PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
NR1H4	0	XRCC6	3	affinity chromatography technology, pull down, affinity chromatography technology	Ohno M (2009), Ohno M (2009), Ohno M (2009)	3
ELF3	0	XRCC6	3	affinity chromatography technology, pull down	Wang H (2004), Wang H (2004)	2
H2AFX	1	DHX9	3	affinity chromatography technology, pull down, affinity chromatography technology	Mischo HE (2005), Mischo HE (2005), Mischo HE (2005)	3
XRCC6	3	ORC2	0	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
TERF2	2	YY1	7	affinity chromatography technology	Giannone RJ (2010)	1
CEBPA	0	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology	Yin H (2006), Yin H (2006), Yin H (2006)	3
ELF3	0	XRCC5	5	affinity chromatography technology, pull down	Wang H (2004), Wang H (2004)	2
XRCC6	3	YY1	7	affinity chromatography technology, affinity chromatography technology	Sucharov CC (2004), Sucharov CC (2004)	2
NCOA6	6	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Ko L (2000), Ko L (2003)	2
H2AFX	1	PPM1G	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo K (2008), Heo K (2008), Huttlin EL (2017)	3
DHX9	3	XRCC5	5	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Q (2005), Zhang S (2004), Zhang S (2004), Zhang S (2004), Sand-Dejmek J (2011)	5
EP300	36	TERF2	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Her YR (2013), Her YR (2013), Her YR (2013), Her YR (2013)	4
HIST1H3E	0	PCNA	0	biochemical	Campos EI (2015)	1
HOXB7	2	XRCC6	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Rubin E (2007), Rubin E (2007), Rubin E (2007), Rubin E (2007)	4
EP300	36	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, pull down, genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pao GM (2000), Pao GM (2000), Pao GM (2000), Pao GM (2000), Fan S (2002), Fan S (2002), Ma Y (2010), Subbaramaiah K (2011), Subbaramaiah K (2012)	9
EP300	36	MDC1	8	affinity chromatography technology	Jung SY (2005)	1
DDB2	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, imaging technique	Fantini D (2017), Fantini D (2017), Fantini D (2017), Fantini D (2017), Fantini D (2017)	5
TMPO	0	DHX9	3	affinity chromatography technology	Brady GF (2018)	1
ORC3	3	ORC6	0	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Kneissl M (2003), Kneissl M (2003), Vashee S (2001), Sibani S (2005), Sibani S (2005), Ramachandran N (2004)	6
BRCA1	7	5430	0	affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Krum SA (2003), Scully R (1997), Scully R (1997), Chiba N (2001), Chiba N (2001), Krum SA (2003), Starita LM (2005), Woods NT (2012), Bennett CB (2008), Hill SJ (2014), Winton CE (2016)	11
NCOA6	6	CEBPA	0	affinity chromatography technology	Hong S (2001)	1
ATR	6	WRN	6	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Otterlei M (2006), Patro BS (2011), Patro BS (2011)	4
XRCC5	5	BARD1	4	affinity chromatography technology, affinity chromatography technology	Wei L (2008), Woods NT (2012)	2
HIST1H3E	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology, biochemical	Drane P (2010), Shuaib M (2010), Campos EI (2015)	3
DDB2	1	EP300	36	affinity chromatography technology, affinity chromatography technology	Datta A (2001), Rapic-Otrin V (2002)	2
SSRP1	1	5430	0	affinity chromatography technology	Birch JL (2009)	1
YY1	7	PRKDC	12	biochemical	Wu S (2007)	1
BARD1	4	H2AFX	1	pull down	Mallery DL (2002)	1
PARP1	3	APLF	3	pull down, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kanno S (2007), Kanno S (2007), Eustermann S (2010), Ahel I (2008), Huttlin EL (2015), Gibbs-Seymour I (2016), Huttlin EL (2017)	7
EP300	36	PARP1	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Messner S (2009), Hassa PO (2005), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008), Hassa PO (2003), Hassa PO (2003), Hassa PO (2003), Kim BK (2014), Kim BK (2014)	11
XRCC4	0	LIG4	0	two hybrid, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology	Deshpande RA (2007), Deshpande RA (2007), Sibanda BL (2001), Drouet J (2005), Huang J (2002), Nick McElhinny SA (2000), Wang YG (2004), Wang YG (2004), Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	11
TOP1	1	BARD1	4	unspecified method	Trzcinska AM (2002)	1
ATR	6	TERT	7	genetic interference	Xie L (2013)	1
PRKDC	12	WRN	6	unspecified method, affinity chromatography technology, enzymatic study	Kim ST (1999), Karmakar P (2002), Karmakar P (2002)	3
PARP1	3	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Sand-Dejmek J (2011), Wu T (2013)	11
RNF146	4	SSRP1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XRCC6	3	BARD1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Feki A (2005), Feki A (2005), Woods NT (2012)	3
ERG	1	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Brenner JC (2011), Brenner JC (2011), Wang S (2014), Wang S (2014)	4
SUPT16H	4	TOP1	1	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
XRCC5	5	TOP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sand-Dejmek J (2011), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	5
ORC6	0	ORC2	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kneissl M (2003), Vashee S (2001), Vashee S (2001), Sibani S (2005), Sibani S (2005), Keller C (2002), Huttlin EL (2015), Huttlin EL (2017)	8
SIRT6	2	XRCC6	3	affinity chromatography technology, affinity chromatography technology	McCord RA (2009), McCord RA (2009)	2
HIST1H3E	0	TMPO	0	affinity chromatography technology	Campos EI (2015)	1
