Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications
XBP1	7494	VALPROIC ACID	CHEMBL109		PharmGKB

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
XBP1	rs2269577	CG	Platinum compounds	efficacy	no	Patients with the CG genotype did not have a significantly increased likelihood of responding to platinum-based regimens, as compared to those with the GG genotype. "Response" was defined as patients exhibiting complete or partial response, according to the Response Evaluation Criteria in Solid Tumors (RECIST) guidelines.	Genotype CG is not associated with response to Platinum compounds in people with Carcinoma, Non-Small-Cell Lung as compared to genotype GG.	23510626	1184136041
XBP1	rs2269577	CC	Platinum compounds	efficacy	yes	Patients with the CC genotype were more likely to respond to platinum-based regimens, as compared to those with the GG genotype. "Response" was defined as patients exhibiting complete or partial response, according to the Response Evaluation Criteria in Solid Tumors (RECIST) guidelines.	Genotype CC is associated with increased response to Platinum compounds in people with Carcinoma, Non-Small-Cell Lung as compared to genotype GG.	23510626	1184136036