PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
NFKB1	2	TNFAIP3	3	affinity chromatography technology	Lapid D (2017)	1
NFKB1	2	REL	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Huttlin EL (2015), Li X (2015), Huttlin EL (2017)	4
NFKB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Deng WG (2003), Deng WG (2003), Furia B (2002), Wang H (2010), Wang H (2010), Sen GS (2011), Hassa PO (2003), Hassa PO (2003), Deng WG (2003)	9
TNFAIP3	3	TNIP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Van Huffel S (2001), Dong G (2011), Dong G (2011), Bohgaki M (2008), Klinkenberg M (2001)	5
UBC	7	USP35	3	pull down	Kwasna D (2018)	1
SMURF1	4	XPO1	8	affinity chromatography technology	Tajima Y (2003)	1
MKNK1	0	APP	1	pull down	Olah J (2011)	1
SRPK2	1	CHUK	5	enzymatic study	Varjosalo M (2013)	1
STK11	2	TNIP2	1	two hybrid, two hybrid, affinity chromatography technology, pull down	Liu WK (2003), Chien CY (2003), Liu WK (2003), Liu WK (2003)	4
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
NFKB2	3	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Scheinman RI (1993), Scheinman RI (1993), Yang CH (2005), Leung CH (2006)	5
RELB	1	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
MKNK1	0	MAPK1	1	pull down, two hybrid, pull down	Waskiewicz AJ (1997), Waskiewicz AJ (1997), Smith JA (2000)	3
UBC	7	IKBKB	1	pull down	Zhang X (2017)	1
XPO1	8	TNIP2	1	affinity chromatography technology	Kirli K (2015)	1
IKBKB	1	TNFAIP3	3	enzymatic study, affinity chromatography technology	Zetoune FS (2001), Xiong Y (2011)	2
EP300	36	UBC	7	enzymatic study, affinity chromatography technology	Delvecchio M (2013), Kirilyuk A (2012)	2
NFKB1	2	NFKB2	3	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bouwmeester T (2004), Bouwmeester T (2004), Wang J (2011), Li X (2015)	4
XPO1	8	MAP3K8	2	affinity chromatography technology	Kirli K (2015)	1
RELA	1	UBC	7	affinity chromatography technology	Schweitzer K (2015)	1
NFKB1	2	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Palvimo JJ (1996), Dhar SK (2006), Williams SA (2006), Williams SA (2006), Hassa PO (2005), Hassa PO (2005), Sasaki CY (2005), Jeon YJ (2010), Urban MB (1991), Beauchef G (2012), Ryo A (2003), Burstein E (2005), Beinke S (2002), Sharif-Askari E (2010), Mifflin RC (2002), Nie M (2003), Nehra R (2010), Wang J (2011), Mellits KH (1993), Gallois C (1998), Milanovic M (2013), Milanovic M (2013), Kwon JH (2003), Cimen I (2011), Saha RN (2007), Wi SM (2014), Wi SM (2014), Hochrainer K (2012), Longoni N (2013), Li X (2015)	31
REL	5	RELB	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO1	8	MKNK1	0	affinity chromatography technology	Kirli K (2015)	1
NFKB2	3	REL	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Scheinman RI (1993), Huttlin EL (2015), Huttlin EL (2017)	4
TNFAIP3	3	UBC	7	x-ray crystallography, enzymatic study, pull down, pull down, x-ray crystallography, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, pull down, enzymatic study, x-ray crystallography, pull down	Bosanac I (2010), Bremm A (2010), Fenner BJ (2009), Tokunaga F (2012), Tokunaga F (2012), Verhelst K (2012), Mevissen TE (2013), Komander D (2009), Evans PC (2004), Skaug B (2011), Bohgaki M (2008), Boone DL (2004), Mevissen TE (2016), Mevissen TE (2016)	14