HIST1H3E	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology, biochemical	Drane P (2010), Shuaib M (2010), Campos EI (2015)	3
XRCC5	5	YY1	7	affinity chromatography technology, affinity chromatography technology	Sucharov CC (2004), Sucharov CC (2004)	2
TERF2	2	TERF2IP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, imaging technique	OConnor MS (2004), OConnor MS (2004), OConnor MS (2004), Li B (2000), Zhu XD (2000), Zhu XD (2000), Chen Y (2011), Chen Y (2011), Chen Y (2011), Chen Y (2011), Liu D (2004), Liu D (2004), Liu D (2004), Ye JZ (2004), Ye JZ (2004), Lee OH (2011), Lee OH (2011), Her YR (2009), Havugimana PC (2012), Her YR (2013), Wan C (2015), Hein MY (2015), Her J (2015), Arat N Oe (2012), Li JS (2017), Jeong YY (2016), Ilic A (2017), Ilic A (2017)	28
PRKDC	12	PGR	1	enzymatic study, affinity chromatography technology	Sartorius CA (2000), Sartorius CA (2000)	2
BMI1	0	YY1	7	affinity chromatography technology	Cao Q (2014)	1
SIRT6	2	TRIM25	5	affinity chromatography technology	Simeoni F (2013)	1
XRCC5	5	TMPO	0	affinity chromatography technology, affinity chromatography technology	Sand-Dejmek J (2011), Brady GF (2018)	2
PCNA	0	DHX9	3	affinity chromatography technology	Takasaki Y (2001)	1
XRCC5	5	COIL	1	affinity chromatography technology, affinity chromatography technology, pull down	Velma V (2010), Velma V (2010), Velma V (2010)	3
ATR	6	EP300	36	affinity chromatography technology, affinity chromatography technology, pull down	Stauffer D (2007), Stauffer D (2007), Stauffer D (2007)	3
CUL7	4	TOP1	1	affinity chromatography technology	Hanson D (2014)	1
APLF	3	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRIM25	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
PGR	1	XRCC5	5	pull down, enzymatic study, affinity chromatography technology	Sartorius CA (2000), Sartorius CA (2000), Sartorius CA (2000)	3
BRCA1	7	H2AFX	1	pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, enzymatic study, affinity chromatography technology, imaging technique	Mallery DL (2002), Paull TT (2000), Ray A (2009), Tsai WB (2008), Mok MT (2010), Nelson AC (2010), Chen A (2002), Dutta D (2015), Dutta D (2015)	9
NCOA6	6	PRKDC	12	affinity chromatography technology, enzymatic study	Ko L (2000), Ko L (2000)	2
TERF2	2	ORC3	3	pull down	Tatsumi Y (2008)	1
TRIM25	5	PRKDC	12	affinity chromatography technology	Choudhury NR (2017)	1
APLF	3	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Gibbs-Seymour I (2016), Huttlin EL (2017)	3
CUL7	4	TMPO	0	affinity chromatography technology	Hanson D (2014)	1
CHD1L	5	SSRP1	1	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	5430	0	affinity chromatography technology, affinity chromatography technology	Cho H (1998), Fousteri M (2006)	2
HIF1A	1	SENP3	1	affinity chromatography technology	Huang C (2009)	1
BRCA1	7	RFC1	1	biochemical, affinity chromatography technology	Wang Y (2000), Hill SJ (2014)	2
MDC1	8	PRKDC	12	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology	Lou Z (2004), Lou Z (2004), Lou Z (2004), Lou Z (2004)	4
XRCC5	5	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matheos D (2002), Ohta S (2002), Balajee AS (2001)	3
XRCC4	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Drouet J (2005)	2
RNF146	4	CHD1L	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TERT	7	XRCC6	3	affinity chromatography technology, pull down	Chai W (2002), Chai W (2002)	2
POU2F1	5	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Schild-Poulter C (2001), Matheos D (2002), Schaffer A (2003)	3
WRN	6	CHAF1A	1	far western blotting, far western blotting, imaging technique, affinity chromatography technology, affinity chromatography technology	Jiao R (2007), Jiao R (2007), Jiao R (2007), Jiao R (2007), Jiao R (2007)	5
PRKDC	12	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, affinity chromatography technology	Shao RG (1999), Drouet J (2005), Gottlieb TM (1993), Shamanna RA (2011), Shamanna RA (2011), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Hein MY (2015)	9
COIL	1	XRCC6	3	pull down	Velma V (2010)	1
CUL7	4	SSRP1	1	affinity chromatography technology	Hanson D (2014)	1
PARP1	3	SUPT16H	4	enzymatic study	Huang JY (2006)	1
CHAF1A	1	PCNA	0	pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Moggs JG (2000), Rolef Ben-Shahar T (2009), Gerard A (2006), Gerard A (2006), Gerard A (2006), Naryzhny SN (2005), Sarraf SA (2004), Hoek M (2011), Hoek M (2011), Takami Y (2007), Hein MY (2015)	11
XRCC6	3	TERF2	2	two hybrid, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology	Song K (2000), Song K (2000), Song K (2000), Lee OH (2011), Hein MY (2015)	5
SENP3	1	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2012), Wang Y (2012), Huang C (2009)	3
HIST1H3E	0	CHAF1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, biochemical, affinity chromatography technology	Drane P (2010), Drane P (2010), Polo SE (2006), Polo SE (2006), Ray-Gallet D (2011), Campos EI (2015), Campos EI (2015)	7
NCOA6	6	XRCC6	3	affinity chromatography technology, affinity chromatography technology, pull down	Ko L (2000), Ko L (2003), Ko L (2003)	3
EHF	0	XRCC6	3	pull down, affinity chromatography technology	Wang H (2004), Wang H (2004)	2
WRN	6	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Orren DK (2001), Li B (2004), Li B (2004), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Partridge JJ (2003), Partridge JJ (2003), Hein MY (2015)	14
CUL7	4	DHX9	3	affinity chromatography technology	Hanson D (2014)	1
OBSL1	9	TOP1	1	affinity chromatography technology	Hanson D (2014)	1
