PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CAND1	2	UBC	7	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	RBM15B	4	affinity chromatography technology	Emdal KB (2015)	1
USP11	3	CS	1	affinity chromatography technology	Sowa ME (2009)	1
DDX19B	2	TRIM25	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CRY1	0	USP11	3	affinity chromatography technology	Papp SJ (2015)	1
USP11	3	SUMO2	0	enzymatic study	Hendriks IA (2015)	1
BMI1	0	NXF1	0	affinity chromatography technology	Cao Q (2014)	1
CRY1	0	MYCBP2	11	affinity chromatography technology	Papp SJ (2015)	1
XPC	1	H2AFX	1	affinity chromatography technology, affinity chromatography technology	Ray A (2009), Huttlin EL (2017)	2
TRIM25	5	LRP8	4	affinity chromatography technology	Choudhury NR (2017)	1
ZNF598	6	XPO7	5	affinity chromatography technology	Garzia A (2017)	1
CUL1	7	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
MAPK14	0	SMAD7	1	affinity chromatography technology, affinity chromatography technology	Edlund S (2003), Zhang S (2006)	2
SMAD6	9	SMAD7	1	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Topper JN (1997), Topper JN (1997), Topper JN (1997), Yan X (2016)	4
USP7	14	SUMO2	0	enzymatic study	Lecona E (2016)	1
SIRT7	1	H2AFX	1	affinity chromatography technology	Tsai YC (2012)	1
TRIM25	5	MAPK14	0	affinity chromatography technology	Choudhury NR (2017)	1
USP7	14	RAE1	0	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009)	2
ZUFSP	0	USP11	3	affinity chromatography technology	Hermanns T (2018)	1
CRY2	2	GARS	1	affinity chromatography technology	Papp SJ (2015)	1
KLHL13	0	USP11	3	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	ZNF598	6	affinity chromatography technology	Emdal KB (2015)	1
CDKN1A	1	SETDB1	3	two hybrid	Vinayagam A (2011)	1
FAF1	1	MYCBP2	11	affinity chromatography technology	Raman M (2015)	1
IFT43	0	USP11	3	affinity chromatography technology	Huttlin EL (2017)	1
CAND1	2	SEC23A	3	biochemical	Kristensen AR (2012)	1
SMAD7	1	TGFBR1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mochizuki T (2004), Asano Y (2004), Koinuma D (2003), Kavsak P (2000), Hayashi H (1997), Hayashi H (1997), Datta PK (2000), Wicks SJ (2005), Lallemand F (2005), Seong HA (2007), Yan X (2011), Cai Y (2012), Cai Y (2012), Seo SR (2004), Zhu L (2012), Zhu L (2012), Nakao A (1997), Yan X (2009), Kamiya Y (2010), Suzuki C (2002), Hsu HY (2014)	21
NTRK1	1	USP7	14	affinity chromatography technology	Emdal KB (2015)	1
PALB2	3	SNAI1	1	two hybrid	Arroyo R (2015)	1
NTRK1	1	UBC	7	affinity chromatography technology	Emdal KB (2015)	1
TP53	0	RANBP9	5	two hybrid	Chen J (2008)	1
USP11	3	KEAP1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009)	3
USP11	3	UBC	7	enzymatic study, pull down, pull down	Faesen AC (2011), Zhang X (2017), Kwasna D (2018)	3
TCEAL1	3	FAF1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RAPGEF2	5	UHRF1BP1	4	affinity chromatography technology	Hein MY (2015)	1
25885	0	POLR2E	0	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
TRIM25	5	NOTCH1	25	affinity chromatography technology	Choudhury NR (2017)	1
USP11	3	OTUD1	3	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	CTNNA1	7	affinity chromatography technology	Emdal KB (2015)	1
MAPK6	1	HSPH1	0	affinity chromatography technology	Rodriguez J (2016)	1
SORT1	1	USP15	4	affinity chromatography technology	Hein MY (2015)	1
XIAP	0	PGAM5	4	enzymatic study, pull down, affinity chromatography technology	Zhuang M (2013), Zhuang M (2013), Zhuang M (2013)	3
CUL1	7	RAE1	0	affinity chromatography technology	Bennett EJ (2010)	1
NOTCH1	25	USP15	4	affinity chromatography technology	Yatim A (2012)	1
TP53	0	H2AFX	1	affinity chromatography technology, affinity chromatography technology	Al Rashid ST (2005), Al Rashid ST (2005)	2
NTRK1	1	GIGYF2	7	affinity chromatography technology	Emdal KB (2015)	1
RNF4	1	PML	7	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, enzymatic study, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, protein complementation assay	Bruderer R (2011), Haekli M (2005), Percherancier Y (2009), Tatham MH (2008), Maroui MA (2012), Maroui MA (2012), Li YJ (2012), Kuo CY (2014), Kuo CY (2014), Weisshaar SR (2008), Sahin U (2014)	11
RAE1	0	CS	1	affinity chromatography technology	Sowa ME (2009)	1
OSBP	4	USP11	3	biochemical	Kristensen AR (2012)	1
MAP1LC3C	0	USP11	3	affinity chromatography technology	Behrends C (2010)	1
NOTCH1	25	XIAP	0	affinity chromatography technology, affinity chromatography technology	Liu WH (2007), Liu WH (2007)	2
USP11	3	MYO6	3	affinity chromatography technology	Sowa ME (2009)	1
TCEAL1	3	TCEAL4	0	affinity chromatography technology	Sowa ME (2009)	1
TP53	0	TEAD2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SORT1	1	USP11	3	affinity chromatography technology	Hein MY (2015)	1
DYRK1B	1	TCEAL1	3	affinity chromatography technology	Varjosalo M (2013)	1
SIRT7	1	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Tsai YC (2012), Jiang L (2017), Jiang L (2017), Jiang L (2017), Jiang L (2017), Jiang L (2017)	6
USP11	3	ZNF598	6	affinity chromatography technology	Hein MY (2015)	1
NTRK1	1	HSPH1	0	affinity chromatography technology	Emdal KB (2015)	1
STK11	2	USP11	3	affinity chromatography technology	Brajenovic M (2004)	1
CHEK1	2	XRCC5	5	affinity chromatography technology	Goudelock DM (2003)	1
BMI1	0	TP53	0	affinity chromatography technology, affinity chromatography technology	Calao M (2012), Yin J (2013)	2
TRIM25	5	UBA1	1	affinity chromatography technology	Pauli EK (2014)	1
MOV10	6	CLK3	0	affinity chromatography technology	Castello A (2012)	1
USP11	3	PGAM5	4	affinity chromatography technology	Sowa ME (2009)	1
MAPK14	0	TCEAL1	3	affinity chromatography technology	Varjosalo M (2013)	1
OTUD1	3	TP53	0	affinity chromatography technology, affinity chromatography technology	Piao S (2017), Piao S (2017)	2
USP11	3	XPO7	5	biochemical	Kristensen AR (2012)	1
USP11	3	ESPL1	2	affinity chromatography technology	Hein MY (2015)	1
PPP1R16B	2	ZNF24	1	affinity chromatography technology	Huttlin EL (2017)	1
UBC	7	RAE1	0	affinity chromatography technology	Matsumoto M (2005)	1
PRMT3	1	XPO7	5	biochemical	Kristensen AR (2012)	1
OTUD5	2	USP11	3	affinity chromatography technology	Sowa ME (2009)	1
CUL1	7	FARSA	6	affinity chromatography technology	Bennett EJ (2010)	1
WRNIP1	3	USP11	3	affinity chromatography technology	Sowa ME (2009)	1
CRY2	2	CAND1	2	affinity chromatography technology	Papp SJ (2015)	1
RMND5A	0	USP11	3	affinity chromatography technology	Lampert F (2018)	1
XRCC5	5	EIF4B	3	biochemical	Kristensen AR (2012)	1
USP7	14	UHRF1	3	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Qin W (2011), Ma H (2012), Ma H (2012), Ma H (2012), Chen H (2013), Nishiyama A (2013), Hein MY (2015), Zhang ZM (2015), Zhang ZM (2015), Zhang ZM (2015), Pfoh R (2015), Pfoh R (2015), Ferry L (2017)	18
ZNF24	1	ZNHIT3	0	two hybrid	Ravasi T (2010)	1
MAP1LC3C	0	UBC	7	imaging technique	Liu X (2017)	1
CUL4B	8	PGAM5	4	affinity chromatography technology	Bennett EJ (2010)	1
USP11	3	BUB3	0	affinity chromatography technology	Sowa ME (2009)	1
CBX8	3	MOV10	6	affinity chromatography technology	Vandamme J (2011)	1
RAE1	0	FAF1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Raman M (2015), Raman M (2015), Raman M (2015)	4
XIAP	0	SSX2IP	0	two hybrid	Rolland T (2014)	1
RNF2	1	RAD50	3	affinity chromatography technology	Cao Q (2014)	1
SIRT7	1	MOV10	6	affinity chromatography technology	Tsai YC (2012)	1
ZNF598	6	ATAD3B	5	affinity chromatography technology	Garzia A (2017)	1