IKBKG	0	CHUK	5	pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Agou F (2002), Chen G (2002), Deng L (2000), Shifera AS (2008), Fenner BJ (2010), Rothwarf DM (1998), Rothwarf DM (1998), Hasegawa M (2008), Liu J (2009), Li S (2011), Li S (2011), Xia X (2011), Kensche T (2012), May MJ (2002), Wu ZH (2006), Wu ZH (2006), Palkowitsch L (2008), Le Page C (2001), Le Page C (2001), Huang TT (2002), Sebban-Benin H (2007), Tegethoff S (2003), Hai T (2006), Ammirante M (2010), McKenzie FR (2000), Solt LA (2007), Li XH (2001), Rottenberg S (2002), Poyet JL (2000), Poyet JL (2000), Stilo R (2004), Marienfeld RB (2006), Marienfeld RB (2006), Strnad J (2006), Strnad J (2006), Funakoshi-Tago M (2005), Shibata Y (2012), Wu X (2007), Stehlik C (2002), Ryzhakov G (2007), Chen RA (2008), Marinis JM (2012), Mitsuhashi S (2008), Mitsuhashi S (2008), Fujita H (2014), Lee SH (2012), Jackson SS (2014), Tokunaga F (2011), Criollo A (2010), Emmerich CH (2013), Liu D (2014), Hein MY (2015), Medunjanin S (2016), Huttlin EL (2017), Nowicka AM (2016), Rushe M (2008), Bal E (2017)	57
USP7	14	PDCD6IP	3	affinity chromatography technology	Kessler BM (2007)	1
XPO1	8	RELA	1	affinity chromatography technology	Kirli K (2015)	1
XPO1	8	CHUK	5	affinity chromatography technology	Kirli K (2015)	1
CCDC40	6	APP	1	pull down	Olah J (2011)	1
TEK	2	APP	1	pull down	Olah J (2011)	1
NFKB1	2	IKBKG	0	affinity chromatography technology, pull down	Bouwmeester T (2004), Smolle M (2004)	2
SSSCA1	0	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
NFKB1	2	TNIP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Bouwmeester T (2004), Lang V (2004), Lang V (2004), Lang V (2004), Lang V (2004), Wang J (2011), Li X (2015)	7
NCOR2	12	TNIP2	1	two hybrid	Albers M (2005)	1
TNIP2	1	IKBKB	1	affinity chromatography technology, affinity chromatography technology	Leotoing L (2011), Leotoing L (2011)	2
RAB11FIP4	2	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
CDKN1A	1	EP300	36	pull down, affinity chromatography technology	Cazzalini O (2008), Cazzalini O (2008)	2
CDKN1A	1	TNIP2	1	two hybrid	Wang J (2011)	1
FBXO25	1	TNIP2	1	enzymatic study	Teixeira FR (2013)	1
IKBKB	1	RELA	1	enzymatic study, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology	Buss H (2004), Schwabe RF (2005), Dan HC (2008), Chen TC (2014), Busch F (2012)	5
NCOR2	12	EP300	36	affinity chromatography technology	Cowger JJ (2006)	1
NFKB1	2	NCOR2	12	imaging technique	Hoberg JE (2004)	1
XPO1	8	NFKB1	2	affinity chromatography technology	Kirli K (2015)	1
SRPK2	1	CLK1	1	enzymatic study	Varjosalo M (2013)	1
SMURF1	4	TNIP2	1	enzymatic study	Andrews PS (2010)	1
DKK3	3	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
IKBKG	0	TEK	2	pull down	Fenner BJ (2010)	1
NFKB2	3	RELB	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Bouwmeester T (2004), Thornburg NJ (2003), Busino L (2012), Busino L (2012), Arabi A (2012), Huttlin EL (2017)	7
XPO1	8	RELB	1	affinity chromatography technology	Kirli K (2015)	1
TNFAIP3	3	NFKB2	3	affinity chromatography technology	Yamaguchi N (2013)	1