TRIM25	5	TOP1	1	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
XRCC6	3	NAA15	9	affinity chromatography technology	Willis DM (2002)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
TRIM25	5	DHX9	3	affinity chromatography technology	Choudhury NR (2017)	1
ERG	1	TOP1	1	affinity chromatography technology, pull down	Wang S (2014), Wang S (2014)	2
BRCA1	7	HSPB1	2	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	POU2F1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Fan W (2002), Hosey AM (2007), Hosey AM (2007), Harte MT (2010)	4
TMPO	0	PRKDC	12	affinity chromatography technology	Brady GF (2018)	1
RNF146	4	PARP1	3	affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Kang HC (2011), Kang HC (2011), Kang HC (2011), Kang HC (2011), Huttlin EL (2015), Huttlin EL (2017)	6
PRKDC	12	PDX1	2	enzymatic study	Lebrun P (2005)	1
TERF2IP	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), OConnor MS (2004), Liu D (2004)	3
TRIM25	5	HSPB1	2	affinity chromatography technology	Choudhury NR (2017)	1
EP300	36	PRKDC	12	pull down	Karmakar S (2010)	1
PDX1	2	XRCC5	5	affinity chromatography technology, pull down	Lebrun P (2005), Lebrun P (2005)	2
EP300	36	TFAP2A	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Braganca J (2003), Braganca J (2003), Shi D (2015)	3
ORC4	1	XRCC6	3	affinity chromatography technology	Sibani S (2005)	1
SPTA1	10	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
OBSL1	9	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Hanson D (2014), Hanson D (2014)	2
TERT	7	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology	Chai W (2002), Chai W (2002), Ponnala S (2011)	3
BMI1	0	TRIM25	5	affinity chromatography technology	Cao Q (2014)	1
LIG4	0	APLF	3	pull down, affinity chromatography technology, affinity chromatography technology	Kanno S (2007), Huttlin EL (2015), Huttlin EL (2017)	3
SSRP1	1	SUPT16H	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Birch JL (2009), Tan BC (2006), Tan BC (2006), Pavri R (2006), Huang JY (2006), Huang JY (2006), OConnell BC (2010), Havugimana PC (2012), Kristensen AR (2012), Wan C (2015), Huttlin EL (2017), Boldt K (2016)	12
NR1H4	0	PRKDC	12	affinity chromatography technology, pull down, affinity chromatography technology	Ohno M (2009), Ohno M (2009), Ohno M (2009)	3
TERF2	2	PPM1G	1	two hybrid	Lee OH (2011)	1
XRCC5	5	DCLRE1C	3	affinity chromatography technology, affinity chromatography technology	Drouet J (2006), Drouet J (2006)	2
RNF146	4	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Kang HC (2011), Kang HC (2011)	2
PRKDC	12	BRCA1	7	unspecified method	Kim ST (1999)	1
BRCA1	7	TERF2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ballal RD (2009), Ballal RD (2009), Hill SJ (2014)	3
PRKDC	12	HIF1A	1	affinity chromatography technology	Um JH (2004)	1
MACROD1	0	SUPT16H	4	affinity chromatography technology	Huttlin EL (2017)	1
TYK2	1	HSPB1	2	affinity chromatography technology	So J (2015)	1
BRCA1	7	TONSL	4	affinity chromatography technology, genetic interference, genetic interference, imaging technique, affinity chromatography technology	Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014)	5
HIST1H3E	0	SUPT16H	4	affinity chromatography technology	Campos EI (2015)	1
MDC1	8	XRCC5	5	pull down, affinity chromatography technology	Lou Z (2004), Lou Z (2004)	2
XRCC5	5	ORC3	3	affinity chromatography technology, affinity chromatography technology, imaging technique	Sibani S (2005), Sibani S (2005), Sibani S (2005)	3
GZMA	1	XRCC6	3	enzymatic study, affinity chromatography technology, pull down	Zhu P (2006), Zhu P (2006), Zhu P (2006)	3
MDC1	8	H2AFX	1	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, unspecified method, imaging technique	Stewart GS (2003), Stewart GS (2003), Xu X (2003), Lukas C (2004), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Stewart GS (2003), Stewart GS (2003), Pan MR (2011), Pei H (2011), Campbell SJ (2010), Rassoolzadeh H (2015)	13
ORC2	0	ORC4	1	two hybrid, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Dhar SK (2001), Quintana DG (1997), Vashee S (2001), Vashee S (2001), Sibani S (2005), Keller C (2002), Ramachandran N (2004), Vermeulen M (2010)	11
H2AFX	1	SSRP1	1	affinity chromatography technology, pull down, affinity chromatography technology	Du YC (2006), Heo K (2008), Huttlin EL (2017)	3
TRIM25	5	YY1	7	affinity chromatography technology	Choudhury NR (2017)	1
PDX1	2	XRCC6	3	affinity chromatography technology, pull down	Lebrun P (2005), Lebrun P (2005)	2
TRIM25	5	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
PCNA	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ohta S (2002), Ohta S (2002), Balajee AS (2001), Nicolae CM (2014)	4
XRCC5	5	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Um JH (2004), Um JH (2004)	2
TERF2IP	1	XRCC6	3	affinity chromatography technology, two hybrid, affinity chromatography technology	OConnor MS (2004), Lee OH (2011), Hein MY (2015)	3
CHD1L	5	H2AFX	1	affinity chromatography technology, affinity chromatography technology	Gottschalk AJ (2009), Huttlin EL (2017)	2
TRIM25	5	SENP3	1	affinity chromatography technology	Choudhury NR (2017)	1
LIG3	6	XRCC6	3	affinity chromatography technology, pull down, affinity chromatography technology	Leppard JB (2003), Leppard JB (2003), Huttlin EL (2017)	3
