PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
TRAPPC1	0	TRAPPC10	7	two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2017), Boldt K (2016)	3
CRYAB	0	TRAPPC6A	0	two hybrid	Rolland T (2014)	1
TRAPPC6A	0	TRAPPC6B	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC6A	0	TRAPPC12	4	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	4
TRAPPC5	0	TRAPPC1	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC5	0	TRAPPC6A	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC3L	0	TRAPPC1	0	two hybrid	Scrivens PJ (2011)	1
TRAPPC2	0	TRAPPC1	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC2	0	TRAPPC5	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
HOXA1	4	TRAPPC6A	0	two hybrid	Rual JF (2005)	1
TRAPPC2	0	TRAPPC12	4	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	4
TRAPPC6B	0	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC3	0	TRAPPC6A	0	two hybrid, two hybrid, two hybrid, two hybrid	Rual JF (2005), Scrivens PJ (2011), Scrivens PJ (2011), Rolland T (2014)	4
TRAPPC5	0	TRAPPC2L	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC3	0	RAB3IP	0	affinity chromatography technology	Boldt K (2016)	1
CRYAB	0	TRAPPC2	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRAPPC12	4	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC3	0	TRAPPC6B	0	two hybrid, two hybrid, biochemical	Scrivens PJ (2011), Scrivens PJ (2011), Wan C (2015)	3
TRAPPC2	0	TRAPPC3	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC2L	0	TRAPPC12	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	3
TRAPPC2L	0	TRAPPC6B	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC6A	0	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
RAB3IP	0	TRAPPC10	7	affinity chromatography technology	Boldt K (2016)	1
TRAPPC3L	0	TRAPPC10	7	two hybrid	Scrivens PJ (2011)	1
TRAPPC3L	0	TRAPPC6B	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC3L	0	TRAPPC6A	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
EFS	2	TRAPPC6A	0	two hybrid	Rual JF (2005)	1
TRAPPC3L	0	TRAPPC12	4	two hybrid	Scrivens PJ (2011)	1
RAB3IP	0	TRAPPC2L	0	affinity chromatography technology	Boldt K (2016)	1
TRAPPC2	0	TRAPPC2L	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC1	0	TRAPPC3	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017), Boldt K (2016)	4
TRAPPC1	0	TRAPPC12	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	3
TRAPPC12	4	TRAPPC5	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRAPPC12	4	TRAPPC3	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRAPPC3	0	TRAPPC2L	0	two hybrid, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Choi C (2011), Scrivens PJ (2011), Scrivens PJ (2011), Rolland T (2014), Boldt K (2016)	6
TRAPPC2	0	TRAPPC3L	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC5	0	TRAPPC10	7	two hybrid, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2017)	2
TRAPPC12	4	TRAPPC6B	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Scrivens PJ (2011), Huttlin EL (2015), Huttlin EL (2017)	3
TRAPPC1	0	TRAPPC6B	0	affinity chromatography technology	Huttlin EL (2017)	1
IKZF3	1	TRAPPC6A	0	two hybrid	Rolland T (2014)	1
TRAPPC2	0	TRAPPC10	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
SSSCA1	0	TRAPPC6A	0	two hybrid	Rual JF (2005)	1
TRAPPC2L	0	TRAPPC6A	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC2	0	TRAPPC6B	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC2L	0	TRAPPC10	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Boldt K (2016)	3
TRAPPC3L	0	TRAPPC5	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC1	0	TRAPPC2L	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2017), Boldt K (2016)	2
TRAPPC6A	0	ZMIZ2	1	two hybrid	Rolland T (2014)	1
TRAPPC5	0	TRAPPC6B	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC2	0	TRAPPC6A	0	two hybrid, two hybrid, affinity chromatography technology	Scrivens PJ (2011), Scrivens PJ (2011), Huttlin EL (2017)	3
TRAPPC3	0	TRAPPC5	0	two hybrid, biochemical, affinity chromatography technology	Scrivens PJ (2011), Wan C (2015), Huttlin EL (2017)	3
TRAPPC6A	0	RAB3IP	0	two hybrid	Rolland T (2014)	1
TRAPPC2L	0	TRAPPC3L	0	two hybrid, two hybrid	Scrivens PJ (2011), Scrivens PJ (2011)	2
TRAPPC1	0	RAB3IP	0	affinity chromatography technology	Boldt K (2016)	1
RAD54B	3	TRAPPC6A	0	two hybrid	Rual JF (2005)	1
TRAPPC1	0	TRAPPC6A	0	affinity chromatography technology	Huttlin EL (2017)	1
TRAPPC6A	0	TRAPPC6A	0	two hybrid	Scrivens PJ (2011)	1
TRAPPC3	0	TRAPPC10	7	affinity chromatography technology	Boldt K (2016)	1