NCOR2	12	CDKN1A	1	affinity chromatography technology	Thorne JL (2011)	1
MAP3K8	2	CHUK	5	enzymatic study, affinity chromatography technology	Lin X (1999), Lin X (1999)	2
CDKN1A	1	IKBKG	0	two hybrid	Journo C (2009)	1
TNIP2	1	CHUK	5	affinity chromatography technology, affinity chromatography technology, enzymatic study	Leotoing L (2011), Leotoing L (2011), Leotoing L (2011)	3
TNFAIP3	3	CHUK	5	affinity chromatography technology	Zetoune FS (2001)	1
NFKB2	3	TNIP2	1	affinity chromatography technology	Bouwmeester T (2004)	1
NFKB2	3	CHUK	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Liang C (2006), Xiao G (2004), Qing G (2007), Nadiminty N (2006)	4
CCDC40	6	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
REL	5	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Hansen SK (1994), Hansen SK (1994), Liss AS (2002), Liss AS (2002), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	8
XPO1	8	NFKB2	3	affinity chromatography technology	Kirli K (2015)	1
REL	5	TNIP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Huttlin EL (2015), Huttlin EL (2017)	3
USP7	14	TNIP2	1	affinity chromatography technology	Bhattacharya S (2015)	1
SMURF1	4	APP	1	pull down	Olah J (2011)	1
TNIP2	1	IKBKG	0	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, two hybrid	Liu WK (2004), Liu WK (2004), Liu WK (2004), Liu WK (2004), Liu WK (2004), Wang J (2011)	6
STK11	2	APP	1	pull down	Olah J (2011)	1
SMARCD1	5	TNIP2	1	two hybrid, two hybrid	Chien CY (2003), Chien CY (2003)	2
MAP3K8	2	NFKB1	2	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Belich MP (1999), Bouwmeester T (2004), Belich MP (1999), Belich MP (1999), Lang V (2004), Lang V (2004), Eliopoulos AG (2006), Wang J (2011), So J (2015)	9
UBC	7	TNIP2	1	unspecified method, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down	Laplantine E (2009), Wagner S (2008), Fenner BJ (2009), Komander D (2009), Lin SM (2017), Lin SM (2017)	6
IKBKG	0	TNFAIP3	3	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Zhang SQ (2000), Zhang SQ (2000), Skaug B (2011), Skaug B (2011), Klinkenberg M (2001), Verhelst K (2012), Verhelst K (2012), Wang J (2011), Zilberman-Rudenko J (2016)	9
PDCD6IP	3	TNIP2	1	two hybrid	Wang J (2011)	1
RELA	1	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Colleran A (2013), Colleran A (2013), Colleran A (2013)	3
CDKN1A	1	APP	1	pull down	Olah J (2011)	1
MAPK1	1	PDCD6IP	3	affinity chromatography technology	Varjosalo M (2013)	1
FBXO25	1	XPO1	8	affinity chromatography technology	Teixeira FR (2010)	1
IKBKG	0	RELA	1	enzymatic study	Dan HC (2008)	1
MAPK1	1	TNIP2	1	two hybrid	Wang J (2011)	1
SRPK2	1	APP	1	pull down	Olah J (2011)	1
MAP3K8	2	RELA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Veena MS (2014), So J (2015)	3
NFKB1	2	RELB	1	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Bouwmeester T (2004), Bouwmeester T (2004), Wang J (2011), Huttlin EL (2017)	4
CLK1	1	TNIP2	1	enzymatic study	Lipp JJ (2015)	1
RELB	1	SMARCD1	5	affinity chromatography technology	Huttlin EL (2017)	1
EMILIN1	1	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	CHUK	5	imaging technique	Hao L (2010)	1
C16orf71	1	TNIP2	1	affinity chromatography technology	Huttlin EL (2017)	1