XRCC5	5	PRKDC	12	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology	Jin S (1997), Matheos D (2002), Gell D (1999), Drouet J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Olsen BB (2012), Olsen BB (2012), Sand-Dejmek J (2011), Sartorius CA (2000), Sartorius CA (2000), Drouet J (2006), Drouet J (2006), Sibanda BL (2010), Wan C (2015), Hein MY (2015)	17
TERF2	2	H2AFX	1	two hybrid	Lee OH (2011)	1
PRKDC	12	LIG4	0	unspecified method, affinity chromatography technology, enzymatic study	Kim ST (1999), Wang YG (2004), Wang YG (2004)	3
CHD1L	5	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Gottschalk AJ (2009), Huttlin EL (2017)	2
OBSL1	9	PCNA	0	affinity chromatography technology	Hanson D (2014)	1
DCLRE1C	3	DDB2	1	affinity chromatography technology, pull down	Yan Y (2011), Yan Y (2011)	2
OBSL1	9	MDC1	8	affinity chromatography technology	Hanson D (2014)	1
EP300	36	PGR	1	affinity chromatography technology	Shiozawa T (2003)	1
RNF146	4	LIG3	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TONSL	4	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Piwko W (2010), Piwko W (2010)	2
XRCC4	0	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Drouet J (2005), Havugimana PC (2012), Wang YG (2004)	3
CHD1L	5	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gottschalk AJ (2009), Ahel D (2009), Brockschmidt A (2011), Kulkarni A (2013), Huttlin EL (2017)	5
H2AFX	1	BMI1	0	imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study	Ginjala V (2011), Pan MR (2011), Pan MR (2011), Pan MR (2011)	4
HIST1H3E	0	PRKDC	12	affinity chromatography technology, affinity chromatography technology, biochemical	Drane P (2010), Shuaib M (2010), Campos EI (2015)	3
XRCC6	3	ORC6	0	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
TMPO	0	PARP1	3	affinity chromatography technology	Brady GF (2018)	1
XRCC5	5	GZMA	1	affinity chromatography technology, pull down	Zhu P (2006), Zhu P (2006)	2
PARP1	3	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010), Pozo FM (2011), Sekimoto T (2010)	6
BMI1	0	PRKDC	12	affinity chromatography technology	Facchino S (2010)	1
BRCA1	7	PGR	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Calvo V (2011), Ma Y (2006), Ma Y (2006), Ma Y (2006), Ma Y (2006)	5
XRCC6	3	SSRP1	1	affinity chromatography technology	Huttlin EL (2017)	1
CUL7	4	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Hanson D (2014), Hanson D (2014)	2
5430	0	XRCC5	5	affinity chromatography technology, pull down	Mo X (2002), Mo X (2002)	2
HIST1H3E	0	TOP1	1	affinity chromatography technology	Drane P (2010)	1
CCDC8	1	BAZ1A	5	affinity chromatography technology	Hanson D (2014)	1
TERF2	2	ORC6	0	pull down	Tatsumi Y (2008)	1
OBSL1	9	XRCC6	3	affinity chromatography technology	Hanson D (2014)	1
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
XRCC5	5	TYK2	1	affinity chromatography technology, affinity chromatography technology	Adam L (2000), Adam L (2000)	2
BMI1	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Facchino S (2010), Cao Q (2014)	2
TRIM25	5	PCNA	0	affinity chromatography technology, affinity chromatography technology	Park JM (2014), Park JM (2014)	2
LIG3	6	PARP1	3	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Leppard JB (2003), Leppard JB (2003), Leppard JB (2003), Leppard JB (2003)	4
PCNA	0	WRN	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe	Rodriguez-Lopez AM (2003), Rodriguez-Lopez AM (2003), Huang S (2000), Kobayashi J (2010), Baynton K (2003)	5
XRCC6	3	SUPT16H	4	affinity chromatography technology	Huttlin EL (2017)	1
EP300	36	PCNA	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Hasan S (2001), Hasan S (2001), Hasan S (2001), Hong R (2003), Hong R (2003), Cazzalini O (2008), Cazzalini O (2008), Naryzhny SN (2004), Cazzalini O (2014), Cazzalini O (2014)	10
BMI1	0	PARP1	3	affinity chromatography technology	Facchino S (2010)	1
TOP1	1	LIG4	0	unspecified method	Trzcinska AM (2002)	1
HOXB7	2	PARP1	3	affinity chromatography technology, pull down	Rubin E (2007), Rubin E (2007)	2
BRCA1	7	SSRP1	1	genetic interference, imaging technique	Hill SJ (2014), Hill SJ (2014)	2
MACROD1	0	SSRP1	1	affinity chromatography technology	Huttlin EL (2017)	1
MACROD1	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Wu Z (2015), Wu Z (2015)	2
XRCC5	5	BAZ1A	5	affinity chromatography technology, pull down	Lan L (2010), Lan L (2010)	2
TERF2IP	1	PPM1G	1	two hybrid	Lee OH (2011)	1
ERG	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Brenner JC (2011), Brenner JC (2011)	2
PPM1G	1	PARP1	3	affinity chromatography technology	St-Denis N (2016)	1
SIRT6	2	PRKDC	12	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	McCord RA (2009), McCord RA (2009), McCord RA (2009), Simeoni F (2013)	4
BAZ1A	5	H2AFX	1	affinity chromatography technology	Klement K (2014)	1
CUL7	4	MDC1	8	affinity chromatography technology	Hanson D (2014)	1
XRCC6	3	LIG4	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Nick McElhinny SA (2000), Woods NT (2012), Hein MY (2015)	4
CHD1L	5	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gottschalk AJ (2009), Ahel D (2009), Ahel D (2009), Kulkarni A (2013), Huttlin EL (2017)	5
TONSL	4	SUPT16H	4	affinity chromatography technology, affinity chromatography technology, imaging technique	OConnell BC (2010), Piwko W (2010), Hill SJ (2014)	3
CCDC8	1	PARP1	3	affinity chromatography technology	Hanson D (2014)	1
XRCC5	5	SSRP1	1	affinity chromatography technology, imaging technique	Sand-Dejmek J (2011), Sand-Dejmek J (2011)	2
TOP1	1	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	4
H2AFX	1	5430	0	affinity chromatography technology	Mischo HE (2005)	1