MOV10	6	ESPL1	2	affinity chromatography technology	Castello A (2012)	1
PPP1R16B	2	KLHL13	0	affinity chromatography technology	Huttlin EL (2017)	1
RAE1	0	MYCBP2	11	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015)	2
NTRK1	1	USP11	3	affinity chromatography technology	Emdal KB (2015)	1
CAND1	2	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
RNF2	1	XRCC5	5	affinity chromatography technology	Cao Q (2014)	1
HSPH1	0	XPO7	5	biochemical	Kristensen AR (2012)	1
UBC	7	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Matsumoto M (2005), Bennett EJ (2010), Bish RA (2007), Wu K (2016)	4
NUP153	1	XPO7	5	pull down	Kutay U (2000)	1
MAPK6	1	TCEAL1	3	affinity chromatography technology	Rodriguez J (2016)	1
USP11	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Maertens GN (2010), Maertens GN (2010), Ma H (2012), Hein MY (2015)	7
UBE2Q1	0	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down	Shafiee SM (2015), Shafiee SM (2015), Shafiee SM (2015)	3
NXF1	0	USP11	3	affinity chromatography technology	Castello A (2012)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
UHRF1	3	TP53	0	affinity chromatography technology, pull down, pull down, enzymatic study	Ma J (2015), Ma J (2015), Ma J (2015), Ma J (2015)	4
TCEAL4	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Hein MY (2015), Hein MY (2015)	3
MOV10	6	OTUD5	2	affinity chromatography technology	Castello A (2012)	1
UBA1	1	CHEK1	2	pull down	Tan X (2015)	1
KEAP1	0	BRCA2	6	affinity chromatography technology, affinity chromatography technology	Ma J (2012), Lu K (2017)	2
UBC	7	ATAD3B	5	affinity chromatography technology	Bish RA (2007)	1
H2AFX	1	PML	7	affinity chromatography technology	Dittmann K (2011)	1
RNF2	1	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
CAND1	2	POLR1B	2	affinity chromatography technology	Bennett EJ (2010)	1
PPP1R16B	2	TGFBR1	2	affinity chromatography technology	Barrios-Rodiles M (2005)	1
MAPK14	0	DYRK1B	1	enzymatic study	Lee K (2000)	1
ELMSAN1	4	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
UBC	7	NEDD8	0	affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography	Matsumoto M (2005), Bennett EJ (2010), Singh RK (2012), Singh RK (2012)	4
SUMO2	0	SEC23A	3	biochemical	Wan C (2015)	1
ATOH1	2	MYCBP2	11	affinity chromatography technology	Cheng YF (2016)	1
MAPK6	1	MYCBP2	11	affinity chromatography technology	Rodriguez J (2016)	1
UBC	7	XPC	1	affinity chromatography technology	Bish RA (2007)	1
USP15	4	USP7	14	enzymatic study	Loch CM (2012)	1
CTNNA1	7	PRMT3	1	biochemical	Kristensen AR (2012)	1
NTRK1	1	SEC23A	3	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	WRNIP1	3	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down	Nathan JA (2013), Bish RA (2007), Bish RA (2007), Bish RA (2007), Bish RA (2007), Herhaus L (2015), Zhang X (2017)	7
TP53	0	TCEAL1	3	affinity chromatography technology	Huttlin EL (2015)	1
CUL4B	8	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
TEAD2	2	TRIP12	20	affinity chromatography technology	Li X (2015)	1
MAPK6	1	UBC	7	affinity chromatography technology	Rodriguez J (2016)	1
NUP153	1	RAE1	0	affinity chromatography technology	Hein MY (2015)	1
USP11	3	SETDB1	3	two hybrid	Stelzl U (2005)	1
NXF1	0	CS	1	affinity chromatography technology	Castello A (2012)	1
PCGF2	3	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
USP11	3	RAE1	0	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	SSX2IP	0	affinity chromatography technology	Sowa ME (2009)	1
TEAD2	2	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
EIF4B	3	PRMT3	1	biochemical	Kristensen AR (2012)	1
MAPK6	1	25885	0	affinity chromatography technology	Rodriguez J (2016)	1
CUL4B	8	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
MAPK6	1	FARSA	6	affinity chromatography technology	Rodriguez J (2016)	1
TCEAL1	3	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
NTRK1	1	PRMT3	1	affinity chromatography technology	Emdal KB (2015)	1
SSX2IP	0	TP53	0	bioid	Gupta GD (2015)	1
ATG10	0	USP11	3	affinity chromatography technology	Behrends C (2010)	1
PCK1	1	UBC	7	affinity chromatography technology	Jiang W (2011)	1
TCEAL1	3	UHRF1	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PGAM5	4	SETDB1	3	two hybrid	Stelzl U (2005)	1
EIF4B	3	POLR1C	2	biochemical	Havugimana PC (2012)	1
CHEK1	2	TP53	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study	Tian H (2002), Sengupta S (2004), Tian H (2002), Goudelock DM (2003), Shieh SY (2000)	5
SMAD7	1	TP53	0	affinity chromatography technology	Zhang S (2006)	1
NTRK1	1	SORT1	1	affinity chromatography technology	Emdal KB (2015)	1
RMND5A	0	PGAM5	4	affinity chromatography technology	Lampert F (2018)	1
TCEAL1	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015), Huttlin EL (2017)	3
RING1	2	TP53	0	affinity chromatography technology	Calao M (2012)	1
ECT2	2	CAND1	2	affinity chromatography technology	Woods NT (2012)	1
USP11	3	H2AFX	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Yu M (2016), Yu M (2016), Yu M (2016), Yu M (2016)	4
USP11	3	POLR1B	2	affinity chromatography technology	Sowa ME (2009)	1
FAF1	1	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Alexandru G (2008), Zhang L (2012), Zhang L (2012)	4
MOV10	6	ZNHIT3	0	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	RANBP9	5	affinity chromatography technology	Emdal KB (2015)	1
OSBP	4	CAND1	2	biochemical	Kristensen AR (2012)	1
SEC23A	3	XPO7	5	biochemical	Kristensen AR (2012)	1
USP11	3	DDX19B	2	affinity chromatography technology	Hein MY (2015)	1
TRIM25	5	PPP1R16B	2	affinity chromatography technology	Choudhury NR (2017)	1
25885	0	POLR1C	2	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Huttlin EL (2017)	5
ECT2	2	XRCC5	5	affinity chromatography technology	Woods NT (2012)	1
PML	7	CUL1	7	affinity chromatography technology	Shima Y (2008)	1
MOV10	6	XPO7	5	affinity chromatography technology	Castello A (2012)	1
TCEAL4	0	USP15	4	affinity chromatography technology	Hein MY (2015)	1
TEAD2	2	CDC27	2	affinity chromatography technology	Li X (2015)	1
USP11	3	EIF4B	3	affinity chromatography technology, biochemical	Sowa ME (2009), Kristensen AR (2012)	2
CTNNA1	7	EIF4B	3	biochemical	Kristensen AR (2012)	1
USP11	3	XPC	1	biochemical	Havugimana PC (2012)	1
USP7	14	BUB3	0	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	UHRF1BP1	4	affinity chromatography technology	Hein MY (2015)	1
CUL4B	8	MYCBP2	11	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	OSBP	4	affinity chromatography technology	Emdal KB (2015)	1
CDKN1A	1	AMOT	6	affinity chromatography technology	Fogeron ML (2013)	1
PCK1	1	GIGYF2	7	affinity chromatography technology	Jiang W (2011)	1
USP7	14	CBX8	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
SEC23A	3	PRMT3	1	biochemical	Kristensen AR (2012)	1
TRIM25	5	FOXJ3	3	affinity chromatography technology	Choudhury NR (2017)	1
USP15	4	IVNS1ABP	0	affinity chromatography technology	Boldt K (2016)	1
NXF1	0	TEAD2	2	affinity chromatography technology	Castello A (2012)	1
OTUD1	3	UBC	7	enzymatic study, pull down	Mevissen TE (2013), Kwasna D (2018)	2
SIRT7	1	MYCBP2	11	affinity chromatography technology	Tsai YC (2012)	1
CDKN1A	1	FAF1	1	two hybrid	Vinayagam A (2011)	1
UBC	7	UBA1	1	affinity chromatography technology, unspecified method, x-ray crystallography, biochemical, affinity chromatography technology, pull down	Nicassio F (2007), Zhao B (2012), Schaefer A (2014), Schaefer A (2014), Bish RA (2007), Zhang X (2017)	6
BMI1	0	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010), de Bie P (2010), Lecona E (2015), Lecona E (2015)	6
