Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SYN3 rs9621532 AA ranibizumab efficacy no Patients underwent 5 monthly injections. Good response at month 5 was defined as best-corrected visual acuity improvement of >= 8 Early Treatment Diabetic Retinopathy Study (ETDRS) letters from baseline. Bonferroni correction for multiple testing. Please note alleles have been complemented to the plus chromosomal strand. Genotype AA is not associated with response to ranibizumab in people with Macular Degeneration as compared to genotype AC. 23842101 1184511472