ERG	1	XRCC4	0	affinity chromatography technology, affinity chromatography technology	Brenner JC (2011), Brenner JC (2011)	2
PCNA	0	PRKDC	12	affinity chromatography technology	Ohta S (2002)	1
ERG	1	PRKDC	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Brenner JC (2011), Brenner JC (2011), Wang S (2014), Wang S (2014)	4
H2AFX	1	KAT2A	1	affinity chromatography technology	Lee HS (2010)	1
TRIM25	5	SUPT16H	4	affinity chromatography technology	Choudhury NR (2017)	1
PARP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, genetic interference, affinity chromatography technology	Hu Y (2014), Hu Y (2014), Hu Y (2014), Shen JP (2017), Srivas R (2016), Ertych N (2016)	6
TONSL	4	SSRP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	OConnell BC (2010), OConnell BC (2010), OConnell BC (2010), Piwko W (2010), Hill SJ (2014), Huttlin EL (2017)	6
MDC1	8	WRN	6	unspecified method	Rodriguez M (2003)	1
HSPB1	2	XRCC5	5	two hybrid, affinity chromatography technology	Katsogiannou M (2014), Katsogiannou M (2014)	2
ATR	6	DCLRE1C	3	enzymatic study	Zhang X (2004)	1
PARP1	3	POU2F1	5	far western blotting, pull down, two hybrid	Nie J (1998), Nie J (1998), Nie J (1998)	3
APLF	3	SSRP1	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CEBPA	0	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Yin H (2006), Yin H (2006), Yin H (2006)	3
PPM1G	1	XRCC6	3	affinity chromatography technology, bioid, affinity chromatography technology	Yadav L (2017), Yadav L (2017), Yadav L (2017)	3
XRCC5	5	NAA15	9	affinity chromatography technology, affinity chromatography technology	Willis DM (2002), Hein MY (2015)	2
XRCC5	5	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Sand-Dejmek J (2011), Sand-Dejmek J (2011)	2
XRCC5	5	APLF	3	pull down, affinity chromatography technology, affinity chromatography technology	Kanno S (2007), Huttlin EL (2015), Huttlin EL (2017)	3
TFAP2A	1	YY1	7	affinity chromatography technology, imaging technique	Begon DY (2005), Begon DY (2005)	2
TRIM25	5	POU2F1	5	affinity chromatography technology	Choudhury NR (2017)	1
H2AFX	1	TONSL	4	affinity chromatography technology	Huttlin EL (2017)	1
XRCC5	5	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wei L (2008), Wei L (2008), Jiang G (2013), Jiang G (2013), Jiang G (2013), Ertych N (2016)	6
DCLRE1C	3	BRCA1	7	affinity chromatography technology	Zhang X (2004)	1
RNF146	4	XRCC6	3	affinity chromatography technology, affinity chromatography technology, enzymatic study	Kang HC (2011), Kang HC (2011), Kang HC (2011)	3
XRCC5	5	LIG4	0	affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Nick McElhinny SA (2000)	2
XRCC6	3	BAZ1A	5	pull down	Lan L (2010)	1
H2AFX	1	SUPT16H	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Du YC (2006), Heo K (2008), Heo K (2008), Heo K (2008), Huttlin EL (2017)	5
MACROD1	0	DHX9	3	affinity chromatography technology	Wu Z (2015)	1
H2AFX	1	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Du YC (2006), Du YC (2006), Heo K (2008), Heo K (2008), Heo K (2008), Yang X (2010), Yang X (2010), Huttlin EL (2017)	8
TONSL	4	HIST1H3E	0	affinity chromatography technology, biochemical, affinity chromatography technology	Campos EI (2015), Campos EI (2015), Campos EI (2015)	3
CHD1L	5	APLF	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ahel D (2009), Kulkarni A (2013), Huttlin EL (2015), Huttlin EL (2017)	4
XRCC5	5	RFC1	1	affinity chromatography technology, biochemical	Matheos D (2002), Wan C (2015)	2
WRN	6	H2AFX	1	affinity chromatography technology, pull down	Cheng WH (2005), Cheng WH (2005)	2
DHX9	3	XRCC6	3	affinity chromatography technology	Wang Q (2005)	1
CCDC8	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Hanson D (2014), Hanson D (2014)	2
SPTA1	10	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Sridharan DM (2006), Sridharan DM (2006)	2
DDB2	1	XRCC6	3	affinity chromatography technology	Takedachi A (2010)	1
SENP3	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Wang M (2016), Wang M (2016)	2
DHX9	3	PRKDC	12	affinity chromatography technology, enzymatic study, biochemical	Mischo HE (2005), Mischo HE (2005), Mischo HE (2005)	3
SENP3	1	SSRP1	1	affinity chromatography technology	Wang M (2016)	1
XRCC4	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Drouet J (2005), Drouet J (2005), Hein MY (2015)	3
TRIM25	5	XRCC6	3	affinity chromatography technology	Choudhury NR (2017)	1
ELF3	0	EHF	0	affinity chromatography technology	Ewing RM (2007)	1
ATR	6	LIG4	0	unspecified method	Kim ST (1999)	1
APLF	3	LIG3	6	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
SIRT6	2	XRCC5	5	affinity chromatography technology, affinity chromatography technology	McCord RA (2009), McCord RA (2009)	2
CUL7	4	SUPT16H	4	affinity chromatography technology	Hanson D (2014)	1
SSRP1	1	PARP1	3	affinity chromatography technology	Huttlin EL (2017)	1
CUL7	4	PCNA	0	affinity chromatography technology	Hanson D (2014)	1
ELF3	0	EP300	36	affinity chromatography technology	Wang H (2004)	1
BARD1	4	5430	0	affinity chromatography technology	Woods NT (2012)	1
CCDC8	1	LIG3	6	affinity chromatography technology	Hanson D (2014)	1
PRKDC	12	POU2F1	5	enzymatic study, enzymatic study	Schild-Poulter C (2007), Schild-Poulter C (2003)	2
CHD1L	5	PRKDC	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gottschalk AJ (2009), Ahel D (2009), Ahel D (2009)	3
PARP1	3	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Wu T (2013), Huttlin EL (2017)	11