FOXJ3	3	USP11	3	affinity chromatography technology	Li X (2015)	1
FOXJ3	3	TP53	0	affinity chromatography technology	Li X (2015)	1
SIRT7	1	TRIP12	20	affinity chromatography technology	Tsai YC (2012)	1
UBC	7	AMOT	6	affinity chromatography technology	Matsumoto M (2005)	1
PIK3C3	1	USP11	3	affinity chromatography technology	Behrends C (2010)	1
PPP1R16B	2	USP11	3	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
SNAI1	1	RING1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Chen J (2014), Chen J (2014), Chen J (2014), Chen J (2014)	4
CUL1	7	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
WRAP53	1	USP7	14	affinity chromatography technology, affinity chromatography technology	Sun Y (2017), Sun Y (2017)	2
SIRT7	1	MRE11	3	affinity chromatography technology	Tsai YC (2012)	1
CUL1	7	FBXO45	1	affinity chromatography technology	Reitsma JM (2017)	1
MAPK6	1	ZNF24	1	affinity chromatography technology	Rodriguez J (2016)	1
RING1	2	RNF2	1	pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cao R (2005), Gearhart MD (2006), Wang H (2004), Trojer P (2011), Gao Z (2012), Gao Z (2012), Cao Q (2014), Hein MY (2015)	8
USP11	3	RAD50	3	affinity chromatography technology	Sowa ME (2009)	1
MAPK6	1	HNRNPD	3	two hybrid	Vinayagam A (2011)	1
USP11	3	HSPH1	0	biochemical	Kristensen AR (2012)	1
UHRF1	3	UHRF1BP1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Unoki M (2004), Unoki M (2004), Unoki M (2004)	3
ZNF24	1	TP53	0	two hybrid	Stelzl U (2005)	1
CDKN1A	1	USP11	3	affinity chromatography technology	Fogeron ML (2013)	1
BMI1	0	TRIM25	5	affinity chromatography technology	Cao Q (2014)	1
25885	0	POLR1B	2	affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Havugimana PC (2012), Wan C (2015), Hein MY (2015), Werner A (2015)	5
USP11	3	PML	7	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wu HC (2014), Wu HC (2014), Wu HC (2014), Wu HC (2014)	4
PRMT3	1	TP53	0	affinity chromatography technology	Lai Y (2011)	1
BRCA2	6	TP53	0	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Dong Y (2003), Marmorstein LY (1998)	4
USP7	14	RNF2	1	affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maertens GN (2010), Maertens GN (2010), de Bie P (2010), de Bie P (2010), de Bie P (2010), de Bie P (2010), de Bie P (2010), Gao Z (2012), Cao Q (2014), Lecona E (2015), Lecona E (2015), Hein MY (2015)	12
PCK1	1	USP11	3	affinity chromatography technology	Jiang W (2011)	1
CUL4B	8	USP4	3	affinity chromatography technology	Bennett EJ (2010)	1
PALB2	3	KEAP1	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Orthwein A (2015), Orthwein A (2015), Simhadri S (2014), Ma J (2012), Ma J (2012), Ma J (2012), Ma J (2012), Lu K (2017)	8
KEAP1	0	PGAM5	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Lo SC (2006), Lo SC (2006), Lo SC (2008), Lo SC (2008), Niture SK (2013), Lu K (2017)	7
BMI1	0	RNF2	1	biochemical, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, biochemical, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Cao R (2005), Cao R (2005), Ben-Saadon R (2006), Li Z (2006), Maertens GN (2009), Wei J (2006), Gao Z (2012), Gao Z (2012), Gao Z (2012), Gao Z (2012), Pan MR (2011), Pan MR (2011), Voncken JW (2005), Woodsmith J (2012), Voncken JW (2003), Woodsmith J (2012), Li Z (2006), Li Z (2006), McGinty RK (2014), Cao Q (2014), Cao Q (2014), Hein MY (2015), Balasubramanian S (2015), Taherbhoy AM (2015), Taherbhoy AM (2015), Abdouh M (2016), Sanchez A (2016), Wheaton K (2017), Hauri S (2016), Hauri S (2016)	30
TRIM25	5	ZNHIT3	0	affinity chromatography technology	Choudhury NR (2017)	1
USP11	3	USP11	3	pull down	Elliott PR (2011)	1
NXF1	0	RAE1	0	affinity chromatography technology, affinity chromatography technology	Bachi A (2000), Bachi A (2000)	2
UBC	7	MYO6	3	affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down	Matsumoto M (2005), Bish RA (2007), He F (2016), He F (2016), Zhang X (2017)	5
RELB	1	USP11	3	affinity chromatography technology	Bouwmeester T (2004)	1
RNF2	1	PGAM5	4	affinity chromatography technology	Cao Q (2014)	1
NEDD8	0	ELOB	1	affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010)	2
ECT2	2	PML	7	affinity chromatography technology	Woods NT (2012)	1
RBM15B	4	NXF1	0	affinity chromatography technology, pull down	Uranishi H (2009), Uranishi H (2009)	2
USP11	3	OSBPL10	1	affinity chromatography technology	Sowa ME (2009)	1
HSPH1	0	UBA1	1	pull down	Saito Y (2004)	1
SPTA1	10	PML	7	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
RNF4	1	SUMO2	0	fluorescent resonance energy transfe, affinity chromatography technology, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, pull down, x-ray crystallography, pull down, enzymatic study, pull down, pull down, pull down, affinity chromatography technology, enzymatic study	Geoffroy MC (2010), Bruderer R (2011), Bruderer R (2011), Tatham MH (2008), Sun H (2012), Tatham MH (2013), Erker Y (2013), Keusekotten K (2014), Kung CC (2014), Kung CC (2014), Xu Y (2014), Yin Y (2012), Tatham MH (2008), Xu Y (2014), Ouyang J (2015), Lecona E (2016)	16
FOXI2	1	XPO7	5	affinity chromatography technology	Li X (2015)	1
TCF4	26	POLR1C	2	two hybrid	Rolland T (2014)	1
SUMO2	0	RAD50	3	pull down	Ouyang J (2009)	1
TRIM25	5	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
TP53	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li M (2002), Li M (2002), Li M (2002), Li M (2002), Brooks CL (2007), Brooks CL (2007), Becker K (2007), Hu M (2006), Hu M (2006), Sarkari F (2010), Marchenko ND (2007), Epping MT (2011), Qing P (2011), Tang J (2006), Ma J (2010), Dai C (2011), Holowaty MN (2003), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Yi P (2013), Yi P (2013), Zhang J (2014), Fang Z (2013), Ye M (2015), Lim KH (2015), Lim KH (2015), Reddy BA (2014), Reddy BA (2014)	29
UBC	7	TCEAL1	3	pull down	Zhang X (2017)	1
BMI1	0	GIGYF2	7	affinity chromatography technology	Cao Q (2014)	1
TRIM27	2	BMI1	0	two hybrid	Woodsmith J (2012)	1
TCEAL1	3	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP7	14	TRIP12	20	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Liu X (2016), Liu X (2016)	3
FAF1	1	USP11	3	affinity chromatography technology	Raman M (2015)	1
USP7	14	EIF4B	3	affinity chromatography technology	Sowa ME (2009)	1
MAPK6	1	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
CAND1	2	MOV10	6	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	XPO7	5	affinity chromatography technology	Emdal KB (2015)	1
MAPK14	0	ELMSAN1	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Huttlin EL (2015), Huttlin EL (2017)	3
USP11	3	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Ke JY (2014), Ke JY (2014)	3
USP11	3	IVNS1ABP	0	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	KCTD6	2	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	GARS	1	biochemical	Kristensen AR (2012)	1
OSBPL10	1	KEAP1	0	affinity chromatography technology	Sowa ME (2009)	1
RING1	2	CBX8	3	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bardos JI (2000), Bardos JI (2000), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Rolland T (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	9
NOTCH1	25	CDC27	2	affinity chromatography technology	Yatim A (2012)	1
TP53	0	GIGYF2	7	affinity chromatography technology	Fogeron ML (2013)	1
CAND1	2	PCNP	0	affinity chromatography technology	Bennett EJ (2010)	1
RNF2	1	TRIM25	5	affinity chromatography technology	Cao Q (2014)	1
GARS	1	UBA1	1	biochemical	Havugimana PC (2012)	1
MAPK14	0	BMI1	0	enzymatic study	Srivastav RK (2011)	1
NOTCH1	25	USP7	14	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
