	10	two hybrid	Rolland T (2014)	1
MFAP1	3	COIL	1	two hybrid	Rolland T (2014)	1
CAVIN1	0	MAD1L1	2	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	SIN3A	13	affinity chromatography technology	Emdal KB (2015)	1
MAD2L1	0	MAD2L1BP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Habu T (2002), Westhorpe FG (2011), Fava LL (2011), Mapelli M (2006), Rolland T (2014), Hein MY (2015)	6
CDC20	1	HDAC1	4	affinity chromatography technology, biochemical	Yoon YM (2004), Yoon YM (2004)	2
METTL21C	0	HSPA8	4	affinity chromatography technology	Cloutier P (2013)	1
MAD1L1	2	TUBGCP4	3	two hybrid	Rual JF (2005)	1
MAD1L1	2	CWF19L2	2	two hybrid	Rolland T (2014)	1
TPM1	0	TPM3	0	biochemical, affinity chromatography technology, biochemical	Havugimana PC (2012), Huttlin EL (2015), Wan C (2015)	3
CDC5L	2	STK24	3	affinity chromatography technology	Lleres D (2010)	1
HNRNPL	3	PSMA1	1	affinity chromatography technology	Fei T (2017)	1
MAD1L1	2	LGALSL	0	two hybrid	Rolland T (2014)	1
ZW10	2	MAD2L1	0	imaging technique	Kops GJ (2005)	1
TPM1	0	MAD1L1	2	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
NINL	1	TUBGCP4	3	affinity chromatography technology	Casenghi M (2003)	1
USP15	4	UBC	7	pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down	Hetfeld BK (2005), Bremm A (2010), Komander D (2009), Loch CM (2012), Herhaus L (2014), Wauer T (2015), Das T (2017), Zhang X (2017), Kwasna D (2018)	9
CDC20	1	MAD2L1	0	affinity chromatography technology, two hybrid, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, unspecified method, pull down, affinity chromatography technology	Zhang Y (2001), Sihn CR (2003), Luo X (2000), Sironi L (2001), DAngiolella V (2003), Kallio MJ (2002), Wassmann K (1998), Kallio M (1998), Fang G (1998), Fang G (1998), Skoufias DA (2001), Nilsson J (2008), Privette LM (2008), Stegmeier F (2007), Ho CY (2010), Ho CY (2010), Mansfeld J (2011), Gao YF (2011), Braunstein I (2007), Visconti R (2010), Ma HT (2011), Townsend K (2009), Lee YJ (2008), DAngiolella V (2003), Tang Z (2001), Tang Z (2001), Sironi L (2001), Sironi L (2001), Ge S (2009), Mapelli M (2007), Tipton AR (2011), Mondal G (2006), Mondal G (2006), Westhorpe FG (2011), De Antoni A (2005), De Antoni A (2005), Kwan PS (2013), Katayama H (2012), Fava LL (2011), Santaguida S (2011), Mapelli M (2006), Eytan E (2013), Eytan E (2013), Hyun SY (2013), Han JS (2013), Rodriguez-Bravo V (2014), Fogeron ML (2013), Wang K (2014), Eytan E (2014), Hein JB (2014), Yen AH (2010), Yen AH (2010), Di Fiore B (2015), Hein MY (2015), Voets E (2015), Lischetti T (2014), Tipton AR (2013), Boekhout M (2015), Kelly A (2014), Craney A (2016), Sedgwick GG (2016), Sedgwick GG (2016), Izawa D (2012), Izawa D (2012), Jia L (2016), Jia L (2016), Kaisari S (2017), Yang M (2008), Kim S (2010), Kim S (2010)	70
MAD2L1BP	0	MAD1L1	2	affinity chromatography technology	Westhorpe FG (2011)	1
NTRK1	1	PSMA1	1	affinity chromatography technology	Emdal KB (2015)	1
CDC5L	2	CDC20	1	affinity chromatography technology	Lleres D (2010)	1
CDC5L	2	NONO	3	affinity chromatography technology	Lleres D (2010)	1
MFAP1	3	MAD1L1	2	two hybrid	Rolland T (2014)	1
MAD1L1	2	AMOTL2	5	two hybrid	Rual JF (2005)	1
CDC5L	2	HSPA8	4	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
NTRK1	1	MAD1L1	2	affinity chromatography technology	Emdal KB (2015)	1
CCHCR1	2	CAVIN1	0	affinity chromatography technology	Boldt K (2016)	1