HOXB7	2	XRCC5	5	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Rubin E (2007), Rubin E (2007), Rubin E (2007), Rubin E (2007)	4
CHD1L	5	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Gottschalk AJ (2009), Ahel D (2009)	2
BRCA1	7	SUPT16H	4	genetic interference, imaging technique, affinity chromatography technology	Hill SJ (2014), Hill SJ (2014), Ertych N (2016)	3
MACROD1	0	LIG3	6	affinity chromatography technology	Huttlin EL (2017)	1
ORC4	1	ORC6	0	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Sibani S (2005), Ramachandran N (2004)	5
APLF	3	XRCC4	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
DHX9	3	NAA15	9	biochemical	Wan C (2015)	1
XRCC6	3	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Um JH (2004), Um JH (2004)	2
BRCA1	7	TRIM25	5	affinity chromatography technology	Ertych N (2016)	1
BRCA1	7	NAA15	9	affinity chromatography technology	Ertych N (2016)	1
PGR	1	XRCC6	3	pull down, enzymatic study, affinity chromatography technology	Sartorius CA (2000), Sartorius CA (2000), Sartorius CA (2000)	3
XRCC6	3	ORC3	3	affinity chromatography technology, affinity chromatography technology	Sibani S (2005), Sibani S (2005)	2
HIST1H3E	0	SSRP1	1	affinity chromatography technology	Campos EI (2015)	1
H2AFX	1	LIG3	6	affinity chromatography technology	Huttlin EL (2017)	1
TOP1	1	PARP1	3	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, biochemical	Czubaty A (2005), Yung TM (2004), Yung TM (2004), Yung TM (2004), Yung TM (2004)	5
EP300	36	XRCC6	3	enzymatic study	Cohen HY (2004)	1
OBSL1	9	SUPT16H	4	affinity chromatography technology	Hanson D (2014)	1
CUL7	4	5430	0	affinity chromatography technology	Hanson D (2014)	1
PARP1	3	PRKDC	12	affinity chromatography technology	Ju BG (2006)	1
PGR	1	PARP1	3	affinity chromatography technology	Sartorius CA (2000)	1
TERF2	2	WRN	6	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology	Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Opresko PL (2002), Li B (2008)	6
H2AFX	1	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Mischo HE (2005), Mischo HE (2005), Heo K (2008), Heo K (2008), Heo K (2008), Lee HS (2010), Kobayashi J (2012), Huttlin EL (2017)	8
TONSL	4	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Piwko W (2010), Piwko W (2010)	2
EHF	0	XRCC5	5	pull down, affinity chromatography technology	Wang H (2004), Wang H (2004)	2
H2AFX	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Heo K (2008), Heo K (2008), Sand-Dejmek J (2011)	3
BRCA1	7	TOP1	1	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Shen JP (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	7
TERF2IP	1	PARP1	3	affinity chromatography technology	OConnor MS (2004)	1
XRCC5	5	ATR	6	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
MDC1	8	5430	0	unspecified method, affinity chromatography technology	Rodriguez M (2003), Woods NT (2012)	2
XRCC5	5	EP300	36	affinity chromatography technology, affinity chromatography technology	Zhang Z (2017), Zhang Z (2017)	2
CUL7	4	PARP1	3	affinity chromatography technology	Hanson D (2014)	1
CHAF1A	1	PRKDC	12	affinity chromatography technology	Hoek M (2011)	1
XRCC5	5	ORC2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matheos D (2002), Sibani S (2005), Sibani S (2005)	3
BMI1	0	SUPT16H	4	affinity chromatography technology	Cao Q (2014)	1
WRN	6	DHX9	3	pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang S (2007), Friedemann J (2005), Friedemann J (2005), Friedemann J (2005)	4
BMI1	0	BAZ1A	5	affinity chromatography technology	Abdouh M (2016)	1
NCOA6	6	EP300	36	affinity chromatography technology, pull down	Ko L (2000), Ko L (2000)	2
ORC3	3	BRCA1	7	affinity chromatography technology	Matsuoka S (2007)	1
ERG	1	TRIM25	5	pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Wang S (2016), Wang S (2016), Wang S (2016), Wang S (2016), Wang S (2016)	5
CCDC8	1	PRKDC	12	affinity chromatography technology	Hanson D (2014)	1
PRKDC	12	H2AFX	1	enzymatic study, enzymatic study, affinity chromatography technology, pull down, enzymatic study, enzymatic study	Park EJ (2003), Mischo HE (2005), Heo K (2008), Heo K (2008), Li A (2010), Kim K (2012)	6
RNF126	2	XRCC6	3	affinity chromatography technology, enzymatic study	Ishida N (2017), Ishida N (2017)	2
OBSL1	9	TMPO	0	affinity chromatography technology	Hanson D (2014)	1
MDC1	8	BARD1	4	affinity chromatography technology	Lou Z (2003)	1
CEBPA	0	XRCC6	3	pull down, affinity chromatography technology	Yin H (2006), Yin H (2006)	2
BRCA1	7	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Kang HJ (2006), Kang HJ (2006)	2
OBSL1	9	DHX9	3	affinity chromatography technology	Hanson D (2014)	1
MACROD1	0	XRCC5	5	affinity chromatography technology, affinity chromatography technology	Wu Z (2015), Wu Z (2015)	2
RFC1	1	XRCC6	3	biochemical	Wan C (2015)	1
EP300	36	NR1H4	0	enzymatic study	Kemper JK (2009)	1
CHAF1A	1	XRCC5	5	affinity chromatography technology, affinity chromatography technology, pull down, pull down	Hoek M (2011), Hoek M (2011), Hoek M (2011), Hoek M (2011)	4
PRKDC	12	DCLRE1C	3	pull down, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Ma Y (2002), Ma Y (2002), Ma Y (2002), Zhang X (2004), Ma Y (2005), Drouet J (2006), Drouet J (2006)	7
DHX9	3	SSRP1	1	biochemical	Havugimana PC (2012)	1
HSPB1	2	OBSL1	9	two hybrid	Katsogiannou M (2014)	1
RNF146	4	SUPT16H	4	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PCNA	0	TOP1	1	affinity chromatography technology	Takasaki Y (2001)	1