USP4	3	USP15	4	affinity chromatography technology, enzymatic study, affinity chromatography technology	Zhang L (2012), Loch CM (2012), Das T (2017)	3
TRIM25	5	POLR1B	2	affinity chromatography technology	Choudhury NR (2017)	1
OSBP	4	CTNNA1	7	biochemical	Kristensen AR (2012)	1
TRIM25	5	USP11	3	affinity chromatography technology	Choudhury NR (2017)	1
CAND1	2	NXF1	0	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	MOGS	3	affinity chromatography technology	Emdal KB (2015)	1
USP11	3	KIAA0930	0	affinity chromatography technology	Sowa ME (2009)	1
H2AFX	1	BMI1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ginjala V (2011), Pan MR (2011), Pan MR (2011), Pan MR (2011)	4
NTRK1	1	EIF4B	3	affinity chromatography technology	Emdal KB (2015)	1
CDKN1A	1	USP4	3	two hybrid	Vinayagam A (2011)	1
NTRK1	1	UHRF1	3	affinity chromatography technology	Emdal KB (2015)	1
HNRNPD	3	GTSE1	3	two hybrid	Lehner B (2004)	1
TRIM25	5	CTNNA1	7	affinity chromatography technology	Choudhury NR (2017)	1
KEAP1	0	UBC	7	affinity chromatography technology, affinity chromatography technology, pull down	Gjyshi O (2015), Su C (2015), Zhang X (2017)	3
FAF1	1	HSPH1	0	biochemical	Kristensen AR (2012)	1
SEC23A	3	HSPH1	0	biochemical	Kristensen AR (2012)	1
PCGF2	3	USP11	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
UBC	7	MRE11	3	affinity chromatography technology	Matsumoto M (2005)	1
CUL4B	8	NXF1	0	biochemical	Wan C (2015)	1
GARS	1	XPO7	5	biochemical	Kristensen AR (2012)	1
RNF2	1	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gao Z (2012), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Cao Q (2014), Hein MY (2015), Hein MY (2015), Hauri S (2016), Hauri S (2016)	10
NXF1	0	25885	0	affinity chromatography technology	Castello A (2012)	1
SIRT7	1	TP53	0	affinity chromatography technology	Tsai YC (2012)	1
ZNF598	6	FARSA	6	affinity chromatography technology	Garzia A (2017)	1
USP11	3	MRE11	3	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	GIGYF2	7	affinity chromatography technology	Sowa ME (2009)	1
TRIM25	5	OTUD5	2	affinity chromatography technology	Choudhury NR (2017)	1
NTRK1	1	USP15	4	affinity chromatography technology	Emdal KB (2015)	1
RNF4	1	USP11	3	affinity chromatography technology	Hendriks IA (2015)	1
USP11	3	CBX8	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
NTRK1	1	PML	7	affinity chromatography technology	Emdal KB (2015)	1
BMI1	0	USP11	3	affinity chromatography technology, affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010), Maertens GN (2010)	3
CDKN1A	1	GIGYF2	7	affinity chromatography technology	Fogeron ML (2013)	1
LRP8	4	USP11	3	affinity chromatography technology	Hein MY (2015)	1
TP53	0	USP15	4	affinity chromatography technology, affinity chromatography technology	Liu WT (2016), Liu WT (2016)	2
HNRNPD	3	UHRF1BP1	4	affinity chromatography technology	Hein MY (2015)	1
DDX19B	2	XPO7	5	two hybrid	Stelzl U (2005)	1
USP11	3	POLR1C	2	affinity chromatography technology	Sowa ME (2009)	1
MIER2	0	RNF2	1	affinity chromatography technology	Huttlin EL (2015)	1
BMI1	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Facchino S (2010), Cao Q (2014)	2
USP11	3	NET1	1	affinity chromatography technology	Sowa ME (2009)	1
BMI1	0	PCNP	0	affinity chromatography technology	Cao Q (2014)	1
USP11	3	MPHOSPH9	1	affinity chromatography technology	Sowa ME (2009)	1
MOV10	6	PCNP	0	affinity chromatography technology	Castello A (2012)	1
USP11	3	TRIP12	20	affinity chromatography technology	Sowa ME (2009)	1
SMAD6	9	USP11	3	affinity chromatography technology, affinity chromatography technology	Herhaus L (2014), Herhaus L (2014)	2
DYRK1B	1	ATAD3B	5	affinity chromatography technology	Varjosalo M (2013)	1
H2AFX	1	UBC	7	affinity chromatography technology	Sharma N (2013)	1
TGFBR1	2	NOTCH1	25	affinity chromatography technology, affinity chromatography technology	Gudey SK (2014), Gudey SK (2014)	2
TCEAL1	3	TCEAL2	0	affinity chromatography technology	Sowa ME (2009)	1
ATG4C	1	USP11	3	affinity chromatography technology	Behrends C (2010)	1
MOV10	6	USP11	3	affinity chromatography technology	Castello A (2012)	1
SEC23A	3	CTNNA1	7	biochemical	Kristensen AR (2012)	1
NTRK1	1	CUL1	7	affinity chromatography technology	Emdal KB (2015)	1
SEC23A	3	GARS	1	biochemical	Kristensen AR (2012)	1
TRIM25	5	TGFBR1	2	affinity chromatography technology	Choudhury NR (2017)	1
SMAD6	9	TGFBR1	2	affinity chromatography technology, affinity chromatography technology	Hata A (1998), Kamiya Y (2010)	2
TRIM27	2	POLR1C	2	two hybrid	Rolland T (2014)	1
TCF4	26	USP11	3	affinity chromatography technology	Li X (2015)	1
SIRT7	1	NXF1	0	affinity chromatography technology	Tsai YC (2012)	1
TP53	0	SNAI1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lim SO (2010), Lim SO (2010), Liu T (2017)	3
NTRK1	1	CDC27	2	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	MAPK6	1	affinity chromatography technology	Choudhury NR (2017)	1
UBC	7	POLR1C	2	affinity chromatography technology	Matsumoto M (2005)	1
USP11	3	WRAP53	1	biochemical	Havugimana PC (2012)	1
NEDD8	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012)	4
MAPK6	1	BRCA2	6	affinity chromatography technology	Rodriguez J (2016)	1
IFT43	0	USP7	14	affinity chromatography technology	Huttlin EL (2017)	1
RMND5A	0	MYO6	3	affinity chromatography technology	Lampert F (2018)	1
TGFBR1	2	MAPK14	0	affinity chromatography technology	Sorrentino A (2008)	1
MOV10	6	MYO6	3	affinity chromatography technology	Castello A (2012)	1
H2AFX	1	RNF2	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Pan MR (2011), Pan MR (2011), Pan MR (2011), Pan MR (2011), Yang XX (2016)	5
ATOH1	2	SEC23A	3	affinity chromatography technology	Cheng YF (2016)	1
CTNNA1	7	XPO7	5	biochemical	Kristensen AR (2012)	1
TP53	0	STK11	2	affinity chromatography technology, fluorescent resonance energy transfe	Karuman P (2001), Ivanov AA (2017)	2
CDKN1A	1	MOGS	3	affinity chromatography technology	Fogeron ML (2013)	1
NXF1	0	LRP8	4	affinity chromatography technology	Castello A (2012)	1
TP53	0	MAPK14	0	protein complementation assay, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Srivastav RK (2011), Zhang S (2006), Mo JS (2010), Gong X (2010), Perfettini JL (2005), Perfettini JL (2005), Bulavin DV (1999), Bulavin DV (1999)	8
PCGF2	3	RING1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Elderkin S (2007), Maertens GN (2009), Gao Z (2012), Gao Z (2012), Woodsmith J (2012), Yu H (2011), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	9
USP11	3	EFHD2	2	affinity chromatography technology	Zhou Z (2017)	1
RAE1	0	EFHD2	2	biochemical	Wan C (2015)	1
USP11	3	RNF2	1	affinity chromatography technology, pull down	Maertens GN (2010), Maertens GN (2010)	2
CHEK1	2	USP11	3	genetic interference	Srivas R (2016)	1
MAPK6	1	POLR1C	2	affinity chromatography technology	Rodriguez J (2016)	1
CUL4B	8	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Bennett EJ (2010), Bennett EJ (2010), Hein MY (2015)	6
SIRT7	1	RAD50	3	affinity chromatography technology	Tsai YC (2012)	1
TRIM25	5	PTP4A2	1	affinity chromatography technology	Choudhury NR (2017)	1
CUL1	7	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
BMI1	0	PGAM5	4	affinity chromatography technology	Cao Q (2014)	1
RAE1	0	DDX19B	2	affinity chromatography technology	Sowa ME (2009)	1
51186	0	USP11	3	affinity chromatography technology	Ewing RM (2007)	1
TP53	0	PML	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Kurki S (2003), Kurki S (2003), Fogal V (2000), Fogal V (2000), Guo A (2000), Guo A (2000), Insinga A (2004), Chu Y (2011), Li Q (2011), Li Q (2011), Bernassola F (2005), Yang Q (2013), Yang Q (2013), Catalano A (2004), Chen TC (2014)	15