CHUK	5	RELA	1	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Hoberg JE (2006), Buss H (2004), Li S (2011), Dan HC (2008), Huang WC (2007), Busch F (2012)	6
PSMD9	0	TNIP2	1	two hybrid	Wang J (2011)	1
EP300	36	RELA	1	enzymatic study, two hybrid, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Hiroi M (2003), Nicot C (2001), Kim RH (2001), Hassa PO (2008), Hassa PO (2008), Hu J (2004), Naeaer AM (1999), Lee IT (2010), Nehra R (2010), Hsu HC (2007), Hsu HC (2007), Saha RN (2007), Saha RN (2007), Hassa PO (2003), Hassa PO (2003), Mendonca DB (2011), Chen W (2008), Chen LF (2002), OHara A (2014), Lu Y (2013), Lu Y (2013), Ren YB (2015), Chen LF (2005), Chen LF (2005), Chen LF (2005), Deng WG (2003)	31
XPO1	8	REL	5	affinity chromatography technology	Kirli K (2015)	1
USP35	3	TNIP2	1	affinity chromatography technology, affinity chromatography technology	Liu C (2015), Liu C (2015)	2
TNIP2	1	APP	1	pull down	Olah J (2011)	1
CHUK	5	NCOR2	12	enzymatic study, enzymatic study	Hoberg JE (2006), Hoberg JE (2004)	2
IKBKB	1	NFKB1	2	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique	Heissmeyer V (2001), Heissmeyer V (1999), Beinke S (2002), Beinke S (2002), Beinke S (2002), Chen TC (2014)	6
MAP3K8	2	TNIP2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Bouwmeester T (2004), Lang V (2004), Lang V (2004), Lang V (2004), So J (2015)	5
MAP3K8	2	NFKB2	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Bouwmeester T (2004), So J (2015)	3
UBC	7	IKBKG	0	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Dynek JN (2010), Dynek JN (2010), Chiaravalli J (2011), Laplantine E (2009), Hubeau M (2011), Lo YC (2009), Ikeda F (2010), Cordier F (2009), Cordier F (2009), Cordier F (2009), Renner F (2011), Fenner BJ (2009), Fenner BJ (2009), Ivins FJ (2009), Rahighi S (2009), Rahighi S (2009), Zhu G (2007), Zhu G (2007), Niu J (2011), Keusekotten K (2013), van Wijk SJ (2013), Hooper C (2014), Wagner S (2008), Saul VV (2014), Gleason CE (2011), Komander D (2009), Kensche T (2012), Skaug B (2011), Ea CK (2006), Ea CK (2006), Lo YC (2009), Laplantine E (2009), Laplantine E (2009), Emmerich CH (2013), Dubosclard V (2015), Vincendeau M (2015), Vincendeau M (2016), Zhang X (2017), Fang R (2017), Kliza K (2017), Joo D (2016), Fang R (2017), Hauenstein AV (2017)	43
UBC	7	CHUK	5	pull down	Zhang X (2017)	1
TEK	2	TNIP2	1	two hybrid, affinity chromatography technology	Hughes DP (2003), Hughes DP (2003)	2
NFKB1	2	CHUK	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Heissmeyer V (1999), Beinke S (2002), Beinke S (2002), Beinke S (2002)	4
EP300	36	MAPK1	1	affinity chromatography technology, enzymatic study, enzymatic study	Chen YJ (2007), Chen YJ (2007), Sang N (2003)	3
REL	5	MAP3K8	2	affinity chromatography technology	Bouwmeester T (2004)	1
RELB	1	RELA	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Bouwmeester T (2004), Lee ST (2011), Lee ST (2011), Chen TC (2014), Huttlin EL (2017)	5
SRPK2	1	TNIP2	1	enzymatic study	Varjosalo M (2013)	1