NCOA6	6	PARP1	3	affinity chromatography technology	Ko L (2003)	1
NR1H4	0	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology	Ohno M (2009), Ohno M (2009), Ohno M (2009)	3
TOP1	1	DDB2	1	unspecified method	Trzcinska AM (2002)	1
OBSL1	9	CCDC8	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hanson D (2011), Hanson D (2011), Hanson D (2014), Nie J (2015)	4
KAT2A	1	XRCC6	3	two hybrid, pull down, pull down, biochemical, affinity chromatography technology	Barlev NA (1998), Barlev NA (1998), Barlev NA (1998), Barlev NA (1998), Barlev NA (1998)	5
CHAF1A	1	XRCC6	3	affinity chromatography technology, pull down, pull down	Hoek M (2011), Hoek M (2011), Hoek M (2011)	3
CUL7	4	PRKDC	12	affinity chromatography technology	Hanson D (2014)	1
PARP1	3	HIF1A	1	affinity chromatography technology	Elser M (2008)	1
CCDC8	1	TMPO	0	affinity chromatography technology	Hanson D (2014)	1
ERG	1	5430	0	affinity chromatography technology, pull down	Wang S (2014), Wang S (2014)	2
HIF1A	1	CEBPA	0	imaging technique, imaging technique, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Zhao XY (2011), Zhao XY (2011), Yang L (2008), Yang L (2008), Yang L (2008), Yang L (2008)	6
PARP1	3	MACROD1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wu Z (2015), Wu Z (2015), Wu Z (2015), Wu Z (2015), Huttlin EL (2017)	5
5430	0	PCNA	0	affinity chromatography technology	Kang H (2011)	1
CCDC8	1	TRIM25	5	affinity chromatography technology	Hanson D (2014)	1
WRN	6	XRCC6	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Li B (2004), Li B (2004), Hein MY (2015), Huttlin EL (2017)	10
RFC1	1	PCNA	0	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, far western blotting, affinity chromatography technology, biochemical, affinity chromatography technology	Maruyama T (2002), Fotedar R (1996), Fotedar R (1996), Mossi R (1997), van der Kuip H (1999), Ohta S (2002), Ohta S (2002), Dahm K (2002), Havugimana PC (2012), Montecucco A (1998), Uhlmann F (1997), Dzantiev L (2004), Han J (2014), Wan C (2015), Hein MY (2015)	15
HIST1H3E	0	PARP1	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Drane P (2010), Drane P (2010), Shuaib M (2010)	3
ORC3	3	ORC4	1	biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down	Dhar SK (2001), Pinto S (1999), Vashee S (2001), Sibani S (2005), Ramachandran N (2004)	5
ATR	6	H2AFX	1	imaging technique, enzymatic study	Ray A (2009), Kim K (2012)	2
EP300	36	ORC2	0	pull down	Karmakar S (2010)	1
BARD1	4	PPM1G	1	affinity chromatography technology	Woods NT (2012)	1
OBSL1	9	SSRP1	1	affinity chromatography technology	Hanson D (2014)	1
ORC4	1	XRCC5	5	affinity chromatography technology, imaging technique	Sibani S (2005), Sibani S (2005)	2
WRN	6	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Li B (2004), Li B (2004), Li B (2004)	3
EP300	36	YY1	7	enzymatic study, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yao YL (2001), Lee JS (1995), Lee JS (1995), Lee JS (1995), Lee JS (1995), Kadeppagari RK (2009), Kadeppagari RK (2009), Kadeppagari RK (2009), Sankar N (2008), Sankar N (2008), Sankar N (2008), Wang CC (2007), Wang CC (2007), Galvin KM (1997)	14
HOXB7	2	PRKDC	12	pull down, affinity chromatography technology	Rubin E (2007), Rubin E (2007)	2
TMPO	0	LIG3	6	affinity chromatography technology	Hein MY (2015)	1
RNF126	2	XRCC5	5	affinity chromatography technology, enzymatic study	Ishida N (2017), Ishida N (2017)	2
BMI1	0	TERF2	2	affinity chromatography technology	Cao Q (2014)	1
OBSL1	9	PRKDC	12	affinity chromatography technology	Hanson D (2014)	1
POU2F1	5	XRCC6	3	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Schild-Poulter C (2001), Schild-Poulter C (2007), Schaffer A (2003), Schaffer A (2003)	4
CUL7	4	XRCC6	3	affinity chromatography technology	Hanson D (2014)	1
TFAP2A	1	XRCC6	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009)	4
TERF2	2	ORC2	0	pull down, affinity chromatography technology	Tatsumi Y (2008), Tatsumi Y (2008)	2
DHX9	3	5430	0	affinity chromatography technology, affinity chromatography technology	Tang W (2009), Fujita H (2003)	2
DHX9	3	BRCA1	7	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Schlegel BP (2003), Anderson SF (1998), Anderson SF (1998), Ertych N (2016)	4
KAT2A	1	XRCC5	5	biochemical, affinity chromatography technology	Barlev NA (1998), Barlev NA (1998)	2
EP300	36	HIF1A	1	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Lando D (2002), Freedman SJ (2002), Lewis MD (2004), Matt T (2004), Sang N (2002), Luo W (2010), Freedman SJ (2003), Bodily JM (2011), Lee YM (2009), Lee YM (2009), Lee YM (2009), Kung AL (2004), Kung AL (2004), Kung AL (2004), Land SC (2007), Zhang Y (2010), Zhang Y (2010), Fath DM (2006), Fath DM (2006), Lee SJ (2013), Wang D (2014), Kaluz S (2006), Kaluz S (2006), Kaluz S (2006), Shin DH (2008), Shin DH (2008), Wang Y (2012), Huang C (2009), Hewitson KS (2002), Cook KM (2009), Cook KM (2009), Hubbi ME (2012), Kim SY (2014), Sang N (2003), Sang N (2003), Sang N (2003), Yasinska IM (2003), Na YR (2013), Na YR (2013), Mendonca DB (2011), Arany Z (1996), Arany Z (1996), Chen R (2012), Li SH (2008), Galbraith MD (2013), Chen Z (2014), Li Q (2012), Geng H (2012), Geng H (2012), Kato H (2004), Lim JH (2010), Kyle HF (2015), Kyle HF (2015), Rath S (2016), Kimura M (2008), Dubey R (2013)	56
ORC2	0	BRCA1	7	affinity chromatography technology, affinity chromatography technology	Matsuoka S (2007), Hill SJ (2014)	2
OBSL1	9	5430	0	affinity chromatography technology	Hanson D (2014)	1