ZUFSP	0	UBC	7	enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, pull down, affinity chromatography technology, enzymatic study	Hermanns T (2018), Hermanns T (2018), Hermanns T (2018), Kwasna D (2018), Kwasna D (2018), Kwasna D (2018), Haahr P (2018), Haahr P (2018), Haahr P (2018)	9
TP53	0	MOGS	3	affinity chromatography technology	Fogeron ML (2013)	1
BMI1	0	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Maertens GN (2009), Maertens GN (2009), Maertens GN (2010), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Vandamme J (2011), Cao Q (2014), Hein MY (2015), Hauri S (2016), Hauri S (2016)	11
CAND1	2	USP15	4	affinity chromatography technology	Bennett EJ (2010)	1
FOXP3	1	WRNIP1	3	affinity chromatography technology	Li X (2015)	1
TRIM25	5	EIF4B	3	affinity chromatography technology	Choudhury NR (2017)	1
USP11	3	SEC23A	3	biochemical	Kristensen AR (2012)	1
USP11	3	UBA1	1	affinity chromatography technology	Hein MY (2015)	1
MAPK14	0	CDKN1A	1	enzymatic study, affinity chromatography technology	Kim GY (2002), Kim GY (2002)	2
TRIP12	20	UBC	7	affinity chromatography technology	Park Y (2009)	1
CRY1	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Busino L (2007), Papp SJ (2015), Huttlin EL (2017)	3
TCEAL4	0	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
SIRT7	1	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tsai YC (2012), Mo Y (2017), Mo Y (2017), Mo Y (2017)	4
TCEAL1	3	USP4	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP11	3	SIPA1L1	10	affinity chromatography technology	Sowa ME (2009)	1
ZNF598	6	CAND1	2	affinity chromatography technology	Garzia A (2017)	1
BRCA2	6	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Schoenfeld AR (2004), Schoenfeld AR (2004), Schoenfeld AR (2004), Schoenfeld AR (2004)	4
OSBPL9	4	OSBPL10	1	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	OSBPL9	4	affinity chromatography technology	Sowa ME (2009)	1
TCEAL1	3	TRIM25	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MOV10	6	PALB2	3	affinity chromatography technology	Castello A (2012)	1
GARS	1	NEDD8	0	pull down, affinity chromatography technology, pull down	Mo Z (2016), Mo Z (2016), Mo Z (2016)	3
USP11	3	GTSE1	3	affinity chromatography technology	Sowa ME (2009)	1
CBX8	3	SETDB1	3	two hybrid	Stelzl U (2005)	1
SNAI1	1	USP7	14	affinity chromatography technology	Liu T (2017)	1
MOV10	6	SEC61A1	1	affinity chromatography technology	Castello A (2012)	1
OSBPL10	1	CUL1	7	affinity chromatography technology	Sowa ME (2009)	1
PTP4A1	0	USP11	3	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
BMI1	0	RING1	2	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Satijn DP (1997), Satijn DP (1997), Satijn DP (1999), Satijn DP (1999), Cao R (2005), Cao R (2005), Maertens GN (2009), Wei J (2006), Wang H (2004), Gao Z (2012), Gao Z (2012), Boukarabila H (2009), Abdel-Wahab O (2012), Woodsmith J (2012), Rolland T (2014), Cao Q (2014), Hauri S (2016), Hauri S (2016)	18
CRY1	0	GARS	1	affinity chromatography technology	Papp SJ (2015)	1
HNRNPD	3	PRMT3	1	affinity chromatography technology	Hein MY (2015)	1
HNRNPD	3	CHEK1	2	biochemical	Wan C (2015)	1
PALB2	3	BRCA2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Hayakawa T (2010), Zhang F (2009), Sy SM (2009), Zhang F (2009), Xia B (2007), Xia B (2006), Xia B (2006), Xia B (2006), Sy SM (2009), Sy SM (2009), Sy SM (2009), Sy SM (2009), Zhang F (2012), Oliver AW (2009), Oliver AW (2009), Oliver AW (2009), Anantha RW (2013), Bleuyard JY (2012), Brough R (2012), Orthwein A (2015), Trego KS (2016), Trego KS (2016), Trego KS (2016), Simhadri S (2014), Byrd PJ (2016), Park JY (2014), Park JY (2014), Ma J (2012), Ma J (2012), Luijsterburg MS (2017), Luijsterburg MS (2017), Foo TK (2017)	32
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
SMAD7	1	USP15	4	affinity chromatography technology	Eichhorn PJ (2012)	1
FAF1	1	SEC23A	3	biochemical	Kristensen AR (2012)	1
NEDD8	0	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
TGFBR1	2	USP11	3	affinity chromatography technology	Al-Salihi MA (2012)	1
BUB3	0	UBA1	1	two hybrid	Wang J (2011)	1
XIAP	0	UBC	7	x-ray crystallography, pull down, pull down, pull down	Tse MK (2011), Gyrd-Hansen M (2008), Gyrd-Hansen M (2008), Nakatani Y (2012)	4
ATG10	0	USP7	14	affinity chromatography technology	Behrends C (2010)	1
NTRK1	1	OSBPL9	4	affinity chromatography technology	Emdal KB (2015)	1
USP11	3	PKN2	6	affinity chromatography technology	Sowa ME (2009)	1
CUL4B	8	EIF4B	3	biochemical	Kristensen AR (2012)	1
CUL1	7	CHEK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu S (2009), Huh J (2013), Zhang YW (2005)	3
XIAP	0	FAF1	1	two hybrid, pull down, affinity chromatography technology, imaging technique	Caballero-Lopez MJ (2017), Caballero-Lopez MJ (2017), Caballero-Lopez MJ (2017), Caballero-Lopez MJ (2017)	4
NTRK1	1	HNRNPD	3	affinity chromatography technology	Emdal KB (2015)	1
DYRK1B	1	RANBP9	5	pull down, affinity chromatography technology, two hybrid	Zou Y (2003), Zou Y (2003), Zou Y (2003)	3
WRAP53	1	XPC	1	biochemical	Havugimana PC (2012)	1
RAPGEF2	5	UBC	7	affinity chromatography technology	Kim TY (2014)	1
USP11	3	SEC61A1	1	affinity chromatography technology	Sowa ME (2009)	1
TRIM25	5	SEC23A	3	affinity chromatography technology	Choudhury NR (2017)	1
RANBP9	5	USP11	3	two hybrid, pull down, affinity chromatography technology	Ideguchi H (2002), Ideguchi H (2002), Ideguchi H (2002)	3
FOXI2	1	USP11	3	affinity chromatography technology	Li X (2015)	1
TRIM25	5	CS	1	affinity chromatography technology	Choudhury NR (2017)	1
PCGF2	3	CBX8	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Elderkin S (2007), Maertens GN (2009), Maertens GN (2009), Gao Z (2012), Vandamme J (2011), Vandamme J (2011), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	9
NXF1	0	UBC	7	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	FARSA	6	affinity chromatography technology	Emdal KB (2015)	1
ZNF24	1	SETDB1	3	two hybrid	Stelzl U (2005)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
NEDD8	0	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
TRIM25	5	PGAM5	4	affinity chromatography technology	Choudhury NR (2017)	1
SPTA1	10	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
MIER2	0	BRCA2	6	affinity chromatography technology	Huttlin EL (2015)	1
MOV10	6	CS	1	affinity chromatography technology	Castello A (2012)	1
USP11	3	SPRYD3	1	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	ELOB	1	affinity chromatography technology	Hein MY (2015)	1
CUL4B	8	UBC	7	affinity chromatography technology, pull down	Bennett EJ (2010), Nathan JA (2013)	2
TP53	0	MOV10	6	affinity chromatography technology	Li X (2015)	1
MAPK6	1	RANBP9	5	two hybrid	Vinayagam A (2011)	1
IFT43	0	TCEAL1	3	affinity chromatography technology	Huttlin EL (2017)	1
HNRNPD	3	ESPL1	2	affinity chromatography technology	Hein MY (2015)	1
USP11	3	CDC27	2	affinity chromatography technology	Sowa ME (2009)	1
MRE11	3	RAD50	3	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Chiba N (2001), Chiba N (2001), Dolganov GM (1996), Dolganov GM (1996), Trujillo KM (1998), Goedecke W (1999), Zheng L (2009), Goldberg M (2003), Goldberg M (2003), Goldberg M (2003), Cho YW (2007), Cho YW (2007), Greenberg RA (2006), Alt JR (2005), Alt JR (2005), Havugimana PC (2012), Wan C (2015), Wijnhoven P (2015), Boldt K (2016), Suhasini AN (2013), Suhasini AN (2013), Lee KY (2015), Nicholson J (2017)	25