IKBKB	1	CHUK	5	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Zandi E (1997), Chen G (2002), Otsuki T (2002), May MJ (2000), May MJ (2000), Woronicz JD (1997), Woronicz JD (1997), Deng L (2000), Yeung KC (2001), Mercurio F (1997), Mercurio F (1997), Rothwarf DM (1998), Wu ZH (2010), Li S (2011), Li S (2011), May MJ (2002), Heilker R (1999), Leotoing L (2011), McKenzie FR (2000), Zandi E (1998), Lee DF (2007), Li XH (2001), Yeh PY (2011), Yeh PY (2011), Stehlik C (2002), Li Q (2006), So J (2015), Chen TC (2014), Karim ZA (2015), Huttlin EL (2017)	30
IKBKG	0	USP7	14	affinity chromatography technology, affinity chromatography technology	Daubeuf S (2009), Li T (2014)	2
CCDC40	6	PSMD9	0	affinity chromatography technology	Huttlin EL (2017)	1
USP7	14	UBC	7	enzymatic study, enzymatic study, unspecified method, enzymatic study, pull down	Bremm A (2010), Faesen AC (2011), Ernst A (2013), Holowaty MN (2003), Kwasna D (2018)	5
RELA	1	TNIP2	1	affinity chromatography technology	Bouwmeester T (2004)	1
NCOR2	12	RELA	1	two hybrid, affinity chromatography technology, two hybrid, two hybrid, pull down, pull down, pull down	Espinosa L (2003), Espinosa L (2003), Lee SK (2000), Lee SK (2000), Lee SK (2000), Lee SK (2000), Hoberg JE (2006)	7
IKBKB	1	IKBKG	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, biochemical, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, pull down, affinity chromatography technology	Chen G (2002), Chen G (2002), Chariot A (2002), Wu RC (2002), Deng L (2000), Shifera AS (2008), Fenner BJ (2010), Fenner BJ (2010), Fenner BJ (2010), Lee KY (2005), Rothwarf DM (1998), Ea CK (2006), Thurston TL (2009), Orel L (2010), Wu ZH (2010), Napolitano G (2009), Liu J (2009), Skaug B (2011), Li S (2011), Li S (2011), Kensche T (2012), Chiaravalli J (2011), Wu CJ (2006), Wu ZH (2006), Ahmad R (2007), Ahmad R (2007), Palkowitsch L (2008), Palkowitsch L (2008), Lo YC (2008), Mabb AM (2006), Baima ET (2010), Tegethoff S (2003), Tegethoff S (2003), Hai T (2006), Ammirante M (2010), Lee DF (2007), Rottenberg S (2002), Poyet JL (2000), Stilo R (2004), Marienfeld RB (2006), Marienfeld RB (2006), Strnad J (2006), Funakoshi-Tago M (2005), Ivins FJ (2009), Shibata Y (2012), Shibata Y (2012), Wu X (2007), Stehlik C (2002), Ryzhakov G (2007), Chen RA (2008), Wu ZH (2008), Mitsuhashi S (2008), Fujita H (2014), Golden MS (2013), Lee SH (2012), Cote SM (2013), Kim HJ (2014), Jackson SS (2014), Liao W (2008), Tokunaga F (2011), Criollo A (2010), Emmerich CH (2013), So J (2015), Liu D (2014), Guo B (2014), Guo B (2014), Guo B (2014), Zhou L (2014), Zhou L (2014), Hein MY (2015), Bagneris C (2015), Medunjanin S (2016), Huttlin EL (2017), Nowicka AM (2016), Rushe M (2008), Rushe M (2008), Hauenstein AV (2017), Bal E (2017)	78
CHUK	5	PSMD9	0	affinity chromatography technology, affinity chromatography technology, genetic interference	Sahu I (2014), Sahu I (2014), Sahu I (2014)	3
UBC	7	PDCD6IP	3	pull down	Zhang X (2017)	1
EP300	36	TNIP2	1	two hybrid	Wang J (2011)	1
MKNK1	0	TNIP2	1	two hybrid	Wang J (2011)	1
NFKB2	3	IKBKG	0	affinity chromatography technology	Bouwmeester T (2004)	1
REL	5	EP300	36	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Garbati MR (2010), Garbati MR (2010), Haery L (2014), Haery L (2014), Haery L (2014)	5