ZADH2	0	MAD1L1	2	affinity chromatography technology	Huttlin EL (2017)	1
IKZF3	1	SIN3A	13	affinity chromatography technology	Koipally J (2002)	1
C6orf141	1	MAD1L1	2	affinity chromatography technology	Huttlin EL (2017)	1
MNT	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology	Matsuoka Y (2008), Matsuoka Y (2008)	2
NTRK1	1	NRDC	3	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	CAVIN1	0	pull down	Zhang X (2017)	1
UBC	7	APC	5	affinity chromatography technology	Matsumoto M (2005)	1
PSMA1	1	IKZF3	1	two hybrid	Rolland T (2014)	1
MAD1L1	2	USP15	4	two hybrid	Rolland T (2014)	1
SNW1	0	TEX11	0	two hybrid	Rolland T (2014)	1
CDC5L	2	CDC27	2	affinity chromatography technology	Lleres D (2010)	1
TSC22D3	1	MAD1L1	2	two hybrid	Rolland T (2014)	1
NTRK1	1	NUDC	1	affinity chromatography technology	Emdal KB (2015)	1
CDC20	1	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
NTRK1	1	ZW10	2	affinity chromatography technology	Emdal KB (2015)	1
TRIP13	0	MAD2L1BP	0	two hybrid, affinity chromatography technology, two hybrid, two hybrid, pull down	Rual JF (2005), Rual JF (2005), Stelzl U (2005), Venkatesan K (2009), Miniowitz-Shemtov S (2015)	5
TRIM29	2	RNF8	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Yang H (2015), Yang H (2015), Yang H (2015), Yang H (2015)	4
APC	5	MAD1L1	2	affinity chromatography technology	Hein MY (2015)	1
COIL	1	PSMA1	1	two hybrid	Lim J (2006)	1
CCHCR1	2	HAUS1	0	two hybrid	Rolland T (2014)	1
BMP1	5	MAD1L1	2	affinity chromatography technology	Huttlin EL (2017)	1
HDAC1	4	NONO	3	imaging technique, affinity chromatography technology, affinity chromatography technology	Dong X (2007), Liu L (2011), Zhang C (2008)	3
MAD2L1	0	APC	5	affinity chromatography technology	Fang G (1998)	1
CDC5L	2	TPR	5	affinity chromatography technology	Lleres D (2010)	1
NINL	1	CCHCR1	2	two hybrid, bioid	Rolland T (2014), Gupta GD (2015)	2
CCDC94	0	SNW1	0	affinity chromatography technology	Huttlin EL (2015)	1
HAUS1	0	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
ZSCAN32	10	HSPA8	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
FOXJ2	3	HDAC2	1	affinity chromatography technology	Li X (2015)	1
COIL	1	MAD1L1	2	two hybrid	Lim J (2006)	1
CDC27	2	MAD2L1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wassmann K (1998), Kallio M (1998), Li Y (1997), Li Y (1997), Lara-Gonzalez P (2011), Mansfeld J (2011), Visconti R (2010), Ma HT (2011), Sironi L (2001), Tipton AR (2011), Tipton AR (2011), Westhorpe FG (2011), Eytan E (2013), Lara-Gonzalez P (2011), Yen AH (2010), Hein MY (2015), Craney A (2016), Sedgwick GG (2016)	18
KCNAB3	0	MAD1L1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
NTRK1	1	HDAC2	1	affinity chromatography technology	Emdal KB (2015)	1
MAD1L1	2	SPATA2	2	two hybrid	Rolland T (2014)	1
HDAC2	1	SIN3A	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Zhang Y (2003), Fleischer TC (2003), Fleischer TC (2003), Hakimi MA (2003), Yang L (2003), Laherty CD (1997), Zhang Y (2002), Tong JK (1998), Zhang Y (2005), Nakamura T (2002), Sekhavat A (2007), Zou J (2004), Sun JM (2007), Xue Y (1998), Tsai SC (2002), Brandl A (2012), Bantscheff M (2011), Joshi P (2013), Wan C (2015), Hsu DS (2014)	20
TSC22D3	1	HDAC1	4	affinity chromatography technology	Bruscoli S (2010)	1
UBC	7	IKZF3	1	affinity chromatography technology	Gandhi AK (2014)	1
NTRK1	1	CWF19L2	2	affinity chromatography technology	Emdal KB (2015)	1