CDC27	2	BUB3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lara-Gonzalez P (2011), Mansfeld J (2011), Qiao R (2016), Huttlin EL (2017)	4
DYRK4	5	USP11	3	affinity chromatography technology	Varjosalo M (2013)	1
USP15	4	KEAP1	0	enzymatic study	Villeneuve NF (2013)	1
USP11	3	XRCC5	5	affinity chromatography technology	Zhou Z (2017)	1
PML	7	POLR2E	0	two hybrid	Ravasi T (2010)	1
SUMO2	0	XRCC5	5	pull down	Ouyang J (2009)	1
RANBP9	5	RMND5A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kobayashi N (2007), Kobayashi N (2007), Huttlin EL (2015), Huttlin EL (2017), Boldt K (2016), Lampert F (2018)	6
CHEK1	2	CDKN1A	1	affinity chromatography technology	Tian H (2002)	1
UHRF1	3	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ma H (2012), Ma H (2012), Ma H (2012)	3
NOTCH1	25	RING1	2	affinity chromatography technology	Yatim A (2012)	1
ZUFSP	0	RAD50	3	affinity chromatography technology	Kwasna D (2018)	1
NTRK1	1	XRCC5	5	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	KLHL13	0	pull down	Nathan JA (2013)	1
STK11	2	TRIM25	5	two hybrid	Arroyo R (2015)	1
USP11	3	NUP153	1	affinity chromatography technology	Sowa ME (2009)	1
NXF1	0	PCNP	0	affinity chromatography technology	Castello A (2012)	1
TRIM27	2	PML	7	affinity chromatography technology	Cao T (1998)	1
ZNF598	6	HSPH1	0	affinity chromatography technology	Garzia A (2017)	1
TP53	0	TCF4	26	pull down, affinity chromatography technology	Kotlyar M (2015), Li X (2015)	2
NTRK1	1	CS	1	affinity chromatography technology	Emdal KB (2015)	1
CRY2	2	USP11	3	affinity chromatography technology	Papp SJ (2015)	1
HNRNPD	3	USP11	3	affinity chromatography technology	Hein MY (2015)	1
MAPK6	1	RAD50	3	affinity chromatography technology	Rodriguez J (2016)	1
PTP4A2	1	PTP4A1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Huttlin EL (2017), Yadav L (2017)	3
NXF1	0	USP15	4	affinity chromatography technology	Castello A (2012)	1
TRIM25	5	GIGYF2	7	affinity chromatography technology	Choudhury NR (2017)	1
TP53	0	TCEAL4	0	affinity chromatography technology	Fogeron ML (2013)	1
SIRT7	1	SEC23A	3	affinity chromatography technology	Tsai YC (2012)	1
RNF2	1	MOV10	6	affinity chromatography technology	Cao Q (2014)	1
SMAD6	9	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Herhaus L (2014), Herhaus L (2014), Herhaus L (2014)	3
SETDB1	3	PML	7	affinity chromatography technology, affinity chromatography technology	Cho S (2011), Cho S (2011)	2
FOXP3	1	USP11	3	affinity chromatography technology	Li X (2015)	1
CRY2	2	USP7	14	affinity chromatography technology	Papp SJ (2015)	1
NTRK1	1	POLR1C	2	affinity chromatography technology	Emdal KB (2015)	1
NXF1	0	SEC61A1	1	affinity chromatography technology	Castello A (2012)	1
GTSE1	3	SEC23A	3	affinity chromatography technology	Hein MY (2015)	1
USP11	3	AMOT	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009)	3
TRIM25	5	USP7	14	affinity chromatography technology	Choudhury NR (2017)	1
H2AFX	1	HNRNPD	3	affinity chromatography technology	Yang X (2010)	1
SIRT7	1	CTNNA1	7	affinity chromatography technology	Tsai YC (2012)	1
RNF2	1	SNAI1	1	affinity chromatography technology, imaging technique, imaging technique, biochemical	Chen J (2014), Chen J (2014), Chen J (2014), Chen J (2014)	4
TRIM25	5	VGLL4	1	affinity chromatography technology	Choudhury NR (2017)	1
MOV10	6	UBC	7	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	BUB3	0	affinity chromatography technology	Emdal KB (2015)	1
RNF2	1	UBC	7	enzymatic study	Woodsmith J (2012)	1
CDC27	2	CDKN1A	1	affinity chromatography technology	Amador V (2007)	1
OSBPL10	1	PGAM5	4	affinity chromatography technology	Sowa ME (2009)	1
NOTCH1	25	RNF2	1	affinity chromatography technology	Yatim A (2012)	1
FAF1	1	UBC	7	pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, biochemical	Song EJ (2005), Lee JJ (2012), Song J (2009), Song J (2009), Song J (2009), Lee JJ (2013), Lee JJ (2013), Nathan JA (2013), Baron Y (2014), Alexandru G (2008), Lee JJ (2012)	11
NXF1	0	ESPL1	2	affinity chromatography technology	Castello A (2012)	1
CLK3	0	USP7	14	affinity chromatography technology	Varjosalo M (2013)	1
RMND5A	0	51186	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP15	4	UBC	7	pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, pull down	Hetfeld BK (2005), Bremm A (2010), Komander D (2009), Loch CM (2012), Herhaus L (2014), Wauer T (2015), Das T (2017), Zhang X (2017), Kwasna D (2018)	9
USP11	3	PRRC2B	9	affinity chromatography technology	Sowa ME (2009)	1
OTUD5	2	TP53	0	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, imaging technique, pull down	Sowa ME (2009), Luo J (2013), Luo J (2013), Luo J (2013), Luo J (2013), Luo J (2013), Park SY (2015), Park SY (2015), Park SY (2015)	9
USP11	3	PALB2	3	enzymatic study, affinity chromatography technology	Orthwein A (2015), Orthwein A (2015)	2
MAPK6	1	SUMO2	0	affinity chromatography technology	Rodriguez J (2016)	1
H2AFX	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo K (2008), Heo K (2008), Sand-Dejmek J (2011)	3
CDKN1A	1	TCF4	26	two hybrid	Rolland T (2014)	1
SPTA1	10	MRE11	3	affinity chromatography technology	Sridharan DM (2006)	1
UBC	7	DDX19B	2	pull down	Zhang X (2017)	1
NXF1	0	CRY2	2	affinity chromatography technology	Castello A (2012)	1
CRY2	2	MYCBP2	11	affinity chromatography technology	Papp SJ (2015)	1
ECT2	2	USP11	3	affinity chromatography technology	Woods NT (2012)	1
MAPK14	0	USP11	3	affinity chromatography technology	Varjosalo M (2013)	1
TGFBR1	2	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Eichhorn PJ (2012), Zhang L (2013), Herhaus L (2014)	3
NXF1	0	XPO7	5	affinity chromatography technology	Castello A (2012)	1
RNF4	1	UHRF1	3	affinity chromatography technology	Bruderer R (2011)	1
TRIM25	5	HNRNPD	3	affinity chromatography technology	Choudhury NR (2017)	1
H2AFX	1	BRCA2	6	affinity chromatography technology, affinity chromatography technology, pull down	Heo K (2008), Heo K (2008), Krum SA (2010)	3
TP53	0	XPC	1	affinity chromatography technology	Krzeszinski JY (2013)	1
TGFBR1	2	RANBP9	5	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Zhang J (2014), Zhang J (2014), Zhang J (2014), Zhang J (2014)	4
USP4	3	TGFBR1	2	pull down, affinity chromatography technology, enzymatic study	Zhang L (2012), Zhang L (2012), Zhang L (2012)	3
RNF2	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Calao M (2012), Wen W (2013), Wen W (2013)	3
USP7	14	RING1	2	affinity chromatography technology, pull down, affinity chromatography technology	Maertens GN (2010), de Bie P (2010), Hein MY (2015)	3
UBC	7	RANBP9	5	affinity chromatography technology	Matsumoto M (2005)	1
UHRF1	3	XRCC5	5	affinity chromatography technology	Ferry L (2017)	1
ZNHIT3	0	USP11	3	affinity chromatography technology	Cloutier P (2017)	1
USP11	3	TRIM27	2	affinity chromatography technology	Hein MY (2015)	1
USP4	3	MRE11	3	affinity chromatography technology, affinity chromatography technology	Wijnhoven P (2015), Wijnhoven P (2015)	2
NTRK1	1	TCF4	26	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	SUMO2	0	affinity chromatography technology	Sahin U (2014)	1
ZNF598	6	GIGYF2	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Morita M (2012), Morita M (2012), Morita M (2012), Garzia A (2017)	4
CRY2	2	CUL1	7	affinity chromatography technology	Busino L (2007)	1
RMND5A	0	HSPH1	0	affinity chromatography technology	Lampert F (2018)	1
DYRK1B	1	SIPA1L1	10	affinity chromatography technology	Varjosalo M (2013)	1
USP11	3	USP4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Zhang L (2012)	3
