Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
ADAM33 80332 CHEMBL148169 CHEMBL148169 inhibitor GuideToPharmacologyInteractions

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
ADAM33 rs2787094 CC ustekinumab efficacy yes as measured by PASI75 at 4 months and adjusted for weight and FDR. Caution this is C/G SNP in gene on minus strand, it appeared from looking at other minus strand genes that all variants in the paper were measured on plus strand so results are reported as stated as in the paper and not complemented. Genotype CC is associated with decreased response to ustekinumab in people with Psoriasis as compared to genotypes CG + GG. 27977334 1448594435