BARD1	4	PARP1	3	affinity chromatography technology	Hu Y (2014)	1
ORC2	0	ORC3	3	two hybrid, two hybrid, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology	Kneissl M (2003), Kneissl M (2003), Kneissl M (2003), Dhar SK (2001), Dhar SK (2001), Matsuoka S (2007), Pinto S (1999), Pinto S (1999), Vashee S (2001), Vashee S (2001), Sibani S (2005), Sibani S (2005), Keller C (2002), Havugimana PC (2012), Vermeulen M (2010), Wan C (2015), Hein MY (2015)	17
OBSL1	9	COIL	1	affinity chromatography technology	Hanson D (2014)	1
PRKDC	12	KAT2A	1	enzymatic study	Barlev NA (1998)	1
CUL7	4	TRIM25	5	affinity chromatography technology	Hanson D (2014)	1
BRCA1	7	TFAP2A	1	affinity chromatography technology	Buckley NE (2011)	1
BRCA1	7	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Ertych N (2016)	2
RNF126	2	NAA15	9	affinity chromatography technology	OConnor HF (2015)	1
NCOA6	6	NR1H4	0	pull down	Ananthanarayanan M (2011)	1
TFAP2A	1	XRCC5	5	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009)	4
DDB2	1	PARP1	3	affinity chromatography technology, affinity chromatography technology	Robu M (2013), Robu M (2013)	2
CCDC8	1	XRCC6	3	affinity chromatography technology	Hanson D (2014)	1
APLF	3	TOP1	1	affinity chromatography technology	Huttlin EL (2015)	1
BMI1	0	EP300	36	affinity chromatography technology	Cao Q (2014)	1
LIG3	6	XRCC5	5	affinity chromatography technology, pull down	Leppard JB (2003), Leppard JB (2003)	2
SENP3	1	PARP1	3	enzymatic study	Messner S (2009)	1
CCDC8	1	CUL7	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hanson D (2014), Nie J (2015), Nie J (2015)	3
BRCA1	7	BARD1	4	two hybrid, two hybrid, pull down, pull down, pull down, pull down, imaging technique, imaging technique, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, two hybrid, pull down, pull down, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, two hybrid, x-ray crystallography, imaging technique, imaging technique, two hybrid, affinity chromatography technology, protein complementation assay, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology	Wu LC (1996), Wang Q (2001), Wang Q (2001), Mallery DL (2002), Wu-Baer F (2003), Hashizume R (2001), Fabbro M (2002), Rodriguez JA (2004), Brzovic PS (2003), Nishikawa H (2004), Dong Y (2003), Dong Y (2003), Chiba N (2001), Kleiman FE (2001), Kleiman FE (2001), Kleiman FE (2001), Wu LC (1996), Morris JR (2002), Brzovic PS (2001), Xia Y (2003), Meza JE (1999), Kentsis A (2002), Hashizume R (2001), Fabbro M (2004), Brzovic PS (2001), Yu X (1998), Jin Y (1997), Scully R (1999), Fabbro M (2004), Kleiman FE (1999), Kleiman FE (1999), Tascou S (2003), Brzovic PS (2003), Benezra M (2003), Meza JE (1999), Cantor SB (2001), Wang Q (1998), Ryser S (2009), Ryser S (2009), Nishikawa H (2009), Nishikawa H (2009), Sobhian B (2007), Harte MT (2010), Simons AM (2006), Wei L (2008), Kumaraswamy E (2007), Kumaraswamy E (2007), Dizin E (2010), Dizin E (2010), Greenberg RA (2006), Greenberg RA (2006), Greenberg RA (2006), Zhu Q (2011), Chen A (2002), Chen A (2002), Sy SM (2009), Sy SM (2009), Nelson AC (2010), Nelson AC (2010), Morris JR (2006), Brzovic PS (2001), Mok MT (2010), Au WW (2005), Ayi TC (1998), Choudhury AD (2005), Sarkar M (2008), Sarkar M (2008), Thakar A (2010), Lu Y (2012), Kentsis A (2002), Christou CM (2014), Christou CM (2014), Sevcik J (2013), Johnson N (2013), Matsuzawa A (2014), Matsuzawa A (2014), Hill SJ (2014), Hill SJ (2014), Hill SJ (2014), Starita LM (2015), Hu Y (2014), Wu W (2015), Loke J (2015), Densham RM (2016), Boukerroucha M (2015), Huttlin EL (2017), Liang Y (2017), Liang Y (2017), Liang Y (2017), Ertych N (2016), Ertych N (2016)	91
POU2F1	5	PGR	1	pull down	Prefontaine GG (1999)	1
SUPT16H	4	WRN	6	affinity chromatography technology	Boldt K (2016)	1
OBSL1	9	CUL7	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Litterman N (2011), Litterman N (2011), Hanson D (2011), Hanson D (2011), Nie J (2015)	5
PPM1G	1	XRCC5	5	affinity chromatography technology, bioid, affinity chromatography technology	Yadav L (2017), Yadav L (2017), Yadav L (2017)	3
CCDC8	1	DHX9	3	affinity chromatography technology	Hanson D (2014)	1
MACROD1	0	H2AFX	1	affinity chromatography technology	Huttlin EL (2017)	1
H2AFX	1	HIF1A	1	affinity chromatography technology, imaging technique	Rezaeian AH (2017), Rezaeian AH (2017)	2
TERF2	2	XRCC5	5	affinity chromatography technology, affinity chromatography technology	OConnor MS (2004), Giannone RJ (2010)	2
ATR	6	BRCA1	7	pull down, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Tibbetts RS (2000), Kim ST (1999), Mu JJ (2007), Chen J (2000), Chen J (2000), Tibbetts RS (2000), Gatei M (2001), Gatei M (2001), Gatei M (2001), Tian F (2013)	10
OBSL1	9	PARP1	3	affinity chromatography technology	Hanson D (2014)	1
CCDC8	1	5430	0	affinity chromatography technology	Hanson D (2014)	1
MDC1	8	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, imaging technique, imaging technique	Matsuoka S (2007), Strauss C (2011), Strauss C (2011), Stewart GS (2003), Lou Z (2003), Mok MT (2010), Au WW (2005)	7
XRCC5	5	ORC6	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Sibani S (2005), Sibani S (2005), Sibani S (2005)	3
TOP1	1	DHX9	3	affinity chromatography technology	Czubaty A (2005)	1
TOP1	1	PRKDC	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	5
ERG	1	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Brenner JC (2011), Brenner JC (2011)	2