OSBPL10	1	WRNIP1	3	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	25885	0	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	ATAD3B	5	affinity chromatography technology	Sowa ME (2009)	1
VGLL4	1	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Zhang E (2017), Zhang E (2017), Huttlin EL (2017)	4
OSBP	4	PRMT3	1	biochemical	Kristensen AR (2012)	1
NTRK1	1	PGAM5	4	affinity chromatography technology	Emdal KB (2015)	1
USP7	14	CHEK1	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Qing P (2011), Zhang P (2014), Zhang P (2014), Tan X (2015), Alonso-de Vega I (2014)	5
SPTA1	10	RAD50	3	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
CAND1	2	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
CAND1	2	TRUB1	2	affinity chromatography technology	Bennett EJ (2010)	1
USP11	3	SEMA3B	0	affinity chromatography technology	Hein MY (2015)	1
CAND1	2	GARS	1	biochemical	Kristensen AR (2012)	1
NTRK1	1	WRNIP1	3	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	RNF4	1	affinity chromatography technology	Choudhury NR (2017)	1
CUL4B	8	TCEAL2	0	affinity chromatography technology	Bennett EJ (2010)	1
NTRK1	1	ATAD3B	5	affinity chromatography technology	Emdal KB (2015)	1
NTRK1	1	FAF1	1	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	PRMT3	1	affinity chromatography technology	Choudhury NR (2017)	1
STK11	2	H2AFX	1	affinity chromatography technology	So J (2015)	1
NTRK1	1	USP4	3	affinity chromatography technology	Emdal KB (2015)	1
CUL4B	8	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
NXF1	0	OSBP	4	affinity chromatography technology	Castello A (2012)	1
CIAO1	3	USP11	3	affinity chromatography technology	Ewing RM (2007)	1
NTRK1	1	CUL4B	8	affinity chromatography technology	Emdal KB (2015)	1
HSPH1	0	USP7	14	biochemical	Wan C (2015)	1
TRIM27	2	TP53	0	affinity chromatography technology, pull down, enzymatic study	Chu Y (2011), Chu Y (2011), Chu Y (2011)	3
SIRT7	1	25885	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ford E (2006), Ford E (2006), Tsai YC (2012), Tsai YC (2012), Tsai YC (2012)	5
FAF1	1	PRMT3	1	biochemical	Kristensen AR (2012)	1
FAF1	1	XPO7	5	biochemical	Kristensen AR (2012)	1
GIGYF2	7	SIPA1L1	10	affinity chromatography technology	Boldt K (2016)	1
TRIM25	5	CAND1	2	affinity chromatography technology	Choudhury NR (2017)	1
NXF1	0	SETDB1	3	affinity chromatography technology	Castello A (2012)	1
NTRK1	1	POLR1B	2	affinity chromatography technology	Emdal KB (2015)	1
RAPGEF2	5	XIAP	0	affinity chromatography technology	Hein MY (2015)	1
CRY1	0	XRCC5	5	affinity chromatography technology	Papp SJ (2015)	1
MAP1LC3C	0	PIK3C3	1	affinity chromatography technology	Behrends C (2010)	1
DYRK1B	1	USP11	3	affinity chromatography technology	Varjosalo M (2013)	1
TCEAL1	3	UBE2Q1	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
USP11	3	CNOT8	1	affinity chromatography technology	Hein MY (2015)	1
SORT1	1	XIAP	0	affinity chromatography technology	Hein MY (2015)	1
STK11	2	CRY2	2	two hybrid	Arroyo R (2015)	1
NTRK1	1	MYO6	3	affinity chromatography technology	Emdal KB (2015)	1
CRY1	0	UBA1	1	affinity chromatography technology	Papp SJ (2015)	1
NTRK1	1	SEC61A1	1	affinity chromatography technology	Emdal KB (2015)	1
SNAI1	1	USP11	3	affinity chromatography technology	Liu T (2017)	1
CUL1	7	SEC23A	3	affinity chromatography technology	Bennett EJ (2010)	1
USP11	3	UBE2Q1	0	affinity chromatography technology	Hein MY (2015)	1
MOV10	6	SETDB1	3	affinity chromatography technology	Castello A (2012)	1
USP11	3	MOGS	3	affinity chromatography technology	Hein MY (2015)	1
TCF4	26	25885	0	two hybrid	Rolland T (2014)	1
MIER2	0	USP11	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAPK6	1	SMAD6	9	two hybrid	Vinayagam A (2011)	1
NEDD8	0	CUL4B	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Norman JA (2006), Bennett EJ (2010), Bennett EJ (2010)	3
CUL4B	8	TP53	0	affinity chromatography technology	Thirunavukarasou A (2014)	1
CTNNA1	7	HSPH1	0	biochemical	Kristensen AR (2012)	1
USP11	3	FARSA	6	affinity chromatography technology	Sowa ME (2009)	1
CLK3	0	USP11	3	affinity chromatography technology	Varjosalo M (2013)	1
SIRT7	1	XRCC5	5	affinity chromatography technology	Tsai YC (2012)	1
CHEK1	2	XIAP	0	pull down, affinity chromatography technology, pull down	Galvan V (2004), Galvan V (2004), Galvan V (2004)	3
RNF2	1	UHRF1	3	affinity chromatography technology	Cao Q (2014)	1
SIRT7	1	PRRC2B	9	affinity chromatography technology	Tsai YC (2012)	1
NOTCH1	25	CAND1	2	affinity chromatography technology	Yatim A (2012)	1
RNF2	1	PIK3C3	1	affinity chromatography technology	Xia P (2014)	1
GARS	1	CTNNA1	7	biochemical	Kristensen AR (2012)	1
SIRT7	1	NUP153	1	affinity chromatography technology	Tsai YC (2012)	1
TP53	0	RAE1	0	affinity chromatography technology	Fogeron ML (2013)	1
MAPK14	0	STK11	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM25	5	FAF1	1	affinity chromatography technology	Choudhury NR (2017)	1
USP15	4	USP11	3	affinity chromatography technology	Sowa ME (2009)	1
RBM15B	4	USP11	3	biochemical	Havugimana PC (2012)	1
CRY1	0	CRY2	2	affinity chromatography technology, affinity chromatography technology	Papp SJ (2015), Huttlin EL (2017)	2
NXF1	0	MYO6	3	affinity chromatography technology	Castello A (2012)	1
TCEAL1	3	ZUFSP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017), Hermanns T (2018)	3
MOV10	6	LRP8	4	affinity chromatography technology	Castello A (2012)	1
UBC	7	FARSA	6	affinity chromatography technology	Matsumoto M (2005)	1
USP11	3	ZNF24	1	affinity chromatography technology	Sowa ME (2009)	1
POLR2E	0	POLR1C	2	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
CLK3	0	TP53	0	affinity chromatography technology	Varjosalo M (2013)	1
HSPH1	0	PRMT3	1	biochemical	Kristensen AR (2012)	1
UBC	7	USP4	3	affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down	Matsumoto M (2005), Faesen AC (2011), Song EJ (2010), Clerici M (2014), Kwasna D (2018)	5
NTRK1	1	MRE11	3	affinity chromatography technology	Emdal KB (2015)	1
USP11	3	ELMSAN1	4	affinity chromatography technology	Hein MY (2015)	1
CUL4B	8	TRIM27	2	affinity chromatography technology	Bennett EJ (2010)	1
SUMO2	0	SETDB1	3	two hybrid, two hybrid, pull down	Vinayagam A (2011), Goehler H (2004), Ouyang J (2009)	3
MOV10	6	25885	0	affinity chromatography technology	Castello A (2012)	1
POLR1B	2	POLR1C	2	biochemical, biochemical, affinity chromatography technology	Havugimana PC (2012), Wan C (2015), Huttlin EL (2017)	3
USP11	3	CTNNA1	7	biochemical	Kristensen AR (2012)	1
UHRF1	3	CUL1	7	affinity chromatography technology	Chen H (2013)	1
CRY1	0	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Papp SJ (2015), Papp SJ (2015), Papp SJ (2015)	3
OTUD5	2	UBC	7	pull down, enzymatic study, enzymatic study, pull down, pull down	Kayagaki N (2007), Huang OW (2012), Mevissen TE (2013), Zhang X (2017), Kwasna D (2018)	5
NTRK1	1	PIK3C3	1	affinity chromatography technology	Emdal KB (2015)	1
CUL4B	8	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
FOXP3	1	CDC27	2	affinity chromatography technology	Li X (2015)	1
SEC23A	3	EIF4B	3	biochemical	Kristensen AR (2012)	1
NXF1	0	NUP153	1	pull down, affinity chromatography technology	Herold A (2000), Hein MY (2015)	2
SUMO2	0	MRE11	3	pull down	Ouyang J (2009)	1
EIF4B	3	XPO7	5	biochemical	Kristensen AR (2012)	1
MZT1	1	USP11	3	affinity chromatography technology	Hein MY (2015)	1
USP7	14	TRIM27	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hayes SD (2012), Hein MY (2015), Zaman MM (2013), Zaman MM (2013)	4
USP7	14	XPC	1	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	He J (2014), He J (2014), He J (2014), He J (2014)	4
ZNF598	6	PGAM5	4	affinity chromatography technology	Garzia A (2017)	1
USP7	14	UBC	7	enzymatic study, enzymatic study, unspecified method, enzymatic study, pull down	Bremm A (2010), Faesen AC (2011), Ernst A (2013), Holowaty MN (2003), Kwasna D (2018)	5
USP11	3	MYCBP2	11	affinity chromatography technology	Sowa ME (2009)	1
NTRK1	1	KLHL13	0	affinity chromatography technology	Emdal KB (2015)	1
UBC	7	MYCBP2	11	affinity chromatography technology	Matsumoto M (2005)	1
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
TRIM25	5	SEMA3B	0	affinity chromatography technology	Choudhury NR (2017)	1
XRCC5	5	POLR2E	0	affinity chromatography technology	Matheos D (2002)	1
NOTCH1	25	USP11	3	affinity chromatography technology	Yatim A (2012)	1
MOV10	6	TEAD2	2	affinity chromatography technology	Castello A (2012)	1
TRIM25	5	XPO7	5	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
GTSE1	3	MYO6	3	affinity chromatography technology	Hein MY (2015)	1
RMND5A	0	CUL4B	8	affinity chromatography technology	Lampert F (2018)	1
NUP153	1	SUMO2	0	affinity chromatography technology	Hein MY (2015)	1
WRAP53	1	H2AFX	1	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Henriksson S (2014), Rassoolzadeh H (2015), Rassoolzadeh H (2015), Rassoolzadeh H (2015)	4
XRCC5	5	PRMT3	1	biochemical	Kristensen AR (2012)	1
ECT2	2	PGAM5	4	affinity chromatography technology	Woods NT (2012)	1
ZNF24	1	TRIM25	5	two hybrid	Ravasi T (2010)	1
USP11	3	PCNP	0	affinity chromatography technology	Hein MY (2015)	1
NEDD8	0	SEC23A	3	affinity chromatography technology	Bennett EJ (2010)	1
OSBP	4	EIF4B	3	biochemical	Kristensen AR (2012)	1
TRUB1	2	TCEAL1	3	affinity chromatography technology	Huttlin EL (2017)	1
ATOH1	2	USP11	3	affinity chromatography technology	Cheng YF (2016)	1
OSBP	4	XPO7	5	biochemical	Kristensen AR (2012)	1
TRIM25	5	ZNF598	6	affinity chromatography technology	Choudhury NR (2017)	1
EIF4B	3	NUP153	1	biochemical	Havugimana PC (2012)	1
RAPGEF2	5	USP11	3	affinity chromatography technology	Hein MY (2015)	1
CIAO1	3	MRE11	3	affinity chromatography technology	Stehling O (2013)	1
FBXO45	1	MYCBP2	11	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Saiga T (2009), Saiga T (2009), Chen X (2014), Chen X (2014), Chen X (2014), Chung FZ (2014), Chung FZ (2014), Chung FZ (2014), Boldt K (2016)	9
UHRF1	3	PML	7	affinity chromatography technology, affinity chromatography technology	Guan D (2012), Guan D (2012)	2
USP11	3	SPTA1	10	affinity chromatography technology	Zhou Z (2017)	1
CUL1	7	CAND1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Min KW (2003), Min KW (2003), Min KW (2003), Menon S (2008), Chew EH (2007), Min KW (2005), Min KW (2005), Min KW (2005), Hwang JW (2003), Hwang JW (2003), Mao X (2011), Chua YS (2011), Chua YS (2011), Tron AE (2012), Zheng J (2002), Zheng J (2002), Bornstein G (2006), Oshikawa K (2003), Oshikawa K (2003), Lee JE (2011), He YJ (2006), Emberley ED (2012), Choo YY (2011), Jonason JH (2007), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Liu J (2002), Liu J (2002), Liu J (2002), Liu J (2002), Korzeniewski N (2012), Pierce NW (2013), Kim AY (2008), Zhang S (2016), Tikhmyanova N (2017), Tikhmyanova N (2017), Reitsma JM (2017), Reitsma JM (2017)	41
NTRK1	1	RAD50	3	affinity chromatography technology	Emdal KB (2015)	1
SIRT7	1	XPO7	5	affinity chromatography technology	Tsai YC (2012)	1
MOV10	6	HNRNPD	3	affinity chromatography technology	Castello A (2012)	1
TRIM25	5	PML	7	affinity chromatography technology	Choudhury NR (2017)	1
MAPK6	1	USP11	3	affinity chromatography technology	Rodriguez J (2016)	1
PCGF2	3	RNF2	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Elderkin S (2007), Elderkin S (2007), Maertens GN (2009), Gao Z (2012), Gao Z (2012), Gao Z (2012), Endoh M (2012), Woodsmith J (2012), Woodsmith J (2012), Cao Q (2014), Taherbhoy AM (2015), Taherbhoy AM (2015), Huttlin EL (2017), Hauri S (2016), Hauri S (2016)	15
SMAD7	1	USP11	3	affinity chromatography technology, biochemical, affinity chromatography technology	Al-Salihi MA (2012), Al-Salihi MA (2012), Herhaus L (2014)	3
NTRK1	1	CAND1	2	affinity chromatography technology	Emdal KB (2015)	1
USP11	3	RING1	2	affinity chromatography technology	Maertens GN (2010)	1
ECT2	2	TP53	0	affinity chromatography technology	Woods NT (2012)	1
PTP4A2	1	USP11	3	affinity chromatography technology, bioid	Yadav L (2017), Yadav L (2017)	2
UBC	7	TRIM27	2	affinity chromatography technology	Matsumoto M (2005)	1
IVNS1ABP	0	HNRNPD	3	affinity chromatography technology	Tsai PL (2013)	1
UBC	7	SEC61A1	1	affinity chromatography technology	Matsumoto M (2005)	1
TRIM25	5	CLK3	0	affinity chromatography technology	Choudhury NR (2017)	1
SUMO2	0	PML	7	imaging technique, two hybrid, pull down	Cuchet-Lourenco D (2011), Li C (2017), Li C (2017)	3
USP11	3	TCEAL2	0	affinity chromatography technology	Sowa ME (2009)	1
RNF2	1	POLR2E	0	affinity chromatography technology	Cao Q (2014)	1
RNF2	1	25885	0	affinity chromatography technology	Cao Q (2014)	1
USP7	14	PML	7	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Sivachandran N (2010), Sarkari F (2011), Sarkari F (2011), Hein MY (2015)	4
SNAI1	1	NOTCH1	25	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lim SO (2011), Lim SO (2011), Lim SO (2011), Lim SO (2011)	4
POLR1B	2	POLR2E	0	biochemical, affinity chromatography technology	Wan C (2015), Huttlin EL (2017)	2
TCEAL4	0	TCEAL2	0	affinity chromatography technology	Sowa ME (2009)	1
PCGF2	3	BMI1	0	affinity chromatography technology	Huttlin EL (2017)	1
USP11	3	XIAP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Zhou Z (2017), Zhou Z (2017), Zhou Z (2017)	4
USP11	3	FBXO45	1	affinity chromatography technology	Sowa ME (2009)	1
USP11	3	POLR2E	0	affinity chromatography technology	Sowa ME (2009)	1
USP4	3	RAD50	3	affinity chromatography technology	Wijnhoven P (2015)	1
NTRK1	1	UBA1	1	affinity chromatography technology	Emdal KB (2015)	1
TRIM25	5	USP15	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Pauli EK (2014), Pauli EK (2014), Pauli EK (2014), Pauli EK (2014)	4
TP53	0	MYO6	3	affinity chromatography technology	Horikawa I (2014)	1
OSBP	4	GARS	1	biochemical	Kristensen AR (2012)	1
SIRT7	1	PGAM5	4	affinity chromatography technology	Tsai YC (2012)	1
SIRT7	1	USP11	3	affinity chromatography technology	Tsai YC (2012)	1
H2AFX	1	RAD50	3	imaging technique, affinity chromatography technology	Paull TT (2000), Lukas C (2004)	2
TRUB1	2	USP11	3	affinity chromatography technology	Huttlin EL (2017)	1
NTRK1	1	GARS	1	affinity chromatography technology	Emdal KB (2015)	1
RNF4	1	UBC	7	enzymatic study, enzymatic study	Groocock LM (2014), Branigan E (2015)	2
TCEAL4	0	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Hein MY (2015), Hein MY (2015)	5
NTRK1	1	MOV10	6	affinity chromatography technology	Emdal KB (2015)	1
TEAD2	2	USP11	3	affinity chromatography technology	Li X (2015)	1
H2AFX	1	MRE11	3	affinity chromatography technology, imaging technique, affinity chromatography technology	Lukas C (2004), Kobayashi J (2002), Kobayashi J (2002)	3
USP11	3	PRMT3	1	biochemical	Kristensen AR (2012)	1
SIRT7	1	GIGYF2	7	affinity chromatography technology	Tsai YC (2012)	1
OSBP	4	SEC23A	3	biochemical	Kristensen AR (2012)	1
TRIM25	5	RAPGEF2	5	affinity chromatography technology	Choudhury NR (2017)	1
NOTCH1	25	RANBP9	5	affinity chromatography technology	Yatim A (2012)	1
NXF1	0	HNRNPD	3	affinity chromatography technology	Castello A (2012)	1